有害性クラス判定の根拠データ 13138459

化学物質有害性情報データベース物質情報

CAS 登録番号 CAS RN^® ： 13138459
官報公示整理番号　METI No. ： 1-514
物質名 test material ：硝酸ニッケル（ＩＩ）　／Nickel nitrate
水溶解度 water solubility ： 177600mg/L (推計値 estimated)
LogKow ： -0.61 (推計値 estimated)
備考 remarks ：

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【注意事項】
* 化学物質有害性情報データベース情報更新日が2019年9月以前はRead-acrossデータでも○としていないので、毒性値の取り扱いには注意が必要である。

生物種	学名	影響内容	エンドポイント	暴露期間(値)	暴露期間(単位)	毒性値	毒性値(単位)	Read-across *	設定濃度	情報源	著者	タイトル	記載誌	発行年	情報更新日
藻類	Navicula pelliculosa	growth rate	EC30	3	days	0.8	μmol/L			12 ECHA Information on Registered Substances	Nagai T, De Schamphelaere KA.	The effect of binary mixtures of zinc, copper, cadmium, and nickel on the growth of the freshwater diatom Navicula pelliculosa and comparison with mixture toxicity model predictions.	Environ Toxicol Chem. 2016 Nov;35(11)		2021/03/02
藻類	Navicula pelliculosa	growth rate	EC10/4	3	days	0.15	μmol/L			12 ECHA Information on Registered Substances	Nagai T, De Schamphelaere KA.	The effect of binary mixtures of zinc, copper, cadmium, and nickel on the growth of the freshwater diatom Navicula pelliculosa and comparison with mixture toxicity model predictions.	Environ Toxicol Chem. 2016 Nov;35(11)		2021/03/02
藻類	Scenedesmus quadricauda		toxic threshold	7	days	1.3	mg/L			12 ECHA Information on Registered Substances	Bringmann G. and R. Kuhn	Comparison of the toxicity thresholds of water pollutants to bacteria, algae, and protozoa in the cell multiplication inhibition test	Water Res. 14		2021/03/02
藻類	Chlorella vulgaris	growth rate	EC15	12	days	1.9	mg/L			12 ECHA Information on Registered Substances	Rugnini L, Costa G, Congestri R, Bruno L	Testing of two different strains of green microalgae for Cu and Ni removal from aqueous media	Science of the Total Environment 601–602		2021/03/02
藻類	Chlorella vulgaris	growth rate	EC22	12	days	5.7	mg/L			12 ECHA Information on Registered Substances	Rugnini L, Costa G, Congestri R, Bruno L	Testing of two different strains of green microalgae for Cu and Ni removal from aqueous media	Science of the Total Environment 601–602		2021/03/02
藻類	Chlorella vulgaris	growth rate	EC25	12	days	11.4	mg/L			12 ECHA Information on Registered Substances	Rugnini L, Costa G, Congestri R, Bruno L	Testing of two different strains of green microalgae for Cu and Ni removal from aqueous media	Science of the Total Environment 601–602		2021/03/02
藻類	Scenedesmus quadricauda	not reported	"Toxic"			>=1.3	mg/L			12 ECHA Information on Registered Substances		other company data			2021/03/02
藻類	Navicula pelliculosa	growth rate	EC70	3	days	1.11	μmol/L			12 ECHA Information on Registered Substances	Nagai T, De Schamphelaere KA.	The effect of binary mixtures of zinc, copper, cadmium, and nickel on the growth of the freshwater diatom Navicula pelliculosa and comparison with mixture toxicity model predictions.	Environ Toxicol Chem. 2016 Nov;35(11)		2021/03/02
藻類	Navicula pelliculosa	growth rate	EC10/2	3	days	0.31	μmol/L			12 ECHA Information on Registered Substances	Nagai T, De Schamphelaere KA.	The effect of binary mixtures of zinc, copper, cadmium, and nickel on the growth of the freshwater diatom Navicula pelliculosa and comparison with mixture toxicity model predictions.	Environ Toxicol Chem. 2016 Nov;35(11)		2021/03/02
藻類	Dunaliella tertiolecta	Average Yield	IC20	72	hours	13397.9	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
藻類	Dunaliella tertiolecta	Average Area Under Growth Curve	IC20	72	hours	13800.9	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
藻類	Dunaliella tertiolecta	Average Specific Growth Rate	IC20	72	hours	27481.8	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
藻類	Navicula pelliculosa	Population		14	days	100	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Fezy,J.S., D.F. Spencer, and R.W. Greene	The Effect of Nickel on the Growth of the Freshwater Diatom Navicula pelliculosa	Environ. Pollut.20(2): 131-137	1979	2016/03/25
藻類	Anabaena flos-aquae	Population		14	days	301	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Spencer,D.F., and R.W. Greene	Effects of Nickel on Seven Species of Freshwater Algae	Environ. Pollut. A.25(4): 241-247	1981	2016/03/25
藻類	Navicula pelliculosa	Population		7	days	100	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Fezy,J.S., D.F. Spencer, and R.W. Greene	The Effect of Nickel on the Growth of the Freshwater Diatom Navicula pelliculosa	Environ. Pollut.20(2): 131-137	1979	2016/03/25
藻類	Chlorella vulgaris	Population	NOEC			6.9	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	De Jong,L.E.D.	Tolerance of Chlorella vulgaris for Metallic and Non-Metallic Ions	Antonie van Leeuwenhoek (Gedrukt)31:301-313	1965	2016/03/25
藻類	Chlorella vulgaris	Population	LOEC			17	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	De Jong,L.E.D.	Tolerance of Chlorella vulgaris for Metallic and Non-Metallic Ions	Antonie van Leeuwenhoek (Gedrukt)31:301-313	1965	2016/03/25
藻類	Anabaena flos-aquae	Population		14	days	602	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Spencer,D.F., and R.W. Greene	Effects of Nickel on Seven Species of Freshwater Algae	Environ. Pollut. A.25(4): 241-247	1981	2016/03/25
藻類	Chlorella vulgaris	Population	LOEC	121.76	days	17	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	De Jong,L.E.D.	Tolerance of Chlorella vulgaris for Metallic and Non-Metallic Ions	Antonie van Leeuwenhoek (Gedrukt)31:301-313	1965	2017/03/23
藻類	Chlorella vulgaris	Population	NOEC	121.76	days	6.9	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	De Jong,L.E.D.	Tolerance of Chlorella vulgaris for Metallic and Non-Metallic Ions	Antonie van Leeuwenhoek (Gedrukt)31:301-313	1965	2017/03/23
藻類	Chlorella sp.	growth rate	EC50	72	hours	663	μg/L			12 ECHA Information on Registered Substances	Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R	Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters	Environmental Toxicology and Chemistry. 37 (10)		2021/03/02
藻類	Chlorella sp.	growth rate	EC50	72	hours	826	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
藻類	Scenedesmus quadricauda	growth rate	EC50	12	days	0.6	mg/L			12 ECHA Information on Registered Substances	Fargasova, A.	Interactive effect of manganese, molybdenum, nickel, copper I and II, and vanadium on the freshwater alga Scenedesmus quadricauda.	Bull. Environ. Contam. Toxicol. 67		2021/03/02
藻類	Scenedesmus quadricauda	Chlorophyll-b inhibition	EC50	12	days	0.39	mg/L			12 ECHA Information on Registered Substances	Fargasova, A., A. Bumbalova, and E. Havranek.	Ecotoxicological effect and uptake of metals (Cu+, Cu2+, Mn2+, Mo6+, Ni2+, V5+) in freshwater alga Scenedesmus quadricauda.	Chemosphere. 38(5)		2021/03/02
藻類	Scenedesmus quadricauda	Chlorophyll-a inhibition	EC50	12	days	0.57	mg/L			12 ECHA Information on Registered Substances	Fargasova, A., A. Bumbalova, and E. Havranek.	Ecotoxicological effect and uptake of metals (Cu+, Cu2+, Mn2+, Mo6+, Ni2+, V5+) in freshwater alga Scenedesmus quadricauda.	Chemosphere. 38(5)		2021/03/02
藻類	Navicula pelliculosa	growth rate	EC50	3	days	0.94	μmol/L			12 ECHA Information on Registered Substances	Nagai T, De Schamphelaere KA.	The effect of binary mixtures of zinc, copper, cadmium, and nickel on the growth of the freshwater diatom Navicula pelliculosa and comparison with mixture toxicity model predictions.	Environ Toxicol Chem. 2016 Nov;35(11)		2021/03/02
藻類	Chlorella sp.	growth rate	EC50	72	hours	1430	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
藻類	Scenedesmus quadricauda	Total Chlorophyll inhibition	EC50	12	days	0.44	mg/L			12 ECHA Information on Registered Substances	Fargasova, A., A. Bumbalova, and E. Havranek.	Ecotoxicological effect and uptake of metals (Cu+, Cu2+, Mn2+, Mo6+, Ni2+, V5+) in freshwater alga Scenedesmus quadricauda.	Chemosphere. 38(5)		2021/03/02
藻類	Chlorella sp.	growth rate	EC50	72	hours	282	μg/L			12 ECHA Information on Registered Substances	Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R	Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters	Environmental Toxicology and Chemistry. 37 (10)		2021/03/02
藻類	Chlorella pyrenoidosa	growth rate	EC50	24	hours	0.41	mg/L			12 ECHA Information on Registered Substances	Lin, K.C., Y.L. Lee, and C.Y. Chen	Metal toxicity to Chlorella pyrenoidosa assessed by a short-term continuous test	Journal of Hazardous Materials 142		2021/03/02
藻類	Chlorella sp.	growth rate	EC50	72	hours	434	μg/L			12 ECHA Information on Registered Substances	Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R	Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters	Environmental Toxicology and Chemistry. 37 (10)		2021/03/02
藻類	Chlorella sp.	growth rate	EC50	72	hours	2413	μg/L			12 ECHA Information on Registered Substances	Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R	Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters	Environmental Toxicology and Chemistry. 37 (10)		2021/03/02
藻類	Scenedesmus acutus	growth rate	EC50	96	hours	33.3	mg/L			12 ECHA Information on Registered Substances	Azeez, P.A. and D.K. Banerjee.	Nickel uptake and toxicity in cyanobacteria.	Toxicological and environmental chemistry		2021/03/02
藻類	Scenedesmus acutus	growth rate	EC50	120	hours	16.5	mg/L			12 ECHA Information on Registered Substances	Azeez, P.A. and D.K. Banerjee.	Nickel uptake and toxicity in cyanobacteria.	Toxicological and environmental chemistry		2021/03/02
藻類	Scenedesmus acutus	growth rate	EC50	144	hours	9.07	mg/L			12 ECHA Information on Registered Substances	Azeez, P.A. and D.K. Banerjee.	Nickel uptake and toxicity in cyanobacteria.	Toxicological and environmental chemistry		2021/03/02
藻類	Scenedesmus acutus	growth rate	EC50	168	hours	8.34	mg/L			12 ECHA Information on Registered Substances	Azeez, P.A. and D.K. Banerjee.	Nickel uptake and toxicity in cyanobacteria.	Toxicological and environmental chemistry		2021/03/02
藻類	Scenedesmus quadricauda	growth rate	EC50	12	days	0.58	mg/L			12 ECHA Information on Registered Substances	Fargasova, A., A. Bumbalova, and E. Havranek.	Ecotoxicological effect and uptake of metals (Cu+, Cu2+, Mn2+, Mo6+, Ni2+, V5+) in freshwater alga Scenedesmus quadricauda.	Chemosphere. 38(5)		2021/03/02
藻類	Chlorella sp.	growth rate	EC50	72	hours	853	μg/L			12 ECHA Information on Registered Substances	Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R	Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters	Environmental Toxicology and Chemistry. 37 (10)		2021/03/02
藻類	Anabaena flos-aquae	growth rate	LOEC	14	days	600	μg/L			12 ECHA Information on Registered Substances	Spencer, D.F. and R.W. Greene.	Effects of nickel on seven species of freshwater algae.	Environ. Pollut. (Series A). 25(4)		2021/03/02
藻類	Anabaena flos-aquae	growth rate	NOEC	14	days	300	μg/L			12 ECHA Information on Registered Substances	Spencer, D.F. and R.W. Greene.	Effects of nickel on seven species of freshwater algae.	Environ. Pollut. (Series A). 25(4)		2021/03/02
藻類	Chlorella sp.	growth rate	EC10	72	hours	896	μg/L			12 ECHA Information on Registered Substances	Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R	Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters	Environmental Toxicology and Chemistry. 37 (10)		2021/03/02
藻類	Dunaliella tertiolecta	Average Yield, Average Area Under Growth Cu	NOEC	72	hours	5476.8	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
藻類	Dunaliella tertiolecta	Average Yield, Average Area Under Growth Cu	LOEC	72	hours	11551.3	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
藻類	Chlorella sp.	growth rate	EC10	72	hours	90.5	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
藻類	Chlorella sp.	growth rate	EC10	72	hours	64.7	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
藻類	Skeletonema costatum	Average Specific Growth Rate	EC10	72	hours	661.3	μg/L			12 ECHA Information on Registered Substances	DeForest DK, Schlekat CE.	Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.	Integr Environ Assess Manag. 2013 Oct;9(4)		2021/03/02
藻類	Chlorella sp.	growth rate	LOEC	72	hours	97.7	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
藻類	Chlorella sp.	growth rate	NOEC	72	hours	98.2	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
藻類	Skeletonema costatum	Average Specific Growth Rate	EC10	72	hours	190.6	μg/L			12 ECHA Information on Registered Substances	DeForest DK, Schlekat CE.	Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.	Integr Environ Assess Manag. 2013 Oct;9(4)		2021/03/02
藻類	Chlorella sp.	growth rate	NOEC	72	hours	<97.7	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
藻類	Chlorella sp.	growth rate	LOEC	72	hours	168	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
藻類	Skeletonema costatum	Average Specific Growth Rate	EC10	72	hours	265.4	μg/L			12 ECHA Information on Registered Substances	DeForest DK, Schlekat CE.	Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.	Integr Environ Assess Manag. 2013 Oct;9(4)		2021/03/02
藻類	Scenedesmus quadricauda	nitrate reductase activity, alkaline phosph	NOEC	15	days	<1.1	μM			12 ECHA Information on Registered Substances		publication			2021/03/02
藻類	Chlorella vulgaris	other: nitrate reductase activity	LOEC	15	days	3.2	μmol/L			12 ECHA Information on Registered Substances		publication			2021/03/02
藻類	Chlorella vulgaris	other: nitrate reductase activity, alkaline	NOEC	15	days	<3.2	μmol/L			12 ECHA Information on Registered Substances		publication			2021/03/02
藻類	Skeletonema costatum	Average Specific Growth Rate	EC10	72	hours	773.4	μg/L			12 ECHA Information on Registered Substances	DeForest DK, Schlekat CE.	Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.	Integr Environ Assess Manag. 2013 Oct;9(4)		2021/03/02
藻類	Navicula pelliculosa	growth rate	EC10	3	days	0.61	μmol/L			12 ECHA Information on Registered Substances	Nagai T, De Schamphelaere KA.	The effect of binary mixtures of zinc, copper, cadmium, and nickel on the growth of the freshwater diatom Navicula pelliculosa and comparison with mixture toxicity model predictions.	Environ Toxicol Chem. 2016 Nov;35(11)		2021/03/02
藻類	Chlorella sp.	growth rate	EC10	72	hours	148	μg/L			12 ECHA Information on Registered Substances	Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R	Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters	Environmental Toxicology and Chemistry. 37 (10)		2021/03/02
藻類	Chlorella sp.	growth rate	EC10	72	hours	59	μg/L			12 ECHA Information on Registered Substances	Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R	Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters	Environmental Toxicology and Chemistry. 37 (10)		2021/03/02
藻類	Scenedesmus quadricauda	nitrate reductase activity, alkaline phosph	LOEC	15	days	1.1	μM			12 ECHA Information on Registered Substances		publication			2021/03/02
藻類	Chlorella vulgaris	Growth	LOEC		months	17	μg/L			16 ECOTOX	De Jong,L.E.D.	Tolerance of Chlorella vulgaris for Metallic and Non-Metallic Ions	Antonie van Leeuwenhoek (Gedrukt)31		2020/11/12
藻類	Anabaena cylindrica	growth rate	NOEC	14	days	600	μg/L			12 ECHA Information on Registered Substances	Spencer, D.F. and R.W. Greene.	Effects of nickel on seven species of freshwater algae.	Environ. Pollut. (Series A). 25(4)		2021/03/02
藻類	Anabaena cylindrica	growth rate	LOEC	14	days	>600	μg/L			12 ECHA Information on Registered Substances	Spencer, D.F. and R.W. Greene.	Effects of nickel on seven species of freshwater algae.	Environ. Pollut. (Series A). 25(4)		2021/03/02
藻類	Chlorella sp.	growth rate	EC10	72	hours	122	μg/L			12 ECHA Information on Registered Substances	Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R	Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters	Environmental Toxicology and Chemistry. 37 (10)		2021/03/02
藻類	Chlorella vulgaris	Growth	NOEC		months	6.9	μg/L			16 ECOTOX	De Jong,L.E.D.	Tolerance of Chlorella vulgaris for Metallic and Non-Metallic Ions	Antonie van Leeuwenhoek (Gedrukt)31		2020/11/12
藻類	Chlorella sp.	growth rate	EC10	72	hours	278	μg/L			12 ECHA Information on Registered Substances	Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R	Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters	Environmental Toxicology and Chemistry. 37 (10)		2021/03/02
藻類	Scenedesmus quadricauda	growth rate	LOEC	14	days	100	μg/L			12 ECHA Information on Registered Substances	Spencer, D.F. and R.W. Greene.	Effects of nickel on seven species of freshwater algae.	Environ. Pollut. (Series A). 25(4)		2021/03/02
藻類	Navicula pelliculosa	growth rate	LOEC	14	days	<100	μg/L			12 ECHA Information on Registered Substances	Fezy, J.S., D.F. Spencer, and R.W. Greene.	The effect of nickel on the growth of the freshwater diatom Navicula pelliculosa.	Environ. Pollut. 20(3)		2021/03/02
藻類	Dunaliella tertiolecta	Average Yield	IC10	72	hours	8585.6	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
藻類	Dunaliella tertiolecta	Average Area Under Growth Curve	IC10	72	hours	8574.1	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
藻類	Skeletonema costatum	Average Specific Growth Rate	EC10	72	hours	122.7	μg/L			12 ECHA Information on Registered Substances	DeForest DK, Schlekat CE.	Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.	Integr Environ Assess Manag. 2013 Oct;9(4)		2021/03/02
藻類	Dunaliella tertiolecta	Average Specific Growth Rate	IC10	72	hours	17891.1	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
藻類	Scenedesmus quadricauda	growth rate	LOEC	14	days	<100	μg/L			12 ECHA Information on Registered Substances	Spencer, D.F. and R.W. Greene.	Effects of nickel on seven species of freshwater algae.	Environ. Pollut. (Series A). 25(4)		2021/03/02
藻類	Navicula pelliculosa	growth rate	LOEC	14	days	100	μg/L			12 ECHA Information on Registered Substances	Fezy, J.S., D.F. Spencer, and R.W. Greene.	The effect of nickel on the growth of the freshwater diatom Navicula pelliculosa.	Environ. Pollut. 20(3)		2021/03/02
甲殻類	Chironomus riparius	Mortality	LC50	48	hours	150000	μg/L			16 ECOTOX	Powlesland,C., and J. George	Acute and Chronic Toxicity of Nickel to Larvae of Chironomus riparis (Meigen)	Environ. Pollut. A.42(1)		2020/11/12
甲殻類	Chironomus riparius	Mortality	LC50	48	hours	184000	μg/L			16 ECOTOX	Powlesland,C., and J. George	Acute and Chronic Toxicity of Nickel to Larvae of Chironomus riparis (Meigen)	Environ. Pollut. A.42(1)		2020/11/12
甲殻類	Chironomus dilutus	Population//Abundance	NOEC	21	days	91.33	μg/L		3.80 ug/L / 91.33 ug/L	16 ECOTOX	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462)		2020/11/12
甲殻類	Chironomus riparius	Mortality	LC50	48	hours	81300	μg/L			16 ECOTOX	Powlesland,C., and J. George	Acute and Chronic Toxicity of Nickel to Larvae of Chironomus riparis (Meigen)	Environ. Pollut. A.42(1)		2020/11/12
甲殻類	Chironomus riparius	Mortality	LC50	48	hours	72400	μg/L			16 ECOTOX	Powlesland,C., and J. George	Acute and Chronic Toxicity of Nickel to Larvae of Chironomus riparis (Meigen)	Environ. Pollut. A.42(1)		2020/11/12
甲殻類	Chironomus riparius	Mortality	LC50	48	hours	174000	μg/L			16 ECOTOX	Powlesland,C., and J. George	Acute and Chronic Toxicity of Nickel to Larvae of Chironomus riparis (Meigen)	Environ. Pollut. A.42(1)		2020/11/12
甲殻類	Chironomus riparius	Mortality	NR-LETH	15	days	13900	μg/L			16 ECOTOX	Powlesland,C., and J. George	Acute and Chronic Toxicity of Nickel to Larvae of Chironomus riparis (Meigen)	Environ. Pollut. A.42(1)		2020/11/12
甲殻類	Chironomus riparius	Mortality	LC50	48	hours	84900	μg/L			16 ECOTOX	Powlesland,C., and J. George	Acute and Chronic Toxicity of Nickel to Larvae of Chironomus riparis (Meigen)	Environ. Pollut. A.42(1)		2020/11/12
甲殻類	Daphnia magna	Mortality	LD50	1	days	6000	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Tomasik,P., C.H.D. Magadza, S. Mhizha, and A. Chirume	The Metal-Metal Interactions in Biological Systems. Part III. Daphnia magna	Water Air Soil Pollut.82:695-711	1995	2016/03/25
甲殻類	Ceriodaphnia dubia	Mortality		7	days	3.8	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Kszos,L.A., A.J. Stewart, and P.A. Taylor	An Evaluation of Nickel Toxicity to Ceriodaphnia dubia and Daphnia magna in a Contaminated Stream and in Laboratory Tests	Environ. Toxicol. Chem.11(7): 1001-1012	1992	2016/03/25
甲殻類	Ceriodaphnia dubia	Reproduction		7	days	3.8	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Kszos,L.A., A.J. Stewart, and P.A. Taylor	An Evaluation of Nickel Toxicity to Ceriodaphnia dubia and Daphnia magna in a Contaminated Stream and in Laboratory Tests	Environ. Toxicol. Chem.11(7): 1001-1012	1992	2016/03/25
甲殻類	Daphnia magna	Mortality	LD50	1	days	11000	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Tomasik,P., C.H.D. Magadza, S. Mhizha, and A. Chirume	The Metal-Metal Interactions in Biological Systems. Part III. Daphnia magna	Water Air Soil Pollut.82:695-711	1995	2016/03/25
甲殻類	Daphnia magna	Mortality	LC50	2	days	915	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Call,D.J., L.T. Brooke, N. Ahmad, and J.E. Richter	Toxicity and Metabolism Studies with EPA (Environmental Protection Agency) Priority Pollutants and Related Chemicals in Freshwater Organisms	EPA 600/3-83-095, U.S.EPA, Duluth, MN:120 p.	1983	2016/03/25
甲殻類	Ceriodaphnia dubia	Mortality		7	days	7.5	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Kszos,L.A., A.J. Stewart, and P.A. Taylor	An Evaluation of Nickel Toxicity to Ceriodaphnia dubia and Daphnia magna in a Contaminated Stream and in Laboratory Tests	Environ. Toxicol. Chem.11(7): 1001-1012	1992	2016/03/25
甲殻類	Ceriodaphnia dubia	Mortality		7	days	7.5	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Kszos,L.A., A.J. Stewart, and P.A. Taylor	An Evaluation of Nickel Toxicity to Ceriodaphnia dubia and Daphnia magna in a Contaminated Stream and in Laboratory Tests	Environ. Toxicol. Chem.11(7): 1001-1012	1992	2017/03/15
甲殻類	Daphnia magna	Mortality	LC50	2	days	915	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Call,D.J., L.T. Brooke, N. Ahmad, and J.E. Richter	Toxicity and Metabolism Studies with EPA (Environmental Protection Agency) Priority Pollutants and Related Chemicals in Freshwater Organisms	EPA 600/3-83-095, U.S.EPA, Duluth, MN:120 p.	1983	2017/03/15
甲殻類	Daphnia magna	immobilisation	EC50	48	hours	3.85	mg/L			12 ECHA Information on Registered Substances	Kim D, Chae Y, An Y-J	Mixture Toxicity of Nickel and Microplastics with Different Functional Groups on Daphnia magna	Environmental Science and Technology. 51		2021/03/02
甲殻類	Daphnia magna	mortality	LC20	48	hours	1036.7	μg/L			12 ECHA Information on Registered Substances	Lari E, Gauthier P, Mohaddes E, Pyle GG	Interactive toxicity of Ni, Zn, Cu, and Cd on Daphnia magna at lethal and sub-lethal concentrations	Journal of Hazardous Materials 334		2021/03/02
甲殻類	Daphnia magna	feeding inhibition	EC50	24	hours	2.41	mg/L	○		12 ECHA Information on Registered Substances		publication			2021/03/02
甲殻類	Daphnia magna	mortality	LC50	48	hours	1502.5	μg/L			12 ECHA Information on Registered Substances	Lari E, Gauthier P, Mohaddes E, Pyle GG	Interactive toxicity of Ni, Zn, Cu, and Cd on Daphnia magna at lethal and sub-lethal concentrations	Journal of Hazardous Materials 334		2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	96	hours	27.6	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	296	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC10	48	hours	86.8	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC10	48	hours	88.9	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	598	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC10	48	hours	125	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	96	hours	214.1	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC10	48	hours	122	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	94.3	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	13	μg/L			12 ECHA Information on Registered Substances	Schubauer-Berigan, M.K., J.R. Dierkes, P.D. Monson, and G.T. Ankley	pH-Dependent toxicity of Cd, Cu, Ni, Pb and Zn to Ceriodaphnia dubia, Pimephales Promelas, Hyalella azteca and Lumbriculus variegates	Environmental Toxicology and Chemistry. 12		2021/03/02
甲殻類	Daphnia magna	mortality	LC50	24	hours	10.9	mg/L			12 ECHA Information on Registered Substances	Khangarot, B.S. and P.K. Ray	Investigation of correlation between physicochemical properties of metals and their toxicity to the water flea Daphnia magna Straus	Ecotoxicology and Environmental Safety. 18		2021/03/02
甲殻類	Daphnia magna	immobilization	EC50	48	hours	>=0.86～<=6.3	mg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	96	hours	82.1	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	593	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna	mortality	LC50	48	hours	510	μg/L			12 ECHA Information on Registered Substances	Biesinger, K.E. and G.M. Christensen	Effects of various metals on survival, growth, reproduction, and metabolism of Daphnia magna	Journal of Fisheries Research Board of Canada. 29(12)		2021/03/02
甲殻類	Daphnia magna	mortality	NOEC	48	hours	25	mg/L			12 ECHA Information on Registered Substances	Bozich J, Hang M, Hamers R, Klaper R	Core chemistry influences the toxicity of multicomponent metal oxide nanomaterials, lithium nickel manganese cobalt oxide, and lithium cobalt oxide to Daphnia magna	Environ Toxicol Chem; 36(9)		2021/03/02
甲殻類	Daphnia pulex	mortality	LC50	48	hours	7.5	μmol/L			12 ECHA Information on Registered Substances	Leonard EM, Wood CM	Acute toxicity, critical body residues, Michaelis-Menten analysis of bioaccumulation, and ionoregulatory disturbance in response to waterborne nickel in four invertebrates: Chironomus riparius, Lymnaea stagnalis, Lumbriculus variegatus and Daphnia pulex	Comparative Biochemistry and Physiology, Part C 158		2021/03/02
甲殻類	Daphnia magna		LC50	48	hours	627	mg/L			12 ECHA Information on Registered Substances		government document			2021/03/02
甲殻類	Daphnia magna		LC50	48	hours	645	mg/L			12 ECHA Information on Registered Substances		government document			2021/03/02
甲殻類	Daphnia magna		LC50	48	hours	1800	mg/L			12 ECHA Information on Registered Substances		government document			2021/03/02
甲殻類	Daphnia magna		LC50	48	hours	1810	mg/L			12 ECHA Information on Registered Substances		government document			2021/03/02
甲殻類	Daphnia magna	immobilization	EC50	48	hours	70.8	μM			12 ECHA Information on Registered Substances		publication			2021/03/02
甲殻類	Daphnia magna	mortality	LC75	48	hours	2150	μg/L	○		12 ECHA Information on Registered Substances		publication			2021/03/02
甲殻類	Daphnia magna	mobility	EC50	24	hours	11.77	mg/L			12 ECHA Information on Registered Substances	Sivula L, Vehniainen E-R, Karjalainen AK, Kukkonen JVK	Toxicity of biomining effluents to Daphnia magna: Acute toxicity and transcriptomic biomarkers	Chemosphere, 210		2021/03/02
