化学物質有害性情報データベース 物質情報

CAS 登録番号 CAS RN® : 75058
官報公示整理番号 METI No. : 2-1763
物質名 test material : アセトニトリル /Acetonitrile
水溶解度 water solubility : 136700mg/L (実測値 measured)
LogKow : -0.34 (実測値 measured)
備考 remarks
Excelファイルダウンロード (XLS:19KB)

【注意事項】
* 化学物質有害性情報データベース情報更新日が2019年9月以前はRead-acrossデータでも○としていないので、毒性値の取り扱いには注意が必要である。

                       
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) Read-across * QSAR GLP 設定濃度 実測濃度 情報源 情報源による信頼性評価 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure duration value exposure duration unit toxicity value toxicity unit Read-across QSAR GLPnominal concentration measured concentrationoriginal work type original work reliability rankauthor title referenced journal publication year Information update date
藻類 Pseudokirchneriella subcapitata Population EC50 2 days 7943000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Chen,C.Y., S.L. Chen, and E.R. Christensen Individual and Combined Toxicity of Nitriles and Aldehydes to Raphidocelis subcapitata Environ. Toxicol. Chem.24(5): 1067-1073 2005 2016/03/25
藻類 Pseudokirchneriella subcapitata Physiology EC50 2 days 5926000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Chen,C.Y., S.L. Chen, and E.R. Christensen Individual and Combined Toxicity of Nitriles and Aldehydes to Raphidocelis subcapitata Environ. Toxicol. Chem.24(5): 1067-1073 2005 2016/03/25
甲殻類 Daphnia magna Reproduction NOEC 21 days 160000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tong,Z., Z. Huailan, and J. Hongjun Chronic Toxicity of Acrylonitrile and Acetonitrile to Daphnia magna in 14-d and 21-d Toxicity Tests Bull. Environ. Contam. Toxicol.57(4): 655-659 1996 2016/03/25
甲殻類 Daphnia magna Mortality LOEC 14 days >130000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tong,Z., Z. Huailan, and J. Hongjun Chronic Toxicity of Acrylonitrile and Acetonitrile to Daphnia magna in 14-d and 21-d Toxicity Tests Bull. Environ. Contam. Toxicol.57(4): 655-659 1996 2016/03/25
甲殻類 Daphnia magna Mortality 14 days >900000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tong,Z., Z. Huailan, and J. Hongjun Chronic Toxicity of Acrylonitrile and Acetonitrile to Daphnia magna in 14-d and 21-d Toxicity Tests Bull. Environ. Contam. Toxicol.57(4): 655-659 1996 2016/03/25
甲殻類 Daphnia magna Reproduction 21 days 230000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tong,Z., Z. Huailan, and J. Hongjun Chronic Toxicity of Acrylonitrile and Acetonitrile to Daphnia magna in 14-d and 21-d Toxicity Tests Bull. Environ. Contam. Toxicol.57(4): 655-659 1996 2016/03/25
甲殻類 Daphnia magna Reproduction 14 days 230000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tong,Z., Z. Huailan, and J. Hongjun Chronic Toxicity of Acrylonitrile and Acetonitrile to Daphnia magna in 14-d and 21-d Toxicity Tests Bull. Environ. Contam. Toxicol.57(4): 655-659 1996 2016/03/25
甲殻類 Daphnia magna Mortality 21 days >900000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tong,Z., Z. Huailan, and J. Hongjun Chronic Toxicity of Acrylonitrile and Acetonitrile to Daphnia magna in 14-d and 21-d Toxicity Tests Bull. Environ. Contam. Toxicol.57(4): 655-659 1996 2016/03/25
甲殻類 Daphnia magna Physiology LC50 1 days >10000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuhn Results of the Damaging Effect of Water Pollutants on Daphnia magna (Befunde der Schadwirkung Wassergefahrdender Stoffe Gegen Daphnia magna) TR-79-1204, Literature Research Company, Annandale, VA:26 p. 1977 2016/03/25
甲殻類 Daphnia magna Reproduction NOEC 14 days 160000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tong,Z., Z. Huailan, and J. Hongjun Chronic Toxicity of Acrylonitrile and Acetonitrile to Daphnia magna in 14-d and 21-d Toxicity Tests Bull. Environ. Contam. Toxicol.57(4): 655-659 1996 2016/03/25
