有害性クラス判定の根拠データ 79947

化学物質有害性情報データベース物質情報

CAS 登録番号 CAS RN^® ： 79947
官報公示整理番号　METI No. ： 6-353
物質名 test material ：２，２’－ビス（４’－ヒドロキシ－３’，５’－ジブロモフェニル）プロパン　／Tetrabromobisphenol A
水溶解度 water solubility ： 0.001002mg/L (推計値 estimated)
LogKow ： 7.2 (推計値 estimated)
備考 remarks ：

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【注意事項】
* 化学物質有害性情報データベース情報更新日が2019年9月以前はRead-acrossデータでも○としていないので、毒性値の取り扱いには注意が必要である。

生物種	学名	影響内容	エンドポイント	暴露期間(値)	暴露期間(単位)	毒性値	毒性値(単位)	Read-across *	GLP	設定濃度	実測濃度	情報源	情報源による信頼性評価	著者	タイトル	記載誌	発行年	情報更新日
藻類	Skeletonema costatum		TBBPA was toxic to S. costatum below the estimated saturation concentration (1.5 mg/litre)									12 ECHA Information on Registered Substances		Walsh and Alexander	A marine algal bioassay method: Results with pesticides and industrial wastes	Water Air Soil Pollut. 13		2021/03/02
藻類	Chlorella sp.		Chlorella sp. was not inhibited by as much as 50 % by 1.5 mg/L TBBPA									12 ECHA Information on Registered Substances		Walsh GE, Yoder MJ, McLaughlin LL & Lores EM	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotox. Environ. Safe 14		2021/03/02
藻類	Chlorella sp.								×	0.05 mL test material in nanograde acetone and 51 mL growth medium with algae		12 ECHA Information on Registered Substances	2	Walsh and Alexander	A marine algal bioassay method: Results with pesticides and industrial wastes	Water Air Soil Pollut. 13	1980
藻類	Thalassiosira pseudonana								×	0.05 mL test material in nanograde acetone and 51 mL growth medium with algae		12 ECHA Information on Registered Substances	2	Walsh GE, Yoder MJ, McLaughlin LL & Lores EM	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotox. Environ. Safe 14	1987
藻類	Skeletonema costatum								×	0.05 mL test material in nanograde acetone and 51 mL growth medium with algae		12 ECHA Information on Registered Substances	2	Walsh GE, Yoder MJ, McLaughlin LL & Lores EM	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotox. Environ. Safe 14	1987
藻類	Pseudokirchneriella subcapitata	Population	LOEC	3	days	9.2	μM					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise	Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays	Chemosphere85(1): 50-55	2011	2016/03/25
藻類	Pseudokirchneriella subcapitata	Population	LOEC	3	days	9.2	μM					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise	Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays	Chemosphere85(1): 50-55	2011	2016/03/25
藻類	Pseudokirchneriella subcapitata	Population	LOEC	3	days	9.2	μM					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise	Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays	Chemosphere85(1): 50-55	2011	2016/03/25
藻類	Pseudokirchneriella subcapitata	Population	LOEC	3	days	9.2	μM					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise	Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays	Chemosphere85(1): 50-55	2011	2016/03/25
藻類	Pseudokirchneriella subcapitata	Population	NOEC	3	days	4.8	μM					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise	Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays	Chemosphere85(1): 50-55	2011	2016/03/25
藻類	Pseudokirchneriella subcapitata	Population	NOEC	3	days	4.8	μM					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise	Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays	Chemosphere85(1): 50-55	2011	2016/03/25
藻類	Pseudokirchneriella subcapitata	Population	NOEC	3	days	4.8	μM					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise	Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays	Chemosphere85(1): 50-55	2011	2016/03/25
藻類	Pseudokirchneriella subcapitata	Population	NOEC	3	days	4.8	μM					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise	Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays	Chemosphere85(1): 50-55	2011	2016/03/25
藻類	Selenastrum capricornutum	成長曲線下面積	EbC50	72	hours	7.08	mg/L		○	対照区,　助剤対照区,　0.50, 1.05, 2.20, 4.60, 9.55, 20.0mg/l	0 hour : 0.59, 1.25, 2.54, 4.26, 9.02, 19.0mg/l　　　72 hour : 0.35, 0.77, 1.55, 2.77, 6.09, 13.3mg/l	1 日本環境省　生態リスク初期評価						2020/01/08
藻類	Skeletonema costatum	Growth rate	EC50	72	hours	0.89	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.	Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.	Environ. Safety, 14	1987	2020/01/07
藻類	Chlorella sp.	Growth rate	EC50	96	hours	>1.5	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.	Responses of marine unicellular algae to brominated organic compounds in six growth media.	Ecotox. Environ. Safety, 14	1987	2020/01/07
藻類	Chlorella sp.	Growth rate	EC50	96	hours	>1.5	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.	Responses of marine unicellular algae to brominated organic compounds in six growth media.	Ecotox. Environ. Safety, 14	1987	2020/01/07
藻類	Chlorella sp.	Growth rate	EC50	96	hours	>1.5	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.	Responses of marine unicellular algae to brominated organic compounds in six growth media.	Ecotox. Environ. Safety, 14	1987	2020/01/07
藻類	Chlorella sp.	Growth rate	EC50	96	hours	>1.5	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.	Responses of marine unicellular algae to brominated organic compounds in six growth media.	Ecotox. Environ. Safety, 14	1987	2020/01/07
藻類	Chlorella sp.	Growth rate	EC50	96	hours	>=1.5	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.	Responses of marine unicellular algae to brominated organic compounds in six growth media.	Ecotox. Environ. Safety, 14	1987	2020/01/07
藻類	Pseudokirchneriella subcapitata	成長曲線下面積	EbC50	72	hours	1.53	mg/L		○	対照区,　助剤対照区,　0.570, 1.00, 1.80, 3.20, 5.70mg/l	0.153, 0.268, 0.497, 0.919, 1.88mg/l	1 日本環境省　生態リスク初期評価						2020/01/10
藻類	Thalassiosira pseudonana	Growth rate	EC50	72	hours	0.83	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.	Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.	Environ. Safety, 14	1987	2020/01/07
藻類	Selenastrum capricornutum	成長速度	ErC50	72	hours	9.46	mg/L		○	対照区,　助剤対照区,　0.50, 1.05, 2.20, 4.60, 9.55, 20.0mg/l	0 hour : 0.59, 1.25, 2.54, 4.26, 9.02, 19.0mg/l　　　72 hour : 0.35, 0.77, 1.55, 2.77, 6.09, 13.3mg/l	1 日本環境省　生態リスク初期評価						2020/01/08
藻類	Chlorella sp.	Growth rate	EC50	96	hours	>1.5	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.	Responses of marine unicellular algae to brominated organic compounds in six growth media.	Ecotox. Environ. Safety, 14	1987	2020/01/07
藻類	Skeletonema costatum	Growth rate	EC50	72	hours	0.55	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.	Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.	Environ. Safety, 14	1987	2020/01/07
藻類	Skeletonema costatum	Growth rate	EC50	72	hours	0.09	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.	Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.	Environ. Safety, 14	1987	2020/01/07
藻類	Skeletonema costatum	Growth rate	EC50	72	hours	0.49	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.	Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.	Environ. Safety, 14	1987	2020/01/07
藻類	Skeletonema costatum	Growth rate	EC50	72	hours	0.14	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.	Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.	Environ. Safety, 14	1987	2020/01/07
藻類	Selenastrum capricornutum	Cell density	EC50	96	hours	>5600	μg/L		○	340, 760, 1500, 3000, 5600µg TBBPA/l		14 BUA Report		Great Lakes Chemical Corporation	Toxicity of tetrabromobisphenol A to the freshwater green alga Selenastrum capricornutum. Springborn Laboratories, Report No: 88-10-2828		1988	2020/01/22
藻類	Skeletonema costatum		EC50	72	hours	0.09～0.89	mg/L					4 OECD SIDS (HPVC)						2020/01/17
藻類	Pseudokirchneriella subcapitata		EC50	72	hours	>5.6	mg/L					4 OECD SIDS (HPVC)						2020/01/17
藻類	Pseudokirchneriella subcapitata	成長速度	ErC50	72	hours	>1.88	mg/L		○	対照区,　助剤対照区,　0.570, 1.00, 1.80, 3.20, 5.70mg/l	0.153, 0.268, 0.497, 0.919, 1.88mg/l	1 日本環境省　生態リスク初期評価						2020/01/10
藻類	Thalassiosira pseudonana	Growth rate	EC50	72	hours	0.21	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.	Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.	Environ. Safety, 14	1987	2020/01/07
藻類	Chlorella sp.		EC50	96	hours	>1500	μg/L					14 BUA Report		Walsh G, Yoder M, McLaughlin L, Lores E	Responses of marine unicellular algae to brominated organic compounds in six growth media.	Ecotox Environ Saf 14	1987	2020/01/21
藻類	Thalassiosira pseudonana		EC50	72	hours	130～1000	μg/L					14 BUA Report		Walsh G, Yoder M, McLaughlin L, Lores E	Responses of marine unicellular algae to brominated organic compounds in six growth media.	Ecotox Environ Saf 14	1987	2020/01/21
藻類	Skeletonema costatum		EC50	72	hours	90～890	μg/L					14 BUA Report		Walsh G, Yoder M, McLaughlin L, Lores E	Responses of marine unicellular algae to brominated organic compounds in six growth media.	Ecotox Environ Saf 14	1987	2020/01/21
藻類	Thalassiosira pseudonana	Growth rate	EC50	72	hours	0.31	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.	Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.	Environ. Safety, 14	1987	2020/01/07
藻類	Thalassiosira pseudonana	Growth rate	EC50	72	hours	0.13	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.	Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.	Environ. Safety, 14	1987	2020/01/07
藻類	Pseudokirchneriella subcapitata	収量	EyC50	72	hours	1.57	mg/L		○	対照区,　助剤対照区,　0.570, 1.00, 1.80, 3.20, 5.70mg/l	0.153, 0.268, 0.497, 0.919, 1.88mg/l	1 日本環境省　生態リスク初期評価						2020/01/10
藻類	Thalassiosira pseudonana	Growth rate	EC50	72	hours	1	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.	Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.	Environ. Safety, 14	1987	2020/01/07
藻類	Thalassiosira pseudonana	Growth rate	EC50	72	hours	0.17	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.	Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.	Environ. Safety, 14	1987	2020/01/07
藻類	Selenastrum capricornutum	Biomass	EC50	3	days	7080	μg/L					6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）	a	環境庁	平成11年度　生態影響試験実施事業報告		2000	2020/02/14
藻類	Pseudokirchneriella subcapitata	Cell density (biomass)	EC50	96	hours	>5.6	mg/L				0.34, 0.76, 1.5, 3.0, 5.6mg/l, control, solvent control	7 EU Risk Assessment Report (EUリスク評価書）	2	Springborn Life Sciences	Toxicity of tetrabromobisphenol A to the freshwater green alga Selenastrum capricornutum.	Report No 88-10-2828. Springborn Life Sciences, Inc., Wareham, Massachusetts	1988	2019/12/27
藻類	Pseudokirchneriella subcapitata	Growth rate	ErC50	72	hours	9.48	mg/L			0, 0.50, 1.05, 2.20, 4.60, 9.55, 20.0mg/l	0, 0.45, 0.98, 1.98, 3.44, 7.41, 15.9mg/l 設定値の93～119％（0h)、60～73％（72h)	18 既存化学物質安全性(ハザード)評価シート		環境省	既存化学物質審査シート（三監No.10）			2020/01/08
藻類	Pseudokirchneriella subcapitata	Cell density (biomass)	EC50	72	hours	>5.6	mg/L				0.34, 0.76, 1.5, 3.0, 5.6mg/l, control, solvent control	7 EU Risk Assessment Report (EUリスク評価書）	2	Springborn Life Sciences	Toxicity of tetrabromobisphenol A to the freshwater green alga Selenastrum capricornutum.	Report No 88-10-2828. Springborn Life Sciences, Inc., Wareham, Massachusetts	1988	2019/12/27
藻類	Thalassiosira pseudonana	PopulationPopulation change (change in N/change in time)	EC50 EC50	72	hours	140	μg/L [Formulation]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotoxicol. Environ. Saf.14	1987
藻類	Skeletonema costatum	PopulationPopulation change (change in N/change in time)	EC50 EC50	72	hours	560	μg/L [Formulation]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotoxicol. Environ. Saf.14	1987
藻類	Thalassiosira pseudonana	PopulationPopulation change (change in N/change in time)	EC50 EC50	72	hours	820	μg/L [Formulation]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotoxicol. Environ. Saf.14	1987
藻類	Thalassiosira pseudonana	PopulationPopulation change (change in N/change in time)	EC50 EC50	72	hours	1000	μg/L [Formulation]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotoxicol. Environ. Saf.14	1987
藻類	Thalassiosira pseudonana	PopulationPopulation change (change in N/change in time)	EC50 EC50	72	hours	350	μg/L [Formulation]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotoxicol. Environ. Saf.14	1987
藻類	Skeletonema costatum	PopulationPopulation change (change in N/change in time)	EC50 EC50	72	hours	550	μg/L [Formulation]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotoxicol. Environ. Saf.14	1987
藻類	Skeletonema costatum	PopulationPopulation change (change in N/change in time)	EC50 EC50	72	hours	410	μg/L [Formulation]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotoxicol. Environ. Saf.14	1987
藻類	Thalassiosira pseudonana	PopulationPopulation change (change in N/change in time)	EC50 EC50	72	hours	220	μg/L [Formulation]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotoxicol. Environ. Saf.14	1987
藻類	Skeletonema costatum	PopulationPopulation change (change in N/change in time)	EC50 EC50	72	hours	140	μg/L [Formulation]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotoxicol. Environ. Saf.14	1987
藻類	Thalassiosira pseudonana	PopulationPopulation change (change in N/change in time)	EC50 EC50	72	hours	110	μg/L [Formulation]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotoxicol. Environ. Saf.14	1987
藻類	Thalassiosira pseudonana	PopulationPopulation change (change in N/change in time)	EC50 EC50	72	hours	260	μg/L [Formulation]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotoxicol. Environ. Saf.14	1987
藻類	Thalassiosira pseudonana	PopulationPopulation change (change in N/change in time)	EC50 EC50	72	hours	170	μg/L [Formulation]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotoxicol. Environ. Saf.14	1987
藻類	Skeletonema costatum	PopulationPopulation change (change in N/change in time)	EC50 EC50	72	hours	90	μg/L [Formulation]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotoxicol. Environ. Saf.14	1987
藻類	Thalassiosira pseudonana	PopulationPopulation change (change in N/change in time)	EC50 EC50	72	hours	190	μg/L [Formulation]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotoxicol. Environ. Saf.14	1987
藻類	Skeletonema costatum	PopulationPopulation change (change in N/change in time)	EC50 EC50	72	hours	640	μg/L [Formulation]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotoxicol. Environ. Saf.14	1987
藻類	Skeletonema costatum	PopulationPopulation change (change in N/change in time)	EC50 EC50	72	hours	1140	μg/L [Formulation]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotoxicol. Environ. Saf.14	1987
藻類	Skeletonema costatum	PopulationPopulation change (change in N/change in time)	EC50 EC50	72	hours	540	μg/L [Formulation]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotoxicol. Environ. Saf.14	1987
藻類	Thalassiosira pseudonana	PopulationPopulation change (change in N/change in time)	EC50 EC50	72	hours	160	μg/L [Formulation]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotoxicol. Environ. Saf.14	1987
藻類	Thalassiosira pseudonana	PopulationPopulation change (change in N/change in time)	EC50 EC50	72	hours	840	μg/L [Formulation]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotoxicol. Environ. Saf.14	1987
藻類	Skeletonema costatum	PopulationPopulation change (change in N/change in time)	EC50 EC50	72	hours	80	μg/L [Formulation]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media	Ecotoxicol. Environ. Saf.14	1987
藻類	Pseudokirchneriella subcapitata		EC50	72	hours	>1.9	mg/L					1 日本環境省　生態リスク初期評価		環境省	（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）			2016/11/09
藻類	Pseudokirchneriella subcapitata		EC50	72	hours	9.5	mg/L					1 日本環境省　生態リスク初期評価		環境省	（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）			2016/11/09
藻類	Pseudokirchneriella subcapitata		EC50	72	hours	7.1	mg/L					1 日本環境省　生態リスク初期評価		環境省	（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）			2016/11/09
藻類	Pseudokirchneriella subcapitata		EC50	72	hours	1.5	mg/L					1 日本環境省　生態リスク初期評価		環境省	（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）			2016/11/09
藻類	Pseudokirchneriella subcapitata	生長阻害	EbC50	72	hours	1.53	mg/L					11 Japan チャレンジプログラム		-	2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験	A050386		2016/03/08
藻類	Selenastrum capricornutum	生長阻害	EbC50	72	hours	3.1	mg/L					11 Japan チャレンジプログラム		-	2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験	EAI95005		2016/03/08
藻類	Pseudokirchneriella subcapitata	biomass	EC50	96	hours	>5.6	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Springborn Life Sciences	Toxicity of tetrabromobisphenol A to the freshwater green alga Selenastrum capricornutum.	Report No 88-10-2828. Springborn Life Sciences, Inc., Wareham, Massachusetts.	1988	2016/03/04
藻類	Selenastrum capricornutum	生長阻害　24-48h	ErC50	72	hours	5.8	mg/L					11 Japan チャレンジプログラム		-	2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験	EAI95005		2016/03/08
藻類	Pseudokirchneriella subcapitata	生長阻害	EyC50	72	hours	1.57	mg/L					11 Japan チャレンジプログラム		-	2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験	A050386		2016/03/08
藻類	Pseudokirchneriella subcapitata	生長阻害	ErC50	72	hours	>1.88	mg/L					11 Japan チャレンジプログラム		-	2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験	A050386		2016/03/08
藻類	Selenastrum capricornutum	生長阻害　24-72h	ErC50	72	hours	13.6	mg/L					11 Japan チャレンジプログラム		-	4，4’一イソプロピリデンビス（2，6一ジブロモフェノール）の藻類（Selenastrum capricornutum)に対する生長阻害試験	9B434G		2016/03/08
藻類	Pseudokirchneriella subcapitata	biomass	EC50	72	hours	>5.6	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Springborn Life Sciences	Toxicity of tetrabromobisphenol A to the freshwater green alga Selenastrum capricornutum.	Report No 88-10-2828. Springborn Life Sciences, Inc., Wareham, Massachusetts.	1988	2016/03/04
藻類	Chlorella sp.	population growth		4	days	1500	μg/L					6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）	a	Walsh,G.E., M.J.Yoder, L.L.McLaughlin, and E.M.Lores	Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media.	Ecotoxicol. Environ. Saf.	1987	2016/03/04
藻類	Selenastrum capricornutum	Biomass	EC50	3	days	7080	μg/L					6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）	a	環境庁	平成 11 年度　生態影響試験実施事業報告		2000	2016/03/05
藻類	Selenastrum capricornutum	生長阻害　24-48h	ErC50	72	hours	13.2	mg/L					11 Japan チャレンジプログラム		-	4，4’一イソプロピリデンビス（2，6一ジブロモフェノール）の藻類（Selenastrum capricornutum)に対する生長阻害試験	9B434G		2016/03/08
藻類	Selenastrum capricornutum	生長阻害	EbC50	72	hours	7.08	mg/L					11 Japan チャレンジプログラム		-	4，4’一イソプロピリデンビス（2，6一ジブロモフェノール）の藻類（Selenastrum capricornutum)に対する生長阻害試験	9B434G		2016/03/08
藻類	Selenastrum capricornutum	生長阻害　24-72h	ErC50	72	hours	4.3	mg/L					11 Japan チャレンジプログラム		-	2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験	EAI95005		2016/03/08
藻類	Pseudokirchneriella subcapitata		EC50	72	hours	>5.6	mg/L					4 OECD SIDS (HPVC)						2016/02/19
藻類	Pseudokirchneriella subcapitata		EC50	72	hours	>5.6	mg/L					4 OECD SIDS (HPVC)						2016/02/19
藻類	Skeletonema costatum	Population size reduction	EC50	3	days	80	μg/L					6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）	a	-	2-（ジメチルアミノ）エチルメタクリレートのオオミジンコ（Daphnia magna)に対する急性遊泳阻害試験	N01997-生16		2020/02/14
藻類	Chlorella sp.	Population growth		4	days	1500	μg/L					6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）	a	-	2-（ジメチルアミノ）エチルメタクリレートのオオミジンコ（Daphnia magna)に対する繁殖阻害試験	N01997-生17		2020/02/14
藻類	Scenedesmus obliquus		EC50	10	days	>0.4	mg/L					19 その他		Peng FQ, Ying GG, Yang B, Liu YS, Lai HJ, Zhou GJ, Chen J and Zhao JL	Biotransformation of the flame retardant tetrabromobisphenol‐A (TBBPA) by freshwater microalgae	Environmental Toxicology and Chemistry, 33		2021/05/14
藻類	Scenedesmus acuminatus		EC50	10	days	>0.4	mg/L					19 その他		Peng FQ, Ying GG, Yang B, Liu YS, Lai HJ, Zhou GJ, Chen J and Zhao JL	Biotransformation of the flame retardant tetrabromobisphenol‐A (TBBPA) by freshwater microalgae	Environmental Toxicology and Chemistry, 33		2021/05/14
藻類	Pseudokirchneriella subcapitata		EC50	10	days	>0.4	mg/L					19 その他		Peng FQ, Ying GG, Yang B, Liu YS, Lai HJ, Zhou GJ, Chen J and Zhao JL	Biotransformation of the flame retardant tetrabromobisphenol‐A (TBBPA) by freshwater microalgae	Environmental Toxicology and Chemistry, 33		2021/04/14
藻類	Scenedesmus quadricauda	cell number	EC50	96	hours	1.202	mg/L			0 mg/L / 0 mg/L / 0.4 mg/L / 0.56 mg/L / 0.784 mg/		16 ECOTOX		Yang,S.W., Z.G. Yan, F.F. Xu, S.R. Wang, and F.C. Wu	Development of Freshwater Aquatic Life Criteria for Tetrabromobisphenol A in China	Environ. Pollut.169		2020/11/12
藻類	Pseudokirchneriella subcapitata	Chlorophyll	EC50	72	hours	14.2	μmol/L			0 umol/L / 1.8 umol/L / 4.8 umol/L / 9.2 umol/L /		16 ECOTOX		Debenest,T., F. Gagne, A.N. Petit, M. Kohli, P. Eullafroy, and C. Blaise	Monitoring of a Flame Retardant (Tetrabromobisphenol A) Toxicity on Different Microalgae Assessed by Flow Cytometry	J. Environ. Monit.12(10)		2020/11/12
藻類	Chlorella pyrenoidosa		EC50	10	days	>0.4	mg/L					19 その他		Peng FQ, Ying GG, Yang B, Liu YS, Lai HJ, Zhou GJ, Chen J and Zhao JL	Biotransformation of the flame retardant tetrabromobisphenol‐A (TBBPA) by freshwater microalgae	Environmental Toxicology and Chemistry, 33		2021/04/14
藻類	Scenedesmus quadricauda		EC50	10	days	>0.4	mg/L					19 その他		Peng FQ, Ying GG, Yang B, Liu YS, Lai HJ, Zhou GJ, Chen J and Zhao JL	Biotransformation of the flame retardant tetrabromobisphenol‐A (TBBPA) by freshwater microalgae	Environmental Toxicology and Chemistry, 33		2021/05/14
藻類	Selenastrum capricornutum	Growth	EC50	96	hours	>5.6	mg/L	×			0.34-5.6 mg/L	19 その他		IPCS	Environmental health criteria 172, Tetrabromobisphenol A and derivatives	Geneva, World Health Organization		2021/04/13
藻類	Chlorella sp.	Growth	EC50	96	hours	>1500	μg/L	×				19 その他		IPCS	Environmental health criteria 172, Tetrabromobisphenol A and derivatives	Geneva, World Health Organization		2021/04/13
藻類	Thalassiosira pseudonana		EC50	72	hours	130～1000	μg/L	×				19 その他		IPCS	Environmental health criteria 172, Tetrabromobisphenol A and derivatives	Geneva, World Health Organization		2021/04/13
藻類	Skeletonema costatum		EC50	72	hours	90～890	μg/L	×				19 その他		IPCS	Environmental health criteria 172, Tetrabromobisphenol A and derivatives	Geneva, World Health Organization		2021/04/13
藻類	Pseudokirchneriella subcapitata	成長曲線下面積	NOEbC	72	hours	0.268	mg/L		○	対照区,　助剤対照区,　0.570, 1.00, 1.80, 3.20, 5.70mg/l	0.153, 0.268, 0.497, 0.919, 1.88mg/l	1 日本環境省　生態リスク初期評価						2020/01/10
藻類	Pseudokirchneriella subcapitata	Growth rate	NOEC	72	hours	1.98	mg/L			0, 0.50, 1.05, 2.20, 4.60, 9.55, 20.0mg/l	0, 0.45, 0.98, 1.98, 3.44, 7.41, 15.9mg/l 設定値の93～119％（0h)、60～73％（72h)	18 既存化学物質安全性(ハザード)評価シート		環境省	既存化学物質審査シート（三監No.10）			2020/01/08
藻類	Selenastrum capricornutum	成長曲線下面積	NOEbC	72	hours	4.6	mg/L		○	対照区,　助剤対照区,　0.50, 1.05, 2.20, 4.60, 9.55, 20.0mg/l	0 hour : 0.59, 1.25, 2.54, 4.26, 9.02, 19.0mg/l　　　72 hour : 0.35, 0.77, 1.55, 2.77, 6.09, 13.3mg/l	1 日本環境省　生態リスク初期評価						2020/01/08
藻類	Selenastrum capricornutum	成長速度	NOEC	72	hours	3.44	mg/L		○	対照区,　助剤対照区,　0.50, 1.05, 2.20, 4.60, 9.55, 20.0mg/l	0 hour : 0.59, 1.25, 2.54, 4.26, 9.02, 19.0mg/l　　　72 hour : 0.35, 0.77, 1.55, 2.77, 6.09, 13.3mg/l	1 日本環境省　生態リスク初期評価						2020/01/08
藻類	Pseudokirchneriella subcapitata	成長速度	NOErC	72	hours	0.497	mg/L		○	対照区,　助剤対照区,　0.570, 1.00, 1.80, 3.20, 5.70mg/l	0.153, 0.268, 0.497, 0.919, 1.88mg/l	1 日本環境省　生態リスク初期評価						2020/01/10
藻類	Pseudokirchneriella subcapitata	収量	NOEyC	72	hours	0.268	mg/L		○	対照区,　助剤対照区,　0.570, 1.00, 1.80, 3.20, 5.70mg/l	0.153, 0.268, 0.497, 0.919, 1.88mg/l	1 日本環境省　生態リスク初期評価						2020/01/10
藻類	Pseudokirchneriella subcapitata		NOEC	72	hours	>=5.6	mg/L					4 OECD SIDS (HPVC)						2020/01/17
藻類	Selenastrum capricornutum	Biomass	NOEC	3	days	4600	μg/L					6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）	a	環境庁	平成11年度　生態影響試験実施事業報告		2000	2020/02/14
藻類	Pseudokirchneriella subcapitata	Cell density (biomass)	NOEC	72	hours	>=5.6	mg/L				0.34, 0.76, 1.5, 3.0, 5.6mg/l, control, solvent control	7 EU Risk Assessment Report (EUリスク評価書）	2	Springborn Life Sciences	Toxicity of tetrabromobisphenol A to the freshwater green alga Selenastrum capricornutum.	Report No 88-10-2828. Springborn Life Sciences, Inc., Wareham, Massachusetts	1988	2019/12/27
藻類	Pseudokirchneriella subcapitata	Cell density (biomass)	NOEC	96	hours	>=5.6	mg/L				0.34, 0.76, 1.5, 3.0, 5.6mg/l, control, solvent control	7 EU Risk Assessment Report (EUリスク評価書）	2	Springborn Life Sciences	Toxicity of tetrabromobisphenol A to the freshwater green alga Selenastrum capricornutum.	Report No 88-10-2828. Springborn Life Sciences, Inc., Wareham, Massachusetts	1988	2019/12/27
藻類	Pseudokirchneriella subcapitata	PopulationAbundance	NOEC NOEC	72	hours	4.8	μM [Active ingredient]				0 uM / 1.8 uM / 4.8 uM / 9.2 uM / 12.9 uM / 16.5 uM	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise	Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays	Chemosphere85(1)	2011
藻類	Pseudokirchneriella subcapitata	PopulationAbundance	LOEC LOEC	72	hours	9.2	μM [Active ingredient]				0 uM / 1.8 uM / 4.8 uM / 9.2 uM / 12.9 uM / 16.5 uM	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise	Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays	Chemosphere85(1)	2011
藻類	Pseudokirchneriella subcapitata	PopulationPopulation growth rate	LOEC LOEC	72	hours	9.2	μM [Active ingredient]				0 uM / 1.8 uM / 4.8 uM / 9.2 uM / 12.9 uM / 16.5 uM	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise	Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays	Chemosphere85(1)	2011
藻類	Pseudokirchneriella subcapitata	PopulationAbundance	LOEC LOEC	72	hours	9.2	μM [Active ingredient]				0 uM / 1.8 uM / 4.8 uM / 9.2 uM / 12.9 uM / 16.5 uM	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise	Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays	Chemosphere85(1)	2011
藻類	Pseudokirchneriella subcapitata	PopulationPopulation growth rate	LOEC LOEC	72	hours	9.2	μM [Active ingredient]				0 uM / 1.8 uM / 4.8 uM / 9.2 uM / 12.9 uM / 16.5 uM	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise	Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays	Chemosphere85(1)	2011
藻類	Pseudokirchneriella subcapitata	PopulationPopulation growth rate	NOEC NOEC	72	hours	4.8	μM [Active ingredient]				0 uM / 1.8 uM / 4.8 uM / 9.2 uM / 12.9 uM / 16.5 uM	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise	Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays	Chemosphere85(1)	2011
藻類	Pseudokirchneriella subcapitata	PopulationPopulation growth rate	NOEC NOEC	72	hours	4.8	μM [Active ingredient]				0 uM / 1.8 uM / 4.8 uM / 9.2 uM / 12.9 uM / 16.5 uM	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise	Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays	Chemosphere85(1)	2011
藻類	Pseudokirchneriella subcapitata	PopulationAbundance	NOEC NOEC	72	hours	4.8	μM [Active ingredient]				0 uM / 1.8 uM / 4.8 uM / 9.2 uM / 12.9 uM / 16.5 uM	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise	Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays	Chemosphere85(1)	2011
藻類	Pseudokirchneriella subcapitata	cell number	NOEC	96	hours	5.6	mg/L		○	0.60, 1.2, 2.4, 4.8, 9.6 mg/L TBBPA	0.34, 0.76, 1.5, 3.0, 5.6 mg/L TBBPA	12 ECHA Information on Registered Substances	1		study report		1988
藻類	Pseudokirchneriella subcapitata		NOEC	72	hours	0.5	mg/L					1 日本環境省　生態リスク初期評価		環境省	（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）			2016/11/09
藻類	Pseudokirchneriella subcapitata		NOEC	72	hours	4.6	mg/L					1 日本環境省　生態リスク初期評価		環境省	（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）			2016/11/09
藻類	Pseudokirchneriella subcapitata		NOEC	72	hours	0.27	mg/L					1 日本環境省　生態リスク初期評価		環境省	（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）			2016/11/09
藻類	Pseudokirchneriella subcapitata		NOEC	72	hours	2	mg/L					1 日本環境省　生態リスク初期評価		環境省	（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）			2016/11/09
藻類	Selenastrum capricornutum	生長阻害　24-72h	NOErC	72	hours	1.8	mg/L					11 Japan チャレンジプログラム		-	2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験	EAI95005		2016/03/08
藻類	Pseudokirchneriella subcapitata	biomass	NOEC	96	hours	>=5.6	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Springborn Life Sciences	Toxicity of tetrabromobisphenol A to the freshwater green alga Selenastrum capricornutum.	Report No 88-10-2828. Springborn Life Sciences, Inc., Wareham, Massachusetts.	1988	2016/03/04
藻類	Pseudokirchneriella subcapitata	biomass	NOEC	72	hours	>=5.6	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Springborn Life Sciences	Toxicity of tetrabromobisphenol A to the freshwater green alga Selenastrum capricornutum.	Report No 88-10-2828. Springborn Life Sciences, Inc., Wareham, Massachusetts.	1988	2016/03/04
藻類	Selenastrum capricornutum	生長阻害　24-72h	NOErC	72	hours	4.6	mg/L					11 Japan チャレンジプログラム		-	4，4’一イソプロピリデンビス（2，6一ジブロモフェノール）の藻類（Selenastrum capricornutum)に対する生長阻害試験	9B434G		2016/03/08
藻類	Pseudokirchneriella subcapitata	生長阻害	NOErC	72	hours	0.497	mg/L					11 Japan チャレンジプログラム		-	2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験	A050386		2016/03/08
藻類	Selenastrum capricornutum	cell density	NOEC	96	hours	0.35	mg/L					10 EHC (Environmental Health Criteria)		Giddings JM	Toxicity of tetrabromobisphenol A to the freshwater green alga Selenastrum capricornutum.	Wareham, Massachusetts, Springborn Life Sciences, Inc. (Report No. 88-10-2828 submitted to WHO by the Brominated Flame Retardant Industry Panel).	1988	2016/03/04
藻類	Pseudokirchneriella subcapitata	生長阻害	NOEbC	72	hours	0.268	mg/L					11 Japan チャレンジプログラム		-	2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験	A050386		2016/03/08
藻類	Selenastrum capricornutum	Biomass	NOEC	3	days	4600	μg/L					6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）	a	環境庁	平成 11 年度　生態影響試験実施事業報告		2000	2016/03/04
藻類	Pseudokirchneriella subcapitata	生長阻害	NOEyC	72	hours	0.268	mg/L					11 Japan チャレンジプログラム		-	2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験	A050386		2016/03/08
藻類	Selenastrum capricornutum	生長阻害	NOEbC	72	hours	4.6	mg/L					11 Japan チャレンジプログラム		-	4，4’一イソプロピリデンビス（2，6一ジブロモフェノール）の藻類（Selenastrum capricornutum)に対する生長阻害試験	9B434G		2016/03/08
藻類	Selenastrum capricornutum	生長阻害　24-48h	NOErC	72	hours	3.2	mg/L					11 Japan チャレンジプログラム		-	2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験	EAI95005		2016/03/08
藻類	Selenastrum capricornutum	生長阻害　24-48h	NOErC	72	hours	9.55	mg/L					11 Japan チャレンジプログラム		-	4，4’一イソプロピリデンビス（2，6一ジブロモフェノール）の藻類（Selenastrum capricornutum)に対する生長阻害試験	9B434G		2016/03/08
藻類	Selenastrum capricornutum	生長阻害	NOEbC	72	hours	1	mg/L					11 Japan チャレンジプログラム		-	2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験	EAI95005		2016/03/08
藻類	Chlorella pyrenoidosa	cell number	NOEC	72	hours	3.7	μM			0 uM / 0.3 uM / 0.9 uM / 1.8 uM / 3.7 uM / 9.2 uM		16 ECOTOX		Peng,F.Q., G.G. Ying, B. Yang, Y.S. Liu, H.J. Lai, G.J. Zhou, J. Chen, and J.L. Zhao	Biotransformation of the Flame Retardant Tetrabromobisphenol-A (TBBPA) by Freshwater Microalgae	Environ. Toxicol. Chem.33(8)		2020/11/12
藻類	Scenedesmus acutus var. acutus	cell number	LOEC	24	hours	9.2	μM			0 uM / 0.3 uM / 0.9 uM / 1.8 uM / 3.7 uM / 9.2 uM		16 ECOTOX		Peng,F.Q., G.G. Ying, B. Yang, Y.S. Liu, H.J. Lai, G.J. Zhou, J. Chen, and J.L. Zhao	Biotransformation of the Flame Retardant Tetrabromobisphenol-A (TBBPA) by Freshwater Microalgae	Environ. Toxicol. Chem.33(8)		2020/11/12
藻類	Selenastrum capricornutum	Growth	NOEC	96	hours	>=5.6	mg/L	×			0.34-5.6 mg/L	19 その他		IPCS	Environmental health criteria 172, Tetrabromobisphenol A and derivatives	Geneva, World Health Organization		2021/04/13
藻類	Scenedesmus acutus var. acutus	cell number	NOEC	72	hours	3.7	μM			0 uM / 0.3 uM / 0.9 uM / 1.8 uM / 3.7 uM / 9.2 uM		16 ECOTOX		Peng,F.Q., G.G. Ying, B. Yang, Y.S. Liu, H.J. Lai, G.J. Zhou, J. Chen, and J.L. Zhao	Biotransformation of the Flame Retardant Tetrabromobisphenol-A (TBBPA) by Freshwater Microalgae	Environ. Toxicol. Chem.33(8)		2020/11/12
藻類	Chlorella pyrenoidosa	cell number	NOEC	24	hours	3.7	μM			0 uM / 0.3 uM / 0.9 uM / 1.8 uM / 3.7 uM / 9.2 uM		16 ECOTOX		Peng,F.Q., G.G. Ying, B. Yang, Y.S. Liu, H.J. Lai, G.J. Zhou, J. Chen, and J.L. Zhao	Biotransformation of the Flame Retardant Tetrabromobisphenol-A (TBBPA) by Freshwater Microalgae	Environ. Toxicol. Chem.33(8)		2020/11/12
藻類	Chlorella pyrenoidosa	cell number	LOEC	24	hours	9.2	μM			0 uM / 0.3 uM / 0.9 uM / 1.8 uM / 3.7 uM / 9.2 uM		16 ECOTOX		Peng,F.Q., G.G. Ying, B. Yang, Y.S. Liu, H.J. Lai, G.J. Zhou, J. Chen, and J.L. Zhao	Biotransformation of the Flame Retardant Tetrabromobisphenol-A (TBBPA) by Freshwater Microalgae	Environ. Toxicol. Chem.33(8)		2020/11/12
藻類	Chlorella pyrenoidosa	cell number	LOEC	72	hours	9.2	μM			0 uM / 0.3 uM / 0.9 uM / 1.8 uM / 3.7 uM / 9.2 uM		16 ECOTOX		Peng,F.Q., G.G. Ying, B. Yang, Y.S. Liu, H.J. Lai, G.J. Zhou, J. Chen, and J.L. Zhao	Biotransformation of the Flame Retardant Tetrabromobisphenol-A (TBBPA) by Freshwater Microalgae	Environ. Toxicol. Chem.33(8)		2020/11/12
藻類	Scenedesmus acutus var. acutus	cell number	LOEC	72	hours	9.2	μM			0 uM / 0.3 uM / 0.9 uM / 1.8 uM / 3.7 uM / 9.2 uM		16 ECOTOX		Peng,F.Q., G.G. Ying, B. Yang, Y.S. Liu, H.J. Lai, G.J. Zhou, J. Chen, and J.L. Zhao	Biotransformation of the Flame Retardant Tetrabromobisphenol-A (TBBPA) by Freshwater Microalgae	Environ. Toxicol. Chem.33(8)		2020/11/12
藻類	Scenedesmus acutus var. acutus	cell number	NOEC	24	hours	3.7	μM			0 uM / 0.3 uM / 0.9 uM / 1.8 uM / 3.7 uM / 9.2 uM		16 ECOTOX		Peng,F.Q., G.G. Ying, B. Yang, Y.S. Liu, H.J. Lai, G.J. Zhou, J. Chen, and J.L. Zhao	Biotransformation of the Flame Retardant Tetrabromobisphenol-A (TBBPA) by Freshwater Microalgae	Environ. Toxicol. Chem.33(8)		2020/11/12
甲殻類	Acartia tonsa	Population//Sex ratio	LOEC	10	days	200	μg/L			0 ug/L / 0 ug/L / 1.3 ug/L / 25 ug/L / 50 ug/L / 1		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Acartia tonsa	Population//Sex ratio	EC50	10	days	158	μg/L			0 ug/L / 0 ug/L / 1.3 ug/L / 25 ug/L / 50 ug/L / 1		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Acartia tonsa	Development//Developmental changes, general	EC20		hours	3.3	μg/L			0 ug/L / 0 ug/L / 11.5 ug/L / 23 ug/L / 47 ug/L /		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Acartia tonsa	Development//Developmental changes, general	EC10		hours	1.4	μg/L			0 ug/L / 0 ug/L / 11.5 ug/L / 23 ug/L / 47 ug/L /		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Acartia tonsa	Growth(Length)	EC10	10	days	180	μg/L			0 ug/L / 0 ug/L / 1.3 ug/L / 25 ug/L / 50 ug/L / 1		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Acartia tonsa	Development//Developmental changes, general	EC50		hours	18	μg/L			0 ug/L / 0 ug/L / 11.5 ug/L / 23 ug/L / 47 ug/L /		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Acartia tonsa	Population//Sex ratio	EC20	10	days	113	μg/L			0 ug/L / 0 ug/L / 1.3 ug/L / 25 ug/L / 50 ug/L / 1		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Acartia tonsa	Population//Sex ratio	EC10	10	days	96	μg/L			0 ug/L / 0 ug/L / 1.3 ug/L / 25 ug/L / 50 ug/L / 1		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Daphnia magna	Reproduction	NOEC	16	days	1.3	mg/L			0 mg/L / 0.31 mg/L / 0.63 mg/L / 1.3 mg/L / 2.5 mg		16 ECOTOX		Great Lakes Chemical Corp.	The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989	EPA/OTS 40-8998117		2020/11/12
甲殻類	Acartia tonsa	Population//Sex ratio	NOEC	10	days	100	μg/L			0 ug/L / 0 ug/L / 1.3 ug/L / 25 ug/L / 50 ug/L / 1		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Daphnia magna	Reproduction	LOEC	16	days	2.5	mg/L			0 mg/L / 0.31 mg/L / 0.63 mg/L / 1.3 mg/L / 2.5 mg		16 ECOTOX		Great Lakes Chemical Corp.	The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989	EPA/OTS 40-8998117		2020/11/12
甲殻類	Mytilus edulis	growth	LOEC	70	days	32	μg/L		○	19, 38, 75, 150, 300 µg/L	17, 32, 62, 126, 226 µg/L	12 ECHA Information on Registered Substances	1		study report		2005
甲殻類	Crassostrea virginica	other: shell deposition	EC50	96	hours	98	μg/L		○	19, 32, 54, 90, 150 µg a.i./L	Measured (mean): 18 (3.9), 32 (5.4), 51 (11), 87 (18), 150 (22) µg a.i./L	12 ECHA Information on Registered Substances	1		study report		1989
甲殻類	Mytilus edulis	growth	LOEC	14	days	126	μg/L		○	19, 38, 75, 150, 300 µg/L	17, 32, 62, 126, 226 µg/L	12 ECHA Information on Registered Substances	1		study report		2005
甲殻類	Mytilus edulis	growth	LOEC	42	days	62	μg/L		○	19, 38, 75, 150, 300 µg/L	17, 32, 62, 126, 226 µg/L	12 ECHA Information on Registered Substances	1		study report		2005
甲殻類	Mytilus edulis	growth	NOEC	14	days	62	μg/L		○	19, 38, 75, 150, 300 µg/L	17, 32, 62, 126, 226 µg/L	12 ECHA Information on Registered Substances	1		study report		2005
甲殻類	Crassostrea virginica	other: shell deposition	NOEC	96	hours	<18	μg/L		○	19, 32, 54, 90, 150 µg a.i./L	Measured (mean): 18 (3.9), 32 (5.4), 51 (11), 87 (18), 150 (22) µg a.i./L	12 ECHA Information on Registered Substances	1		study report		1989
甲殻類	Mytilus edulis	growth	NOEC	42	days	32	μg/L		○	19, 38, 75, 150, 300 µg/L	17, 32, 62, 126, 226 µg/L	12 ECHA Information on Registered Substances	1		study report		2005
甲殻類	Daphnia magna	No Group Code	EC50	2	days	>0.9～<1.2						16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim	Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms	Water Res.27(2): 199-204	1993	2016/03/25
甲殻類	Daphnia magna	No Group Code	EC50	2	days	>0.9～<1.2						16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim	Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms	Water Res.27(2): 199-204	1993	2016/03/25
甲殻類	Daphnia magna	No Group Code	EC50	2	days	>0.9～<1.2						16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim	Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms	Water Res.27(2): 199-204	1993	2016/03/25
甲殻類	Daphnia magna	No Group Code	EC50	2	days	>0.9～<1.2						16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim	Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms	Water Res.27(2): 199-204	1993	2016/03/25
甲殻類	Daphnia magna	Mortality	EC50	2	days	7900	μg/L					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Brooke,L.T.	Results of Freshwater Exposures with the Chemicals Atrazine, Biphenyl, Butachlor, Carbaryl, Carbazole, Dibenzofuran, 3,3'-Dichlorobenzidine, Dichlorvos, 1,2-Epoxyethylbenzene (Styrene Oxide), Isophorone, Isopropalin, Oxy	Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI:110 p.	1991	2016/03/25
甲殻類	Chironomus tentans	Survival	LOEC	14	days	0.2	mg/L					19 その他		Brominated Flame Retardants Industry Panel	The subchronic toxicity of sediment-sorbed tetrabromobisphenol A to Chironomus tentans under flow-through conditions.	Amended Final Report. Springborn Laboratories, Inc. Report #89-08-3067, Study #1199-1287-6107-128. October 6, 1989.		2021/04/14
甲殻類	Chironomus tentans		LC50	14	days	0.13	mg/L					19 その他		Brominated Flame Retardants Industry Panel	The subchronic toxicity of sediment-sorbed tetrabromobisphenol A to Chironomus tentans under flow-through conditions.	Amended Final Report. Springborn Laboratories, Inc. Report #89-08-3067, Study #1199-1287-6107-128. October 6, 1989.		2021/04/14
甲殻類	Chironomus tentans	Growth(Weight)	NOEC	14	days	0.045	AI mg/L			<0.0075-<0.0077 AI mg/L / <0.0074-<0.0075 AI mg/L		16 ECOTOX		Springborn Laboratories Inc.	The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689	EPA/OTS Doc.#40-8998109		2020/11/12
甲殻類	Chironomus tentans	Survival	NOEC	14	days	0.045	AI mg/L			<0.0075-<0.0077 AI mg/L / <0.0074-<0.0075 AI mg/L		16 ECOTOX		Springborn Laboratories Inc.	The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689	EPA/OTS Doc.#40-8998109		2020/11/12
甲殻類	Chironomus tentans	Growth(Weight)	NOEC	14	days	0.045	AI mg/L			<0.0075-<0.0077 AI mg/L / <0.0074-<0.0075 AI mg/L		16 ECOTOX		Springborn Laboratories Inc.	The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689	EPA/OTS Doc.#40-8998109		2020/11/12
甲殻類	Chironomus tentans		NOEL	14	days	0.045	mg/L	×			0.0075-0.045 mg/L	19 その他		IPCS	Environmental health criteria 172, Tetrabromobisphenol A and derivatives	Geneva, World Health Organization		2021/04/13
甲殻類	Chironomus tentans	Growth(Weight)	NOEC	14	days	0.046	AI mg/L			<0.00042-<0.0011 AI mg/L / <0.00041-<0.00048 AI mg		16 ECOTOX		Springborn Laboratories Inc.	The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689	EPA/OTS Doc.#40-8998109		2020/11/12
甲殻類	Chironomus tentans	Growth(Weight)	NOEC	14	days	0.046	AI mg/L			<0.00042-<0.0011 AI mg/L / <0.00041-<0.00048 AI mg		16 ECOTOX		Springborn Laboratories Inc.	The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689	EPA/OTS Doc.#40-8998109		2020/11/12
甲殻類	Chironomus tentans	Mortality	LC50	14	days	0.13	AI mg/L			<0.023-<0.024 AI mg/L / <0.022-<0.024 AI mg/L / 0.		16 ECOTOX		Springborn Laboratories Inc.	The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689	EPA/OTS Doc.#40-8998109		2020/11/12
甲殻類	Chironomus tentans	Growth(Weight)	LOEC	14	days	0.066	AI mg/L			<0.023-<0.024 AI mg/L / <0.022-<0.024 AI mg/L / 0.		16 ECOTOX		Springborn Laboratories Inc.	The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689	EPA/OTS Doc.#40-8998109		2020/11/12
甲殻類	Chironomus tentans	Survival	NOEC	14	days	0.12	AI mg/L			<0.023-<0.024 AI mg/L / <0.022-<0.024 AI mg/L / 0.		16 ECOTOX		Springborn Laboratories Inc.	The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689	EPA/OTS Doc.#40-8998109		2020/11/12
甲殻類	Chironomus tentans	Survival	NOEC	14	days	0.046	AI mg/L			<0.0074-<0.0079 AI mg/L / <0.0074-<0.0075 AI mg/L		16 ECOTOX		Springborn Laboratories Inc.	The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689	EPA/OTS Doc.#40-8998109		2020/11/12
甲殻類	Chironomus tentans	Growth(Weight)	NOEC	14	days	0.046	AI mg/L			<0.0074-<0.0079 AI mg/L / <0.0074-<0.0075 AI mg/L		16 ECOTOX		Springborn Laboratories Inc.	The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689	EPA/OTS Doc.#40-8998109		2020/11/12
甲殻類	Chironomus tentans	Growth(Weight)	NOEC	14	days	0.046	AI mg/L			<0.0074-<0.0079 AI mg/L / <0.0074-<0.0075 AI mg/L		16 ECOTOX		Springborn Laboratories Inc.	The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689	EPA/OTS Doc.#40-8998109		2020/11/12