甲殻類	Daphnia magna		LC50	96	hours	3.2	mg/L			12 ECHA Information on Registered Substances	Ewell, W.S., J.W. Gorsuch, R.O. Kringle, K.A. Robillard, and R.C. Spiegel	Simultaneous evaluation of the acute effects of chemicals on seven aquatic species	Environmental Toxicology and Chemistry. 5		2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	96	hours	74.4	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	297	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	96	hours	133.1	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna	mortality	LC50	48	hours	7.59	mg/L			12 ECHA Information on Registered Substances	Khangarot, B.S. and P.K. Ray	Investigation of correlation between physicochemical properties of metals and their toxicity to the water flea Daphnia magna Straus	Ecotoxicology and Environmental Safety. 18		2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	96	hours	94.3	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia pulex	mortality	LC50	48	hours	26	μmol/L			12 ECHA Information on Registered Substances	Leonard EM, Wood CM	Acute toxicity, critical body residues, Michaelis-Menten analysis of bioaccumulation, and ionoregulatory disturbance in response to waterborne nickel in four invertebrates: Chironomus riparius, Lymnaea stagnalis, Lumbriculus variegatus and Daphnia pulex	Comparative Biochemistry and Physiology, Part C 158		2021/03/02
甲殻類	Daphnia magna		NOEC	48	hours	1.8	mg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna	mortality	EC50	48	hours	6.68	mg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	96	hours	266.3	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	96	hours	202.3	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	96	hours	111.1	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna	mortality	LC50	48	hours	0.915	mg/L			12 ECHA Information on Registered Substances	Call, D.J., L.T. Brooke, N. Ahmad, and J.E. Richter.	Toxicity and metabolism studies with EPA priority pollutants and related chemicals in freshwater organisms.	PB83-263665/EPA-600/3-83-095. National Technical Information Service (NTIS). Springfield, VA.		2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	96	hours	87.5	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	96	hours	107.3	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna	mortality	LC50	48	hours	1120	μg/L			12 ECHA Information on Registered Substances	Biesinger, K.E. and G.M. Christensen	Effects of various metals on survival, growth, reproduction, and metabolism of Daphnia magna	Journal of Fisheries Research Board of Canada. 29(12)		2021/03/02
甲殻類	Daphnia magna		EC50	48	hours	9.48	mg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	111.1	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia pulicaria	mortality	LC50	48	hours	1813	μg/L			12 ECHA Information on Registered Substances	Lind, D., K. Alto, and S. Chatterton.	Regional Copper-Nickel Study: Aquatic Toxicology Study.	Minnesota Environmental Quality Board		2021/03/02
甲殻類	Daphnia magna		LC50	24	hours	10.1	mg/L			12 ECHA Information on Registered Substances	Van Sprang, P.A. and C.R. Janssen.	Toxicity identification of metals: Development of toxicity identification fingerprints.	Environmental Toxicology and Chemistry. 20(11)		2021/03/02
甲殻類	Daphnia magna	feeding inhibition	EC50	24	hours	2.74	mg/L	○		12 ECHA Information on Registered Substances		publication			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	27.6	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna		NOEC	48	hours	1	mg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia pulicaria	mortality	LC50	48	hours	2171	μg/L			12 ECHA Information on Registered Substances	Lind, D., K. Alto, and S. Chatterton.	Regional Copper-Nickel Study: Aquatic Toxicology Study.	Minnesota Environmental Quality Board		2021/03/02
甲殻類	Daphnia pulicaria	mortality	LC50	48	hours	3757	μg/L			12 ECHA Information on Registered Substances	Lind, D., K. Alto, and S. Chatterton.	Regional Copper-Nickel Study: Aquatic Toxicology Study.	Minnesota Environmental Quality Board		2021/03/02
甲殻類	Daphnia pulicaria	mortality	LC50	48	hours	3414	μg/L			12 ECHA Information on Registered Substances	Lind, D., K. Alto, and S. Chatterton.	Regional Copper-Nickel Study: Aquatic Toxicology Study.	Minnesota Environmental Quality Board		2021/03/02
甲殻類	Daphnia pulicaria	mortality	LC50	48	hours	2325	μg/L			12 ECHA Information on Registered Substances	Lind, D., K. Alto, and S. Chatterton.	Regional Copper-Nickel Study: Aquatic Toxicology Study.	Minnesota Environmental Quality Board		2021/03/02
甲殻類	Daphnia pulicaria	mortality	LC50	48	hours	3014	μg/L			12 ECHA Information on Registered Substances	Lind, D., K. Alto, and S. Chatterton.	Regional Copper-Nickel Study: Aquatic Toxicology Study.	Minnesota Environmental Quality Board		2021/03/02
甲殻類	Daphnia pulicaria	mortality	LC50	48	hours	697	μg/L			12 ECHA Information on Registered Substances	Lind, D., K. Alto, and S. Chatterton.	Regional Copper-Nickel Study: Aquatic Toxicology Study.	Minnesota Environmental Quality Board		2021/03/02
甲殻類	Daphnia pulicaria	mortality	LC50	48	hours	1034	μg/L			12 ECHA Information on Registered Substances	Lind, D., K. Alto, and S. Chatterton.	Regional Copper-Nickel Study: Aquatic Toxicology Study.	Minnesota Environmental Quality Board		2021/03/02
甲殻類	Daphnia pulicaria	mortality	LC50	48	hours	1836	μg/L			12 ECHA Information on Registered Substances	Lind, D., K. Alto, and S. Chatterton.	Regional Copper-Nickel Study: Aquatic Toxicology Study.	Minnesota Environmental Quality Board		2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	74.4	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	87.5	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	276	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna		LC50	48	hours	1940	mg/L			12 ECHA Information on Registered Substances		government document			2021/03/02
甲殻類	Daphnia magna		LC50	48	hours	2360	mg/L			12 ECHA Information on Registered Substances		government document			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	82.1	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna		LC50	48	hours	2340	mg/L			12 ECHA Information on Registered Substances		government document			2021/03/02
甲殻類	Daphnia magna	mobility	LC50	48	hours	7.36	mg/L	○		12 ECHA Information on Registered Substances		publication			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	140	μg/L			12 ECHA Information on Registered Substances	Schubauer-Berigan, M.K., J.R. Dierkes, P.D. Monson, and G.T. Ankley	pH-Dependent toxicity of Cd, Cu, Ni, Pb and Zn to Ceriodaphnia dubia, Pimephales Promelas, Hyalella azteca and Lumbriculus variegates	Environmental Toxicology and Chemistry. 12		2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	>200	μg/L			12 ECHA Information on Registered Substances	Schubauer-Berigan, M.K., J.R. Dierkes, P.D. Monson, and G.T. Ankley	pH-Dependent toxicity of Cd, Cu, Ni, Pb and Zn to Ceriodaphnia dubia, Pimephales Promelas, Hyalella azteca and Lumbriculus variegates	Environmental Toxicology and Chemistry. 12		2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	133.1	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	121.6	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia pulicaria	mortality	LC50	48	hours	3316	μg/L			12 ECHA Information on Registered Substances	Lind, D., K. Alto, and S. Chatterton.	Regional Copper-Nickel Study: Aquatic Toxicology Study.	Minnesota Environmental Quality Board		2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	266.3	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia pulicaria	mortality	LC50	48	hours	2182	μg/L			12 ECHA Information on Registered Substances	Lind, D., K. Alto, and S. Chatterton.	Regional Copper-Nickel Study: Aquatic Toxicology Study.	Minnesota Environmental Quality Board		2021/03/02
甲殻類	Daphnia pulicaria	mortality	LC50	48	hours	1141	μg/L			12 ECHA Information on Registered Substances	Lind, D., K. Alto, and S. Chatterton.	Regional Copper-Nickel Study: Aquatic Toxicology Study.	Minnesota Environmental Quality Board		2021/03/02
甲殻類	Daphnia magna		LC50	48	hours	1920	mg/L			12 ECHA Information on Registered Substances		government document			2021/03/02
甲殻類	Daphnia pulex	mortality	LC50	48	hours	912.332	μg/L			12 ECHA Information on Registered Substances	Jindal, R. and A. Verma	Heavy Metal Toxicity to Daphnia pulex	Indian J. Environ. Health. 32(3)		2021/03/02
甲殻類	Daphnia magna	mortality	LC50			1068	μg/L			12 ECHA Information on Registered Substances	Pane, E.F., Smith, C., McGeer, J.C., and C.M. Wood.	Mechanisms of Acute and Chronic Waterborne Nickel Toxicity in the Freshwater Cladoceran, Daphnia magna	Environmental Science and Technology. 37		2021/03/02
甲殻類	Daphnia magna		LC50	48	hours	4970	mg/L			12 ECHA Information on Registered Substances		government document			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	202.3	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	214.1	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna	Mortality	LD50	24	hours	11	mg/L			16 ECOTOX	Tomasik,P., C.H.D. Magadza, S. Mhizha, and A. Chirume	The Metal-Metal Interactions in Biological Systems. Part III. Daphnia magna	Water Air Soil Pollut.82		2020/11/12
甲殻類	Daphnia magna	Mortality	LD50	24	hours	6	mg/L			16 ECOTOX	Tomasik,P., C.H.D. Magadza, S. Mhizha, and A. Chirume	The Metal-Metal Interactions in Biological Systems. Part III. Daphnia magna	Water Air Soil Pollut.82		2020/11/12
甲殻類	Daphnia magna	Mortality	LC50	48	hours	915	μg/L			16 ECOTOX	Call,D.J., L.T. Brooke, N. Ahmad, and J.E. Richter	Toxicity and Metabolism Studies with EPA (Environmental Protection Agency) Priority Pollutants and Related Chemicals in Freshwater Organisms	EPA 600/3-83-095, U.S.EPA, Duluth, MN		2020/11/12
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	105.1	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC50	48	hours	107.3	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna	mortality	LC50			11	mg/L			12 ECHA Information on Registered Substances		other company data			2021/03/02
甲殻類	Daphnia magna		EC50	48	hours	>100	mg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna		LC50	48	hours	4960	mg/L			12 ECHA Information on Registered Substances		government document			2021/03/02
甲殻類	Daphnia magna	Mortality	LC50	48	hours	0.915	mgNi/L [measured]			8 NITE 化学物質の初期リスク評価書	Call, D.J., Brooke, L.T. Ahmad, N. and Richter, J.E.	Toxicity and metabolism studies with EPA priority pollutants and related chemicals in freshwater organisms.	EPA 600/3-83-095, U.S.EPA, Duluth, MN		2021/04/06
甲殻類	Daphnia pulicaria	mortality	LC50	48	hours	3156	μg/L			12 ECHA Information on Registered Substances	Lind, D., K. Alto, and S. Chatterton.	Regional Copper-Nickel Study: Aquatic Toxicology Study.	Minnesota Environmental Quality Board		2021/03/02
甲殻類	Daphnia pulicaria	mortality	LC50	48	hours	2042	μg/L			12 ECHA Information on Registered Substances	Lind, D., K. Alto, and S. Chatterton.	Regional Copper-Nickel Study: Aquatic Toxicology Study.	Minnesota Environmental Quality Board		2021/03/02
甲殻類	Daphnia pulicaria	mortality	LC50	48	hours	2717	μg/L			12 ECHA Information on Registered Substances	Lind, D., K. Alto, and S. Chatterton.	Regional Copper-Nickel Study: Aquatic Toxicology Study.	Minnesota Environmental Quality Board		2021/03/02
甲殻類	Daphnia magna		EC50	48	hours	100	mg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia pulicaria	mortality	LC50	48	hours	3607	μg/L			12 ECHA Information on Registered Substances	Lind, D., K. Alto, and S. Chatterton.	Regional Copper-Nickel Study: Aquatic Toxicology Study.	Minnesota Environmental Quality Board		2021/03/02
甲殻類	Daphnia magna	reproduction	EC50	21	days	118	μg/L			12 ECHA Information on Registered Substances	Nys C, Asselman J, Hochmuth JD, Janssen CR, Blust R, Smolders E, and De Schamphelaere KAC	Mixture toxicity of nickel and zinc to Daphnia magna is noninteractive at low effect sizes but becomes synergistic at high effect sizes	Environmental Toxicology and Chemistry; 34(5)		2021/03/02
甲殻類	Ceriodaphnia dubia	Survival	EC10	8	days	2	μg/L			12 ECHA Information on Registered Substances	Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R	Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters	Environmental Toxicology and Chemistry. 37 (10)		2021/03/02
甲殻類	Daphnia magna	mortality	LC10	21	days	250	μg/L			12 ECHA Information on Registered Substances	Pavlaki MD, Pereira R, Loureiro S, Soares AMVM	Effects of binary mixtures on the life traits of Daphnia magna	Ecotoxicology and Environmental Safety. 74		2021/03/02
甲殻類	Daphnia magna	reproduction	EC50	21	days	1035	nmol/L			12 ECHA Information on Registered Substances	Nys C, Asselman J, Hochmuth JD, Janssen CR, Blust R, Smolders E, and De Schamphelaere KAC	Mixture toxicity of nickel and zinc to Daphnia magna is noninteractive at low effect sizes but becomes synergistic at high effect sizes	Environmental Toxicology and Chemistry; 34(5)		2021/03/02
甲殻類	Daphnia magna	mortality	LC20	21	days	300	μg/L			12 ECHA Information on Registered Substances	Pavlaki MD, Pereira R, Loureiro S, Soares AMVM	Effects of binary mixtures on the life traits of Daphnia magna	Ecotoxicology and Environmental Safety. 74		2021/03/02
甲殻類	Daphnia magna	reproduction	EC50	21	days	95	μg/L			12 ECHA Information on Registered Substances	Biesinger, K.E. and G.M. Christensen	Effects of various metals on survival, growth, reproduction, and metabolism of Daphnia magna	Journal of Fisheries Research Board of Canada. 29(12)		2021/03/02
甲殻類	Daphnia magna	mortality	LC50	21	days	130	μg/L			12 ECHA Information on Registered Substances	Biesinger, K.E. and G.M. Christensen	Effects of various metals on survival, growth, reproduction, and metabolism of Daphnia magna	Journal of Fisheries Research Board of Canada. 29(12)		2021/03/02
甲殻類	Daphnia magna	Reproduction and growth of Fo generation	LOEC	21	days	85	μg/L			12 ECHA Information on Registered Substances	Pane, E.F., McGeer, J.C., and C.M. Wood.	Effects of Chronic Waterborne Nickel Exposure on Two Successive Generations of Daphnia magna.	Environ. Toxicol. Chem. 23		2021/03/02
甲殻類	Ceriodaphnia dubia	survival	LOEC	7	days	15	μg/L			12 ECHA Information on Registered Substances	Kszos, L.A., A.J. Stewart, and P.A. Taylor	An evaluation of nickel toxicity to Ceriodaphnia dubia and Daphnia magna in a contaminated stream and in laboratory tests	Environmental Toxicology and Chemistry. 11		2021/03/02
甲殻類	Ceriodaphnia dubia	survival	LOEC	7	days	7.5	μg/L			12 ECHA Information on Registered Substances	Kszos, L.A., A.J. Stewart, and P.A. Taylor	An evaluation of nickel toxicity to Ceriodaphnia dubia and Daphnia magna in a contaminated stream and in laboratory tests	Environmental Toxicology and Chemistry. 11		2021/03/02
甲殻類	Ceriodaphnia dubia	survival and reproduction	NOEC	7	days	7.5	μg/L			12 ECHA Information on Registered Substances	Kszos, L.A., A.J. Stewart, and P.A. Taylor	An evaluation of nickel toxicity to Ceriodaphnia dubia and Daphnia magna in a contaminated stream and in laboratory tests	Environmental Toxicology and Chemistry. 11		2021/03/02
甲殻類	Daphnia magna	reproduction	EC16	21	days	30	μg/L			12 ECHA Information on Registered Substances	Biesinger, K.E. and G.M. Christensen	Effects of various metals on survival, growth, reproduction, and metabolism of Daphnia magna	Journal of Fisheries Research Board of Canada. 29(12)		2021/03/02
甲殻類	Daphnia magna	reproduction	EC10	21	days	800	nmol/L			12 ECHA Information on Registered Substances	Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.	The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.	Environ Toxicol Chem. 2016 May;35(5)		2021/03/02
甲殻類	Daphnia magna	mortality	LC50	21	days	71.9	μg/L			12 ECHA Information on Registered Substances	Pane, E.F., McGeer, J.C., and C.M. Wood.	Effects of Chronic Waterborne Nickel Exposure on Two Successive Generations of Daphnia magna.	Environ. Toxicol. Chem. 23		2021/03/02
甲殻類	Daphnia magna	reproduction	EC50	21	days	412	nmol/L			12 ECHA Information on Registered Substances	Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.	The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.	Environ Toxicol Chem. 2016 May;35(5)		2021/03/02
甲殻類	Daphnia magna	reproduction	EC50	21	days	584	nmol/L			12 ECHA Information on Registered Substances	Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.	The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.	Environ Toxicol Chem. 2016 May;35(5)		2021/03/02
甲殻類	Daphnia magna	reproduction	EC20	21	days	1398	nmol/L			12 ECHA Information on Registered Substances	Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.	The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.	Environ Toxicol Chem. 2016 May;35(5)		2021/03/02
甲殻類	Daphnia magna	reproduction	EC20	21	days	469	nmol/L			12 ECHA Information on Registered Substances	Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.	The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.	Environ Toxicol Chem. 2016 May;35(5)		2021/03/02
甲殻類	Daphnia magna	reproduction	EC50	21	days	3606	nmol/L			12 ECHA Information on Registered Substances	Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.	The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.	Environ Toxicol Chem. 2016 May;35(5)		2021/03/02
甲殻類	Daphnia magna	Reproduction and growth of Fo generation	NOEC	21	days	42	μg/L			12 ECHA Information on Registered Substances	Pane, E.F., McGeer, J.C., and C.M. Wood.	Effects of Chronic Waterborne Nickel Exposure on Two Successive Generations of Daphnia magna.	Environ. Toxicol. Chem. 23		2021/03/02
甲殻類	Daphnia magna	reproduction	EC50	21	days	492	μg/L			12 ECHA Information on Registered Substances	Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.	The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.	Environ Toxicol Chem. 2016 May;35(5)		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	LOEC	10	days	34.9	μgNi/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	NOEC	10	days	21.5	μgNi/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	LOEC	10	days	33.4	μgNi/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	EC20	7	days	4.7	μg/L			12 ECHA Information on Registered Substances	Keithly, J., J.A. Brooker, D.K. DeForest, B.K. Wu, and K.V. Brix	Acute and chronic toxicity of nickel to a cladoceran (Ceriodaphnia dubia) and an amphipod (Hyallela azteca)	Environmental Toxicology and Chemistry, Vol. 23, No.3		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	EC20	7	days	4	μg/L			12 ECHA Information on Registered Substances	Keithly, J., J.A. Brooker, D.K. DeForest, B.K. Wu, and K.V. Brix	Acute and chronic toxicity of nickel to a cladoceran (Ceriodaphnia dubia) and an amphipod (Hyallela azteca)	Environmental Toxicology and Chemistry, Vol. 23, No.3		2021/03/02
甲殻類	Daphnia magna	for 105 mg/L hardness test	ChV	21	days	129	μg/L			12 ECHA Information on Registered Substances		government document			2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	EC20	7	days	6.9	μg/L			12 ECHA Information on Registered Substances	Keithly, J., J.A. Brooker, D.K. DeForest, B.K. Wu, and K.V. Brix	Acute and chronic toxicity of nickel to a cladoceran (Ceriodaphnia dubia) and an amphipod (Hyallela azteca)	Environmental Toxicology and Chemistry, Vol. 23, No.3		2021/03/02
甲殻類	Daphnia magna	reproduction	LOEC	8	weeks	160	μg/L			12 ECHA Information on Registered Substances	Munzinger, A	The influence of Nickel on population dynamics and on some demographic parameters of Daphnia magna	Hydrobiologia. 277		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	EC10	7	days	>2.8～<53.6	μg/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna	reproduction	EC20	21	days	107	μg/L			12 ECHA Information on Registered Substances	Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.	The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.	Environ Toxicol Chem. 2016 May;35(5)		2021/03/02
甲殻類	Daphnia magna	reproduction	EC20	21	days	191	μg/L			12 ECHA Information on Registered Substances	Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.	The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.	Environ Toxicol Chem. 2016 May;35(5)		2021/03/02
甲殻類	Daphnia magna	body length of primiparous individuals (in	LOEC	42	days	80	μg/L			12 ECHA Information on Registered Substances	Munzinger, A	Effects of nickel on Daphnia magna during chronic exposure and alterations in the toxicity to generations pre-exposed to nickel	Wat. Res. 24(7)		2021/03/02
甲殻類	Daphnia magna	body length of primiparous individuals (in	NOEC	42	days	40	μg/L			12 ECHA Information on Registered Substances	Munzinger, A	Effects of nickel on Daphnia magna during chronic exposure and alterations in the toxicity to generations pre-exposed to nickel	Wat. Res. 24(7)		2021/03/02
甲殻類	Daphnia magna	reproduction	LOEC	42	days	80	μg/L			12 ECHA Information on Registered Substances	Munzinger, A	Effects of nickel on Daphnia magna during chronic exposure and alterations in the toxicity to generations pre-exposed to nickel	Wat. Res. 24(7)		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	EC20	7	days	33	μg/L			12 ECHA Information on Registered Substances	Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC	Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata	Environmental Toxicology and Chemistry. 36 (4)		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	EC10	7	days	28	μg/L			12 ECHA Information on Registered Substances	Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC	Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata	Environmental Toxicology and Chemistry. 36 (4)		2021/03/02
甲殻類	Daphnia magna	51 mg/L hardness test	EC50	21	days	14.8	μg/L			12 ECHA Information on Registered Substances		government document			2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	NOEC	10	days	38.6	μgNi/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna	reproduction	LOEC	21	days	>=6.13～<=93.8	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna	reproduction	EC10	21	days	>=8.78～<=76.7	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna	reproduction	EC20	21	days	>=12.7～<=84.3	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC20	7	days	4.8	μg/L			12 ECHA Information on Registered Substances	Keithly, J., J.A. Brooker, D.K. DeForest, B.K. Wu, and K.V. Brix	Acute and chronic toxicity of nickel to a cladoceran (Ceriodaphnia dubia) and an amphipod (Hyallela azteca)	Environmental Toxicology and Chemistry, Vol. 23, No.3		2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC20	7	days	11.9	μg/L			12 ECHA Information on Registered Substances	Keithly, J., J.A. Brooker, D.K. DeForest, B.K. Wu, and K.V. Brix	Acute and chronic toxicity of nickel to a cladoceran (Ceriodaphnia dubia) and an amphipod (Hyallela azteca)	Environmental Toxicology and Chemistry, Vol. 23, No.3		2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC20	7	days	10.4	μg/L			12 ECHA Information on Registered Substances	Keithly, J., J.A. Brooker, D.K. DeForest, B.K. Wu, and K.V. Brix	Acute and chronic toxicity of nickel to a cladoceran (Ceriodaphnia dubia) and an amphipod (Hyallela azteca)	Environmental Toxicology and Chemistry, Vol. 23, No.3		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	NOEC	7	days	5.3～15.3	μg/L			12 ECHA Information on Registered Substances	Keithly, J., J.A. Brooker, D.K. DeForest, B.K. Wu, and K.V. Brix	Acute and chronic toxicity of nickel to a cladoceran (Ceriodaphnia dubia) and an amphipod (Hyallela azteca)	Environmental Toxicology and Chemistry, Vol. 23, No.3		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	EC20	7	days	<3.8	μg/L			12 ECHA Information on Registered Substances	Keithly, J., J.A. Brooker, D.K. DeForest, B.K. Wu, and K.V. Brix	Acute and chronic toxicity of nickel to a cladoceran (Ceriodaphnia dubia) and an amphipod (Hyallela azteca)	Environmental Toxicology and Chemistry, Vol. 23, No.3		2021/03/02
甲殻類	Daphnia magna	growth	NOEC	11	days	21	μg/L			12 ECHA Information on Registered Substances	Pane, E.F., McGeer, J.C., and C.M. Wood.	Effects of Chronic Waterborne Nickel Exposure on Two Successive Generations of Daphnia magna.	Environ. Toxicol. Chem. 23		2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	LC20	7	days	<3.8	μg/L			12 ECHA Information on Registered Substances	Keithly, J., J.A. Brooker, D.K. DeForest, B.K. Wu, and K.V. Brix	Acute and chronic toxicity of nickel to a cladoceran (Ceriodaphnia dubia) and an amphipod (Hyallela azteca)	Environmental Toxicology and Chemistry, Vol. 23, No.3		2021/03/02
甲殻類	Daphnia magna	reproduction	EC50	21	days	134	μg/L			12 ECHA Information on Registered Substances	Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.	The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.	Environ Toxicol Chem. 2016 May;35(5)		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	LOEC	10	days	62.4	μgNi/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	NOEC	10	days	20.2	μgNi/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna	mortality	LOEC	21	days	>37.4～<=257	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna	mortality	LC50	21	days	>37.4～<=144	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna	reproduction	EC50	21	days	>=23.6～<=108	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna	reproduction	NOEC	21	days	6.13～<=48.5	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna	reproduction	% reduction in reproduction	21	days	0.4	mg/L			12 ECHA Information on Registered Substances	Bozich J, Hang M, Hamers R, Klaper R	Core chemistry influences the toxicity of multicomponent metal oxide nanomaterials, lithium nickel manganese cobalt oxide, and lithium cobalt oxide to Daphnia magna	Environ Toxicol Chem; 36(9)		2021/03/02
甲殻類	Daphnia magna	survival and reproduction	NOEC	21	days	90	μg/L			12 ECHA Information on Registered Substances	Kuhn, R., M. Pattard, K-D. Pernak, and A. Winter	Results of the harmful effects of water pollutants to Daphnia magna in the 21 day reproduction test	Water Res. 23(4)		2021/03/02
甲殻類	Daphnia magna	mortality	NOEC	21	days	>=37～<=150	μg/L	○		12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Ceriodaphnia dubia	Mortality	NR-LETH	7	days	7.5	μg/L			16 ECOTOX	Kszos,L.A., A.J. Stewart, and P.A. Taylor	An Evaluation of Nickel Toxicity to Ceriodaphnia dubia and Daphnia magna in a Contaminated Stream and in Laboratory Tests	Environ. Toxicol. Chem.11(7)		2020/11/12
甲殻類	Daphnia magna	reproduction	EC10	21	days	94	μg/L			12 ECHA Information on Registered Substances	Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.	The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.	Environ Toxicol Chem. 2016 May;35(5)		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	NOEC	10	days	<8.3	μgNi/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Chironomus riparius	Growth	MATC	30	days	1100	μg/L			16 ECOTOX	Powlesland,C., and J. George	Acute and Chronic Toxicity of Nickel to Larvae of Chironomus riparis (Meigen)	Environ. Pollut. A.42(1)		2020/11/12
甲殻類	Daphnia magna	mortality	% mortality	21	days	0.4	mg/L			12 ECHA Information on Registered Substances	Bozich J, Hang M, Hamers R, Klaper R	Core chemistry influences the toxicity of multicomponent metal oxide nanomaterials, lithium nickel manganese cobalt oxide, and lithium cobalt oxide to Daphnia magna	Environ Toxicol Chem; 36(9)		2021/03/02
甲殻類	Daphnia magna	reproduction	NOEC	42	days	40	μg/L			12 ECHA Information on Registered Substances	Munzinger, A	Effects of nickel on Daphnia magna during chronic exposure and alterations in the toxicity to generations pre-exposed to nickel	Wat. Res. 24(7)		2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	EC50	7	days	ca.43～ca.52	μg/L			12 ECHA Information on Registered Substances	Nys C, Janssen CR, Blust R, Smolders E, de Schamphelaere KAC	Reproductive toxicity of binary and ternary mixture combinations of nickel, zinc, and lead to Ceriodaphnia dubia is best predicted with the independent action model	Environmental Toxicology & Chemistry; 35(7)		2021/03/02