甲殻類 Daphnia magna Mortality LC50 4 days >100000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Ewell,W.S., J.W. Gorsuch, R.O. Kringle, K.A. Robillard, and R.C. Spiegel Simultaneous Evaluation of the Acute Effects of Chemicals on Seven Aquatic Species Environ. Toxicol. Chem.5(9): 831-840 1986 2016/03/25
甲殻類 Daphnia magna Mortality LC50 2 days 3600000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tong,Z., Z. Huailan, and J. Hongjun Chronic Toxicity of Acrylonitrile and Acetonitrile to Daphnia magna in 14-d and 21-d Toxicity Tests Bull. Environ. Contam. Toxicol.57(4): 655-659 1996 2016/03/25
甲殻類 Daphnia magna Mortality NOEC 14 days 640000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tong,Z., Z. Huailan, and J. Hongjun Chronic Toxicity of Acrylonitrile and Acetonitrile to Daphnia magna in 14-d and 21-d Toxicity Tests Bull. Environ. Contam. Toxicol.57(4): 655-659 1996 2016/03/25
甲殻類 Daphnia magna Behavior EC50 1 days >10000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuehn Results of Toxic Action of Water Pollutants on Daphnia magna Straus Tested by an Improved Standardized Procedure Z. Wasser-Abwasser-Forsch.15(1): 1-6 1982 2016/03/25
甲殻類 Daphnia magna Mortality LOEC 21 days >1300000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tong,Z., Z. Huailan, and J. Hongjun Chronic Toxicity of Acrylonitrile and Acetonitrile to Daphnia magna in 14-d and 21-d Toxicity Tests Bull. Environ. Contam. Toxicol.57(4): 655-659 1996 2016/03/25
甲殻類 Daphnia magna Reproduction LOEC 21 days 320000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tong,Z., Z. Huailan, and J. Hongjun Chronic Toxicity of Acrylonitrile and Acetonitrile to Daphnia magna in 14-d and 21-d Toxicity Tests Bull. Environ. Contam. Toxicol.57(4): 655-659 1996 2016/03/25
甲殻類 Daphnia magna Mortality LOEC 14 days >130000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tong,Z., Z. Huailan, and J. Hongjun Chronic Toxicity of Acrylonitrile and Acetonitrile to Daphnia magna in 14-d and 21-d Toxicity Tests Bull. Environ. Contam. Toxicol.57(4): 655-659 1996 2016/03/25
甲殻類 Daphnia magna Reproduction LOEC 14 days 320000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tong,Z., Z. Huailan, and J. Hongjun Chronic Toxicity of Acrylonitrile and Acetonitrile to Daphnia magna in 14-d and 21-d Toxicity Tests Bull. Environ. Contam. Toxicol.57(4): 655-659 1996 2016/03/25
甲殻類 Daphnia magna Behavior EC0 1 days 5000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuehn Results of Toxic Action of Water Pollutants on Daphnia magna Straus Tested by an Improved Standardized Procedure Z. Wasser-Abwasser-Forsch.15(1): 1-6 1982 2016/03/25
甲殻類 Daphnia sp. Dapnia pulex LC50 18 hours 5838 mg/L 7 EU Risk Assessment Report (EUリスク評価書) Bownan et al. 1981 2016/02/22
甲殻類 Daphnia magna LC50 24 hours >10000 mg/L 7 EU Risk Assessment Report (EUリスク評価書) Bringmann G and Kühn R Threshold values for the harmful effect of water pollulants on bacteria (Pseudomonas putida) and green algae (Scenedesmus quadricauda) in the cell reproduction inhibition test). Z. Wasser Abwasser Forsch, 10 1977 2016/02/22
甲殻類 Daphnia magna LC50 96 hours >100 mg/L 7 EU Risk Assessment Report (EUリスク評価書) Ewell WS et al. Environ. Toxic. Chem 5 1986 2016/02/22
甲殻類 Daphnia magna Mortality LC50 48 hours 3580 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Peter C. von der Ohe, Ralph Kühne, Ralf-Uwe Ebert, Rolf Altenburger, Matthias Liess, and Gerrit Schüürmann Structural Alerts-A New Classification Model to Discriminate Excess Toxicity from Narcotic Effect Levels of Organic Compounds in the Acute Daphnid Assay 2005 2016/02/08
