化学物質有害性情報データベース 物質情報

CAS 登録番号 CAS RN® : 106445
官報公示整理番号 METI No. : 2-1045
物質名 test material : p-クレゾール /4-Cresol
水溶解度 water solubility : 2.1mg/L (実測値 measured)
LogKow : 1.94 (実測値 measured)
備考 remarks
Excelファイルダウンロード (XLS:20KB)

【注意事項】
* 化学物質有害性情報データベース情報更新日が2019年9月以前はRead-acrossデータでも○としていないので、毒性値の取り扱いには注意が必要である。

                       
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) Read-across * QSAR GLP 設定濃度 実測濃度 情報源 情報源による信頼性評価 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure duration value exposure duration unit toxicity value toxicity unit Read-across QSAR GLPnominal concentration measured concentrationoriginal work type original work reliability rankauthor title referenced journal publication year Information update date
藻類 Scenedesmus subspicatus Population EC50 2 days 7800 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., and M. Pattard Results of the Harmful Effects of Water Pollutants to Green Algae (Scenedesmus subspicatus) in the Cell Multiplication Inhibition Test Water Res.24(1): 31-38 1990 2016/03/25
藻類 Scenedesmus subspicatus Population EC50 2 days 21000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., and M. Pattard Results of the Harmful Effects of Water Pollutants to Green Algae (Scenedesmus subspicatus) in the Cell Multiplication Inhibition Test Water Res.24(1): 31-38 1990 2016/03/25
甲殻類 Daphnia magna Mortality 1 days 10000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Cooper,W.E., and R.J. Stout The Monticello Experiment: A Case Study In: J.Cairns Jr.(Ed.), Multispecies Toxicity Testing, Pergamon Press Inc., Elmsford,NY:96-116 1985 2016/03/25
甲殻類 Daphnia magna Mortality 1 days 10000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Cooper,W.E., and R.J. Stout The Monticello Experiment: A Case Study In: J.Cairns Jr.(Ed.), Multispecies Toxicity Testing, Pergamon Press Inc., Elmsford,NY:96-116 1985 2016/03/25
甲殻類 Daphnia magna Behavior 2 days 12000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuhn Comparative Water-Toxicological Investigations on Bacteria, Algae, and Daphnia TR-TS-002, Literature Research Company, Annandale, VA:26 p. 1959 2016/03/25
甲殻類 Daphnia magna Physiology EC50 2 days 7700 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., M. Pattard, K.D. Pernak, and A. Winter Results of the Harmful Effects of Selected Water Pollutants (Anilines, Phenols, Aliphatic Compounds) to Daphnia magna Water Res.23(4): 495-499 1989 2016/03/25
甲殻類 Daphnia magna Behavior EC50 1 days 4900 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R. Schadstoffwirkungen von Umweltchemikalien im Daphnien-Reproduktions-Test als Grundlage fr die Bewertung der Umweltgefhrlichkeit in Aquatischen Sys Forschungsbericht 10603052, Mrz: 1988 2016/03/25
甲殻類 Daphnia magna Physiology EC50 1 days 4900 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., M. Pattard, K.D. Pernak, and A. Winter Results of the Harmful Effects of Water Pollutants to Daphnia magna in the 21 Day Reproduction Test Water Res.23(4): 501-510 1989 2016/03/25
甲殻類 Daphnia magna Physiology EC50 1 days 0.115 mmol/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Devillers,J. Acute Toxicity of Cresols, Xylenols, and Trimethylphenols to Daphnia magna Straus 1820 Sci. Total Environ.76(1): 79-83 1988 2016/03/25
甲殻類 Daphnia magna Behavior EC0 1 days 2500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R. Schadstoffwirkungen von Umweltchemikalien im Daphnien-Reproduktions-Test als Grundlage fr die Bewertung der Umweltgefhrlichkeit in Aquatischen Sys Forschungsbericht 10603052, Mrz: 1988 2016/03/25
甲殻類 Daphnia magna Physiology EC50 1 days 14000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., M. Pattard, K.D. Pernak, and A. Winter Results of the Harmful Effects of Selected Water Pollutants (Anilines, Phenols, Aliphatic Compounds) to Daphnia magna Water Res.23(4): 495-499 1989 2016/03/25