甲殻類	Ceriodaphnia dubia	mortality	EC50	7	days	ca.478～ca.546	nmol/L			12 ECHA Information on Registered Substances	Nys C, Janssen CR, Blust R, Smolders E, de Schamphelaere KAC	Reproductive toxicity of binary and ternary mixture combinations of nickel, zinc, and lead to Ceriodaphnia dubia is best predicted with the independent action model	Environmental Toxicology & Chemistry; 35(7)		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	NOEC	10	days	<3.7	μgNi/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna	reproduction	EC50	21	days	1652	nmol/L			12 ECHA Information on Registered Substances	Nys C, Asselman J, Hochmuth JD, Janssen CR, Blust R, Smolders E, and De Schamphelaere KAC	Mixture toxicity of nickel and zinc to Daphnia magna is noninteractive at low effect sizes but becomes synergistic at high effect sizes	Environmental Toxicology and Chemistry; 34(5)		2021/03/02
甲殻類	Daphnia magna	reproduction	EC10	21	days	109	μg/L			12 ECHA Information on Registered Substances	Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.	The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.	Environ Toxicol Chem. 2016 May;35(5)		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	NOEC	10	days	<12.2	μgNi/L			12 ECHA Information on Registered Substances		study report			2021/03/02
甲殻類	Daphnia magna	growth	NOEC	8	weeks	40	μg/L			12 ECHA Information on Registered Substances	Munzinger, A	The influence of Nickel on population dynamics and on some demographic parameters of Daphnia magna	Hydrobiologia. 277		2021/03/02
甲殻類	Daphnia magna	mortality, growth and reproduction	LOEC	21	days	0.32	mg/L			12 ECHA Information on Registered Substances	Enserink, E.L., J.L. Maas-Diepeveen, and C.J. Van Leeuwen	Combined effects of metals; an ecotoxicological evaluation	Wat. Res. 25(6)		2021/03/02
甲殻類	Daphnia magna	reproduction	EC50	21	days	289.29	μg/L			12 ECHA Information on Registered Substances	Pavlaki MD, Pereira R, Loureiro S, Soares AMVM	Effects of binary mixtures on the life traits of Daphnia magna	Ecotoxicology and Environmental Safety. 74		2021/03/02
甲殻類	Daphnia magna	mortality	LC100	15	days	350	μg/L			12 ECHA Information on Registered Substances	Pavlaki MD, Pereira R, Loureiro S, Soares AMVM	Effects of binary mixtures on the life traits of Daphnia magna	Ecotoxicology and Environmental Safety. 74		2021/03/02
甲殻類	Daphnia magna	mortality, growth and reproduction	NOEC	21	days	0.2	mg/L			12 ECHA Information on Registered Substances	Enserink, E.L., J.L. Maas-Diepeveen, and C.J. Van Leeuwen	Combined effects of metals; an ecotoxicological evaluation	Wat. Res. 25(6)		2021/03/02
甲殻類	Daphnia magna	mortality, growth and reproduction	LC50	21	days	0.36	mg/L			12 ECHA Information on Registered Substances	Enserink, E.L., J.L. Maas-Diepeveen, and C.J. Van Leeuwen	Combined effects of metals; an ecotoxicological evaluation	Wat. Res. 25(6)		2021/03/02
甲殻類	Daphnia magna	for 205 mg/L hardness test	ChV	21	days	357	μg/L			12 ECHA Information on Registered Substances		government document			2021/03/02
甲殻類	Daphnia magna	growth	LOEC	8	weeks	80	μg/L			12 ECHA Information on Registered Substances	Munzinger, A	The influence of Nickel on population dynamics and on some demographic parameters of Daphnia magna	Hydrobiologia. 277		2021/03/02
甲殻類	Daphnia magna	growth	LOEC	11	days	42	μg/L			12 ECHA Information on Registered Substances	Pane, E.F., McGeer, J.C., and C.M. Wood.	Effects of Chronic Waterborne Nickel Exposure on Two Successive Generations of Daphnia magna.	Environ. Toxicol. Chem. 23		2021/03/02
甲殻類	Daphnia magna	reproduction	NOEC	21	days	140	μg/L			12 ECHA Information on Registered Substances	Perez E, Hoang TC	Responses of Daphnia magna to chronic exposure of cadium and nickel mixtures	Chemosphere. 208		2021/03/02
甲殻類	Daphnia magna	reproduction	NOEC	21	days	>=160	μg/L			12 ECHA Information on Registered Substances	Perez E, Hoang TC	Responses of Daphnia magna to chronic exposure of cadium and nickel mixtures	Chemosphere. 208		2021/03/02
甲殻類	Daphnia magna	reproduction	NOEC	8	weeks	120	μg/L			12 ECHA Information on Registered Substances	Munzinger, A	The influence of Nickel on population dynamics and on some demographic parameters of Daphnia magna	Hydrobiologia. 277		2021/03/02
甲殻類	Daphnia magna	reproduction	EC50			17.3	μg/L			12 ECHA Information on Registered Substances	Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC	Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation	Environmental Toxicology and Chemistry 37		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	EC10	7	days	81	nmol/L			12 ECHA Information on Registered Substances	Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC	Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata	Environmental Toxicology and Chemistry. 36 (4)		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	EC20	7	days	120	nmol/L			12 ECHA Information on Registered Substances	Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC	Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata	Environmental Toxicology and Chemistry. 36 (4)		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	EC50	7	days	240	nmol/L			12 ECHA Information on Registered Substances	Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC	Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata	Environmental Toxicology and Chemistry. 36 (4)		2021/03/02
甲殻類	Daphnia magna	reproduction	EC50			82.1	μg/L			12 ECHA Information on Registered Substances	Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC	Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation	Environmental Toxicology and Chemistry 37		2021/03/02
甲殻類	Daphnia magna	reproduction	EC20			40	μg/L			12 ECHA Information on Registered Substances	Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC	Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation	Environmental Toxicology and Chemistry 37		2021/03/02
甲殻類	Daphnia magna	reproduction	EC50			12.9	μg/L			12 ECHA Information on Registered Substances	Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC	Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation	Environmental Toxicology and Chemistry 37		2021/03/02
甲殻類	Ceriodaphnia dubia	Survival	EC50	8	days	20.1	μg/L			12 ECHA Information on Registered Substances	Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R	Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters	Environmental Toxicology and Chemistry. 37 (10)		2021/03/02
甲殻類	Daphnia magna	reproduction	EC50			129.1	μg/L			12 ECHA Information on Registered Substances	Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC	Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation	Environmental Toxicology and Chemistry 37		2021/03/02
甲殻類	Ceriodaphnia dubia	Survival	EC10	8	days	6.2	μg/L			12 ECHA Information on Registered Substances	Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R	Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters	Environmental Toxicology and Chemistry. 37 (10)		2021/03/02
甲殻類	Daphnia magna	reproduction	EC20			105.2	μg/L			12 ECHA Information on Registered Substances	Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC	Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation	Environmental Toxicology and Chemistry 37		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	EC50	7	days	400	nmol/L			12 ECHA Information on Registered Substances	Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC	Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata	Environmental Toxicology and Chemistry. 36 (4)		2021/03/02
甲殻類	Daphnia magna	reproduction	EC50			75.1	μg/L			12 ECHA Information on Registered Substances	Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC	Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation	Environmental Toxicology and Chemistry 37		2021/03/02
甲殻類	Daphnia magna	reproduction	EC10			24.4	μg/L			12 ECHA Information on Registered Substances	Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC	Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation	Environmental Toxicology and Chemistry 37		2021/03/02
甲殻類	Ceriodaphnia dubia	Survival	EC50	7	days	11.8	μg/L			12 ECHA Information on Registered Substances	Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R	Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters	Environmental Toxicology and Chemistry. 37 (10)		2021/03/02
甲殻類	Daphnia magna	reproduction	NOEC	21	days	40	μg/L			12 ECHA Information on Registered Substances	Perez E, Hoang TC	Responses of Daphnia magna to chronic exposure of cadium and nickel mixtures	Chemosphere. 208		2021/03/02
甲殻類	Daphnia magna	growth	NOEC	21	days	40	μg/L			12 ECHA Information on Registered Substances	Perez E, Hoang TC	Responses of Daphnia magna to chronic exposure of cadium and nickel mixtures	Chemosphere. 208		2021/03/02
甲殻類	Daphnia magna	mortality	NOEC	21	days	40	μg/L			12 ECHA Information on Registered Substances	Perez E, Hoang TC	Responses of Daphnia magna to chronic exposure of cadium and nickel mixtures	Chemosphere. 208		2021/03/02
甲殻類	Daphnia magna	reproduction	EC20			113.1	μg/L			12 ECHA Information on Registered Substances	Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC	Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation	Environmental Toxicology and Chemistry 37		2021/03/02
甲殻類	Daphnia magna	reproduction	EC50			143.2	μg/L			12 ECHA Information on Registered Substances	Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC	Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation	Environmental Toxicology and Chemistry 37		2021/03/02
甲殻類	Ceriodaphnia dubia	Survival	EC50	8	days	6.7	μg/L			12 ECHA Information on Registered Substances	Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R	Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters	Environmental Toxicology and Chemistry. 37 (10)		2021/03/02
甲殻類	Ceriodaphnia dubia	Survival	EC50	8	days	4.4	μg/L			12 ECHA Information on Registered Substances	Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R	Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters	Environmental Toxicology and Chemistry. 37 (10)		2021/03/02
甲殻類	Ceriodaphnia dubia	survival and reproduction	NOEC	7	days	3.8	μg/L			12 ECHA Information on Registered Substances	Kszos, L.A., A.J. Stewart, and P.A. Taylor	An evaluation of nickel toxicity to Ceriodaphnia dubia and Daphnia magna in a contaminated stream and in laboratory tests	Environmental Toxicology and Chemistry. 11		2021/03/02
甲殻類	Daphnia magna	reproduction	EC50	21	days	165	μg/L			12 ECHA Information on Registered Substances	Nys C, Asselman J, Hochmuth JD, Janssen CR, Blust R, Smolders E, and De Schamphelaere KAC	Mixture toxicity of nickel and zinc to Daphnia magna is noninteractive at low effect sizes but becomes synergistic at high effect sizes	Environmental Toxicology and Chemistry; 34(5)		2021/03/02
甲殻類	Daphnia magna	reproduction	EC10			93.3	μg/L			12 ECHA Information on Registered Substances	Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC	Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation	Environmental Toxicology and Chemistry 37		2021/03/02
甲殻類	Daphnia magna	reproduction	EC10			98.5	μg/L			12 ECHA Information on Registered Substances	Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC	Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation	Environmental Toxicology and Chemistry 37		2021/03/02
甲殻類	Daphnia magna	reproduction	EC10			18.8	μg/L			12 ECHA Information on Registered Substances	Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC	Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation	Environmental Toxicology and Chemistry 37		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	EC20	7	days	303	nmol/L			12 ECHA Information on Registered Substances	Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC	Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata	Environmental Toxicology and Chemistry. 36 (4)		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	EC10	7	days	258	nmol/L			12 ECHA Information on Registered Substances	Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC	Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata	Environmental Toxicology and Chemistry. 36 (4)		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	EC50	7	days	27	μg/L			12 ECHA Information on Registered Substances	Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC	Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata	Environmental Toxicology and Chemistry. 36 (4)		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	EC20	7	days	14	μg/L			12 ECHA Information on Registered Substances	Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC	Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata	Environmental Toxicology and Chemistry. 36 (4)		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	EC10	7	days	10	μg/L			12 ECHA Information on Registered Substances	Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC	Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata	Environmental Toxicology and Chemistry. 36 (4)		2021/03/02
甲殻類	Ceriodaphnia dubia	Survival	EC10	7	days	4.9	μg/L			12 ECHA Information on Registered Substances	Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R	Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters	Environmental Toxicology and Chemistry. 37 (10)		2021/03/02
甲殻類	Daphnia magna	reproduction	LOEC	21	days	80	μg/L			12 ECHA Information on Registered Substances	Perez E, Hoang TC	Responses of Daphnia magna to chronic exposure of cadium and nickel mixtures	Chemosphere. 208		2021/03/02
甲殻類	Ceriodaphnia dubia	reproduction	EC50	7	days	43	μg/L			12 ECHA Information on Registered Substances	Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC	Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata	Environmental Toxicology and Chemistry. 36 (4)		2021/03/02
甲殻類	Daphnia magna	mortality	LOEC	21	days	80	μg/L			12 ECHA Information on Registered Substances	Perez E, Hoang TC	Responses of Daphnia magna to chronic exposure of cadium and nickel mixtures	Chemosphere. 208		2021/03/02
甲殻類	Ceriodaphnia dubia	Survival	EC10	8	days	3.6	μg/L			12 ECHA Information on Registered Substances	Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R	Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters	Environmental Toxicology and Chemistry. 37 (10)		2021/03/02
甲殻類	Daphnia magna	growth	LOEC	21	days	80	μg/L			12 ECHA Information on Registered Substances	Perez E, Hoang TC	Responses of Daphnia magna to chronic exposure of cadium and nickel mixtures	Chemosphere. 208		2021/03/02
甲殻類	Daphnia magna	reproduction	EC20			32.6	μg/L			12 ECHA Information on Registered Substances	Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC	Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation	Environmental Toxicology and Chemistry 37		2021/03/02
魚類	Gasterosteus aculeatus (Three-spined stickleback)	Mortality	NR-LETH	10	days	800	μg/L			16 ECOTOX	Jones,J.R.E.	The Relation Between the Electrolytic Solution Pressures of the Metals and Their Toxicity to the Stickleback (Gasterosteus aculeatus L.)	J. Exp. Biol.16(4)		2020/11/12
魚類	Oncorhynchus mykiss (Rainbow trout)	Mortality	LC50	4	days	35500	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Hale,J.G.	Toxicity of Metal Mining Wastes	Bull. Environ. Contam. Toxicol.17(1): 66-73	1977	2016/03/25
魚類	Pimephales promelas (Fathead minnow)	Mortality	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2016/03/25
魚類	Pimephales promelas (Fathead minnow)	Reproduction	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2016/03/25
魚類	Pimephales promelas (Fathead minnow)	Reproduction	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2016/03/25
魚類	Pimephales promelas (Fathead minnow)	Biochemical	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2016/03/25
魚類	Pimephales promelas (Fathead minnow)	Growth	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2016/03/25
魚類	Gasterosteus aculeatus (Three-spined stickleback)	Mortality		10	days	800	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Jones,J.R.E.	The Relation Between the Electrolytic Solution Pressures of the Metals and Their Toxicity to the Stickleback (Gasterosteus aculeatus L.)	J. Exp. Biol.16(4): 425-437	1939	2016/03/25
魚類	Cyprinus carpio (Carp)	Mortality	LC50	2	days	29100	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Rehwoldt,R., G. Bida, and B. Nerrie	Acute Toxicity of Copper, Nickel, and Zinc Ions to Some Hudson River Fish Species	Bull. Environ. Contam. Toxicol.6(5): 445-448	1971	2016/03/25
魚類	Cyprinus carpio (Carp)	Mortality	LC50	4	days	10600	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Rehwoldt,R., G. Bida, and B. Nerrie	Acute Toxicity of Copper, Nickel, and Zinc Ions to Some Hudson River Fish Species	Bull. Environ. Contam. Toxicol.6(5): 445-448	1971	2016/03/25
魚類	Cyprinus carpio (Carp)	Mortality	LC50	1	days	38200	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Rehwoldt,R., G. Bida, and B. Nerrie	Acute Toxicity of Copper, Nickel, and Zinc Ions to Some Hudson River Fish Species	Bull. Environ. Contam. Toxicol.6(5): 445-448	1971	2016/03/25
魚類	Pimephales promelas (Fathead minnow)	Reproduction	LOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2016/03/25
魚類	Pimephales promelas (Fathead minnow)	Growth	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2016/03/25
魚類	Pimephales promelas (Fathead minnow)	Biochemical	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2016/03/25
魚類	Pimephales promelas (Fathead minnow)	Accumulation	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2016/03/25
魚類	Pimephales promelas (Fathead minnow)	Biochemical	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2016/03/25
魚類	Pimephales promelas (Fathead minnow)	Accumulation	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2016/03/25
魚類	Pimephales promelas (Fathead minnow)	Growth	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2016/03/25
魚類	Pimephales promelas (Fathead minnow)	Biochemical	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2016/03/25
魚類	Pimephales promelas (Fathead minnow)	Growth	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2016/03/25
魚類	Pimephales promelas (Fathead minnow)	Growth	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2016/03/25
魚類	Pimephales promelas (Fathead minnow)	Growth	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2016/03/25
魚類	Pimephales promelas (Fathead minnow)	Accumulation	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2016/03/25
魚類	Pimephales promelas (Fathead minnow)	Accumulation	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2016/03/25
魚類	Pimephales promelas (Fathead minnow)	Growth	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2016/03/25
魚類	Pimephales promelas (Fathead minnow)	Growth	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2017/03/15
魚類	Pimephales promelas (Fathead minnow)	Growth	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2017/03/15
魚類	Pimephales promelas (Fathead minnow)	Accumulation	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2017/03/15
魚類	Pimephales promelas (Fathead minnow)	Accumulation	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2017/03/15
魚類	Pimephales promelas (Fathead minnow)	Accumulation	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2017/03/15
魚類	Pimephales promelas (Fathead minnow)	Growth	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2017/03/15
魚類	Pimephales promelas (Fathead minnow)	Reproduction	LOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2017/03/15
魚類	Oncorhynchus mykiss (Rainbow trout)	Mortality	LC50	4	days	35500	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Hale,J.G.	Toxicity of Metal Mining Wastes	Bull. Environ. Contam. Toxicol.17(1): 66-73	1977	2017/03/15
魚類	Pimephales promelas (Fathead minnow)	Growth	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2017/03/15
魚類	Gasterosteus aculeatus (Three-spined stickleback)	Mortality		10	days	800	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Jones,J.R.E.	The Relation Between the Electrolytic Solution Pressures of the Metals and Their Toxicity to the Stickleback (Gasterosteus aculeatus L.)	J. Exp. Biol.16(4): 425-437	1939	2017/03/15
魚類	Pimephales promelas (Fathead minnow)	Growth	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2017/03/15
魚類	Pimephales promelas (Fathead minnow)	Growth	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2017/03/15
魚類	Pimephales promelas (Fathead minnow)	Biochemical	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2017/03/15
魚類	Pimephales promelas (Fathead minnow)	Reproduction	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2017/03/15
魚類	Pimephales promelas (Fathead minnow)	Mortality	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2017/03/15
魚類	Pimephales promelas (Fathead minnow)	Biochemical	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2017/03/15
魚類	Cyprinus carpio (Carp)	Mortality	LC50	1	days	38200	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Rehwoldt,R., G. Bida, and B. Nerrie	Acute Toxicity of Copper, Nickel, and Zinc Ions to Some Hudson River Fish Species	Bull. Environ. Contam. Toxicol.6(5): 445-448	1971	2017/03/15
魚類	Cyprinus carpio (Carp)	Mortality	LC50	2	days	29100	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Rehwoldt,R., G. Bida, and B. Nerrie	Acute Toxicity of Copper, Nickel, and Zinc Ions to Some Hudson River Fish Species	Bull. Environ. Contam. Toxicol.6(5): 445-448	1971	2017/03/15
魚類	Cyprinus carpio (Carp)	Mortality	LC50	4	days	10600	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Rehwoldt,R., G. Bida, and B. Nerrie	Acute Toxicity of Copper, Nickel, and Zinc Ions to Some Hudson River Fish Species	Bull. Environ. Contam. Toxicol.6(5): 445-448	1971	2017/03/15
魚類	Pimephales promelas (Fathead minnow)	Reproduction	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2017/03/15
魚類	Pimephales promelas (Fathead minnow)	Growth	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2017/03/15
魚類	Pimephales promelas (Fathead minnow)	Biochemical	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2017/03/15
魚類	Pimephales promelas (Fathead minnow)	Accumulation	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2017/03/15
魚類	Pimephales promelas (Fathead minnow)	Biochemical	NOEC	21	days	91.33	μg/L			16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)	Ouellette,J.D., M.G. Dube, and S. Niyogi	A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)	Water Air Soil Pollut.224(1462): 44 p.	2013	2017/03/15
魚類	Poecilia reticulata (Guppy)	mortality	LC50	48	hours	29.66	mg/L			12 ECHA Information on Registered Substances	Shuhaimi-Othman M, Yakub N, Ramle N-A, and Abas A.	Comparative toxicity of eight metals on freshwater fish.	Toxicology and Industrial Health; DOI		2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	5.18	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H. and C. Henderson	The acute toxicity of some heavy metals to different species of warmwater fishes	Air Wat. Pollut. Int. J. 10		2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	25	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H.	Chronic toxicity of nickel to the fathead minnow	J. Water Pollut. Control Fed. 46(4)		2021/03/02
魚類	Poecilia reticulata (Guppy)	mortality	LC50	48	hours	204.2	mg/L			12 ECHA Information on Registered Substances	Khunyakari, R.P., V. Tare, and R.N. Sharma.	Effects of some trace heavy metals on Poecilia reticulata (Peters).	Journal of Environmental Biology. 22(2)		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	72	hours	8.46	mgNi/L			12 ECHA Information on Registered Substances	Blaylock, B.G. and M.L. Frank.	A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).	Bull. Environ. Contam. Toxicol. 21(4/5)		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	96	hours	6.16	mgNi/L			12 ECHA Information on Registered Substances	Blaylock, B.G. and M.L. Frank.	A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).	Bull. Environ. Contam. Toxicol. 21(4/5)		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	257	hours	0.75	mgNi/L			12 ECHA Information on Registered Substances	Blaylock, B.G. and M.L. Frank.	A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).	Bull. Environ. Contam. Toxicol. 21(4/5)		2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	2916～17678	μg/L			12 ECHA Information on Registered Substances	Lind, D., K. Alto, and S. Chatterton.	Regional Copper-Nickel Study: Aquatic Toxicology Study.	Minnesota Environmental Quality Board		2021/03/02
魚類	Poecilia reticulata (Guppy)	mortality	LC50	24	hours	336	mg/L			12 ECHA Information on Registered Substances	Khunyakari, R.P., V. Tare, and R.N. Sharma.	Effects of some trace heavy metals on Poecilia reticulata (Peters).	Journal of Environmental Biology. 22(2)		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	TLm	96	hours	10.4～10.6	mg/L			12 ECHA Information on Registered Substances	Rehwoldt, R., G. Bida, and B. Nerrie.	Acute toxicity of copper, nickel and zinc ions to some Hudson River fish species.	Bull. Environ. Contam. Toxicol. 6(5)		2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	4.58	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H. and C. Henderson	The acute toxicity of some heavy metals to different species of warmwater fishes	Air Wat. Pollut. Int. J. 10		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	72	hours	6.1	mgNi/L			12 ECHA Information on Registered Substances	Blaylock, B.G. and M.L. Frank.	A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).	Bull. Environ. Contam. Toxicol. 21(4/5)		2021/03/02
魚類	Pimephales promelas	enzyme activities	NOEC	7	days	>=0.38	μmol nickel/g tissue			12 ECHA Information on Registered Substances		publication			2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	32	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H.	Chronic toxicity of nickel to the fathead minnow	J. Water Pollut. Control Fed. 46(4)		2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	28	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H.	Chronic toxicity of nickel to the fathead minnow	J. Water Pollut. Control Fed. 46(4)		2021/03/02
魚類	Lepomis macrochirus	mortality	LC50	96	hours	21.2	mg/L			12 ECHA Information on Registered Substances	Cairns, J., K.W. Thompson, and A.C. Hendricks	Effects of Fluctuating, Sublethal Applications of Heavy Metal Solutions Upon the Gill Ventilation Response of Bluegills (Lepomis macrochirus)	PB81-150997 or EPA-600/3-81-003		2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	1.12	mg/L			12 ECHA Information on Registered Substances	Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl	The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas)	Water, Air, and Soil Pollution. 133		2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	>4000	μg/L			12 ECHA Information on Registered Substances	Schubauer-Berigan, M.K., J.R. Dierkes, P.D. Monson, and G.T. Ankley	pH-Dependent toxicity of Cd, Cu, Ni, Pb and Zn to Ceriodaphnia dubia, Pimephales Promelas, Hyalella azteca and Lumbriculus variegates	Environmental Toxicology and Chemistry. 12		2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	3400	μg/L			12 ECHA Information on Registered Substances	Schubauer-Berigan, M.K., J.R. Dierkes, P.D. Monson, and G.T. Ankley	pH-Dependent toxicity of Cd, Cu, Ni, Pb and Zn to Ceriodaphnia dubia, Pimephales Promelas, Hyalella azteca and Lumbriculus variegates	Environmental Toxicology and Chemistry. 12		2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	42.4	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H. and C. Henderson	The acute toxicity of some heavy metals to different species of warmwater fishes	Air Wat. Pollut. Int. J. 10		2021/03/02
