化学物質有害性情報データベース 物質情報

CAS 登録番号 CAS RN® ： 6419198
官報公示整理番号　METI No. ： 2-615
物質名 test material ： ニトリロ　トリス　メチレン　ホスホン酸　／Phosphonic acid, [nitrilotris(methylene)]tris-
水溶解度 water solubility ： 1000000mg/L (実測値 measured)
LogKow ： -3.53 (実測値 measured)
備考 remarks ：
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【注意事項】
* 化学物質有害性情報データベース情報更新日が2019年9月以前はRead-acrossデータでも○としていないので、毒性値の取り扱いには注意が必要である。

　　　 　　　 　　　 　　　 　　　 　　　
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) Read-across * QSAR GLP 設定濃度 実測濃度 情報源 情報源による信頼性評価 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure duration value exposure duration unit toxicity value toxicity unit Read-across QSAR GLPnominal concentration measured concentrationoriginal work type original work reliability rankauthor title referenced journal publication year Information update date
藻類 Selenastrum capricornutum biomass EC50 96 hours 12.39～19.14 ○ 4 OECD SIDS (HPVC) 2 Monsanto Project No: 43-000-755.10-168. Determination of toxic and/or lethal effects of phosphonates on Selenastrum capricornutum as influenced by media, pH and hardness. Unpublished report for Monsanto Company, St Louis, MO. Monsanto Report No: MO ESC9271. 1992 2017/02/26
藻類 Selenastrum capricornutum biomass EC50 96 hours 19.6 mg/L [as active acid] × 4 OECD SIDS (HPVC) 4 Schowanek D. & Verstraete W. J.Environ.Quality 1991 2017/02/26
藻類 Chlorella sp. growth rate EC50 96 hours 100 mg/L × 4 OECD SIDS (HPVC) 4 IUCLID CD ROM CAS No: 6419-19-8. Monsanto report BN-76-0090c. 2000 2017/02/26
藻類 Selenastrum capricornutum biomass EC50 96 hours 33.88～62.81 ○ 4 OECD SIDS (HPVC) 2 Monsanto Project No: 43-000-755.10-168. Determination of toxic and/or lethal effects of phosphonates on Selenastrum capricornutum as influenced by media, pH and hardness. Unpublished report for Monsanto Company, St Louis, MO. Monsanto Report No: MO ESC9271. 1992 2017/02/26
藻類 Chlorella sp. EC50 14 days 20 mg/L × 4 OECD SIDS (HPVC) 4 IUCLID CD ROM CAS No: 6419-19-8. Monsanto unpublished studies report AB-79-1384338-2. 2000 2017/02/26
藻類 Pseudokirchneriella subcapitata biomass EC50 96 hours 12.39 mg/L ○ 12 ECHA Information on Registered Substances 2 study report 1992 2017/02/09
藻類 Anabaena sp. biomass LOEC 18 days 100 mg/L × 4 OECD SIDS (HPVC) 4 Monsanto Job Number: 03-000-760, 117031-K3. Project No: MO-76-347. Dequest - Algae Part II. Unpublished progress report for Monsanto Company, St Louis, MO. 1972 2017/02/26
藻類 Chlorella sp. biomass LOEC 18 days 10 mg/L × 4 OECD SIDS (HPVC) 4 Monsanto Job Number: 03-000-760, 117031-K3. Project No: MO-76-347. Dequest - Algae Part II. Unpublished progress report for Monsanto Company, St Louis, MO. 1972 2017/02/26
藻類 Selenastrum capricornutum NOEC 14 days 100 mg/L 4 OECD SIDS (HPVC) 4 Schöberl P. and Huber L. Ökologisch relevante Daten von nichttensidischen Inhaltsstoffen in Wasch- und Reinigungsmitteln. Tenside Surfactants Detergents 1988 2017/02/26
藻類 Anabaena sp. biomass NOEC 18 days 10 mg/L × 4 OECD SIDS (HPVC) 4 Monsanto Job Number: 03-000-760, 117031-K3. Project No: MO-76-347. Dequest - Algae Part II. Unpublished progress report for Monsanto Company, St Louis, MO. 1972 2017/02/26
藻類 Selenastrum sp. biomass NOEC 18 days <10 mg/L × 4 OECD SIDS (HPVC) 4 Monsanto Job Number: 03-000-760, 117031-K3. Project No: MO-76-347. Dequest - Algae Part II. Unpublished progress report for Monsanto Company, St Louis, MO. 1972 2017/02/26
藻類 Selenastrum capricornutum biomass NOEC 96 hours 7.4 mg/L [as active acid] × 4 OECD SIDS (HPVC) 4 IUCLID CD ROM CAS No: 6419-19-8. Monsanto report BN-76-0090c. 2000 2017/02/26
藻類 Selenastrum capricornutum LOEC 14 days 300 mg/L 4 OECD SIDS (HPVC) 4 Schöberl P. and Huber L. Ökologisch relevante Daten von nichttensidischen Inhaltsstoffen in Wasch- und Reinigungsmitteln. Tenside Surfactants Detergents 1988 2017/02/26