甲殻類 Daphnia magna Mortality LC50 2 days 1400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Parkhurst,B.R., A.S. Bradshaw, J.L. Forte, and G.P. Wright An Evaluation of the Acute Toxicity to Aquatic Biota of a Coal Conversion Effluent and its Major Components Bull. Environ. Contam. Toxicol.23(3): 349-356 1979 2016/03/25
甲殻類 Daphnia magna Behavior NOEC 21 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R. Schadstoffwirkungen von Umweltchemikalien im Daphnien-Reproduktions-Test als Grundlage fr die Bewertung der Umweltgefhrlichkeit in Aquatischen Sys Forschungsbericht 10603052, Mrz: 1988 2016/03/25
甲殻類 Daphnia magna Reproduction NOEC 21 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., M. Pattard, K.D. Pernak, and A. Winter Results of the Harmful Effects of Water Pollutants to Daphnia magna in the 21 Day Reproduction Test Water Res.23(4): 501-510 1989 2016/03/25
甲殻類 Daphnia magna Mortality LC50 1 days 13510 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kim,B.C., K.S. Park, S.D. Kim, and M.B. Gu Evaluation of a High Throughput Toxicity Biosensor and Comparison with a Daphnia magna Bioassay Biosens. Bioelectron.18(5/6): 821-826 2003 2016/03/25
甲殻類 Daphnia magna Mortality LC50 2 days 0.000195 その他others [M] 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kopperman,H.L., R.M. Carlson, and R. Caple Aqueous Chlorination and Ozonation Studies. I. Structure-Toxicity Correlations of Phenolic Compounds to Daphnia magna Chem.-Biol. Interact.9(4): 245-251 1974 2016/03/25
甲殻類 Daphnia magna Intoxication ET50 24 hours 8.2 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Urrestarazu Ramos, E. Aquatic toxicity of polar narcotic pollutants/ Mechanism, modeling and environmental effect assessment (PhD Thesis) 1998 2016/02/08
甲殻類 Daphnia magna Intoxication ET50 24 hours 0.319 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Urrestarazu Ramos, E. Aquatic toxicity of polar narcotic pollutants/ Mechanism, modeling and environmental effect assessment (PhD Thesis) 1998 2016/02/08
甲殻類 Daphnia magna Intoxication ET50 48 hours 12.4 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Furusjö, E., Andersson, M., Rahmberg, M., Svenson, A. Estimating environmentally important properties of chemicals from the chemical structure 2003 2016/02/08
甲殻類 Daphnia magna Mortality LC50 48 hours 17.1 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Peter C. von der Ohe, Ralph Kühne, Ralf-Uwe Ebert, Rolf Altenburger, Matthias Liess, and Gerrit Schüürmann Structural Alerts-A New Classification Model to Discriminate Excess Toxicity from Narcotic Effect Levels of Organic Compounds in the Acute Daphnid Assay 2005 2016/02/08
甲殻類 Daphnia magna Lethal LOEC 504 hours 3.162 mg/L 9 ECETOC Aquatic Toxicity, EAT Kühn ea 89 2016/02/08
甲殻類 Daphnia magna Lethal NOEC 504 hours 1 mg/L 9 ECETOC Aquatic Toxicity, EAT Kühn ea 89 2016/02/08
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 4 days 69 μmol/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Hodson,P.V., D.G. Dixon, and K.L.E. Kaiser Measurement of Median Lethal Dose as a Rapid Indication of Contaminant Toxicity to Fish Environ. Toxicol. Chem.3(2): 243-254 1984 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 4 days 8600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bergman,H.L., and A.D. Anderson Effects of Aqueous Effluents from In Situ Fossil Fuel Processing Technologies on Aquatic Systems Contract No.EY-77-C-04-3913, University of Wyoming, Laramie, WY:73 p. 1977 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Physiology 2 days 28 μM 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Dixon,D.G., P.V. Hodson, and K.L.E. Kaiser Serum Sorbitol Dehydrogenase Activity as an Indicator of Chemically Induced Liver Damage in Rainbow Trout Environ. Toxicol. Chem.6(9): 685-696 1987 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Physiology 3.82 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) McKim,J., P. Schmieder, and G. Veith Absorption Dynamics of Organic Chemical