甲殻類	Chironomus tentans	Growth(Weight)	MATC	14	days	0.07	AI mg/L			<0.023-<0.024 AI mg/L / <0.022-<0.024 AI mg/L / 0.		16 ECOTOX		Springborn Laboratories Inc.	The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689	EPA/OTS Doc.#40-8998109		2020/11/12
甲殻類	Chironomus tentans	Survival	LOEC	14	days	0.2	AI mg/L			<0.023-<0.024 AI mg/L / <0.022-<0.024 AI mg/L / 0.		16 ECOTOX		Springborn Laboratories Inc.	The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689	EPA/OTS Doc.#40-8998109		2020/11/12
甲殻類	Chironomus tentans	Survival	NOEC	14	days	0.046	AI mg/L			<0.00042-<0.0011 AI mg/L / <0.00041-<0.00048 AI mg		16 ECOTOX		Springborn Laboratories Inc.	The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689	EPA/OTS Doc.#40-8998109		2020/11/12
甲殻類	Chironomus tentans		NOEL	14	days	0.046	mg/L	×			0.0078-0.046 mg/L	19 その他		IPCS	Environmental health criteria 172, Tetrabromobisphenol A and derivatives	Geneva, World Health Organization		2021/04/13
甲殻類	Chironomus tentans		NOEL	14	days	0.046	mg/L	×			0.0044-0.046 mg/L	19 その他		IPCS	Environmental health criteria 172, Tetrabromobisphenol A and derivatives	Geneva, World Health Organization		2021/04/13
甲殻類	Daphnia magna		EC50	48	hours	1000	μg/L					14 BUA Report		Lee SK, Freitag, D, Steinberg C, Kettrup A, Kim YH	Effects of dissolved humic material on acute toxicity of some organic chemicals to aquatic organisms.	Wat Res 27(2)	1993	2020/01/21
甲殻類	Daphnia magna	Immobilization	EC0	48	hours	3.6	mg/L			0, 2.00, 3.60, 6.30, 11.0, 20.0mg/l	設定値の96～98％（0h)、97～99％（48h)	18 既存化学物質安全性(ハザード)評価シート		環境省	既存化学物質審査シート（三監No.10）			2020/01/08
甲殻類	Daphnia magna	Immobilization	EC50	48	hours	7.87	mg/L			0, 2.00, 3.60, 6.30, 11.0, 20.0mg/l	設定値の96～98％（0h)、97～99％（48h)	18 既存化学物質安全性(ハザード)評価シート		環境省	既存化学物質審査シート（三監No.10）			2020/01/08
甲殻類	Daphnia magna		EC50	48	hours	960	μg/L					14 BUA Report		Velsicol Chemical Corporation	The acute toxicity of tetrabromobisphenol A to the water flea, Daphnia magna Straus. UCES Project: 11506-03-52		1978	2020/01/22
甲殻類	Daphnia magna	Immob.	EC50	48	hours	1	μg/L					7 EU Risk Assessment Report (EUリスク評価書）	3	Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.	Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.	Water Research, 27	1993	2019/12/27
甲殻類	Daphnia magna		EC50	48	hours	0.96	mg/L					4 OECD SIDS (HPVC)						2020/01/17
甲殻類	Daphnia magna	Immob.	EC50	48	hours	0.94	μg/L					7 EU Risk Assessment Report (EUリスク評価書）	3	Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.	Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.	Water Research, 27	1993	2019/12/27
甲殻類	Daphnia magna	Immobilisation	EC50	16	days	1000～2000	μg/L			310, 630, 1300, 2500, 5000µg/l		14 BUA Report		Great Lakes Chemical Corporation	The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions. Springborn Laboratories, SLS Report: 89-1-2925		1989	2020/01/22
甲殻類	Nitocra spinipes	Larval development	EC0	96	hours	>=35	μg/L					14 BUA Report		Breitholtz M, Wollenberger L, Bengtsson BE, Kusk OK	Impacts of brominated flame retardants on development and reproduction of two copepod species, Nitocra spinipes and Acartia tonsa.	The Second International Workshop on Brominated Flame Retardants, May 14-16, 2001, Stockholm, Sweden, abstract volume	2001	2020/01/22
甲殻類	Daphnia magna	Mortality	LC50	48	hours	0.96	mg/L			0.32, 0.56, 1.00, 1.80 and 3.20mg/l plus control and solvent control		7 EU Risk Assessment Report (EUリスク評価書）	2	Union Carbide Corporation	The acute toxicity of FMBP 4A (tetrabromobisphenol A) to the water flea Daphnia magna Straus.	UCES Project Number 11506-03-52. Union Carbide Environmental Services, New York.	1978	2019/12/24
甲殻類	Daphnia magna		NOEC	48	hours	<0.32	mg/L					14 BUA Report		Velsicol Chemical Corporation	The acute toxicity of tetrabromobisphenol A to the water flea, Daphnia magna Straus. UCES Project: 11506-03-52		1978	2020/01/21
甲殻類	Crassostrea virginica	Shell deposition	EC50	96	hours	0.12	mg/L				0.075, 0.100, 0.160, 0.260,0.310mg/l, control, acetone control	7 EU Risk Assessment Report (EUリスク評価書）	2	Springborn Life Sciences	Acute toxicity of tetrabromobisphenol A to eastern oysters (Crassostrea virginica) under flow-through conditions.	Report No 89-1-2898. Springborn Life Sciences, Inc., Wareham, Massachusetts	1989	2019/12/27
甲殻類	Daphnia magna	Immobilization	EC100	48	hours	20	mg/L		○	対照区，助剤対照区，2.00, 3.60, 6.30, 11.0, 20.0mg/l	1.96, 3.47, 6.12, 10.6, 19.6mg/l	1 日本環境省　生態リスク初期評価						2020/01/08
甲殻類	Daphnia magna	Immobilization	NOEC	48	hours	3.6	mg/L		○	対照区，助剤対照区，2.00, 3.60, 6.30, 11.0, 20.0mg/l	1.96, 3.47, 6.12, 10.6, 19.6mg/l	1 日本環境省　生態リスク初期評価						2020/01/10
甲殻類	Daphnia magna	Immobilization	EC50	48	hours	7.87	mg/L		○	対照区，助剤対照区，2.00, 3.60, 6.30, 11.0, 20.0mg/l	1.96, 3.47, 6.12, 10.6, 19.6mg/l	1 日本環境省　生態リスク初期評価						2020/01/08
甲殻類	Daphnia magna	Immobilization	EC100	24	hours	20	mg/L		○	対照区，助剤対照区，2.00, 3.60, 6.30, 11.0, 20.0mg/l	1.96, 3.47, 6.12, 10.6, 19.6mg/l	1 日本環境省　生態リスク初期評価						2020/01/08
甲殻類	Daphnia magna	Immobilization	NOEC	24	hours	6.3	mg/L		○	対照区，助剤対照区，2.00, 3.60, 6.30, 11.0, 20.0mg/l	1.96, 3.47, 6.12, 10.6, 19.6mg/l	1 日本環境省　生態リスク初期評価						2020/01/10
甲殻類	Daphnia magna	Immob.	EC50	48	hours	7.9	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	4	Brooke L. T.	Results of freshwater exposures with the chemicals atrazine, biphenyl, butachlor, carbaryl, carbazole, dibenzofuran, 3,3-dichlorobenzidine, dichlorvos….	Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.	1991	2019/12/25
甲殻類	Daphnia magna	Immob.	NOEC	48	hours	>=1.8	mg/L			1.2, 1.8mg/l, control, solvent control		7 EU Risk Assessment Report (EUリスク評価書）	1	Wildlife International	Tetrabromobisphenol A: A 48-hour flow-through acute toxicity test with the cladoceran (Daphnia magna).	Wildlife International Ltd., Project Number 439A-124	2003	2019/12/27
甲殻類	Acartia tonsa	Mortality	LC50	48	hours	0.4	mg/L			Six concentrations between 0.1 and 0.5mg/l,control, solvent control		7 EU Risk Assessment Report (EUリスク評価書）	2	Wollenberger L., Dinan L. and Breitholtz M.	Effects of brominated flame retardants on two marine copepod species, Acartia tonsa and Nitocra spinipes, and on the Ecdysterodresponsive Drosophila malanogaster BII-cell-line.	Organohalogen Compounds, 57	2002	2019/12/27
甲殻類	Acartia tonsa	Mortality	LC10	48	hours	0.3	mg/L			Six concentrations between 0.1 and 0.5mg/l, control, solvent control		7 EU Risk Assessment Report (EUリスク評価書）	2	Wollenberger L., Dinan L. and Breitholtz M.	Effects of brominated flame retardants on two marine copepod species, Acartia tonsa and Nitocra spinipes, and on the Ecdysterodresponsive Drosophila malanogaster BII-cell-line.	Organohalogen Compounds, 57	2002	2019/12/27
甲殻類	Daphnia magna	Immobilization	EC50	24	hours	9.25	mg/L		○	対照区，助剤対照区，2.00, 3.60, 6.30, 11.0, 20.0mg/l	1.96, 3.47, 6.12, 10.6, 19.6mg/l	1 日本環境省　生態リスク初期評価						2020/01/08
甲殻類	Daphnia magna	Immob.	EC50	48	hours	0.95	μg/L					7 EU Risk Assessment Report (EUリスク評価書）	3	Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.	Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.	Water Research, 27	1993	2019/12/27
甲殻類	Crassostrea virginica	Shell deposition	EC50	96	hours	0.098	mg/L				0.018, 0.032, 0.051, 0.087, 0.15mg/l, control, acetone control	7 EU Risk Assessment Report (EUリスク評価書）	2	Springborn Life Sciences	Acute toxicity of tetrabromobisphenol A to eastern oysters (Crassostrea virginica) under flow-through conditions.	Report No 89-1-2898. Springborn Life Sciences, Inc., Wareham, Massachusetts	1989	2019/12/27
甲殻類	Daphnia magna	Immob.	EC50	48	hours	0.94	μg/L					7 EU Risk Assessment Report (EUリスク評価書）	3	Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.	Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.	Water Research, 27	1993	2019/12/27
甲殻類	Mysidopsis bahia	Mortality	LC50	96	hours	1.1	mg/L				GC method	7 EU Risk Assessment Report (EUリスク評価書）	2	Goodman L. R., Cripe G. M., Moody P. H. and Halsell D. G.	Acute toxicity of malathion, tetrabromobisphenol-A, and tributyltin chloride to mysids (Mysidopsis bahia) of three ages.	Bull. Environ. Contam. Toxicol., 41	1988	2019/12/27
甲殻類	Acartia tonsa		LC50	48	hours	400	μg/L					14 BUA Report		Breitholtz M, Wollenberger L, Bengtsson BE, Kusk OK	Impacts of brominated flame retardants on development and reproduction of two copepod species, Nitocra spinipes and Acartia tonsa.	The Second International Workshop on Brominated Flame Retardants, May 14-16, 2001, Stockholm, Sweden, abstract volume	2001	2020/01/21
甲殻類	Nitocra spinipes	Larval development	LC50	96	hours	350	μg/L					14 BUA Report		Breitholtz M, Wollenberger L, Bengtsson BE, Kusk OK	Impacts of brominated flame retardants on development and reproduction of two copepod species, Nitocra spinipes and Acartia tonsa.	The Second International Workshop on Brominated Flame Retardants, May 14-16, 2001, Stockholm, Sweden, abstract volume	2001	2020/01/21
甲殻類	Crassostrea virginica	Growth	NOEC	96	hours	6.2	μg/L		○		18, 32, 51, 87, 150µg/l	14 BUA Report		Great Lakes Chemical Corporation	Acute toxicity of tetrabromobisphenol A to eastern oysters (Crassostrea virginica) under flow-through conditions. Springborn Laboratories, SLS Report: 89-1-2898		1989	2020/01/21
甲殻類	Crassostrea virginica	Growth	EC10	96	hours	6.2	μg/L		○		18, 32, 51, 87, 150µg/l	14 BUA Report		Great Lakes Chemical Corporation	Acute toxicity of tetrabromobisphenol A to eastern oysters (Crassostrea virginica) under flow-through conditions. Springborn Laboratories, SLS Report: 89-1-2898		1989	2020/01/21
甲殻類	Mysidopsis bahia		LC50	96	hours	860	μg/L					14 BUA Report		Goodman L, Cripe G, Moody P, Halsell D	Acute toxicity of malathione, tetrabromobisphenol A and tributyltin chloride to Mysids (Mysidopsis bahia) of three ages.	Bull Environ Contam Toxicol 41	1988	2020/01/21
甲殻類	Crassostrea virginica	Shell deposition	EC10	96	hours	0.0026～0.0062	mg/L				0.018, 0.032, 0.051, 0.087, 0.15mg/l, control, acetone control	7 EU Risk Assessment Report (EUリスク評価書）	2	Springborn Life Sciences	Acute toxicity of tetrabromobisphenol A to eastern oysters (Crassostrea virginica) under flow-through conditions.	Report No 89-1-2898. Springborn Life Sciences, Inc., Wareham, Massachusetts	1989	2019/12/27
甲殻類	Crassostrea virginica	Growth	EC50	96	hours	98	μg/L		○		18, 32, 51, 87, 150µg/l	14 BUA Report		Great Lakes Chemical Corporation	Acute toxicity of tetrabromobisphenol A to eastern oysters (Crassostrea virginica) under flow-through conditions. Springborn Laboratories, SLS Report: 89-1-2898		1989	2020/01/21
甲殻類	Mysidopsis bahia	Mortality	LC50	96	hours	0.86	mg/L				GC method	7 EU Risk Assessment Report (EUリスク評価書）	1	Goodman L. R., Cripe G. M., Moody P. H. and Halsell D. G.	Acute toxicity of malathion, tetrabromobisphenol-A, and tributyltin chloride to mysids (Mysidopsis bahia) of three ages.	Bull. Environ. Contam. Toxicol., 41	1988	2019/12/27
甲殻類	Mysidopsis bahia		LC50	96	hours	1200	μg/L					14 BUA Report		Goodman L, Cripe G, Moody P, Halsell D	Acute toxicity of malathione, tetrabromobisphenol A and tributyltin chloride to Mysids (Mysidopsis bahia) of three ages.	Bull Environ Contam Toxicol 41	1988	2020/01/21
甲殻類	Mysidopsis bahia		LC50	96	hours	1100	μg/L					14 BUA Report		Goodman L, Cripe G, Moody P, Halsell D	Acute toxicity of malathione, tetrabromobisphenol A and tributyltin chloride to Mysids (Mysidopsis bahia) of three ages.	Bull Environ Contam Toxicol 41	1988	2020/01/21
甲殻類	Nitocra spinipes	Mortality	LC50	96	hours	0.35	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Breitholtz M., Wollenberger L., Bengtsson B-E. and Kusk K. O.	Impact of brominated flame retardants on development and reproduction of two copepod species, Nitocra spinipes and Acartia tonsa.	Second International Workshop on Brominated Flame Retardants, May 14-16, Stockholm University, Sweden	2001	2019/12/25
甲殻類	Mysidopsis bahia	Mortality	LC50	96	hours	1.2	mg/L				GC method	7 EU Risk Assessment Report (EUリスク評価書）	2	Goodman L. R., Cripe G. M., Moody P. H. and Halsell D. G.	Acute toxicity of malathion, tetrabromobisphenol-A, and tributyltin chloride to mysids (Mysidopsis bahia) of three ages.	Bull. Environ. Contam. Toxicol., 41	1988	2019/12/27
甲殻類	Mysidopsis bahia	Mortality	LC50	4	days	860	μg/L					6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）	c	Goodman,L.R., G.M.Cripe, P.H.Moody, and D.G.Halsell	Acute Toxicity of Malathion, Tetrabromobisphenol-A, and Tributyltin Chloride to Mysids (Mysidopsis bahia) of Three Ages.	Bull. Environ. Contam. Toxicol. 41(5)	1988	2020/02/14
甲殻類	Daphnia magna	Immobilization	EC50	2	days	7870	μg/L					6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）	a	環境庁	平成11年度　生態影響試験実施事業報告		2000	2020/02/14
甲殻類	Daphnia magna	IntoxicationImmobile	EC50 EC50	48	hours	>0.9～<1.2	μg/L [Active ingredient]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim	Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms	Water Res.27(2)	1993
甲殻類	Americamysis bahia	MortalityMortality	LC50 LC50	96	hours	860	μg/L [Active ingredient]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Goodman,L.R., G.M. Cripe, P.H. Moody, and D.G. Halsell	Acute Toxicity of Malathion, Tetrabromobisphenol-A, and Tributyltin Chloride to Mysids (Mysidopsis bahia) of Three Ages	Bull. Environ. Contam. Toxicol.41(5)	1988
甲殻類	Daphnia magna	MortalityMortality	EC50 EC50	48	hours	7900	μg/L [Active ingredient]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Brooke,L.T.	Results of Freshwater Exposures with the Chemicals Atrazine, Biphenyl, Butachlor, Carbaryl, Carbazole, Dibenzofuran, 3,3'-Dichlorobenzidine, Dichlorvos, 1,2-Epoxyethylbenzene (Styrene Oxide), Isophorone, Isopropalin, Ox	Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI	1991
甲殻類	Americamysis bahia	MortalityMortality	LC50 LC50	96	hours	1200	μg/L [Active ingredient]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Goodman,L.R., G.M. Cripe, P.H. Moody, and D.G. Halsell	Acute Toxicity of Malathion, Tetrabromobisphenol-A, and Tributyltin Chloride to Mysids (Mysidopsis bahia) of Three Ages	Bull. Environ. Contam. Toxicol.41(5)	1988
甲殻類	Americamysis bahia	MortalityMortality	LC50 LC50	96	hours	1100	μg/L [Active ingredient]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Goodman,L.R., G.M. Cripe, P.H. Moody, and D.G. Halsell	Acute Toxicity of Malathion, Tetrabromobisphenol-A, and Tributyltin Chloride to Mysids (Mysidopsis bahia) of Three Ages	Bull. Environ. Contam. Toxicol.41(5)	1988
甲殻類	Daphnia magna	IntoxicationImmobile	EC50 EC50	48	hours	>0.9～<1.2	μg/L [Active ingredient]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim	Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms	Water Res.27(2)	1993
甲殻類	Daphnia magna	IntoxicationImmobile	EC50 EC50	48	hours	>0.9～<1.2	μg/L [Active ingredient]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim	Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms	Water Res.27(2)	1993
甲殻類	Daphnia magna	IntoxicationImmobile	EC50 EC50	24	hours	>1.8	mg/L [Active ingredient]				<0.250 AI mg/L / <0.250 AI mg/L / 1.2 (1.18-1.25) AI mg/L / 1.8 (1.71-1.85) AI mg/L	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Wildlife International Ltd.	Tetrabromobisphenol A: A 48-Hour Flow-Through Acute Toxicity Test with the Cladoceran (Daphnia magna)	Wildlife International, LTD. Project Number	2003
甲殻類	Daphnia magna	IntoxicationImmobile	EC50 EC50	48	hours	>1.8	mg/L [Active ingredient]				<0.250 AI mg/L / <0.250 AI mg/L / 1.2 (1.18-1.25) AI mg/L / 1.8 (1.71-1.85) AI mg/L	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Wildlife International Ltd.	Tetrabromobisphenol A: A 48-Hour Flow-Through Acute Toxicity Test with the Cladoceran (Daphnia magna)	Wildlife International, LTD. Project Number	2003
甲殻類	Daphnia magna	IntoxicationImmobile	EC50 EC50	48	hours	>0.9～<1.2	μg/L [Active ingredient]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim	Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms	Water Res.27(2)	1993
甲殻類	Daphnia magna	IntoxicationImmobile	NOEC NOEC	48	hours	1.8	mg/L [Active ingredient]				<0.250 AI mg/L / <0.250 AI mg/L / 1.2 (1.18-1.25) AI mg/L / 1.8 (1.71-1.85) AI mg/L	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Wildlife International Ltd.	Tetrabromobisphenol A: A 48-Hour Flow-Through Acute Toxicity Test with the Cladoceran (Daphnia magna)	Wildlife International, LTD. Project Number	2003
甲殻類	Daphnia magna	mortality	NOEC	48	hours	<0.32	mg/L [nominal, test mat.]		×	control, solvent control, 0.32, 0.56, 1.00, 1.80, 3.20 mg/L		12 ECHA Information on Registered Substances	4		study report		1978	2020/03/18
甲殻類	Daphnia magna	mortality	LC50	48	hours	>1.8	mg/L		○	1.2, 1.8 mg a.i./L	1.2, 1.8 mg a.i./L	12 ECHA Information on Registered Substances	1		study report		2003
甲殻類	Daphnia magna	mortality	NOEC	48	hours	1.8	mg/L		○	1.2, 1.8 mg a.i./L	1.2, 1.8 mg a.i./L	12 ECHA Information on Registered Substances	1		study report		2003
甲殻類	Daphnia magna	mortality	LC50	24	hours	>1.8	mg/L		○	1.2, 1.8 mg a.i./L	1.2, 1.8 mg a.i./L	12 ECHA Information on Registered Substances	1		study report		2003
甲殻類	Daphnia magna	mortality	LC50	48	hours	0.96	mg/L		×	control, solvent control, 0.32, 0.56, 1.00, 1.80, 3.20 mg/L		12 ECHA Information on Registered Substances	4		study report		1978
甲殻類	Daphnia magna	mortality	NOEC	48	hours	<0.32	mg/L		×	control, solvent control, 0.32, 0.56, 1.00, 1.80, 3.20 mg/L		12 ECHA Information on Registered Substances	4		study report		1978
甲殻類	Acartia tonsa	mortality	LC10	48	hours	300	μg/L		×	100 - 500 µg/L		12 ECHA Information on Registered Substances	2	Wollenberger L, Dinan L & Breitholtz M	BROMINATED FLAME RETARDANTS: ACTIVITIES IN A CRUSTACEAN DEVELOPMENT TEST AND IN AN ECDYSTEROID SCREENING ASSAY	Environ. Toxicol. Chem. 24	2005
甲殻類	Acartia tonsa	mortality	LC50	48	hours	400	μg/L		×	100 - 500 µg/L		12 ECHA Information on Registered Substances	2	Wollenberger L, Dinan L & Breitholtz M	BROMINATED FLAME RETARDANTS: ACTIVITIES IN A CRUSTACEAN DEVELOPMENT TEST AND IN AN ECDYSTEROID SCREENING ASSAY	Environ. Toxicol. Chem. 24	2005
甲殻類	Daphnia magna	mortality	LC50	48	hours	0.96	mg/L [nominal]		×	control, solvent control, 0.32, 0.56, 1.00, 1.80, 3.20 mg/L		12 ECHA Information on Registered Substances	4		study report		1978	2020/03/18
甲殻類	Daphnia magna	mortality	LC50	48	hours	>1.8	mg/L					12 ECHA Information on Registered Substances			study report			2021/03/02
甲殻類	Daphnia magna	mortality	LC50	24	hours	>1.8	mg/L					12 ECHA Information on Registered Substances			study report			2021/03/02
甲殻類	Daphnia magna	mortality	NOEC	48	hours	1.8	mg/L					12 ECHA Information on Registered Substances			study report			2021/03/02
甲殻類	Daphnia magna	mortality	NOEC	48	hours	<0.32	mg/L					12 ECHA Information on Registered Substances			study report			2021/03/02
甲殻類	Daphnia magna	mortality	LC50	48	hours	0.96	mg/L					12 ECHA Information on Registered Substances			study report			2021/03/02
甲殻類	Daphnia magna		EC50	48	hours	7.9	mg/L					1 日本環境省　生態リスク初期評価		環境省	（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）			2016/11/09
甲殻類	Daphnia magna	immobility	EC50	48	hours	0.94	μg/L					7 EU Risk Assessment Report (EUリスク評価書）	3	Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.	Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.	Water Research, 27 Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.	1993	2016/03/04
甲殻類	Daphnia magna	遊泳阻害	EiC50	48	hours	7.87	mg/L					11 Japan チャレンジプログラム		-	4，4'-イソプロピリデンビス（2，6一ジブロモフェノール）のオオミジンコ（Daphnia magna）に対する急性遊泳阻害試験	9B456G		2016/03/08
甲殻類	Daphnia magna	遊泳阻害	NOECi	48	hours	3.6	mg/L					11 Japan チャレンジプログラム		-	4，4'-イソプロピリデンビス（2，6一ジブロモフェノール）のオオミジンコ（Daphnia magna）に対する急性遊泳阻害試験	9B456G		2016/03/08
甲殻類	Daphnia magna	遊泳阻害	EiC100	24	hours	20	mg/L					11 Japan チャレンジプログラム		-	4，4'-イソプロピリデンビス（2，6一ジブロモフェノール）のオオミジンコ（Daphnia magna）に対する急性遊泳阻害試験	9B456G		2016/03/08
甲殻類	Daphnia magna	mortality	LC50	48	hours	0.96	mg/L					10 EHC (Environmental Health Criteria)		Morrissey AE	The acute toxicity of FMBP4A (tetrabromobisphenol A) to the water flea, Daphnia magna Straus.	Tarrytown, New York, Union Carbide Corporation, Environmental Services (Report to Velsicol Chemical Corporation, Chicago, submitted to WHO by the Brominated Flame Retardant Industry Panel)	1978	2016/03/04
甲殻類	Daphnia magna	Mortality	LC50	48	hours	0.96	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Union Carbide Corporation	The acute toxicity of FMBP 4A (tetrabromobisphenol A) to the water flea Daphnia magna Straus.	UCES Project Number 11506-03-52. Union Carbide Environmental Services, New York. Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.	1978	2016/03/04
甲殻類	Daphnia magna	immobility	EC50	48	hours	1	μg/L					7 EU Risk Assessment Report (EUリスク評価書）	3	Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.	Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.	Water Research, 27 Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.	1993	2016/03/04
甲殻類	Daphnia magna	immobility	EC50	48	hours	0.94	μg/L					7 EU Risk Assessment Report (EUリスク評価書）	3	Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.	Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.	Water Research, 27 Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.	1993	2016/03/04
甲殻類	Daphnia magna	immobility	EC50	48	hours	7.9	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	4	Brooke L. T.	Results of freshwater exposures with the chemicals atrazine, biphenyl, butachlor, carbaryl, carbazole, dibenzofuran, 3,3-dichlorobenzidine, dichlorvos….	Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database. Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.	1991	2016/03/04
甲殻類	Daphnia magna	immobility	EC50	48	hours	0.95	μg/L					7 EU Risk Assessment Report (EUリスク評価書）	3	Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.	Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.	Water Research, 27 Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.	1993	2016/03/04
甲殻類	Daphnia magna	Immobilization	EC50	2	days	7870	μg/L					6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）	a	環境庁	平成 11 年度　生態影響試験実施事業報告		2000	2016/03/05
甲殻類	Daphnia magna	遊泳阻害	EiC100	48	hours	14	mg/L					11 Japan チャレンジプログラム		-	2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンのオオミジンコ（Daphnia magna）に対する急性遊泳阻害試験	EDI95005		2016/03/08
甲殻類	Daphnia magna	遊泳阻害	EiC50	48	hours	6.3	mg/L					11 Japan チャレンジプログラム		-	2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンのオオミジンコ（Daphnia magna）に対する急性遊泳阻害試験	EDI95005		2016/03/08
甲殻類	Daphnia magna	遊泳阻害	EiC50	24	hours	18	mg/L					11 Japan チャレンジプログラム		-	2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンのオオミジンコ（Daphnia magna）に対する急性遊泳阻害試験	EDI95005		2016/03/08
甲殻類	Daphnia magna	遊泳阻害	NOECi	24	hours	6.3	mg/L					11 Japan チャレンジプログラム		-	4，4'-イソプロピリデンビス（2，6一ジブロモフェノール）のオオミジンコ（Daphnia magna）に対する急性遊泳阻害試験	9B456G		2016/03/08
甲殻類	Daphnia magna	遊泳阻害	EiC50	24	hours	9.25	mg/L					11 Japan チャレンジプログラム		-	4，4'-イソプロピリデンビス（2，6一ジブロモフェノール）のオオミジンコ（Daphnia magna）に対する急性遊泳阻害試験	9B456G		2016/03/08
甲殻類	Daphnia magna	遊泳阻害	EiC100	48	hours	20	mg/L					11 Japan チャレンジプログラム		-	4，4'-イソプロピリデンビス（2，6一ジブロモフェノール）のオオミジンコ（Daphnia magna）に対する急性遊泳阻害試験	9B456G		2016/03/08
甲殻類	Daphnia magna	遊泳阻害	NOECi	48	hours	1	mg/L					11 Japan チャレンジプログラム		-	2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンのオオミジンコ（Daphnia magna）に対する急性遊泳阻害試験	EDI95005		2016/03/08
甲殻類	Daphnia magna		EC50	48	hours	0.96	mg/L					4 OECD SIDS (HPVC)						2016/02/19
甲殻類	Mysidopsis bahia	Mortality	LC50	96	hours	860	μg/L	×				19 その他		IPCS	Environmental health criteria 172, Tetrabromobisphenol A and derivatives	Geneva, World Health Organization		2021/04/13
甲殻類	Acartia tonsa	Mortality	LC75	48	hours	0.39394	mg/L			0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Crassostrea virginica	Shell deposition	NOEC	96	hours	6.2	AI μg/L			<3.3 AI ug/L / <3.3 AI ug/L / 18 (14-21) AI ug/L /		16 ECOTOX		Great Lakes Chemical Corp.	Acute Toxicity of Tetrabromobisphenol A to Eastern Oysters (Crassostrea virginica) Under Flow-Through Conditions with Cover Letters Dated 021489 and 021789	EPA/OTS 40-8998102		2020/11/12
甲殻類	Crassostrea virginica	Shell deposition	NOEC	96	hours	2.6	AI μg/L			<3.3 AI ug/L / <3.3 AI ug/L / 18 (14-21) AI ug/L /		16 ECOTOX		Great Lakes Chemical Corp.	Acute Toxicity of Tetrabromobisphenol A to Eastern Oysters (Crassostrea virginica) Under Flow-Through Conditions with Cover Letters Dated 021489 and 021789	EPA/OTS 40-8998102		2020/11/12
甲殻類	Daphnia magna	Immobile	EC50	48	hours	>0.9～1.2	μg/L					16 ECOTOX		Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim	Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms	Water Res.27(2)		2020/11/12
甲殻類	Acartia tonsa	Mortality	LC25	48	hours	0.15662	mg/L			0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Daphnia magna	Mortality	LC50	48	hours	1.336	mg/L			0 mg/L / 0 mg/L / 0.05 mg/L / 0.1 mg/L / 0.2 mg/L		16 ECOTOX		Yang,S.W., Z.G. Yan, F.F. Xu, S.R. Wang, and F.C. Wu	Development of Freshwater Aquatic Life Criteria for Tetrabromobisphenol A in China	Environ. Pollut.169		2020/11/12
甲殻類	Acartia tonsa	Mortality	LC50	48	hours	0.30453	mg/L			0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Daphnia magna	Mortality	LC50	24	hours	3.21	mg/L			0 mg/L / 0 mg/L / 0.32 mg/L / 0.56 mg/L / 1.00 mg/		16 ECOTOX		Great Lakes Chemical Corp.	Acute Toxicity of FMBP4A (Tetrabromobisphenol A) to the Water Flea Daphnia magna Straus	EPA/OTS 878216112		2020/11/12
甲殻類	Acartia tonsa	Survival	NOEC	5	hours	200	μg/L			0 ug/L / 2 ug/L / 5 ug/L / 13 ug/L / 32 ug/L / 80		16 ECOTOX		Wollenberger,L., L. Dinan, and M. Breitholtz	Brominated Flame Retardants: Activities in a Crustacean Development Test and in an Ecdysteroid Screening Assay	Environ. Toxicol. Chem.24(2)		2020/11/12
甲殻類	Acartia tonsa	Mortality	LC75	48	hours	0.30413	mg/L			0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Daphnia magna	Immobile	EC50	24	hours	0.45	mg/L			0.00 mg/L / 0.04 mg/L / 0.14 mg/L / 0.32 mg/L / 0.		16 ECOTOX		He,Q., X. Wang, P. Sun, Z. Wang, and L. Wang	Acute and Chronic Toxicity of Tetrabromobisphenol A to Three Aquatic Species Under Different pH Conditions	Aquat. Toxicol.164		2020/11/12
甲殻類	Acartia tonsa	Mortality	LC90	48	hours	0.50074	mg/L			0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Acartia tonsa	Development//Slowed, Retarded, Delayed or Non-development	EC10	5	hours	12.7	μg/L			0 ug/L / 2 ug/L / 5 ug/L / 13 ug/L / 32 ug/L / 80		16 ECOTOX		Wollenberger,L., L. Dinan, and M. Breitholtz	Brominated Flame Retardants: Activities in a Crustacean Development Test and in an Ecdysteroid Screening Assay	Environ. Toxicol. Chem.24(2)		2020/11/12
甲殻類	Acartia tonsa	Mortality	LC90	48	hours	0.38778	mg/L			0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Acartia tonsa	Development//Slowed, Retarded, Delayed or Non-development	EC50	5	hours	125	μg/L			0 ug/L / 2 ug/L / 5 ug/L / 13 ug/L / 32 ug/L / 80		16 ECOTOX		Wollenberger,L., L. Dinan, and M. Breitholtz	Brominated Flame Retardants: Activities in a Crustacean Development Test and in an Ecdysteroid Screening Assay	Environ. Toxicol. Chem.24(2)		2020/11/12
甲殻類	Acartia tonsa	Mortality	NOEC	5	hours	200	μg/L			0 ug/L / 2 ug/L / 5 ug/L / 13 ug/L / 32 ug/L / 80		16 ECOTOX		Wollenberger,L., L. Dinan, and M. Breitholtz	Brominated Flame Retardants: Activities in a Crustacean Development Test and in an Ecdysteroid Screening Assay	Environ. Toxicol. Chem.24(2)		2020/11/12
甲殻類	Acartia tonsa	Mortality	LC50	48	hours	0.2112	mg/L			0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Daphnia magna	Immobile	EC50	24	hours	2.7	mg/L			0.00 mg/L / 2.00 mg/L / 2.50 mg/L / 3.50 mg/L / 5.		16 ECOTOX		He,Q., X. Wang, P. Sun, Z. Wang, and L. Wang	Acute and Chronic Toxicity of Tetrabromobisphenol A to Three Aquatic Species Under Different pH Conditions	Aquat. Toxicol.164		2020/11/12
甲殻類	Crassostrea virginica	Shell deposition	EC50			0.098	mg/L	×		0.018-0.15 mg/L		19 その他		IPCS	Environmental health criteria 172, Tetrabromobisphenol A and derivatives	Geneva, World Health Organization		2021/04/13
甲殻類	Daphnia magna	Mortality	LC50	48	hours	0.96	mg/L	×				19 その他		IPCS	Environmental health criteria 172, Tetrabromobisphenol A and derivatives	Geneva, World Health Organization		2021/04/13
甲殻類	Mysidopsis bahia	Mortality	LC50	96	hours	1100	μg/L	×				19 その他		IPCS	Environmental health criteria 172, Tetrabromobisphenol A and derivatives	Geneva, World Health Organization		2021/04/13
甲殻類	Mysidopsis bahia	Mortality	LC50	96	hours	1200	μg/L	×				19 その他		IPCS	Environmental health criteria 172, Tetrabromobisphenol A and derivatives	Geneva, World Health Organization		2021/04/13
甲殻類	Daphnia magna	Immobile	EC50	24	hours	25.33	mg/L			0.00 mg/L / 10.00 mg/L / 15.00 mg/L / 20.00 mg/L /		16 ECOTOX		He,Q., X. Wang, P. Sun, Z. Wang, and L. Wang	Acute and Chronic Toxicity of Tetrabromobisphenol A to Three Aquatic Species Under Different pH Conditions	Aquat. Toxicol.164		2020/11/12
甲殻類	Crassostrea virginica	Shell deposition	NOEC			0.018	mg/L	×		0.018-0.15 mg/L		19 その他		IPCS	Environmental health criteria 172, Tetrabromobisphenol A and derivatives	Geneva, World Health Organization		2021/04/13
甲殻類	Crassostrea virginica	Shell deposition	EC50	96	hours	120	AI μg/L			0 AI ug/L / 0 AI ug/L / 75 AI ug/L / 100 AI ug/L /		16 ECOTOX		Great Lakes Chemical Corp.	Acute Toxicity of Tetrabromobisphenol A to Eastern Oysters (Crassostrea virginica) Under Flow-Through Conditions with Cover Letters Dated 021489 and 021789	EPA/OTS 40-8998102		2020/11/12
甲殻類	Acartia tonsa	Mortality	LC10	48	hours	0.04982	mg/L			0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Daphnia magna	Immobile	EC50	48	hours	0.6	mg/L			0 mg/L / 0 mg/L / 0.07 mg/L / 0.09 mg/L / 0.24 mg/		16 ECOTOX		Waaijers,S.L., J. Hartmann, A.M. Soeter, R. Helmus, S.A.E. Kools, P. De Voogt, W. Admiraal, J.R. Parsons, and M.H.S. Kr	Toxicity of New Generation Flame Retardants to Daphnia magna	Sci. Total Environ.463		2020/11/12
甲殻類	Daphnia magna	Immobile	EC50	24	hours	3.97	mg/L			0.00 mg/L / 0.40 mg/L / 3.20 mg/L / 5.00 mg/L / 6.		16 ECOTOX		He,Q., X. Wang, P. Sun, Z. Wang, and L. Wang	Acute and Chronic Toxicity of Tetrabromobisphenol A to Three Aquatic Species Under Different pH Conditions	Aquat. Toxicol.164		2020/11/12
甲殻類	Daphnia magna	Immobile	EC50	48	hours	>0.9～1.2	μg/L					16 ECOTOX		Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim	Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms	Water Res.27(2)		2020/11/12
甲殻類	Daphnia magna	Immobile	EC50	24	hours	11.54	mg/L			0.00 mg/L / 4.00 mg/L / 6.00 mg/L / 8.00 mg/L / 10		16 ECOTOX		He,Q., X. Wang, P. Sun, Z. Wang, and L. Wang	Acute and Chronic Toxicity of Tetrabromobisphenol A to Three Aquatic Species Under Different pH Conditions	Aquat. Toxicol.164		2020/11/12
甲殻類	Daphnia magna	Immobile	EC50	24	hours	0.817	mg/L			0.00 mg/L / 0.20 mg/L / 0.50 mg/L / 0.80 mg/L / 1.		16 ECOTOX		He,Q., X. Wang, P. Sun, Z. Wang, and L. Wang	Acute and Chronic Toxicity of Tetrabromobisphenol A to Three Aquatic Species Under Different pH Conditions	Aquat. Toxicol.164		2020/11/12
甲殻類	Daphnia magna	Immobile	EC50	24	hours	17.34	mg/L			0.00 mg/L / 8.00 mg/L / 12.00 mg/L / 16.00 mg/L /		16 ECOTOX		He,Q., X. Wang, P. Sun, Z. Wang, and L. Wang	Acute and Chronic Toxicity of Tetrabromobisphenol A to Three Aquatic Species Under Different pH Conditions	Aquat. Toxicol.164		2020/11/12
甲殻類	Daphnia magna	Immobile	EC50	24	hours	0.31	mg/L			0.00 mg/L / 0.15 mg/L / 0.16 mg/L / 0.20 mg/L / 0.		16 ECOTOX		He,Q., X. Wang, P. Sun, Z. Wang, and L. Wang	Acute and Chronic Toxicity of Tetrabromobisphenol A to Three Aquatic Species Under Different pH Conditions	Aquat. Toxicol.164		2020/11/12
甲殻類	Acartia tonsa	Mortality	LC25	48	hours	0.11826	mg/L			0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Daphnia magna	Immobile	EC50	24	hours	8.63	mg/L			0.00 mg/L / 5.00 mg/L / 7.00 mg/L / 8.00 mg/L / 9.		16 ECOTOX		He,Q., X. Wang, P. Sun, Z. Wang, and L. Wang	Acute and Chronic Toxicity of Tetrabromobisphenol A to Three Aquatic Species Under Different pH Conditions	Aquat. Toxicol.164		2020/11/12
甲殻類	Acartia tonsa	Development//Slowed, Retarded, Delayed or Non-development	LOEC	5	hours	200	μg/L			0 ug/L / 2 ug/L / 5 ug/L / 13 ug/L / 32 ug/L / 80		16 ECOTOX		Wollenberger,L., L. Dinan, and M. Breitholtz	Brominated Flame Retardants: Activities in a Crustacean Development Test and in an Ecdysteroid Screening Assay	Environ. Toxicol. Chem.24(2)		2020/11/12
甲殻類	Acartia tonsa	Mortality	LC10	48	hours	0.03461	mg/L			0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Daphnia magna	Mortality	LOEC	48	hours	0.56	mg/L			0 mg/L / 0 mg/L / 0.32 mg/L / 0.56 mg/L / 1.00 mg/		16 ECOTOX		Great Lakes Chemical Corp.	Acute Toxicity of FMBP4A (Tetrabromobisphenol A) to the Water Flea Daphnia magna Straus	EPA/OTS 878216112		2020/11/12
甲殻類	Acartia tonsa	Mortality	LC95	48	hours	0.56466	mg/L			0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Acartia tonsa	Mortality	LC95	48	hours	0.43784	mg/L			0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Daphnia magna	Immobile	EC50	48	hours	>0.9～1.2	μg/L					16 ECOTOX		Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim	Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms	Water Res.27(2)		2020/11/12
甲殻類	Daphnia magna	Immobile	EC50	24	hours	18.29	mg/L			0.00 mg/L / 10.00 mg/L / 12.00 mg/L / 14.00 mg/L /		16 ECOTOX		He,Q., X. Wang, P. Sun, Z. Wang, and L. Wang	Acute and Chronic Toxicity of Tetrabromobisphenol A to Three Aquatic Species Under Different pH Conditions	Aquat. Toxicol.164		2020/11/12
甲殻類	Daphnia magna	Immobile	EC50	48	hours	>0.9～1.2	μg/L					16 ECOTOX		Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim	Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms	Water Res.27(2)		2020/11/12
甲殻類	Acartia tonsa	Mortality	LC99	48	hours	0.53174	mg/L			0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Daphnia magna		NOEC	48	hours	1.8	mg/L					19 その他		Wildlife International	Tetrabromobisphenol A: A 48-hour flow-through acute toxicity test with the cladoceran (Daphnia magna).	Wildlife International Ltd., Project Number 439A-124 [cited in EU RAR 2008].		2021/04/14
甲殻類	Acartia tonsa	Mortality	LC50	48	hours	0.4	mg/L					19 その他		Wollenberger L, Dinan L and Breitholtz M	Brominated flame retardants: Activities in a crustacean development test and in an ecdysteroid screening assay.	Environ. Toxicol. Chem. 24		2021/04/14
甲殻類	Acartia tonsa	Development//Slowed, Retarded, Delayed or Non-development	NOEC	5	hours	80	μg/L			0 ug/L / 2 ug/L / 5 ug/L / 13 ug/L / 32 ug/L / 80		16 ECOTOX		Wollenberger,L., L. Dinan, and M. Breitholtz	Brominated Flame Retardants: Activities in a Crustacean Development Test and in an Ecdysteroid Screening Assay	Environ. Toxicol. Chem.24(2)		2020/11/12
甲殻類	Daphnia magna		EC50	72	hours	0.6	mg/L					19 その他		Waaijers SL, Hartmann J, Soeter AM, Helmus R, Kools SAE, de Voogt P, Admiraal W, Parsons JR and Kraak MHS	Toxicity of new generation flame retardants to Daphnia magna	Science of The Total Environment		2021/05/14
甲殻類	Crassostrea virginica		EC50	95	hours	0.02～0.21	mg/L					19 その他		Brominated Flame Retardants Industry Panel	Acute toxicity of tetrabromobisphenol A to Eastern oysters (Crassostrea virginica) under flow-through conditions.	Springborn Life Sciences, Inc. Report #89-1-2898, Study #1199-0688-6106-504. February 15, 1989.		2021/04/14
甲殻類	Mysidopsis bahia	mortality	LC50	96	hours	0.86	mg/L					9 ECETOC Aquatic Toxicity, EAT		Goodman LR, Cripe GM, Moody PH, Halsell DG	Acute toxicity of malathion, tetrabromobisphenol-A and tributyltin chloride to mysids (Mysidopsis bahia) of three ages	Bull Environ Contam Toxicol 41		2020/12/23
甲殻類	Mysidopsis bahia	mortality	LC50	96	hours	0.86	mg/L					9 ECETOC Aquatic Toxicity, EAT		Goodman LR, Cripe GM, Moody PH, Halsell DG	Acute toxicity of malathion, tetrabromobisphenol-A and tributyltin chloride to mysids (Mysidopsis bahia) of three ages	Bull Environ Contam Toxicol 41		2020/12/23
甲殻類	Mysidopsis bahia	mortality	LC50	96	hours	1.1	mg/L					9 ECETOC Aquatic Toxicity, EAT		Goodman LR, Cripe GM, Moody PH, Halsell DG	Acute toxicity of malathion, tetrabromobisphenol-A and tributyltin chloride to mysids (Mysidopsis bahia) of three ages	Bull Environ Contam Toxicol 41		2020/12/23
甲殻類	Mysidopsis bahia	mortality	LC50	96	hours	1.2	mg/L					9 ECETOC Aquatic Toxicity, EAT		Goodman LR, Cripe GM, Moody PH, Halsell DG	Acute toxicity of malathion, tetrabromobisphenol-A and tributyltin chloride to mysids (Mysidopsis bahia) of three ages	Bull Environ Contam Toxicol 41		2020/12/23
甲殻類	Acartia tonsa	Larval development rate	EC50	5	days	125	μg/L			2, 5, 13, 32, 80,200 μg/l, control, solvent control		7 EU Risk Assessment Report (EUリスク評価書）	2	Wollenberger L., Dinan L. and Breitholtz M.	Brominated flame retardants: Activities in a crustacean development test and in an ecdysteroid screening assay.	Environ. Toxicol. Chem., 24	2005	2019/12/27
甲殻類	Chironomus riparius	Mean development time	NOEC	28	days	125	mg/kg dry wt.			63, 125, 250, 500, 1000 mg/kg, control, solvent control		7 EU Risk Assessment Report (EUリスク評価書）	1	Wildlife International	Tetrabromobisphenol-A (TBBPA): A 28-day sediment toxicity test with Chironomus riparius using spiked sediment.	Wildlife International Ltd., Project Number 439A-130.	2005	2019/12/27
甲殻類	Chironomus yoshimatsui	羽化個体数	EC50	25	days	870	mg/kg-dry wt		○	対照区，助剤対照区，56, 100, 180, 320, 560, 1000mg/kg-dry wt	58.1, 101, 191, 364, 618, 1120mg/kg-dry wt	1 日本環境省　生態リスク初期評価						2020/01/14
甲殻類	Daphnia magna		NOEC	21	days	0.3	mg/L					4 OECD SIDS (HPVC)						2020/01/17
甲殻類	Chironomus riparius	Mean emergence ratios	NOEC	28	days	125	mg/kg dry wt.			63, 125, 250, 500, 1000 mg/kg, control, solvent control		7 EU Risk Assessment Report (EUリスク評価書）	1	Wildlife International	Tetrabromobisphenol-A (TBBPA): A 28-day sediment toxicity test with Chironomus riparius using spiked sediment.	Wildlife International Ltd., Project Number 439A-130.	2005	2019/12/27
甲殻類	Chironomus riparius	％ Emerged	EC50	28	days	235	mg/kg dry wt.			63, 125, 250, 500, 1000 mg/kg, control, solvent control		7 EU Risk Assessment Report (EUリスク評価書）	1	Wildlife International	Tetrabromobisphenol-A (TBBPA): A 28-day sediment toxicity test with Chironomus riparius using spiked sediment.	Wildlife International Ltd., Project Number 439A-130.	2005	2019/12/27
甲殻類	Daphnia magna	Reproduction	EC50	21	days	1.66	mg/L		○	対照区，助剤対照区，0.08, 0.25, 0.80, 2.50, 8.00mg/l	0.08, 0.24, 0.86, 2.69, 9.39mg/l	1 日本環境省　生態リスク初期評価						2020/01/10
甲殻類	Chironomus riparius	Abnormal behaviour	NOEC	28	days	125	mg/kg dry wt.			63, 125, 250, 500, 1000 mg/kg, control, solvent control		7 EU Risk Assessment Report (EUリスク評価書）	1	Wildlife International	Tetrabromobisphenol-A (TBBPA): A 28-day sediment toxicity test with Chironomus riparius using spiked sediment.	Wildlife International Ltd., Project Number 439A-130.	2005	2019/12/27
甲殻類	Mytilus edulis	Specific growth rate-shell length	NOEC	70	days	17	μg/L				17, 32, 62, 126, 226 μg/l, control, solvent control	7 EU Risk Assessment Report (EUリスク評価書）	1	Brown R. J., Smyth D. V. and Kent S. J.	TBBPA: Determination of effects on the growth of the common mussel Mytilus edulis.	Brixham Environmental Laboratory Study Number 03-0337/A. Study sponsored by ACC-BFRIP, Arlington, USA.	2005	2019/12/27
甲殻類	Daphnia magna	Reproduction	NOEC	21	days	0.8	mg/L		○	対照区，助剤対照区，0.08, 0.25, 0.80, 2.50, 8.00mg/l	0.08, 0.24, 0.86, 2.69, 9.39mg/l	1 日本環境省　生態リスク初期評価						2020/01/10
甲殻類	Chironomus yoshimatsui	変態速度	EC50	25	days	>1140	mg/kg-dry wt		○	対照区，助剤対照区，56, 100, 180, 320, 560, 1000mg/kg-dry wt	58.1, 101, 191, 364, 618, 1120mg/kg-dry wt	1 日本環境省　生態リスク初期評価						2020/01/14
甲殻類	Daphnia magna	Reproduction	LOEC	21	days	980	μg/L		○		5.6, 100, 190, 300, 980µg/l	14 BUA Report		Great Lakes Chemical Corporation	The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions. Springborn Laboratories, SLS Report: 89-1-2925		1989	2020/01/21
甲殻類	Chironomus yoshimatsui		NOEC	25	days	360	mg/kg-dry wt		○	対照区，助剤対照区，56, 100, 180, 320, 560, 1000mg/kg-dry wt	58.1, 101, 191, 364, 618, 1120mg/kg-dry wt	1 日本環境省　生態リスク初期評価						2020/01/14
甲殻類	Chironomus yoshimatsui		LOEC	25	days	610	mg/kg-dry wt		○	対照区，助剤対照区，56, 100, 180, 320, 560, 1000mg/kg-dry wt	58.1, 101, 191, 364, 618, 1120mg/kg-dry wt	1 日本環境省　生態リスク初期評価						2020/01/14
甲殻類	Daphnia magna	Mortality	LC50	21	days	1.74	mg/L		○	対照区，助剤対照区，0.08, 0.25, 0.80, 2.50, 8.00mg/l	0.08, 0.24, 0.86, 2.69, 9.39mg/l	1 日本環境省　生態リスク初期評価						2020/01/10
甲殻類	Chironomus riparius	Mean development rate	NOEC	28	days	125	mg/kg dry wt.			63, 125, 250, 500, 1000 mg/kg, control, solvent control		7 EU Risk Assessment Report (EUリスク評価書）	1	Wildlife International	Tetrabromobisphenol-A (TBBPA): A 28-day sediment toxicity test with Chironomus riparius using spiked sediment.	Wildlife International Ltd., Project Number 439A-130.	2005	2019/12/27
甲殻類	Daphnia magna	Reproduction	NOEC	21	days	0.8	mg/L			0, 0.08, 0.25, 0.80, 2.50, 8.00mg/l	設定値の88～118％（換水直後)、88～117％（換水直前）	18 既存化学物質安全性(ハザード)評価シート		環境省	既存化学物質審査シート（三監No.10）			2020/01/08
甲殻類	Acartia tonsa	Larval development rate	EC10	5	days	12.7	μg/L			2, 5, 13, 32, 80,200 μg/l, control, solvent control		7 EU Risk Assessment Report (EUリスク評価書）	2	Wollenberger L., Dinan L. and Breitholtz M.	Brominated flame retardants: Activities in a crustacean development test and in an ecdysteroid screening assay.	Environ. Toxicol. Chem., 24	2005	2019/12/27
甲殻類	Acartia tonsa	Larval development	EC50	120	hours	125	μg/L					14 BUA Report		Breitholtz M, Wollenberger L, Bengtsson BE, Kusk OK	Impacts of brominated flame retardants on development and reproduction of two copepod species, Nitocra spinipes and Acartia tonsa.	The Second International Workshop on Brominated Flame Retardants, May 14-16, 2001, Stockholm, Sweden, abstract volume	2001	2020/01/22
甲殻類	Acartia tonsa		NOEC	5	days	0.0127	mg/L					4 OECD SIDS (HPVC)						2020/01/17