藻類 Chlorella sp. biomass NOEC 18 days <10 mg/L × 4 OECD SIDS (HPVC) 4 Monsanto Job Number: 03-000-760, 117031-K3. Project No: MO-76-347. Dequest - Algae Part II. Unpublished progress report for Monsanto Company, St Louis, MO. 1972 2017/02/26
藻類 Selenastrum sp. biomass LOEC 18 days 10 mg/L × 4 OECD SIDS (HPVC) 4 Monsanto Job Number: 03-000-760, 117031-K3. Project No: MO-76-347. Dequest - Algae Part II. Unpublished progress report for Monsanto Company, St Louis, MO. 1972 2017/02/26
藻類 Selenastrum sp. biomass NOEC 18 days <10 mg/L × 12 ECHA Information on Registered Substances 2 study report 1972 2017/02/09
藻類 Anabaena sp. biomass LOEC 18 days 100 mg/L × 12 ECHA Information on Registered Substances 2 study report 1972 2017/02/09
藻類 Chlorella sp. biomass NOEC 18 days <10 mg/L × 12 ECHA Information on Registered Substances 2 study report 1972 2017/02/09
藻類 Chlorella sp. biomass LOEC 18 days 10 mg/L × 12 ECHA Information on Registered Substances 2 study report 1972 2017/02/09
藻類 Selenastrum sp. biomass LOEC 18 days 10 mg/L × 12 ECHA Information on Registered Substances 2 study report 1972 2017/02/09
藻類 Pseudokirchneriella subcapitata LOEC 14 days 300 mg/L 12 ECHA Information on Registered Substances 4 Schöberl P, Huber L Ökologisch relevante Daten von nichttensidischen Inhaltsstoffen in Wasch- und Reinigungsmitteln. Tenside Surfactants Detergents 1988 2017/02/09
藻類 Pseudokirchneriella subcapitata NOEC 14 days 100 mg/L 12 ECHA Information on Registered Substances 4 Schöberl P, Huber L Ökologisch relevante Daten von nichttensidischen Inhaltsstoffen in Wasch- und Reinigungsmitteln. Tenside Surfactants Detergents 1988 2017/02/09
藻類 Anabaena sp. biomass NOEC 18 days 10 mg/L × 12 ECHA Information on Registered Substances 2 study report 1972 2017/02/09
藻類 Selenastrum sp. cell number NOEC 14 days 100 mg/L ○ 12 ECHA Information on Registered Substances 4 grey literature 1984 2017/02/09
藻類 Pseudokirchneriella subcapitata biomass EC50 14 days 19.6 mg/L × 12 ECHA Information on Registered Substances 2 study report 1980 2017/02/09
藻類 Pseudokirchneriella subcapitata biomass NOEC 14 days 7.4 mg/L × 12 ECHA Information on Registered Substances 2 study report 1980 2017/02/09
甲殻類 Daphnia magna EC0 24 hours 150 mg/L × 4 OECD SIDS (HPVC) 2 Henkel Aminotris(methylen-phosphonsaeure) (CA 3) Pruefung auf allergieausloesende Eigenschaften am Meerschweinchen Abschlussbericht. Henkel Institut fuer Toxicologie, January 1984 1984 2017/02/26
甲殻類 Daphnia magna EC50 48 hours 297 mg/L × 4 OECD SIDS (HPVC) 2 Monsanto Acute toxicity of Dequest 2000, 2010, 2041, 2051 and 2060 to Daphnia magna. Unpublished report for Monsanto Company, St Louis, MO. Monsanto Report No: ES-81-SS-13. 1981 2017/02/26
甲殻類 Daphnia magna EC50 48 hours 833 mg/L × 4 OECD SIDS (HPVC) 4 Monsanto Job No: 45-000-760.40-6956000. Acute and chronic toxicity tests on Daphnia with DEQUEST Phosphonates. Unpublished report for Monsanto Company, St Louis, MO. Monsanto Report No: MO-77-0468-0469. 1976 2017/02/26
甲殻類 Daphnia magna EC50 24 hours 188 mg/L × 4 OECD SIDS (HPVC) 2 Henkel Aminotris(methylen-phosphonsaeure) (CA 3) Pruefung auf allergieausloesende Eigenschaften am Meerschweinchen Abschlussbericht. Henkel Institut fuer Toxicologie, January 1984 1984 2017/02/26
甲殻類 Daphnia magna EC50 24 hours 1182 mg/L × 4 OECD SIDS (HPVC) 4 Monsanto Job No: 45-000-760.40-6956000. Acute and chronic toxicity tests on Daphnia with DEQUEST Phosphonates. Unpublished report for Monsanto Company, St Louis, MO. Monsanto Report No: MO-77-0468-0469. 1976 2017/02/26