Transport Across Trout Gills as Related to Octanol-Water Partition Coefficient Toxicol. Appl. Pharmacol.77:1-10 1985 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Physiology 3.82 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) McKim,J., P. Schmieder, and G. Veith Absorption Dynamics of Organic Chemical Transport Across Trout Gills as Related to Octanol-Water Partition Coefficient Toxicol. Appl. Pharmacol.77:1-10 1985 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Physiology 3.82 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) McKim,J., P. Schmieder, and G. Veith Absorption Dynamics of Organic Chemical Transport Across Trout Gills as Related to Octanol-Water Partition Coefficient Toxicol. Appl. Pharmacol.77:1-10 1985 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality 4 days 2800 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bergman,H.L., and A.D. Anderson Effects of Aqueous Effluents from In Situ Fossil Fuel Processing Technologies on Aquatic Systems Contract No.EY-77-C-04-3913, University of Wyoming, Laramie, WY:73 p. 1977 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality 4 days 11300 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bergman,H.L., and A.D. Anderson Effects of Aqueous Effluents from In Situ Fossil Fuel Processing Technologies on Aquatic Systems Contract No.EY-77-C-04-3913, University of Wyoming, Laramie, WY:73 p. 1977 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LD50 4 days 0.73 その他others [mmol/kg] 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Hodson,P.V., D.G. Dixon, and K.L.E. Kaiser Measurement of Median Lethal Dose as a Rapid Indication of Contaminant Toxicity to Fish Environ. Toxicol. Chem.3(2): 243-254 1984 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LD50 4 days 0.87 その他others [mmol/kg] 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Hodson,P.V., D.G. Dixon, and K.L.E. Kaiser Measurement of Median Lethal Dose as a Rapid Indication of Contaminant Toxicity to Fish Environ. Toxicol. Chem.3(2): 243-254 1984 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 2 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Shumway,D.L., and J.R. Palensky Impairment of the Flavor of Fish by Water Pollutants EPA-R3-73-010, U.S.EPA, Washington, D.C.:80 p. 1973 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 4 days 7900 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) DeGraeve,G.M., D.L. Geiger, J.S. Meyer, and H.L. Bergman Acute and Embryo-Larval Toxicity of Phenolic Compounds to Aquatic Biota Arch. Environ. Contam. Toxicol.9(5): 557-568 1980 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth 32 days 2570 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Barron,M.G., and I.R. Adelman Nucleic Acid, Protein Content, and Growth of Larval Fish Sublethally Exposed to Various Toxicants Can. J. Fish. Aquat. Sci.41(1): 141-150 1984 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 3 days 21000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Mattson,V.R., J.W. Arthur, and C.T. Walbridge Acute Toxicity of Selected Organic Compounds to Fathead Minnows EPA-600/3-76-097, U.S.EPA, Duluth, MN:12 p. 1976 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality 4 days 10000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Cooper,W.E., and R.J. Stout The Monticello Experiment: A Case Study In: J.Cairns Jr.