化学物質有害性情報データベース 物質情報

CAS 登録番号 CAS RN® ： 4098719
官報公示整理番号　METI No. ： 7-5
物質名 test material ： ３－イソシアナトメチル－３，５，５－トリメチルシクロヘキシル＝イソシアナート　／3-Isocyanatomethyl-3,5,5-trimethylcyclohexylisocyanate
水溶解度 water solubility ： 2.928mg/L (推計値 estimated)
LogKow ： 4.75 (推計値 estimated)
備考 remarks ：
Excelファイルダウンロード (XLS:19KB)

【注意事項】
* 化学物質有害性情報データベース情報更新日が2019年9月以前はRead-acrossデータでも○としていないので、毒性値の取り扱いには注意が必要である。

　　　 　　　 　　　 　　　 　　　 　　　
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) Read-across * QSAR GLP 設定濃度 実測濃度 情報源 情報源による信頼性評価 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure duration value exposure duration unit toxicity value toxicity unit Read-across QSAR GLPnominal concentration measured concentrationoriginal work type original work reliability rankauthor title referenced journal publication year Information update date
藻類 Desmodesmus subspicatus biomass EC50 72 hours >70 mg/L ○ 4 OECD SIDS (HPVC) 2 Bayer AG Investigation of the ecological properties of DESMODUR I. Bayer AG (Leverkusen) Report No. 860 A/99 with attachments (unpublished). 2000 2017/02/21
藻類 Desmodesmus subspicatus growth rate EC50 72 hours >70 mg/L ○ 4 OECD SIDS (HPVC) 2 Bayer AG Investigation of the ecological properties of DESMODUR I. Bayer AG (Leverkusen) Report No. 860 A/99 with attachments (unpublished). 2000 2017/02/21
藻類 Desmodesmus subspicatus growth rate EC50 72 hours 119 mg/L × 4 OECD SIDS (HPVC) 4 Hüls AG Algenwachstumshemmtest nach UBA (Stand Feb. 1984) - Scenedesmus subspicatus, Produkt Isophorondiisocyanat. Report No. AW 145/1+2 (unpublished, 1 p). 1988 2017/02/21
藻類 Desmodesmus subspicatus Growth：生長（速度法） EC50 3 days >70000 μg/L 6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価） 2 OECD High Production Volume Chemicals Program SIDS(Screening Information Data Set) Initial Assessment Report, 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate. Bayer AG (Leverkusen) Report No. 860 A/99 with attachments (unpublished). 2006 2017/01/23
藻類 Scenedesmus subspicatus EC50 72 hours 118.7 mg/L × 11 Japan チャレンジプログラム Huels Untersuchung 2017/01/30
藻類 Scenedesmus subspicatus 増殖阻害 EC50 72 hours 118.7 mg/L 18 既存化学物質安全性(ハザード)評価シート EU IUCLID(International Uniform Chemical Information Data Base)Data Set 2000 2016/02/26
藻類 Desmodesmus subspicatus growth rate EC50 72 hours 119 mg/L × 12 ECHA Information on Registered Substances 4 study report 1988 2017/02/27
藻類 Desmodesmus subspicatus growth rate EC50 72 hours >70 mg/L [TOC measurement] ○ 12 ECHA Information on Registered Substances 2 study report 2000 2017/02/27
藻類 Desmodesmus subspicatus growth rate NOEC 72 hours 4.4 mg/L ○ 4 OECD SIDS (HPVC) 2 Bayer AG Investigation of the ecological properties of DESMODUR I. Bayer AG (Leverkusen) Report No. 860 A/99 with attachments (unpublished). 2000 2017/02/21
藻類 Desmodesmus subspicatus growth rate LOEC 72 hours 8.8 mg/L ○ 4 OECD SIDS (HPVC) 2 Bayer AG Investigation of the ecological properties of DESMODUR I. Bayer AG (Leverkusen) Report No. 860 A/99 with attachments (unpublished). 2000 2017/02/21