魚類	Poecilia reticulata (Guppy)	mortality	LC50	96	hours	36	mg/L			12 ECHA Information on Registered Substances	Khangarot, B.S. and P.K. Ray	Acute toxicity and toxic interaction of chromium and nickel to common guppy Poecilla reticulata (Peters).	Bull. Environ. Contam. Toxicol. 44		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	233	hours	1.3	mgNi/L			12 ECHA Information on Registered Substances	Blaylock, B.G. and M.L. Frank.	A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).	Bull. Environ. Contam. Toxicol. 21(4/5)		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	212	hours	2.14	mgNi/L			12 ECHA Information on Registered Substances	Blaylock, B.G. and M.L. Frank.	A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).	Bull. Environ. Contam. Toxicol. 21(4/5)		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	184	hours	3.18	mgNi/L			12 ECHA Information on Registered Substances	Blaylock, B.G. and M.L. Frank.	A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).	Bull. Environ. Contam. Toxicol. 21(4/5)		2021/03/02
魚類	Oncorhynchus mykiss (Rainbow trout)	Mortality	LC50	96	hours	35.5	mg/L			16 ECOTOX	Hale,J.G.	Toxicity of Metal Mining Wastes	Bull. Environ. Contam. Toxicol.17(1)		2020/11/12
魚類	Cyprinus carpio (Carp)	Mortality	LC50	48	hours	29100	μg/L			16 ECOTOX	Rehwoldt,R., G. Bida, and B. Nerrie	Acute Toxicity of Copper, Nickel, and Zinc Ions to Some Hudson River Fish Species	Bull. Environ. Contam. Toxicol.6(5)		2020/11/12
魚類	Cyprinus carpio (Carp)	Mortality	LC50	96	hours	10600	μg/L			16 ECOTOX	Rehwoldt,R., G. Bida, and B. Nerrie	Acute Toxicity of Copper, Nickel, and Zinc Ions to Some Hudson River Fish Species	Bull. Environ. Contam. Toxicol.6(5)		2020/11/12
魚類	Cyprinus carpio (Carp)	Mortality	LC50	24	hours	38200	μg/L			16 ECOTOX	Rehwoldt,R., G. Bida, and B. Nerrie	Acute Toxicity of Copper, Nickel, and Zinc Ions to Some Hudson River Fish Species	Bull. Environ. Contam. Toxicol.6(5)		2020/11/12
魚類	Pimephales promelas		LC50	96	hours	40	mg/L			12 ECHA Information on Registered Substances	Ewell, W.S., J.W. Gorsuch, R.O. Kringle, K.A. Robillard, and R.C. Spiegel	Simultaneous evaluation of the acute effects of chemicals on seven aquatic species	Environmental Toxicology and Chemistry. 5		2021/03/02
魚類	Poecilia reticulata (Guppy)	mortality	LC50	24	hours	95	mg/L			12 ECHA Information on Registered Substances	Khangarot, B.S. and P.K. Ray	Acute toxicity and toxic interaction of chromium and nickel to common guppy Poecilla reticulata (Peters).	Bull. Environ. Contam. Toxicol. 44		2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	0.35	mg/L			12 ECHA Information on Registered Substances	Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl	The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas)	Water, Air, and Soil Pollution. 133		2021/03/02
魚類	Poecilia reticulata (Guppy)	mortality	LC50	72	hours	50.12	mg/L			12 ECHA Information on Registered Substances	Khangarot, B.S. and P.K. Ray	Acute toxicity and toxic interaction of chromium and nickel to common guppy Poecilla reticulata (Peters).	Bull. Environ. Contam. Toxicol. 44		2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	3100	μg/L			12 ECHA Information on Registered Substances	Schubauer-Berigan, M.K., J.R. Dierkes, P.D. Monson, and G.T. Ankley	pH-Dependent toxicity of Cd, Cu, Ni, Pb and Zn to Ceriodaphnia dubia, Pimephales Promelas, Hyalella azteca and Lumbriculus variegates	Environmental Toxicology and Chemistry. 12		2021/03/02
魚類	Poecilia reticulata (Guppy)	mortality	LC50	168	hours	33.11	mg/L			12 ECHA Information on Registered Substances	Khangarot, B.S. and P.K. Ray	Acute toxicity and toxic interaction of chromium and nickel to common guppy Poecilla reticulata (Peters).	Bull. Environ. Contam. Toxicol. 44		2021/03/02
魚類	Poecilia reticulata (Guppy)	mortality	LC50	240	hours	31.15	mg/L			12 ECHA Information on Registered Substances	Khangarot, B.S. and P.K. Ray	Acute toxicity and toxic interaction of chromium and nickel to common guppy Poecilla reticulata (Peters).	Bull. Environ. Contam. Toxicol. 44		2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	0.45	mg/L			12 ECHA Information on Registered Substances	Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl	The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas)	Water, Air, and Soil Pollution. 133		2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	2.27	mg/L			12 ECHA Information on Registered Substances	Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl	The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas)	Water, Air, and Soil Pollution. 133		2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	0.5	mg/L			12 ECHA Information on Registered Substances	Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl	The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas)	Water, Air, and Soil Pollution. 133		2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	0.69	mg/L			12 ECHA Information on Registered Substances	Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl	The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas)	Water, Air, and Soil Pollution. 133		2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	0.54	mg/L			12 ECHA Information on Registered Substances	Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl	The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas)	Water, Air, and Soil Pollution. 133		2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	27	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H.	Chronic toxicity of nickel to the fathead minnow	J. Water Pollut. Control Fed. 46(4)		2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	2.21	mg/L			12 ECHA Information on Registered Substances	Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl	The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas)	Water, Air, and Soil Pollution. 133		2021/03/02
魚類	Poecilia reticulata (Guppy)	mortality	LC50	24	hours	54.43	mg/L			12 ECHA Information on Registered Substances	Shuhaimi-Othman M, Yakub N, Ramle N-A, and Abas A.	Comparative toxicity of eight metals on freshwater fish.	Toxicology and Industrial Health; DOI		2021/03/02
魚類	Poecilia reticulata (Guppy)	mortality	LC50	48	hours	63	mg/L			12 ECHA Information on Registered Substances	Khangarot, B.S. and P.K. Ray	Acute toxicity and toxic interaction of chromium and nickel to common guppy Poecilla reticulata (Peters).	Bull. Environ. Contam. Toxicol. 44		2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	44.5	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H. and C. Henderson	The acute toxicity of some heavy metals to different species of warmwater fishes	Air Wat. Pollut. Int. J. 10		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	96	hours	14.7	mg/L			12 ECHA Information on Registered Substances	Ghosh A, Kaviraj A, Saha S	Deposition, acute toxicity, and bioaccumulation of nickel in some freshwater organisms with best-fit functions modeling	Environ Sci Pollut Res 25		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	48	hours	27.88	mg/L			12 ECHA Information on Registered Substances	Ghosh A, Kaviraj A, Saha S	Deposition, acute toxicity, and bioaccumulation of nickel in some freshwater organisms with best-fit functions modeling	Environ Sci Pollut Res 25		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	72	hours	24.08	mg/L			12 ECHA Information on Registered Substances	Ghosh A, Kaviraj A, Saha S	Deposition, acute toxicity, and bioaccumulation of nickel in some freshwater organisms with best-fit functions modeling	Environ Sci Pollut Res 25		2021/03/02
魚類	Cyprinus carpio (Carp)	Mortality	LC50	96	hours	10.6	mgNi/L [nominal]			8 NITE 化学物質の初期リスク評価書	Rehwoldt, R., Bida, G. and Nerrie, B.	Acute toxicity of copper, nickel, and zinc Ions to some Hudson River fish species.	Bull.Environ.Contam.Toxicol., 6		2021/04/06
魚類	Pimephales promelas		LC50	96	hours	5～45	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H. and C. Henderson	The acute toxicity of some heavy metals to different species of warmwater fishes	Air Wat. Pollut. Int. J. 10		2021/03/02
魚類	Lepomis macrochirus	mortality	LC50	48	hours	110	mg/L			12 ECHA Information on Registered Substances		US EPA study			2021/03/02
魚類	Lepomis macrochirus	mortality	LC50	24	hours	170	mg/L			12 ECHA Information on Registered Substances		US EPA study			2021/03/02
魚類	Pimephales promelas	mortality	LC50	120	hours	0.6	mg/L			12 ECHA Information on Registered Substances	Krzykwa JC, Saeid A, Jeffries MKS	Identifying sublethal endpoints for evaluating neurotoxic compounds utilizing the fish embryo toxicity test	Ecotoxicology and Environmental Safety 170		2021/03/02
魚類	Lepomis macrochirus	mortality	LC50	96	hours	60.3	mg/L			12 ECHA Information on Registered Substances		US EPA study			2021/03/02
魚類	Lepomis macrochirus	mortality	NOEC	96	hours	42	mg/L			12 ECHA Information on Registered Substances		US EPA study			2021/03/02
魚類	Carassius auratus (Goldfish)	mortality	LC50	24	hours	34.1	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H. and C. Henderson	The acute toxicity of some heavy metals to different species of warmwater fishes	Air Wat. Pollut. Int. J. 10		2021/03/02
魚類	Lepomis macrochirus	mortality	LC50	96	hours	5.36	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H. and C. Henderson	The acute toxicity of some heavy metals to different species of warmwater fishes	Air Wat. Pollut. Int. J. 10		2021/03/02
魚類	Carassius auratus (Goldfish)	mortality	LC50	48	hours	20.5	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H. and C. Henderson	The acute toxicity of some heavy metals to different species of warmwater fishes	Air Wat. Pollut. Int. J. 10		2021/03/02
魚類	Carassius auratus (Goldfish)	mortality	LC50	96	hours	9.82	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H. and C. Henderson	The acute toxicity of some heavy metals to different species of warmwater fishes	Air Wat. Pollut. Int. J. 10		2021/03/02
魚類	Lepomis macrochirus	mortality	LC50	24	hours	41.7	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H. and C. Henderson	The acute toxicity of some heavy metals to different species of warmwater fishes	Air Wat. Pollut. Int. J. 10		2021/03/02
魚類	Lepomis macrochirus	mortality	NOEC	96	hours	37	mg/L			12 ECHA Information on Registered Substances		US EPA study			2021/03/02
魚類	Lepomis macrochirus	mortality	LC50	96	hours	62.2	mg/L			12 ECHA Information on Registered Substances		US EPA study			2021/03/02
魚類	Lepomis macrochirus	mortality	LC50	48	hours	115	mg/L			12 ECHA Information on Registered Substances		US EPA study			2021/03/02
魚類	Lepomis macrochirus	mortality	LC50	24	hours	170	mg/L			12 ECHA Information on Registered Substances		US EPA study			2021/03/02
魚類	Fundulus heteroclitus (Mummichog)	mortality	LC50	96	hours	55.3	mg/L			12 ECHA Information on Registered Substances	Bielmyer GK, DeCarlo C, Morris C, and Carrigan T.	The influence of salinity on acute nickel toxicity to the two euryhaline fish species, Fundulus heteroclitus and Kryptolebias marmoratus.	Environmental Toxicology and Chemistry; 32(6)		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	24	hours	38.76	mg/L			12 ECHA Information on Registered Substances	Ghosh A, Kaviraj A, Saha S	Deposition, acute toxicity, and bioaccumulation of nickel in some freshwater organisms with best-fit functions modeling	Environ Sci Pollut Res 25		2021/03/02
魚類	Lepomis macrochirus	mortality	LC50	48	hours	82.1	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H. and C. Henderson	The acute toxicity of some heavy metals to different species of warmwater fishes	Air Wat. Pollut. Int. J. 10		2021/03/02
魚類	Fundulus heteroclitus (Mummichog)	mortality	LC50	96	hours	45.2	mg/L			12 ECHA Information on Registered Substances	Bielmyer GK, DeCarlo C, Morris C, and Carrigan T.	The influence of salinity on acute nickel toxicity to the two euryhaline fish species, Fundulus heteroclitus and Kryptolebias marmoratus.	Environmental Toxicology and Chemistry; 32(6)		2021/03/02
魚類	Fundulus heteroclitus (Mummichog)	mortality	LC50	96	hours	24.8	mg/L			12 ECHA Information on Registered Substances	Bielmyer GK, DeCarlo C, Morris C, and Carrigan T.	The influence of salinity on acute nickel toxicity to the two euryhaline fish species, Fundulus heteroclitus and Kryptolebias marmoratus.	Environmental Toxicology and Chemistry; 32(6)		2021/03/02
魚類	Fundulus heteroclitus (Mummichog)	mortality	LC50	96	hours	13.1	mg/L			12 ECHA Information on Registered Substances	Bielmyer GK, DeCarlo C, Morris C, and Carrigan T.	The influence of salinity on acute nickel toxicity to the two euryhaline fish species, Fundulus heteroclitus and Kryptolebias marmoratus.	Environmental Toxicology and Chemistry; 32(6)		2021/03/02
魚類	Fundulus heteroclitus (Mummichog)	mortality	LC50	96	hours	12.3	mg/L			12 ECHA Information on Registered Substances	Bielmyer GK, DeCarlo C, Morris C, and Carrigan T.	The influence of salinity on acute nickel toxicity to the two euryhaline fish species, Fundulus heteroclitus and Kryptolebias marmoratus.	Environmental Toxicology and Chemistry; 32(6)		2021/03/02
魚類	Lepomis macrochirus	mortality	LC50	96	hours	5.18	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H. and C. Henderson	The acute toxicity of some heavy metals to different species of warmwater fishes	Air Wat. Pollut. Int. J. 10		2021/03/02
魚類	Pimephales promelas	enzyme activities	NOEC	7	days	>=1.8	μmol nickel/g tissue			12 ECHA Information on Registered Substances		publication			2021/03/02
魚類	Lepomis macrochirus	mortality	LC50	24	hours	11.3	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H. and C. Henderson	The acute toxicity of some heavy metals to different species of warmwater fishes	Air Wat. Pollut. Int. J. 10		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	72	hours	8.46	mg/L			12 ECHA Information on Registered Substances	Blaylock, B.G. and M.L. Frank.	A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).	Bull. Environ. Contam. Toxicol. 21(4/5)		2021/03/02
魚類	Lepomis macrochirus	mortality	LC50	96	hours	39.6	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H. and C. Henderson	The acute toxicity of some heavy metals to different species of warmwater fishes	Air Wat. Pollut. Int. J. 10		2021/03/02
魚類	Pimephales promelas	number of eggs/spawning and hatchability	LOEC	7	days	0.73	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H.	Chronic toxicity of nickel to the fathead minnow	J. Water Pollut. Control Fed. 46(4)		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	96	hours	2.3	mg/L			12 ECHA Information on Registered Substances	Alam, M.K. and O.E. Maughan	The effect of malathion, diazinon, and various concentrations of zinc, copper, nickel, lead, iron, and mercury on fish	Biological Trace Element Research. 34		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	96	hours	1.64	mg/L			12 ECHA Information on Registered Substances	Alam, M.K. and O.E. Maughan	The effect of malathion, diazinon, and various concentrations of zinc, copper, nickel, lead, iron, and mercury on fish	Biological Trace Element Research. 34		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	96	hours	1.3	mg/L			12 ECHA Information on Registered Substances	Alam, M.K. and O.E. Maughan	The effect of malathion, diazinon, and various concentrations of zinc, copper, nickel, lead, iron, and mercury on fish	Biological Trace Element Research. 34		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	96	hours	1.54	mg/L			12 ECHA Information on Registered Substances	Alam, M.K. and O.E. Maughan	The effect of malathion, diazinon, and various concentrations of zinc, copper, nickel, lead, iron, and mercury on fish	Biological Trace Element Research. 34		2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	0.4	mg/L			12 ECHA Information on Registered Substances	Hoang, T.C., J.R. Tomasso, and S.J. Klaine	Influence of water quality and age on nickel toxicity to fathead minnows (Pimephales promelas)	Environ. Toxicol. Chem. Vol. 23, No. 1		2021/03/02
魚類	Carassius auratus (Goldfish)		LC50			2780	μg/L			12 ECHA Information on Registered Substances	Birge, W.J. and J.A. Black	Aquatic Toxicology of Nickel	In: Nickel in the Environment. J.O. Nriagu (ed.). Wiley. New York, NY.		2021/03/02
魚類	Carassius auratus (Goldfish)		LC10			414.4	μg/L			12 ECHA Information on Registered Substances	Birge, W.J. and J.A. Black	Aquatic Toxicology of Nickel	In: Nickel in the Environment. J.O. Nriagu (ed.). Wiley. New York, NY.		2021/03/02
魚類	Fundulus heteroclitus (Mummichog)	mortality	LC50	24	hours	>400	mg/L			12 ECHA Information on Registered Substances	Eisler, R. and R.J. Hennekey	Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna	Arch. Environ. Contam. Toxicol. 6		2021/03/02
魚類	Leuciscus idus (Orfe)	mortality	LC50			570	mg/L			12 ECHA Information on Registered Substances		other company data			2021/03/02
魚類	Pimephales promelas	mortality	LC50	96	hours	1.68	mg/L			12 ECHA Information on Registered Substances	Hoang, T.C., J.R. Tomasso, and S.J. Klaine	Influence of water quality and age on nickel toxicity to fathead minnows (Pimephales promelas)	Environ. Toxicol. Chem. Vol. 23, No. 1		2021/03/02
魚類	Pimephales promelas	survival, growth, and reproduction	NOEC	7	days	<=0.38	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H.	Chronic toxicity of nickel to the fathead minnow	J. Water Pollut. Control Fed. 46(4)		2021/03/02
魚類	Lepomis macrochirus	mortality	LC50	48	hours	15.9	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H. and C. Henderson	The acute toxicity of some heavy metals to different species of warmwater fishes	Air Wat. Pollut. Int. J. 10		2021/03/02
魚類	Pimephales promelas	mortality and terata and length	NOEC	32	days	0.057	mg/L			12 ECHA Information on Registered Substances	Birge, W.J., J.A. Black, J.F. Hobson, A.G. Westerman, and T.M. Short	Toxicological studies on aquatic contaminants originating from coal production and utilization: The induction of tolerance to silver in laboratory populations of fish and the chronic toxicity of nickel to fish early life stages.	Water Resources Research Institute. Kentucky University, Lexington, KY. Research Report No. 151.		2021/03/02
魚類	Pimephales promelas	mortality and terata	LOEC	32	days	0.12	mg/L			12 ECHA Information on Registered Substances	Birge, W.J., J.A. Black, J.F. Hobson, A.G. Westerman, and T.M. Short	Toxicological studies on aquatic contaminants originating from coal production and utilization: The induction of tolerance to silver in laboratory populations of fish and the chronic toxicity of nickel to fish early life stages.	Water Resources Research Institute. Kentucky University, Lexington, KY. Research Report No. 151.		2021/03/02
魚類	Pimephales promelas	mortality	NOEC	30	days	108.9	μg/L			12 ECHA Information on Registered Substances	Lind, D., K. Alto, and S. Chatterton.	Regional Copper-Nickel Study: Aquatic Toxicology Study.	Minnesota Environmental Quality Board		2021/03/02
魚類	Pimephales promelas	mortality	LOEC	30	days	433.5	μg/L			12 ECHA Information on Registered Substances	Lind, D., K. Alto, and S. Chatterton.	Regional Copper-Nickel Study: Aquatic Toxicology Study.	Minnesota Environmental Quality Board		2021/03/02
魚類	Poecilia reticulata (Guppy)	mortality	LC50	96	hours	15.62	mg/L			12 ECHA Information on Registered Substances	Shuhaimi-Othman M, Yakub N, Ramle N-A, and Abas A.	Comparative toxicity of eight metals on freshwater fish.	Toxicology and Industrial Health; DOI		2021/03/02
魚類	Poecilia reticulata (Guppy)	mortality	LC50	72	hours	18.72	mg/L			12 ECHA Information on Registered Substances	Shuhaimi-Othman M, Yakub N, Ramle N-A, and Abas A.	Comparative toxicity of eight metals on freshwater fish.	Toxicology and Industrial Health; DOI		2021/03/02
魚類	Pimephales promelas	mortality	LD50 (hard water)			27	mg/L			12 ECHA Information on Registered Substances		other company data			2021/03/02
魚類	Fundulus heteroclitus (Mummichog)		LC100	168	hours	250	mg/L			12 ECHA Information on Registered Substances	Eisler, R. and R.J. Hennekey	Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna	Arch. Environ. Contam. Toxicol. 6		2021/03/02
魚類	Lepomis macrochirus	mortality	LC50	48	hours	8.67	mg/L			12 ECHA Information on Registered Substances	Pickering, Q.H. and C. Henderson	The acute toxicity of some heavy metals to different species of warmwater fishes	Air Wat. Pollut. Int. J. 10		2021/03/02
魚類	Fundulus heteroclitus (Mummichog)	mortality	LC100	24	hours	>400	mg/L			12 ECHA Information on Registered Substances	Eisler, R. and R.J. Hennekey	Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna	Arch. Environ. Contam. Toxicol. 6		2021/03/02
魚類	Fundulus heteroclitus (Mummichog)	mortality	LC50	96	hours	6.98	mg/L			12 ECHA Information on Registered Substances	Bielmyer GK, DeCarlo C, Morris C, and Carrigan T.	The influence of salinity on acute nickel toxicity to the two euryhaline fish species, Fundulus heteroclitus and Kryptolebias marmoratus.	Environmental Toxicology and Chemistry; 32(6)		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	96	hours	6.16	mg/L			12 ECHA Information on Registered Substances	Blaylock, B.G. and M.L. Frank.	A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).	Bull. Environ. Contam. Toxicol. 21(4/5)		2021/03/02
魚類	Fundulus heteroclitus (Mummichog)		NOEC	168	hours	50	mg/L			12 ECHA Information on Registered Substances	Eisler, R. and R.J. Hennekey	Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna	Arch. Environ. Contam. Toxicol. 6		2021/03/02
魚類	Fundulus heteroclitus (Mummichog)		LC50	168	hours	150	mg/L			12 ECHA Information on Registered Substances	Eisler, R. and R.J. Hennekey	Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna	Arch. Environ. Contam. Toxicol. 6		2021/03/02
魚類	Fundulus heteroclitus (Mummichog)	mortality	NOEC	96	hours	250	mg/L			12 ECHA Information on Registered Substances	Eisler, R. and R.J. Hennekey	Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna	Arch. Environ. Contam. Toxicol. 6		2021/03/02
魚類	Fundulus heteroclitus (Mummichog)	mortality	LC100	96	hours	400	mg/L			12 ECHA Information on Registered Substances	Eisler, R. and R.J. Hennekey	Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna	Arch. Environ. Contam. Toxicol. 6		2021/03/02
魚類	Fundulus heteroclitus (Mummichog)	mortality	LC50	96	hours	350	mg/L			12 ECHA Information on Registered Substances	Eisler, R. and R.J. Hennekey	Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna	Arch. Environ. Contam. Toxicol. 6		2021/03/02
魚類	Fundulus heteroclitus (Mummichog)	mortality	NOEC	24	hours	400	mg/L			12 ECHA Information on Registered Substances	Eisler, R. and R.J. Hennekey	Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna	Arch. Environ. Contam. Toxicol. 6		2021/03/02
魚類	Fundulus heteroclitus (Mummichog)	mortality	LC50	96	hours	2.7	mg/L			12 ECHA Information on Registered Substances	Bielmyer GK, DeCarlo C, Morris C, and Carrigan T.	The influence of salinity on acute nickel toxicity to the two euryhaline fish species, Fundulus heteroclitus and Kryptolebias marmoratus.	Environmental Toxicology and Chemistry; 32(6)		2021/03/02
魚類	Cyprinodon variegatus (Sheepshead minnow)	survival and growth (dry weight)	LOEC	28	days	40.6	mgNi/L			12 ECHA Information on Registered Substances	DeForest DK, Schlekat CE.	Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.	Integr Environ Assess Manag. 2013 Oct;9(4)		2021/03/02
魚類	Cyprinodon variegatus (Sheepshead minnow)	growth (dry weight)	IC20	28	days	23.5	mgNi/L			12 ECHA Information on Registered Substances	DeForest DK, Schlekat CE.	Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.	Integr Environ Assess Manag. 2013 Oct;9(4)		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	233	hours	1.3	mg/L			12 ECHA Information on Registered Substances	Blaylock, B.G. and M.L. Frank.	A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).	Bull. Environ. Contam. Toxicol. 21(4/5)		2021/03/02
魚類	Cyprinodon variegatus (Sheepshead minnow)	survival or growth (dry weight)	NOEC	28	days	21.7	mgNi/L			12 ECHA Information on Registered Substances	DeForest DK, Schlekat CE.	Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.	Integr Environ Assess Manag. 2013 Oct;9(4)		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	212	hours	2.14	mg/L			12 ECHA Information on Registered Substances	Blaylock, B.G. and M.L. Frank.	A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).	Bull. Environ. Contam. Toxicol. 21(4/5)		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	184	hours	3.18	mg/L			12 ECHA Information on Registered Substances	Blaylock, B.G. and M.L. Frank.	A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).	Bull. Environ. Contam. Toxicol. 21(4/5)		2021/03/02
魚類	Cyprinus carpio (Carp)	mortality	LC50	257	hours	0.75	mg/L			12 ECHA Information on Registered Substances	Blaylock, B.G. and M.L. Frank.	A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).	Bull. Environ. Contam. Toxicol. 21(4/5)		2021/03/02
魚類	Cyprinodon variegatus (Sheepshead minnow)	mortality	LC50	28	days	27.8	mgNi/L			12 ECHA Information on Registered Substances	DeForest DK, Schlekat CE.	Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.	Integr Environ Assess Manag. 2013 Oct;9(4)		2021/03/02
魚類	Cyprinodon variegatus (Sheepshead minnow)	growth (dry weight)	IC50	28	days	29.9	mgNi/L			12 ECHA Information on Registered Substances	DeForest DK, Schlekat CE.	Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.	Integr Environ Assess Manag. 2013 Oct;9(4)		2021/03/02
魚類	Cyprinodon variegatus (Sheepshead minnow)	growth (dry weight)	EC10	28	days	20.76	mgNi/L			12 ECHA Information on Registered Substances	DeForest DK, Schlekat CE.	Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.	Integr Environ Assess Manag. 2013 Oct;9(4)		2021/03/02
魚類	Pimephales promelas	mortality	LC50	7	days	0.7	mg/L			12 ECHA Information on Registered Substances	Krzykwa JC, Saeid A, Jeffries MKS	Identifying sublethal endpoints for evaluating neurotoxic compounds utilizing the fish embryo toxicity test	Ecotoxicology and Environmental Safety 170		2021/03/02
魚類	Pimephales promelas	time to hatch	LOEC	21	days	<=24.8	μg/L	○		12 ECHA Information on Registered Substances		publication			2021/03/02
魚類	Cyprinodon variegatus (Sheepshead minnow)	mortality	LC20	28	days	23.9	mgNi/L			12 ECHA Information on Registered Substances	DeForest DK, Schlekat CE.	Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.	Integr Environ Assess Manag. 2013 Oct;9(4)		2021/03/02