甲殻類	Mytilus edulis	Specific growth rate-wet tissue weight	NOEC	70	days	62	μg/L				17, 32, 62, 126, 226 μg/l, control, solvent control	7 EU Risk Assessment Report (EUリスク評価書）	1	Brown R. J., Smyth D. V. and Kent S. J.	TBBPA: Determination of effects on the growth of the common mussel Mytilus edulis.	Brixham Environmental Laboratory Study Number 03-0337/A. Study sponsored by ACC-BFRIP, Arlington, USA.	2005	2019/12/27
甲殻類	Mytilus edulis	Specific growth rate-dry tissue weight	NOEC	70	days	17	μg/L				17, 32, 62, 126, 226 μg/l, control, solvent control	7 EU Risk Assessment Report (EUリスク評価書）	1	Brown R. J., Smyth D. V. and Kent S. J.	TBBPA: Determination of effects on the growth of the common mussel Mytilus edulis.	Brixham Environmental Laboratory Study Number 03-0337/A. Study sponsored by ACC-BFRIP, Arlington, USA.	2005	2019/12/27
甲殻類	Mytilus edulis	Mortality	NOEC	70	days	>=226	μg/L				17, 32, 62, 126, 226 μg/l, control, solvent control	7 EU Risk Assessment Report (EUリスク評価書）	1	Brown R. J., Smyth D. V. and Kent S. J.	TBBPA: Determination of effects on the growth of the common mussel Mytilus edulis.	Brixham Environmental Laboratory Study Number 03-0337/A. Study sponsored by ACC-BFRIP, Arlington, USA.	2005	2019/12/27
甲殻類	Nitocra spinipes	Larval development rate, fecundity, sex ratio	NOEC	18	days	>=0.035	mg/L			Up to 0.035mg/l		7 EU Risk Assessment Report (EUリスク評価書）	2	Wollenberger L., Dinan L. and Breitholtz M.	Effects of brominated flame retardants on two marine copepod species, Acartia tonsa and Nitocra spinipes, and on the Ecdysterodresponsive Drosophila malanogaster BII-cell-line.	Organohalogen Compounds, 57	2002	2019/12/25
甲殻類	Mytilus edulis		NOEC	70	days	0.017	mg/L					4 OECD SIDS (HPVC)						2020/01/17
甲殻類	Daphnia magna	Repro.	NOEC	21	days	0.3	mg/L				0.056, 0.10, 0.19, 0.30, 0.98mg/l, control, solvent control	7 EU Risk Assessment Report (EUリスク評価書）	1	Springborn Laboratories	The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions.	Report No 89-01-2925. Springborn Laboratories, Inc., Wareham, Massachusetts	1989	2019/12/27
甲殻類	Daphnia magna	Reproduction	NOEC	21	days	800	μg/L					6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）	a	環境庁	平成11年度　生態影響試験実施事業報告		2000	2020/02/14
甲殻類	Acartia tonsa	growth	EC10	5	days	12.7	μg/L		×	2, 5, 13, 32, 80, 200 µg/L		12 ECHA Information on Registered Substances	3	Wollenberger L, Dinan L & Breitholtz M	BROMINATED FLAME RETARDANTS: ACTIVITIES IN A CRUSTACEAN DEVELOPMENT TEST AND IN AN ECDYSTEROID SCREENING ASSAY	Environ. Toxicol. Chem. 24	2005
甲殻類	Acartia tonsa	Larval development rate	EC50	5	days	0.125	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	2	Breitholtz M., Wollenberger L., Bengtsson B-E. and Kusk K. O.	Impact of brominated flame retardants on development and reproduction of two copepod species, Nitocra spinipes and Acartia tonsa.	Second International Workshop on Brominated Flame Retardants, May 14-16, Stockholm University, Sweden	2001	2019/12/25
甲殻類	Daphnia magna	Reproduction	LOEC	21	days	2.5	mg/L		○	対照区，助剤対照区，0.08, 0.25, 0.80, 2.50, 8.00mg/l	0.08, 0.24, 0.86, 2.69, 9.39mg/l	1 日本環境省　生態リスク初期評価						2020/01/10
甲殻類	Daphnia magna	Growth	NOEC	21	days	>=0.98	mg/L				0.056, 0.10, 0.19, 0.30, 0.98mg/l, control, solvent control	7 EU Risk Assessment Report (EUリスク評価書）	1	Springborn Laboratories	The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions.	Report No 89-01-2925. Springborn Laboratories, Inc., Wareham, Massachusetts	1989	2019/12/27
甲殻類	Daphnia magna	Reproduction	NOEC	21	days	300	μg/L		○		5.6, 100, 190, 300, 980µg/l	14 BUA Report		Great Lakes Chemical Corporation	The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions. Springborn Laboratories, SLS Report: 89-1-2925		1989	2020/01/21
甲殻類	Daphnia magna	Mortality	NOEC	21	days	>=0.98	mg/L				0.056, 0.10, 0.19, 0.30, 0.98mg/l, control, solvent control	7 EU Risk Assessment Report (EUリスク評価書）	1	Springborn Laboratories	The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions.	Report No 89-01-2925. Springborn Laboratories, Inc., Wareham, Massachusetts	1989	2019/12/27
甲殻類	Acartia tonsa	growth	EC50	5	days	125	μg/L		×	2, 5, 13, 32, 80, 200 µg/L		12 ECHA Information on Registered Substances	3	Wollenberger L, Dinan L & Breitholtz M	BROMINATED FLAME RETARDANTS: ACTIVITIES IN A CRUSTACEAN DEVELOPMENT TEST AND IN AN ECDYSTEROID SCREENING ASSAY	Environ. Toxicol. Chem. 24	2005
甲殻類	Daphnia magna	reproduction	MATC	21	days	>0.3～<0.98	mg/L		○	0.13, 0.25, 0.5, 1.0, 2.0 mg/L	0.037 - 0.078, 0.068 - 0.13, 0.14 - 0.26, 0.19 - 0.29, 0.65 - 1.3 mg/L	12 ECHA Information on Registered Substances	1		study report		1989
甲殻類	Daphnia magna	mortality	EC50	21	days	>0.96	mg/L		○	0.13, 0.25, 0.5, 1.0, 2.0 mg/L	0.037 - 0.078, 0.068 - 0.13, 0.14 - 0.26, 0.19 - 0.29, 0.65 - 1.3 mg/L	12 ECHA Information on Registered Substances	1		study report		1989
甲殻類	Mytilus edulis	growth	NOEC	70	days	17	μg/L		○	19, 38, 75, 150, 300 µg/L	17, 32, 62, 126, 226 µg/L	12 ECHA Information on Registered Substances	1		study report		2005
甲殻類	Daphnia magna	reproduction	NOEC	21	days	0.38	mg/L		○	0.13, 0.25, 0.5, 1.0, 2.0 mg/L	0.037 - 0.078, 0.068 - 0.13, 0.14 - 0.26, 0.19 - 0.29, 0.65 - 1.3 mg/L	12 ECHA Information on Registered Substances	1		study report		1989
甲殻類	Daphnia magna	reproduction	NOEC	21	days	0.38	mg/L					12 ECHA Information on Registered Substances			study report			2021/03/02
甲殻類	Daphnia magna	reproduction	MATC	21	days	>0.3～<0.98	mg/L					12 ECHA Information on Registered Substances			study report			2021/03/02
甲殻類	Daphnia magna	mortality	EC50	21	days	>0.96	mg/L					12 ECHA Information on Registered Substances			study report			2021/03/02
甲殻類	Daphnia magna		EC50	21	days	1.7	mg/L					1 日本環境省　生態リスク初期評価		環境省	（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）			2016/11/10
甲殻類	Daphnia magna		NOEC	21	days	0.8	mg/L					1 日本環境省　生態リスク初期評価		環境省	（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）			2016/11/09
甲殻類	Daphnia magna	immobility	NOEC	48	hours	>=1.8	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	1	Wildlife International	Tetrabromobisphenol A: A 48-hour flow-through acute toxicity test with the cladoceran (Daphnia magna).	Wildlife International Ltd., Project Number 439A-124. Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.	2003	2016/03/04
甲殻類	Daphnia magna		NOEC	21	days	0.3	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	1	Springborn Laboratories	The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions.	Report No 89-01-2925. Springborn Laboratories, Inc., Wareham, Massachusetts.	1989	2016/03/04
甲殻類	Daphnia magna	Mortality	NOEC	21	days	>=0.98	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	1	Springborn Laboratories	The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions.	Report No 89-01-2925. Springborn Laboratories, Inc., Wareham, Massachusetts.	1989	2016/03/04
甲殻類	Daphnia magna	繁殖	EC50	21	days	1.66	mg/L					11 Japan チャレンジプログラム		-	4，4’-イソプロピリデンビス（2，6-ジブロモフェノール）のオオミジンコ（Daphnia magna)に対する繁殖阻害試験	9B478G		2016/03/08
甲殻類	Daphnia magna	Reproduction	NOEC	21	days	800	μg/L					6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）	a	環境庁	平成 11 年度　生態影響試験実施事業報告		2000	2016/03/05
甲殻類	Daphnia magna	Growth	NOEC	21	days	>=0.98	mg/L					7 EU Risk Assessment Report (EUリスク評価書）	1	Springborn Laboratories	The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions.	Report No 89-01-2925. Springborn Laboratories, Inc., Wareham, Massachusetts.	1989	2016/03/04
甲殻類	Daphnia magna	繁殖	LOEC	21	days	2.5	mg/L					11 Japan チャレンジプログラム		-	4，4’-イソプロピリデンビス（2，6-ジブロモフェノール）のオオミジンコ（Daphnia magna)に対する繁殖阻害試験	9B478G		2016/03/08
甲殻類	Daphnia magna	繁殖	LOECr	21	days	0.42	mg/L					11 Japan チャレンジプログラム		-	2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンのオオミジンコ（Daphnia magna)に対する繁殖阻害試験	EDR95005		2016/03/08
甲殻類	Daphnia magna	繁殖	NOEC	21	days	0.8	mg/L					11 Japan チャレンジプログラム		-	4，4’-イソプロピリデンビス（2，6-ジブロモフェノール）のオオミジンコ（Daphnia magna)に対する繁殖阻害試験	9B478G		2016/03/08
甲殻類	Daphnia magna	繁殖	NOECr	21	days	<0.42	mg/L					11 Japan チャレンジプログラム		-	2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンのオオミジンコ（Daphnia magna)に対する繁殖阻害試験	EDR95005		2016/03/08
甲殻類	Daphnia magna	body lengths, Reproduction, mortality		21	days	>0.3～<0.98						10 EHC (Environmental Health Criteria)		Surprenant DC	The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions.	Massachusetts, Springborn Life Sciences, Inc. (Report No. 89-01-2925 submitted to WHO by the Brominated Flame Retardant Industry Panel).	1989	2016/03/04
甲殻類	Daphnia magna	body lengths, Reproduction, mortality		21	days	>0.3～<0.98						10 EHC (Environmental Health Criteria)		Surprenant DC	The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions.	Massachusetts, Springborn Life Sciences, Inc. (Report No. 89-01-2925 submitted to WHO by the Brominated Flame Retardant Industry Panel).	1989	2016/03/04
甲殻類	Daphnia magna	親ミジンコの死亡	LC50	21	days	1.74	mg/L					11 Japan チャレンジプログラム		-	4，4’-イソプロピリデンビス（2，6-ジブロモフェノール）のオオミジンコ（Daphnia magna)に対する繁殖阻害試験	9B478G		2016/03/08
甲殻類	Daphnia magna	親ミジンコの死亡	LC50	21	days	3.9	mg/L					11 Japan チャレンジプログラム		-	2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンのオオミジンコ（Daphnia magna)に対する繁殖阻害試験	EDR95005		2016/03/08
甲殻類	Daphnia magna	繁殖	ErC50	21	days	0.82	mg/L					11 Japan チャレンジプログラム		-	2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンのオオミジンコ（Daphnia magna)に対する繁殖阻害試験	EDR95005		2016/03/08
甲殻類	Daphnia magna		NOEC	21	days	0.3	mg/L					4 OECD SIDS (HPVC)						2016/02/19
甲殻類	Daphnia magna	Mortality	LC50	21	days	0.056～0.98	mg/L	×				19 その他		IPCS	Environmental health criteria 172, Tetrabromobisphenol A and derivatives	Geneva, World Health Organization		2021/04/13
甲殻類	Daphnia magna	Immobile	EC50	21	days	0.98	mg/L			<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg		16 ECOTOX		Great Lakes Chemical Corp.	The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989	EPA/OTS 40-8998117		2020/11/12
甲殻類	Chironomus riparius	Sediment ratio, development rate, development time	NOEC	28	days	125	mg/kg dw [TBBPA]					19 その他		[ACCBFRIP] American Chemistry Council Brominated Flame Retardant Industry Panel	Tetrabromobisphenol-A (TBBPA): A 28-day sediment toxicity test with Chironomus riparius using spiked sediment.	Wildlife International, Ltd. Project Number: 439A-130. July 12, 2005		2021/05/14
甲殻類	Daphnia magna	Reproduction	NOEC	11	days	0.98	mg/L			<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg		16 ECOTOX		Great Lakes Chemical Corp.	The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989	EPA/OTS 40-8998117		2020/11/12
甲殻類	Daphnia magna	Reproduction	EC10	21	days	0.016	mg/L			0 mg/L / 0 mg/L / 0.03 mg/L / 0.04 mg/L / 0.05 mg/		16 ECOTOX		Yang,S.W., Z.G. Yan, F.F. Xu, S.R. Wang, and F.C. Wu	Development of Freshwater Aquatic Life Criteria for Tetrabromobisphenol A in China	Environ. Pollut.169		2020/11/12
甲殻類	Daphnia magna	Mortality//Lifespan	EC10	21	days	0.047	mg/L			0 mg/L / 0 mg/L / 0.03 mg/L / 0.04 mg/L / 0.05 mg/		16 ECOTOX		Yang,S.W., Z.G. Yan, F.F. Xu, S.R. Wang, and F.C. Wu	Development of Freshwater Aquatic Life Criteria for Tetrabromobisphenol A in China	Environ. Pollut.169		2020/11/12
甲殻類	Acartia tonsa	Reproduction	EC20	4	days	37	μg/L			0 ug/L / 23 ug/L / 47 ug/L / 94 ug/L / 188 ug/L		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Daphnia magna	Survival	NOEC	14	days	0.98	mg/L			<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg		16 ECOTOX		Great Lakes Chemical Corp.	The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989	EPA/OTS 40-8998117		2020/11/12
甲殻類	Acartia tonsa	Reproduction	EC10	6	days	20	μg/L			0 ug/L / 23 ug/L / 47 ug/L / 94 ug/L / 188 ug/L		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Daphnia magna	Reproduction	MATC	21	days	0.54	mg/L			<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg		16 ECOTOX		Great Lakes Chemical Corp.	The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989	EPA/OTS 40-8998117		2020/11/12
甲殻類	Acartia tonsa	Reproduction	EC20	6	days	48	μg/L			0 ug/L / 23 ug/L / 47 ug/L / 94 ug/L / 188 ug/L		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Acartia tonsa	Reproduction	EC50	6	days	267	μg/L			0 ug/L / 23 ug/L / 47 ug/L / 94 ug/L / 188 ug/L		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Daphnia magna	Reproduction	NOEC	20	days	0.98	mg/L			<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg		16 ECOTOX		Great Lakes Chemical Corp.	The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989	EPA/OTS 40-8998117		2020/11/12
甲殻類	Daphnia magna	Reproduction	NOEC	7	days	0.98	mg/L			<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg		16 ECOTOX		Great Lakes Chemical Corp.	The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989	EPA/OTS 40-8998117		2020/11/12
甲殻類	Daphnia magna	Reproduction	NOEC	18	days	0.98	mg/L			<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg		16 ECOTOX		Great Lakes Chemical Corp.	The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989	EPA/OTS 40-8998117		2020/11/12
甲殻類	Daphnia magna	Reproduction	NOEC	15	days	0.98	mg/L			<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg		16 ECOTOX		Great Lakes Chemical Corp.	The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989	EPA/OTS 40-8998117		2020/11/12
甲殻類	Daphnia magna	Reproduction	NOEC	8	days	0.98	mg/L			<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg		16 ECOTOX		Great Lakes Chemical Corp.	The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989	EPA/OTS 40-8998117		2020/11/12
甲殻類	Daphnia magna	Reproduction(Time to first progeny)	EC10	21	days	0.084	mg/L			0 mg/L / 0 mg/L / 0.03 mg/L / 0.04 mg/L / 0.05 mg/		16 ECOTOX		Yang,S.W., Z.G. Yan, F.F. Xu, S.R. Wang, and F.C. Wu	Development of Freshwater Aquatic Life Criteria for Tetrabromobisphenol A in China	Environ. Pollut.169		2020/11/12
甲殻類	Acartia tonsa	Reproduction	EC50	4	days	135	μg/L			0 ug/L / 23 ug/L / 47 ug/L / 94 ug/L / 188 ug/L		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Daphnia magna		LOEC	21	days	0.98	mg/L					19 その他		Brominated Flame Retardants Industry Panel	The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions.	Springborn Laboratories, Inc. Report #801-2925, Study #1199-1287-6108-130. August 15, 1989.		2021/04/14
甲殻類	Daphnia magna	Reproduction	NOEC	14	days	0.98	mg/L			<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg		16 ECOTOX		Great Lakes Chemical Corp.	The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989	EPA/OTS 40-8998117		2020/11/12
甲殻類	Acartia tonsa	Reproduction	EC10	4	days	19	μg/L			0 ug/L / 23 ug/L / 47 ug/L / 94 ug/L / 188 ug/L		16 ECOTOX		Mariager,L.P.	Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean	M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark		2020/11/12
甲殻類	Daphnia magna		NOEC	21	days	0.3	mg/L					19 その他		Brominated Flame Retardants Industry Panel	The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions.	Springborn Laboratories, Inc. Report #801-2925, Study #1199-1287-6108-130. August 15, 1989.		2021/04/14
甲殻類	Mytilus edulis	Wet tissue weight	LOEC	70	days	0.126	mg/L					19 その他		[ACCBFRIP] American Chemistry Council Brominated Flame Retardant Industry Panel	Tetrabromobisphenol A: Determination of the effect on the growth of the common mussel (Mytilus edulis).	Analytical phase. Wildlife International, Ltd. Project Number: 439C-143. March 28, 2005		2021/04/14
甲殻類	Daphnia magna	Reproduction	EC10	21	days	0.139	mg/L			0 mg/L / 0 mg/L / 0.03 mg/L / 0.04 mg/L / 0.05 mg/		16 ECOTOX		Yang,S.W., Z.G. Yan, F.F. Xu, S.R. Wang, and F.C. Wu	Development of Freshwater Aquatic Life Criteria for Tetrabromobisphenol A in China	Environ. Pollut.169		2020/11/12
甲殻類	Chironomus riparius	Emergence ratio, development rate, development time	LOEC	28	days	250	mg/kg dw					19 その他		[ACCBFRIP] American Chemistry Council Brominated Flame Retardant Industry Panel	Tetrabromobisphenol-A (TBBPA): A 28-day sediment toxicity test with Chironomus riparius using spiked sediment.	Wildlife International, Ltd. Project Number: 439A-130. July 12, 2005		2021/04/14
甲殻類	Mytilus edulis	Shell length	LOEC	70	days	0.032	mg/L					19 その他		[ACCBFRIP] American Chemistry Council Brominated Flame Retardant Industry Panel	Tetrabromobisphenol A: Determination of the effect on the growth of the common mussel (Mytilus edulis).	Analytical phase. Wildlife International, Ltd. Project Number: 439C-143. March 28, 2005		2021/04/14
甲殻類	Daphnia magna	Survival	NOEC	7	days	0.98	mg/L			<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg		16 ECOTOX		Great Lakes Chemical Corp.	The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989	EPA/OTS 40-8998117		2020/11/12
甲殻類	Daphnia magna	Development//Sexual development	EC10	21	days	0.039	mg/L			0 mg/L / 0 mg/L / 0.03 mg/L / 0.04 mg/L / 0.05 mg/		16 ECOTOX		Yang,S.W., Z.G. Yan, F.F. Xu, S.R. Wang, and F.C. Wu	Development of Freshwater Aquatic Life Criteria for Tetrabromobisphenol A in China	Environ. Pollut.169		2020/11/12
魚類	Danio rerio (Zebrafish)	MortalityMortality	LOEC LOEC	5	days	0.4	mg/L [Active ingredient]				0 mg/L / 0.4 mg/L / 0.8 mg/L / 1.6 mg/L	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White	Embryonic Exposure to Tetrabromobisphenol A and Its Metabolites, Bisphenol A and Tetrabromobisphenol A Dimethyl Ether Disrupts Normal Zebrafish (Danio rerio) Development and Matrix Metalloproteinase Expression	Aquat. Toxicol.100(3)	2010
魚類	Danio rerio (Zebrafish)	PhysiologyHeart rate	LOEC LOEC	5	days	0.4	mg/L [Active ingredient]				0 mg/L / 0.4 mg/L / 0.8 mg/L / 1.6 mg/L	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White	Embryonic Exposure to Tetrabromobisphenol A and Its Metabolites, Bisphenol A and Tetrabromobisphenol A Dimethyl Ether Disrupts Normal Zebrafish (Danio rerio) Development and Matrix Metalloproteinase Expression	Aquat. Toxicol.100(3)	2010
魚類	Danio rerio (Zebrafish)	MortalityMortality	LC50 LC50	4	days	0.0000036	M [Active ingredient]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Kalasekar,S.M., E. Zacharia, N. Kessler, N.A. Ducharme, J.A. Gustafsson, I.A. Kakadiaris, and M. Bondesson	Identification of Environmental Chemicals that Induce Yolk Malabsorption in Zebrafish Using Automated Image Segmentation	Reprod. Toxicol.55	2015
魚類	Danio rerio (Zebrafish)	PhysiologyHeart rate	LOEC LOEC	48	hours	1.5	μM [Active ingredient]				0 uM / 0.75 uM / 1.5 uM / 3 uM	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White	Embryonic Exposure to Tetrabromobisphenol A and Its Metabolites, Bisphenol A and Tetrabromobisphenol A Dimethyl Ether Disrupts Normal Zebrafish (Danio rerio) Development and Matrix Metalloproteinase Expression	Aquat. Toxicol.100(3)	2010
魚類	Danio rerio (Zebrafish)	DevelopmentOrgan/tissue formation	NOEC NOEC	7	days	0.75	μM [Active ingredient]				0 uM / 0.75 uM	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White	Embryonic Exposure to Tetrabromobisphenol A and Its Metabolites, Bisphenol A and Tetrabromobisphenol A Dimethyl Ether Disrupts Normal Zebrafish (Danio rerio) Development and Matrix Metalloproteinase Expression	Aquat. Toxicol.100(3)	2010
魚類	Danio rerio (Zebrafish)	MortalityMortality		96	hours	2.64	mg/L [Active ingredient]				0 mg/L / 0.53 mg/L / 1.32 mg/L / 2.64 mg/L / 3.95 mg/L	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Chan,W.K., and K.M. Chan	Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA	Aquat. Toxicol.108	2012
魚類	Danio rerio (Zebrafish)	MortalityMortality		96	hours	1.5	mg/L [Formulation]				0 mg/L / 0.002 mg/L / 0.01 mg/L / 0.05 mg/L / 0.25 mg/L / 0.75 mg/L / 1.5 mg/L	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Hu,J., Y. Liang, M. Chen, and X. Wang	Assessing the Toxicity of TBBPA and HBCD by Zebrafish Embryo Toxicity Assay and Biomarker Analysis	Environ. Toxicol.24(4)	2009
魚類	Danio rerio (Zebrafish)	PhysiologyHeart rate	NOEC NOEC	48	hours	0.75	μM [Active ingredient]				0 uM / 0.75 uM / 1.5 uM / 3 uM	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White	Embryonic Exposure to Tetrabromobisphenol A and Its Metabolites, Bisphenol A and Tetrabromobisphenol A Dimethyl Ether Disrupts Normal Zebrafish (Danio rerio) Development and Matrix Metalloproteinase Expression	Aquat. Toxicol.100(3)	2010
魚類	Danio rerio (Zebrafish)	DevelopmentOrgan/tissue formation	NOEC NOEC	7	days	0.75	μM [Active ingredient]				0 uM / 0.75 uM	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White	Embryonic Exposure to Tetrabromobisphenol A and Its Metabolites, Bisphenol A and Tetrabromobisphenol A Dimethyl Ether Disrupts Normal Zebrafish (Danio rerio) Development and Matrix Metalloproteinase Expression	Aquat. Toxicol.100(3)	2010
魚類	Danio rerio (Zebrafish)	PhysiologyHeart rate	NOEC NOEC	72	hours	1.5	μM [Active ingredient]				0 uM / 0.75 uM / 1.5 uM / 3 uM	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White	Embryonic Exposure to Tetrabromobisphenol A and Its Metabolites, Bisphenol A and Tetrabromobisphenol A Dimethyl Ether Disrupts Normal Zebrafish (Danio rerio) Development and Matrix Metalloproteinase Expression	Aquat. Toxicol.100(3)	2010
魚類	Danio rerio (Zebrafish)	GrowthCondition index	LOEC LOEC	27	days	100	nM [Formulation]				0 nM / 10 nM / 100 nM / 1000 nM	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Riu,A., C.W. McCollum, C.L. Pinto, M. Grimaldi, A. Hillenweck, E. Perdu, D. Zalko, L. Bernard, V. Laudet, P. Balaguer,	Halogenated Bisphenol-A Analogs Act as Obesogens in Zebrafish Larvae (Danio rerio)	Toxicol. Sci.139(1)	2014
魚類	Danio rerio (Zebrafish)	DevelopmentOrgan/tissue formation	NOEC NOEC	7	days	0.75	μM [Active ingredient]				0 uM / 0.75 uM	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White	Embryonic Exposure to Tetrabromobisphenol A and Its Metabolites, Bisphenol A and Tetrabromobisphenol A Dimethyl Ether Disrupts Normal Zebrafish (Danio rerio) Development and Matrix Metalloproteinase Expression	Aquat. Toxicol.100(3)	2010
魚類	Danio rerio (Zebrafish)	MortalityMortality		96	hours	0.82	mg/L [Active ingredient]				0 mg/L / 0.11 mg/L / 0.27 mg/L / 0.55 mg/L / 0.82 mg/L	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Chan,W.K., and K.M. Chan	Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA	Aquat. Toxicol.108	2012
魚類	Danio rerio (Zebrafish)	InjuryCurvature	LOEC LOEC	5	days	0.4	mg/L [Active ingredient]				0 mg/L / 0.4 mg/L / 0.8 mg/L / 1.6 mg/L	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White	Embryonic Exposure to Tetrabromobisphenol A and Its Metabolites, Bisphenol A and Tetrabromobisphenol A Dimethyl Ether Disrupts Normal Zebrafish (Danio rerio) Development and Matrix Metalloproteinase Expression	Aquat. Toxicol.100(3)	2010
魚類	Danio rerio (Zebrafish)	PhysiologyHeart rate	LOEC LOEC	72	hours	3	μM [Active ingredient]				0 uM / 0.75 uM / 1.5 uM / 3 uM	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White	Embryonic Exposure to Tetrabromobisphenol A and Its Metabolites, Bisphenol A and Tetrabromobisphenol A Dimethyl Ether Disrupts Normal Zebrafish (Danio rerio) Development and Matrix Metalloproteinase Expression	Aquat. Toxicol.100(3)	2010
魚類	Danio rerio (Zebrafish)	DevelopmentYolk sac absorption, Yolk sac utilization	LOEC LOEC	4	days	0.000001	M [Active ingredient]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Kalasekar,S.M., E. Zacharia, N. Kessler, N.A. Ducharme, J.A. Gustafsson, I.A. Kakadiaris, and M. Bondesson	Identification of Environmental Chemicals that Induce Yolk Malabsorption in Zebrafish Using Automated Image Segmentation	Reprod. Toxicol.55	2015
魚類	Danio rerio (Zebrafish)	DevelopmentYolk sac absorption, Yolk sac utilization	LOEC LOEC	4	days	1000	nM [Active ingredient]				0 nM / 10 nM / 100 nM / 1000 nM	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Kalasekar,S.M., E. Zacharia, N. Kessler, N.A. Ducharme, J.A. Gustafsson, I.A. Kakadiaris, and M. Bondesson	Identification of Environmental Chemicals that Induce Yolk Malabsorption in Zebrafish Using Automated Image Segmentation	Reprod. Toxicol.55	2015
魚類	Danio rerio (Zebrafish)	DevelopmentDeformation	LOEC LOEC	5	days	0.4	mg/L [Active ingredient]				0 mg/L / 0.4 mg/L / 0.8 mg/L / 1.6 mg/L	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White	Embryonic Exposure to Tetrabromobisphenol A and Its Metabolites, Bisphenol A and Tetrabromobisphenol A Dimethyl Ether Disrupts Normal Zebrafish (Danio rerio) Development and Matrix Metalloproteinase Expression	Aquat. Toxicol.100(3)	2010
魚類	Danio rerio (Zebrafish)	ReproductionHatch	LOEC LOEC	5	days	0.4	mg/L [Active ingredient]				0 mg/L / 0.4 mg/L / 0.8 mg/L / 1.6 mg/L	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White	Embryonic Exposure to Tetrabromobisphenol A and Its Metabolites, Bisphenol A and Tetrabromobisphenol A Dimethyl Ether Disrupts Normal Zebrafish (Danio rerio) Development and Matrix Metalloproteinase Expression	Aquat. Toxicol.100(3)	2010
魚類	Danio rerio (Zebrafish)	DevelopmentYolk sac absorption, Yolk sac utilization	NOEC NOEC	4	days	100	nM [Active ingredient]				0 nM / 10 nM / 100 nM / 1000 nM	16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Kalasekar,S.M., E. Zacharia, N. Kessler, N.A. Ducharme, J.A. Gustafsson, I.A. Kakadiaris, and M. Bondesson	Identification of Environmental Chemicals that Induce Yolk Malabsorption in Zebrafish Using Automated Image Segmentation	Reprod. Toxicol.55	2015
魚類	Danio rerio (Zebrafish)	Survival	NOEC	8	days	0.4	mg/L			0 mg/L / 0.10 mg/L / 0.40 mg/L / 0.70 mg/L / 1.00		16 ECOTOX		Wu,S., G. Ji, J. Liu, S. Zhang, Y. Gong, and L. Shi	TBBPA Induces Developmental Toxicity, Oxidative Stress, and Apoptosis in Embryos and Zebrafish Larvae (Danio rerio)	Environ. Toxicol.31(10)		2020/11/12
魚類	Danio rerio (Zebrafish)	Mortality	LC50	162	hours	1.45	ppm			0 ppm / 1.25 ppm / 2.5 ppm / 5.0 ppm / 10 ppm / 20		16 ECOTOX		Usenko,C.Y., E.L. Abel, A. Hopkins, G. Martinez, J. Tijerina, M. Kudela, N. Norris, L. Joudeh, and E.D. Bruce	Evaluation of Common Use Brominated Flame Retardant (BFR) Toxicity Using a Zebrafish Embryo Model	Toxics4(21)		2020/11/12
魚類	Danio rerio (Zebrafish)	Behavior//Swimming	LOEC	142	hours	100	μg/L			0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Growth(Length)	NOEC	8	days	0.4	mg/L			0 mg/L / 0.10 mg/L / 0.40 mg/L / 0.70 mg/L / 1.00		16 ECOTOX		Wu,S., G. Ji, J. Liu, S. Zhang, Y. Gong, and L. Shi	TBBPA Induces Developmental Toxicity, Oxidative Stress, and Apoptosis in Embryos and Zebrafish Larvae (Danio rerio)	Environ. Toxicol.31(10)		2020/11/12
魚類	Danio rerio (Zebrafish)	Mortality	NR-ZERO	96	hours	0.82	mg/L			0 mg/L / 0.11 mg/L / 0.27 mg/L / 0.55 mg/L / 0.82		16 ECOTOX		Chan,W.K., and K.M. Chan	Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA	Aquat. Toxicol.108		2020/11/12
魚類	Danio rerio (Zebrafish)	Mortality	NR-ZERO	96	hours	2.64	mg/L			0 mg/L / 0.53 mg/L / 1.32 mg/L / 2.64 mg/L / 3.95		16 ECOTOX		Chan,W.K., and K.M. Chan	Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA	Aquat. Toxicol.108		2020/11/12
魚類	Danio rerio (Zebrafish)	Mortality	NR-LETH	96	hours	1.5	mg/L			0 mg/L / 0.002 mg/L / 0.01 mg/L / 0.05 mg/L / 0.25		16 ECOTOX		Hu,J., Y. Liang, M. Chen, and X. Wang	Assessing the Toxicity of TBBPA and HBCD by Zebrafish Embryo Toxicity Assay and Biomarker Analysis	Environ. Toxicol.24(4)		2020/11/12
魚類	Danio rerio (Zebrafish)	Survival	NOEC	142	hours	200	μg/L			0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Development//Teratogenic measurements	LOEC	8	days	0.4	mg/L			0 mg/L / 0.10 mg/L / 0.40 mg/L / 0.70 mg/L / 1.00		16 ECOTOX		Wu,S., G. Ji, J. Liu, S. Zhang, Y. Gong, and L. Shi	TBBPA Induces Developmental Toxicity, Oxidative Stress, and Apoptosis in Embryos and Zebrafish Larvae (Danio rerio)	Environ. Toxicol.31(10)		2020/11/12
魚類	Danio rerio (Zebrafish)	Mortality(Hatch)	LOEC	8	days	1	mg/L			0 mg/L / 0.10 mg/L / 0.40 mg/L / 0.70 mg/L / 1.00		16 ECOTOX		Wu,S., G. Ji, J. Liu, S. Zhang, Y. Gong, and L. Shi	TBBPA Induces Developmental Toxicity, Oxidative Stress, and Apoptosis in Embryos and Zebrafish Larvae (Danio rerio)	Environ. Toxicol.31(10)		2020/11/12
魚類	Danio rerio (Zebrafish)	Development//Abnormal	LOEC	142	hours	200	μg/L			0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Growth(Length)	LOEC	8	days	0.7	mg/L			0 mg/L / 0.10 mg/L / 0.40 mg/L / 0.70 mg/L / 1.00		16 ECOTOX		Wu,S., G. Ji, J. Liu, S. Zhang, Y. Gong, and L. Shi	TBBPA Induces Developmental Toxicity, Oxidative Stress, and Apoptosis in Embryos and Zebrafish Larvae (Danio rerio)	Environ. Toxicol.31(10)		2020/11/12
魚類	Danio rerio (Zebrafish)	Survival	LOEC	8	days	0.7	mg/L			0 mg/L / 0.10 mg/L / 0.40 mg/L / 0.70 mg/L / 1.00		16 ECOTOX		Wu,S., G. Ji, J. Liu, S. Zhang, Y. Gong, and L. Shi	TBBPA Induces Developmental Toxicity, Oxidative Stress, and Apoptosis in Embryos and Zebrafish Larvae (Danio rerio)	Environ. Toxicol.31(10)		2020/11/12
魚類	Danio rerio (Zebrafish)	Development//Teratogenic measurements	NOEC	8	days	0.1	mg/L			0 mg/L / 0.10 mg/L / 0.40 mg/L / 0.70 mg/L / 1.00		16 ECOTOX		Wu,S., G. Ji, J. Liu, S. Zhang, Y. Gong, and L. Shi	TBBPA Induces Developmental Toxicity, Oxidative Stress, and Apoptosis in Embryos and Zebrafish Larvae (Danio rerio)	Environ. Toxicol.31(10)		2020/11/12
魚類	Danio rerio (Zebrafish)	Mortality(Hatch)	NOEC	8	days	0.7	mg/L			0 mg/L / 0.10 mg/L / 0.40 mg/L / 0.70 mg/L / 1.00		16 ECOTOX		Wu,S., G. Ji, J. Liu, S. Zhang, Y. Gong, and L. Shi	TBBPA Induces Developmental Toxicity, Oxidative Stress, and Apoptosis in Embryos and Zebrafish Larvae (Danio rerio)	Environ. Toxicol.31(10)		2020/11/12
魚類	Danio rerio (Zebrafish)	Mortality(Hatch)	NOEC	142	hours	200	μg/L			0 ug/L / 200 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Mortality	LC50	72	hours	1100	μg/L			0 ug/L / 82 ug/L / 160 ug/L / 330 ug/L / 650 ug/L		16 ECOTOX		Liu,H., Z. Ma, T. Zhang, N. Yu, G. Su, J.P. Giesy, and H. Yu	Pharmacokinetics and Effects of Tetrabromobisphenol A (TBBPA) to Early Life Stages of Zebrafish (Danio rerio)	Chemosphere190		2020/11/12
魚類	Danio rerio (Zebrafish)	Behavior//Activity, general	LOEC	112	hours	5	μM			0 uM / 5 uM		16 ECOTOX		Chen,J., R.L. Tanguay, Y. Xiao, D.E. Haggard, X. Ge, Y. Jia, Y. Zheng, Q. Dong, C. Huang, and K. Lin	TBBPA Exposure During a Sensitive Developmental Window Produces Neurobehavioral Changes in Larval Zebrafish	Environ. Pollut.216		2020/11/12
魚類	Danio rerio (Zebrafish)	Behavior//Swimming	LOEC	142	hours	200	μg/L			0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Survival	NOEC	142	hours	200	μg/L			0 ug/L / 200 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Behavior//Swimming	LOEC	142	hours	100	μg/L			0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Growth(Weight)	NOEC	142	hours	200	μg/L			0 ug/L / 200 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Development//Abnormal	NOEC	142	hours	200	μg/L			0 ug/L / 200 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Development//Deformation	NOEC	162	hours	1.25	ppm			0 ppm / 1.25 ppm / 2.5 ppm / 5.0 ppm / 10 ppm / 20		16 ECOTOX		Usenko,C.Y., E.L. Abel, A. Hopkins, G. Martinez, J. Tijerina, M. Kudela, N. Norris, L. Joudeh, and E.D. Bruce	Evaluation of Common Use Brominated Flame Retardant (BFR) Toxicity Using a Zebrafish Embryo Model	Toxics4(21)		2020/11/12
魚類	Danio rerio (Zebrafish)	Mortality	NOEC	162	hours	1.25	ppm			0 ppm / 1.25 ppm / 2.5 ppm / 5.0 ppm / 10 ppm / 20		16 ECOTOX		Usenko,C.Y., E.L. Abel, A. Hopkins, G. Martinez, J. Tijerina, M. Kudela, N. Norris, L. Joudeh, and E.D. Bruce	Evaluation of Common Use Brominated Flame Retardant (BFR) Toxicity Using a Zebrafish Embryo Model	Toxics4(21)		2020/11/12
魚類	Danio rerio (Zebrafish)	Mortality	LC50	4	days	0.0000036	M					16 ECOTOX		Kalasekar,S.M., E. Zacharia, N. Kessler, N.A. Ducharme, J.A. Gustafsson, I.A. Kakadiaris, and M. Bondesson	Identification of Environmental Chemicals that Induce Yolk Malabsorption in Zebrafish Using Automated Image Segmentation	Reprod. Toxicol.55		2020/11/12
魚類	Danio rerio (Zebrafish)	Development//Deformation	NOEC	162	hours	20	ppm			0 ppm / 1.25 ppm / 2.5 ppm / 5.0 ppm / 10 ppm / 20		16 ECOTOX		Usenko,C.Y., E.L. Abel, A. Hopkins, G. Martinez, J. Tijerina, M. Kudela, N. Norris, L. Joudeh, and E.D. Bruce	Evaluation of Common Use Brominated Flame Retardant (BFR) Toxicity Using a Zebrafish Embryo Model	Toxics4(21)		2020/11/12
魚類	Danio rerio (Zebrafish)	Mortality	NR-LETH	144	hours	1.5	mg/L					16 ECOTOX		Song,M., D. Liang, Y. Liang, M. Chen, F. Wang, H. Wang, and G. Jiang	Assessing Developmental Toxicity and Estrogenic Activity of Halogenated Bisphenol A on Zebrafish (Danio rerio)	Chemosphere112		2020/11/12
魚類	Danio rerio (Zebrafish)	Survival	NOEC	21	days	1.5	mg/L			0 mg/L / 0 mg/L / 0.5 mg/L / 1.0 mg/L / 1.5 mg/L		16 ECOTOX		Song,M., D. Liang, Y. Liang, M. Chen, F. Wang, H. Wang, and G. Jiang	Assessing Developmental Toxicity and Estrogenic Activity of Halogenated Bisphenol A on Zebrafish (Danio rerio)	Chemosphere112		2020/11/12
魚類	Danio rerio (Zebrafish)	Behavior//Activity, general	NOEC	72	hours	5	μM			0 uM / 5 uM		16 ECOTOX		Chen,J., R.L. Tanguay, Y. Xiao, D.E. Haggard, X. Ge, Y. Jia, Y. Zheng, Q. Dong, C. Huang, and K. Lin	TBBPA Exposure During a Sensitive Developmental Window Produces Neurobehavioral Changes in Larval Zebrafish	Environ. Pollut.216		2020/11/12
魚類	Danio rerio (Zebrafish)	Behavior//Swimming	NOEC	142	hours	200	μg/L			0 ug/L / 200 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Behavior//Swimming	NOEC	142	hours	200	μg/L			0 ug/L / 200 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Development//Abnormal	NOEC	142	hours	200	μg/L			0 ug/L / 200 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Mortality(Hatch)	NOEC	142	hours	200	μg/L			0 ug/L / 200 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Survival	NOEC	142	hours	200	μg/L			0 ug/L / 200 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Physiology//Heart rate	NOEC	48	hours	100	μg/L			0 ug/L / 1.0 ug/L / 10 ug/L / 100 ug/L / 1000 ug/L		16 ECOTOX		Carlsson,G., and L. Norrgren	Comparison of Embryo Toxicity Using Two Classes of Aquatic Vertebrates	Environ. Toxicol. Pharmacol.37		2020/11/12
魚類	Danio rerio (Zebrafish)	Growth(Weight)	NOEC	142	hours	200	μg/L			0 ug/L / 200 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Behavior//Swimming	LOEC	142	hours	200	μg/L			0 ug/L / 200 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Mortality	LOEC	144	hours	0.5	mg/L					16 ECOTOX		Song,M., D. Liang, Y. Liang, M. Chen, F. Wang, H. Wang, and G. Jiang	Assessing Developmental Toxicity and Estrogenic Activity of Halogenated Bisphenol A on Zebrafish (Danio rerio)	Chemosphere112		2020/11/12
魚類	Danio rerio (Zebrafish)	Physiology//Heart rate	LOEC	48	hours	1000	μg/L			0 ug/L / 1.0 ug/L / 10 ug/L / 100 ug/L / 1000 ug/L		16 ECOTOX		Carlsson,G., and L. Norrgren	Comparison of Embryo Toxicity Using Two Classes of Aquatic Vertebrates	Environ. Toxicol. Pharmacol.37		2020/11/12
魚類	Danio rerio (Zebrafish)	Mortality	LOEC	48	hours	1000	μg/L			0 ug/L / 1.0 ug/L / 10 ug/L / 100 ug/L / 1000 ug/L		16 ECOTOX		Carlsson,G., and L. Norrgren	Comparison of Embryo Toxicity Using Two Classes of Aquatic Vertebrates	Environ. Toxicol. Pharmacol.37		2020/11/12
魚類	Danio rerio (Zebrafish)	Physiology//Blood flow	LOEC	48	hours	1000	μg/L			0 ug/L / 1.0 ug/L / 10 ug/L / 100 ug/L / 1000 ug/L		16 ECOTOX		Carlsson,G., and L. Norrgren	Comparison of Embryo Toxicity Using Two Classes of Aquatic Vertebrates	Environ. Toxicol. Pharmacol.37		2020/11/12
魚類	Danio rerio (Zebrafish)	Development//Deformation	LOEC	162	hours	2.5	ppm			0 ppm / 1.25 ppm / 2.5 ppm / 5.0 ppm / 10 ppm / 20		16 ECOTOX		Usenko,C.Y., E.L. Abel, A. Hopkins, G. Martinez, J. Tijerina, M. Kudela, N. Norris, L. Joudeh, and E.D. Bruce	Evaluation of Common Use Brominated Flame Retardant (BFR) Toxicity Using a Zebrafish Embryo Model	Toxics4(21)		2020/11/12
魚類	Danio rerio (Zebrafish)	Behavior//Swimming	LOEC	142	hours	200	μg/L			0 ug/L / 200 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Behavior//Swimming	LOEC	142	hours	200	μg/L			0 ug/L / 200 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Mortality	LOEC	162	hours	2.5	ppm			0 ppm / 1.25 ppm / 2.5 ppm / 5.0 ppm / 10 ppm / 20		16 ECOTOX		Usenko,C.Y., E.L. Abel, A. Hopkins, G. Martinez, J. Tijerina, M. Kudela, N. Norris, L. Joudeh, and E.D. Bruce	Evaluation of Common Use Brominated Flame Retardant (BFR) Toxicity Using a Zebrafish Embryo Model	Toxics4(21)		2020/11/12
魚類	Danio rerio (Zebrafish)	Behavior//Swimming	NOEC	142	hours	200	μg/L			0 ug/L / 200 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Behavior//Swimming	NOEC	72	hours	5	μM			0 uM / 5 uM		16 ECOTOX		Chen,J., R.L. Tanguay, Y. Xiao, D.E. Haggard, X. Ge, Y. Jia, Y. Zheng, Q. Dong, C. Huang, and K. Lin	TBBPA Exposure During a Sensitive Developmental Window Produces Neurobehavioral Changes in Larval Zebrafish	Environ. Pollut.216		2020/11/12
魚類	Danio rerio (Zebrafish)	Behavior//Distance moved, change in direct movement	NOEL		hours	3.8	μM			0 uM / 0 uM / 0 uM / 1.2 uM / 2.1 uM / 3.8 uM / 6.		16 ECOTOX		Jarema,K.A., D.L. Hunter, R.M. Shaffer, M. Behl, and S. Padilla	Acute and Developmental Behavioral Effects of Flame Retardants and Related Chemicals in Zebrafish	Neurotoxicol. Teratol.52		2020/11/12
魚類	Danio rerio (Zebrafish)	Behavior//Swimming	NOEC	142	hours	50	μg/L			0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Mortality(Hatch)	NOEC	142	hours	400	μg/L			0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Development//Abnormal	NOEC	142	hours	100	μg/L			0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Behavior//Swimming	NOEC	112	hours	5	μM			0 uM / 5 uM		16 ECOTOX		Chen,J., R.L. Tanguay, Y. Xiao, D.E. Haggard, X. Ge, Y. Jia, Y. Zheng, Q. Dong, C. Huang, and K. Lin	TBBPA Exposure During a Sensitive Developmental Window Produces Neurobehavioral Changes in Larval Zebrafish	Environ. Pollut.216		2020/11/12
魚類	Danio rerio (Zebrafish)	Growth(Weight)	NOEC	142	hours	400	μg/L			0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Behavior//Swimming	NOEC	142	hours	50	μg/L			0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Survival	LOEC	142	hours	400	μg/L			0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)	Physiology//Blood flow	NOEC	48	hours	100	μg/L			0 ug/L / 1.0 ug/L / 10 ug/L / 100 ug/L / 1000 ug/L		16 ECOTOX		Carlsson,G., and L. Norrgren	Comparison of Embryo Toxicity Using Two Classes of Aquatic Vertebrates	Environ. Toxicol. Pharmacol.37		2020/11/12
魚類	Danio rerio (Zebrafish)	Development//Slowed, Retarded, Delayed or Non-development	EC50	72	hours	1600	μg/L			0 ug/L / 82 ug/L / 160 ug/L / 330 ug/L / 650 ug/L		16 ECOTOX		Liu,H., Z. Ma, T. Zhang, N. Yu, G. Su, J.P. Giesy, and H. Yu	Pharmacokinetics and Effects of Tetrabromobisphenol A (TBBPA) to Early Life Stages of Zebrafish (Danio rerio)	Chemosphere190		2020/11/12
魚類	Danio rerio (Zebrafish)	Mortality	NOEC	48	hours	100	μg/L			0 ug/L / 1.0 ug/L / 10 ug/L / 100 ug/L / 1000 ug/L		16 ECOTOX		Carlsson,G., and L. Norrgren	Comparison of Embryo Toxicity Using Two Classes of Aquatic Vertebrates	Environ. Toxicol. Pharmacol.37		2020/11/12
魚類	Danio rerio (Zebrafish)	Morphology//Length	LOEC	40	hours	5	μM			0 uM / 5 uM		16 ECOTOX		Chen,J., R.L. Tanguay, Y. Xiao, D.E. Haggard, X. Ge, Y. Jia, Y. Zheng, Q. Dong, C. Huang, and K. Lin	TBBPA Exposure During a Sensitive Developmental Window Produces Neurobehavioral Changes in Larval Zebrafish	Environ. Pollut.216		2020/11/12
魚類	Danio rerio (Zebrafish)	Mortality	LC50	144	hours	1.24	mg/L					16 ECOTOX		Song,M., D. Liang, Y. Liang, M. Chen, F. Wang, H. Wang, and G. Jiang	Assessing Developmental Toxicity and Estrogenic Activity of Halogenated Bisphenol A on Zebrafish (Danio rerio)	Chemosphere112		2020/11/12
魚類	Danio rerio (Zebrafish)	Behavior//Swimming	NOEC	142	hours	100	μg/L			0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L		16 ECOTOX		Zhu,B., G. Zhao, L. Yang, and B. Zhou	Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae	Chemosphere197		2020/11/12
魚類	Danio rerio (Zebrafish)								×	0 (control), 0.023, 0.047, 0.094, 0.188, 0.375, 0.750, 1.50, 3.00, 6.00 µM		12 ECHA Information on Registered Substances	2	Kuiper RV, van den Brandhof EJ, Leonards PEG, van der Ven LTM, Wester PW & Vos JG	Toxicity of Tetrabromobisphenol A (TBBPA) in zebrafish (Danio rerio) in a partial life-cycle test	Arch. Toxicol. 81	2007
魚類	Pimephales promelas (Fathead minnow)	mortality	NOEC	144	hours	0.26	mg/L		○	0.18, 0.27, 0.42, 0. 63, 1.0 mg/L	0.19, 0.26, 0.32, 0.45, 0.63 mg/L	12 ECHA Information on Registered Substances	2		study report		1988	2020/03/18
魚類	Pimephales promelas (Fathead minnow)	mortality	LC50	144	hours	0.49	mg/L		○	0.18, 0.27, 0.42, 0. 63, 1.0 mg/L	0.19, 0.26, 0.32, 0.45, 0.63 mg/L	12 ECHA Information on Registered Substances	2		study report		1988	2020/03/18
魚類	Danio rerio (Zebrafish)	Growth	NOEC	7	days	0.75	μM					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White	Embryonic Exposure to Tetrabromobisphenol A and Its Metabolites, Bisphenol A and Tetrabromobisphenol A Dimethyl Ether Disrupts Normal Zebrafish (Danio rerio) Development and Matrix Metalloproteinase Expression	Aquat. Toxicol.100(3): 255-262	2010	2016/03/25
魚類	Danio rerio (Zebrafish)	Biochemical	NOEC	4	days	10	μg/L					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Hu,J., Y. Liang, M. Chen, and X. Wang	Assessing the Toxicity of TBBPA and HBCD by Zebrafish Embryo Toxicity Assay and Biomarker Analysis	Environ. Toxicol.24(4): 334-342	2009	2016/03/25
魚類	Oncorhynchus mykiss (Rainbow trout)	Biochemical				50	その他others [mg/kg bdwt]					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Christiansen,L.B., K.L. Pedersen, S.N. Pedersen, B. Korsgaard, and P. Bjerregaard	In Vivo Comparison of Xenoestrogens Using Rainbow Trout Vitellogenin Induction as a Screening System	Environ. Toxicol. Chem.19(7): 1867-1874	2000	2016/03/25
魚類	Danio rerio (Zebrafish)	Biochemical	NOEC	4	days	10	μg/L					16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)		Hu,J., Y. Liang, M. Chen, and X. Wang	Assessing the Toxicity of TBBPA and HBCD by Zebrafish Embryo Toxicity Assay and Biomarker Analysis	Environ. Toxicol.24(4): 334-342	2009	2016/03/25