藻類 Desmodesmus subspicatus biomass NOEC 72 hours >=70 mg/L ○ 4 OECD SIDS (HPVC) 2 Bayer AG Investigation of the ecological properties of DESMODUR I. Bayer AG (Leverkusen) Report No. 860 A/99 with attachments (unpublished). 2000 2017/02/21
藻類 Desmodesmus subspicatus biomass NOEC 72 hours >70 mg/L ○ 4 OECD SIDS (HPVC) 2 Bayer AG Investigation of the ecological properties of DESMODUR I. Bayer AG (Leverkusen) Report No. 860 A/99 with attachments (unpublished). 2000 2017/02/21
藻類 Desmodesmus subspicatus growth rate EC10 72 hours 19 mg/L × 4 OECD SIDS (HPVC) 4 Hüls AG Algenwachstumshemmtest nach UBA (Stand Feb. 1984) - Scenedesmus subspicatus, Produkt Isophorondiisocyanat. Report No. AW 145/1+2 (unpublished, 1 p). 1988 2017/02/21
藻類 Desmodesmus subspicatus Growth：生長（速度法） NOEC 3 days 4400 μg/L 6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価） 2 OECD High Production Volume Chemicals Program SIDS(Screening Information Data Set) Initial Assessment Report, 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate. Bayer AG (Leverkusen) Report No. 860 A/99 with attachments (unpublished). 2006 2017/01/23
藻類 Scenedesmus subspicatus EC10 72 hours 18.8 mg/L × 11 Japan チャレンジプログラム Huels Untersuchung 2017/01/30
藻類 Desmodesmus subspicatus growth rate EC10 72 hours 19 mg/L × 12 ECHA Information on Registered Substances 4 study report 1988 2017/02/27
藻類 Desmodesmus subspicatus growth rate LOEC 72 hours 8.8 mg/L [TOC measurement] ○ 12 ECHA Information on Registered Substances 2 study report 2000 2017/02/27
藻類 Desmodesmus subspicatus growth rate NOEC 72 hours 4.4 mg/L [TOC measurement] ○ 12 ECHA Information on Registered Substances 2 study report 2000 2017/02/27
甲殻類 Daphnia magna immobilization EC0 48 hours 18 mg/L ○ 4 OECD SIDS (HPVC) 2 Hüls AG Bestimmung der Auswirkungen von Vestanat IPDI auf das Schwimmverhalten von Daphnia magna. Report No. DK-654 (unpublished). 1995 2017/02/21
甲殻類 Daphnia magna immobilization EC50 48 hours >65 mg/L ○ 4 OECD SIDS (HPVC) 2 Hüls AG Bestimmung der Auswirkungen von Vestanat IPDI auf das Schwimmverhalten von Daphnia magna. Report No. DK-654 (unpublished). 1995 2017/02/21
甲殻類 Daphnia magna immobilization EC50 48 hours 27 mg/L ○ 4 OECD SIDS (HPVC) 2 Hüls AG Bestimmung der Auswirkungen von Vestanat IPDI auf das Schwimmverhalten von Daphnia magna. Report No. DK-654 (unpublished). 1995 2017/02/21
甲殻類 Daphnia magna Immobilization：遊泳阻害 EC50 2 days 27000 μg/L 6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価） 2 OECD High Production Volume Chemicals Program SIDS(Screening Information Data Set) Initial Assessment Report, 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate. Bayer AG (Leverkusen) Report No. 860 A/99 with attachments (unpublished). 2006 2017/01/23
甲殻類 Daphnia magna Immobilization：遊泳阻害 EC50 2 days 35000 μg/L 6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価） 2 OECD High Production Volume Chemicals Program SIDS(Screening Information Data Set) Initial Assessment Report, 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate. Bayer AG (Leverkusen) Report No. 860 A/99 with attachments (unpublished). 2006 2017/01/23
甲殻類 Daphnia magna immoble EC0 48 hours 19 mg/L ○ 4 OECD SIDS (HPVC) 2 Bayer AG Investigation of the ecological properties of DESMODUR I. Bayer AG (Leverkusen) Report No. 860 A/99 with attachments (unpublished). 2000 2017/02/21