甲殻類 Daphnia magna EC100 24 hours 225 mg/L × 4 OECD SIDS (HPVC) 2 Henkel Aminotris(methylen-phosphonsaeure) (CA 3) Pruefung auf allergieausloesende Eigenschaften am Meerschweinchen Abschlussbericht. Henkel Institut fuer Toxicologie, January 1984 1984 2017/02/26
甲殻類 Daphnia magna immobility EC50 24 hours 375 mg/L [act. ingr.] × 12 ECHA Information on Registered Substances 4 study report 1972 2017/02/09
甲殻類 Daphnia magna EC0 24 hours 300 mg/L × 12 ECHA Information on Registered Substances 4 study report 1972 2017/02/09
甲殻類 Daphnia magna immobility EC50 48 hours 297 mg/L [act. ingr.] × 12 ECHA Information on Registered Substances 2 study report 1981 2017/02/09
甲殻類 Daphnia magna EC50 48 hours 833 mg/L × 12 ECHA Information on Registered Substances 4 study report 1976 2017/02/09
甲殻類 Daphnia magna EC100 24 hours 450 mg/L × 12 ECHA Information on Registered Substances 4 study report 1972 2017/02/09
甲殻類 Daphnia magna EC0 24 hours 300 mg/L 12 ECHA Information on Registered Substances 4 Schöberl P, Huber L Ökologisch relevante Daten von nichttensidischen Inhaltsstoffen in Wasch- und Reinigungsmitteln. Tenside Surfactants Detergents 1988 2017/02/09
甲殻類 Daphnia magna mobility EC50 48 hours 883 mg/L [act. ingr.] 12 ECHA Information on Registered Substances 4 study report 1976 2017/02/09
甲殻類 Daphnia magna immobility EC50 24 hours 545 mg/L [act. ingr.] × 12 ECHA Information on Registered Substances 2 study report 1981 2017/02/09
甲殻類 Daphnia magna NOEC 48 hours 125 mg/L × 4 OECD SIDS (HPVC) 2 Monsanto Acute toxicity of Dequest 2000, 2010, 2041, 2051 and 2060 to Daphnia magna. Unpublished report for Monsanto Company, St Louis, MO. Monsanto Report No: ES-81-SS-13. 1981 2017/02/26
甲殻類 Daphnia magna immobility NOEC 48 hours 125 mg/L [act. ingr.] × 12 ECHA Information on Registered Substances 2 study report 1981 2017/02/09
甲殻類 Daphnia magna NOEC 21 days 3 mg/L × 12 ECHA Information on Registered Substances 4 grey literature 1984 2017/02/09
甲殻類 Daphnia magna adult survival and reproduction (no. of offspring) NOEC 28 days >=25 mg/L [act. ingr.] 12 ECHA Information on Registered Substances 2 study report 1976 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours >330 mg/L × 4 OECD SIDS (HPVC) 2 Industrial BIO-TEST laboratories Inc. Request No BTL-71-51. Four-day static fish toxicity studies with Dequest 2000 in rainbow trout and bluegills. Unpublished report for Monsanto Company, St Louis, MO. Monsanto Report No: BT-71-0051. 1972 2017/02/26
魚類 Leuciscus idus (Orfe) LC0 48 hours 125 mg/L × 4 OECD SIDS (HPVC) 4 Henkel KGaA Unpublished data, Archive No.830091. Cited in European Chemicals Bureau IUCLID data sheet for CAS No 6419-19-8 1983 2017/02/26
魚類 Lepomis macrochirus (Bluegill) LC50 96 hours >330 mg/L × 4 OECD SIDS (HPVC) 2 Industrial BIO-TEST laboratories Inc. Request No BTL-71-51. Four-day static fish toxicity studies with Dequest 2000 in rainbow trout and bluegills. Unpublished report for Monsanto Company, St Louis, MO. Monsanto Report No: BT-71-0051. 1972 2017/02/26
魚類 Leuciscus idus (Orfe) LC0 48 hours 191 mg/L [as active acid] × 4 OECD SIDS (HPVC) 4 Kastner, W. von and Gode, P. Method und Ergebnisse bei der toxicologischen und okologischen Prufung von Wasserbehandlungsmitteln. Z. Wasser Abwasser Forsch. 1983 2017/02/26
魚類 Leuciscus idus (Orfe) LC50 48 hours 250 mg/L [as active acid] × 4 OECD SIDS (HPVC) 4 Kastner, W. von and Gode, P. Method und Ergebnisse bei der toxicologischen und okologischen Prufung von Wasserbehandlungsmitteln. Z. Wasser Abwasser Forsch. 1983 2017/02/26
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 14 days 150 mg/L ○ 4 OECD SIDS (HPVC) 1 ABC Dynamic toxicity of Dequest 2000 (AB-79-1384338-1) in Rainbow Trout (Salmo gairdneri). Unpublished report for Monsanto Chemical Company, St Louis MO. Monsanto Report No: AB-79-0191. 1979 2017/02/26