生物種

学名

影響内容

エンドポイント

暴露期間(値)

暴露期間(単位)

毒性値

毒性値(単位)

Read-across *

QSAR

GLP

設定濃度

実測濃度

情報源

情報源による信頼性評価

著者

タイトル

記載誌

発行年

情報更新日

subject type

scientific name

effect

endpoint

exposure duration value

exposure duration unit

toxicity value

toxicity unit

Read-across

QSAR

GLP

nominal concentration

measured concentration

original work type

original work reliability rank

author

title

referenced journal

publication year

Information update date

藻類

Skeletonema costatum

TBBPA was toxic to S. costatum below the estimated saturation concentration (1.5 mg/litre)

12 ECHA Information on Registered Substances

Walsh and Alexander

A marine algal bioassay method: Results with pesticides and industrial wastes

Water Air Soil Pollut. 13

2021/03/02

藻類

Chlorella sp.

Chlorella sp. was not inhibited by as much as 50 % by 1.5 mg/L TBBPA

12 ECHA Information on Registered Substances

Walsh GE, Yoder MJ, McLaughlin LL & Lores EM

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotox. Environ. Safe 14

2021/03/02

藻類

Chlorella sp.

0.05 mL test material in nanograde acetone and 51 mL growth medium with algae

12 ECHA Information on Registered Substances

Walsh and Alexander

A marine algal bioassay method: Results with pesticides and industrial wastes

Water Air Soil Pollut. 13

1980

藻類

Thalassiosira pseudonana

0.05 mL test material in nanograde acetone and 51 mL growth medium with algae

12 ECHA Information on Registered Substances

Walsh GE, Yoder MJ, McLaughlin LL & Lores EM

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotox. Environ. Safe 14

1987

藻類

Skeletonema costatum

0.05 mL test material in nanograde acetone and 51 mL growth medium with algae

12 ECHA Information on Registered Substances

Walsh GE, Yoder MJ, McLaughlin LL & Lores EM

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotox. Environ. Safe 14

1987

藻類

Pseudokirchneriella subcapitata

Population

LOEC

days

9.2

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise

Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays

Chemosphere85(1): 50-55

2011

2016/03/25

藻類

Pseudokirchneriella subcapitata

Population

LOEC

days

9.2

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise

Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays

Chemosphere85(1): 50-55

2011

2016/03/25

藻類

Pseudokirchneriella subcapitata

Population

LOEC

days

9.2

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise

Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays

Chemosphere85(1): 50-55

2011

2016/03/25

藻類

Pseudokirchneriella subcapitata

Population

LOEC

days

9.2

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise

Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays

Chemosphere85(1): 50-55

2011

2016/03/25

藻類

Pseudokirchneriella subcapitata

Population

NOEC

days

4.8

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise

Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays

Chemosphere85(1): 50-55

2011

2016/03/25

藻類

Pseudokirchneriella subcapitata

Population

NOEC

days

4.8

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise

Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays

Chemosphere85(1): 50-55

2011

2016/03/25

藻類

Pseudokirchneriella subcapitata

Population

NOEC

days

4.8

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise

Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays

Chemosphere85(1): 50-55

2011

2016/03/25

藻類

Pseudokirchneriella subcapitata

Population

NOEC

days

4.8

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise

Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays

Chemosphere85(1): 50-55

2011

2016/03/25

藻類

Selenastrum capricornutum

成長曲線下面積

EbC50

hours

7.08

mg/L

○

対照区,　助剤対照区,　0.50, 1.05, 2.20, 4.60, 9.55, 20.0mg/l

0 hour : 0.59, 1.25, 2.54, 4.26, 9.02, 19.0mg/l　　　72 hour : 0.35, 0.77, 1.55, 2.77, 6.09, 13.3mg/l　　　

1 日本環境省　生態リスク初期評価

2020/01/08

藻類

Skeletonema costatum

Growth rate

EC50

hours

0.89

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.

Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.

Environ. Safety, 14

1987

2020/01/07

藻類

Chlorella sp.

Growth rate

EC50

hours

>1.5

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.

Responses of marine unicellular algae to brominated organic compounds in six growth media.

Ecotox. Environ. Safety, 14

1987

2020/01/07

藻類

Chlorella sp.

Growth rate

EC50

hours

>1.5

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.

Responses of marine unicellular algae to brominated organic compounds in six growth media.

Ecotox. Environ. Safety, 14

1987

2020/01/07

藻類

Chlorella sp.

Growth rate

EC50

hours

>1.5

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.

Responses of marine unicellular algae to brominated organic compounds in six growth media.

Ecotox. Environ. Safety, 14

1987

2020/01/07

藻類

Chlorella sp.

Growth rate

EC50

hours

>1.5

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.

Responses of marine unicellular algae to brominated organic compounds in six growth media.

Ecotox. Environ. Safety, 14

1987

2020/01/07

藻類

Chlorella sp.

Growth rate

EC50

hours

>=1.5

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.

Responses of marine unicellular algae to brominated organic compounds in six growth media.

Ecotox. Environ. Safety, 14

1987

2020/01/07

藻類

Pseudokirchneriella subcapitata

成長曲線下面積

EbC50

hours

1.53

mg/L

○

対照区,　助剤対照区,　0.570, 1.00, 1.80, 3.20, 5.70mg/l

0.153, 0.268, 0.497, 0.919, 1.88mg/l

1 日本環境省　生態リスク初期評価

2020/01/10

藻類

Thalassiosira pseudonana

Growth rate

EC50

hours

0.83

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.

Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.

Environ. Safety, 14

1987

2020/01/07

藻類

Selenastrum capricornutum

成長速度

ErC50

hours

9.46

mg/L

○

対照区,　助剤対照区,　0.50, 1.05, 2.20, 4.60, 9.55, 20.0mg/l

0 hour : 0.59, 1.25, 2.54, 4.26, 9.02, 19.0mg/l　　　72 hour : 0.35, 0.77, 1.55, 2.77, 6.09, 13.3mg/l　　　

1 日本環境省　生態リスク初期評価

2020/01/08

藻類

Chlorella sp.

Growth rate

EC50

hours

>1.5

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.

Responses of marine unicellular algae to brominated organic compounds in six growth media.

Ecotox. Environ. Safety, 14

1987

2020/01/07

藻類

Skeletonema costatum

Growth rate

EC50

hours

0.55

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.

Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.

Environ. Safety, 14

1987

2020/01/07

藻類

Skeletonema costatum

Growth rate

EC50

hours

0.09

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.

Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.

Environ. Safety, 14

1987

2020/01/07

藻類

Skeletonema costatum

Growth rate

EC50

hours

0.49

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.

Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.

Environ. Safety, 14

1987

2020/01/07

藻類

Skeletonema costatum

Growth rate

EC50

hours

0.14

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.

Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.

Environ. Safety, 14

1987

2020/01/07

藻類

Selenastrum capricornutum

Cell density

EC50

hours

>5600

μg/L

○

340, 760, 1500, 3000, 5600µg TBBPA/l

14 BUA Report

Great Lakes Chemical Corporation

Toxicity of tetrabromobisphenol A to the freshwater green alga Selenastrum capricornutum. Springborn Laboratories, Report No: 88-10-2828

1988

2020/01/22

藻類

Skeletonema costatum

EC50

hours

0.09～0.89

mg/L

4 OECD SIDS (HPVC)

2020/01/17

藻類

Pseudokirchneriella subcapitata

EC50

hours

>5.6

mg/L

4 OECD SIDS (HPVC)

2020/01/17

藻類

Pseudokirchneriella subcapitata

成長速度

ErC50

hours

>1.88

mg/L

○

対照区,　助剤対照区,　0.570, 1.00, 1.80, 3.20, 5.70mg/l

0.153, 0.268, 0.497, 0.919, 1.88mg/l

1 日本環境省　生態リスク初期評価

2020/01/10

藻類

Thalassiosira pseudonana

Growth rate

EC50

hours

0.21

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.

Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.

Environ. Safety, 14

1987

2020/01/07

藻類

Chlorella sp.

EC50

hours

>1500

μg/L

14 BUA Report

Walsh G, Yoder M, McLaughlin L, Lores E

Responses of marine unicellular algae to brominated organic compounds in six growth media.

Ecotox Environ Saf 14

1987

2020/01/21

藻類

Thalassiosira pseudonana

EC50

hours

130～1000

μg/L

14 BUA Report

Walsh G, Yoder M, McLaughlin L, Lores E

Responses of marine unicellular algae to brominated organic compounds in six growth media.

Ecotox Environ Saf 14

1987

2020/01/21

藻類

Skeletonema costatum

EC50

hours

90～890

μg/L

14 BUA Report

Walsh G, Yoder M, McLaughlin L, Lores E

Responses of marine unicellular algae to brominated organic compounds in six growth media.

Ecotox Environ Saf 14

1987

2020/01/21

藻類

Thalassiosira pseudonana

Growth rate

EC50

hours

0.31

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.

Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.

Environ. Safety, 14

1987

2020/01/07

藻類

Thalassiosira pseudonana

Growth rate

EC50

hours

0.13

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.

Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.

Environ. Safety, 14

1987

2020/01/07

藻類

Pseudokirchneriella subcapitata

収量

EyC50

hours

1.57

mg/L

○

対照区,　助剤対照区,　0.570, 1.00, 1.80, 3.20, 5.70mg/l

0.153, 0.268, 0.497, 0.919, 1.88mg/l

1 日本環境省　生態リスク初期評価

2020/01/10

藻類

Thalassiosira pseudonana

Growth rate

EC50

hours

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.

Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.

Environ. Safety, 14

1987

2020/01/07

藻類

Thalassiosira pseudonana

Growth rate

EC50

hours

0.17

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Walsh G. E., Yoder M. J., McLaughlin L. L. and Lores E. M.

Responses of marine unicellular algae to brominated organic compounds in six growth media. Ecotox.

Environ. Safety, 14

1987

2020/01/07

藻類

Selenastrum capricornutum

Biomass

EC50

days

7080

μg/L

6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）

環境庁

平成11年度　生態影響試験実施事業報告

2000

2020/02/14

藻類

Pseudokirchneriella subcapitata

Cell density (biomass)

EC50

hours

>5.6

mg/L

0.34, 0.76, 1.5, 3.0, 5.6mg/l, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Life Sciences

Toxicity of tetrabromobisphenol A to the freshwater green alga Selenastrum capricornutum.

Report No 88-10-2828. Springborn Life Sciences, Inc., Wareham, Massachusetts

1988

2019/12/27

藻類

Pseudokirchneriella subcapitata

Growth rate

ErC50

hours

9.48

mg/L

0, 0.50, 1.05, 2.20, 4.60, 9.55, 20.0mg/l

0, 0.45, 0.98, 1.98, 3.44, 7.41, 15.9mg/l 設定値の93～119％（0h)、60～73％（72h)

18 既存化学物質安全性(ハザード)評価シート

環境省

既存化学物質審査シート（三監No.10）

2020/01/08

藻類

Pseudokirchneriella subcapitata

Cell density (biomass)

EC50

hours

>5.6

mg/L

0.34, 0.76, 1.5, 3.0, 5.6mg/l, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Life Sciences

Toxicity of tetrabromobisphenol A to the freshwater green alga Selenastrum capricornutum.

Report No 88-10-2828. Springborn Life Sciences, Inc., Wareham, Massachusetts

1988

2019/12/27

藻類

Thalassiosira pseudonana

PopulationPopulation change (change in N/change in time)

EC50 EC50

hours

140

μg/L [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotoxicol. Environ. Saf.14

1987

藻類

Skeletonema costatum

PopulationPopulation change (change in N/change in time)

EC50 EC50

hours

560

μg/L [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotoxicol. Environ. Saf.14

1987

藻類

Thalassiosira pseudonana

PopulationPopulation change (change in N/change in time)

EC50 EC50

hours

820

μg/L [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotoxicol. Environ. Saf.14

1987

藻類

Thalassiosira pseudonana

PopulationPopulation change (change in N/change in time)

EC50 EC50

hours

1000

μg/L [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotoxicol. Environ. Saf.14

1987

藻類

Thalassiosira pseudonana

PopulationPopulation change (change in N/change in time)

EC50 EC50

hours

350

μg/L [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotoxicol. Environ. Saf.14

1987

藻類

Skeletonema costatum

PopulationPopulation change (change in N/change in time)

EC50 EC50

hours

550

μg/L [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotoxicol. Environ. Saf.14

1987

藻類

Skeletonema costatum

PopulationPopulation change (change in N/change in time)

EC50 EC50

hours

410

μg/L [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotoxicol. Environ. Saf.14

1987

藻類

Thalassiosira pseudonana

PopulationPopulation change (change in N/change in time)

EC50 EC50

hours

220

μg/L [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotoxicol. Environ. Saf.14

1987

藻類

Skeletonema costatum

PopulationPopulation change (change in N/change in time)

EC50 EC50

hours

140

μg/L [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotoxicol. Environ. Saf.14

1987

藻類

Thalassiosira pseudonana

PopulationPopulation change (change in N/change in time)

EC50 EC50

hours

110

μg/L [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotoxicol. Environ. Saf.14

1987

藻類

Thalassiosira pseudonana

PopulationPopulation change (change in N/change in time)

EC50 EC50

hours

260

μg/L [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotoxicol. Environ. Saf.14

1987

藻類

Thalassiosira pseudonana

PopulationPopulation change (change in N/change in time)

EC50 EC50

hours

170

μg/L [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotoxicol. Environ. Saf.14

1987

藻類

Skeletonema costatum

PopulationPopulation change (change in N/change in time)

EC50 EC50

hours

μg/L [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotoxicol. Environ. Saf.14

1987

藻類

Thalassiosira pseudonana

PopulationPopulation change (change in N/change in time)

EC50 EC50

hours

190

μg/L [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotoxicol. Environ. Saf.14

1987

藻類

Skeletonema costatum

PopulationPopulation change (change in N/change in time)

EC50 EC50

hours

640

μg/L [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotoxicol. Environ. Saf.14

1987

藻類

Skeletonema costatum

PopulationPopulation change (change in N/change in time)

EC50 EC50

hours

1140

μg/L [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotoxicol. Environ. Saf.14

1987

藻類

Skeletonema costatum

PopulationPopulation change (change in N/change in time)

EC50 EC50

hours

540

μg/L [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotoxicol. Environ. Saf.14

1987

藻類

Thalassiosira pseudonana

PopulationPopulation change (change in N/change in time)

EC50 EC50

hours

160

μg/L [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotoxicol. Environ. Saf.14

1987

藻類

Thalassiosira pseudonana

PopulationPopulation change (change in N/change in time)

EC50 EC50

hours

840

μg/L [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotoxicol. Environ. Saf.14

1987

藻類

Skeletonema costatum

PopulationPopulation change (change in N/change in time)

EC50 EC50

hours

μg/L [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Walsh,G.E., M.J. Yoder, L.L. McLaughlin, and E.M. Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media

Ecotoxicol. Environ. Saf.14

1987

藻類

Pseudokirchneriella subcapitata

EC50

hours

>1.9

mg/L

1 日本環境省　生態リスク初期評価

環境省

（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）

2016/11/09

藻類

Pseudokirchneriella subcapitata

EC50

hours

9.5

mg/L

1 日本環境省　生態リスク初期評価

環境省

（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）

2016/11/09

藻類

Pseudokirchneriella subcapitata

EC50

hours

7.1

mg/L

1 日本環境省　生態リスク初期評価

環境省

（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）

2016/11/09

藻類

Pseudokirchneriella subcapitata

EC50

hours

1.5

mg/L

1 日本環境省　生態リスク初期評価

環境省

（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）

2016/11/09

藻類

Pseudokirchneriella subcapitata

生長阻害

EbC50

hours

1.53

mg/L

11 Japan チャレンジプログラム

2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験

A050386

2016/03/08

藻類

Selenastrum capricornutum

生長阻害

EbC50

hours

3.1

mg/L

11 Japan チャレンジプログラム

2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験

EAI95005

2016/03/08

藻類

Pseudokirchneriella subcapitata

biomass

EC50

hours

>5.6

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Life Sciences

Toxicity of tetrabromobisphenol A to the freshwater green alga Selenastrum capricornutum.

Report No 88-10-2828. Springborn Life Sciences, Inc., Wareham, Massachusetts.

1988

2016/03/04

藻類

Selenastrum capricornutum

生長阻害　24-48h

ErC50

hours

5.8

mg/L

11 Japan チャレンジプログラム

2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験

EAI95005

2016/03/08

藻類

Pseudokirchneriella subcapitata

生長阻害

EyC50

hours

1.57

mg/L

11 Japan チャレンジプログラム

2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験

A050386

2016/03/08

藻類

Pseudokirchneriella subcapitata

生長阻害

ErC50

hours

>1.88

mg/L

11 Japan チャレンジプログラム

2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験

A050386

2016/03/08

藻類

Selenastrum capricornutum

生長阻害　24-72h

ErC50

hours

13.6

mg/L

11 Japan チャレンジプログラム

4，4’一イソプロピリデンビス（2，6一ジブロモフェノール）の藻類（Selenastrum capricornutum)に対する生長阻害試験

9B434G

2016/03/08

藻類

Pseudokirchneriella subcapitata

biomass

EC50

hours

>5.6

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Life Sciences

Toxicity of tetrabromobisphenol A to the freshwater green alga Selenastrum capricornutum.

Report No 88-10-2828. Springborn Life Sciences, Inc., Wareham, Massachusetts.

1988

2016/03/04

藻類

Chlorella sp.

population growth

days

1500

μg/L

6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）

Walsh,G.E., M.J.Yoder, L.L.McLaughlin, and E.M.Lores

Responses of Marine Unicellular Algae to Brominated Organic Compounds in Six Growth Media.

Ecotoxicol. Environ. Saf.

1987

2016/03/04

藻類

Selenastrum capricornutum

Biomass

EC50

days

7080

μg/L

6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）

環境庁

平成 11 年度　生態影響試験実施事業報告

2000

2016/03/05

藻類

Selenastrum capricornutum

生長阻害　24-48h

ErC50

hours

13.2

mg/L

11 Japan チャレンジプログラム

4，4’一イソプロピリデンビス（2，6一ジブロモフェノール）の藻類（Selenastrum capricornutum)に対する生長阻害試験

9B434G

2016/03/08

藻類

Selenastrum capricornutum

生長阻害

EbC50

hours

7.08

mg/L

11 Japan チャレンジプログラム

4，4’一イソプロピリデンビス（2，6一ジブロモフェノール）の藻類（Selenastrum capricornutum)に対する生長阻害試験

9B434G

2016/03/08

藻類

Selenastrum capricornutum

生長阻害　24-72h

ErC50

hours

4.3

mg/L

11 Japan チャレンジプログラム

2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験

EAI95005

2016/03/08

藻類

Pseudokirchneriella subcapitata

EC50

hours

>5.6

mg/L

4 OECD SIDS (HPVC)

2016/02/19

藻類

Pseudokirchneriella subcapitata

EC50

hours

>5.6

mg/L

4 OECD SIDS (HPVC)

2016/02/19

藻類

Skeletonema costatum

Population size reduction

EC50

days

μg/L

6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）

2-（ジメチルアミノ）エチルメタクリレートのオオミジンコ（Daphnia magna)に対する急性遊泳阻害試験

N01997-生16

2020/02/14

藻類

Chlorella sp.

Population growth

days

1500

μg/L

6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）

2-（ジメチルアミノ）エチルメタクリレートのオオミジンコ（Daphnia magna)に対する繁殖阻害試験

N01997-生17

2020/02/14

藻類

Scenedesmus obliquus

EC50

days

>0.4

mg/L

19 その他

Peng FQ, Ying GG, Yang B, Liu YS, Lai HJ, Zhou GJ, Chen J and Zhao JL

Biotransformation of the flame retardant tetrabromobisphenol‐A (TBBPA) by freshwater microalgae

Environmental Toxicology and Chemistry, 33

2021/05/14

藻類

Scenedesmus acuminatus

EC50

days

>0.4

mg/L

19 その他

Peng FQ, Ying GG, Yang B, Liu YS, Lai HJ, Zhou GJ, Chen J and Zhao JL

Biotransformation of the flame retardant tetrabromobisphenol‐A (TBBPA) by freshwater microalgae

Environmental Toxicology and Chemistry, 33

2021/05/14

藻類

Pseudokirchneriella subcapitata

EC50

days

>0.4

mg/L

19 その他

Peng FQ, Ying GG, Yang B, Liu YS, Lai HJ, Zhou GJ, Chen J and Zhao JL

Biotransformation of the flame retardant tetrabromobisphenol‐A (TBBPA) by freshwater microalgae

Environmental Toxicology and Chemistry, 33

2021/04/14

藻類

Scenedesmus quadricauda

cell number

EC50

hours

1.202

mg/L

0 mg/L / 0 mg/L / 0.4 mg/L / 0.56 mg/L / 0.784 mg/

16 ECOTOX

Yang,S.W., Z.G. Yan, F.F. Xu, S.R. Wang, and F.C. Wu

Development of Freshwater Aquatic Life Criteria for Tetrabromobisphenol A in China

Environ. Pollut.169

2020/11/12

藻類

Pseudokirchneriella subcapitata

Chlorophyll

EC50

hours

14.2

μmol/L

0 umol/L / 1.8 umol/L / 4.8 umol/L / 9.2 umol/L /

16 ECOTOX

Debenest,T., F. Gagne, A.N. Petit, M. Kohli, P. Eullafroy, and C. Blaise

Monitoring of a Flame Retardant (Tetrabromobisphenol A) Toxicity on Different Microalgae Assessed by Flow Cytometry

J. Environ. Monit.12(10)

2020/11/12

藻類

Chlorella pyrenoidosa

EC50

days

>0.4

mg/L

19 その他

Peng FQ, Ying GG, Yang B, Liu YS, Lai HJ, Zhou GJ, Chen J and Zhao JL

Biotransformation of the flame retardant tetrabromobisphenol‐A (TBBPA) by freshwater microalgae

Environmental Toxicology and Chemistry, 33

2021/04/14

藻類

Scenedesmus quadricauda

EC50

days

>0.4

mg/L

19 その他

Peng FQ, Ying GG, Yang B, Liu YS, Lai HJ, Zhou GJ, Chen J and Zhao JL

Biotransformation of the flame retardant tetrabromobisphenol‐A (TBBPA) by freshwater microalgae

Environmental Toxicology and Chemistry, 33

2021/05/14

藻類

Selenastrum capricornutum

Growth

EC50

hours

>5.6

mg/L

0.34-5.6 mg/L

19 その他

IPCS

Environmental health criteria 172, Tetrabromobisphenol A and derivatives

Geneva, World Health Organization

2021/04/13

藻類

Chlorella sp.