甲殻類 Daphnia magna immoble EC0 24 hours 37 mg/L ○ 4 OECD SIDS (HPVC) 2 Bayer AG Investigation of the ecological properties of DESMODUR I. Bayer AG (Leverkusen) Report No. 860 A/99 with attachments (unpublished). 2000 2017/02/21
甲殻類 Daphnia magna immoble EC50 48 hours 35 mg/L ○ 4 OECD SIDS (HPVC) 2 Bayer AG Investigation of the ecological properties of DESMODUR I. Bayer AG (Leverkusen) Report No. 860 A/99 with attachments (unpublished). 2000 2017/02/21
甲殻類 Daphnia magna EC50 24 hours 84 mg/L ○ 4 OECD SIDS (HPVC) 4 Hüls AG Daphnientest nach DIN 38412 Teil 11, Produkt Isophorondiisocyanat. Report No. D-310a (unpublished, 1 p). 1988 2017/02/21
甲殻類 Daphnia magna immoble EC100 48 hours 73 mg/L ○ 4 OECD SIDS (HPVC) 2 Bayer AG Investigation of the ecological properties of DESMODUR I. Bayer AG (Leverkusen) Report No. 860 A/99 with attachments (unpublished). 2000 2017/02/21
甲殻類 Daphnia magna immoble EC100 24 hours >73 mg/L ○ 4 OECD SIDS (HPVC) 2 Bayer AG Investigation of the ecological properties of DESMODUR I. Bayer AG (Leverkusen) Report No. 860 A/99 with attachments (unpublished). 2000 2017/02/21
甲殻類 Daphnia magna EC50 24 hours 83.7 mg/L × 11 Japan チャレンジプログラム Huels Untersuchung 2017/01/30
甲殻類 Daphnia magna 遊泳阻害 EC50 24 hours 83.7 mg/L 18 既存化学物質安全性(ハザード)評価シート EU IUCLID(International Uniform Chemical Information Data Base)Data Set 2000 2016/02/26
甲殻類 Daphnia magna mobility EC50 24 hours 49 mg/L [dissolved] ○ 12 ECHA Information on Registered Substances 2 study report 1995 2017/02/27
甲殻類 Daphnia magna mobility EC0 48 hours 18 mg/L [dissolved] ○ 12 ECHA Information on Registered Substances 2 study report 1995 2017/02/27
甲殻類 Daphnia magna mobility EC100 48 hours >65 mg/L [dissolved] ○ 12 ECHA Information on Registered Substances 2 study report 1995 2017/02/27
甲殻類 Daphnia magna mobility EC100 48 hours 73 mg/L ○ 12 ECHA Information on Registered Substances 2 study report 2000 2017/02/27
甲殻類 Daphnia magna mobility EC0 48 hours 19 mg/L ○ 12 ECHA Information on Registered Substances 2 study report 2000 2017/02/27
甲殻類 Daphnia magna mobility EC50 48 hours 35 mg/L ○ 12 ECHA Information on Registered Substances 2 study report 2000 2017/02/27
甲殻類 Daphnia magna mobility EC50 24 hours 84 mg/L × 12 ECHA Information on Registered Substances 4 study report 1988 2017/02/27
甲殻類 Daphnia magna mobility EC50 48 hours 27 mg/L [dissolved] ○ 12 ECHA Information on Registered Substances 2 study report 1995 2017/02/27
甲殻類 Daphnia magna reproduction NOEC 21 days 3 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 1993 2017/02/27
甲殻類 Daphnia magna reproduction LOEC 21 days 10 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 1993 2017/02/27
魚類 Leuciscus idus (Orfe) mortality LC0 48 hours 1 mg/L × 4 OECD SIDS (HPVC) 4 ECB (European Commission - European Chemicals Bureau) IUCLID Dataset on 3-isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate, 18th February 2000 2017/02/21