生物種

学名

影響内容

エンドポイント

暴露期間(値)

暴露期間(単位)

毒性値

毒性値(単位)

Read-across *

QSAR

GLP

設定濃度

実測濃度

情報源

情報源による信頼性評価

著者

タイトル

記載誌

発行年

情報更新日

subject type

scientific name

effect

endpoint

exposure duration value

exposure duration unit

toxicity value

toxicity unit

Read-across

QSAR

GLP

nominal concentration

measured concentration

original work type

original work reliability rank

author

title

referenced journal

publication year

Information update date

藻類

Navicula pelliculosa

growth rate

EC30

days

0.8

μmol/L

12 ECHA Information on Registered Substances

Nagai T, De Schamphelaere KA.

The effect of binary mixtures of zinc, copper, cadmium, and nickel on the growth of the freshwater diatom Navicula pelliculosa and comparison with mixture toxicity model predictions.

Environ Toxicol Chem. 2016 Nov;35(11)

2021/03/02

藻類

Navicula pelliculosa

growth rate

EC10/4

days

0.15

μmol/L

12 ECHA Information on Registered Substances

Nagai T, De Schamphelaere KA.

The effect of binary mixtures of zinc, copper, cadmium, and nickel on the growth of the freshwater diatom Navicula pelliculosa and comparison with mixture toxicity model predictions.

Environ Toxicol Chem. 2016 Nov;35(11)

2021/03/02

藻類

Scenedesmus quadricauda

toxic threshold

days

1.3

mg/L

12 ECHA Information on Registered Substances

Bringmann G. and R. Kuhn

Comparison of the toxicity thresholds of water pollutants to bacteria, algae, and protozoa in the cell multiplication inhibition test

Water Res. 14

2021/03/02

藻類

Chlorella vulgaris

growth rate

EC15

days

1.9

mg/L

12 ECHA Information on Registered Substances

Rugnini L, Costa G, Congestri R, Bruno L

Testing of two different strains of green microalgae for Cu and Ni removal from aqueous media

Science of the Total Environment 601–602

2021/03/02

藻類

Chlorella vulgaris

growth rate

EC22

days

5.7

mg/L

12 ECHA Information on Registered Substances

Rugnini L, Costa G, Congestri R, Bruno L

Testing of two different strains of green microalgae for Cu and Ni removal from aqueous media

Science of the Total Environment 601–602

2021/03/02

藻類

Chlorella vulgaris

growth rate

EC25

days

11.4

mg/L

12 ECHA Information on Registered Substances

Rugnini L, Costa G, Congestri R, Bruno L

Testing of two different strains of green microalgae for Cu and Ni removal from aqueous media

Science of the Total Environment 601–602

2021/03/02

藻類

Scenedesmus quadricauda

not reported

"Toxic"

>=1.3

mg/L

12 ECHA Information on Registered Substances

other company data

2021/03/02

藻類

Navicula pelliculosa

growth rate

EC70

days

1.11

μmol/L

12 ECHA Information on Registered Substances

Nagai T, De Schamphelaere KA.

The effect of binary mixtures of zinc, copper, cadmium, and nickel on the growth of the freshwater diatom Navicula pelliculosa and comparison with mixture toxicity model predictions.

Environ Toxicol Chem. 2016 Nov;35(11)

2021/03/02

藻類

Navicula pelliculosa

growth rate

EC10/2

days

0.31

μmol/L

12 ECHA Information on Registered Substances

Nagai T, De Schamphelaere KA.

The effect of binary mixtures of zinc, copper, cadmium, and nickel on the growth of the freshwater diatom Navicula pelliculosa and comparison with mixture toxicity model predictions.

Environ Toxicol Chem. 2016 Nov;35(11)

2021/03/02

藻類

Dunaliella tertiolecta

Average Yield

IC20

hours

13397.9

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

藻類

Dunaliella tertiolecta

Average Area Under Growth Curve

IC20

hours

13800.9

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

藻類

Dunaliella tertiolecta

Average Specific Growth Rate

IC20

hours

27481.8

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

藻類

Navicula pelliculosa

Population

days

100

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Fezy,J.S., D.F. Spencer, and R.W. Greene

The Effect of Nickel on the Growth of the Freshwater Diatom Navicula pelliculosa

Environ. Pollut.20(2): 131-137

1979

2016/03/25

藻類

Anabaena flos-aquae

Population

days

301

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Spencer,D.F., and R.W. Greene

Effects of Nickel on Seven Species of Freshwater Algae

Environ. Pollut. A.25(4): 241-247

1981

2016/03/25

藻類

Navicula pelliculosa

Population

days

100

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Fezy,J.S., D.F. Spencer, and R.W. Greene

The Effect of Nickel on the Growth of the Freshwater Diatom Navicula pelliculosa

Environ. Pollut.20(2): 131-137

1979

2016/03/25

藻類

Chlorella vulgaris

Population

NOEC

6.9

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

De Jong,L.E.D.

Tolerance of Chlorella vulgaris for Metallic and Non-Metallic Ions

Antonie van Leeuwenhoek (Gedrukt)31:301-313

1965

2016/03/25

藻類

Chlorella vulgaris

Population

LOEC

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

De Jong,L.E.D.

Tolerance of Chlorella vulgaris for Metallic and Non-Metallic Ions

Antonie van Leeuwenhoek (Gedrukt)31:301-313

1965

2016/03/25

藻類

Anabaena flos-aquae

Population

days

602

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Spencer,D.F., and R.W. Greene

Effects of Nickel on Seven Species of Freshwater Algae

Environ. Pollut. A.25(4): 241-247

1981

2016/03/25

藻類

Chlorella vulgaris

Population

LOEC

121.76

days

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

De Jong,L.E.D.

Tolerance of Chlorella vulgaris for Metallic and Non-Metallic Ions

Antonie van Leeuwenhoek (Gedrukt)31:301-313

1965

2017/03/23

藻類

Chlorella vulgaris

Population

NOEC

121.76

days

6.9

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

De Jong,L.E.D.

Tolerance of Chlorella vulgaris for Metallic and Non-Metallic Ions

Antonie van Leeuwenhoek (Gedrukt)31:301-313

1965

2017/03/23

藻類

Chlorella sp.

growth rate

EC50

hours

663

μg/L

12 ECHA Information on Registered Substances

Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R

Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters

Environmental Toxicology and Chemistry. 37 (10)

2021/03/02

藻類

Chlorella sp.

growth rate

EC50

hours

826

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

藻類

Scenedesmus quadricauda

growth rate

EC50

days

0.6

mg/L

12 ECHA Information on Registered Substances

Fargasova, A.

Interactive effect of manganese, molybdenum, nickel, copper I and II, and vanadium on the freshwater alga Scenedesmus quadricauda.

Bull. Environ. Contam. Toxicol. 67

2021/03/02

藻類

Scenedesmus quadricauda

Chlorophyll-b inhibition

EC50

days

0.39

mg/L

12 ECHA Information on Registered Substances

Fargasova, A., A. Bumbalova, and E. Havranek.

Ecotoxicological effect and uptake of metals (Cu+, Cu2+, Mn2+, Mo6+, Ni2+, V5+) in freshwater alga Scenedesmus quadricauda.

Chemosphere. 38(5)

2021/03/02

藻類

Scenedesmus quadricauda

Chlorophyll-a inhibition

EC50

days

0.57

mg/L

12 ECHA Information on Registered Substances

Fargasova, A., A. Bumbalova, and E. Havranek.

Ecotoxicological effect and uptake of metals (Cu+, Cu2+, Mn2+, Mo6+, Ni2+, V5+) in freshwater alga Scenedesmus quadricauda.

Chemosphere. 38(5)

2021/03/02

藻類

Navicula pelliculosa

growth rate

EC50

days

0.94

μmol/L

12 ECHA Information on Registered Substances

Nagai T, De Schamphelaere KA.

The effect of binary mixtures of zinc, copper, cadmium, and nickel on the growth of the freshwater diatom Navicula pelliculosa and comparison with mixture toxicity model predictions.

Environ Toxicol Chem. 2016 Nov;35(11)

2021/03/02

藻類

Chlorella sp.

growth rate

EC50

hours

1430

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

藻類

Scenedesmus quadricauda

Total Chlorophyll inhibition

EC50

days

0.44

mg/L

12 ECHA Information on Registered Substances

Fargasova, A., A. Bumbalova, and E. Havranek.

Ecotoxicological effect and uptake of metals (Cu+, Cu2+, Mn2+, Mo6+, Ni2+, V5+) in freshwater alga Scenedesmus quadricauda.

Chemosphere. 38(5)

2021/03/02

藻類

Chlorella sp.

growth rate

EC50

hours

282

μg/L

12 ECHA Information on Registered Substances

Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R

Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters

Environmental Toxicology and Chemistry. 37 (10)

2021/03/02

藻類

Chlorella pyrenoidosa

growth rate

EC50

hours

0.41

mg/L

12 ECHA Information on Registered Substances

Lin, K.C., Y.L. Lee, and C.Y. Chen

Metal toxicity to Chlorella pyrenoidosa assessed by a short-term continuous test

Journal of Hazardous Materials 142

2021/03/02

藻類

Chlorella sp.

growth rate

EC50

hours

434

μg/L

12 ECHA Information on Registered Substances

Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R

Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters

Environmental Toxicology and Chemistry. 37 (10)

2021/03/02

藻類

Chlorella sp.

growth rate

EC50

hours

2413

μg/L

12 ECHA Information on Registered Substances

Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R

Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters

Environmental Toxicology and Chemistry. 37 (10)

2021/03/02

藻類

Scenedesmus acutus

growth rate

EC50

hours

33.3

mg/L

12 ECHA Information on Registered Substances

Azeez, P.A. and D.K. Banerjee.

Nickel uptake and toxicity in cyanobacteria.

Toxicological and environmental chemistry

2021/03/02

藻類

Scenedesmus acutus

growth rate

EC50

120

hours

16.5

mg/L

12 ECHA Information on Registered Substances

Azeez, P.A. and D.K. Banerjee.

Nickel uptake and toxicity in cyanobacteria.

Toxicological and environmental chemistry

2021/03/02

藻類

Scenedesmus acutus

growth rate

EC50

144

hours

9.07

mg/L

12 ECHA Information on Registered Substances

Azeez, P.A. and D.K. Banerjee.

Nickel uptake and toxicity in cyanobacteria.

Toxicological and environmental chemistry

2021/03/02

藻類

Scenedesmus acutus

growth rate

EC50

168

hours

8.34

mg/L

12 ECHA Information on Registered Substances

Azeez, P.A. and D.K. Banerjee.

Nickel uptake and toxicity in cyanobacteria.

Toxicological and environmental chemistry

2021/03/02

藻類

Scenedesmus quadricauda

growth rate

EC50

days

0.58

mg/L

12 ECHA Information on Registered Substances

Fargasova, A., A. Bumbalova, and E. Havranek.

Ecotoxicological effect and uptake of metals (Cu+, Cu2+, Mn2+, Mo6+, Ni2+, V5+) in freshwater alga Scenedesmus quadricauda.

Chemosphere. 38(5)

2021/03/02

藻類

Chlorella sp.

growth rate

EC50

hours

853

μg/L

12 ECHA Information on Registered Substances

Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R

Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters

Environmental Toxicology and Chemistry. 37 (10)

2021/03/02

藻類

Anabaena flos-aquae

growth rate

LOEC

days

600

μg/L

12 ECHA Information on Registered Substances

Spencer, D.F. and R.W. Greene.

Effects of nickel on seven species of freshwater algae.

Environ. Pollut. (Series A). 25(4)

2021/03/02

藻類

Anabaena flos-aquae

growth rate

NOEC

days

300

μg/L

12 ECHA Information on Registered Substances

Spencer, D.F. and R.W. Greene.

Effects of nickel on seven species of freshwater algae.

Environ. Pollut. (Series A). 25(4)

2021/03/02

藻類

Chlorella sp.

growth rate

EC10

hours

896

μg/L

12 ECHA Information on Registered Substances

Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R

Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters

Environmental Toxicology and Chemistry. 37 (10)

2021/03/02

藻類

Dunaliella tertiolecta

Average Yield, Average Area Under Growth Cu

NOEC

hours

5476.8

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

藻類

Dunaliella tertiolecta

Average Yield, Average Area Under Growth Cu

LOEC

hours

11551.3

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

藻類

Chlorella sp.

growth rate

EC10

hours

90.5

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

藻類

Chlorella sp.

growth rate

EC10

hours

64.7

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

藻類

Skeletonema costatum

Average Specific Growth Rate

EC10

hours

661.3

μg/L

12 ECHA Information on Registered Substances

DeForest DK, Schlekat CE.

Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.

Integr Environ Assess Manag. 2013 Oct;9(4)

2021/03/02

藻類

Chlorella sp.

growth rate

LOEC

hours

97.7

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

藻類

Chlorella sp.

growth rate

NOEC

hours

98.2

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

藻類

Skeletonema costatum

Average Specific Growth Rate

EC10

hours

190.6

μg/L

12 ECHA Information on Registered Substances

DeForest DK, Schlekat CE.

Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.

Integr Environ Assess Manag. 2013 Oct;9(4)

2021/03/02

藻類

Chlorella sp.

growth rate

NOEC

hours

<97.7

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

藻類

Chlorella sp.

growth rate

LOEC

hours

168

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

藻類

Skeletonema costatum

Average Specific Growth Rate

EC10

hours

265.4

μg/L

12 ECHA Information on Registered Substances

DeForest DK, Schlekat CE.

Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.

Integr Environ Assess Manag. 2013 Oct;9(4)

2021/03/02

藻類

Scenedesmus quadricauda

nitrate reductase activity, alkaline phosph

NOEC

days

<1.1

μM

12 ECHA Information on Registered Substances

publication

2021/03/02

藻類

Chlorella vulgaris

other: nitrate reductase activity

LOEC

days

3.2

μmol/L

12 ECHA Information on Registered Substances

publication

2021/03/02

藻類

Chlorella vulgaris

other: nitrate reductase activity, alkaline

NOEC

days

<3.2

μmol/L

12 ECHA Information on Registered Substances

publication

2021/03/02

藻類

Skeletonema costatum

Average Specific Growth Rate

EC10

hours

773.4

μg/L

12 ECHA Information on Registered Substances

DeForest DK, Schlekat CE.

Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.

Integr Environ Assess Manag. 2013 Oct;9(4)

2021/03/02

藻類

Navicula pelliculosa

growth rate

EC10

days

0.61

μmol/L

12 ECHA Information on Registered Substances

Nagai T, De Schamphelaere KA.

The effect of binary mixtures of zinc, copper, cadmium, and nickel on the growth of the freshwater diatom Navicula pelliculosa and comparison with mixture toxicity model predictions.

Environ Toxicol Chem. 2016 Nov;35(11)

2021/03/02

藻類

Chlorella sp.

growth rate

EC10

hours

148

μg/L

12 ECHA Information on Registered Substances

Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R

Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters

Environmental Toxicology and Chemistry. 37 (10)

2021/03/02

藻類

Chlorella sp.

growth rate

EC10

hours

μg/L

12 ECHA Information on Registered Substances

Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R

Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters

Environmental Toxicology and Chemistry. 37 (10)

2021/03/02

藻類

Scenedesmus quadricauda

nitrate reductase activity, alkaline phosph

LOEC

days

1.1

μM

12 ECHA Information on Registered Substances

publication

2021/03/02

藻類

Chlorella vulgaris

Growth

LOEC

months

μg/L

16 ECOTOX

De Jong,L.E.D.

Tolerance of Chlorella vulgaris for Metallic and Non-Metallic Ions

Antonie van Leeuwenhoek (Gedrukt)31

2020/11/12

藻類

Anabaena cylindrica

growth rate

NOEC

days

600

μg/L

12 ECHA Information on Registered Substances

Spencer, D.F. and R.W. Greene.

Effects of nickel on seven species of freshwater algae.

Environ. Pollut. (Series A). 25(4)

2021/03/02

藻類

Anabaena cylindrica

growth rate

LOEC

days

>600

μg/L

12 ECHA Information on Registered Substances

Spencer, D.F. and R.W. Greene.

Effects of nickel on seven species of freshwater algae.

Environ. Pollut. (Series A). 25(4)

2021/03/02

藻類

Chlorella sp.

growth rate

EC10

hours

122

μg/L

12 ECHA Information on Registered Substances

Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R

Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters

Environmental Toxicology and Chemistry. 37 (10)

2021/03/02

藻類

Chlorella vulgaris

Growth

NOEC

months

6.9

μg/L

16 ECOTOX

De Jong,L.E.D.

Tolerance of Chlorella vulgaris for Metallic and Non-Metallic Ions

Antonie van Leeuwenhoek (Gedrukt)31

2020/11/12

藻類

Chlorella sp.

growth rate

EC10

hours

278

μg/L

12 ECHA Information on Registered Substances

Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R

Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters

Environmental Toxicology and Chemistry. 37 (10)

2021/03/02

藻類

Scenedesmus quadricauda

growth rate

LOEC

days

100

μg/L

12 ECHA Information on Registered Substances

Spencer, D.F. and R.W. Greene.

Effects of nickel on seven species of freshwater algae.

Environ. Pollut. (Series A). 25(4)

2021/03/02

藻類

Navicula pelliculosa

growth rate

LOEC

days

<100

μg/L

12 ECHA Information on Registered Substances

Fezy, J.S., D.F. Spencer, and R.W. Greene.

The effect of nickel on the growth of the freshwater diatom Navicula pelliculosa.

Environ. Pollut. 20(3)

2021/03/02

藻類

Dunaliella tertiolecta

Average Yield

IC10

hours

8585.6

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

藻類

Dunaliella tertiolecta

Average Area Under Growth Curve

IC10

hours

8574.1

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

藻類

Skeletonema costatum

Average Specific Growth Rate

EC10

hours

122.7

μg/L

12 ECHA Information on Registered Substances

DeForest DK, Schlekat CE.

Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.

Integr Environ Assess Manag. 2013 Oct;9(4)

2021/03/02

藻類

Dunaliella tertiolecta

Average Specific Growth Rate

IC10

hours

17891.1

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

藻類

Scenedesmus quadricauda

growth rate

LOEC

days

<100

μg/L

12 ECHA Information on Registered Substances

Spencer, D.F. and R.W. Greene.

Effects of nickel on seven species of freshwater algae.

Environ. Pollut. (Series A). 25(4)

2021/03/02

藻類

Navicula pelliculosa

growth rate

LOEC

days

100

μg/L

12 ECHA Information on Registered Substances

Fezy, J.S., D.F. Spencer, and R.W. Greene.

The effect of nickel on the growth of the freshwater diatom Navicula pelliculosa.

Environ. Pollut. 20(3)

2021/03/02

甲殻類

Chironomus riparius

Mortality

LC50

hours

150000

μg/L

16 ECOTOX

Powlesland,C., and J. George

Acute and Chronic Toxicity of Nickel to Larvae of Chironomus riparis (Meigen)

Environ. Pollut. A.42(1)

2020/11/12

甲殻類

Chironomus riparius

Mortality

LC50

hours

184000

μg/L

16 ECOTOX

Powlesland,C., and J. George

Acute and Chronic Toxicity of Nickel to Larvae of Chironomus riparis (Meigen)

Environ. Pollut. A.42(1)

2020/11/12

甲殻類

Chironomus dilutus

Population//Abundance

NOEC

days

91.33

μg/L

3.80 ug/L / 91.33 ug/L

16 ECOTOX

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462)

2020/11/12

甲殻類

Chironomus riparius

Mortality

LC50

hours

81300

μg/L

16 ECOTOX

Powlesland,C., and J. George

Acute and Chronic Toxicity of Nickel to Larvae of Chironomus riparis (Meigen)

Environ. Pollut. A.42(1)

2020/11/12

甲殻類

Chironomus riparius

Mortality

LC50

hours

72400

μg/L

16 ECOTOX

Powlesland,C., and J. George

Acute and Chronic Toxicity of Nickel to Larvae of Chironomus riparis (Meigen)

Environ. Pollut. A.42(1)

2020/11/12

甲殻類

Chironomus riparius

Mortality

LC50

hours

174000

μg/L

16 ECOTOX

Powlesland,C., and J. George

Acute and Chronic Toxicity of Nickel to Larvae of Chironomus riparis (Meigen)

Environ. Pollut. A.42(1)

2020/11/12

甲殻類

Chironomus riparius

Mortality

NR-LETH

days

13900

μg/L

16 ECOTOX

Powlesland,C., and J. George

Acute and Chronic Toxicity of Nickel to Larvae of Chironomus riparis (Meigen)

Environ. Pollut. A.42(1)

2020/11/12

甲殻類

Chironomus riparius

Mortality

LC50

hours

84900

μg/L

16 ECOTOX

Powlesland,C., and J. George

Acute and Chronic Toxicity of Nickel to Larvae of Chironomus riparis (Meigen)

Environ. Pollut. A.42(1)

2020/11/12

甲殻類

Daphnia magna

Mortality

LD50

days

6000

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Tomasik,P., C.H.D. Magadza, S. Mhizha, and A. Chirume

The Metal-Metal Interactions in Biological Systems. Part III. Daphnia magna

Water Air Soil Pollut.82:695-711

1995

2016/03/25

甲殻類

Ceriodaphnia dubia

Mortality

days

3.8

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Kszos,L.A., A.J. Stewart, and P.A. Taylor

An Evaluation of Nickel Toxicity to Ceriodaphnia dubia and Daphnia magna in a Contaminated Stream and in Laboratory Tests

Environ. Toxicol. Chem.11(7): 1001-1012

1992

2016/03/25

甲殻類

Ceriodaphnia dubia

Reproduction

days

3.8

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Kszos,L.A., A.J. Stewart, and P.A. Taylor

An Evaluation of Nickel Toxicity to Ceriodaphnia dubia and Daphnia magna in a Contaminated Stream and in Laboratory Tests

Environ. Toxicol. Chem.11(7): 1001-1012

1992

2016/03/25

甲殻類

Daphnia magna

Mortality

LD50

days

11000

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Tomasik,P., C.H.D. Magadza, S. Mhizha, and A. Chirume

The Metal-Metal Interactions in Biological Systems. Part III. Daphnia magna

Water Air Soil Pollut.82:695-711

1995

2016/03/25

甲殻類

Daphnia magna

Mortality

LC50

days

915

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Call,D.J., L.T. Brooke, N. Ahmad, and J.E. Richter

Toxicity and Metabolism Studies with EPA (Environmental Protection Agency) Priority Pollutants and Related Chemicals in Freshwater Organisms

EPA 600/3-83-095, U.S.EPA, Duluth, MN:120 p.

1983

2016/03/25

甲殻類

Ceriodaphnia dubia

Mortality

days

7.5

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Kszos,L.A., A.J. Stewart, and P.A. Taylor

An Evaluation of Nickel Toxicity to Ceriodaphnia dubia and Daphnia magna in a Contaminated Stream and in Laboratory Tests

Environ. Toxicol. Chem.11(7): 1001-1012

1992

2016/03/25

甲殻類

Ceriodaphnia dubia

Mortality

days

7.5

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Kszos,L.A., A.J. Stewart, and P.A. Taylor

An Evaluation of Nickel Toxicity to Ceriodaphnia dubia and Daphnia magna in a Contaminated Stream and in Laboratory Tests

Environ. Toxicol. Chem.11(7): 1001-1012

1992

2017/03/15

甲殻類

Daphnia magna

Mortality

LC50

days

915

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Call,D.J., L.T. Brooke, N. Ahmad, and J.E. Richter

Toxicity and Metabolism Studies with EPA (Environmental Protection Agency) Priority Pollutants and Related Chemicals in Freshwater Organisms

EPA 600/3-83-095, U.S.EPA, Duluth, MN:120 p.