Growth

EC50

hours

>1500

μg/L

19 その他

IPCS

Environmental health criteria 172, Tetrabromobisphenol A and derivatives

Geneva, World Health Organization

2021/04/13

藻類

Thalassiosira pseudonana

EC50

hours

130～1000

μg/L

19 その他

IPCS

Environmental health criteria 172, Tetrabromobisphenol A and derivatives

Geneva, World Health Organization

2021/04/13

藻類

Skeletonema costatum

EC50

hours

90～890

μg/L

19 その他

IPCS

Environmental health criteria 172, Tetrabromobisphenol A and derivatives

Geneva, World Health Organization

2021/04/13

藻類

Pseudokirchneriella subcapitata

成長曲線下面積

NOEbC

hours

0.268

mg/L

○

対照区,　助剤対照区,　0.570, 1.00, 1.80, 3.20, 5.70mg/l

0.153, 0.268, 0.497, 0.919, 1.88mg/l

1 日本環境省　生態リスク初期評価

2020/01/10

藻類

Pseudokirchneriella subcapitata

Growth rate

NOEC

hours

1.98

mg/L

0, 0.50, 1.05, 2.20, 4.60, 9.55, 20.0mg/l

0, 0.45, 0.98, 1.98, 3.44, 7.41, 15.9mg/l 設定値の93～119％（0h)、60～73％（72h)

18 既存化学物質安全性(ハザード)評価シート

環境省

既存化学物質審査シート（三監No.10）

2020/01/08

藻類

Selenastrum capricornutum

成長曲線下面積

NOEbC

hours

4.6

mg/L

○

対照区,　助剤対照区,　0.50, 1.05, 2.20, 4.60, 9.55, 20.0mg/l

0 hour : 0.59, 1.25, 2.54, 4.26, 9.02, 19.0mg/l　　　72 hour : 0.35, 0.77, 1.55, 2.77, 6.09, 13.3mg/l　　　

1 日本環境省　生態リスク初期評価

2020/01/08

藻類

Selenastrum capricornutum

成長速度

NOEC

hours

3.44

mg/L

○

対照区,　助剤対照区,　0.50, 1.05, 2.20, 4.60, 9.55, 20.0mg/l

0 hour : 0.59, 1.25, 2.54, 4.26, 9.02, 19.0mg/l　　　72 hour : 0.35, 0.77, 1.55, 2.77, 6.09, 13.3mg/l　　　

1 日本環境省　生態リスク初期評価

2020/01/08

藻類

Pseudokirchneriella subcapitata

成長速度

NOErC

hours

0.497

mg/L

○

対照区,　助剤対照区,　0.570, 1.00, 1.80, 3.20, 5.70mg/l

0.153, 0.268, 0.497, 0.919, 1.88mg/l

1 日本環境省　生態リスク初期評価

2020/01/10

藻類

Pseudokirchneriella subcapitata

収量

NOEyC

hours

0.268

mg/L

○

対照区,　助剤対照区,　0.570, 1.00, 1.80, 3.20, 5.70mg/l

0.153, 0.268, 0.497, 0.919, 1.88mg/l

1 日本環境省　生態リスク初期評価

2020/01/10

藻類

Pseudokirchneriella subcapitata

NOEC

hours

>=5.6

mg/L

4 OECD SIDS (HPVC)

2020/01/17

藻類

Selenastrum capricornutum

Biomass

NOEC

days

4600

μg/L

6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）

環境庁

平成11年度　生態影響試験実施事業報告

2000

2020/02/14

藻類

Pseudokirchneriella subcapitata

Cell density (biomass)

NOEC

hours

>=5.6

mg/L

0.34, 0.76, 1.5, 3.0, 5.6mg/l, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Life Sciences

Toxicity of tetrabromobisphenol A to the freshwater green alga Selenastrum capricornutum.

Report No 88-10-2828. Springborn Life Sciences, Inc., Wareham, Massachusetts

1988

2019/12/27

藻類

Pseudokirchneriella subcapitata

Cell density (biomass)

NOEC

hours

>=5.6

mg/L

0.34, 0.76, 1.5, 3.0, 5.6mg/l, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Life Sciences

Toxicity of tetrabromobisphenol A to the freshwater green alga Selenastrum capricornutum.

Report No 88-10-2828. Springborn Life Sciences, Inc., Wareham, Massachusetts

1988

2019/12/27

藻類

Pseudokirchneriella subcapitata

PopulationAbundance

NOEC NOEC

hours

4.8

μM [Active ingredient]

0 uM / 1.8 uM / 4.8 uM / 9.2 uM / 12.9 uM / 16.5 uM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise

Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays

Chemosphere85(1)

2011

藻類

Pseudokirchneriella subcapitata

PopulationAbundance

LOEC LOEC

hours

9.2

μM [Active ingredient]

0 uM / 1.8 uM / 4.8 uM / 9.2 uM / 12.9 uM / 16.5 uM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise

Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays

Chemosphere85(1)

2011

藻類

Pseudokirchneriella subcapitata

PopulationPopulation growth rate

LOEC LOEC

hours

9.2

μM [Active ingredient]

0 uM / 1.8 uM / 4.8 uM / 9.2 uM / 12.9 uM / 16.5 uM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise

Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays

Chemosphere85(1)

2011

藻類

Pseudokirchneriella subcapitata

PopulationAbundance

LOEC LOEC

hours

9.2

μM [Active ingredient]

0 uM / 1.8 uM / 4.8 uM / 9.2 uM / 12.9 uM / 16.5 uM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise

Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays

Chemosphere85(1)

2011

藻類

Pseudokirchneriella subcapitata

PopulationPopulation growth rate

LOEC LOEC

hours

9.2

μM [Active ingredient]

0 uM / 1.8 uM / 4.8 uM / 9.2 uM / 12.9 uM / 16.5 uM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise

Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays

Chemosphere85(1)

2011

藻類

Pseudokirchneriella subcapitata

PopulationPopulation growth rate

NOEC NOEC

hours

4.8

μM [Active ingredient]

0 uM / 1.8 uM / 4.8 uM / 9.2 uM / 12.9 uM / 16.5 uM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise

Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays

Chemosphere85(1)

2011

藻類

Pseudokirchneriella subcapitata

PopulationPopulation growth rate

NOEC NOEC

hours

4.8

μM [Active ingredient]

0 uM / 1.8 uM / 4.8 uM / 9.2 uM / 12.9 uM / 16.5 uM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise

Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays

Chemosphere85(1)

2011

藻類

Pseudokirchneriella subcapitata

PopulationAbundance

NOEC NOEC

hours

4.8

μM [Active ingredient]

0 uM / 1.8 uM / 4.8 uM / 9.2 uM / 12.9 uM / 16.5 uM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Debenest,T., A.N. Petit, F. Gagne, M. Kohli, N. Nguyen, and C. Blaise

Comparative Toxicity of a Brominated Flame Retardant (Tetrabromobisphenol A) on Microalgae with Single and Multi-Species Bioassays

Chemosphere85(1)

2011

藻類

Pseudokirchneriella subcapitata

cell number

NOEC

hours

5.6

mg/L

○

0.60, 1.2, 2.4, 4.8, 9.6 mg/L TBBPA

0.34, 0.76, 1.5, 3.0, 5.6 mg/L TBBPA

12 ECHA Information on Registered Substances

study report

1988

藻類

Pseudokirchneriella subcapitata

NOEC

hours

0.5

mg/L

1 日本環境省　生態リスク初期評価

環境省

（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）

2016/11/09

藻類

Pseudokirchneriella subcapitata

NOEC

hours

4.6

mg/L

1 日本環境省　生態リスク初期評価

環境省

（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）

2016/11/09

藻類

Pseudokirchneriella subcapitata

NOEC

hours

0.27

mg/L

1 日本環境省　生態リスク初期評価

環境省

（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）

2016/11/09

藻類

Pseudokirchneriella subcapitata

NOEC

hours

mg/L

1 日本環境省　生態リスク初期評価

環境省

（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）

2016/11/09

藻類

Selenastrum capricornutum

生長阻害　24-72h

NOErC

hours

1.8

mg/L

11 Japan チャレンジプログラム

2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験

EAI95005

2016/03/08

藻類

Pseudokirchneriella subcapitata

biomass

NOEC

hours

>=5.6

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Life Sciences

Toxicity of tetrabromobisphenol A to the freshwater green alga Selenastrum capricornutum.

Report No 88-10-2828. Springborn Life Sciences, Inc., Wareham, Massachusetts.

1988

2016/03/04

藻類

Pseudokirchneriella subcapitata

biomass

NOEC

hours

>=5.6

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Life Sciences

Toxicity of tetrabromobisphenol A to the freshwater green alga Selenastrum capricornutum.

Report No 88-10-2828. Springborn Life Sciences, Inc., Wareham, Massachusetts.

1988

2016/03/04

藻類

Selenastrum capricornutum

生長阻害　24-72h

NOErC

hours

4.6

mg/L

11 Japan チャレンジプログラム

4，4’一イソプロピリデンビス（2，6一ジブロモフェノール）の藻類（Selenastrum capricornutum)に対する生長阻害試験

9B434G

2016/03/08

藻類

Pseudokirchneriella subcapitata

生長阻害

NOErC

hours

0.497

mg/L

11 Japan チャレンジプログラム

2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験

A050386

2016/03/08

藻類

Selenastrum capricornutum

cell density

NOEC

hours

0.35

mg/L

10 EHC (Environmental Health Criteria)

Giddings JM

Toxicity of tetrabromobisphenol A to the freshwater green alga Selenastrum capricornutum.

Wareham, Massachusetts, Springborn Life Sciences, Inc. (Report No. 88-10-2828 submitted to WHO by the Brominated Flame Retardant Industry Panel).

1988

2016/03/04

藻類

Pseudokirchneriella subcapitata

生長阻害

NOEbC

hours

0.268

mg/L

11 Japan チャレンジプログラム

2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験

A050386

2016/03/08

藻類

Selenastrum capricornutum

Biomass

NOEC

days

4600

μg/L

6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）

環境庁

平成 11 年度　生態影響試験実施事業報告

2000

2016/03/04

藻類

Pseudokirchneriella subcapitata

生長阻害

NOEyC

hours

0.268

mg/L

11 Japan チャレンジプログラム

2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験

A050386

2016/03/08

藻類

Selenastrum capricornutum

生長阻害

NOEbC

hours

4.6

mg/L

11 Japan チャレンジプログラム

4，4’一イソプロピリデンビス（2，6一ジブロモフェノール）の藻類（Selenastrum capricornutum)に対する生長阻害試験

9B434G

2016/03/08

藻類

Selenastrum capricornutum

生長阻害　24-48h

NOErC

hours

3.2

mg/L

11 Japan チャレンジプログラム

2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験

EAI95005

2016/03/08

藻類

Selenastrum capricornutum

生長阻害　24-48h

NOErC

hours

9.55

mg/L

11 Japan チャレンジプログラム

4，4’一イソプロピリデンビス（2，6一ジブロモフェノール）の藻類（Selenastrum capricornutum)に対する生長阻害試験

9B434G

2016/03/08

藻類

Selenastrum capricornutum

生長阻害

NOEbC

hours

mg/L

11 Japan チャレンジプログラム

2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンの藻類（Selenastrum capricornutum)に対する生長阻害試験

EAI95005

2016/03/08

藻類

Chlorella pyrenoidosa

cell number

NOEC

hours

3.7

μM

0 uM / 0.3 uM / 0.9 uM / 1.8 uM / 3.7 uM / 9.2 uM

16 ECOTOX

Peng,F.Q., G.G. Ying, B. Yang, Y.S. Liu, H.J. Lai, G.J. Zhou, J. Chen, and J.L. Zhao

Biotransformation of the Flame Retardant Tetrabromobisphenol-A (TBBPA) by Freshwater Microalgae

Environ. Toxicol. Chem.33(8)

2020/11/12

藻類

Scenedesmus acutus var. acutus

cell number

LOEC

hours

9.2

μM

0 uM / 0.3 uM / 0.9 uM / 1.8 uM / 3.7 uM / 9.2 uM

16 ECOTOX

Peng,F.Q., G.G. Ying, B. Yang, Y.S. Liu, H.J. Lai, G.J. Zhou, J. Chen, and J.L. Zhao

Biotransformation of the Flame Retardant Tetrabromobisphenol-A (TBBPA) by Freshwater Microalgae

Environ. Toxicol. Chem.33(8)

2020/11/12

藻類

Selenastrum capricornutum

Growth

NOEC

hours

>=5.6

mg/L

0.34-5.6 mg/L

19 その他

IPCS

Environmental health criteria 172, Tetrabromobisphenol A and derivatives

Geneva, World Health Organization

2021/04/13

藻類

Scenedesmus acutus var. acutus

cell number

NOEC

hours

3.7

μM

0 uM / 0.3 uM / 0.9 uM / 1.8 uM / 3.7 uM / 9.2 uM

16 ECOTOX

Peng,F.Q., G.G. Ying, B. Yang, Y.S. Liu, H.J. Lai, G.J. Zhou, J. Chen, and J.L. Zhao

Biotransformation of the Flame Retardant Tetrabromobisphenol-A (TBBPA) by Freshwater Microalgae

Environ. Toxicol. Chem.33(8)

2020/11/12

藻類

Chlorella pyrenoidosa

cell number

NOEC

hours

3.7

μM

0 uM / 0.3 uM / 0.9 uM / 1.8 uM / 3.7 uM / 9.2 uM

16 ECOTOX

Peng,F.Q., G.G. Ying, B. Yang, Y.S. Liu, H.J. Lai, G.J. Zhou, J. Chen, and J.L. Zhao

Biotransformation of the Flame Retardant Tetrabromobisphenol-A (TBBPA) by Freshwater Microalgae

Environ. Toxicol. Chem.33(8)

2020/11/12

藻類

Chlorella pyrenoidosa

cell number

LOEC

hours

9.2

μM

0 uM / 0.3 uM / 0.9 uM / 1.8 uM / 3.7 uM / 9.2 uM

16 ECOTOX

Peng,F.Q., G.G. Ying, B. Yang, Y.S. Liu, H.J. Lai, G.J. Zhou, J. Chen, and J.L. Zhao

Biotransformation of the Flame Retardant Tetrabromobisphenol-A (TBBPA) by Freshwater Microalgae

Environ. Toxicol. Chem.33(8)

2020/11/12

藻類

Chlorella pyrenoidosa

cell number

LOEC

hours

9.2

μM

0 uM / 0.3 uM / 0.9 uM / 1.8 uM / 3.7 uM / 9.2 uM

16 ECOTOX

Peng,F.Q., G.G. Ying, B. Yang, Y.S. Liu, H.J. Lai, G.J. Zhou, J. Chen, and J.L. Zhao

Biotransformation of the Flame Retardant Tetrabromobisphenol-A (TBBPA) by Freshwater Microalgae

Environ. Toxicol. Chem.33(8)

2020/11/12

藻類

Scenedesmus acutus var. acutus

cell number

LOEC

hours

9.2

μM

0 uM / 0.3 uM / 0.9 uM / 1.8 uM / 3.7 uM / 9.2 uM

16 ECOTOX

Peng,F.Q., G.G. Ying, B. Yang, Y.S. Liu, H.J. Lai, G.J. Zhou, J. Chen, and J.L. Zhao

Biotransformation of the Flame Retardant Tetrabromobisphenol-A (TBBPA) by Freshwater Microalgae

Environ. Toxicol. Chem.33(8)

2020/11/12

藻類

Scenedesmus acutus var. acutus

cell number

NOEC

hours

3.7

μM

0 uM / 0.3 uM / 0.9 uM / 1.8 uM / 3.7 uM / 9.2 uM

16 ECOTOX

Peng,F.Q., G.G. Ying, B. Yang, Y.S. Liu, H.J. Lai, G.J. Zhou, J. Chen, and J.L. Zhao

Biotransformation of the Flame Retardant Tetrabromobisphenol-A (TBBPA) by Freshwater Microalgae

Environ. Toxicol. Chem.33(8)

2020/11/12

甲殻類

Acartia tonsa

Population//Sex ratio

LOEC

days

200

μg/L

0 ug/L / 0 ug/L / 1.3 ug/L / 25 ug/L / 50 ug/L / 1

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Acartia tonsa

Population//Sex ratio

EC50

days

158

μg/L

0 ug/L / 0 ug/L / 1.3 ug/L / 25 ug/L / 50 ug/L / 1

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Acartia tonsa

Development//Developmental changes, general

EC20

hours

3.3

μg/L

0 ug/L / 0 ug/L / 11.5 ug/L / 23 ug/L / 47 ug/L /

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Acartia tonsa

Development//Developmental changes, general

EC10

hours

1.4

μg/L

0 ug/L / 0 ug/L / 11.5 ug/L / 23 ug/L / 47 ug/L /

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Acartia tonsa

Growth(Length)

EC10

days

180

μg/L

0 ug/L / 0 ug/L / 1.3 ug/L / 25 ug/L / 50 ug/L / 1

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Acartia tonsa

Development//Developmental changes, general

EC50

hours

μg/L

0 ug/L / 0 ug/L / 11.5 ug/L / 23 ug/L / 47 ug/L /

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Acartia tonsa

Population//Sex ratio

EC20

days

113

μg/L

0 ug/L / 0 ug/L / 1.3 ug/L / 25 ug/L / 50 ug/L / 1

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Acartia tonsa

Population//Sex ratio

EC10

days

μg/L

0 ug/L / 0 ug/L / 1.3 ug/L / 25 ug/L / 50 ug/L / 1

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Daphnia magna

Reproduction

NOEC

days

1.3

mg/L

0 mg/L / 0.31 mg/L / 0.63 mg/L / 1.3 mg/L / 2.5 mg

16 ECOTOX

Great Lakes Chemical Corp.

The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989

EPA/OTS 40-8998117

2020/11/12

甲殻類

Acartia tonsa

Population//Sex ratio

NOEC

days

100

μg/L

0 ug/L / 0 ug/L / 1.3 ug/L / 25 ug/L / 50 ug/L / 1

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Daphnia magna

Reproduction

LOEC

days

2.5

mg/L

0 mg/L / 0.31 mg/L / 0.63 mg/L / 1.3 mg/L / 2.5 mg

16 ECOTOX

Great Lakes Chemical Corp.

The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989

EPA/OTS 40-8998117

2020/11/12

甲殻類

Mytilus edulis

growth

LOEC

days

μg/L

○

19, 38, 75, 150, 300 µg/L

17, 32, 62, 126, 226 µg/L

12 ECHA Information on Registered Substances

study report

2005

甲殻類

Crassostrea virginica

other: shell deposition

EC50

hours

μg/L

○

19, 32, 54, 90, 150 µg a.i./L

Measured (mean): 18 (3.9), 32 (5.4), 51 (11), 87 (18), 150 (22) µg a.i./L

12 ECHA Information on Registered Substances

study report

1989

甲殻類

Mytilus edulis

growth

LOEC

days

126

μg/L

○

19, 38, 75, 150, 300 µg/L

17, 32, 62, 126, 226 µg/L

12 ECHA Information on Registered Substances

study report

2005

甲殻類

Mytilus edulis

growth

LOEC

days

μg/L

○

19, 38, 75, 150, 300 µg/L

17, 32, 62, 126, 226 µg/L

12 ECHA Information on Registered Substances

study report

2005

甲殻類

Mytilus edulis

growth

NOEC

days

μg/L

○

19, 38, 75, 150, 300 µg/L

17, 32, 62, 126, 226 µg/L

12 ECHA Information on Registered Substances

study report

2005

甲殻類

Crassostrea virginica

other: shell deposition

NOEC

hours

<18

μg/L

○

19, 32, 54, 90, 150 µg a.i./L

Measured (mean): 18 (3.9), 32 (5.4), 51 (11), 87 (18), 150 (22) µg a.i./L

12 ECHA Information on Registered Substances

study report

1989

甲殻類

Mytilus edulis

growth

NOEC

days

μg/L

○

19, 38, 75, 150, 300 µg/L

17, 32, 62, 126, 226 µg/L

12 ECHA Information on Registered Substances

study report

2005

甲殻類

Daphnia magna

No Group Code

EC50

days

>0.9～<1.2

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2): 199-204

1993

2016/03/25

甲殻類

Daphnia magna

No Group Code

EC50

days

>0.9～<1.2

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2): 199-204

1993

2016/03/25

甲殻類

Daphnia magna

No Group Code

EC50

days

>0.9～<1.2

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2): 199-204

1993

2016/03/25

甲殻類

Daphnia magna

No Group Code

EC50

days

>0.9～<1.2

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2): 199-204

1993

2016/03/25

甲殻類

Daphnia magna

Mortality

EC50

days

7900

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Brooke,L.T.

Results of Freshwater Exposures with the Chemicals Atrazine, Biphenyl, Butachlor, Carbaryl, Carbazole, Dibenzofuran, 3,3'-Dichlorobenzidine, Dichlorvos, 1,2-Epoxyethylbenzene (Styrene Oxide), Isophorone, Isopropalin, Oxy

Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI:110 p.

1991

2016/03/25

甲殻類

Chironomus tentans

Survival

LOEC

days

0.2

mg/L

19 その他

Brominated Flame Retardants Industry Panel

The subchronic toxicity of sediment-sorbed tetrabromobisphenol A to Chironomus tentans under flow-through conditions.

Amended Final Report. Springborn Laboratories, Inc. Report #89-08-3067, Study #1199-1287-6107-128. October 6, 1989.

2021/04/14

甲殻類

Chironomus tentans

LC50

days

0.13

mg/L

19 その他

Brominated Flame Retardants Industry Panel

The subchronic toxicity of sediment-sorbed tetrabromobisphenol A to Chironomus tentans under flow-through conditions.

Amended Final Report. Springborn Laboratories, Inc. Report #89-08-3067, Study #1199-1287-6107-128. October 6, 1989.

2021/04/14

甲殻類

Chironomus tentans

Growth(Weight)

NOEC

days

0.045

AI mg/L

<0.0075-<0.0077 AI mg/L / <0.0074-<0.0075 AI mg/L

16 ECOTOX

Springborn Laboratories Inc.

The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689

EPA/OTS Doc.#40-8998109

2020/11/12

甲殻類

Chironomus tentans

Survival

NOEC

days

0.045

AI mg/L

<0.0075-<0.0077 AI mg/L / <0.0074-<0.0075 AI mg/L

16 ECOTOX

Springborn Laboratories Inc.

The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689

EPA/OTS Doc.#40-8998109

2020/11/12

甲殻類

Chironomus tentans

Growth(Weight)

NOEC

days

0.045

AI mg/L

<0.0075-<0.0077 AI mg/L / <0.0074-<0.0075 AI mg/L

16 ECOTOX

Springborn Laboratories Inc.

The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689

EPA/OTS Doc.#40-8998109

2020/11/12

甲殻類

Chironomus tentans

NOEL

days

0.045

mg/L

0.0075-0.045 mg/L

19 その他

IPCS

Environmental health criteria 172, Tetrabromobisphenol A and derivatives

Geneva, World Health Organization

2021/04/13

甲殻類

Chironomus tentans

Growth(Weight)

NOEC

days

0.046

AI mg/L

<0.00042-<0.0011 AI mg/L / <0.00041-<0.00048 AI mg

16 ECOTOX

Springborn Laboratories Inc.

The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689

EPA/OTS Doc.#40-8998109

2020/11/12

甲殻類

Chironomus tentans

Growth(Weight)

NOEC

days

0.046

AI mg/L

<0.00042-<0.0011 AI mg/L / <0.00041-<0.00048 AI mg

16 ECOTOX

Springborn Laboratories Inc.

The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689

EPA/OTS Doc.#40-8998109

2020/11/12

甲殻類

Chironomus tentans

Mortality

LC50

days

0.13

AI mg/L

<0.023-<0.024 AI mg/L / <0.022-<0.024 AI mg/L / 0.

16 ECOTOX

Springborn Laboratories Inc.

The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689

EPA/OTS Doc.#40-8998109

2020/11/12

甲殻類

Chironomus tentans

Growth(Weight)

LOEC

days

0.066

AI mg/L

<0.023-<0.024 AI mg/L / <0.022-<0.024 AI mg/L / 0.

16 ECOTOX

Springborn Laboratories Inc.

The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689

EPA/OTS Doc.#40-8998109

2020/11/12

甲殻類

Chironomus tentans

Survival

NOEC

days

0.12

AI mg/L

<0.023-<0.024 AI mg/L / <0.022-<0.024 AI mg/L / 0.

16 ECOTOX

Springborn Laboratories Inc.

The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689

EPA/OTS Doc.#40-8998109

2020/11/12

甲殻類

Chironomus tentans

Survival

NOEC

days

0.046

AI mg/L

<0.0074-<0.0079 AI mg/L / <0.0074-<0.0075 AI mg/L

16 ECOTOX

Springborn Laboratories Inc.

The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689

EPA/OTS Doc.#40-8998109

2020/11/12

甲殻類

Chironomus tentans

Growth(Weight)

NOEC

days

0.046

AI mg/L

<0.0074-<0.0079 AI mg/L / <0.0074-<0.0075 AI mg/L

16 ECOTOX

Springborn Laboratories Inc.

The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689

EPA/OTS Doc.#40-8998109

2020/11/12

甲殻類

Chironomus tentans

Growth(Weight)

NOEC

days

0.046

AI mg/L

<0.0074-<0.0079 AI mg/L / <0.0074-<0.0075 AI mg/L

16 ECOTOX

Springborn Laboratories Inc.

The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689

EPA/OTS Doc.#40-8998109

2020/11/12

甲殻類

Chironomus tentans

Growth(Weight)

MATC

days

0.07

AI mg/L

<0.023-<0.024 AI mg/L / <0.022-<0.024 AI mg/L / 0.

16 ECOTOX

Springborn Laboratories Inc.

The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689

EPA/OTS Doc.#40-8998109

2020/11/12

甲殻類

Chironomus tentans

Survival

LOEC

days

0.2

AI mg/L

<0.023-<0.024 AI mg/L / <0.022-<0.024 AI mg/L / 0.

16 ECOTOX

Springborn Laboratories Inc.

The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689

EPA/OTS Doc.#40-8998109

2020/11/12

甲殻類

Chironomus tentans

Survival

NOEC

days

0.046

AI mg/L

<0.00042-<0.0011 AI mg/L / <0.00041-<0.00048 AI mg

16 ECOTOX

Springborn Laboratories Inc.

The Subchronic Toxicity of Sediment-Sorbed Tetrabromobisphenol A to Chironomus tentans Under Flow-Through Conditions (Final Report) with Cover Sheet and Letter Dated 101689

EPA/OTS Doc.#40-8998109

2020/11/12

甲殻類

Chironomus tentans

NOEL

days

0.046

mg/L

0.0078-0.046 mg/L

19 その他

IPCS

Environmental health criteria 172, Tetrabromobisphenol A and derivatives

Geneva, World Health Organization

2021/04/13

甲殻類

Chironomus tentans

NOEL

days

0.046

mg/L

0.0044-0.046 mg/L

19 その他

IPCS

Environmental health criteria 172, Tetrabromobisphenol A and derivatives

Geneva, World Health Organization

2021/04/13

甲殻類

Daphnia magna

EC50

hours

1000

μg/L

14 BUA Report

Lee SK, Freitag, D, Steinberg C, Kettrup A, Kim YH

Effects of dissolved humic material on acute toxicity of some organic chemicals to aquatic organisms.

Wat Res 27(2)

1993

2020/01/21

甲殻類

Daphnia magna

Immobilization

EC0

hours

3.6

mg/L

0, 2.00, 3.60, 6.30, 11.0, 20.0mg/l

設定値の96～98％（0h)、97～99％（48h)

18 既存化学物質安全性(ハザード)評価シート

環境省

既存化学物質審査シート（三監No.10）

2020/01/08

甲殻類

Daphnia magna

Immobilization

EC50

hours

7.87

mg/L

0, 2.00, 3.60, 6.30, 11.0, 20.0mg/l

設定値の96～98％（0h)、97～99％（48h)

18 既存化学物質安全性(ハザード)評価シート

環境省

既存化学物質審査シート（三監No.10）

2020/01/08

甲殻類

Daphnia magna

EC50

hours

960

μg/L

14 BUA Report

Velsicol Chemical Corporation

The acute toxicity of tetrabromobisphenol A to the water flea, Daphnia magna Straus. UCES Project: 11506-03-52

1978

2020/01/22

甲殻類

Daphnia magna

Immob.

EC50

hours

μg/L

7 EU Risk Assessment Report (EUリスク評価書）

Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.

Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.

Water Research, 27

1993

2019/12/27

甲殻類

Daphnia magna

EC50

hours

0.96

mg/L

4 OECD SIDS (HPVC)

2020/01/17

甲殻類

Daphnia magna

Immob.

EC50

hours

0.94

μg/L

7 EU Risk Assessment Report (EUリスク評価書）

Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.

Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.

Water Research, 27

1993

2019/12/27

甲殻類

Daphnia magna

Immobilisation

EC50

days

1000～2000

μg/L

310, 630, 1300, 2500, 5000µg/l

14 BUA Report

Great Lakes Chemical Corporation

The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions. Springborn Laboratories, SLS Report: 89-1-2925

1989

2020/01/22

甲殻類

Nitocra spinipes

Larval development

EC0

hours

>=35

μg/L

14 BUA Report

Breitholtz M, Wollenberger L, Bengtsson BE, Kusk OK

Impacts of brominated flame retardants on development and reproduction of two copepod species, Nitocra spinipes and Acartia tonsa.

The Second International Workshop on Brominated Flame Retardants, May 14-16, 2001, Stockholm, Sweden, abstract volume

2001

2020/01/22

甲殻類

Daphnia magna

Mortality

LC50

hours

0.96

mg/L

0.32, 0.56, 1.00, 1.80 and 3.20mg/l plus control and solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Union Carbide Corporation

The acute toxicity of FMBP 4A (tetrabromobisphenol A) to the water flea Daphnia magna Straus.

UCES Project Number 11506-03-52. Union Carbide Environmental Services, New York.

1978

2019/12/24

甲殻類

Daphnia magna

NOEC

hours

<0.32

mg/L

14 BUA Report

Velsicol Chemical Corporation

The acute toxicity of tetrabromobisphenol A to the water flea, Daphnia magna Straus. UCES Project: 11506-03-52

1978

2020/01/21

甲殻類

Crassostrea virginica

Shell deposition

EC50

hours

0.12

mg/L

0.075, 0.100, 0.160, 0.260,0.310mg/l, control, acetone control

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Life Sciences

Acute toxicity of tetrabromobisphenol A to eastern oysters (Crassostrea virginica) under flow-through conditions.

Report No 89-1-2898. Springborn Life Sciences, Inc., Wareham, Massachusetts

1989

2019/12/27

甲殻類

Daphnia magna

Immobilization

EC100

hours

mg/L

○

対照区，助剤対照区，2.00, 3.60, 6.30, 11.0, 20.0mg/l

1.96, 3.47, 6.12, 10.6, 19.6mg/l

1 日本環境省　生態リスク初期評価

2020/01/08

甲殻類

Daphnia magna

Immobilization

NOEC

hours

3.6

mg/L

○

対照区，助剤対照区，2.00, 3.60, 6.30, 11.0, 20.0mg/l

1.96, 3.47, 6.12, 10.6, 19.6mg/l

1 日本環境省　生態リスク初期評価

2020/01/10

甲殻類

Daphnia magna

Immobilization

EC50

hours

7.87

mg/L

○

対照区，助剤対照区，2.00, 3.60, 6.30, 11.0, 20.0mg/l

1.96, 3.47, 6.12, 10.6, 19.6mg/l

1 日本環境省　生態リスク初期評価

2020/01/08

甲殻類

Daphnia magna

Immobilization

EC100

hours

mg/L

○

対照区，助剤対照区，2.00, 3.60, 6.30, 11.0, 20.0mg/l

1.96, 3.47, 6.12, 10.6, 19.6mg/l

1 日本環境省　生態リスク初期評価

2020/01/08

甲殻類

Daphnia magna

Immobilization

NOEC

hours

6.3

mg/L

○

対照区，助剤対照区，2.00, 3.60, 6.30, 11.0, 20.0mg/l

1.96, 3.47, 6.12, 10.6, 19.6mg/l

1 日本環境省　生態リスク初期評価

2020/01/10

甲殻類

Daphnia magna

Immob.

EC50

hours

7.9

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Brooke L. T.

Results of freshwater exposures with the chemicals atrazine, biphenyl, butachlor, carbaryl, carbazole, dibenzofuran, 3,3-dichlorobenzidine, dichlorvos….

Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

1991

2019/12/25

甲殻類

Daphnia magna

Immob.

NOEC

hours

>=1.8

mg/L

1.2, 1.8mg/l, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Wildlife International

Tetrabromobisphenol A: A 48-hour flow-through acute toxicity test with the cladoceran (Daphnia magna).

Wildlife International Ltd., Project Number 439A-124

2003

2019/12/27

甲殻類

Acartia tonsa

Mortality

LC50

hours

0.4

mg/L

Six concentrations between 0.1 and 0.5mg/l,control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Wollenberger L., Dinan L. and Breitholtz M.

Effects of brominated flame retardants on two marine copepod species, Acartia tonsa and Nitocra spinipes, and on the Ecdysterodresponsive Drosophila malanogaster BII-cell-line.

Organohalogen Compounds, 57

2002

2019/12/27

甲殻類

Acartia tonsa

Mortality

LC10

hours

0.3

mg/L

Six concentrations between 0.1 and 0.5mg/l, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Wollenberger L., Dinan L. and Breitholtz M.

Effects of brominated flame retardants on two marine copepod species, Acartia tonsa and Nitocra spinipes, and on the Ecdysterodresponsive Drosophila malanogaster BII-cell-line.

Organohalogen Compounds, 57

2002

2019/12/27

甲殻類

Daphnia magna

Immobilization

EC50

hours

9.25

mg/L

○

対照区，助剤対照区，2.00, 3.60, 6.30, 11.0, 20.0mg/l

1.96, 3.47, 6.12, 10.6, 19.6mg/l

1 日本環境省　生態リスク初期評価

2020/01/08

甲殻類

Daphnia magna

Immob.

EC50

hours

0.95

μg/L

7 EU Risk Assessment Report (EUリスク評価書）

Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.

Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.

Water Research, 27

1993

2019/12/27

甲殻類

Crassostrea virginica

Shell deposition

EC50

hours

0.098

mg/L

0.018, 0.032, 0.051, 0.087, 0.15mg/l, control, acetone control

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Life Sciences

Acute toxicity of tetrabromobisphenol A to eastern oysters (Crassostrea virginica) under flow-through conditions.

Report No 89-1-2898. Springborn Life Sciences, Inc., Wareham, Massachusetts

1989

2019/12/27

甲殻類

Daphnia magna

Immob.

EC50

hours

0.94

μg/L

7 EU Risk Assessment Report (EUリスク評価書）

Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.

Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.

Water Research, 27

1993

2019/12/27

甲殻類

Mysidopsis bahia

Mortality

LC50

hours

1.1

mg/L

GC method

7 EU Risk Assessment Report (EUリスク評価書）

Goodman L. R., Cripe G. M., Moody P. H. and Halsell D. G.

Acute toxicity of malathion, tetrabromobisphenol-A, and tributyltin chloride to mysids (Mysidopsis bahia) of three ages.

Bull. Environ. Contam. Toxicol., 41

1988

2019/12/27

甲殻類

Acartia tonsa

LC50

hours

400

μg/L

14 BUA Report

Breitholtz M, Wollenberger L, Bengtsson BE, Kusk OK

Impacts of brominated flame retardants on development and reproduction of two copepod species, Nitocra spinipes and Acartia tonsa.

The Second International Workshop on Brominated Flame Retardants, May 14-16, 2001, Stockholm, Sweden, abstract volume

2001

2020/01/21

甲殻類

Nitocra spinipes

Larval development

LC50

hours

350

μg/L

14 BUA Report

Breitholtz M, Wollenberger L, Bengtsson BE, Kusk OK

Impacts of brominated flame retardants on development and reproduction of two copepod species, Nitocra spinipes and Acartia tonsa.

The Second International Workshop on Brominated Flame Retardants, May 14-16, 2001, Stockholm, Sweden, abstract volume

2001

2020/01/21

甲殻類

Crassostrea virginica

Growth

NOEC

hours

6.2

μg/L

○

18, 32, 51, 87, 150µg/l

14 BUA Report

Great Lakes Chemical Corporation

Acute toxicity of tetrabromobisphenol A to eastern oysters (Crassostrea virginica) under flow-through conditions. Springborn Laboratories, SLS Report: 89-1-2898

1989

2020/01/21

甲殻類

Crassostrea virginica

Growth

EC10

hours

6.2

μg/L

○

18, 32, 51, 87, 150µg/l

14 BUA Report

Great Lakes Chemical Corporation

Acute toxicity of tetrabromobisphenol A to eastern oysters (Crassostrea virginica) under flow-through conditions. Springborn Laboratories, SLS Report: 89-1-2898

1989

2020/01/21

甲殻類

Mysidopsis bahia

LC50

hours

860

μg/L

14 BUA Report

Goodman L, Cripe G, Moody P, Halsell D

Acute toxicity of malathione, tetrabromobisphenol A and tributyltin chloride to Mysids (Mysidopsis bahia) of three ages.

Bull Environ Contam Toxicol 41

1988

2020/01/21

甲殻類

Crassostrea virginica

Shell deposition

EC10

hours

0.0026～0.0062

mg/L

0.018, 0.032, 0.051, 0.087, 0.15mg/l, control, acetone control

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Life Sciences

Acute toxicity of tetrabromobisphenol A to eastern oysters (Crassostrea virginica) under flow-through conditions.

Report No 89-1-2898. Springborn Life Sciences, Inc., Wareham, Massachusetts

1989

2019/12/27

甲殻類

Crassostrea virginica

Growth

EC50

hours

μg/L

○

18, 32, 51, 87, 150µg/l

14 BUA Report

Great Lakes Chemical Corporation

Acute toxicity of tetrabromobisphenol A to eastern oysters (Crassostrea virginica) under flow-through conditions. Springborn Laboratories, SLS Report: 89-1-2898

1989

2020/01/21

甲殻類

Mysidopsis bahia

Mortality

LC50

hours

0.86

mg/L

GC method

7 EU Risk Assessment Report (EUリスク評価書）

Goodman L. R., Cripe G. M., Moody P. H. and Halsell D. G.

Acute toxicity of malathion, tetrabromobisphenol-A, and tributyltin chloride to mysids (Mysidopsis bahia) of three ages.

Bull. Environ. Contam. Toxicol., 41

1988

2019/12/27

甲殻類

Mysidopsis bahia

LC50

hours

1200

μg/L

14 BUA Report

Goodman L, Cripe G, Moody P, Halsell D

Acute toxicity of malathione, tetrabromobisphenol A and tributyltin chloride to Mysids (Mysidopsis bahia) of three ages.

Bull Environ Contam Toxicol 41

1988

2020/01/21

甲殻類

Mysidopsis bahia

LC50

hours

1100

μg/L

14 BUA Report

Goodman L, Cripe G, Moody P, Halsell D

Acute toxicity of malathione, tetrabromobisphenol A and tributyltin chloride to Mysids (Mysidopsis bahia) of three ages.

Bull Environ Contam Toxicol 41

1988

2020/01/21

甲殻類

Nitocra spinipes

Mortality

LC50

hours

0.35

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Breitholtz M., Wollenberger L., Bengtsson B-E. and Kusk K. O.

Impact of brominated flame retardants on development and reproduction of two copepod species, Nitocra spinipes and Acartia tonsa.

Second International Workshop on Brominated Flame Retardants, May 14-16, Stockholm University, Sweden

2001

2019/12/25

甲殻類

Mysidopsis bahia

Mortality

LC50

hours

1.2

mg/L

GC method

7 EU Risk Assessment Report (EUリスク評価書）

Goodman L. R., Cripe G. M., Moody P. H. and Halsell D. G.

Acute toxicity of malathion, tetrabromobisphenol-A, and tributyltin chloride to mysids (Mysidopsis bahia) of three ages.

Bull. Environ. Contam. Toxicol., 41

1988

2019/12/27

甲殻類

Mysidopsis bahia

Mortality

LC50

days

860

μg/L

6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）

Goodman,L.R., G.M.Cripe, P.H.Moody, and D.G.Halsell

Acute Toxicity of Malathion, Tetrabromobisphenol-A, and Tributyltin Chloride to Mysids (Mysidopsis bahia) of Three Ages.

Bull. Environ. Contam. Toxicol. 41(5)

1988

2020/02/14

甲殻類

Daphnia magna

Immobilization

EC50

days

7870

μg/L

6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）

環境庁

平成11年度　生態影響試験実施事業報告

2000

2020/02/14

甲殻類

Daphnia magna

IntoxicationImmobile

EC50 EC50

hours

>0.9～<1.2

μg/L [Active ingredient]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2)

1993

甲殻類

Americamysis bahia

MortalityMortality

LC50 LC50

hours

860

μg/L [Active ingredient]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Goodman,L.R., G.M. Cripe, P.H. Moody, and D.G. Halsell

Acute Toxicity of Malathion, Tetrabromobisphenol-A, and Tributyltin Chloride to Mysids (Mysidopsis bahia) of Three Ages

Bull. Environ. Contam. Toxicol.41(5)

1988

甲殻類

Daphnia magna

MortalityMortality

EC50 EC50

hours

7900

μg/L [Active ingredient]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Brooke,L.T.

Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI

1991

甲殻類

Americamysis bahia

MortalityMortality

LC50 LC50

hours

1200

μg/L [Active ingredient]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Goodman,L.R., G.M. Cripe, P.H. Moody, and D.G. Halsell

Acute Toxicity of Malathion, Tetrabromobisphenol-A, and Tributyltin Chloride to Mysids (Mysidopsis bahia) of Three Ages

Bull. Environ. Contam. Toxicol.41(5)

1988

甲殻類

Americamysis bahia

MortalityMortality

LC50 LC50

hours

1100

μg/L [Active ingredient]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Goodman,L.R., G.M. Cripe, P.H. Moody, and D.G. Halsell

Acute Toxicity of Malathion, Tetrabromobisphenol-A, and Tributyltin Chloride to Mysids (Mysidopsis bahia) of Three Ages

Bull. Environ. Contam. Toxicol.41(5)

1988

甲殻類

Daphnia magna

IntoxicationImmobile

EC50 EC50

hours

>0.9～<1.2

μg/L [Active ingredient]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2)

1993

甲殻類

Daphnia magna

IntoxicationImmobile

EC50 EC50

hours

>0.9～<1.2

μg/L [Active ingredient]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2)

1993

甲殻類

Daphnia magna

IntoxicationImmobile

EC50 EC50

hours

>1.8

mg/L [Active ingredient]

<0.250 AI mg/L / <0.250 AI mg/L / 1.2 (1.18-1.25) AI mg/L / 1.8 (1.71-1.85) AI mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Wildlife International Ltd.

Tetrabromobisphenol A: A 48-Hour Flow-Through Acute Toxicity Test with the Cladoceran (Daphnia magna)

Wildlife International, LTD. Project Number

2003

甲殻類

Daphnia magna

IntoxicationImmobile

EC50 EC50

hours

>1.8

mg/L [Active ingredient]

<0.250 AI mg/L / <0.250 AI mg/L / 1.2 (1.18-1.25) AI mg/L / 1.8 (1.71-1.85) AI mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Wildlife International Ltd.

Tetrabromobisphenol A: A 48-Hour Flow-Through Acute Toxicity Test with the Cladoceran (Daphnia magna)

Wildlife International, LTD. Project Number

2003

甲殻類

Daphnia magna

IntoxicationImmobile

EC50 EC50

hours

>0.9～<1.2

μg/L [Active ingredient]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2)

1993

甲殻類

Daphnia magna

IntoxicationImmobile

NOEC NOEC

hours

1.8

mg/L [Active ingredient]

<0.250 AI mg/L / <0.250 AI mg/L / 1.2 (1.18-1.25) AI mg/L / 1.8 (1.71-1.85) AI mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Wildlife International Ltd.