魚類 Danio rerio (Zebrafish) mortality and visible effects (swimming behavior) LC50 96 hours >72 mg/L ○ 4 OECD SIDS (HPVC) 2 Bayer AG Investigation of the ecological properties of DESMODUR I. Bayer AG (Leverkusen) Report No. 860 A/99 with attachments (unpublished). 2000 2017/02/21
魚類 Danio rerio (Zebrafish) mortality and visible effects (swimming behavior) LC0 96 hours >=72 mg/L ○ 4 OECD SIDS (HPVC) 2 Bayer AG Investigation of the ecological properties of DESMODUR I. Bayer AG (Leverkusen) Report No. 860 A/99 with attachments (unpublished). 2000 2017/02/21
魚類 Cyprinus carpio (Carp) mortality LC50 96 hours >208 mg/L ○ 4 OECD SIDS (HPVC) 2 Hüls AG Bestimmung der akuten Wirkungen von Vestanat IPDI gegenüber Fischen. Report No. FK 1369 (unpublished) 1996 2017/02/21
魚類 Leuciscus idus (Orfe) mortality LC50 48 hours 1.8 mg/L × 4 OECD SIDS (HPVC) 4 ECB (European Commission - European Chemicals Bureau) IUCLID Dataset on 3-isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate, 18th February 2000 2017/02/21
魚類 Cyprinus carpio (Carp) Mortality：死亡 LC50 4 days >208000 μg/L 6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価） 2 OECD High Production Volume Chemicals Program SIDS(Screening Information Data Set) Initial Assessment Report, 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate. Bayer AG (Leverkusen) Report No. 860 A/99 with attachments (unpublished). 2006 2017/01/23
魚類 Cyprinus carpio (Carp) mortality LC0 96 hours >=208 mg/L ○ 4 OECD SIDS (HPVC) 2 Hüls AG Bestimmung der akuten Wirkungen von Vestanat IPDI gegenüber Fischen. Report No. FK 1369 (unpublished) 1996 2017/02/21
魚類 Danio rerio (Zebrafish) Mortality：死亡 LC50 4 days >72000 μg/L 6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価） 2 OECD High Production Volume Chemicals Program SIDS(Screening Information Data Set) Initial Assessment Report, 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate. Bayer AG (Leverkusen) Report No. 860 A/99 with attachments (unpublished). 2006 2017/01/23
魚類 Leuciscus idus (Orfe) LC50 48 hours 1.8 mg/L × 11 Japan チャレンジプログラム Huels Untersuchung 2017/01/30
魚類 Leuciscus idus (Orfe) LC0 48 hours 1 mg/L × 11 Japan チャレンジプログラム Huels Untersuchung 2017/01/30
魚類 Leuciscus idus (Orfe) LC50 48 hours 1.8 mg/L 18 既存化学物質安全性(ハザード)評価シート EU IUCLID(International Uniform Chemical Information Data Base)Data Set 2000 2016/02/26
魚類 Leuciscus idus (Orfe) LC50 48 hours 1.8 mg/L × 12 ECHA Information on Registered Substances 4 other company data 1993 2017/03/16
魚類 Danio rerio (Zebrafish) mortality LC50 96 hours >72 mg/L [TOC measurement] ○ 12 ECHA Information on Registered Substances 2 study report 2000 2017/02/27
魚類 Danio rerio (Zebrafish) mortality LC0 96 hours >=72 mg/L [TOC measurement] ○ 12 ECHA Information on Registered Substances 2 study report 2000 2017/02/27
魚類 Cyprinus carpio (Carp) mortality LC50 96 hours >208 mg/L [TOC measurement] ○ 12 ECHA Information on Registered Substances 2 study report 1996 2017/02/27
魚類 Leuciscus idus (Orfe) LC0 48 hours 1 mg/L × 12 ECHA Information on Registered Substances 4 other company data 1993 2017/03/16
魚類 Cyprinus carpio (Carp) mortality LC0 96 hours >=208 mg/L [TOC measurement] ○ 12 ECHA Information on Registered Substances 2 study report 1996 2017/02/27