1983

2017/03/15

甲殻類

Daphnia magna

immobilisation

EC50

hours

3.85

mg/L

12 ECHA Information on Registered Substances

Kim D, Chae Y, An Y-J

Mixture Toxicity of Nickel and Microplastics with Different Functional Groups on Daphnia magna

Environmental Science and Technology. 51

2021/03/02

甲殻類

Daphnia magna

mortality

LC20

hours

1036.7

μg/L

12 ECHA Information on Registered Substances

Lari E, Gauthier P, Mohaddes E, Pyle GG

Interactive toxicity of Ni, Zn, Cu, and Cd on Daphnia magna at lethal and sub-lethal concentrations

Journal of Hazardous Materials 334

2021/03/02

甲殻類

Daphnia magna

feeding inhibition

EC50

hours

2.41

mg/L

○

12 ECHA Information on Registered Substances

publication

2021/03/02

甲殻類

Daphnia magna

mortality

LC50

hours

1502.5

μg/L

12 ECHA Information on Registered Substances

Lari E, Gauthier P, Mohaddes E, Pyle GG

Interactive toxicity of Ni, Zn, Cu, and Cd on Daphnia magna at lethal and sub-lethal concentrations

Journal of Hazardous Materials 334

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

27.6

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

296

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC10

hours

86.8

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC10

hours

88.9

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

598

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC10

hours

125

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

214.1

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC10

hours

122

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

94.3

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

μg/L

12 ECHA Information on Registered Substances

Schubauer-Berigan, M.K., J.R. Dierkes, P.D. Monson, and G.T. Ankley

pH-Dependent toxicity of Cd, Cu, Ni, Pb and Zn to Ceriodaphnia dubia, Pimephales Promelas, Hyalella azteca and Lumbriculus variegates

Environmental Toxicology and Chemistry. 12

2021/03/02

甲殻類

Daphnia magna

mortality

LC50

hours

10.9

mg/L

12 ECHA Information on Registered Substances

Khangarot, B.S. and P.K. Ray

Investigation of correlation between physicochemical properties of metals and their toxicity to the water flea Daphnia magna Straus

Ecotoxicology and Environmental Safety. 18

2021/03/02

甲殻類

Daphnia magna

immobilization

EC50

hours

>=0.86～<=6.3

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

82.1

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

593

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

mortality

LC50

hours

510

μg/L

12 ECHA Information on Registered Substances

Biesinger, K.E. and G.M. Christensen

Effects of various metals on survival, growth, reproduction, and metabolism of Daphnia magna

Journal of Fisheries Research Board of Canada. 29(12)

2021/03/02

甲殻類

Daphnia magna

mortality

NOEC

hours

mg/L

12 ECHA Information on Registered Substances

Bozich J, Hang M, Hamers R, Klaper R

Core chemistry influences the toxicity of multicomponent metal oxide nanomaterials, lithium nickel manganese cobalt oxide, and lithium cobalt oxide to Daphnia magna

Environ Toxicol Chem; 36(9)

2021/03/02

甲殻類

Daphnia pulex

mortality

LC50

hours

7.5

μmol/L

12 ECHA Information on Registered Substances

Leonard EM, Wood CM

Acute toxicity, critical body residues, Michaelis-Menten analysis of bioaccumulation, and ionoregulatory disturbance in response to waterborne nickel in four invertebrates: Chironomus riparius, Lymnaea stagnalis, Lumbriculus variegatus and Daphnia pulex

Comparative Biochemistry and Physiology, Part C 158

2021/03/02

甲殻類

Daphnia magna

LC50

hours

627

mg/L

12 ECHA Information on Registered Substances

government document

2021/03/02

甲殻類

Daphnia magna

LC50

hours

645

mg/L

12 ECHA Information on Registered Substances

government document

2021/03/02

甲殻類

Daphnia magna

LC50

hours

1800

mg/L

12 ECHA Information on Registered Substances

government document

2021/03/02

甲殻類

Daphnia magna

LC50

hours

1810

mg/L

12 ECHA Information on Registered Substances

government document

2021/03/02

甲殻類

Daphnia magna

immobilization

EC50

hours

70.8

μM

12 ECHA Information on Registered Substances

publication

2021/03/02

甲殻類

Daphnia magna

mortality

LC75

hours

2150

μg/L

○

12 ECHA Information on Registered Substances

publication

2021/03/02

甲殻類

Daphnia magna

mobility

EC50

hours

11.77

mg/L

12 ECHA Information on Registered Substances

Sivula L, Vehniainen E-R, Karjalainen AK, Kukkonen JVK

Toxicity of biomining effluents to Daphnia magna: Acute toxicity and transcriptomic biomarkers

Chemosphere, 210

2021/03/02

甲殻類

Daphnia magna

LC50

hours

3.2

mg/L

12 ECHA Information on Registered Substances

Ewell, W.S., J.W. Gorsuch, R.O. Kringle, K.A. Robillard, and R.C. Spiegel

Simultaneous evaluation of the acute effects of chemicals on seven aquatic species

Environmental Toxicology and Chemistry. 5

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

74.4

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

297

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

133.1

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

mortality

LC50

hours

7.59

mg/L

12 ECHA Information on Registered Substances

Khangarot, B.S. and P.K. Ray

Investigation of correlation between physicochemical properties of metals and their toxicity to the water flea Daphnia magna Straus

Ecotoxicology and Environmental Safety. 18

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

94.3

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia pulex

mortality

LC50

hours

μmol/L

12 ECHA Information on Registered Substances

Leonard EM, Wood CM

Comparative Biochemistry and Physiology, Part C 158

2021/03/02

甲殻類

Daphnia magna

NOEC

hours

1.8

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

mortality

EC50

hours

6.68

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

266.3

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

202.3

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

111.1

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

mortality

LC50

hours

0.915

mg/L

12 ECHA Information on Registered Substances

Call, D.J., L.T. Brooke, N. Ahmad, and J.E. Richter.

Toxicity and metabolism studies with EPA priority pollutants and related chemicals in freshwater organisms.

PB83-263665/EPA-600/3-83-095. National Technical Information Service (NTIS). Springfield, VA.

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

87.5

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

107.3

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

mortality

LC50

hours

1120

μg/L

12 ECHA Information on Registered Substances

Biesinger, K.E. and G.M. Christensen

Effects of various metals on survival, growth, reproduction, and metabolism of Daphnia magna

Journal of Fisheries Research Board of Canada. 29(12)

2021/03/02

甲殻類

Daphnia magna

EC50

hours

9.48

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

111.1

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia pulicaria

mortality

LC50

hours

1813

μg/L

12 ECHA Information on Registered Substances

Lind, D., K. Alto, and S. Chatterton.

Regional Copper-Nickel Study: Aquatic Toxicology Study.

Minnesota Environmental Quality Board

2021/03/02

甲殻類

Daphnia magna

LC50

hours

10.1

mg/L

12 ECHA Information on Registered Substances

Van Sprang, P.A. and C.R. Janssen.

Toxicity identification of metals: Development of toxicity identification fingerprints.

Environmental Toxicology and Chemistry. 20(11)

2021/03/02

甲殻類

Daphnia magna

feeding inhibition

EC50

hours

2.74

mg/L

○

12 ECHA Information on Registered Substances

publication

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

27.6

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

NOEC

hours

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia pulicaria

mortality

LC50

hours

2171

μg/L

12 ECHA Information on Registered Substances

Lind, D., K. Alto, and S. Chatterton.

Regional Copper-Nickel Study: Aquatic Toxicology Study.

Minnesota Environmental Quality Board

2021/03/02

甲殻類

Daphnia pulicaria

mortality

LC50

hours

3757

μg/L

12 ECHA Information on Registered Substances

Lind, D., K. Alto, and S. Chatterton.

Regional Copper-Nickel Study: Aquatic Toxicology Study.

Minnesota Environmental Quality Board

2021/03/02

甲殻類

Daphnia pulicaria

mortality

LC50

hours

3414

μg/L

12 ECHA Information on Registered Substances

Lind, D., K. Alto, and S. Chatterton.

Regional Copper-Nickel Study: Aquatic Toxicology Study.

Minnesota Environmental Quality Board

2021/03/02

甲殻類

Daphnia pulicaria

mortality

LC50

hours

2325

μg/L

12 ECHA Information on Registered Substances

Lind, D., K. Alto, and S. Chatterton.

Regional Copper-Nickel Study: Aquatic Toxicology Study.

Minnesota Environmental Quality Board

2021/03/02

甲殻類

Daphnia pulicaria

mortality

LC50

hours

3014

μg/L

12 ECHA Information on Registered Substances

Lind, D., K. Alto, and S. Chatterton.

Regional Copper-Nickel Study: Aquatic Toxicology Study.

Minnesota Environmental Quality Board

2021/03/02

甲殻類

Daphnia pulicaria

mortality

LC50

hours

697

μg/L

12 ECHA Information on Registered Substances

Lind, D., K. Alto, and S. Chatterton.

Regional Copper-Nickel Study: Aquatic Toxicology Study.

Minnesota Environmental Quality Board

2021/03/02

甲殻類

Daphnia pulicaria

mortality

LC50

hours

1034

μg/L

12 ECHA Information on Registered Substances

Lind, D., K. Alto, and S. Chatterton.

Regional Copper-Nickel Study: Aquatic Toxicology Study.

Minnesota Environmental Quality Board

2021/03/02

甲殻類

Daphnia pulicaria

mortality

LC50

hours

1836

μg/L

12 ECHA Information on Registered Substances

Lind, D., K. Alto, and S. Chatterton.

Regional Copper-Nickel Study: Aquatic Toxicology Study.

Minnesota Environmental Quality Board

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

74.4

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

87.5

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

276

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

LC50

hours

1940

mg/L

12 ECHA Information on Registered Substances

government document

2021/03/02

甲殻類

Daphnia magna

LC50

hours

2360

mg/L

12 ECHA Information on Registered Substances

government document

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

82.1

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

LC50

hours

2340

mg/L

12 ECHA Information on Registered Substances

government document

2021/03/02

甲殻類

Daphnia magna

mobility

LC50

hours

7.36

mg/L

○

12 ECHA Information on Registered Substances

publication

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

140

μg/L

12 ECHA Information on Registered Substances

Schubauer-Berigan, M.K., J.R. Dierkes, P.D. Monson, and G.T. Ankley

pH-Dependent toxicity of Cd, Cu, Ni, Pb and Zn to Ceriodaphnia dubia, Pimephales Promelas, Hyalella azteca and Lumbriculus variegates

Environmental Toxicology and Chemistry. 12

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

>200

μg/L

12 ECHA Information on Registered Substances

Schubauer-Berigan, M.K., J.R. Dierkes, P.D. Monson, and G.T. Ankley

pH-Dependent toxicity of Cd, Cu, Ni, Pb and Zn to Ceriodaphnia dubia, Pimephales Promelas, Hyalella azteca and Lumbriculus variegates

Environmental Toxicology and Chemistry. 12

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

133.1

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

121.6

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia pulicaria

mortality

LC50

hours

3316

μg/L

12 ECHA Information on Registered Substances

Lind, D., K. Alto, and S. Chatterton.

Regional Copper-Nickel Study: Aquatic Toxicology Study.

Minnesota Environmental Quality Board

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

266.3

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia pulicaria

mortality

LC50

hours

2182

μg/L

12 ECHA Information on Registered Substances

Lind, D., K. Alto, and S. Chatterton.

Regional Copper-Nickel Study: Aquatic Toxicology Study.

Minnesota Environmental Quality Board

2021/03/02

甲殻類

Daphnia pulicaria

mortality

LC50

hours

1141

μg/L

12 ECHA Information on Registered Substances

Lind, D., K. Alto, and S. Chatterton.

Regional Copper-Nickel Study: Aquatic Toxicology Study.

Minnesota Environmental Quality Board

2021/03/02

甲殻類

Daphnia magna

LC50

hours

1920

mg/L

12 ECHA Information on Registered Substances

government document

2021/03/02

甲殻類

Daphnia pulex

mortality

LC50

hours

912.332

μg/L

12 ECHA Information on Registered Substances

Jindal, R. and A. Verma

Heavy Metal Toxicity to Daphnia pulex

Indian J. Environ. Health. 32(3)

2021/03/02

甲殻類

Daphnia magna

mortality

LC50

1068

μg/L

12 ECHA Information on Registered Substances

Pane, E.F., Smith, C., McGeer, J.C., and C.M. Wood.

Mechanisms of Acute and Chronic Waterborne Nickel Toxicity in the Freshwater Cladoceran, Daphnia magna

Environmental Science and Technology. 37

2021/03/02

甲殻類

Daphnia magna

LC50

hours

4970

mg/L

12 ECHA Information on Registered Substances

government document

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

202.3

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

214.1

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

Mortality

LD50

hours

mg/L

16 ECOTOX

Tomasik,P., C.H.D. Magadza, S. Mhizha, and A. Chirume

The Metal-Metal Interactions in Biological Systems. Part III. Daphnia magna

Water Air Soil Pollut.82

2020/11/12

甲殻類

Daphnia magna

Mortality

LD50

hours

mg/L

16 ECOTOX

Tomasik,P., C.H.D. Magadza, S. Mhizha, and A. Chirume

The Metal-Metal Interactions in Biological Systems. Part III. Daphnia magna

Water Air Soil Pollut.82

2020/11/12

甲殻類

Daphnia magna

Mortality

LC50

hours

915

μg/L

16 ECOTOX

Call,D.J., L.T. Brooke, N. Ahmad, and J.E. Richter

Toxicity and Metabolism Studies with EPA (Environmental Protection Agency) Priority Pollutants and Related Chemicals in Freshwater Organisms

EPA 600/3-83-095, U.S.EPA, Duluth, MN

2020/11/12

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

105.1

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC50

hours

107.3

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

mortality

LC50

mg/L

12 ECHA Information on Registered Substances

other company data

2021/03/02

甲殻類

Daphnia magna

EC50

hours

>100

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

LC50

hours

4960

mg/L

12 ECHA Information on Registered Substances

government document

2021/03/02

甲殻類

Daphnia magna

Mortality

LC50

hours

0.915

mgNi/L [measured]

8 NITE 化学物質の初期リスク評価書

Call, D.J., Brooke, L.T. Ahmad, N. and Richter, J.E.

Toxicity and metabolism studies with EPA priority pollutants and related chemicals in freshwater organisms.

EPA 600/3-83-095, U.S.EPA, Duluth, MN

2021/04/06

甲殻類

Daphnia pulicaria

mortality

LC50

hours

3156

μg/L

12 ECHA Information on Registered Substances

Lind, D., K. Alto, and S. Chatterton.

Regional Copper-Nickel Study: Aquatic Toxicology Study.

Minnesota Environmental Quality Board

2021/03/02

甲殻類

Daphnia pulicaria

mortality

LC50

hours

2042

μg/L

12 ECHA Information on Registered Substances

Lind, D., K. Alto, and S. Chatterton.

Regional Copper-Nickel Study: Aquatic Toxicology Study.

Minnesota Environmental Quality Board

2021/03/02

甲殻類

Daphnia pulicaria

mortality

LC50

hours

2717

μg/L

12 ECHA Information on Registered Substances

Lind, D., K. Alto, and S. Chatterton.

Regional Copper-Nickel Study: Aquatic Toxicology Study.

Minnesota Environmental Quality Board

2021/03/02

甲殻類

Daphnia magna

EC50

hours

100

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia pulicaria

mortality

LC50

hours

3607

μg/L

12 ECHA Information on Registered Substances

Lind, D., K. Alto, and S. Chatterton.

Regional Copper-Nickel Study: Aquatic Toxicology Study.

Minnesota Environmental Quality Board

2021/03/02

甲殻類

Daphnia magna

reproduction

EC50

days

118

μg/L

12 ECHA Information on Registered Substances

Nys C, Asselman J, Hochmuth JD, Janssen CR, Blust R, Smolders E, and De Schamphelaere KAC

Mixture toxicity of nickel and zinc to Daphnia magna is noninteractive at low effect sizes but becomes synergistic at high effect sizes

Environmental Toxicology and Chemistry; 34(5)

2021/03/02

甲殻類

Ceriodaphnia dubia

Survival

EC10

days

μg/L

12 ECHA Information on Registered Substances

Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R

Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters

Environmental Toxicology and Chemistry. 37 (10)

2021/03/02

甲殻類

Daphnia magna

mortality

LC10

days

250

μg/L

12 ECHA Information on Registered Substances

Pavlaki MD, Pereira R, Loureiro S, Soares AMVM

Effects of binary mixtures on the life traits of Daphnia magna

Ecotoxicology and Environmental Safety. 74

2021/03/02

甲殻類

Daphnia magna

reproduction

EC50

days

1035

nmol/L

12 ECHA Information on Registered Substances

Nys C, Asselman J, Hochmuth JD, Janssen CR, Blust R, Smolders E, and De Schamphelaere KAC

Mixture toxicity of nickel and zinc to Daphnia magna is noninteractive at low effect sizes but becomes synergistic at high effect sizes

Environmental Toxicology and Chemistry; 34(5)

2021/03/02

甲殻類

Daphnia magna

mortality

LC20

days

300

μg/L

12 ECHA Information on Registered Substances

Pavlaki MD, Pereira R, Loureiro S, Soares AMVM

Effects of binary mixtures on the life traits of Daphnia magna

Ecotoxicology and Environmental Safety. 74

2021/03/02

甲殻類

Daphnia magna

reproduction

EC50

days

μg/L

12 ECHA Information on Registered Substances

Biesinger, K.E. and G.M. Christensen

Effects of various metals on survival, growth, reproduction, and metabolism of Daphnia magna

Journal of Fisheries Research Board of Canada. 29(12)

2021/03/02

甲殻類

Daphnia magna

mortality

LC50

days

130

μg/L

12 ECHA Information on Registered Substances

Biesinger, K.E. and G.M. Christensen

Effects of various metals on survival, growth, reproduction, and metabolism of Daphnia magna

Journal of Fisheries Research Board of Canada. 29(12)

2021/03/02

甲殻類

Daphnia magna

Reproduction and growth of Fo generation

LOEC

days

μg/L

12 ECHA Information on Registered Substances

Pane, E.F., McGeer, J.C., and C.M. Wood.

Effects of Chronic Waterborne Nickel Exposure on Two Successive Generations of Daphnia magna.

Environ. Toxicol. Chem. 23

2021/03/02

甲殻類

Ceriodaphnia dubia

survival

LOEC

days

μg/L

12 ECHA Information on Registered Substances

Kszos, L.A., A.J. Stewart, and P.A. Taylor

An evaluation of nickel toxicity to Ceriodaphnia dubia and Daphnia magna in a contaminated stream and in laboratory tests

Environmental Toxicology and Chemistry. 11

2021/03/02

甲殻類

Ceriodaphnia dubia

survival

LOEC

days

7.5

μg/L

12 ECHA Information on Registered Substances

Kszos, L.A., A.J. Stewart, and P.A. Taylor

An evaluation of nickel toxicity to Ceriodaphnia dubia and Daphnia magna in a contaminated stream and in laboratory tests

Environmental Toxicology and Chemistry. 11

2021/03/02

甲殻類

Ceriodaphnia dubia

survival and reproduction

NOEC

days

7.5

μg/L

12 ECHA Information on Registered Substances

Kszos, L.A., A.J. Stewart, and P.A. Taylor

An evaluation of nickel toxicity to Ceriodaphnia dubia and Daphnia magna in a contaminated stream and in laboratory tests

Environmental Toxicology and Chemistry. 11

2021/03/02

甲殻類

Daphnia magna

reproduction

EC16

days

μg/L

12 ECHA Information on Registered Substances

Biesinger, K.E. and G.M. Christensen

Effects of various metals on survival, growth, reproduction, and metabolism of Daphnia magna

Journal of Fisheries Research Board of Canada. 29(12)

2021/03/02

甲殻類

Daphnia magna

reproduction

EC10

days

800

nmol/L

12 ECHA Information on Registered Substances

Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.

The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.

Environ Toxicol Chem. 2016 May;35(5)

2021/03/02

甲殻類

Daphnia magna

mortality

LC50

days

71.9

μg/L

12 ECHA Information on Registered Substances

Pane, E.F., McGeer, J.C., and C.M. Wood.

Effects of Chronic Waterborne Nickel Exposure on Two Successive Generations of Daphnia magna.

Environ. Toxicol. Chem. 23

2021/03/02

甲殻類

Daphnia magna

reproduction

EC50

days

412

nmol/L

12 ECHA Information on Registered Substances

Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.

The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.

Environ Toxicol Chem. 2016 May;35(5)

2021/03/02

甲殻類

Daphnia magna

reproduction

EC50

days

584

nmol/L

12 ECHA Information on Registered Substances

Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.

The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.

Environ Toxicol Chem. 2016 May;35(5)

2021/03/02

甲殻類

Daphnia magna

reproduction

EC20

days

1398

nmol/L

12 ECHA Information on Registered Substances

Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.

The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.

Environ Toxicol Chem. 2016 May;35(5)

2021/03/02

甲殻類

Daphnia magna

reproduction

EC20

days

469

nmol/L

12 ECHA Information on Registered Substances

Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.

The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.

Environ Toxicol Chem. 2016 May;35(5)

2021/03/02

甲殻類

Daphnia magna

reproduction

EC50

days

3606

nmol/L

12 ECHA Information on Registered Substances

Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.

The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.

Environ Toxicol Chem. 2016 May;35(5)

2021/03/02

甲殻類

Daphnia magna

Reproduction and growth of Fo generation

NOEC

days

μg/L

12 ECHA Information on Registered Substances

Pane, E.F., McGeer, J.C., and C.M. Wood.

Effects of Chronic Waterborne Nickel Exposure on Two Successive Generations of Daphnia magna.

Environ. Toxicol. Chem. 23

2021/03/02

甲殻類

Daphnia magna

reproduction

EC50

days

492

μg/L

12 ECHA Information on Registered Substances

Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.

The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.

Environ Toxicol Chem. 2016 May;35(5)

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

LOEC

days

34.9

μgNi/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

NOEC

days

21.5

μgNi/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

LOEC

days

33.4

μgNi/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

EC20

days

4.7

μg/L

12 ECHA Information on Registered Substances

Keithly, J., J.A. Brooker, D.K. DeForest, B.K. Wu, and K.V. Brix

Acute and chronic toxicity of nickel to a cladoceran (Ceriodaphnia dubia) and an amphipod (Hyallela azteca)

Environmental Toxicology and Chemistry, Vol. 23, No.3

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

EC20

days

μg/L

12 ECHA Information on Registered Substances

Keithly, J., J.A. Brooker, D.K. DeForest, B.K. Wu, and K.V. Brix

Acute and chronic toxicity of nickel to a cladoceran (Ceriodaphnia dubia) and an amphipod (Hyallela azteca)

Environmental Toxicology and Chemistry, Vol. 23, No.3

2021/03/02

甲殻類

Daphnia magna

for 105 mg/L hardness test

ChV

days

129

μg/L

12 ECHA Information on Registered Substances

government document

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

EC20

days

6.9

μg/L

12 ECHA Information on Registered Substances

Keithly, J., J.A. Brooker, D.K. DeForest, B.K. Wu, and K.V. Brix

Acute and chronic toxicity of nickel to a cladoceran (Ceriodaphnia dubia) and an amphipod (Hyallela azteca)

Environmental Toxicology and Chemistry, Vol. 23, No.3

2021/03/02

甲殻類

Daphnia magna

reproduction

LOEC

weeks

160

μg/L

12 ECHA Information on Registered Substances

Munzinger, A

The influence of Nickel on population dynamics and on some demographic parameters of Daphnia magna

Hydrobiologia. 277

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

EC10

days

>2.8～<53.6

μg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

reproduction

EC20

days

107

μg/L

12 ECHA Information on Registered Substances

Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.

The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.

Environ Toxicol Chem. 2016 May;35(5)

2021/03/02

甲殻類

Daphnia magna

reproduction

EC20

days

191

μg/L

12 ECHA Information on Registered Substances

Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.

The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.

Environ Toxicol Chem. 2016 May;35(5)

2021/03/02

甲殻類

Daphnia magna

body length of primiparous individuals (in

LOEC

days

μg/L

12 ECHA Information on Registered Substances

Munzinger, A

Effects of nickel on Daphnia magna during chronic exposure and alterations in the toxicity to generations pre-exposed to nickel

Wat. Res. 24(7)

2021/03/02

甲殻類

Daphnia magna

body length of primiparous individuals (in

NOEC

days

μg/L

12 ECHA Information on Registered Substances

Munzinger, A

Effects of nickel on Daphnia magna during chronic exposure and alterations in the toxicity to generations pre-exposed to nickel

Wat. Res. 24(7)

2021/03/02

甲殻類

Daphnia magna

reproduction

LOEC

days

μg/L

12 ECHA Information on Registered Substances

Munzinger, A

Effects of nickel on Daphnia magna during chronic exposure and alterations in the toxicity to generations pre-exposed to nickel

Wat. Res. 24(7)

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

EC20

days

μg/L

12 ECHA Information on Registered Substances

Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC

Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata

Environmental Toxicology and Chemistry. 36 (4)

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

EC10

days

μg/L

12 ECHA Information on Registered Substances

Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC

Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata

Environmental Toxicology and Chemistry. 36 (4)

2021/03/02

甲殻類

Daphnia magna

51 mg/L hardness test

EC50

days

14.8

μg/L

12 ECHA Information on Registered Substances

government document

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

NOEC

days

38.6

μgNi/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

reproduction

LOEC

days

>=6.13～<=93.8

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

reproduction

EC10

days

>=8.78～<=76.7

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

reproduction

EC20

days

>=12.7～<=84.3

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC20

days

4.8

μg/L

12 ECHA Information on Registered Substances

Keithly, J., J.A. Brooker, D.K. DeForest, B.K. Wu, and K.V. Brix

Acute and chronic toxicity of nickel to a cladoceran (Ceriodaphnia dubia) and an amphipod (Hyallela azteca)

Environmental Toxicology and Chemistry, Vol. 23, No.3

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC20

days

11.9

μg/L

12 ECHA Information on Registered Substances

Keithly, J., J.A. Brooker, D.K. DeForest, B.K. Wu, and K.V. Brix

Acute and chronic toxicity of nickel to a cladoceran (Ceriodaphnia dubia) and an amphipod (Hyallela azteca)

Environmental Toxicology and Chemistry, Vol. 23, No.3

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC20

days

10.4

μg/L

12 ECHA Information on Registered Substances

Keithly, J., J.A. Brooker, D.K. DeForest, B.K. Wu, and K.V. Brix

Acute and chronic toxicity of nickel to a cladoceran (Ceriodaphnia dubia) and an amphipod (Hyallela azteca)

Environmental Toxicology and Chemistry, Vol. 23, No.3

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

NOEC

days

5.3～15.3

μg/L

12 ECHA Information on Registered Substances

Keithly, J., J.A. Brooker, D.K. DeForest, B.K. Wu, and K.V. Brix

Acute and chronic toxicity of nickel to a cladoceran (Ceriodaphnia dubia) and an amphipod (Hyallela azteca)

Environmental Toxicology and Chemistry, Vol. 23, No.3

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

EC20

days

<3.8

μg/L

12 ECHA Information on Registered Substances

Keithly, J., J.A. Brooker, D.K. DeForest, B.K. Wu, and K.V. Brix

Acute and chronic toxicity of nickel to a cladoceran (Ceriodaphnia dubia) and an amphipod (Hyallela azteca)

Environmental Toxicology and Chemistry, Vol. 23, No.3

2021/03/02

甲殻類

Daphnia magna

growth

NOEC

days

μg/L

12 ECHA Information on Registered Substances

Pane, E.F., McGeer, J.C., and C.M. Wood.

Effects of Chronic Waterborne Nickel Exposure on Two Successive Generations of Daphnia magna.

Environ. Toxicol. Chem. 23

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

LC20

days

<3.8

μg/L

12 ECHA Information on Registered Substances

Keithly, J., J.A. Brooker, D.K. DeForest, B.K. Wu, and K.V. Brix

Acute and chronic toxicity of nickel to a cladoceran (Ceriodaphnia dubia) and an amphipod (Hyallela azteca)

Environmental Toxicology and Chemistry, Vol. 23, No.3

2021/03/02

甲殻類

Daphnia magna

reproduction

EC50

days

134

μg/L

12 ECHA Information on Registered Substances

Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.