(Ed.), Multispecies Toxicity Testing, Pergamon Press Inc., Elmsford,NY:96-116 1985 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality 4 days 11300 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bergman,H.L., and A.D. Anderson Effects of Aqueous Effluents from In Situ Fossil Fuel Processing Technologies on Aquatic Systems Contract No.EY-77-C-04-3913, University of Wyoming, Laramie, WY:73 p. 1977 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality 4 days 91000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bergman,H.L., and A.D. Anderson Effects of Aqueous Effluents from In Situ Fossil Fuel Processing Technologies on Aquatic Systems Contract No.EY-77-C-04-3913, University of Wyoming, Laramie, WY:73 p. 1977 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 16500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Geiger,D.L., S.H. Poirier, L.T. Brooke, and D.J. Call Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales promelas) Volume III Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI:328 p. 1986 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 19000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Mattson,V.R., J.W. Arthur, and C.T. Walbridge Acute Toxicity of Selected Organic Compounds to Fathead Minnows EPA-600/3-76-097, U.S.EPA, Duluth, MN:12 p. 1976 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 28600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bergman,H.L., and A.D. Anderson Effects of Aqueous Effluents from In Situ Fossil Fuel Processing Technologies on Aquatic Systems Contract No.EY-77-C-04-3913, University of Wyoming, Laramie, WY:73 p. 1977 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality 4 days 10000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Cooper,W.E., and R.J. Stout The Monticello Experiment: A Case Study In: J.Cairns Jr.(Ed.), Multispecies Toxicity Testing, Pergamon Press Inc., Elmsford,NY:96-116 1985 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 2 days 21000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Mattson,V.R., J.W. Arthur, and C.T. Walbridge Acute Toxicity of Selected Organic Compounds to Fathead Minnows EPA-600/3-76-097, U.S.EPA, Duluth, MN:12 p. 1976 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 1 days 26000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Mattson,V.R., J.W. Arthur, and C.T. Walbridge Acute Toxicity of Selected Organic Compounds to Fathead Minnows EPA-600/3-76-097, U.S.EPA, Duluth, MN:12 p. 1976 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 28600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) DeGraeve,G.M., D.L. Geiger, J.S. Meyer, and H.L. Bergman Acute and Embryo-Larval Toxicity of Phenolic Compounds to Aquatic Biota Arch. Environ. Contam. Toxicol.9(5): 557-568 1980 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Physiology 2 days 0.028 mM 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Dixon,D.G., C.E.A. Hill, P.V. Hodson, E.J. Kempe, and K.L.E. Kaiser Plasma Leucine Aminonaphthylamidase as an Indicator of Acute Sublethal Toxicant Stress in Rainbow Trout Environ. Toxicol. Chem.4(6): 789-796 1985 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical 4 days 400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Barron,M.G., and I.R. Adelman Nucleic Acid, Protein Content, and Growth of Larval Fish Sublethally Exposed to Various Toxicants Can. J. Fish. Aquat. Sci.41(1): 141-150 1984 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 1 hours >30000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Mattson,V.R., J.W. Arthur, and C.T. Walbridge Acute Toxicity of Selected Organic Compounds to Fathead Minnows EPA-600/3-76-097, U.S.EPA, Duluth, MN:12 p. 1976 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 96 hours 16.4 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Russom, C.L., Bradbury, S.P., Broderius, S.J., Drummond, R.A. and Hammermeister, D.E. PREDICTING MODES OF TOXIC ACTION FROM CHEMICAL STRUCTURE: ACUTE TOXICITY IN THE FATHEAD MINNOW (PIMEPHALES PROMELAS) 1997 2016/02/08
魚類 Poecilia reticulata (Guppy) Mortality LC50 96 hours 19.7 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Raevsky, O.A., and Dearden, J.C. Creation of predictive models of aquatic toxicity of environmental pollutants with different mechanisms of action on the basis of molecular similarity and hybot descriptors. 2004 2016/02/08
魚類 Pimephales promelas (Fathead minnow) Lethal EC50 96 hours 28.6 mg/L 9 ECETOC Aquatic Toxicity, EAT DeGraeve ea 80 2016/02/08