魚類 Leuciscus idus (Orfe) LC0 48 hours 191 mg/L × 12 ECHA Information on Registered Substances 4 Kastner W von, Gode P Method und Ergebnisse bei der toxicologischen und okologischen Prufung von Wasserbehandlungsmitteln. Z. Wasser Abwasser Forsch. 1983 2017/02/09
魚類 Cyprinodon variegatus (Sheepshead minnow) LC0 96 hours 8132 mg/L × 12 ECHA Information on Registered Substances 2 study report 1976 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours >330 mg/L × 12 ECHA Information on Registered Substances 2 study report 1972 2017/02/09
魚類 Leuciscus idus (Orfe) LC50 48 hours 250 mg/L × 12 ECHA Information on Registered Substances 4 Kastner W von, Gode P Method und Ergebnisse bei der toxicologischen und okologischen Prufung von Wasserbehandlungsmitteln. Z. Wasser Abwasser Forsch. 1983 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 14 days 150 mg/L [act. ingr.] ○ 12 ECHA Information on Registered Substances 1 study report 1979 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 96 hours 160 mg/L [act. ingr.] ○ 12 ECHA Information on Registered Substances 1 study report 1979 2017/02/09
魚類 Lepomis macrochirus (Bluegill) LC50 96 hours >330 mg/L × 12 ECHA Information on Registered Substances 2 study report 1972 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) NOEC 14 days 47 mg/L ○ 4 OECD SIDS (HPVC) 1 ABC Dynamic toxicity of Dequest 2000 (AB-79-1384338-1) in Rainbow Trout (Salmo gairdneri). Unpublished report for Monsanto Chemical Company, St Louis MO. Monsanto Report No: AB-79-0191. 1979 2017/02/26
魚類 Lepomis macrochirus (Bluegill) NOEC 96 hours 330 mg/L × 4 OECD SIDS (HPVC) 2 Industrial BIO-TEST laboratories Inc. Request No BTL-71-51. Four-day static fish toxicity studies with Dequest 2000 in rainbow trout and bluegills. Unpublished report for Monsanto Company, St Louis, MO. Monsanto Report No: BT-71-0051. 1972 2017/02/26
魚類 Oncorhynchus mykiss (Rainbow trout) NOEC 96 hours 330 mg/L × 4 OECD SIDS (HPVC) 2 Industrial BIO-TEST laboratories Inc. Request No BTL-71-51. Four-day static fish toxicity studies with Dequest 2000 in rainbow trout and bluegills. Unpublished report for Monsanto Company, St Louis, MO. Monsanto Report No: BT-71-0051. 1972 2017/02/26
魚類 Leuciscus idus (Orfe) NOEC 48 hours 150 mg/L [as active acid] × 4 OECD SIDS (HPVC) 4 Kastner, W. von and Gode, P. Method und Ergebnisse bei der toxicologischen und okologischen Prufung von Wasserbehandlungsmitteln. Z. Wasser Abwasser Forsch. 1983 2017/02/26
魚類 Oncorhynchus mykiss (Rainbow trout) mortality NOEC 14 days 47 mg/L [act. ingr.] ○ 12 ECHA Information on Registered Substances 1 study report 1979 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) length and weight of fry LOEC 60 days 47.6 mg/L [act. ingr.] ○ 12 ECHA Information on Registered Substances 1 study report 1980 2017/02/09
魚類 Lepomis macrochirus (Bluegill) NOEC 96 hours 330 mg/L × 12 ECHA Information on Registered Substances 2 study report 1972 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) NOEC 96 hours 330 mg/L × 12 ECHA Information on Registered Substances 2 study report 1972 2017/02/09
魚類 Leuciscus idus (Orfe) NOEC 48 hours 150 mg/L × 12 ECHA Information on Registered Substances 4 Kastner W von, Gode P Method und Ergebnisse bei der toxicologischen und okologischen Prufung von Wasserbehandlungsmitteln. Z. Wasser Abwasser Forsch. 1983 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) length and weight of fry NOEC 60 days 23 mg/L [act. ingr.] ○ 12 ECHA Information on Registered Substances 1 study report 1980 2017/02/09
魚類 Cyprinodon variegatus (Sheepshead minnow) NOEC 96 hours 4831 mg/L × 12 ECHA Information on Registered Substances 2 study report 1976 2017/02/09