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 4 days 1850000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Henderson,C., Q.H. Pickering, and A.E. Lemke The Effect of Some Organic Cyanides (Nitriles) on Fish In: Proc. 15th Ind. Waste Conf. , Eng. Bull. Purdue Univ. , Ser. No. 106 65(2): 120-130 1961 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days >100000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Ewell,W.S., J.W. Gorsuch, R.O. Kringle, K.A. Robillard, and R.C. Spiegel Simultaneous Evaluation of the Acute Effects of Chemicals on Seven Aquatic Species Environ. Toxicol. Chem.5(9): 831-840 1986 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 1000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Henderson,C., Q.H. Pickering, and A.E. Lemke The Effect of Some Organic Cyanides (Nitriles) on Fish In: Proc. 15th Ind. Waste Conf. , Eng. Bull. Purdue Univ. , Ser. No. 106 65(2): 120-130 1961 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 2 days 1050000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Henderson,C., Q.H. Pickering, and A.E. Lemke The Effect of Some Organic Cyanides (Nitriles) on Fish In: Proc. 15th Ind. Waste Conf. , Eng. Bull. Purdue Univ. , Ser. No. 106 65(2): 120-130 1961 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 2 days 1000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tonogai,Y., S. Ogawa, Y. Ito, and M. Iwaida Actual Survey on TLM (Median Tolerance Limit) Values of Environmental Pollutants, Especially on Amines, Nitriles, Aromatic Nitrogen Compounds J. Toxicol. Sci.7(3): 193-203 1982 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 1 days 1000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tonogai,Y., S. Ogawa, Y. Ito, and M. Iwaida Actual Survey on TLM (Median Tolerance Limit) Values of Environmental Pollutants, Especially on Amines, Nitriles, Aromatic Nitrogen Compounds J. Toxicol. Sci.7(3): 193-203 1982 2016/03/25
魚類 Poecilia reticulata (Guppy) Physiology 3 days 10000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Jones,W.E. Detection of Pollutants by Fish Tests Water Treat. Exam.24:132-139 1975 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 1 days 1150000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Henderson,C., Q.H. Pickering, and A.E. Lemke The Effect of Some Organic Cyanides (Nitriles) on Fish In: Proc. 15th Ind. Waste Conf. , Eng. Bull. Purdue Univ. , Ser. No. 106 65(2): 120-130 1961 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 1 days 1850000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Henderson,C., Q.H. Pickering, and A.E. Lemke The Effect of Some Organic Cyanides (Nitriles) on Fish In: Proc. 15th Ind. Waste Conf. , Eng. Bull. Purdue Univ. , Ser. No. 106 65(2): 120-130 1961 2016/03/25
魚類 Poecilia reticulata (Guppy) Mortality LC50 4 days 1650000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Henderson,C., Q.H. Pickering, and A.E. Lemke The Effect of Some Organic Cyanides (Nitriles) on Fish In: Proc. 15th Ind. Waste Conf. , Eng. Bull. Purdue Univ. , Ser. No. 106 65(2): 120-130 1961 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 1640000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Brooke,L.T., D.J. Call, D.L. Geiger, and C.E. Northcott Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales promelas), Vol. 1 Center for Lake Superior Environmental Studies, University of Wisconsin-Superior, Superior, WI:414 p. 1984 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 1 days 1050000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Henderson,C., Q.H. Pickering, and A.E. Lemke The Effect of Some Organic Cyanides (Nitriles) on Fish In: Proc. 15th Ind. Waste Conf. , Eng. Bull. Purdue Univ. , Ser. No. 