Tetrabromobisphenol A: A 48-Hour Flow-Through Acute Toxicity Test with the Cladoceran (Daphnia magna)

Wildlife International, LTD. Project Number

2003

甲殻類

Daphnia magna

mortality

NOEC

hours

<0.32

mg/L [nominal, test mat.]

control, solvent control, 0.32, 0.56, 1.00, 1.80, 3.20 mg/L

12 ECHA Information on Registered Substances

study report

1978

2020/03/18

甲殻類

Daphnia magna

mortality

LC50

hours

>1.8

mg/L

○

1.2, 1.8 mg a.i./L

12 ECHA Information on Registered Substances

study report

2003

甲殻類

Daphnia magna

mortality

NOEC

hours

1.8

mg/L

○

1.2, 1.8 mg a.i./L

12 ECHA Information on Registered Substances

study report

2003

甲殻類

Daphnia magna

mortality

LC50

hours

>1.8

mg/L

○

1.2, 1.8 mg a.i./L

12 ECHA Information on Registered Substances

study report

2003

甲殻類

Daphnia magna

mortality

LC50

hours

0.96

mg/L

control, solvent control, 0.32, 0.56, 1.00, 1.80, 3.20 mg/L

12 ECHA Information on Registered Substances

study report

1978

甲殻類

Daphnia magna

mortality

NOEC

hours

<0.32

mg/L

control, solvent control, 0.32, 0.56, 1.00, 1.80, 3.20 mg/L

12 ECHA Information on Registered Substances

study report

1978

甲殻類

Acartia tonsa

mortality

LC10

hours

300

μg/L

100 - 500 µg/L

12 ECHA Information on Registered Substances

Wollenberger L, Dinan L & Breitholtz M

BROMINATED FLAME RETARDANTS: ACTIVITIES IN A CRUSTACEAN DEVELOPMENT TEST AND IN AN ECDYSTEROID SCREENING ASSAY

Environ. Toxicol. Chem. 24

2005

甲殻類

Acartia tonsa

mortality

LC50

hours

400

μg/L

100 - 500 µg/L

12 ECHA Information on Registered Substances

Wollenberger L, Dinan L & Breitholtz M

BROMINATED FLAME RETARDANTS: ACTIVITIES IN A CRUSTACEAN DEVELOPMENT TEST AND IN AN ECDYSTEROID SCREENING ASSAY

Environ. Toxicol. Chem. 24

2005

甲殻類

Daphnia magna

mortality

LC50

hours

0.96

mg/L [nominal]

control, solvent control, 0.32, 0.56, 1.00, 1.80, 3.20 mg/L

12 ECHA Information on Registered Substances

study report

1978

2020/03/18

甲殻類

Daphnia magna

mortality

LC50

hours

>1.8

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

mortality

LC50

hours

>1.8

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

mortality

NOEC

hours

1.8

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

mortality

NOEC

hours

<0.32

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

mortality

LC50

hours

0.96

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

EC50

hours

7.9

mg/L

1 日本環境省　生態リスク初期評価

環境省

（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）

2016/11/09

甲殻類

Daphnia magna

immobility

EC50

hours

0.94

μg/L

7 EU Risk Assessment Report (EUリスク評価書）

Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.

Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.

Water Research, 27 Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

1993

2016/03/04

甲殻類

Daphnia magna

遊泳阻害

EiC50

hours

7.87

mg/L

11 Japan チャレンジプログラム

4，4'-イソプロピリデンビス（2，6一ジブロモフェノール）のオオミジンコ（Daphnia magna）に対する急性遊泳阻害試験

9B456G

2016/03/08

甲殻類

Daphnia magna

遊泳阻害

NOECi

hours

3.6

mg/L

11 Japan チャレンジプログラム

4，4'-イソプロピリデンビス（2，6一ジブロモフェノール）のオオミジンコ（Daphnia magna）に対する急性遊泳阻害試験

9B456G

2016/03/08

甲殻類

Daphnia magna

遊泳阻害

EiC100

hours

mg/L

11 Japan チャレンジプログラム

4，4'-イソプロピリデンビス（2，6一ジブロモフェノール）のオオミジンコ（Daphnia magna）に対する急性遊泳阻害試験

9B456G

2016/03/08

甲殻類

Daphnia magna

mortality

LC50

hours

0.96

mg/L

10 EHC (Environmental Health Criteria)

Morrissey AE

The acute toxicity of FMBP4A (tetrabromobisphenol A) to the water flea, Daphnia magna Straus.

Tarrytown, New York, Union Carbide Corporation, Environmental Services (Report to Velsicol Chemical Corporation, Chicago, submitted to WHO by the Brominated Flame Retardant Industry Panel)

1978

2016/03/04

甲殻類

Daphnia magna

Mortality

LC50

hours

0.96

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Union Carbide Corporation

The acute toxicity of FMBP 4A (tetrabromobisphenol A) to the water flea Daphnia magna Straus.

UCES Project Number 11506-03-52. Union Carbide Environmental Services, New York. Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

1978

2016/03/04

甲殻類

Daphnia magna

immobility

EC50

hours

μg/L

7 EU Risk Assessment Report (EUリスク評価書）

Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.

Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.

Water Research, 27 Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

1993

2016/03/04

甲殻類

Daphnia magna

immobility

EC50

hours

0.94

μg/L

7 EU Risk Assessment Report (EUリスク評価書）

Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.

Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.

Water Research, 27 Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

1993

2016/03/04

甲殻類

Daphnia magna

immobility

EC50

hours

7.9

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Brooke L. T.

Results of freshwater exposures with the chemicals atrazine, biphenyl, butachlor, carbaryl, carbazole, dibenzofuran, 3,3-dichlorobenzidine, dichlorvos….

Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database. Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

1991

2016/03/04

甲殻類

Daphnia magna

immobility

EC50

hours

0.95

μg/L

7 EU Risk Assessment Report (EUリスク評価書）

Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.

Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.

Water Research, 27 Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

1993

2016/03/04

甲殻類

Daphnia magna

Immobilization

EC50

days

7870

μg/L

6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）

環境庁

平成 11 年度　生態影響試験実施事業報告

2000

2016/03/05

甲殻類

Daphnia magna

遊泳阻害

EiC100

hours

mg/L

11 Japan チャレンジプログラム

2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンのオオミジンコ（Daphnia magna）に対する急性遊泳阻害試験

EDI95005

2016/03/08

甲殻類

Daphnia magna

遊泳阻害

EiC50

hours

6.3

mg/L

11 Japan チャレンジプログラム

2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンのオオミジンコ（Daphnia magna）に対する急性遊泳阻害試験

EDI95005

2016/03/08

甲殻類

Daphnia magna

遊泳阻害

EiC50

hours

mg/L

11 Japan チャレンジプログラム

2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンのオオミジンコ（Daphnia magna）に対する急性遊泳阻害試験

EDI95005

2016/03/08

甲殻類

Daphnia magna

遊泳阻害

NOECi

hours

6.3

mg/L

11 Japan チャレンジプログラム

4，4'-イソプロピリデンビス（2，6一ジブロモフェノール）のオオミジンコ（Daphnia magna）に対する急性遊泳阻害試験

9B456G

2016/03/08

甲殻類

Daphnia magna

遊泳阻害

EiC50

hours

9.25

mg/L

11 Japan チャレンジプログラム

4，4'-イソプロピリデンビス（2，6一ジブロモフェノール）のオオミジンコ（Daphnia magna）に対する急性遊泳阻害試験

9B456G

2016/03/08

甲殻類

Daphnia magna

遊泳阻害

EiC100

hours

mg/L

11 Japan チャレンジプログラム

4，4'-イソプロピリデンビス（2，6一ジブロモフェノール）のオオミジンコ（Daphnia magna）に対する急性遊泳阻害試験

9B456G

2016/03/08

甲殻類

Daphnia magna

遊泳阻害

NOECi

hours

mg/L

11 Japan チャレンジプログラム

2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンのオオミジンコ（Daphnia magna）に対する急性遊泳阻害試験

EDI95005

2016/03/08

甲殻類

Daphnia magna

EC50

hours

0.96

mg/L

4 OECD SIDS (HPVC)

2016/02/19

甲殻類

Mysidopsis bahia

Mortality

LC50

hours

860

μg/L

19 その他

IPCS

Environmental health criteria 172, Tetrabromobisphenol A and derivatives

Geneva, World Health Organization

2021/04/13

甲殻類

Acartia tonsa

Mortality

LC75

hours

0.39394

mg/L

0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Crassostrea virginica

Shell deposition

NOEC

hours

6.2

AI μg/L

<3.3 AI ug/L / <3.3 AI ug/L / 18 (14-21) AI ug/L /

16 ECOTOX

Great Lakes Chemical Corp.

Acute Toxicity of Tetrabromobisphenol A to Eastern Oysters (Crassostrea virginica) Under Flow-Through Conditions with Cover Letters Dated 021489 and 021789

EPA/OTS 40-8998102

2020/11/12

甲殻類

Crassostrea virginica

Shell deposition

NOEC

hours

2.6

AI μg/L

<3.3 AI ug/L / <3.3 AI ug/L / 18 (14-21) AI ug/L /

16 ECOTOX

Great Lakes Chemical Corp.

Acute Toxicity of Tetrabromobisphenol A to Eastern Oysters (Crassostrea virginica) Under Flow-Through Conditions with Cover Letters Dated 021489 and 021789

EPA/OTS 40-8998102

2020/11/12

甲殻類

Daphnia magna

Immobile

EC50

hours

>0.9～1.2

μg/L

16 ECOTOX

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2)

2020/11/12

甲殻類

Acartia tonsa

Mortality

LC25

hours

0.15662

mg/L

0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Daphnia magna

Mortality

LC50

hours

1.336

mg/L

0 mg/L / 0 mg/L / 0.05 mg/L / 0.1 mg/L / 0.2 mg/L

16 ECOTOX

Yang,S.W., Z.G. Yan, F.F. Xu, S.R. Wang, and F.C. Wu

Development of Freshwater Aquatic Life Criteria for Tetrabromobisphenol A in China

Environ. Pollut.169

2020/11/12

甲殻類

Acartia tonsa

Mortality

LC50

hours

0.30453

mg/L

0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Daphnia magna

Mortality

LC50

hours

3.21

mg/L

0 mg/L / 0 mg/L / 0.32 mg/L / 0.56 mg/L / 1.00 mg/

16 ECOTOX

Great Lakes Chemical Corp.

Acute Toxicity of FMBP4A (Tetrabromobisphenol A) to the Water Flea Daphnia magna Straus

EPA/OTS 878216112

2020/11/12

甲殻類

Acartia tonsa

Survival

NOEC

hours

200

μg/L

0 ug/L / 2 ug/L / 5 ug/L / 13 ug/L / 32 ug/L / 80

16 ECOTOX

Wollenberger,L., L. Dinan, and M. Breitholtz

Brominated Flame Retardants: Activities in a Crustacean Development Test and in an Ecdysteroid Screening Assay

Environ. Toxicol. Chem.24(2)

2020/11/12

甲殻類

Acartia tonsa

Mortality

LC75

hours

0.30413

mg/L

0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Daphnia magna

Immobile

EC50

hours

0.45

mg/L

0.00 mg/L / 0.04 mg/L / 0.14 mg/L / 0.32 mg/L / 0.

16 ECOTOX

He,Q., X. Wang, P. Sun, Z. Wang, and L. Wang

Acute and Chronic Toxicity of Tetrabromobisphenol A to Three Aquatic Species Under Different pH Conditions

Aquat. Toxicol.164

2020/11/12

甲殻類

Acartia tonsa

Mortality

LC90

hours

0.50074

mg/L

0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Acartia tonsa

Development//Slowed, Retarded, Delayed or Non-development

EC10

hours

12.7

μg/L

0 ug/L / 2 ug/L / 5 ug/L / 13 ug/L / 32 ug/L / 80

16 ECOTOX

Wollenberger,L., L. Dinan, and M. Breitholtz

Brominated Flame Retardants: Activities in a Crustacean Development Test and in an Ecdysteroid Screening Assay

Environ. Toxicol. Chem.24(2)

2020/11/12

甲殻類

Acartia tonsa

Mortality

LC90

hours

0.38778

mg/L

0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Acartia tonsa

Development//Slowed, Retarded, Delayed or Non-development

EC50

hours

125

μg/L

0 ug/L / 2 ug/L / 5 ug/L / 13 ug/L / 32 ug/L / 80

16 ECOTOX

Wollenberger,L., L. Dinan, and M. Breitholtz

Brominated Flame Retardants: Activities in a Crustacean Development Test and in an Ecdysteroid Screening Assay

Environ. Toxicol. Chem.24(2)

2020/11/12

甲殻類

Acartia tonsa

Mortality

NOEC

hours

200

μg/L

0 ug/L / 2 ug/L / 5 ug/L / 13 ug/L / 32 ug/L / 80

16 ECOTOX

Wollenberger,L., L. Dinan, and M. Breitholtz

Brominated Flame Retardants: Activities in a Crustacean Development Test and in an Ecdysteroid Screening Assay

Environ. Toxicol. Chem.24(2)

2020/11/12

甲殻類

Acartia tonsa

Mortality

LC50

hours

0.2112

mg/L

0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Daphnia magna

Immobile

EC50

hours

2.7

mg/L

0.00 mg/L / 2.00 mg/L / 2.50 mg/L / 3.50 mg/L / 5.

16 ECOTOX

He,Q., X. Wang, P. Sun, Z. Wang, and L. Wang

Acute and Chronic Toxicity of Tetrabromobisphenol A to Three Aquatic Species Under Different pH Conditions

Aquat. Toxicol.164

2020/11/12

甲殻類

Crassostrea virginica

Shell deposition

EC50

0.098

mg/L

0.018-0.15 mg/L

19 その他

IPCS

Environmental health criteria 172, Tetrabromobisphenol A and derivatives

Geneva, World Health Organization

2021/04/13

甲殻類

Daphnia magna

Mortality

LC50

hours

0.96

mg/L

19 その他

IPCS

Environmental health criteria 172, Tetrabromobisphenol A and derivatives

Geneva, World Health Organization

2021/04/13

甲殻類

Mysidopsis bahia

Mortality

LC50

hours

1100

μg/L

19 その他

IPCS

Environmental health criteria 172, Tetrabromobisphenol A and derivatives

Geneva, World Health Organization

2021/04/13

甲殻類

Mysidopsis bahia

Mortality

LC50

hours

1200

μg/L

19 その他

IPCS

Environmental health criteria 172, Tetrabromobisphenol A and derivatives

Geneva, World Health Organization

2021/04/13

甲殻類

Daphnia magna

Immobile

EC50

hours

25.33

mg/L

0.00 mg/L / 10.00 mg/L / 15.00 mg/L / 20.00 mg/L /

16 ECOTOX

He,Q., X. Wang, P. Sun, Z. Wang, and L. Wang

Acute and Chronic Toxicity of Tetrabromobisphenol A to Three Aquatic Species Under Different pH Conditions

Aquat. Toxicol.164

2020/11/12

甲殻類

Crassostrea virginica

Shell deposition

NOEC

0.018

mg/L

0.018-0.15 mg/L

19 その他

IPCS

Environmental health criteria 172, Tetrabromobisphenol A and derivatives

Geneva, World Health Organization

2021/04/13

甲殻類

Crassostrea virginica

Shell deposition

EC50

hours

120

AI μg/L

0 AI ug/L / 0 AI ug/L / 75 AI ug/L / 100 AI ug/L /

16 ECOTOX

Great Lakes Chemical Corp.

Acute Toxicity of Tetrabromobisphenol A to Eastern Oysters (Crassostrea virginica) Under Flow-Through Conditions with Cover Letters Dated 021489 and 021789

EPA/OTS 40-8998102

2020/11/12

甲殻類

Acartia tonsa

Mortality

LC10

hours

0.04982

mg/L

0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Daphnia magna

Immobile

EC50

hours

0.6

mg/L

0 mg/L / 0 mg/L / 0.07 mg/L / 0.09 mg/L / 0.24 mg/

16 ECOTOX

Waaijers,S.L., J. Hartmann, A.M. Soeter, R. Helmus, S.A.E. Kools, P. De Voogt, W. Admiraal, J.R. Parsons, and M.H.S. Kr

Toxicity of New Generation Flame Retardants to Daphnia magna

Sci. Total Environ.463

2020/11/12

甲殻類

Daphnia magna

Immobile

EC50

hours

3.97

mg/L

0.00 mg/L / 0.40 mg/L / 3.20 mg/L / 5.00 mg/L / 6.

16 ECOTOX

He,Q., X. Wang, P. Sun, Z. Wang, and L. Wang

Acute and Chronic Toxicity of Tetrabromobisphenol A to Three Aquatic Species Under Different pH Conditions

Aquat. Toxicol.164

2020/11/12

甲殻類

Daphnia magna

Immobile

EC50

hours

>0.9～1.2

μg/L

16 ECOTOX

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2)

2020/11/12

甲殻類

Daphnia magna

Immobile

EC50

hours

11.54

mg/L

0.00 mg/L / 4.00 mg/L / 6.00 mg/L / 8.00 mg/L / 10

16 ECOTOX

He,Q., X. Wang, P. Sun, Z. Wang, and L. Wang

Acute and Chronic Toxicity of Tetrabromobisphenol A to Three Aquatic Species Under Different pH Conditions

Aquat. Toxicol.164

2020/11/12

甲殻類

Daphnia magna

Immobile

EC50

hours

0.817

mg/L

0.00 mg/L / 0.20 mg/L / 0.50 mg/L / 0.80 mg/L / 1.

16 ECOTOX

He,Q., X. Wang, P. Sun, Z. Wang, and L. Wang

Acute and Chronic Toxicity of Tetrabromobisphenol A to Three Aquatic Species Under Different pH Conditions

Aquat. Toxicol.164

2020/11/12

甲殻類

Daphnia magna

Immobile

EC50

hours

17.34

mg/L

0.00 mg/L / 8.00 mg/L / 12.00 mg/L / 16.00 mg/L /

16 ECOTOX

He,Q., X. Wang, P. Sun, Z. Wang, and L. Wang

Acute and Chronic Toxicity of Tetrabromobisphenol A to Three Aquatic Species Under Different pH Conditions

Aquat. Toxicol.164

2020/11/12

甲殻類

Daphnia magna

Immobile

EC50

hours

0.31

mg/L

0.00 mg/L / 0.15 mg/L / 0.16 mg/L / 0.20 mg/L / 0.

16 ECOTOX

He,Q., X. Wang, P. Sun, Z. Wang, and L. Wang

Acute and Chronic Toxicity of Tetrabromobisphenol A to Three Aquatic Species Under Different pH Conditions

Aquat. Toxicol.164

2020/11/12

甲殻類

Acartia tonsa

Mortality

LC25

hours

0.11826

mg/L

0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Daphnia magna

Immobile

EC50

hours

8.63

mg/L

0.00 mg/L / 5.00 mg/L / 7.00 mg/L / 8.00 mg/L / 9.

16 ECOTOX

He,Q., X. Wang, P. Sun, Z. Wang, and L. Wang

Acute and Chronic Toxicity of Tetrabromobisphenol A to Three Aquatic Species Under Different pH Conditions

Aquat. Toxicol.164

2020/11/12

甲殻類

Acartia tonsa

Development//Slowed, Retarded, Delayed or Non-development

LOEC

hours

200

μg/L

0 ug/L / 2 ug/L / 5 ug/L / 13 ug/L / 32 ug/L / 80

16 ECOTOX

Wollenberger,L., L. Dinan, and M. Breitholtz

Brominated Flame Retardants: Activities in a Crustacean Development Test and in an Ecdysteroid Screening Assay

Environ. Toxicol. Chem.24(2)

2020/11/12

甲殻類

Acartia tonsa

Mortality

LC10

hours

0.03461

mg/L

0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Daphnia magna

Mortality

LOEC

hours

0.56

mg/L

0 mg/L / 0 mg/L / 0.32 mg/L / 0.56 mg/L / 1.00 mg/

16 ECOTOX

Great Lakes Chemical Corp.

Acute Toxicity of FMBP4A (Tetrabromobisphenol A) to the Water Flea Daphnia magna Straus

EPA/OTS 878216112

2020/11/12

甲殻類

Acartia tonsa

Mortality

LC95

hours

0.56466

mg/L

0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Acartia tonsa

Mortality

LC95

hours

0.43784

mg/L

0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Daphnia magna

Immobile

EC50

hours

>0.9～1.2

μg/L

16 ECOTOX

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2)

2020/11/12

甲殻類

Daphnia magna

Immobile

EC50

hours

18.29

mg/L

0.00 mg/L / 10.00 mg/L / 12.00 mg/L / 14.00 mg/L /

16 ECOTOX

He,Q., X. Wang, P. Sun, Z. Wang, and L. Wang

Acute and Chronic Toxicity of Tetrabromobisphenol A to Three Aquatic Species Under Different pH Conditions

Aquat. Toxicol.164

2020/11/12

甲殻類

Daphnia magna

Immobile

EC50

hours

>0.9～1.2

μg/L

16 ECOTOX

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2)

2020/11/12

甲殻類

Acartia tonsa

Mortality

LC99

hours

0.53174

mg/L

0 mg/L / 0 mg/L / 0.0312 mg/L / 0.0625 mg/L / 0.12

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Daphnia magna

NOEC

hours

1.8

mg/L

19 その他

Wildlife International

Tetrabromobisphenol A: A 48-hour flow-through acute toxicity test with the cladoceran (Daphnia magna).

Wildlife International Ltd., Project Number 439A-124 [cited in EU RAR 2008].

2021/04/14

甲殻類

Acartia tonsa

Mortality

LC50

hours

0.4

mg/L

19 その他

Wollenberger L, Dinan L and Breitholtz M

Brominated flame retardants: Activities in a crustacean development test and in an ecdysteroid screening assay.

Environ. Toxicol. Chem. 24

2021/04/14

甲殻類

Acartia tonsa

Development//Slowed, Retarded, Delayed or Non-development

NOEC

hours

μg/L

0 ug/L / 2 ug/L / 5 ug/L / 13 ug/L / 32 ug/L / 80

16 ECOTOX

Wollenberger,L., L. Dinan, and M. Breitholtz

Brominated Flame Retardants: Activities in a Crustacean Development Test and in an Ecdysteroid Screening Assay

Environ. Toxicol. Chem.24(2)

2020/11/12

甲殻類

Daphnia magna

EC50

hours

0.6

mg/L

19 その他

Waaijers SL, Hartmann J, Soeter AM, Helmus R, Kools SAE, de Voogt P, Admiraal W, Parsons JR and Kraak MHS

Toxicity of new generation flame retardants to Daphnia magna

Science of The Total Environment

2021/05/14

甲殻類

Crassostrea virginica

EC50

hours

0.02～0.21

mg/L

19 その他

Brominated Flame Retardants Industry Panel

Acute toxicity of tetrabromobisphenol A to Eastern oysters (Crassostrea virginica) under flow-through conditions.

Springborn Life Sciences, Inc. Report #89-1-2898, Study #1199-0688-6106-504. February 15, 1989.

2021/04/14

甲殻類

Mysidopsis bahia

mortality

LC50

hours

0.86

mg/L

9 ECETOC Aquatic Toxicity, EAT

Goodman LR, Cripe GM, Moody PH, Halsell DG

Acute toxicity of malathion, tetrabromobisphenol-A and tributyltin chloride to mysids (Mysidopsis bahia) of three ages

Bull Environ Contam Toxicol 41

2020/12/23

甲殻類

Mysidopsis bahia

mortality

LC50

hours

0.86

mg/L

9 ECETOC Aquatic Toxicity, EAT

Goodman LR, Cripe GM, Moody PH, Halsell DG

Acute toxicity of malathion, tetrabromobisphenol-A and tributyltin chloride to mysids (Mysidopsis bahia) of three ages

Bull Environ Contam Toxicol 41

2020/12/23

甲殻類

Mysidopsis bahia

mortality

LC50

hours

1.1

mg/L

9 ECETOC Aquatic Toxicity, EAT

Goodman LR, Cripe GM, Moody PH, Halsell DG

Acute toxicity of malathion, tetrabromobisphenol-A and tributyltin chloride to mysids (Mysidopsis bahia) of three ages

Bull Environ Contam Toxicol 41

2020/12/23

甲殻類

Mysidopsis bahia

mortality

LC50

hours

1.2

mg/L

9 ECETOC Aquatic Toxicity, EAT

Goodman LR, Cripe GM, Moody PH, Halsell DG

Acute toxicity of malathion, tetrabromobisphenol-A and tributyltin chloride to mysids (Mysidopsis bahia) of three ages

Bull Environ Contam Toxicol 41

2020/12/23

甲殻類

Acartia tonsa

Larval development rate

EC50

days

125

μg/L

2, 5, 13, 32, 80,200 μg/l, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Wollenberger L., Dinan L. and Breitholtz M.

Brominated flame retardants: Activities in a crustacean development test and in an ecdysteroid screening assay.

Environ. Toxicol. Chem., 24

2005

2019/12/27

甲殻類

Chironomus riparius

Mean development time

NOEC

days

125

mg/kg dry wt.

63, 125, 250, 500, 1000 mg/kg, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Wildlife International

Tetrabromobisphenol-A (TBBPA): A 28-day sediment toxicity test with Chironomus riparius using spiked sediment.

Wildlife International Ltd., Project Number 439A-130.

2005

2019/12/27

甲殻類

Chironomus yoshimatsui

羽化個体数

EC50

days

870

mg/kg-dry wt

○

対照区，助剤対照区，56, 100, 180, 320, 560, 1000mg/kg-dry wt

58.1, 101, 191, 364, 618, 1120mg/kg-dry wt

1 日本環境省　生態リスク初期評価

2020/01/14

甲殻類

Daphnia magna

NOEC

days

0.3

mg/L

4 OECD SIDS (HPVC)

2020/01/17

甲殻類

Chironomus riparius

Mean emergence ratios

NOEC

days

125

mg/kg dry wt.

63, 125, 250, 500, 1000 mg/kg, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Wildlife International

Tetrabromobisphenol-A (TBBPA): A 28-day sediment toxicity test with Chironomus riparius using spiked sediment.

Wildlife International Ltd., Project Number 439A-130.

2005

2019/12/27

甲殻類

Chironomus riparius

％ Emerged

EC50

days

235

mg/kg dry wt.

63, 125, 250, 500, 1000 mg/kg, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Wildlife International

Tetrabromobisphenol-A (TBBPA): A 28-day sediment toxicity test with Chironomus riparius using spiked sediment.

Wildlife International Ltd., Project Number 439A-130.

2005

2019/12/27

甲殻類

Daphnia magna

Reproduction

EC50

days

1.66

mg/L

○

対照区，助剤対照区，0.08, 0.25, 0.80, 2.50, 8.00mg/l

0.08, 0.24, 0.86, 2.69, 9.39mg/l

1 日本環境省　生態リスク初期評価

2020/01/10

甲殻類

Chironomus riparius

Abnormal behaviour

NOEC

days

125

mg/kg dry wt.

63, 125, 250, 500, 1000 mg/kg, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Wildlife International

Tetrabromobisphenol-A (TBBPA): A 28-day sediment toxicity test with Chironomus riparius using spiked sediment.

Wildlife International Ltd., Project Number 439A-130.

2005

2019/12/27

甲殻類

Mytilus edulis

Specific growth rate-shell length

NOEC

days

μg/L

17, 32, 62, 126, 226 μg/l, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Brown R. J., Smyth D. V. and Kent S. J.

TBBPA: Determination of effects on the growth of the common mussel Mytilus edulis.

Brixham Environmental Laboratory Study Number 03-0337/A. Study sponsored by ACC-BFRIP, Arlington, USA.

2005

2019/12/27

甲殻類

Daphnia magna

Reproduction

NOEC

days

0.8

mg/L

○

対照区，助剤対照区，0.08, 0.25, 0.80, 2.50, 8.00mg/l

0.08, 0.24, 0.86, 2.69, 9.39mg/l

1 日本環境省　生態リスク初期評価

2020/01/10

甲殻類

Chironomus yoshimatsui

変態速度

EC50

days

>1140

mg/kg-dry wt

○

対照区，助剤対照区，56, 100, 180, 320, 560, 1000mg/kg-dry wt

58.1, 101, 191, 364, 618, 1120mg/kg-dry wt

1 日本環境省　生態リスク初期評価

2020/01/14

甲殻類

Daphnia magna

Reproduction

LOEC

days

980

μg/L

○

5.6, 100, 190, 300, 980µg/l

14 BUA Report

Great Lakes Chemical Corporation

The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions. Springborn Laboratories, SLS Report: 89-1-2925

1989

2020/01/21

甲殻類

Chironomus yoshimatsui

NOEC

days

360

mg/kg-dry wt

○

対照区，助剤対照区，56, 100, 180, 320, 560, 1000mg/kg-dry wt

58.1, 101, 191, 364, 618, 1120mg/kg-dry wt

1 日本環境省　生態リスク初期評価

2020/01/14

甲殻類

Chironomus yoshimatsui

LOEC

days

610

mg/kg-dry wt

○

対照区，助剤対照区，56, 100, 180, 320, 560, 1000mg/kg-dry wt

58.1, 101, 191, 364, 618, 1120mg/kg-dry wt

1 日本環境省　生態リスク初期評価

2020/01/14

甲殻類

Daphnia magna

Mortality

LC50

days

1.74

mg/L

○

対照区，助剤対照区，0.08, 0.25, 0.80, 2.50, 8.00mg/l

0.08, 0.24, 0.86, 2.69, 9.39mg/l

1 日本環境省　生態リスク初期評価

2020/01/10

甲殻類

Chironomus riparius

Mean development rate

NOEC

days

125

mg/kg dry wt.

63, 125, 250, 500, 1000 mg/kg, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Wildlife International

Tetrabromobisphenol-A (TBBPA): A 28-day sediment toxicity test with Chironomus riparius using spiked sediment.

Wildlife International Ltd., Project Number 439A-130.

2005

2019/12/27

甲殻類

Daphnia magna

Reproduction

NOEC

days

0.8

mg/L

0, 0.08, 0.25, 0.80, 2.50, 8.00mg/l

設定値の88～118％（換水直後)、88～117％（換水直前）

18 既存化学物質安全性(ハザード)評価シート

環境省

既存化学物質審査シート（三監No.10）

2020/01/08

甲殻類

Acartia tonsa

Larval development rate

EC10

days

12.7

μg/L

2, 5, 13, 32, 80,200 μg/l, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Wollenberger L., Dinan L. and Breitholtz M.

Brominated flame retardants: Activities in a crustacean development test and in an ecdysteroid screening assay.

Environ. Toxicol. Chem., 24

2005

2019/12/27

甲殻類

Acartia tonsa

Larval development

EC50

120

hours

125

μg/L

14 BUA Report

Breitholtz M, Wollenberger L, Bengtsson BE, Kusk OK

Impacts of brominated flame retardants on development and reproduction of two copepod species, Nitocra spinipes and Acartia tonsa.

The Second International Workshop on Brominated Flame Retardants, May 14-16, 2001, Stockholm, Sweden, abstract volume

2001

2020/01/22

甲殻類

Acartia tonsa

NOEC

days

0.0127

mg/L

4 OECD SIDS (HPVC)

2020/01/17

甲殻類

Mytilus edulis

Specific growth rate-wet tissue weight

NOEC

days

μg/L

17, 32, 62, 126, 226 μg/l, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Brown R. J., Smyth D. V. and Kent S. J.

TBBPA: Determination of effects on the growth of the common mussel Mytilus edulis.

Brixham Environmental Laboratory Study Number 03-0337/A. Study sponsored by ACC-BFRIP, Arlington, USA.

2005

2019/12/27

甲殻類

Mytilus edulis

Specific growth rate-dry tissue weight

NOEC

days

μg/L

17, 32, 62, 126, 226 μg/l, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Brown R. J., Smyth D. V. and Kent S. J.

TBBPA: Determination of effects on the growth of the common mussel Mytilus edulis.

Brixham Environmental Laboratory Study Number 03-0337/A. Study sponsored by ACC-BFRIP, Arlington, USA.

2005

2019/12/27

甲殻類

Mytilus edulis

Mortality

NOEC

days

>=226

μg/L

17, 32, 62, 126, 226 μg/l, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Brown R. J., Smyth D. V. and Kent S. J.

TBBPA: Determination of effects on the growth of the common mussel Mytilus edulis.

Brixham Environmental Laboratory Study Number 03-0337/A. Study sponsored by ACC-BFRIP, Arlington, USA.

2005

2019/12/27

甲殻類

Nitocra spinipes

Larval development rate, fecundity, sex ratio

NOEC

days

>=0.035

mg/L

Up to 0.035mg/l

7 EU Risk Assessment Report (EUリスク評価書）

Wollenberger L., Dinan L. and Breitholtz M.

Effects of brominated flame retardants on two marine copepod species, Acartia tonsa and Nitocra spinipes, and on the Ecdysterodresponsive Drosophila malanogaster BII-cell-line.

Organohalogen Compounds, 57

2002

2019/12/25

甲殻類

Mytilus edulis

NOEC

days

0.017

mg/L

4 OECD SIDS (HPVC)

2020/01/17

甲殻類

Daphnia magna

Repro.

NOEC

days

0.3

mg/L

0.056, 0.10, 0.19, 0.30, 0.98mg/l, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Laboratories

The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions.

Report No 89-01-2925. Springborn Laboratories, Inc., Wareham, Massachusetts

1989

2019/12/27

甲殻類

Daphnia magna

Reproduction

NOEC

days

800

μg/L

6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）

環境庁

平成11年度　生態影響試験実施事業報告

2000

2020/02/14

甲殻類

Acartia tonsa

growth

EC10

days

12.7

μg/L

2, 5, 13, 32, 80, 200 µg/L

12 ECHA Information on Registered Substances

Wollenberger L, Dinan L & Breitholtz M

BROMINATED FLAME RETARDANTS: ACTIVITIES IN A CRUSTACEAN DEVELOPMENT TEST AND IN AN ECDYSTEROID SCREENING ASSAY

Environ. Toxicol. Chem. 24

2005

甲殻類

Acartia tonsa

Larval development rate

EC50

days

0.125

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Breitholtz M., Wollenberger L., Bengtsson B-E. and Kusk K. O.

Impact of brominated flame retardants on development and reproduction of two copepod species, Nitocra spinipes and Acartia tonsa.

Second International Workshop on Brominated Flame Retardants, May 14-16, Stockholm University, Sweden

2001

2019/12/25

甲殻類

Daphnia magna

Reproduction

LOEC

days

2.5

mg/L

○

対照区，助剤対照区，0.08, 0.25, 0.80, 2.50, 8.00mg/l

0.08, 0.24, 0.86, 2.69, 9.39mg/l

1 日本環境省　生態リスク初期評価

2020/01/10

甲殻類

Daphnia magna

Growth

NOEC

days

>=0.98

mg/L

0.056, 0.10, 0.19, 0.30, 0.98mg/l, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Laboratories

The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions.

Report No 89-01-2925. Springborn Laboratories, Inc., Wareham, Massachusetts

1989

2019/12/27

甲殻類

Daphnia magna

Reproduction

NOEC

days

300

μg/L

○

5.6, 100, 190, 300, 980µg/l

14 BUA Report

Great Lakes Chemical Corporation

The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions. Springborn Laboratories, SLS Report: 89-1-2925

1989

2020/01/21

甲殻類

Daphnia magna

Mortality

NOEC

days

>=0.98

mg/L

0.056, 0.10, 0.19, 0.30, 0.98mg/l, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Laboratories

The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions.

Report No 89-01-2925. Springborn Laboratories, Inc., Wareham, Massachusetts

1989

2019/12/27

甲殻類

Acartia tonsa

growth

EC50

days

125

μg/L

2, 5, 13, 32, 80, 200 µg/L

12 ECHA Information on Registered Substances

Wollenberger L, Dinan L & Breitholtz M

BROMINATED FLAME RETARDANTS: ACTIVITIES IN A CRUSTACEAN DEVELOPMENT TEST AND IN AN ECDYSTEROID SCREENING ASSAY

Environ. Toxicol. Chem. 24

2005

甲殻類

Daphnia magna

reproduction

MATC

days

>0.3～<0.98

mg/L

○

0.13, 0.25, 0.5, 1.0, 2.0 mg/L

0.037 - 0.078, 0.068 - 0.13, 0.14 - 0.26, 0.19 - 0.29, 0.65 - 1.3 mg/L

12 ECHA Information on Registered Substances

study report

1989

甲殻類

Daphnia magna

mortality

EC50

days

>0.96

mg/L

○

0.13, 0.25, 0.5, 1.0, 2.0 mg/L

0.037 - 0.078, 0.068 - 0.13, 0.14 - 0.26, 0.19 - 0.29, 0.65 - 1.3 mg/L

12 ECHA Information on Registered Substances

study report

1989

甲殻類

Mytilus edulis

growth

NOEC

days

μg/L

○

19, 38, 75, 150, 300 µg/L

17, 32, 62, 126, 226 µg/L

12 ECHA Information on Registered Substances

study report

2005

甲殻類

Daphnia magna

reproduction

NOEC

days

0.38

mg/L

○

0.13, 0.25, 0.5, 1.0, 2.0 mg/L

0.037 - 0.078, 0.068 - 0.13, 0.14 - 0.26, 0.19 - 0.29, 0.65 - 1.3 mg/L

12 ECHA Information on Registered Substances

study report

1989

甲殻類

Daphnia magna

reproduction

NOEC

days

0.38

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

reproduction

MATC

days

>0.3～<0.98

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

mortality

EC50

days

>0.96

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

甲殻類

Daphnia magna

EC50

days

1.7

mg/L

1 日本環境省　生態リスク初期評価

環境省

（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）

2016/11/10

甲殻類

Daphnia magna

NOEC

days

0.8

mg/L

1 日本環境省　生態リスク初期評価

環境省

（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）

2016/11/09

甲殻類

Daphnia magna

immobility

NOEC

hours

>=1.8

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Wildlife International

Tetrabromobisphenol A: A 48-hour flow-through acute toxicity test with the cladoceran (Daphnia magna).

Wildlife International Ltd., Project Number 439A-124. Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

2003

2016/03/04

甲殻類

Daphnia magna

NOEC

days

0.3

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Laboratories

The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions.

Report No 89-01-2925. Springborn Laboratories, Inc., Wareham, Massachusetts.

1989

2016/03/04

甲殻類

Daphnia magna

Mortality

NOEC

days

>=0.98

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Laboratories

The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions.

Report No 89-01-2925. Springborn Laboratories, Inc., Wareham, Massachusetts.

1989

2016/03/04

甲殻類

Daphnia magna

繁殖

EC50

days

1.66

mg/L

11 Japan チャレンジプログラム

4，4’-イソプロピリデンビス（2，6-ジブロモフェノール）のオオミジンコ（Daphnia magna)に対する繁殖阻害試験

9B478G

2016/03/08

甲殻類

Daphnia magna

Reproduction

NOEC

days

800

μg/L

6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）

環境庁

平成 11 年度　生態影響試験実施事業報告

2000

2016/03/05

甲殻類

Daphnia magna

Growth

NOEC

days

>=0.98

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Laboratories

The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions.

Report No 89-01-2925. Springborn Laboratories, Inc., Wareham, Massachusetts.

1989

2016/03/04

甲殻類

Daphnia magna

繁殖

LOEC

days

2.5

mg/L

11 Japan チャレンジプログラム

4，4’-イソプロピリデンビス（2，6-ジブロモフェノール）のオオミジンコ（Daphnia magna)に対する繁殖阻害試験

9B478G

2016/03/08

甲殻類

Daphnia magna

繁殖

LOECr

days

0.42

mg/L

11 Japan チャレンジプログラム

2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンのオオミジンコ（Daphnia magna)に対する繁殖阻害試験

EDR95005

2016/03/08

甲殻類

Daphnia magna

繁殖

NOEC

days

0.8

mg/L

11 Japan チャレンジプログラム

4，4’-イソプロピリデンビス（2，6-ジブロモフェノール）のオオミジンコ（Daphnia magna)に対する繁殖阻害試験

9B478G

2016/03/08

甲殻類

Daphnia magna

繁殖

NOECr

days

<0.42

mg/L

11 Japan チャレンジプログラム

2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンのオオミジンコ（Daphnia magna)に対する繁殖阻害試験

EDR95005

2016/03/08

甲殻類

Daphnia magna

body lengths, Reproduction, mortality

days

>0.3～<0.98

10 EHC (Environmental Health Criteria)

Surprenant DC

The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions.

Massachusetts, Springborn Life Sciences, Inc. (Report No. 89-01-2925 submitted to WHO by the Brominated Flame Retardant Industry Panel).

1989

2016/03/04

甲殻類

Daphnia magna

body lengths, Reproduction, mortality

days

>0.3～<0.98

10 EHC (Environmental Health Criteria)

Surprenant DC

The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions.

Massachusetts, Springborn Life Sciences, Inc. (Report No. 89-01-2925 submitted to WHO by the Brominated Flame Retardant Industry Panel).

1989

2016/03/04

甲殻類

Daphnia magna

親ミジンコの死亡

LC50

days

1.74

mg/L

11 Japan チャレンジプログラム

4，4’-イソプロピリデンビス（2，6-ジブロモフェノール）のオオミジンコ（Daphnia magna)に対する繁殖阻害試験

9B478G

2016/03/08

甲殻類

Daphnia magna

親ミジンコの死亡

LC50

days

3.9

mg/L

11 Japan チャレンジプログラム

2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンのオオミジンコ（Daphnia magna)に対する繁殖阻害試験

EDR95005

2016/03/08

甲殻類

Daphnia magna

繁殖

ErC50

days

0.82

mg/L

11 Japan チャレンジプログラム

2，2一ビス［4一ヒドロキシー3，5一ジブロモフェニル］プロパンのオオミジンコ（Daphnia magna)に対する繁殖阻害試験

EDR95005

2016/03/08

甲殻類

Daphnia magna

NOEC

days

0.3

mg/L

4 OECD SIDS (HPVC)

2016/02/19

甲殻類

Daphnia magna

Mortality

LC50

days

0.056～0.98

mg/L

19 その他

IPCS

Environmental health criteria 172, Tetrabromobisphenol A and derivatives

Geneva, World Health Organization

2021/04/13

甲殻類

Daphnia magna

Immobile

EC50

days

0.98

mg/L

<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg

16 ECOTOX

Great Lakes Chemical Corp.

The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989

EPA/OTS 40-8998117

2020/11/12

甲殻類

Chironomus riparius

Sediment ratio, development rate, development time

NOEC

days

125

mg/kg dw [TBBPA]

19 その他

[ACCBFRIP] American Chemistry Council Brominated Flame Retardant Industry Panel

Tetrabromobisphenol-A (TBBPA): A 28-day sediment toxicity test with Chironomus riparius using spiked sediment.

Wildlife International, Ltd. Project Number: 439A-130. July 12, 2005

2021/05/14

甲殻類

Daphnia magna

Reproduction

NOEC

days

0.98

mg/L

<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg

16 ECOTOX

Great Lakes Chemical Corp.

The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989

EPA/OTS 40-8998117

2020/11/12

甲殻類

Daphnia magna

Reproduction

EC10

days

0.016

mg/L

0 mg/L / 0 mg/L / 0.03 mg/L / 0.04 mg/L / 0.05 mg/

16 ECOTOX

Yang,S.W., Z.G. Yan, F.F. Xu, S.R. Wang, and F.C. Wu

Development of Freshwater Aquatic Life Criteria for Tetrabromobisphenol A in China

Environ. Pollut.169

2020/11/12

甲殻類

Daphnia magna

Mortality//Lifespan

EC10

days

0.047

mg/L

0 mg/L / 0 mg/L / 0.03 mg/L / 0.04 mg/L / 0.05 mg/

16 ECOTOX

Yang,S.W., Z.G. Yan, F.F. Xu, S.R. Wang, and F.C. Wu

Development of Freshwater Aquatic Life Criteria for Tetrabromobisphenol A in China

Environ. Pollut.169

2020/11/12

甲殻類

Acartia tonsa

Reproduction

EC20

days

μg/L

0 ug/L / 23 ug/L / 47 ug/L / 94 ug/L / 188 ug/L

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Daphnia magna

Survival

NOEC

days

0.98

mg/L

<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg

16 ECOTOX

Great Lakes Chemical Corp.

The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989

EPA/OTS 40-8998117

2020/11/12

甲殻類

Acartia tonsa

Reproduction

EC10

days

μg/L

0 ug/L / 23 ug/L / 47 ug/L / 94 ug/L / 188 ug/L

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Daphnia magna

Reproduction

MATC

days

0.54

mg/L

<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg

16 ECOTOX

Great Lakes Chemical Corp.

The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989

EPA/OTS 40-8998117

2020/11/12

甲殻類

Acartia tonsa

Reproduction

EC20

days

μg/L

0 ug/L / 23 ug/L / 47 ug/L / 94 ug/L / 188 ug/L

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Acartia tonsa

Reproduction

EC50

days

267

μg/L

0 ug/L / 23 ug/L / 47 ug/L / 94 ug/L / 188 ug/L

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Daphnia magna

Reproduction

NOEC

days

0.98

mg/L

<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg

16 ECOTOX

Great Lakes Chemical Corp.

The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989

EPA/OTS 40-8998117

2020/11/12

甲殻類

Daphnia magna

Reproduction

NOEC

days

0.98

mg/L

<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg

16 ECOTOX

Great Lakes Chemical Corp.

The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989

EPA/OTS 40-8998117

2020/11/12

甲殻類

Daphnia magna

Reproduction

NOEC

days

0.98

mg/L

<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg

16 ECOTOX

Great Lakes Chemical Corp.

The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989

EPA/OTS 40-8998117

2020/11/12

甲殻類

Daphnia magna

Reproduction

NOEC

days

0.98

mg/L

<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg

16 ECOTOX

Great Lakes Chemical Corp.