The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.

Environ Toxicol Chem. 2016 May;35(5)

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

LOEC

days

62.4

μgNi/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

NOEC

days

20.2

μgNi/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

mortality

LOEC

days

>37.4～<=257

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

mortality

LC50

days

>37.4～<=144

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

reproduction

EC50

days

>=23.6～<=108

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

reproduction

NOEC

days

6.13～<=48.5

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

reproduction

% reduction in reproduction

days

0.4

mg/L

12 ECHA Information on Registered Substances

Bozich J, Hang M, Hamers R, Klaper R

Core chemistry influences the toxicity of multicomponent metal oxide nanomaterials, lithium nickel manganese cobalt oxide, and lithium cobalt oxide to Daphnia magna

Environ Toxicol Chem; 36(9)

2021/03/02

甲殻類

Daphnia magna

survival and reproduction

NOEC

days

μg/L

12 ECHA Information on Registered Substances

Kuhn, R., M. Pattard, K-D. Pernak, and A. Winter

Results of the harmful effects of water pollutants to Daphnia magna in the 21 day reproduction test

Water Res. 23(4)

2021/03/02

甲殻類

Daphnia magna

mortality

NOEC

days

>=37～<=150

μg/L

○

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Ceriodaphnia dubia

Mortality

NR-LETH

days

7.5

μg/L

16 ECOTOX

Kszos,L.A., A.J. Stewart, and P.A. Taylor

An Evaluation of Nickel Toxicity to Ceriodaphnia dubia and Daphnia magna in a Contaminated Stream and in Laboratory Tests

Environ. Toxicol. Chem.11(7)

2020/11/12

甲殻類

Daphnia magna

reproduction

EC10

days

μg/L

12 ECHA Information on Registered Substances

Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.

The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.

Environ Toxicol Chem. 2016 May;35(5)

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

NOEC

days

<8.3

μgNi/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Chironomus riparius

Growth

MATC

days

1100

μg/L

16 ECOTOX

Powlesland,C., and J. George

Acute and Chronic Toxicity of Nickel to Larvae of Chironomus riparis (Meigen)

Environ. Pollut. A.42(1)

2020/11/12

甲殻類

Daphnia magna

mortality

% mortality

days

0.4

mg/L

12 ECHA Information on Registered Substances

Bozich J, Hang M, Hamers R, Klaper R

Core chemistry influences the toxicity of multicomponent metal oxide nanomaterials, lithium nickel manganese cobalt oxide, and lithium cobalt oxide to Daphnia magna

Environ Toxicol Chem; 36(9)

2021/03/02

甲殻類

Daphnia magna

reproduction

NOEC

days

μg/L

12 ECHA Information on Registered Substances

Munzinger, A

Effects of nickel on Daphnia magna during chronic exposure and alterations in the toxicity to generations pre-exposed to nickel

Wat. Res. 24(7)

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

EC50

days

ca.43～ca.52

μg/L

12 ECHA Information on Registered Substances

Nys C, Janssen CR, Blust R, Smolders E, de Schamphelaere KAC

Reproductive toxicity of binary and ternary mixture combinations of nickel, zinc, and lead to Ceriodaphnia dubia is best predicted with the independent action model

Environmental Toxicology & Chemistry; 35(7)

2021/03/02

甲殻類

Ceriodaphnia dubia

mortality

EC50

days

ca.478～ca.546

nmol/L

12 ECHA Information on Registered Substances

Nys C, Janssen CR, Blust R, Smolders E, de Schamphelaere KAC

Reproductive toxicity of binary and ternary mixture combinations of nickel, zinc, and lead to Ceriodaphnia dubia is best predicted with the independent action model

Environmental Toxicology & Chemistry; 35(7)

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

NOEC

days

<3.7

μgNi/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

reproduction

EC50

days

1652

nmol/L

12 ECHA Information on Registered Substances

Nys C, Asselman J, Hochmuth JD, Janssen CR, Blust R, Smolders E, and De Schamphelaere KAC

Mixture toxicity of nickel and zinc to Daphnia magna is noninteractive at low effect sizes but becomes synergistic at high effect sizes

Environmental Toxicology and Chemistry; 34(5)

2021/03/02

甲殻類

Daphnia magna

reproduction

EC10

days

109

μg/L

12 ECHA Information on Registered Substances

Nys C, Janssen CR, Van Sprang P, De Schamphelaere KA.

The effect of pH on chronic aquatic nickel toxicity is dependent on the pH itself: Extending the chronic nickel bioavailability models.

Environ Toxicol Chem. 2016 May;35(5)

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

NOEC

days

<12.2

μgNi/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

growth

NOEC

weeks

μg/L

12 ECHA Information on Registered Substances

Munzinger, A

The influence of Nickel on population dynamics and on some demographic parameters of Daphnia magna

Hydrobiologia. 277

2021/03/02

甲殻類

Daphnia magna

mortality, growth and reproduction

LOEC

days

0.32

mg/L

12 ECHA Information on Registered Substances

Enserink, E.L., J.L. Maas-Diepeveen, and C.J. Van Leeuwen

Combined effects of metals; an ecotoxicological evaluation

Wat. Res. 25(6)

2021/03/02

甲殻類

Daphnia magna

reproduction

EC50

days

289.29

μg/L

12 ECHA Information on Registered Substances

Pavlaki MD, Pereira R, Loureiro S, Soares AMVM

Effects of binary mixtures on the life traits of Daphnia magna

Ecotoxicology and Environmental Safety. 74

2021/03/02

甲殻類

Daphnia magna

mortality

LC100

days

350

μg/L

12 ECHA Information on Registered Substances

Pavlaki MD, Pereira R, Loureiro S, Soares AMVM

Effects of binary mixtures on the life traits of Daphnia magna

Ecotoxicology and Environmental Safety. 74

2021/03/02

甲殻類

Daphnia magna

mortality, growth and reproduction

NOEC

days

0.2

mg/L

12 ECHA Information on Registered Substances

Enserink, E.L., J.L. Maas-Diepeveen, and C.J. Van Leeuwen

Combined effects of metals; an ecotoxicological evaluation

Wat. Res. 25(6)

2021/03/02

甲殻類

Daphnia magna

mortality, growth and reproduction

LC50

days

0.36

mg/L

12 ECHA Information on Registered Substances

Enserink, E.L., J.L. Maas-Diepeveen, and C.J. Van Leeuwen

Combined effects of metals; an ecotoxicological evaluation

Wat. Res. 25(6)

2021/03/02

甲殻類

Daphnia magna

for 205 mg/L hardness test

ChV

days

357

μg/L

12 ECHA Information on Registered Substances

government document

2021/03/02

甲殻類

Daphnia magna

growth

LOEC

weeks

μg/L

12 ECHA Information on Registered Substances

Munzinger, A

The influence of Nickel on population dynamics and on some demographic parameters of Daphnia magna

Hydrobiologia. 277

2021/03/02

甲殻類

Daphnia magna

growth

LOEC

days

μg/L

12 ECHA Information on Registered Substances

Pane, E.F., McGeer, J.C., and C.M. Wood.

Effects of Chronic Waterborne Nickel Exposure on Two Successive Generations of Daphnia magna.

Environ. Toxicol. Chem. 23

2021/03/02

甲殻類

Daphnia magna

reproduction

NOEC

days

140

μg/L

12 ECHA Information on Registered Substances

Perez E, Hoang TC

Responses of Daphnia magna to chronic exposure of cadium and nickel mixtures

Chemosphere. 208

2021/03/02

甲殻類

Daphnia magna

reproduction

NOEC

days

>=160

μg/L

12 ECHA Information on Registered Substances

Perez E, Hoang TC

Responses of Daphnia magna to chronic exposure of cadium and nickel mixtures

Chemosphere. 208

2021/03/02

甲殻類

Daphnia magna

reproduction

NOEC

weeks

120

μg/L

12 ECHA Information on Registered Substances

Munzinger, A

The influence of Nickel on population dynamics and on some demographic parameters of Daphnia magna

Hydrobiologia. 277

2021/03/02

甲殻類

Daphnia magna

reproduction

EC50

17.3

μg/L

12 ECHA Information on Registered Substances

Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC

Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation

Environmental Toxicology and Chemistry 37

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

EC10

days

nmol/L

12 ECHA Information on Registered Substances

Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC

Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata

Environmental Toxicology and Chemistry. 36 (4)

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

EC20

days

120

nmol/L

12 ECHA Information on Registered Substances

Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC

Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata

Environmental Toxicology and Chemistry. 36 (4)

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

EC50

days

240

nmol/L

12 ECHA Information on Registered Substances

Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC

Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata

Environmental Toxicology and Chemistry. 36 (4)

2021/03/02

甲殻類

Daphnia magna

reproduction

EC50

82.1

μg/L

12 ECHA Information on Registered Substances

Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC

Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation

Environmental Toxicology and Chemistry 37

2021/03/02

甲殻類

Daphnia magna

reproduction

EC20

μg/L

12 ECHA Information on Registered Substances

Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC

Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation

Environmental Toxicology and Chemistry 37

2021/03/02

甲殻類

Daphnia magna

reproduction

EC50

12.9

μg/L

12 ECHA Information on Registered Substances

Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC

Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation

Environmental Toxicology and Chemistry 37

2021/03/02

甲殻類

Ceriodaphnia dubia

Survival

EC50

days

20.1

μg/L

12 ECHA Information on Registered Substances

Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R

Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters

Environmental Toxicology and Chemistry. 37 (10)

2021/03/02

甲殻類

Daphnia magna

reproduction

EC50

129.1

μg/L

12 ECHA Information on Registered Substances

Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC

Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation

Environmental Toxicology and Chemistry 37

2021/03/02

甲殻類

Ceriodaphnia dubia

Survival

EC10

days

6.2

μg/L

12 ECHA Information on Registered Substances

Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R

Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters

Environmental Toxicology and Chemistry. 37 (10)

2021/03/02

甲殻類

Daphnia magna

reproduction

EC20

105.2

μg/L

12 ECHA Information on Registered Substances

Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC

Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation

Environmental Toxicology and Chemistry 37

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

EC50

days

400

nmol/L

12 ECHA Information on Registered Substances

Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC

Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata

Environmental Toxicology and Chemistry. 36 (4)

2021/03/02

甲殻類

Daphnia magna

reproduction

EC50

75.1

μg/L

12 ECHA Information on Registered Substances

Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC

Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation

Environmental Toxicology and Chemistry 37

2021/03/02

甲殻類

Daphnia magna

reproduction

EC10

24.4

μg/L

12 ECHA Information on Registered Substances

Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC

Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation

Environmental Toxicology and Chemistry 37

2021/03/02

甲殻類

Ceriodaphnia dubia

Survival

EC50

days

11.8

μg/L

12 ECHA Information on Registered Substances

Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R

Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters

Environmental Toxicology and Chemistry. 37 (10)

2021/03/02

甲殻類

Daphnia magna

reproduction

NOEC

days

μg/L

12 ECHA Information on Registered Substances

Perez E, Hoang TC

Responses of Daphnia magna to chronic exposure of cadium and nickel mixtures

Chemosphere. 208

2021/03/02

甲殻類

Daphnia magna

growth

NOEC

days

μg/L

12 ECHA Information on Registered Substances

Perez E, Hoang TC

Responses of Daphnia magna to chronic exposure of cadium and nickel mixtures

Chemosphere. 208

2021/03/02

甲殻類

Daphnia magna

mortality

NOEC

days

μg/L

12 ECHA Information on Registered Substances

Perez E, Hoang TC

Responses of Daphnia magna to chronic exposure of cadium and nickel mixtures

Chemosphere. 208

2021/03/02

甲殻類

Daphnia magna

reproduction

EC20

113.1

μg/L

12 ECHA Information on Registered Substances

Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC

Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation

Environmental Toxicology and Chemistry 37

2021/03/02

甲殻類

Daphnia magna

reproduction

EC50

143.2

μg/L

12 ECHA Information on Registered Substances

Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC

Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation

Environmental Toxicology and Chemistry 37

2021/03/02

甲殻類

Ceriodaphnia dubia

Survival

EC50

days

6.7

μg/L

12 ECHA Information on Registered Substances

Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R

Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters

Environmental Toxicology and Chemistry. 37 (10)

2021/03/02

甲殻類

Ceriodaphnia dubia

Survival

EC50

days

4.4

μg/L

12 ECHA Information on Registered Substances

Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R

Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters

Environmental Toxicology and Chemistry. 37 (10)

2021/03/02

甲殻類

Ceriodaphnia dubia

survival and reproduction

NOEC

days

3.8

μg/L

12 ECHA Information on Registered Substances

Kszos, L.A., A.J. Stewart, and P.A. Taylor

An evaluation of nickel toxicity to Ceriodaphnia dubia and Daphnia magna in a contaminated stream and in laboratory tests

Environmental Toxicology and Chemistry. 11

2021/03/02

甲殻類

Daphnia magna

reproduction

EC50

days

165

μg/L

12 ECHA Information on Registered Substances

Nys C, Asselman J, Hochmuth JD, Janssen CR, Blust R, Smolders E, and De Schamphelaere KAC

Mixture toxicity of nickel and zinc to Daphnia magna is noninteractive at low effect sizes but becomes synergistic at high effect sizes

Environmental Toxicology and Chemistry; 34(5)

2021/03/02

甲殻類

Daphnia magna

reproduction

EC10

93.3

μg/L

12 ECHA Information on Registered Substances

Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC

Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation

Environmental Toxicology and Chemistry 37

2021/03/02

甲殻類

Daphnia magna

reproduction

EC10

98.5

μg/L

12 ECHA Information on Registered Substances

Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC

Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation

Environmental Toxicology and Chemistry 37

2021/03/02

甲殻類

Daphnia magna

reproduction

EC10

18.8

μg/L

12 ECHA Information on Registered Substances

Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC

Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation

Environmental Toxicology and Chemistry 37

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

EC20

days

303

nmol/L

12 ECHA Information on Registered Substances

Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC

Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata

Environmental Toxicology and Chemistry. 36 (4)

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

EC10

days

258

nmol/L

12 ECHA Information on Registered Substances

Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC

Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata

Environmental Toxicology and Chemistry. 36 (4)

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

EC50

days

μg/L

12 ECHA Information on Registered Substances

Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC

Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata

Environmental Toxicology and Chemistry. 36 (4)

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

EC20

days

μg/L

12 ECHA Information on Registered Substances

Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC

Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata

Environmental Toxicology and Chemistry. 36 (4)

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

EC10

days

μg/L

12 ECHA Information on Registered Substances

Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC

Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata

Environmental Toxicology and Chemistry. 36 (4)

2021/03/02

甲殻類

Ceriodaphnia dubia

Survival

EC10

days

4.9

μg/L

12 ECHA Information on Registered Substances

Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R

Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters

Environmental Toxicology and Chemistry. 37 (10)

2021/03/02

甲殻類

Daphnia magna

reproduction

LOEC

days

μg/L

12 ECHA Information on Registered Substances

Perez E, Hoang TC

Responses of Daphnia magna to chronic exposure of cadium and nickel mixtures

Chemosphere. 208

2021/03/02

甲殻類

Ceriodaphnia dubia

reproduction

EC50

days

μg/L

12 ECHA Information on Registered Substances

Nys C, van Regenmortal T, Janssen CR, Blust R, Smolders E, De Schamphelaere KAC

Comparison of chronic mixture toxicity of Nickel-Zinc-Copper and Nickel-Zinc-Copper-Cadmium mixtures between Ceriodaphnia Dubia and Pseudokirchneriella subcapitata

Environmental Toxicology and Chemistry. 36 (4)

2021/03/02

甲殻類

Daphnia magna

mortality

LOEC

days

μg/L

12 ECHA Information on Registered Substances

Perez E, Hoang TC

Responses of Daphnia magna to chronic exposure of cadium and nickel mixtures

Chemosphere. 208

2021/03/02

甲殻類

Ceriodaphnia dubia

Survival

EC10

days

3.6

μg/L

12 ECHA Information on Registered Substances

Peters A, Merrington G, Schlekat C, De Schamphelaere K, Stauber J, Batley G, Harford A, van Dam R, Pease C, Mooney T, Warne M, Hickey C, Glazebrook P, Chapman J, Smith R, Krassoi R

Validation of the Nickel Biotic Ligand Model for Locally Relevant Species in Australian Freshwaters

Environmental Toxicology and Chemistry. 37 (10)

2021/03/02

甲殻類

Daphnia magna

growth

LOEC

days

μg/L

12 ECHA Information on Registered Substances

Perez E, Hoang TC

Responses of Daphnia magna to chronic exposure of cadium and nickel mixtures

Chemosphere. 208

2021/03/02

甲殻類

Daphnia magna

reproduction

EC20

32.6

μg/L

12 ECHA Information on Registered Substances

Pereira CMS, Everaert G, Blust R, De Schamphelaere KAC

Multigenerational effects of nickel on Daphnia magna depend on temperature and the magnitude of the effect in the first generation

Environmental Toxicology and Chemistry 37

2021/03/02

魚類

Gasterosteus aculeatus (Three-spined stickleback)

Mortality

NR-LETH

days

800

μg/L

16 ECOTOX

Jones,J.R.E.

The Relation Between the Electrolytic Solution Pressures of the Metals and Their Toxicity to the Stickleback (Gasterosteus aculeatus L.)

J. Exp. Biol.16(4)

2020/11/12

魚類

Oncorhynchus mykiss (Rainbow trout)

Mortality

LC50

days

35500

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Hale,J.G.

Toxicity of Metal Mining Wastes

Bull. Environ. Contam. Toxicol.17(1): 66-73

1977

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Mortality

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Reproduction

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Reproduction

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Biochemical

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Growth

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2016/03/25

魚類

Gasterosteus aculeatus (Three-spined stickleback)

Mortality

days

800

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Jones,J.R.E.

The Relation Between the Electrolytic Solution Pressures of the Metals and Their Toxicity to the Stickleback (Gasterosteus aculeatus L.)

J. Exp. Biol.16(4): 425-437

1939

2016/03/25

魚類

Cyprinus carpio (Carp)

Mortality

LC50

days

29100

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Rehwoldt,R., G. Bida, and B. Nerrie

Acute Toxicity of Copper, Nickel, and Zinc Ions to Some Hudson River Fish Species

Bull. Environ. Contam. Toxicol.6(5): 445-448

1971

2016/03/25

魚類

Cyprinus carpio (Carp)

Mortality

LC50

days

10600

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Rehwoldt,R., G. Bida, and B. Nerrie

Acute Toxicity of Copper, Nickel, and Zinc Ions to Some Hudson River Fish Species

Bull. Environ. Contam. Toxicol.6(5): 445-448

1971

2016/03/25

魚類

Cyprinus carpio (Carp)

Mortality

LC50

days

38200

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Rehwoldt,R., G. Bida, and B. Nerrie

Acute Toxicity of Copper, Nickel, and Zinc Ions to Some Hudson River Fish Species

Bull. Environ. Contam. Toxicol.6(5): 445-448

1971

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Reproduction

LOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Growth

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Biochemical

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Accumulation

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Biochemical

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Accumulation

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Growth

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Biochemical

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Growth

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Growth

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Growth

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Accumulation

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Accumulation

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Growth

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Growth

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2017/03/15

魚類

Pimephales promelas (Fathead minnow)

Growth

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2017/03/15

魚類

Pimephales promelas (Fathead minnow)

Accumulation

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2017/03/15

魚類

Pimephales promelas (Fathead minnow)

Accumulation

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2017/03/15

魚類

Pimephales promelas (Fathead minnow)

Accumulation

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2017/03/15

魚類

Pimephales promelas (Fathead minnow)

Growth

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2017/03/15

魚類

Pimephales promelas (Fathead minnow)

Reproduction

LOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2017/03/15

魚類

Oncorhynchus mykiss (Rainbow trout)

Mortality

LC50

days

35500

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Hale,J.G.

Toxicity of Metal Mining Wastes

Bull. Environ. Contam. Toxicol.17(1): 66-73

1977

2017/03/15

魚類

Pimephales promelas (Fathead minnow)

Growth

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2017/03/15

魚類

Gasterosteus aculeatus (Three-spined stickleback)

Mortality

days

800

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Jones,J.R.E.

The Relation Between the Electrolytic Solution Pressures of the Metals and Their Toxicity to the Stickleback (Gasterosteus aculeatus L.)

J. Exp. Biol.16(4): 425-437

1939

2017/03/15

魚類

Pimephales promelas (Fathead minnow)

Growth

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2017/03/15

魚類

Pimephales promelas (Fathead minnow)

Growth

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2017/03/15

魚類

Pimephales promelas (Fathead minnow)

Biochemical

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2017/03/15

魚類

Pimephales promelas (Fathead minnow)

Reproduction

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2017/03/15

魚類

Pimephales promelas (Fathead minnow)

Mortality

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2017/03/15

魚類

Pimephales promelas (Fathead minnow)

Biochemical

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2017/03/15

魚類

Cyprinus carpio (Carp)

Mortality

LC50

days

38200

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Rehwoldt,R., G. Bida, and B. Nerrie

Acute Toxicity of Copper, Nickel, and Zinc Ions to Some Hudson River Fish Species

Bull. Environ. Contam. Toxicol.6(5): 445-448

1971

2017/03/15

魚類

Cyprinus carpio (Carp)

Mortality

LC50

days

29100

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Rehwoldt,R., G. Bida, and B. Nerrie

Acute Toxicity of Copper, Nickel, and Zinc Ions to Some Hudson River Fish Species

Bull. Environ. Contam. Toxicol.6(5): 445-448

1971

2017/03/15

魚類

Cyprinus carpio (Carp)

Mortality

LC50

days

10600

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Rehwoldt,R., G. Bida, and B. Nerrie

Acute Toxicity of Copper, Nickel, and Zinc Ions to Some Hudson River Fish Species

Bull. Environ. Contam. Toxicol.6(5): 445-448

1971

2017/03/15

魚類

Pimephales promelas (Fathead minnow)

Reproduction

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2017/03/15

魚類

Pimephales promelas (Fathead minnow)

Growth

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2017/03/15

魚類

Pimephales promelas (Fathead minnow)

Biochemical

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2017/03/15

魚類

Pimephales promelas (Fathead minnow)

Accumulation

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2017/03/15

魚類

Pimephales promelas (Fathead minnow)

Biochemical

NOEC

days

91.33

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Ouellette,J.D., M.G. Dube, and S. Niyogi

A Single Metal, Metal Mixture, and Whole-Effluent Approach to Investigate Causes of Metal Mine Effluent Effects on Fathead Minnows (Pimephales promelas)

Water Air Soil Pollut.224(1462): 44 p.

2013

2017/03/15

魚類

Poecilia reticulata (Guppy)

mortality

LC50

hours

29.66

mg/L

12 ECHA Information on Registered Substances

Shuhaimi-Othman M, Yakub N, Ramle N-A, and Abas A.

Comparative toxicity of eight metals on freshwater fish.

Toxicology and Industrial Health; DOI

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

5.18

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H. and C. Henderson

The acute toxicity of some heavy metals to different species of warmwater fishes

Air Wat. Pollut. Int. J. 10

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H.

Chronic toxicity of nickel to the fathead minnow

J. Water Pollut. Control Fed. 46(4)

2021/03/02

魚類

Poecilia reticulata (Guppy)

mortality

LC50

hours

204.2

mg/L

12 ECHA Information on Registered Substances

Khunyakari, R.P., V. Tare, and R.N. Sharma.

Effects of some trace heavy metals on Poecilia reticulata (Peters).

Journal of Environmental Biology. 22(2)

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

hours

8.46

mgNi/L

12 ECHA Information on Registered Substances

Blaylock, B.G. and M.L. Frank.

A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).

Bull. Environ. Contam. Toxicol. 21(4/5)

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

hours

6.16

mgNi/L

12 ECHA Information on Registered Substances

Blaylock, B.G. and M.L. Frank.

A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).

Bull. Environ. Contam. Toxicol. 21(4/5)

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

257

hours

0.75

mgNi/L

12 ECHA Information on Registered Substances

Blaylock, B.G. and M.L. Frank.

A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).

Bull. Environ. Contam. Toxicol. 21(4/5)

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

2916～17678

μg/L

12 ECHA Information on Registered Substances

Lind, D., K. Alto, and S. Chatterton.

Regional Copper-Nickel Study: Aquatic Toxicology Study.

Minnesota Environmental Quality Board

2021/03/02

魚類

Poecilia reticulata (Guppy)

mortality

LC50

hours

336

mg/L

12 ECHA Information on Registered Substances

Khunyakari, R.P., V. Tare, and R.N. Sharma.

Effects of some trace heavy metals on Poecilia reticulata (Peters).

Journal of Environmental Biology. 22(2)

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

TLm

hours

10.4～10.6

mg/L

12 ECHA Information on Registered Substances

Rehwoldt, R., G. Bida, and B. Nerrie.

Acute toxicity of copper, nickel and zinc ions to some Hudson River fish species.

Bull. Environ. Contam. Toxicol. 6(5)

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

4.58

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H. and C. Henderson

The acute toxicity of some heavy metals to different species of warmwater fishes

Air Wat. Pollut. Int. J. 10

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

hours

6.1

mgNi/L

12 ECHA Information on Registered Substances

Blaylock, B.G. and M.L. Frank.

A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).

Bull. Environ. Contam. Toxicol. 21(4/5)

2021/03/02

魚類

Pimephales promelas

enzyme activities

NOEC

days

>=0.38

μmol nickel/g tissue

12 ECHA Information on Registered Substances

publication

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H.

Chronic toxicity of nickel to the fathead minnow

J. Water Pollut. Control Fed. 46(4)

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H.

Chronic toxicity of nickel to the fathead minnow

J. Water Pollut. Control Fed. 46(4)

2021/03/02

魚類

Lepomis macrochirus

mortality

LC50

hours

21.2

mg/L

12 ECHA Information on Registered Substances

Cairns, J., K.W. Thompson, and A.C. Hendricks

Effects of Fluctuating, Sublethal Applications of Heavy Metal Solutions Upon the Gill Ventilation Response of Bluegills (Lepomis macrochirus)

PB81-150997 or EPA-600/3-81-003

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

1.12

mg/L

12 ECHA Information on Registered Substances

Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl

The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas)

Water, Air, and Soil Pollution. 133

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

>4000

μg/L

12 ECHA Information on Registered Substances

Schubauer-Berigan, M.K., J.R. Dierkes, P.D. Monson, and G.T. Ankley

pH-Dependent toxicity of Cd, Cu, Ni, Pb and Zn to Ceriodaphnia dubia, Pimephales Promelas, Hyalella azteca and Lumbriculus variegates

Environmental Toxicology and Chemistry. 12

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

3400

μg/L

12 ECHA Information on Registered Substances

Schubauer-Berigan, M.K., J.R. Dierkes, P.D. Monson, and G.T. Ankley

pH-Dependent toxicity of Cd, Cu, Ni, Pb and Zn to Ceriodaphnia dubia, Pimephales Promelas, Hyalella azteca and Lumbriculus variegates

Environmental Toxicology and Chemistry. 12

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

42.4

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H. and C. Henderson

The acute toxicity of some heavy metals to different species of warmwater fishes

Air Wat. Pollut. Int. J. 10

2021/03/02

魚類

Poecilia reticulata (Guppy)

mortality

LC50

hours

mg/L

12 ECHA Information on Registered Substances

Khangarot, B.S. and P.K. Ray

Acute toxicity and toxic interaction of chromium and nickel to common guppy Poecilla reticulata (Peters).