106 65(2): 120-130 1961 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 1000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Henderson,C., Q.H. Pickering, and A.E. Lemke The Effect of Some Organic Cyanides (Nitriles) on Fish In: Proc. 15th Ind. Waste Conf. , Eng. Bull. Purdue Univ. , Ser. No. 106 65(2): 120-130 1961 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 2 days 1000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Henderson,C., Q.H. Pickering, and A.E. Lemke The Effect of Some Organic Cyanides (Nitriles) on Fish In: Proc. 15th Ind. Waste Conf. , Eng. Bull. Purdue Univ. , Ser. No. 106 65(2): 120-130 1961 2016/03/25
魚類 Poecilia reticulata (Guppy) Mortality LC50 1 days 1650000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Henderson,C., Q.H. Pickering, and A.E. Lemke The Effect of Some Organic Cyanides (Nitriles) on Fish In: Proc. 15th Ind. Waste Conf. , Eng. Bull. Purdue Univ. , Ser. No. 106 65(2): 120-130 1961 2016/03/25
魚類 Poecilia reticulata (Guppy) LC50 1650 mg/L 7 EU Risk Assessment Report (EUリスク評価書) Henderson C, Pickering QH and Lemke AE The effect of some organic cyanides (nitriles) on fish. Proceedings of the 15th Industrial Waste Conference, Eng Bull Purdue Univ. XLV (2) 1961 2016/02/22
魚類 Oryzias latipes (Japanese medaka) LC50 >1000 mg/L 7 EU Risk Assessment Report (EUリスク評価書) Tonogai Y Ogawa S, Ito Y and Iwaida M Actual survey on TLm (median tolerance limit) values of environmental pollutants, especially on amines, nitriles, aromatic nitrogen compounds and artificial dyes J. Toxicol Sci, 7 1982 2016/02/22
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours >100 mg/L 7 EU Risk Assessment Report (EUリスク評価書) Ewell WS et al. Environ. Toxic. Chem 5 1986 2016/02/22
魚類 Cyprinus carpio (Carp) LC50 48 hours 730 mg/L 7 EU Risk Assessment Report (EUリスク評価書) Nishiuchi Y Toxicity of pesticides to some aquatics animals. II. Toxicity of several solvents to carp and daphnids. Seitai Kagaku, 4 1981 2016/02/22
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours 1640 mg/L 7 EU Risk Assessment Report (EUリスク評価書) Centre for Lake Superior Environmental studies 2016/02/22
魚類 Lepomis macrochirus (Bluegill) LC50 1850 mg/L 7 EU Risk Assessment Report (EUリスク評価書) Henderson C, Pickering QH and Lemke AE The effect of some organic cyanides (nitriles) on fish. Proceedings of the 15th Industrial Waste Conference, Eng Bull Purdue Univ. XLV (2) 1961 2016/02/22
魚類 Oryzias latipes (Japanese medaka) 48 hours 730 mg/L 7 EU Risk Assessment Report (EUリスク評価書) IUCLID 2016/02/22
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours 1000~1150 7 EU Risk Assessment Report (EUリスク評価書) Henderson C, Pickering QH and Lemke AE The effect of some organic cyanides (nitriles) on fish. Proceedings of the 15th Industrial Waste Conference, Eng Bull Purdue Univ. XLV (2) 1961 2016/02/22
魚類 Leuciscus idus (Orfe) LC50 48 hours 5850~7050 7 EU Risk Assessment Report (EUリスク評価書) Juhnke I and Ludemann D Results of the testing of 200 chemical compounds for acute toxicity for fish by the orfe test. Z. Wasser Abwasser Forsch 11 1978 2016/02/22
魚類 Leuciscus idus (Orfe) Mortality LC50 96 hours 5800 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Furusjö, E., Andersson, M., Rahmberg, M., Svenson, A. Estimating environmentally important properties of chemicals from the chemical structure 2003 2016/02/08
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 96 hours 1630 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Russom, C.L., Bradbury, S.P., Broderius, S.J., Drummond, R.A. and Hammermeister, D.E. PREDICTING MODES OF TOXIC ACTION FROM CHEMICAL STRUCTURE: ACUTE TOXICITY IN THE FATHEAD MINNOW (PIMEPHALES PROMELAS) 1997 2016/02/08