Bull. Environ. Contam. Toxicol. 44

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

233

hours

1.3

mgNi/L

12 ECHA Information on Registered Substances

Blaylock, B.G. and M.L. Frank.

A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).

Bull. Environ. Contam. Toxicol. 21(4/5)

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

212

hours

2.14

mgNi/L

12 ECHA Information on Registered Substances

Blaylock, B.G. and M.L. Frank.

A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).

Bull. Environ. Contam. Toxicol. 21(4/5)

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

184

hours

3.18

mgNi/L

12 ECHA Information on Registered Substances

Blaylock, B.G. and M.L. Frank.

A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).

Bull. Environ. Contam. Toxicol. 21(4/5)

2021/03/02

魚類

Oncorhynchus mykiss (Rainbow trout)

Mortality

LC50

hours

35.5

mg/L

16 ECOTOX

Hale,J.G.

Toxicity of Metal Mining Wastes

Bull. Environ. Contam. Toxicol.17(1)

2020/11/12

魚類

Cyprinus carpio (Carp)

Mortality

LC50

hours

29100

μg/L

16 ECOTOX

Rehwoldt,R., G. Bida, and B. Nerrie

Acute Toxicity of Copper, Nickel, and Zinc Ions to Some Hudson River Fish Species

Bull. Environ. Contam. Toxicol.6(5)

2020/11/12

魚類

Cyprinus carpio (Carp)

Mortality

LC50

hours

10600

μg/L

16 ECOTOX

Rehwoldt,R., G. Bida, and B. Nerrie

Acute Toxicity of Copper, Nickel, and Zinc Ions to Some Hudson River Fish Species

Bull. Environ. Contam. Toxicol.6(5)

2020/11/12

魚類

Cyprinus carpio (Carp)

Mortality

LC50

hours

38200

μg/L

16 ECOTOX

Rehwoldt,R., G. Bida, and B. Nerrie

Acute Toxicity of Copper, Nickel, and Zinc Ions to Some Hudson River Fish Species

Bull. Environ. Contam. Toxicol.6(5)

2020/11/12

魚類

Pimephales promelas

LC50

hours

mg/L

12 ECHA Information on Registered Substances

Ewell, W.S., J.W. Gorsuch, R.O. Kringle, K.A. Robillard, and R.C. Spiegel

Simultaneous evaluation of the acute effects of chemicals on seven aquatic species

Environmental Toxicology and Chemistry. 5

2021/03/02

魚類

Poecilia reticulata (Guppy)

mortality

LC50

hours

mg/L

12 ECHA Information on Registered Substances

Khangarot, B.S. and P.K. Ray

Acute toxicity and toxic interaction of chromium and nickel to common guppy Poecilla reticulata (Peters).

Bull. Environ. Contam. Toxicol. 44

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

0.35

mg/L

12 ECHA Information on Registered Substances

Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl

The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas)

Water, Air, and Soil Pollution. 133

2021/03/02

魚類

Poecilia reticulata (Guppy)

mortality

LC50

hours

50.12

mg/L

12 ECHA Information on Registered Substances

Khangarot, B.S. and P.K. Ray

Acute toxicity and toxic interaction of chromium and nickel to common guppy Poecilla reticulata (Peters).

Bull. Environ. Contam. Toxicol. 44

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

3100

μg/L

12 ECHA Information on Registered Substances

Schubauer-Berigan, M.K., J.R. Dierkes, P.D. Monson, and G.T. Ankley

pH-Dependent toxicity of Cd, Cu, Ni, Pb and Zn to Ceriodaphnia dubia, Pimephales Promelas, Hyalella azteca and Lumbriculus variegates

Environmental Toxicology and Chemistry. 12

2021/03/02

魚類

Poecilia reticulata (Guppy)

mortality

LC50

168

hours

33.11

mg/L

12 ECHA Information on Registered Substances

Khangarot, B.S. and P.K. Ray

Acute toxicity and toxic interaction of chromium and nickel to common guppy Poecilla reticulata (Peters).

Bull. Environ. Contam. Toxicol. 44

2021/03/02

魚類

Poecilia reticulata (Guppy)

mortality

LC50

240

hours

31.15

mg/L

12 ECHA Information on Registered Substances

Khangarot, B.S. and P.K. Ray

Acute toxicity and toxic interaction of chromium and nickel to common guppy Poecilla reticulata (Peters).

Bull. Environ. Contam. Toxicol. 44

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

0.45

mg/L

12 ECHA Information on Registered Substances

Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl

The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas)

Water, Air, and Soil Pollution. 133

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

2.27

mg/L

12 ECHA Information on Registered Substances

Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl

The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas)

Water, Air, and Soil Pollution. 133

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

0.5

mg/L

12 ECHA Information on Registered Substances

Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl

The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas)

Water, Air, and Soil Pollution. 133

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

0.69

mg/L

12 ECHA Information on Registered Substances

Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl

The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas)

Water, Air, and Soil Pollution. 133

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

0.54

mg/L

12 ECHA Information on Registered Substances

Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl

The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas)

Water, Air, and Soil Pollution. 133

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H.

Chronic toxicity of nickel to the fathead minnow

J. Water Pollut. Control Fed. 46(4)

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

2.21

mg/L

12 ECHA Information on Registered Substances

Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl

The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas)

Water, Air, and Soil Pollution. 133

2021/03/02

魚類

Poecilia reticulata (Guppy)

mortality

LC50

hours

54.43

mg/L

12 ECHA Information on Registered Substances

Shuhaimi-Othman M, Yakub N, Ramle N-A, and Abas A.

Comparative toxicity of eight metals on freshwater fish.

Toxicology and Industrial Health; DOI

2021/03/02

魚類

Poecilia reticulata (Guppy)

mortality

LC50

hours

mg/L

12 ECHA Information on Registered Substances

Khangarot, B.S. and P.K. Ray

Acute toxicity and toxic interaction of chromium and nickel to common guppy Poecilla reticulata (Peters).

Bull. Environ. Contam. Toxicol. 44

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

44.5

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H. and C. Henderson

The acute toxicity of some heavy metals to different species of warmwater fishes

Air Wat. Pollut. Int. J. 10

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

hours

14.7

mg/L

12 ECHA Information on Registered Substances

Ghosh A, Kaviraj A, Saha S

Deposition, acute toxicity, and bioaccumulation of nickel in some freshwater organisms with best-fit functions modeling

Environ Sci Pollut Res 25

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

hours

27.88

mg/L

12 ECHA Information on Registered Substances

Ghosh A, Kaviraj A, Saha S

Deposition, acute toxicity, and bioaccumulation of nickel in some freshwater organisms with best-fit functions modeling

Environ Sci Pollut Res 25

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

hours

24.08

mg/L

12 ECHA Information on Registered Substances

Ghosh A, Kaviraj A, Saha S

Deposition, acute toxicity, and bioaccumulation of nickel in some freshwater organisms with best-fit functions modeling

Environ Sci Pollut Res 25

2021/03/02

魚類

Cyprinus carpio (Carp)

Mortality

LC50

hours

10.6

mgNi/L [nominal]

8 NITE 化学物質の初期リスク評価書

Rehwoldt, R., Bida, G. and Nerrie, B.

Acute toxicity of copper, nickel, and zinc Ions to some Hudson River fish species.

Bull.Environ.Contam.Toxicol., 6

2021/04/06

魚類

Pimephales promelas

LC50

hours

5～45

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H. and C. Henderson

The acute toxicity of some heavy metals to different species of warmwater fishes

Air Wat. Pollut. Int. J. 10

2021/03/02

魚類

Lepomis macrochirus

mortality

LC50

hours

110

mg/L

12 ECHA Information on Registered Substances

US EPA study

2021/03/02

魚類

Lepomis macrochirus

mortality

LC50

hours

170

mg/L

12 ECHA Information on Registered Substances

US EPA study

2021/03/02

魚類

Pimephales promelas

mortality

LC50

120

hours

0.6

mg/L

12 ECHA Information on Registered Substances

Krzykwa JC, Saeid A, Jeffries MKS

Identifying sublethal endpoints for evaluating neurotoxic compounds utilizing the fish embryo toxicity test

Ecotoxicology and Environmental Safety 170

2021/03/02

魚類

Lepomis macrochirus

mortality

LC50

hours

60.3

mg/L

12 ECHA Information on Registered Substances

US EPA study

2021/03/02

魚類

Lepomis macrochirus

mortality

NOEC

hours

mg/L

12 ECHA Information on Registered Substances

US EPA study

2021/03/02

魚類

Carassius auratus (Goldfish)

mortality

LC50

hours

34.1

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H. and C. Henderson

The acute toxicity of some heavy metals to different species of warmwater fishes

Air Wat. Pollut. Int. J. 10

2021/03/02

魚類

Lepomis macrochirus

mortality

LC50

hours

5.36

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H. and C. Henderson

The acute toxicity of some heavy metals to different species of warmwater fishes

Air Wat. Pollut. Int. J. 10

2021/03/02

魚類

Carassius auratus (Goldfish)

mortality

LC50

hours

20.5

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H. and C. Henderson

The acute toxicity of some heavy metals to different species of warmwater fishes

Air Wat. Pollut. Int. J. 10

2021/03/02

魚類

Carassius auratus (Goldfish)

mortality

LC50

hours

9.82

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H. and C. Henderson

The acute toxicity of some heavy metals to different species of warmwater fishes

Air Wat. Pollut. Int. J. 10

2021/03/02

魚類

Lepomis macrochirus

mortality

LC50

hours

41.7

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H. and C. Henderson

The acute toxicity of some heavy metals to different species of warmwater fishes

Air Wat. Pollut. Int. J. 10

2021/03/02

魚類

Lepomis macrochirus

mortality

NOEC

hours

mg/L

12 ECHA Information on Registered Substances

US EPA study

2021/03/02

魚類

Lepomis macrochirus

mortality

LC50

hours

62.2

mg/L

12 ECHA Information on Registered Substances

US EPA study

2021/03/02

魚類

Lepomis macrochirus

mortality

LC50

hours

115

mg/L

12 ECHA Information on Registered Substances

US EPA study

2021/03/02

魚類

Lepomis macrochirus

mortality

LC50

hours

170

mg/L

12 ECHA Information on Registered Substances

US EPA study

2021/03/02

魚類

Fundulus heteroclitus (Mummichog)

mortality

LC50

hours

55.3

mg/L

12 ECHA Information on Registered Substances

Bielmyer GK, DeCarlo C, Morris C, and Carrigan T.

The influence of salinity on acute nickel toxicity to the two euryhaline fish species, Fundulus heteroclitus and Kryptolebias marmoratus.

Environmental Toxicology and Chemistry; 32(6)

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

hours

38.76

mg/L

12 ECHA Information on Registered Substances

Ghosh A, Kaviraj A, Saha S

Deposition, acute toxicity, and bioaccumulation of nickel in some freshwater organisms with best-fit functions modeling

Environ Sci Pollut Res 25

2021/03/02

魚類

Lepomis macrochirus

mortality

LC50

hours

82.1

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H. and C. Henderson

The acute toxicity of some heavy metals to different species of warmwater fishes

Air Wat. Pollut. Int. J. 10

2021/03/02

魚類

Fundulus heteroclitus (Mummichog)

mortality

LC50

hours

45.2

mg/L

12 ECHA Information on Registered Substances

Bielmyer GK, DeCarlo C, Morris C, and Carrigan T.

The influence of salinity on acute nickel toxicity to the two euryhaline fish species, Fundulus heteroclitus and Kryptolebias marmoratus.

Environmental Toxicology and Chemistry; 32(6)

2021/03/02

魚類

Fundulus heteroclitus (Mummichog)

mortality

LC50

hours

24.8

mg/L

12 ECHA Information on Registered Substances

Bielmyer GK, DeCarlo C, Morris C, and Carrigan T.

The influence of salinity on acute nickel toxicity to the two euryhaline fish species, Fundulus heteroclitus and Kryptolebias marmoratus.

Environmental Toxicology and Chemistry; 32(6)

2021/03/02

魚類

Fundulus heteroclitus (Mummichog)

mortality

LC50

hours

13.1

mg/L

12 ECHA Information on Registered Substances

Bielmyer GK, DeCarlo C, Morris C, and Carrigan T.

The influence of salinity on acute nickel toxicity to the two euryhaline fish species, Fundulus heteroclitus and Kryptolebias marmoratus.

Environmental Toxicology and Chemistry; 32(6)

2021/03/02

魚類

Fundulus heteroclitus (Mummichog)

mortality

LC50

hours

12.3

mg/L

12 ECHA Information on Registered Substances

Bielmyer GK, DeCarlo C, Morris C, and Carrigan T.

The influence of salinity on acute nickel toxicity to the two euryhaline fish species, Fundulus heteroclitus and Kryptolebias marmoratus.

Environmental Toxicology and Chemistry; 32(6)

2021/03/02

魚類

Lepomis macrochirus

mortality

LC50

hours

5.18

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H. and C. Henderson

The acute toxicity of some heavy metals to different species of warmwater fishes

Air Wat. Pollut. Int. J. 10

2021/03/02

魚類

Pimephales promelas

enzyme activities

NOEC

days

>=1.8

μmol nickel/g tissue

12 ECHA Information on Registered Substances

publication

2021/03/02

魚類

Lepomis macrochirus

mortality

LC50

hours

11.3

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H. and C. Henderson

The acute toxicity of some heavy metals to different species of warmwater fishes

Air Wat. Pollut. Int. J. 10

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

hours

8.46

mg/L

12 ECHA Information on Registered Substances

Blaylock, B.G. and M.L. Frank.

A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).

Bull. Environ. Contam. Toxicol. 21(4/5)

2021/03/02

魚類

Lepomis macrochirus

mortality

LC50

hours

39.6

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H. and C. Henderson

The acute toxicity of some heavy metals to different species of warmwater fishes

Air Wat. Pollut. Int. J. 10

2021/03/02

魚類

Pimephales promelas

number of eggs/spawning and hatchability

LOEC

days

0.73

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H.

Chronic toxicity of nickel to the fathead minnow

J. Water Pollut. Control Fed. 46(4)

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

hours

2.3

mg/L

12 ECHA Information on Registered Substances

Alam, M.K. and O.E. Maughan

The effect of malathion, diazinon, and various concentrations of zinc, copper, nickel, lead, iron, and mercury on fish

Biological Trace Element Research. 34

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

hours

1.64

mg/L

12 ECHA Information on Registered Substances

Alam, M.K. and O.E. Maughan

The effect of malathion, diazinon, and various concentrations of zinc, copper, nickel, lead, iron, and mercury on fish

Biological Trace Element Research. 34

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

hours

1.3

mg/L

12 ECHA Information on Registered Substances

Alam, M.K. and O.E. Maughan

The effect of malathion, diazinon, and various concentrations of zinc, copper, nickel, lead, iron, and mercury on fish

Biological Trace Element Research. 34

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

hours

1.54

mg/L

12 ECHA Information on Registered Substances

Alam, M.K. and O.E. Maughan

The effect of malathion, diazinon, and various concentrations of zinc, copper, nickel, lead, iron, and mercury on fish

Biological Trace Element Research. 34

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

0.4

mg/L

12 ECHA Information on Registered Substances

Hoang, T.C., J.R. Tomasso, and S.J. Klaine

Influence of water quality and age on nickel toxicity to fathead minnows (Pimephales promelas)

Environ. Toxicol. Chem. Vol. 23, No. 1

2021/03/02

魚類

Carassius auratus (Goldfish)

LC50

2780

μg/L

12 ECHA Information on Registered Substances

Birge, W.J. and J.A. Black

Aquatic Toxicology of Nickel

In: Nickel in the Environment. J.O. Nriagu (ed.). Wiley. New York, NY.

2021/03/02

魚類

Carassius auratus (Goldfish)

LC10

414.4

μg/L

12 ECHA Information on Registered Substances

Birge, W.J. and J.A. Black

Aquatic Toxicology of Nickel

In: Nickel in the Environment. J.O. Nriagu (ed.). Wiley. New York, NY.

2021/03/02

魚類

Fundulus heteroclitus (Mummichog)

mortality

LC50

hours

>400

mg/L

12 ECHA Information on Registered Substances

Eisler, R. and R.J. Hennekey

Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna

Arch. Environ. Contam. Toxicol. 6

2021/03/02

魚類

Leuciscus idus (Orfe)

mortality

LC50

570

mg/L

12 ECHA Information on Registered Substances

other company data

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

1.68

mg/L

12 ECHA Information on Registered Substances

Hoang, T.C., J.R. Tomasso, and S.J. Klaine

Influence of water quality and age on nickel toxicity to fathead minnows (Pimephales promelas)

Environ. Toxicol. Chem. Vol. 23, No. 1

2021/03/02

魚類

Pimephales promelas

survival, growth, and reproduction

NOEC

days

<=0.38

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H.

Chronic toxicity of nickel to the fathead minnow

J. Water Pollut. Control Fed. 46(4)

2021/03/02

魚類

Lepomis macrochirus

mortality

LC50

hours

15.9

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H. and C. Henderson

The acute toxicity of some heavy metals to different species of warmwater fishes

Air Wat. Pollut. Int. J. 10

2021/03/02

魚類

Pimephales promelas

mortality and terata and length

NOEC

days

0.057

mg/L

12 ECHA Information on Registered Substances

Birge, W.J., J.A. Black, J.F. Hobson, A.G. Westerman, and T.M. Short

Toxicological studies on aquatic contaminants originating from coal production and utilization: The induction of tolerance to silver in laboratory populations of fish and the chronic toxicity of nickel to fish early life stages.

Water Resources Research Institute. Kentucky University, Lexington, KY. Research Report No. 151.

2021/03/02

魚類

Pimephales promelas

mortality and terata

LOEC

days

0.12

mg/L

12 ECHA Information on Registered Substances

Birge, W.J., J.A. Black, J.F. Hobson, A.G. Westerman, and T.M. Short

Water Resources Research Institute. Kentucky University, Lexington, KY. Research Report No. 151.

2021/03/02

魚類

Pimephales promelas

mortality

NOEC

days

108.9

μg/L

12 ECHA Information on Registered Substances

Lind, D., K. Alto, and S. Chatterton.

Regional Copper-Nickel Study: Aquatic Toxicology Study.

Minnesota Environmental Quality Board

2021/03/02

魚類

Pimephales promelas

mortality

LOEC

days

433.5

μg/L

12 ECHA Information on Registered Substances

Lind, D., K. Alto, and S. Chatterton.

Regional Copper-Nickel Study: Aquatic Toxicology Study.

Minnesota Environmental Quality Board

2021/03/02

魚類

Poecilia reticulata (Guppy)

mortality

LC50

hours

15.62

mg/L

12 ECHA Information on Registered Substances

Shuhaimi-Othman M, Yakub N, Ramle N-A, and Abas A.

Comparative toxicity of eight metals on freshwater fish.

Toxicology and Industrial Health; DOI

2021/03/02

魚類

Poecilia reticulata (Guppy)

mortality

LC50

hours

18.72

mg/L

12 ECHA Information on Registered Substances

Shuhaimi-Othman M, Yakub N, Ramle N-A, and Abas A.

Comparative toxicity of eight metals on freshwater fish.

Toxicology and Industrial Health; DOI

2021/03/02

魚類

Pimephales promelas

mortality

LD50 (hard water)

mg/L

12 ECHA Information on Registered Substances

other company data

2021/03/02

魚類

Fundulus heteroclitus (Mummichog)

LC100

168

hours

250

mg/L

12 ECHA Information on Registered Substances

Eisler, R. and R.J. Hennekey

Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna

Arch. Environ. Contam. Toxicol. 6

2021/03/02

魚類

Lepomis macrochirus

mortality

LC50

hours

8.67

mg/L

12 ECHA Information on Registered Substances

Pickering, Q.H. and C. Henderson

The acute toxicity of some heavy metals to different species of warmwater fishes

Air Wat. Pollut. Int. J. 10

2021/03/02

魚類

Fundulus heteroclitus (Mummichog)

mortality

LC100

hours

>400

mg/L

12 ECHA Information on Registered Substances

Eisler, R. and R.J. Hennekey

Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna

Arch. Environ. Contam. Toxicol. 6

2021/03/02

魚類

Fundulus heteroclitus (Mummichog)

mortality

LC50

hours

6.98

mg/L

12 ECHA Information on Registered Substances

Bielmyer GK, DeCarlo C, Morris C, and Carrigan T.

The influence of salinity on acute nickel toxicity to the two euryhaline fish species, Fundulus heteroclitus and Kryptolebias marmoratus.

Environmental Toxicology and Chemistry; 32(6)

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

hours

6.16

mg/L

12 ECHA Information on Registered Substances

Blaylock, B.G. and M.L. Frank.

A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).

Bull. Environ. Contam. Toxicol. 21(4/5)

2021/03/02

魚類

Fundulus heteroclitus (Mummichog)

NOEC

168

hours

mg/L

12 ECHA Information on Registered Substances

Eisler, R. and R.J. Hennekey

Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna

Arch. Environ. Contam. Toxicol. 6

2021/03/02

魚類

Fundulus heteroclitus (Mummichog)

LC50

168

hours

150

mg/L

12 ECHA Information on Registered Substances

Eisler, R. and R.J. Hennekey

Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna

Arch. Environ. Contam. Toxicol. 6

2021/03/02

魚類

Fundulus heteroclitus (Mummichog)

mortality

NOEC

hours

250

mg/L

12 ECHA Information on Registered Substances

Eisler, R. and R.J. Hennekey

Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna

Arch. Environ. Contam. Toxicol. 6

2021/03/02

魚類

Fundulus heteroclitus (Mummichog)

mortality

LC100

hours

400

mg/L

12 ECHA Information on Registered Substances

Eisler, R. and R.J. Hennekey

Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna

Arch. Environ. Contam. Toxicol. 6

2021/03/02

魚類

Fundulus heteroclitus (Mummichog)

mortality

LC50

hours

350

mg/L

12 ECHA Information on Registered Substances

Eisler, R. and R.J. Hennekey

Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna

Arch. Environ. Contam. Toxicol. 6

2021/03/02

魚類

Fundulus heteroclitus (Mummichog)

mortality

NOEC

hours

400

mg/L

12 ECHA Information on Registered Substances

Eisler, R. and R.J. Hennekey

Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna

Arch. Environ. Contam. Toxicol. 6

2021/03/02

魚類

Fundulus heteroclitus (Mummichog)

mortality

LC50

hours

2.7

mg/L

12 ECHA Information on Registered Substances

Bielmyer GK, DeCarlo C, Morris C, and Carrigan T.

The influence of salinity on acute nickel toxicity to the two euryhaline fish species, Fundulus heteroclitus and Kryptolebias marmoratus.

Environmental Toxicology and Chemistry; 32(6)

2021/03/02

魚類

Cyprinodon variegatus (Sheepshead minnow)

survival and growth (dry weight)

LOEC

days

40.6

mgNi/L

12 ECHA Information on Registered Substances

DeForest DK, Schlekat CE.

Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.

Integr Environ Assess Manag. 2013 Oct;9(4)

2021/03/02

魚類

Cyprinodon variegatus (Sheepshead minnow)

growth (dry weight)

IC20

days

23.5

mgNi/L

12 ECHA Information on Registered Substances

DeForest DK, Schlekat CE.

Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.

Integr Environ Assess Manag. 2013 Oct;9(4)

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

233

hours

1.3

mg/L

12 ECHA Information on Registered Substances

Blaylock, B.G. and M.L. Frank.

A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).

Bull. Environ. Contam. Toxicol. 21(4/5)

2021/03/02

魚類

Cyprinodon variegatus (Sheepshead minnow)

survival or growth (dry weight)

NOEC

days

21.7

mgNi/L

12 ECHA Information on Registered Substances

DeForest DK, Schlekat CE.

Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.

Integr Environ Assess Manag. 2013 Oct;9(4)

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

212

hours

2.14

mg/L

12 ECHA Information on Registered Substances

Blaylock, B.G. and M.L. Frank.

A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).

Bull. Environ. Contam. Toxicol. 21(4/5)

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

184

hours

3.18

mg/L

12 ECHA Information on Registered Substances

Blaylock, B.G. and M.L. Frank.

A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).

Bull. Environ. Contam. Toxicol. 21(4/5)

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

257

hours

0.75

mg/L

12 ECHA Information on Registered Substances

Blaylock, B.G. and M.L. Frank.

A comparison of the toxicity of nickel to the developing eggs and larvae of carp (Cyprinus carpio).

Bull. Environ. Contam. Toxicol. 21(4/5)

2021/03/02

魚類

Cyprinodon variegatus (Sheepshead minnow)

mortality

LC50

days

27.8

mgNi/L

12 ECHA Information on Registered Substances

DeForest DK, Schlekat CE.

Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.

Integr Environ Assess Manag. 2013 Oct;9(4)

2021/03/02

魚類

Cyprinodon variegatus (Sheepshead minnow)

growth (dry weight)

IC50

days

29.9

mgNi/L

12 ECHA Information on Registered Substances

DeForest DK, Schlekat CE.

Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.

Integr Environ Assess Manag. 2013 Oct;9(4)

2021/03/02

魚類

Cyprinodon variegatus (Sheepshead minnow)

growth (dry weight)

EC10

days

20.76

mgNi/L

12 ECHA Information on Registered Substances

DeForest DK, Schlekat CE.

Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.

Integr Environ Assess Manag. 2013 Oct;9(4)

2021/03/02

魚類

Pimephales promelas

mortality

LC50

days

0.7

mg/L

12 ECHA Information on Registered Substances

Krzykwa JC, Saeid A, Jeffries MKS

Identifying sublethal endpoints for evaluating neurotoxic compounds utilizing the fish embryo toxicity test

Ecotoxicology and Environmental Safety 170

2021/03/02

魚類

Pimephales promelas

time to hatch

LOEC

days

<=24.8

μg/L

○

12 ECHA Information on Registered Substances

publication

2021/03/02

魚類

Cyprinodon variegatus (Sheepshead minnow)

mortality

LC20

days

23.9

mgNi/L

12 ECHA Information on Registered Substances

DeForest DK, Schlekat CE.

Species sensitivity distribution evaluation for chronic nickel toxicity to marine organisms.

Integr Environ Assess Manag. 2013 Oct;9(4)

2021/03/02

化学物質有害性情報データベース 物質情報

化学物質有害性情報データベース物質情報