The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989

EPA/OTS 40-8998117

2020/11/12

甲殻類

Daphnia magna

Reproduction

NOEC

days

0.98

mg/L

<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg

16 ECOTOX

Great Lakes Chemical Corp.

The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989

EPA/OTS 40-8998117

2020/11/12

甲殻類

Daphnia magna

Reproduction(Time to first progeny)

EC10

days

0.084

mg/L

0 mg/L / 0 mg/L / 0.03 mg/L / 0.04 mg/L / 0.05 mg/

16 ECOTOX

Yang,S.W., Z.G. Yan, F.F. Xu, S.R. Wang, and F.C. Wu

Development of Freshwater Aquatic Life Criteria for Tetrabromobisphenol A in China

Environ. Pollut.169

2020/11/12

甲殻類

Acartia tonsa

Reproduction

EC50

days

135

μg/L

0 ug/L / 23 ug/L / 47 ug/L / 94 ug/L / 188 ug/L

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Daphnia magna

LOEC

days

0.98

mg/L

19 その他

Brominated Flame Retardants Industry Panel

The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions.

Springborn Laboratories, Inc. Report #801-2925, Study #1199-1287-6108-130. August 15, 1989.

2021/04/14

甲殻類

Daphnia magna

Reproduction

NOEC

days

0.98

mg/L

<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg

16 ECOTOX

Great Lakes Chemical Corp.

The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989

EPA/OTS 40-8998117

2020/11/12

甲殻類

Acartia tonsa

Reproduction

EC10

days

μg/L

0 ug/L / 23 ug/L / 47 ug/L / 94 ug/L / 188 ug/L

16 ECOTOX

Mariager,L.P.

Effects of Environmental Endocrine Disruptors on a Freshwater and a Marine Crustacean

M.S. Thesis, Aarhus University, Institute of Biological Sciences, Aarhus, Denmark

2020/11/12

甲殻類

Daphnia magna

NOEC

days

0.3

mg/L

19 その他

Brominated Flame Retardants Industry Panel

The chronic toxicity of tetrabromobisphenol A (TBBPA) to Daphnia magna under flow-through conditions.

Springborn Laboratories, Inc. Report #801-2925, Study #1199-1287-6108-130. August 15, 1989.

2021/04/14

甲殻類

Mytilus edulis

Wet tissue weight

LOEC

days

0.126

mg/L

19 その他

[ACCBFRIP] American Chemistry Council Brominated Flame Retardant Industry Panel

Tetrabromobisphenol A: Determination of the effect on the growth of the common mussel (Mytilus edulis).

Analytical phase. Wildlife International, Ltd. Project Number: 439C-143. March 28, 2005

2021/04/14

甲殻類

Daphnia magna

Reproduction

EC10

days

0.139

mg/L

0 mg/L / 0 mg/L / 0.03 mg/L / 0.04 mg/L / 0.05 mg/

16 ECOTOX

Yang,S.W., Z.G. Yan, F.F. Xu, S.R. Wang, and F.C. Wu

Development of Freshwater Aquatic Life Criteria for Tetrabromobisphenol A in China

Environ. Pollut.169

2020/11/12

甲殻類

Chironomus riparius

Emergence ratio, development rate, development time

LOEC

days

250

mg/kg dw

19 その他

[ACCBFRIP] American Chemistry Council Brominated Flame Retardant Industry Panel

Tetrabromobisphenol-A (TBBPA): A 28-day sediment toxicity test with Chironomus riparius using spiked sediment.

Wildlife International, Ltd. Project Number: 439A-130. July 12, 2005

2021/04/14

甲殻類

Mytilus edulis

Shell length

LOEC

days

0.032

mg/L

19 その他

[ACCBFRIP] American Chemistry Council Brominated Flame Retardant Industry Panel

Tetrabromobisphenol A: Determination of the effect on the growth of the common mussel (Mytilus edulis).

Analytical phase. Wildlife International, Ltd. Project Number: 439C-143. March 28, 2005

2021/04/14

甲殻類

Daphnia magna

Survival

NOEC

days

0.98

mg/L

<0.025 mg/L / <0.025 mg/L / 0.056 (0.037-0.078) mg

16 ECOTOX

Great Lakes Chemical Corp.

The Chronic Toxicity of Tetrabromobisphenol A to Daphnia magna Under Flow-Through Conditions (Final Report) with Cover Letter Dated 081989

EPA/OTS 40-8998117

2020/11/12

甲殻類

Daphnia magna

Development//Sexual development

EC10

days

0.039

mg/L

0 mg/L / 0 mg/L / 0.03 mg/L / 0.04 mg/L / 0.05 mg/

16 ECOTOX

Yang,S.W., Z.G. Yan, F.F. Xu, S.R. Wang, and F.C. Wu

Development of Freshwater Aquatic Life Criteria for Tetrabromobisphenol A in China

Environ. Pollut.169

2020/11/12

魚類

Danio rerio (Zebrafish)

MortalityMortality

LOEC LOEC

days

0.4

mg/L [Active ingredient]

0 mg/L / 0.4 mg/L / 0.8 mg/L / 1.6 mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Embryonic Exposure to Tetrabromobisphenol A and Its Metabolites, Bisphenol A and Tetrabromobisphenol A Dimethyl Ether Disrupts Normal Zebrafish (Danio rerio) Development and Matrix Metalloproteinase Expression

Aquat. Toxicol.100(3)

2010

魚類

Danio rerio (Zebrafish)

PhysiologyHeart rate

LOEC LOEC

days

0.4

mg/L [Active ingredient]

0 mg/L / 0.4 mg/L / 0.8 mg/L / 1.6 mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3)

2010

魚類

Danio rerio (Zebrafish)

MortalityMortality

LC50 LC50

days

0.0000036

M [Active ingredient]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Kalasekar,S.M., E. Zacharia, N. Kessler, N.A. Ducharme, J.A. Gustafsson, I.A. Kakadiaris, and M. Bondesson

Identification of Environmental Chemicals that Induce Yolk Malabsorption in Zebrafish Using Automated Image Segmentation

Reprod. Toxicol.55

2015

魚類

Danio rerio (Zebrafish)

PhysiologyHeart rate

LOEC LOEC

hours

1.5

μM [Active ingredient]

0 uM / 0.75 uM / 1.5 uM / 3 uM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3)

2010

魚類

Danio rerio (Zebrafish)

DevelopmentOrgan/tissue formation

NOEC NOEC

days

0.75

μM [Active ingredient]

0 uM / 0.75 uM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3)

2010

魚類

Danio rerio (Zebrafish)

MortalityMortality

hours

2.64

mg/L [Active ingredient]

0 mg/L / 0.53 mg/L / 1.32 mg/L / 2.64 mg/L / 3.95 mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108

2012

魚類

Danio rerio (Zebrafish)

MortalityMortality

hours

1.5

mg/L [Formulation]

0 mg/L / 0.002 mg/L / 0.01 mg/L / 0.05 mg/L / 0.25 mg/L / 0.75 mg/L / 1.5 mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Hu,J., Y. Liang, M. Chen, and X. Wang

Assessing the Toxicity of TBBPA and HBCD by Zebrafish Embryo Toxicity Assay and Biomarker Analysis

Environ. Toxicol.24(4)

2009

魚類

Danio rerio (Zebrafish)

PhysiologyHeart rate

NOEC NOEC

hours

0.75

μM [Active ingredient]

0 uM / 0.75 uM / 1.5 uM / 3 uM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3)

2010

魚類

Danio rerio (Zebrafish)

DevelopmentOrgan/tissue formation

NOEC NOEC

days

0.75

μM [Active ingredient]

0 uM / 0.75 uM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3)

2010

魚類

Danio rerio (Zebrafish)

PhysiologyHeart rate

NOEC NOEC

hours

1.5

μM [Active ingredient]

0 uM / 0.75 uM / 1.5 uM / 3 uM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3)

2010

魚類

Danio rerio (Zebrafish)

GrowthCondition index

LOEC LOEC

days

100

nM [Formulation]

0 nM / 10 nM / 100 nM / 1000 nM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Riu,A., C.W. McCollum, C.L. Pinto, M. Grimaldi, A. Hillenweck, E. Perdu, D. Zalko, L. Bernard, V. Laudet, P. Balaguer,

Halogenated Bisphenol-A Analogs Act as Obesogens in Zebrafish Larvae (Danio rerio)

Toxicol. Sci.139(1)

2014

魚類

Danio rerio (Zebrafish)

DevelopmentOrgan/tissue formation

NOEC NOEC

days

0.75

μM [Active ingredient]

0 uM / 0.75 uM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3)

2010

魚類

Danio rerio (Zebrafish)

MortalityMortality

hours

0.82

mg/L [Active ingredient]

0 mg/L / 0.11 mg/L / 0.27 mg/L / 0.55 mg/L / 0.82 mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108

2012

魚類

Danio rerio (Zebrafish)

InjuryCurvature

LOEC LOEC

days

0.4

mg/L [Active ingredient]

0 mg/L / 0.4 mg/L / 0.8 mg/L / 1.6 mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3)

2010

魚類

Danio rerio (Zebrafish)

PhysiologyHeart rate

LOEC LOEC

hours

μM [Active ingredient]

0 uM / 0.75 uM / 1.5 uM / 3 uM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3)

2010

魚類

Danio rerio (Zebrafish)

DevelopmentYolk sac absorption, Yolk sac utilization

LOEC LOEC

days

0.000001

M [Active ingredient]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Kalasekar,S.M., E. Zacharia, N. Kessler, N.A. Ducharme, J.A. Gustafsson, I.A. Kakadiaris, and M. Bondesson

Identification of Environmental Chemicals that Induce Yolk Malabsorption in Zebrafish Using Automated Image Segmentation

Reprod. Toxicol.55

2015

魚類

Danio rerio (Zebrafish)

DevelopmentYolk sac absorption, Yolk sac utilization

LOEC LOEC

days

1000

nM [Active ingredient]

0 nM / 10 nM / 100 nM / 1000 nM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Kalasekar,S.M., E. Zacharia, N. Kessler, N.A. Ducharme, J.A. Gustafsson, I.A. Kakadiaris, and M. Bondesson

Identification of Environmental Chemicals that Induce Yolk Malabsorption in Zebrafish Using Automated Image Segmentation

Reprod. Toxicol.55

2015

魚類

Danio rerio (Zebrafish)

DevelopmentDeformation

LOEC LOEC

days

0.4

mg/L [Active ingredient]

0 mg/L / 0.4 mg/L / 0.8 mg/L / 1.6 mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3)

2010

魚類

Danio rerio (Zebrafish)

ReproductionHatch

LOEC LOEC

days

0.4

mg/L [Active ingredient]

0 mg/L / 0.4 mg/L / 0.8 mg/L / 1.6 mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3)

2010

魚類

Danio rerio (Zebrafish)

DevelopmentYolk sac absorption, Yolk sac utilization

NOEC NOEC

days

100

nM [Active ingredient]

0 nM / 10 nM / 100 nM / 1000 nM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Kalasekar,S.M., E. Zacharia, N. Kessler, N.A. Ducharme, J.A. Gustafsson, I.A. Kakadiaris, and M. Bondesson

Identification of Environmental Chemicals that Induce Yolk Malabsorption in Zebrafish Using Automated Image Segmentation

Reprod. Toxicol.55

2015

魚類

Danio rerio (Zebrafish)

Survival

NOEC

days

0.4

mg/L

0 mg/L / 0.10 mg/L / 0.40 mg/L / 0.70 mg/L / 1.00

16 ECOTOX

Wu,S., G. Ji, J. Liu, S. Zhang, Y. Gong, and L. Shi

TBBPA Induces Developmental Toxicity, Oxidative Stress, and Apoptosis in Embryos and Zebrafish Larvae (Danio rerio)

Environ. Toxicol.31(10)

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality

LC50

162

hours

1.45

ppm

0 ppm / 1.25 ppm / 2.5 ppm / 5.0 ppm / 10 ppm / 20

16 ECOTOX

Usenko,C.Y., E.L. Abel, A. Hopkins, G. Martinez, J. Tijerina, M. Kudela, N. Norris, L. Joudeh, and E.D. Bruce

Evaluation of Common Use Brominated Flame Retardant (BFR) Toxicity Using a Zebrafish Embryo Model

Toxics4(21)

2020/11/12

魚類

Danio rerio (Zebrafish)

Behavior//Swimming

LOEC

142

hours

100

μg/L

0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Growth(Length)

NOEC

days

0.4

mg/L

0 mg/L / 0.10 mg/L / 0.40 mg/L / 0.70 mg/L / 1.00

16 ECOTOX

Wu,S., G. Ji, J. Liu, S. Zhang, Y. Gong, and L. Shi

TBBPA Induces Developmental Toxicity, Oxidative Stress, and Apoptosis in Embryos and Zebrafish Larvae (Danio rerio)

Environ. Toxicol.31(10)

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality

NR-ZERO

hours

0.82

mg/L

0 mg/L / 0.11 mg/L / 0.27 mg/L / 0.55 mg/L / 0.82

16 ECOTOX

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality

NR-ZERO

hours

2.64

mg/L

0 mg/L / 0.53 mg/L / 1.32 mg/L / 2.64 mg/L / 3.95

16 ECOTOX

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality

NR-LETH

hours

1.5

mg/L

0 mg/L / 0.002 mg/L / 0.01 mg/L / 0.05 mg/L / 0.25

16 ECOTOX

Hu,J., Y. Liang, M. Chen, and X. Wang

Assessing the Toxicity of TBBPA and HBCD by Zebrafish Embryo Toxicity Assay and Biomarker Analysis

Environ. Toxicol.24(4)

2020/11/12

魚類

Danio rerio (Zebrafish)

Survival

NOEC

142

hours

200

μg/L

0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Development//Teratogenic measurements

LOEC

days

0.4

mg/L

0 mg/L / 0.10 mg/L / 0.40 mg/L / 0.70 mg/L / 1.00

16 ECOTOX

Wu,S., G. Ji, J. Liu, S. Zhang, Y. Gong, and L. Shi

TBBPA Induces Developmental Toxicity, Oxidative Stress, and Apoptosis in Embryos and Zebrafish Larvae (Danio rerio)

Environ. Toxicol.31(10)

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality(Hatch)

LOEC

days

mg/L

0 mg/L / 0.10 mg/L / 0.40 mg/L / 0.70 mg/L / 1.00

16 ECOTOX

Wu,S., G. Ji, J. Liu, S. Zhang, Y. Gong, and L. Shi

TBBPA Induces Developmental Toxicity, Oxidative Stress, and Apoptosis in Embryos and Zebrafish Larvae (Danio rerio)

Environ. Toxicol.31(10)

2020/11/12

魚類

Danio rerio (Zebrafish)

Development//Abnormal

LOEC

142

hours

200

μg/L

0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Growth(Length)

LOEC

days

0.7

mg/L

0 mg/L / 0.10 mg/L / 0.40 mg/L / 0.70 mg/L / 1.00

16 ECOTOX

Wu,S., G. Ji, J. Liu, S. Zhang, Y. Gong, and L. Shi

TBBPA Induces Developmental Toxicity, Oxidative Stress, and Apoptosis in Embryos and Zebrafish Larvae (Danio rerio)

Environ. Toxicol.31(10)

2020/11/12

魚類

Danio rerio (Zebrafish)

Survival

LOEC

days

0.7

mg/L

0 mg/L / 0.10 mg/L / 0.40 mg/L / 0.70 mg/L / 1.00

16 ECOTOX

Wu,S., G. Ji, J. Liu, S. Zhang, Y. Gong, and L. Shi

TBBPA Induces Developmental Toxicity, Oxidative Stress, and Apoptosis in Embryos and Zebrafish Larvae (Danio rerio)

Environ. Toxicol.31(10)

2020/11/12

魚類

Danio rerio (Zebrafish)

Development//Teratogenic measurements

NOEC

days

0.1

mg/L

0 mg/L / 0.10 mg/L / 0.40 mg/L / 0.70 mg/L / 1.00

16 ECOTOX

Wu,S., G. Ji, J. Liu, S. Zhang, Y. Gong, and L. Shi

TBBPA Induces Developmental Toxicity, Oxidative Stress, and Apoptosis in Embryos and Zebrafish Larvae (Danio rerio)

Environ. Toxicol.31(10)

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality(Hatch)

NOEC

days

0.7

mg/L

0 mg/L / 0.10 mg/L / 0.40 mg/L / 0.70 mg/L / 1.00

16 ECOTOX

Wu,S., G. Ji, J. Liu, S. Zhang, Y. Gong, and L. Shi

TBBPA Induces Developmental Toxicity, Oxidative Stress, and Apoptosis in Embryos and Zebrafish Larvae (Danio rerio)

Environ. Toxicol.31(10)

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality(Hatch)

NOEC

142

hours

200

μg/L

0 ug/L / 200 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality

LC50

hours

1100

μg/L

0 ug/L / 82 ug/L / 160 ug/L / 330 ug/L / 650 ug/L

16 ECOTOX

Liu,H., Z. Ma, T. Zhang, N. Yu, G. Su, J.P. Giesy, and H. Yu

Pharmacokinetics and Effects of Tetrabromobisphenol A (TBBPA) to Early Life Stages of Zebrafish (Danio rerio)

Chemosphere190

2020/11/12

魚類

Danio rerio (Zebrafish)

Behavior//Activity, general

LOEC

112

hours

μM

0 uM / 5 uM

16 ECOTOX

Chen,J., R.L. Tanguay, Y. Xiao, D.E. Haggard, X. Ge, Y. Jia, Y. Zheng, Q. Dong, C. Huang, and K. Lin

TBBPA Exposure During a Sensitive Developmental Window Produces Neurobehavioral Changes in Larval Zebrafish

Environ. Pollut.216

2020/11/12

魚類

Danio rerio (Zebrafish)

Behavior//Swimming

LOEC

142

hours

200

μg/L

0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Survival

NOEC

142

hours

200

μg/L

0 ug/L / 200 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Behavior//Swimming

LOEC

142

hours

100

μg/L

0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Growth(Weight)

NOEC

142

hours

200

μg/L

0 ug/L / 200 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Development//Abnormal

NOEC

142

hours

200

μg/L

0 ug/L / 200 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Development//Deformation

NOEC

162

hours

1.25

ppm

0 ppm / 1.25 ppm / 2.5 ppm / 5.0 ppm / 10 ppm / 20

16 ECOTOX

Usenko,C.Y., E.L. Abel, A. Hopkins, G. Martinez, J. Tijerina, M. Kudela, N. Norris, L. Joudeh, and E.D. Bruce

Evaluation of Common Use Brominated Flame Retardant (BFR) Toxicity Using a Zebrafish Embryo Model

Toxics4(21)

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality

NOEC

162

hours

1.25

ppm

0 ppm / 1.25 ppm / 2.5 ppm / 5.0 ppm / 10 ppm / 20

16 ECOTOX

Usenko,C.Y., E.L. Abel, A. Hopkins, G. Martinez, J. Tijerina, M. Kudela, N. Norris, L. Joudeh, and E.D. Bruce

Evaluation of Common Use Brominated Flame Retardant (BFR) Toxicity Using a Zebrafish Embryo Model

Toxics4(21)

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality

LC50

days

0.0000036

16 ECOTOX

Kalasekar,S.M., E. Zacharia, N. Kessler, N.A. Ducharme, J.A. Gustafsson, I.A. Kakadiaris, and M. Bondesson

Identification of Environmental Chemicals that Induce Yolk Malabsorption in Zebrafish Using Automated Image Segmentation

Reprod. Toxicol.55

2020/11/12

魚類

Danio rerio (Zebrafish)

Development//Deformation

NOEC

162

hours

ppm

0 ppm / 1.25 ppm / 2.5 ppm / 5.0 ppm / 10 ppm / 20

16 ECOTOX

Usenko,C.Y., E.L. Abel, A. Hopkins, G. Martinez, J. Tijerina, M. Kudela, N. Norris, L. Joudeh, and E.D. Bruce

Evaluation of Common Use Brominated Flame Retardant (BFR) Toxicity Using a Zebrafish Embryo Model

Toxics4(21)

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality

NR-LETH

144

hours

1.5

mg/L

16 ECOTOX

Song,M., D. Liang, Y. Liang, M. Chen, F. Wang, H. Wang, and G. Jiang

Assessing Developmental Toxicity and Estrogenic Activity of Halogenated Bisphenol A on Zebrafish (Danio rerio)

Chemosphere112

2020/11/12

魚類

Danio rerio (Zebrafish)

Survival

NOEC

days

1.5

mg/L

0 mg/L / 0 mg/L / 0.5 mg/L / 1.0 mg/L / 1.5 mg/L

16 ECOTOX

Song,M., D. Liang, Y. Liang, M. Chen, F. Wang, H. Wang, and G. Jiang

Assessing Developmental Toxicity and Estrogenic Activity of Halogenated Bisphenol A on Zebrafish (Danio rerio)

Chemosphere112

2020/11/12

魚類

Danio rerio (Zebrafish)

Behavior//Activity, general

NOEC

hours

μM

0 uM / 5 uM

16 ECOTOX

Chen,J., R.L. Tanguay, Y. Xiao, D.E. Haggard, X. Ge, Y. Jia, Y. Zheng, Q. Dong, C. Huang, and K. Lin

TBBPA Exposure During a Sensitive Developmental Window Produces Neurobehavioral Changes in Larval Zebrafish

Environ. Pollut.216

2020/11/12

魚類

Danio rerio (Zebrafish)

Behavior//Swimming

NOEC

142

hours

200

μg/L

0 ug/L / 200 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Behavior//Swimming

NOEC

142

hours

200

μg/L

0 ug/L / 200 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Development//Abnormal

NOEC

142

hours

200

μg/L

0 ug/L / 200 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality(Hatch)

NOEC

142

hours

200

μg/L

0 ug/L / 200 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Survival

NOEC

142

hours

200

μg/L

0 ug/L / 200 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Physiology//Heart rate

NOEC

hours

100

μg/L

0 ug/L / 1.0 ug/L / 10 ug/L / 100 ug/L / 1000 ug/L

16 ECOTOX

Carlsson,G., and L. Norrgren

Comparison of Embryo Toxicity Using Two Classes of Aquatic Vertebrates

Environ. Toxicol. Pharmacol.37

2020/11/12

魚類

Danio rerio (Zebrafish)

Growth(Weight)

NOEC

142

hours

200

μg/L

0 ug/L / 200 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Behavior//Swimming

LOEC

142

hours

200

μg/L

0 ug/L / 200 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality

LOEC

144

hours

0.5

mg/L

16 ECOTOX

Song,M., D. Liang, Y. Liang, M. Chen, F. Wang, H. Wang, and G. Jiang

Assessing Developmental Toxicity and Estrogenic Activity of Halogenated Bisphenol A on Zebrafish (Danio rerio)

Chemosphere112

2020/11/12

魚類

Danio rerio (Zebrafish)

Physiology//Heart rate

LOEC

hours

1000

μg/L

0 ug/L / 1.0 ug/L / 10 ug/L / 100 ug/L / 1000 ug/L

16 ECOTOX

Carlsson,G., and L. Norrgren

Comparison of Embryo Toxicity Using Two Classes of Aquatic Vertebrates

Environ. Toxicol. Pharmacol.37

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality

LOEC

hours

1000

μg/L

0 ug/L / 1.0 ug/L / 10 ug/L / 100 ug/L / 1000 ug/L

16 ECOTOX

Carlsson,G., and L. Norrgren

Comparison of Embryo Toxicity Using Two Classes of Aquatic Vertebrates

Environ. Toxicol. Pharmacol.37

2020/11/12

魚類

Danio rerio (Zebrafish)

Physiology//Blood flow

LOEC

hours

1000

μg/L

0 ug/L / 1.0 ug/L / 10 ug/L / 100 ug/L / 1000 ug/L

16 ECOTOX

Carlsson,G., and L. Norrgren

Comparison of Embryo Toxicity Using Two Classes of Aquatic Vertebrates

Environ. Toxicol. Pharmacol.37

2020/11/12

魚類

Danio rerio (Zebrafish)

Development//Deformation

LOEC

162

hours

2.5

ppm

0 ppm / 1.25 ppm / 2.5 ppm / 5.0 ppm / 10 ppm / 20

16 ECOTOX

Usenko,C.Y., E.L. Abel, A. Hopkins, G. Martinez, J. Tijerina, M. Kudela, N. Norris, L. Joudeh, and E.D. Bruce

Evaluation of Common Use Brominated Flame Retardant (BFR) Toxicity Using a Zebrafish Embryo Model

Toxics4(21)

2020/11/12

魚類

Danio rerio (Zebrafish)

Behavior//Swimming

LOEC

142

hours

200

μg/L

0 ug/L / 200 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Behavior//Swimming

LOEC

142

hours

200

μg/L

0 ug/L / 200 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality

LOEC

162

hours

2.5

ppm

0 ppm / 1.25 ppm / 2.5 ppm / 5.0 ppm / 10 ppm / 20

16 ECOTOX

Usenko,C.Y., E.L. Abel, A. Hopkins, G. Martinez, J. Tijerina, M. Kudela, N. Norris, L. Joudeh, and E.D. Bruce

Evaluation of Common Use Brominated Flame Retardant (BFR) Toxicity Using a Zebrafish Embryo Model

Toxics4(21)

2020/11/12

魚類

Danio rerio (Zebrafish)

Behavior//Swimming

NOEC

142

hours

200

μg/L

0 ug/L / 200 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Behavior//Swimming

NOEC

hours

μM

0 uM / 5 uM

16 ECOTOX

Chen,J., R.L. Tanguay, Y. Xiao, D.E. Haggard, X. Ge, Y. Jia, Y. Zheng, Q. Dong, C. Huang, and K. Lin

TBBPA Exposure During a Sensitive Developmental Window Produces Neurobehavioral Changes in Larval Zebrafish

Environ. Pollut.216

2020/11/12

魚類

Danio rerio (Zebrafish)

Behavior//Distance moved, change in direct movement

NOEL

hours

3.8

μM

0 uM / 0 uM / 0 uM / 1.2 uM / 2.1 uM / 3.8 uM / 6.

16 ECOTOX

Jarema,K.A., D.L. Hunter, R.M. Shaffer, M. Behl, and S. Padilla

Acute and Developmental Behavioral Effects of Flame Retardants and Related Chemicals in Zebrafish

Neurotoxicol. Teratol.52

2020/11/12

魚類

Danio rerio (Zebrafish)

Behavior//Swimming

NOEC

142

hours

μg/L

0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality(Hatch)

NOEC

142

hours

400

μg/L

0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Development//Abnormal

NOEC

142

hours

100

μg/L

0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Behavior//Swimming

NOEC

112

hours

μM

0 uM / 5 uM

16 ECOTOX

Chen,J., R.L. Tanguay, Y. Xiao, D.E. Haggard, X. Ge, Y. Jia, Y. Zheng, Q. Dong, C. Huang, and K. Lin

TBBPA Exposure During a Sensitive Developmental Window Produces Neurobehavioral Changes in Larval Zebrafish

Environ. Pollut.216

2020/11/12

魚類

Danio rerio (Zebrafish)

Growth(Weight)

NOEC

142

hours

400

μg/L

0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Behavior//Swimming

NOEC

142

hours

μg/L

0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Survival

LOEC

142

hours

400

μg/L

0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

Physiology//Blood flow

NOEC

hours

100

μg/L

0 ug/L / 1.0 ug/L / 10 ug/L / 100 ug/L / 1000 ug/L

16 ECOTOX

Carlsson,G., and L. Norrgren

Comparison of Embryo Toxicity Using Two Classes of Aquatic Vertebrates

Environ. Toxicol. Pharmacol.37

2020/11/12

魚類

Danio rerio (Zebrafish)

Development//Slowed, Retarded, Delayed or Non-development

EC50

hours

1600

μg/L

0 ug/L / 82 ug/L / 160 ug/L / 330 ug/L / 650 ug/L

16 ECOTOX

Liu,H., Z. Ma, T. Zhang, N. Yu, G. Su, J.P. Giesy, and H. Yu

Pharmacokinetics and Effects of Tetrabromobisphenol A (TBBPA) to Early Life Stages of Zebrafish (Danio rerio)

Chemosphere190

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality

NOEC

hours

100

μg/L

0 ug/L / 1.0 ug/L / 10 ug/L / 100 ug/L / 1000 ug/L

16 ECOTOX

Carlsson,G., and L. Norrgren

Comparison of Embryo Toxicity Using Two Classes of Aquatic Vertebrates

Environ. Toxicol. Pharmacol.37

2020/11/12

魚類

Danio rerio (Zebrafish)

Morphology//Length

LOEC

hours

μM

0 uM / 5 uM

16 ECOTOX

Chen,J., R.L. Tanguay, Y. Xiao, D.E. Haggard, X. Ge, Y. Jia, Y. Zheng, Q. Dong, C. Huang, and K. Lin

TBBPA Exposure During a Sensitive Developmental Window Produces Neurobehavioral Changes in Larval Zebrafish

Environ. Pollut.216

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality

LC50

144

hours

1.24

mg/L

16 ECOTOX

Song,M., D. Liang, Y. Liang, M. Chen, F. Wang, H. Wang, and G. Jiang

Assessing Developmental Toxicity and Estrogenic Activity of Halogenated Bisphenol A on Zebrafish (Danio rerio)

Chemosphere112

2020/11/12

魚類

Danio rerio (Zebrafish)

Behavior//Swimming

NOEC

142

hours

100

μg/L

0 ug/L / 50 ug/L / 100 ug/L / 200 ug/L / 400 ug/L

16 ECOTOX

Zhu,B., G. Zhao, L. Yang, and B. Zhou

Tetrabromobisphenol A Caused Neurodevelopmental Toxicity via Disrupting Thyroid Hormones in Zebrafish Larvae

Chemosphere197

2020/11/12

魚類

Danio rerio (Zebrafish)

0 (control), 0.023, 0.047, 0.094, 0.188, 0.375, 0.750, 1.50, 3.00, 6.00 µM

12 ECHA Information on Registered Substances

Kuiper RV, van den Brandhof EJ, Leonards PEG, van der Ven LTM, Wester PW & Vos JG

Toxicity of Tetrabromobisphenol A (TBBPA) in zebrafish (Danio rerio) in a partial life-cycle test

Arch. Toxicol. 81

2007

魚類

Pimephales promelas (Fathead minnow)

mortality

NOEC

144

hours

0.26

mg/L

○

0.18, 0.27, 0.42, 0. 63, 1.0 mg/L

0.19, 0.26, 0.32, 0.45, 0.63 mg/L

12 ECHA Information on Registered Substances

study report

1988

2020/03/18

魚類

Pimephales promelas (Fathead minnow)

mortality

LC50

144

hours

0.49

mg/L

○

0.18, 0.27, 0.42, 0. 63, 1.0 mg/L

0.19, 0.26, 0.32, 0.45, 0.63 mg/L

12 ECHA Information on Registered Substances

study report

1988

2020/03/18

魚類

Danio rerio (Zebrafish)

Growth

NOEC

days

0.75

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Biochemical

NOEC

days

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Hu,J., Y. Liang, M. Chen, and X. Wang

Assessing the Toxicity of TBBPA and HBCD by Zebrafish Embryo Toxicity Assay and Biomarker Analysis

Environ. Toxicol.24(4): 334-342

2009

2016/03/25

魚類

Oncorhynchus mykiss (Rainbow trout)

Biochemical

その他others [mg/kg bdwt]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Christiansen,L.B., K.L. Pedersen, S.N. Pedersen, B. Korsgaard, and P. Bjerregaard

In Vivo Comparison of Xenoestrogens Using Rainbow Trout Vitellogenin Induction as a Screening System

Environ. Toxicol. Chem.19(7): 1867-1874

2000

2016/03/25

魚類

Danio rerio (Zebrafish)

Biochemical

NOEC

days

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Hu,J., Y. Liang, M. Chen, and X. Wang

Assessing the Toxicity of TBBPA and HBCD by Zebrafish Embryo Toxicity Assay and Biomarker Analysis

Environ. Toxicol.24(4): 334-342

2009

2016/03/25

魚類

Danio rerio (Zebrafish)

Biochemical

NOEC

days

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Hu,J., Y. Liang, M. Chen, and X. Wang

Assessing the Toxicity of TBBPA and HBCD by Zebrafish Embryo Toxicity Assay and Biomarker Analysis

Environ. Toxicol.24(4): 334-342

2009

2016/03/25

魚類

Danio rerio (Zebrafish)

Growth

NOEC

days

0.75

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Growth

NOEC

days

0.75

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

0.75～3

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Physiology

NOEC

days

0.75

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

NOEC

days

3950

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Biochemical

NOEC

days

250

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Riu,A., C.W. McCollum, C.L. Pinto, M. Grimaldi, A. Hillenweck, E. Perdu, D. Zalko, L. Bernard, V. Laudet, P. Balaguer, M

Halogenated Bisphenol-A Analogs Act as Obesogens in Zebrafish Larvae (Danio rerio)

Toxicol. Sci.139(1): 48-58

2014

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

NOEC

days

820

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

NOEC

days

550

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

NOEC

days

550

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

NOEC

days

820

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

NOEC

days

820

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

NOEC

days

820

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

NOEC

days

820

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

LOEL

days

3950

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chow,W.S., W.K.L. Chan, and K.M. Chan

Toxicity Assessment and Vitellogenin Expression in Zebrafish (Danio rerio) Embryos and Larvae Acutely Exposed to Bisphenol A, Endosulfan, Heptachlor, Methoxychlor and Tetrabromobisphenol A

J. Appl. Toxicol.33:670-678

2013

2016/03/25

魚類

Danio rerio (Zebrafish)

Biochemical

LOEL

days

550

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chow,W.S., W.K.L. Chan, and K.M. Chan

Toxicity Assessment and Vitellogenin Expression in Zebrafish (Danio rerio) Embryos and Larvae Acutely Exposed to Bisphenol A, Endosulfan, Heptachlor, Methoxychlor and Tetrabromobisphenol A

J. Appl. Toxicol.33:670-678

2013

2016/03/25

魚類

Danio rerio (Zebrafish)

Biochemical

LOEL

days

3950

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chow,W.S., W.K.L. Chan, and K.M. Chan

Toxicity Assessment and Vitellogenin Expression in Zebrafish (Danio rerio) Embryos and Larvae Acutely Exposed to Bisphenol A, Endosulfan, Heptachlor, Methoxychlor and Tetrabromobisphenol A

J. Appl. Toxicol.33:670-678

2013

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

LOEL

days

550

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chow,W.S., W.K.L. Chan, and K.M. Chan

Toxicity Assessment and Vitellogenin Expression in Zebrafish (Danio rerio) Embryos and Larvae Acutely Exposed to Bisphenol A, Endosulfan, Heptachlor, Methoxychlor and Tetrabromobisphenol A

J. Appl. Toxicol.33:670-678

2013

2016/03/25

魚類

Danio rerio (Zebrafish)

Physiology

NOEC

days

1.5

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Mortality

days

2640

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

days

400～1600

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Mortality

LC50

days

890

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Brooke,L.T.

Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI:110 p.

1991

2016/03/25

魚類

Danio rerio (Zebrafish)

Growth

2～1500

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Hu,J., Y. Liang, M. Chen, and X. Wang

Assessing the Toxicity of TBBPA and HBCD by Zebrafish Embryo Toxicity Assay and Biomarker Analysis

Environ. Toxicol.24(4): 334-342

2009

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

0.75

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M.

Microbial Transformations of Tetrabromobisphenol A and Its Metabolites, and Their Impact on Toxicity to the Developing Zebrafish (Danio rerio) Embryo

Ph.D.Thesis, Rutgers, The State University of New Jersey, New Brunswick, NJ:191 p.

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Biochemical

days

10～1000

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Riu,A., C.W. McCollum, C.L. Pinto, M. Grimaldi, A. Hillenweck, E. Perdu, D. Zalko, L. Bernard, V. Laudet, P. Balaguer, M

Halogenated Bisphenol-A Analogs Act as Obesogens in Zebrafish Larvae (Danio rerio)

Toxicol. Sci.139(1): 48-58

2014

2016/03/25

魚類

Danio rerio (Zebrafish)

Biochemical

days

0.75

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M.

Microbial Transformations of Tetrabromobisphenol A and Its Metabolites, and Their Impact on Toxicity to the Developing Zebrafish (Danio rerio) Embryo

Ph.D.Thesis, Rutgers, The State University of New Jersey, New Brunswick, NJ:191 p.

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Mortality

2～1500

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Hu,J., Y. Liang, M. Chen, and X. Wang

Assessing the Toxicity of TBBPA and HBCD by Zebrafish Embryo Toxicity Assay and Biomarker Analysis

Environ. Toxicol.24(4): 334-342

2009

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

days

400～1600

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Mortality

days

10～1000

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Riu,A., C.W. McCollum, C.L. Pinto, M. Grimaldi, A. Hillenweck, E. Perdu, D. Zalko, L. Bernard, V. Laudet, P. Balaguer, M

Halogenated Bisphenol-A Analogs Act as Obesogens in Zebrafish Larvae (Danio rerio)

Toxicol. Sci.139(1): 48-58

2014

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

NOEC

days

3950

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Mortality

days

820

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

NOEC

days

3950

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

NOEL

days

2640

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chow,W.S., W.K.L. Chan, and K.M. Chan

Toxicity Assessment and Vitellogenin Expression in Zebrafish (Danio rerio) Embryos and Larvae Acutely Exposed to Bisphenol A, Endosulfan, Heptachlor, Methoxychlor and Tetrabromobisphenol A

J. Appl. Toxicol.33:670-678

2013

2016/03/25

魚類

Danio rerio (Zebrafish)

Mortality

days

1500

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Hu,J., Y. Liang, M. Chen, and X. Wang

Assessing the Toxicity of TBBPA and HBCD by Zebrafish Embryo Toxicity Assay and Biomarker Analysis

Environ. Toxicol.24(4): 334-342

2009

2016/03/25

魚類

Danio rerio (Zebrafish)

Biochemical

NOEL

days

2640

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chow,W.S., W.K.L. Chan, and K.M. Chan

Toxicity Assessment and Vitellogenin Expression in Zebrafish (Danio rerio) Embryos and Larvae Acutely Exposed to Bisphenol A, Endosulfan, Heptachlor, Methoxychlor and Tetrabromobisphenol A

J. Appl. Toxicol.33:670-678

2013

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

NOEL

days

270

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chow,W.S., W.K.L. Chan, and K.M. Chan

Toxicity Assessment and Vitellogenin Expression in Zebrafish (Danio rerio) Embryos and Larvae Acutely Exposed to Bisphenol A, Endosulfan, Heptachlor, Methoxychlor and Tetrabromobisphenol A

J. Appl. Toxicol.33:670-678

2013

2016/03/25

魚類

Danio rerio (Zebrafish)

Biochemical

NOEL

days

270

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chow,W.S., W.K.L. Chan, and K.M. Chan

Toxicity Assessment and Vitellogenin Expression in Zebrafish (Danio rerio) Embryos and Larvae Acutely Exposed to Bisphenol A, Endosulfan, Heptachlor, Methoxychlor and Tetrabromobisphenol A

J. Appl. Toxicol.33:670-678

2013

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

NOEC

days

3950

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

NOEC

days

2640

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Physiology

LOEC

days

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

NOEC

days

2640

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Mortality

days

125～250

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Riu,A., C.W. McCollum, C.L. Pinto, M. Grimaldi, A. Hillenweck, E. Perdu, D. Zalko, L. Bernard, V. Laudet, P. Balaguer, M

Halogenated Bisphenol-A Analogs Act as Obesogens in Zebrafish Larvae (Danio rerio)

Toxicol. Sci.139(1): 48-58

2014

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

LOEC

days

0.75

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Reproduction

LOEC

days

400

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Mortality

LC50

days

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Brooke,L.T.

Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI:110 p.

1991

2016/03/25

魚類

Danio rerio (Zebrafish)

Mortality

LC50

days

>1.5～<1.8

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2): 199-204

1993

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Mortality

LC50

days

710

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Brooke,L.T.

Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI:110 p.

1991

2016/03/25

魚類

Danio rerio (Zebrafish)

Mortality

LC50

days

5270

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Mortality

EC50

days

1091

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chow,W.S., W.K.L. Chan, and K.M. Chan

Toxicity Assessment and Vitellogenin Expression in Zebrafish (Danio rerio) Embryos and Larvae Acutely Exposed to Bisphenol A, Endosulfan, Heptachlor, Methoxychlor and Tetrabromobisphenol A

J. Appl. Toxicol.33:670-678

2013

2016/03/25

魚類

Danio rerio (Zebrafish)

Physiology

LOEC

days

400

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Mortality

LOEC

days

400

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

LOEC

days

400

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Physiology

LOEC

days

1.5

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Growth

LOEC

days

400

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Mortality

LC50

days

1.6

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Mortality

LC50

days

5270

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chow,W.S., W.K.L. Chan, and K.M. Chan

Toxicity Assessment and Vitellogenin Expression in Zebrafish (Danio rerio) Embryos and Larvae Acutely Exposed to Bisphenol A, Endosulfan, Heptachlor, Methoxychlor and Tetrabromobisphenol A

J. Appl. Toxicol.33:670-678

2013

2016/03/25

魚類

Danio rerio (Zebrafish)

Mortality

LC50

days

1.5

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2): 199-204

1993

2016/03/25

魚類

Danio rerio (Zebrafish)

Mortality

LC50

days

>1.5～<1.8

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2): 199-204

1993

2016/03/25

魚類

Danio rerio (Zebrafish)

Mortality

LC50

days

>1.5～<1.8

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2): 199-204

1993

2016/03/25

魚類

Danio rerio (Zebrafish)

Mortality

EC50

days

1090

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Biochemical

LOEC

days

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Hu,J., Y. Liang, M. Chen, and X. Wang

Assessing the Toxicity of TBBPA and HBCD by Zebrafish Embryo Toxicity Assay and Biomarker Analysis

Environ. Toxicol.24(4): 334-342

2009

2016/03/25

魚類

Danio rerio (Zebrafish)

Biochemical

LOEC

days

0.75

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

LOEC

days

0.75

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

LOEC

days

0.75

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

LOEC

days

0.75

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

LOEC

days

0.75

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Biochemical

LOEC

days

0.75

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Biochemical

LOEC

days

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Hu,J., Y. Liang, M. Chen, and X. Wang

Assessing the Toxicity of TBBPA and HBCD by Zebrafish Embryo Toxicity Assay and Biomarker Analysis

Environ. Toxicol.24(4): 334-342

2009

2016/03/25

魚類

Danio rerio (Zebrafish)

Biochemical

LOEC

days

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Hu,J., Y. Liang, M. Chen, and X. Wang

Assessing the Toxicity of TBBPA and HBCD by Zebrafish Embryo Toxicity Assay and Biomarker Analysis

Environ. Toxicol.24(4): 334-342

2009

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

Mortality

LC50

days

1040

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Brooke,L.T.

Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI:110 p.

1991

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

LOEC

days

800

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

LOEC

days

530

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

LOEC

days

3950

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

LOEC

days

3950

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

LOEC

days

820

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

LOEC

days

820

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108:106-111

2012

2016/03/25

魚類

Danio rerio (Zebrafish)

Biochemical

LOEC

days

1000

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Thienpont,B., A. Tingaud-Sequeira, E. Prats, C. Barata, P.J. Babin, and D. Raldua

Zebrafish Eleutheroembryos Provide a Suitable Vertebrate Model for Screening Chemicals that Impair Thyroid Hormone Synthesis

Environ. Sci. Technol.45(17): 7525-7532

2011

2016/03/25

魚類

Danio rerio (Zebrafish)

Physiology

LOEC

days

400

μg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Danio rerio (Zebrafish)

Cellular Effects

LOEC

days

0.75

μM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3): 255-262

2010

2016/03/25

魚類

Pimephales promelas (Fathead minnow)

LC50

hours

0.54

mg/L

4 OECD SIDS (HPVC)

2020/01/17

魚類

Oryzias latipes (Japanese medaka)

Mortality

LC50

days

9190

μg/L

6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）

環境庁

平成11年度　生態影響試験実施事業報告

2000

2020/02/14

魚類

Brachydanio rerio (Zebrafish)

Mortality

LC50

hours

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.

Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.

Water Research, 27

1993

2019/12/24

魚類

Brachydanio rerio (Zebrafish)

Mortality

LC50

hours

3.1

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.

Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.

Water Research, 27

1993

2019/12/27

魚類

Brachydanio rerio (Zebrafish)

Mortality

LC50

hours

3.3

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.

Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.

Water Research, 27

1993

2019/12/27

魚類

Pimephales promelas (Fathead minnow)

LC50

hours

0.06

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Brooke L. T.

Results of freshwater exposures with the chemicals atrazine, biphenyl, butachlor, carbaryl, carbazole,　dibenzofuran, ３，３－dichlorobenzidine, dichlorvos….

Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

1991

2019/12/24

魚類

Pimephales promelas (Fathead minnow)

Mortality

LC50

hours

0.54

mg/L

0.19, 0.26, 0.32, 0.45 and 0.63mg/l plus control and acetone control

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Life Sciences

Acute toxicity of tetrabromobisphenol A to fathead minnow (Pimephales promelas) under flow-through conditions.

Report No 88-10-2834. Springborn Life Sciences, Inc. Wareham, Massachusetts.

1988

2019/12/27

魚類

Oncorhynchus mykiss (Rainbow trout)

Mortality

LC50

days

440

μg/L

6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）

若林

未発表

2020/02/14

魚類

Brachydanio rerio (Zebrafish)

Mortality

LC50

hours

3.4

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.

Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.

Water Research, 27

1993

2019/12/27

魚類

Oryzias latipes (Japanese medaka)

LC50

hours

>10

mg/L

○

対照区，助剤対照区，1.00, 1.80, 3.20, 5.60, 10.0mg/l

0.92, 1.85, 3.45, 5.22, 9.68mg/l

1 日本環境省　生態リスク初期評価

2020/01/08

魚類

Oryzias latipes (Japanese medaka)

LC50

hours

>10

mg/L

○

対照区，助剤対照区，1.00, 1.80, 3.20, 5.60, 10.0mg/l

0.92, 1.85, 3.45, 5.22, 9.68mg/l

1 日本環境省　生態リスク初期評価

2020/01/08

魚類

Oryzias latipes (Japanese medaka)

LC50

hours

>10

mg/L

○

対照区，助剤対照区，1.00, 1.80, 3.20, 5.60, 10.0mg/l

0.92, 1.85, 3.45, 5.22, 9.68mg/l

1 日本環境省　生態リスク初期評価

2020/01/08

魚類

Pimephales promelas (Fathead minnow)

LC50

hours

0.89

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Brooke L. T.

Results of freshwater exposures with the chemicals atrazine, biphenyl, butachlor, carbaryl, carbazole,　dibenzofuran, ３，３－dichlorobenzidine, dichlorvos….

Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

1991

2019/12/24

魚類

Pimephales promelas (Fathead minnow)

LC50

hours

0.71

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Brooke L. T.

Results of freshwater exposures with the chemicals atrazine, biphenyl, butachlor, carbaryl, carbazole,　dibenzofuran, ３，３－dichlorobenzidine, dichlorvos….

Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

1991

2019/12/24

魚類

Pimephales promelas (Fathead minnow)

LC50

hours

1.04

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Brooke L. T.

Results of freshwater exposures with the chemicals atrazine, biphenyl, butachlor, carbaryl, carbazole,　dibenzofuran, ３，３－dichlorobenzidine, dichlorvos….

Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

1991

2019/12/24

魚類

Pimephales promelas (Fathead minnow)

Mortality

LC50

120

hours

0.5

mg/L

0.19, 0.26, 0.32, 0.45 and 0.63mg/l plus control and acetone control

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Life Sciences

Acute toxicity of tetrabromobisphenol A to fathead minnow (Pimephales promelas) under flow-through conditions.

Report No 88-10-2834. Springborn Life Sciences, Inc. Wareham, Massachusetts.

1988

2019/12/27

魚類

Lepomis macrochirus (Bluegill)

Mortality

LC50

hours

0.51

mg/L

0.18, 0.32, 0.56, 1.00, 1.80 mg/l, control, acetone control

7 EU Risk Assessment Report (EUリスク評価書）

Union Carbide Corporation

The acute toxicity of FMBP 4A (tetrabromobisphenol A) to the bluegill sunfish, Lepomis macrochirus Rafinesque.

UCES Project Number 11506-03-50. Union Carbide Environmental Services, New York.

1978

2019/12/27

魚類

Pimephales promelas (Fathead minnow)

Mortality

LC50

hours

>0.63

mg/L

0.19, 0.26, 0.32, 0.45 and 0.63mg/l plus control and acetone control

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Life Sciences

Acute toxicity of tetrabromobisphenol A to fathead minnow (Pimephales promelas) under flow-through conditions.

Report No 88-10-2834. Springborn Life Sciences, Inc. Wareham, Massachusetts.

1988

2019/12/27

魚類

Oryzias latipes (Japanese medaka)

Mortality

LC50

hours

8.2

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

CITI

Biodegradation and bioaccumulation data of existing chemicals based on the CSCL.

Chemicals Inspection and Testing Institute, Tokyo, Japan. Summary available via the internet at http://www.citi.or.jp/e_index.htm.

1992

2019/12/24

魚類

Oncorhynchus mykiss (Rainbow trout)

Mortality

LC100

1.7

mg/L

1.1 and 1.7 mg/l plus control and solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Wildlife International

Tetrabromobisphenol A: A 96-hour flow-through acute toxicity test with the rainbow trout (Oncorhynchus mykiss).

Wildlife International Ltd., Project Number 439C-123.

2003

2019/12/24

魚類

Oncorhynchus mykiss (Rainbow trout)

Mortality

LC45

1.1

mg/L

1.1 and 1.7 mg/l plus control and solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Wildlife International

Tetrabromobisphenol A: A 96-hour flow-through acute toxicity test with the rainbow trout (Oncorhynchus mykiss).

Wildlife International Ltd., Project Number 439C-123.

2003

2019/12/24

魚類

Oncorhynchus mykiss (Rainbow trout)

Mortality

LC50

hours

0.4

mg/L

0.1, 0.18, 0.32, 0.56, and 1.00 mg/l plus control and acetone control

7 EU Risk Assessment Report (EUリスク評価書）

Union Carbide Corporation

The acute toxicity of FMBP 4A (tetrabromobisphenol A) to the rainbow trout, Salmo gairdneri Richardson.

UCES Project Number 11506-03-51. Union Carbide Environmental Services, New York.

1978

2019/12/24

魚類

Oncorhynchus mykiss (Rainbow trout)

Mortality

LC50

hours

0.67

mg/L

0.1, 0.18, 0.32, 0.56, and 1.00 mg/l plus control and acetone control

7 EU Risk Assessment Report (EUリスク評価書）

Union Carbide Corporation

The acute toxicity of FMBP 4A (tetrabromobisphenol A) to the rainbow trout, Salmo gairdneri Richardson.

UCES Project Number 11506-03-51. Union Carbide Environmental Services, New York.

1978

2019/12/24

魚類

Oryzias latipes (Japanese medaka)

Mortality

LC0

hours

3.2

mg/L

0, 1.00, 1.80, 3.20, 5.60, 10.0mg/l

設定値の99～116％（0h)、81～101％（24h)

18 既存化学物質安全性(ハザード)評価シート

環境省

既存化学物質審査シート（三監No.10）

2020/01/08

魚類

Oryzias latipes (Japanese medaka)

Mortality

LC50

hours

9.19

mg/L

0, 1.00, 1.80, 3.20, 5.60, 10.0mg/l

設定値の99～116％（0h)、81～101％（24h)

18 既存化学物質安全性(ハザード)評価シート

環境省

既存化学物質審査シート（三監No.10）

2020/01/08

魚類

Lepomis macrochirus (Bluegill)

Mortality

LC50

hours

0.51

mg/L

0.18, 0.32, 0.56, 1.00, 1.80 mg/l, control, acetone control

7 EU Risk Assessment Report (EUリスク評価書）

Union Carbide Corporation

The acute toxicity of FMBP 4A (tetrabromobisphenol A) to the bluegill sunfish, Lepomis macrochirus Rafinesque.

UCES Project Number 11506-03-50. Union Carbide Environmental Services, New York.

1978

2019/12/27

魚類

Pimephales promelas (Fathead minnow)

Mortality

LC50

144

hours

0.49

mg/L

0.19, 0.26, 0.32, 0.45 and 0.63mg/l plus control and acetone control

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Life Sciences

Acute toxicity of tetrabromobisphenol A to fathead minnow (Pimephales promelas) under flow-through conditions.

Report No 88-10-2834. Springborn Life Sciences, Inc. Wareham, Massachusetts.

1988

2019/12/27

魚類

Pimephales promelas (Fathead minnow)

LC50

hours

540

μg/L

○

190, 260, 320, 450, 630µg/l

14 BUA Report

Great Lakes Chemical Corporation

Acute toxicity of tetrabromobisphenol A to fathead minnow (Pimephales promelas) under flow-through conditions. Springborn Laboratories, SLS Report: 88-10-2834

1988

2020/01/21

魚類

Lepomis macrochirus (Bluegill)

Mortality

NOEC

hours

0.1

mg/L

14 BUA Report

Velsicol Chemical Corporation

The acute toxicity of tetrabromobisphenol A to the bluegill sunfish, Lepomis macrochirus Rafinesque. UCES Project: 11506-03-50

1978

2020/01/21

魚類

Oncorhynchus mykiss (Rainbow trout)

LC50

hours

400

μg/L

14 BUA Report

Velsicol Chemical Corporation

The acute toxicity of tetrabromobisphenol A to the rainbow trout, Salmo gairdneri Richardson. UCES Project: 11506-03-51

1978

2020/01/21

魚類

Lepomis macrochirus (Bluegill)

LC50

hours

510

μg/L

14 BUA Report

Velsicol Chemical Corporation

The acute toxicity of tetrabromobisphenol A to the bluegill sunfish, Lepomis macrochirus Rafinesque. UCES Project: 11506-03-50

1978

2020/01/21

魚類

Pimephales promelas (Fathead minnow)

Mortality

NOEC

hours

0.26

mg/L

○

190, 260, 320, 450, 630µg/l

14 BUA Report

Great Lakes Chemical Corporation

Acute toxicity of tetrabromobisphenol A to fathead minnow (Pimephales promelas) under flow-through conditions. Springborn Laboratories, SLS Report: 88-10-2834

1988

2020/01/21

魚類

Pimephales promelas (Fathead minnow)

LC50

144

hours

490

μg/L

○

190, 260, 320, 450, 630µg/l

14 BUA Report

Great Lakes Chemical Corporation

Acute toxicity of tetrabromobisphenol A to fathead minnow (Pimephales promelas) under flow-through conditions. Springborn Laboratories, SLS Report: 88-10-2834

1988

2020/01/21

魚類

Mortality

LC50

hours

0.00195

mmol/L

17 Aquatic OASIS (OECD QSAR Toolbox)

Russom, C.L., Bradbury, S.P., Broderius, S.J., Drummond, R.A. and Hammermeister, D.E.

PREDICTING MODES OF TOXIC ACTION FROM CHEMICAL STRUCTURE: ACUTE TOXICITY IN THE FATHEAD MINNOW (PIMEPHALES PROMELAS)

Environmental Toxicology and Chemistry, Vol. 16, No. 5, pp. 948–967.

1997

魚類

Danio rerio (Zebrafish)

LC50

hours

3000

μg/L

14 BUA Report

Lee SK, Freitag, D, Steinberg C, Kettrup A, Kim YH

Effects of dissolved humic material on acute toxicity of some organic chemicals to aquatic organisms.

Wat Res 27(2)

1993

2020/01/21

魚類

Mortality

LC50

hours

0.0151

mmol/L

17 Aquatic OASIS (OECD QSAR Toolbox)

Biodegradation and Bioaccumulation Data of Existing Chemicals Based on the CSCL Japan

Chemicals Investigation and Testing Institute. 1992. Biodegradation and Bioaccumulation Data of Existing Chemicals Based on the CSCL Japan, ISBN 4-98074-101-1. Japan Chemical Industry Ecology-Toxicology&Information Center;

1992

魚類

Oncorhynchus mykiss (Rainbow trout)

Mortality

NOEC

hours

0.18

mg/L

14 BUA Report

Velsicol Chemical Corporation

The acute toxicity of tetrabromobisphenol A to the rainbow trout, Salmo gairdneri Richardson. UCES Project: 11506-03-51

1978

2020/01/21

魚類

Oryzias latipes (Japanese medaka)

LC50

hours

8200

μg/L

14 BUA Report

MITI

Data of Existing chemicals based on the CSCL Japan. Ministry of International Trade & Industry Japan, 1992

1992

2020/01/21

魚類

Oryzias latipes (Japanese medaka)

LC50

hours

9.19

mg/L

○

対照区，助剤対照区，1.00, 1.80, 3.20, 5.60, 10.0mg/l

0.92, 1.85, 3.45, 5.22, 9.68mg/l

1 日本環境省　生態リスク初期評価

2020/01/08

魚類

Danio rerio (Zebrafish)

MortalityMortality

EC50 EC50

hours

1.091

mg/L [Active ingredient]

0 mg/L / >0-<4 mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chow,W.S., W.K.L. Chan, and K.M. Chan

Toxicity Assessment and Vitellogenin Expression in Zebrafish (Danio rerio) Embryos and Larvae Acutely Exposed to Bisphenol A, Endosulfan, Heptachlor, Methoxychlor and Tetrabromobisphenol A

J. Appl. Toxicol.33

2013

魚類

Danio rerio (Zebrafish)

MortalityMortality

LC50 LC50

hours

>3～<3.6

mg/L [Active ingredient]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2)

1993

魚類

Danio rerio (Zebrafish)

MortalityHatch

EC50 EC50

hours

1.09

mg/L [Active ingredient]

0 mg/L / >0-<5 mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108

2012

魚類

Pimephales promelas (Fathead minnow)

MortalityMortality

LC50 LC50

hours

1040

μg/L [Active ingredient]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Brooke,L.T.

Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI

1991

魚類

Danio rerio (Zebrafish)

MortalityMortality

LC50 LC50

hours

>3～<3.6

mg/L [Active ingredient]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2)

1993

魚類

Danio rerio (Zebrafish)

MortalityMortality

LC50 LC50

hours

mg/L [Active ingredient]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2)

1993

魚類

Danio rerio (Zebrafish)

MortalityMortality

LC50 LC50

hours

1.6

μM [Active ingredient]

0 uM / 0.5 uM / 0.75 uM / 1 uM / 1.5 uM / 3 uM

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R. Cooper, and L.A. White

Aquat. Toxicol.100(3)

2010

魚類

Danio rerio (Zebrafish)

MortalityMortality

LC50 LC50

hours

5.27

mg/L [Active ingredient]

0 mg/L / 4-10 mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chan,W.K., and K.M. Chan

Disruption of the Hypothalamic-Pituitary-Thyroid Axis in Zebrafish Embryo-Larvae Following Waterborne Exposure to BDE-47, TBBPA and BPA

Aquat. Toxicol.108

2012

魚類

Danio rerio (Zebrafish)

MortalityMortality

LC50 LC50

hours

>3～<3.6

mg/L [Active ingredient]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2)

1993

魚類

Pimephales promelas (Fathead minnow)

MortalityMortality

LC50 LC50

hours

710

μg/L [Active ingredient]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Brooke,L.T.

Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI

1991

魚類

Oncorhynchus mykiss (Rainbow trout)

MortalityMortality

NOEC NOEC

hours

<1.1

mg/L [Active ingredient]

<0.250 AI mg/L / <0.250 AI mg/L / 1.1 (0.902-1.15) AI mg/L / 1.7 (1.35-1.91) AI mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Wildlife International Ltd.

Tetrabromobisphenol A: A 48-Hour Flow-Through Acute Toxicity Test with the Cladoceran (Daphnia magna)

Wildlife International, LTD. Project Number

2003

魚類

Danio rerio (Zebrafish)

MortalityMortality

LC50 LC50

hours

5.27

mg/L [Active ingredient]

0 mg/L / >=4-<=10 mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Chow,W.S., W.K.L. Chan, and K.M. Chan

Toxicity Assessment and Vitellogenin Expression in Zebrafish (Danio rerio) Embryos and Larvae Acutely Exposed to Bisphenol A, Endosulfan, Heptachlor, Methoxychlor and Tetrabromobisphenol A

J. Appl. Toxicol.33

2013

魚類

Pimephales promelas (Fathead minnow)

MortalityMortality

LC50 LC50

hours

μg/L [Active ingredient]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Brooke,L.T.

Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI

1991

魚類

Pimephales promelas (Fathead minnow)

MortalityMortality

LC50 LC50

hours

890

μg/L [Active ingredient]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Brooke,L.T.

Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI

1991

魚類

Oncorhynchus mykiss (Rainbow trout)

MortalityMortality

LC50 LC50

hours

1.1

mg/L [Active ingredient]

<0.250 AI mg/L / <0.250 AI mg/L / 1.1 (0.902-1.15) AI mg/L / 1.7 (1.35-1.91) AI mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Wildlife International Ltd.

Tetrabromobisphenol A: A 48-Hour Flow-Through Acute Toxicity Test with the Cladoceran (Daphnia magna)

Wildlife International, LTD. Project Number

2003

魚類

Oncorhynchus mykiss (Rainbow trout)

MortalityMortality

LC50 LC50

hours

>1.7

mg/L [Active ingredient]

<0.250 AI mg/L / <0.250 AI mg/L / 1.1 (0.902-1.15) AI mg/L / 1.7 (1.35-1.91) AI mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Wildlife International Ltd.

Tetrabromobisphenol A: A 48-Hour Flow-Through Acute Toxicity Test with the Cladoceran (Daphnia magna)

Wildlife International, LTD. Project Number

2003

魚類

Oncorhynchus mykiss (Rainbow trout)

MortalityMortality

LC50 LC50

hours

1.4

mg/L [Active ingredient]

<0.250 AI mg/L / <0.250 AI mg/L / 1.1 (0.902-1.15) AI mg/L / 1.7 (1.35-1.91) AI mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Wildlife International Ltd.

Tetrabromobisphenol A: A 48-Hour Flow-Through Acute Toxicity Test with the Cladoceran (Daphnia magna)

Wildlife International, LTD. Project Number

2003

魚類

Oncorhynchus mykiss (Rainbow trout)

MortalityMortality

LC50 LC50

hours

1.2

mg/L [Active ingredient]

<0.250 AI mg/L / <0.250 AI mg/L / 1.1 (0.902-1.15) AI mg/L / 1.7 (1.35-1.91) AI mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Wildlife International Ltd.

Tetrabromobisphenol A: A 48-Hour Flow-Through Acute Toxicity Test with the Cladoceran (Daphnia magna)

Wildlife International, LTD. Project Number

2003

魚類

Oncorhynchus mykiss (Rainbow trout)

MortalityMortality

LOEC LOEC

hours

1.1

mg/L [Active ingredient]

<0.250 AI mg/L / <0.250 AI mg/L / 1.1 (0.902-1.15) AI mg/L / 1.7 (1.35-1.91) AI mg/L

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Wildlife International Ltd.

Tetrabromobisphenol A: A 48-Hour Flow-Through Acute Toxicity Test with the Cladoceran (Daphnia magna)

Wildlife International, LTD. Project Number

2003

魚類

Danio rerio (Zebrafish)

MortalityMortality

LC50 LC50

hours

1.3

ppm [Formulation]

16 US EPA AQUIRE (AQUatic toxicity Information REtrieval)

Godfrey,A., A. Abdel-Moneim, and M.S. Sepulveda

Acute Mixture Toxicity of Halogenated Chemicals and Their Next Generation Counterparts on Zebrafish Embryos

Chemosphere181

2017

魚類

Cyprinus carpio (Carp)

mortality

LC50

hours

0.71

mg/L

○

0.42, 0.65, 1.0 mg TBBA/L

12 ECHA Information on Registered Substances

study report

1998

魚類

Cyprinus carpio (Carp)

mortality

LC50

hours

0.8

mg/L

○

0.42, 0.65, 1.0 mg TBBA/L

12 ECHA Information on Registered Substances

study report

1998

魚類

Pimephales promelas (Fathead minnow)

mortality

LC50

hours

0.54

mg/L

○

0.18, 0.27, 0.42, 0. 63, 1.0 mg/L

0.19, 0.26, 0.32, 0.45, 0.63 mg/L

12 ECHA Information on Registered Substances

study report

1988

魚類

Oncorhynchus mykiss (Rainbow trout)

mortality

LC50

hours

1.1

mg/L

○

1.2, 1.8 mg/L TBBPA

1.1, 1.7 mg/L TBBPA

12 ECHA Information on Registered Substances

study report

2003

魚類

Oncorhynchus mykiss (Rainbow trout)

mortality

NOEC

hours

<1.1

mg/L

○

1.2, 1.8 mg/L TBBPA

1.1, 1.7 mg/L TBBPA

12 ECHA Information on Registered Substances

study report

2003

魚類

Lepomis macrochirus (Bluegill)

mortality

LC50

hours

0.72

mg/L

0.18, 0.32, 0.56, 1.00, 1.8 mg TBBPA/L

12 ECHA Information on Registered Substances

study report

1978

魚類

Lepomis macrochirus (Bluegill)

mortality

LC50

hours

0.51

mg/L

0.18, 0.32, 0.56, 1.00, 1.8 mg TBBPA/L

12 ECHA Information on Registered Substances

study report

1978

魚類

Lepomis macrochirus (Bluegill)

mortality

LC50

hours

0.51

mg/L

0.18, 0.32, 0.56, 1.00, 1.8 mg TBBPA/L

12 ECHA Information on Registered Substances

study report

1978

魚類

Oncorhynchus mykiss (Rainbow trout)

mortality

LC50

hours

0.4

mg/L

0.1, 0.32, 0.56, 1.00 mg TBBPA/L

12 ECHA Information on Registered Substances

study report

1978

魚類

Pimephales promelas

mortality

NOEC

days

0.16

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

魚類

Pimephales promelas

mortality

LOEC

days

0.31

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

魚類

Lepomis macrochirus

mortality

LC50

hours

0.51

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

魚類

Lepomis macrochirus

mortality

LC50

hours

0.51

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

魚類

Lepomis macrochirus

mortality

LC50

hours

0.72

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

hours

0.8

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

魚類

Pimephales promelas

mortality

LC50

144

hours

0.49

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

魚類

Pimephales promelas

mortality

NOEC

144

hours

0.26

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

魚類

Pimephales promelas

mortality

LC50

hours

0.54

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

魚類

Cyprinus carpio (Carp)

mortality

LC50

hours

0.71

mg/L

12 ECHA Information on Registered Substances

study report

2021/03/02

魚類

Oryzias latipes (Japanese medaka)

LC50

hours

9.2

mg/L

1 日本環境省　生態リスク初期評価

環境省

（Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版）

2016/11/09

魚類

Lepomis macrochirus (Bluegill)

mortality

LC50

hours

0.51

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Union Carbide Corporation

The acute toxicity of FMBP 4A (tetrabromobisphenol A) to the bluegill sunfish, Lepomis macrochirus Rafinesque.

UCES Project Number 11506-03-50. Union Carbide Environmental Services, New York.

1978

2016/03/04

魚類

Pimephales promelas (Fathead minnow)

LC50

hours

1.04

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Brooke L. T.

Results of freshwater exposures with the chemicals atrazine, biphenyl, butachlor, carbaryl, carbazole, dibenzofuran, 3,3-dichlorobenzidine, dichlorvos….

Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

1991

2016/03/04

魚類

Lepomis macrochirus (Bluegill)

hours

0.1

mg/L

10 EHC (Environmental Health Criteria)

Calmbacher CW

The acute toxicity of FMBP4A (tetrabromobisphenol A) to the bluegill sunfish, Lepomis macrochirus Rafinesque.

Tarrytown, New York, Union Carbide Corporation, Environmental Services (Report to Velsicol Chemical Corporation, Chicago, submitted to WHO by the Brominated Flame Retardant Industry Panel).

1987

2016/03/04

魚類

Pimephales promelas (Fathead minnow)

mortality

LC50

144

hours

0.49

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Life Sciences

Acute toxicity of tetrabromobisphenol A to fathead minnow (Pimephales promelas) under flow-through conditions.

No 88-10-2834. Springborn Life Sciences, Inc. Wareham, Massachusetts.

1988

2016/03/04

魚類

Lepomis macrochirus (Bluegill)

mortality

LC50

hours

0.51

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Union Carbide Corporation

The acute toxicity of FMBP 4A (tetrabromobisphenol A) to the bluegill sunfish, Lepomis macrochirus Rafinesque.

UCES Project Number 11506-03-50. Union Carbide Environmental Services, New York.

1978

2016/03/04

魚類

Oryzias latipes (Japanese medaka)

死亡

LC50

days

2.1

mg/L

11 Japan チャレンジプログラム

2,2-ビス［4-ヒドロキシ-3，5-ジブロモフェニル］プロパンのヒメダカ（Oryzias latipes)に対する延長毒性試験-21日間

EFP95005

2016/03/08

魚類

Brachydanio rerio (Zebrafish)

mortality

LC50

hours

3.1

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.

Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.

Water Research, 27

1993

2016/03/04

魚類

Lepomis macrochirus (Bluegill)

mortality

LC50

hours

0.51

mg/L

10 EHC (Environmental Health Criteria)

Calmbacher CW

The acute toxicity of FMBP4A (tetrabromobisphenol A) to the bluegill sunfish, Lepomis macrochirus Rafinesque.

Tarrytown, New York, Union Carbide Corporation, Environmental Services (Report to Velsicol Chemical Corporation, Chicago, submitted to WHO by the Brominated Flame Retardant Industry Panel).

1987

2016/03/04

魚類

Oncorhynchus mykiss (Rainbow trout)

hours

0.18

mg/L

10 EHC (Environmental Health Criteria)

Calmbacher CW

The acute toxicity of FMBP4A (tetrabromobisphenol A) to the bluegill sunfish, Lepomis macrochirus Rafinesque.

Tarrytown, New York, Union Carbide Corporation, Environmental Services (Report to Velsicol Chemical Corporation, Chicago, submitted to WHO by the Brominated Flame Retardant Industry Panel).

1987

2016/03/04

魚類

Oryzias latipes (Japanese medaka)

Mortality

LC50

days

9190

μg/L

6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）

環境庁

平成 11 年度　生態影響試験実施事業報告

2000

2016/03/05

魚類

Oncorhynchus mykiss (Rainbow trout)

mortality

LC50

hours

0.67

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Union Carbide Corporation

The acute toxicity of FMBP 4A (tetrabromobisphenol A) to the rainbow trout, Salmo gairdneri Richardson.

UCES Project Number 11506-03-51. Union Carbide Environmental Services, New York.

1978

2016/03/04

魚類

Brachydanio rerio (Zebrafish)

mortality

LC50

hours

3.4

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.

Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.

Water Research, 27

1993

2016/03/04

魚類

Oryzias latipes (Japanese medaka)

死亡

LC50

days

1.8

mg/L

11 Japan チャレンジプログラム

2,2-ビス［4-ヒドロキシ-3，5-ジブロモフェニル］プロパンのヒメダカ（Oryzias latipes)に対する延長毒性試験-21日間

EFP95005

2016/03/08

魚類

Oncorhynchus mykiss (Rainbow trout)

Mortality

LC50

days

440

μg/L

6 日本環境省　化学物質の環境リスク評価（生態リスク初期評価）

若林

未発表

2016/03/05

魚類

Oncorhynchus mykiss (Rainbow trout)

mortality

LC100

hours

1.7

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Wildlife International

Tetrabromobisphenol A: A 96-hour flow-through acute toxicity test with the rainbow trout (Oncorhynchus mykiss).

Wildlife International Ltd., Project Number 439C-123.

2003

2016/03/04

魚類

Brachydanio rerio (Zebrafish)

mortality

LC50

hours

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.

Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.

Water Research, 27

1993

2016/03/04

魚類

Oryzias latipes (Japanese medaka)

死亡

最小致死濃度

days

0.78

mg/L

11 Japan チャレンジプログラム

2,2-ビス［4-ヒドロキシ-3，5-ジブロモフェニル］プロパンのヒメダカ（Oryzias latipes)に対する延長毒性試験-21日間

EFP95005

2016/03/08

魚類

Brachydanio rerio (Zebrafish)

mortality

LC50

hours

3.3

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Lee S. K., Freitag D., Steinberg C., Kettrup A. and Kim Y. H.

Effects of dissolved humic materials on acute toxicity of some organic chemicals to aquatic organisms.

Water Research, 27

1993

2016/03/04

魚類

Oryzias latipes (Japanese medaka)

mortality

LC50

hours

8.2

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

CITI

Biodegradation and bioaccumulation data of existing chemicals based on the CSCL. Chemicals Inspection and Testing Institute, Tokyo, Japan.

1992

2016/03/04

魚類

Oryzias latipes (Japanese medaka)

死亡

LC50

days

1.4

mg/L

11 Japan チャレンジプログラム

2,2-ビス［4-ヒドロキシ-3，5-ジブロモフェニル］プロパンのヒメダカ（Oryzias latipes)に対する延長毒性試験-21日間

EFP95005

2016/03/08

魚類

Pimephales promelas (Fathead minnow)

mortality

LC50

hours

>0.63

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Life Sciences

Acute toxicity of tetrabromobisphenol A to fathead minnow (Pimephales promelas) under flow-through conditions.

No 88-10-2834. Springborn Life Sciences, Inc. Wareham, Massachusetts.

1988

2016/03/04

魚類

Oryzias latipes (Japanese medaka)

死亡

LC50

hours

9.19

mg/L

11 Japan チャレンジプログラム

4，4'-イソプロピリデンビス（2，6-ジブロモフェノール）のヒメダカ（Oryzias latipes)に対する急性毒性試験

9B500G

2016/03/08

魚類

Oncorhynchus mykiss (Rainbow trout)

mortality

LC50

hours

0.4

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Union Carbide Corporation

The acute toxicity of FMBP 4A (tetrabromobisphenol A) to the rainbow trout, Salmo gairdneri Richardson.

UCES Project Number 11506-03-51. Union Carbide Environmental Services, New York.

1978

2016/03/04

魚類

Oryzias latipes (Japanese medaka)

死亡

LC50

hours

2.4

mg/L

11 Japan チャレンジプログラム

2,2-ビス［4-ヒドロキシ-3，5-ジブロモフェニル］プロパンのヒメダカ（Oryzias latipes)に対する急性毒性試験

EFA95005

2016/03/08

魚類

Oncorhynchus mykiss (Rainbow trout)

mortality

LC50

hours

0.4

mg/L

10 EHC (Environmental Health Criteria)

Calmbacher CW

The acute toxicity of FMBP4A (tetrabromobisphenol A) to the bluegill sunfish, Lepomis macrochirus Rafinesque.

Tarrytown, New York, Union Carbide Corporation, Environmental Services (Report to Velsicol Chemical Corporation, Chicago, submitted to WHO by the Brominated Flame Retardant Industry Panel).

1987

2016/03/04

魚類

Pimephales promelas (Fathead minnow)

LC50

hours

0.71

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Brooke L. T.

Results of freshwater exposures with the chemicals atrazine, biphenyl, butachlor, carbaryl, carbazole, dibenzofuran, 3,3-dichlorobenzidine, dichlorvos….

Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

1991

2016/03/04

魚類

Pimephales promelas (Fathead minnow)

LC50

hours

0.89

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Brooke L. T.

Results of freshwater exposures with the chemicals atrazine, biphenyl, butachlor, carbaryl, carbazole, dibenzofuran, 3,3-dichlorobenzidine, dichlorvos….

Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

1991

2016/03/04

魚類

Pimephales promelas (Fathead minnow)

LC50

hours

0.06

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Brooke L. T.

Results of freshwater exposures with the chemicals atrazine, biphenyl, butachlor, carbaryl, carbazole, dibenzofuran, 3,3-dichlorobenzidine, dichlorvos….

Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

1991

2016/03/04

魚類

Pimephales promelas (Fathead minnow)

mortality

LC50

hours

0.54

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Life Sciences

Acute toxicity of tetrabromobisphenol A to fathead minnow (Pimephales promelas) under flow-through conditions.

No 88-10-2834. Springborn Life Sciences, Inc. Wareham, Massachusetts.

1988

2016/03/04

魚類

Pimephales promelas (Fathead minnow)

mortality

LC50

hours

0.54

mg/L

10 EHC (Environmental Health Criteria)

Calmbacher CW

The acute toxicity of FMBP4A (tetrabromobisphenol A) to the bluegill sunfish, Lepomis macrochirus Rafinesque.

Tarrytown, New York, Union Carbide Corporation, Environmental Services (Report to Velsicol Chemical Corporation, Chicago, submitted to WHO by the Brominated Flame Retardant Industry Panel).

1987

2016/03/04

魚類

Pimephales promelas (Fathead minnow)

mortality

LC50

120

hours

0.5

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Life Sciences

Acute toxicity of tetrabromobisphenol A to fathead minnow (Pimephales promelas) under flow-through conditions.

No 88-10-2834. Springborn Life Sciences, Inc. Wareham, Massachusetts.

1988

2016/03/04

魚類

Pimephales promelas (Fathead minnow)

LC50

hours

0.54

mg/L

4 OECD SIDS (HPVC)

2016/02/19

魚類

Danio rerio (Zebrafish)

Physiology//Blood flow

NOEC

114

hours

61.12

μM

0 uM / 0.0061 uM / 0.0611 uM / 0.6112 uM / 6.112 u

16 ECOTOX

Truong,L., D.M. Reif, L. St Mary, M.C. Geier, H.D. Truong, and R.L. Tanguay

Multidimensional In Vivo Hazard Assessment Using Zebrafish

Toxicol. Sci.137(1)

2020/11/12

魚類

Danio rerio (Zebrafish)

Growth//Stunting

NOEC

114

hours

61.12

μM

0 uM / 0.0061 uM / 0.0611 uM / 0.6112 uM / 6.112 u

16 ECOTOX

Truong,L., D.M. Reif, L. St Mary, M.C. Geier, H.D. Truong, and R.L. Tanguay

Multidimensional In Vivo Hazard Assessment Using Zebrafish

Toxicol. Sci.137(1)

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality

NOEC

114

hours

0.6112

μM

0 uM / 0.0061 uM / 0.0611 uM / 0.6112 uM / 6.112 u

16 ECOTOX

Truong,L., D.M. Reif, L. St Mary, M.C. Geier, H.D. Truong, and R.L. Tanguay

Multidimensional In Vivo Hazard Assessment Using Zebrafish

Toxicol. Sci.137(1)

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality

LC50

hours

>3～3.6

mg/L

16 ECOTOX

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2)

2020/11/12

魚類

Danio rerio (Zebrafish)

Morphology//Abnormal

NOEC

114

hours

61.12

μM

0 uM / 0.0061 uM / 0.0611 uM / 0.6112 uM / 6.112 u

16 ECOTOX

Truong,L., D.M. Reif, L. St Mary, M.C. Geier, H.D. Truong, and R.L. Tanguay

Multidimensional In Vivo Hazard Assessment Using Zebrafish

Toxicol. Sci.137(1)

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality

LC50

hours

>3～3.6

mg/L

16 ECOTOX

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2)

2020/11/12

魚類

Pimephales promelas

Mortality

LC50

hours

750

mg/L

0 mg/L / 250 mg/L / 750 mg/L

16 ECOTOX

Cytec Industries

Tetrabromobisphenol A: Report of Analytical Results - CAM Bioassay Screen in Pimephales promelas and Fathead Minnows with Cover Letter Dated 122292

EPA/OTS 86-930000091

2020/11/12

魚類

Pimephales promelas

Mortality

LC50

hours

0.57

AI mg/L

<0.032 AI mg/L / <0.032 AI mg/L / 0.19 (0.17-0.21)

16 ECOTOX

Great Lakes Chemical Corp.

Acute Toxicity of Tetrabromobisphenol A to Fathead Minnow (Pimephales promelas) Under Flow-Through Conditions with Attachments and Cover Letter Dated 111788

EPA/OTS 40-8898095

2020/11/12

魚類

Pimephales promelas

Mortality

LC50

hours

0.63

AI mg/L

<0.032 AI mg/L / <0.032 AI mg/L / 0.19 (0.17-0.21)

16 ECOTOX

Great Lakes Chemical Corp.

Acute Toxicity of Tetrabromobisphenol A to Fathead Minnow (Pimephales promelas) Under Flow-Through Conditions with Attachments and Cover Letter Dated 111788

EPA/OTS 40-8898095

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality

LC50

hours

>3～3.6

mg/L

16 ECOTOX

Lee,S.K., D. Freitag, C. Steinberg, A. Kettrup, and Y.H. Kim

Effects of Dissolved Humic Materials on Acute Toxicity of Some Organic Chemicals to Aquatic Organisms

Water Res.27(2)

2020/11/12

魚類

Danio rerio (Zebrafish)

Morphology//Abnormal

NOEC

114

hours

61.12

μM

0 uM / 0.0061 uM / 0.0611 uM / 0.6112 uM / 6.112 u

16 ECOTOX

Truong,L., D.M. Reif, L. St Mary, M.C. Geier, H.D. Truong, and R.L. Tanguay

Multidimensional In Vivo Hazard Assessment Using Zebrafish

Toxicol. Sci.137(1)

2020/11/12

魚類

Danio rerio (Zebrafish)

Morphology//Abnormal

NOEC

114

hours

61.12

μM

0 uM / 0.0061 uM / 0.0611 uM / 0.6112 uM / 6.112 u

16 ECOTOX

Truong,L., D.M. Reif, L. St Mary, M.C. Geier, H.D. Truong, and R.L. Tanguay

Multidimensional In Vivo Hazard Assessment Using Zebrafish

Toxicol. Sci.137(1)

2020/11/12

魚類

Oncorhynchus mykiss (Rainbow trout)

Mortality

LC50

hours

1.1

mg/L

19 その他

Blankinship AS, Van Hoven RL and Krueger HO

Tetrabromobisphenol-A: A 96-hour Flow-through Acute Toxicity Test with the Rainbow Trout (Oncorhynchus mykiss) Final Report.

Wildlife International, Ltd. Project Number: 439A-123. Wildlife International, Ltd., Easton, Maryland. 8 July 2003. Unpublished.

2021/05/14

魚類

Oncorhynchus mykiss (Rainbow trout)

Mortality

NR-LETH

hours

mg/L

0 mg/L / 0 mg/L / 0.10 mg/L / 0.18 mg/L / 0.32 mg/

16 ECOTOX

Great Lakes Chemical Corp.

Acute Toxicity of FMBP4A (Tetrabromobisphenol A) to the Rainbow Trout, Salmo gairdneri Richardson

EPA/OTS 878216107

2020/11/12

魚類

Oncorhynchus mykiss (Rainbow trout)

Multiple effects

NOEC

hours

0.1

mg/L

0 mg/L / 0 mg/L / 0.10 mg/L / 0.18 mg/L / 0.32 mg/

16 ECOTOX

Great Lakes Chemical Corp.

Acute Toxicity of FMBP4A (Tetrabromobisphenol A) to the Rainbow Trout, Salmo gairdneri Richardson

EPA/OTS 878216107

2020/11/12

魚類

Cyprinus carpio (Carp)

Mortality

LC50

hours

0.71

mg/L

19 その他

ECHA

European Chemicals Agency. Substance Evaluation.

Agency of the European Union, Helsinki, Finland. http://echa.europa.eu/regulations/reach/evaluation/substance- evaluation (accessed on Februrary 10, 2019).

2021/05/14

魚類

Oncorhynchus mykiss (Rainbow trout)

NOEC

hours

0.18

mg/L

19 その他

Calmbacher CW

The acute toxicity of FMBP4A (tetrabromobisphenol A) to the rainbow trout, Salmo gairdneri Richardson.

Tarrytown, New York, Union Carbide Corporation, Environmental Services (Report to Velsicol Chemical Corporation, Chicago, submitted to WHO by the Brominated Flame Retardant Industry Panel). Cited in WHO (1995) but not sighted for the present assessment.

2021/04/14

魚類

Oncorhynchus mykiss (Rainbow trout)

Multiple effects

LOEC

hours

0.18

mg/L

0 mg/L / 0 mg/L / 0.10 mg/L / 0.18 mg/L / 0.32 mg/

16 ECOTOX

Great Lakes Chemical Corp.

Acute Toxicity of FMBP4A (Tetrabromobisphenol A) to the Rainbow Trout, Salmo gairdneri Richardson

EPA/OTS 878216108

2020/11/12

魚類

Pimephales promelas

NOEC

144

hours

0.26

mg/L [TBBPA]

0.18, 0.27, 0.42, 0.65, 1.0 mg TBBPA/L

19 その他

Surprenant DC

Acute toxicity of Tetrabromobisphenol A to Fathead Minnow (Pimephales promelas) under Flow-through Conditions.

SLS Report #88-10-2834, SLS Study #1199.1287.6104.106. Springborn Life Sciences, Inc., Wareham, Massachusetts. 16 November 1988. Unpublished

2021/05/14

魚類

Danio rerio (Zebrafish)

Mortality

LC50

hours

1.3

mg/L [TBBPA]

from 0.625 to 5 mg/L

19 その他

Godfrey A, Abdel-moneim A and Sepúlveda MS

Acute mixture toxicity of halogenated chemicals and their next generation counterparts on zebrafish embryos'

Chemosphere, 181

2021/05/14

魚類

Danio rerio (Zebrafish)

Mortality

LOEC

days

1.63

mg/L

19 その他

Kuiper R, Brandhof E, Leonards P, Ven L, Wester P and Vos J

Toxicity of tetrabromobisphenol A (TBBPA) in zebrafish (Danio rerio) in a partial life-cycle test

Archives of Toxicology, 81

2021/04/13

魚類

Danio rerio (Zebrafish)

Mortality

LOELR

144

hours

500

μg/L [TBBPA]

500, 1000, 1500 µｇ TBBPA/L

19 その他

Song M, Liang D, Liang Y, Chen M, Wang F, Wang H and Jiang G

Assessing developmental toxicity and oestrogenic activity of halogenated bisphenol A on zebrafish (Danio rerio)

Chemosphere, 112

2021/05/14

魚類

Danio rerio (Zebrafish)

Behavior//Distance moved, change in direct movement

LOEL

2.5

hours

1.2

μM

0 uM / 0 uM / 0 uM / 1.2 uM / 2.1 uM / 3.8 uM / 6.

16 ECOTOX

Jarema,K.A., D.L. Hunter, R.M. Shaffer, M. Behl, and S. Padilla

Acute and Developmental Behavioral Effects of Flame Retardants and Related Chemicals in Zebrafish

Neurotoxicol. Teratol.52

2020/11/12

魚類

Danio rerio (Zebrafish)

Behavior//Escape response

NOEC

114

hours

61.12

μM

0 uM / 0.0061 uM / 0.0611 uM / 0.6112 uM / 6.112 u

16 ECOTOX

Truong,L., D.M. Reif, L. St Mary, M.C. Geier, H.D. Truong, and R.L. Tanguay

Multidimensional In Vivo Hazard Assessment Using Zebrafish

Toxicol. Sci.137(1)

2020/11/12

魚類

Danio rerio (Zebrafish)

Morphology//Abnormal

NOEC

114

hours

61.12

μM

0 uM / 0.0061 uM / 0.0611 uM / 0.6112 uM / 6.112 u

16 ECOTOX

Truong,L., D.M. Reif, L. St Mary, M.C. Geier, H.D. Truong, and R.L. Tanguay

Multidimensional In Vivo Hazard Assessment Using Zebrafish

Toxicol. Sci.137(1)

2020/11/12

魚類

Lepomis macrochirus

NOEC

hours

0.1

mg/L

19 その他

Calmbacher

The acute toxicity of FMBP4A (tetrabromobisphenol A) to the bluegill sunfish, Lepomis macrochirus Rafinesque.

2021/04/14

魚類

Danio rerio (Zebrafish)

Morphology//Abnormal

NOEC

114

hours

61.12

μM

0 uM / 0.0061 uM / 0.0611 uM / 0.6112 uM / 6.112 u

16 ECOTOX

Truong,L., D.M. Reif, L. St Mary, M.C. Geier, H.D. Truong, and R.L. Tanguay

Multidimensional In Vivo Hazard Assessment Using Zebrafish

Toxicol. Sci.137(1)

2020/11/12

魚類

Danio rerio (Zebrafish)

Morphology//Abnormal

NOEC

114

hours

61.12

μM

0 uM / 0.0061 uM / 0.0611 uM / 0.6112 uM / 6.112 u

16 ECOTOX

Truong,L., D.M. Reif, L. St Mary, M.C. Geier, H.D. Truong, and R.L. Tanguay

Multidimensional In Vivo Hazard Assessment Using Zebrafish

Toxicol. Sci.137(1)

2020/11/12

魚類

Danio rerio (Zebrafish)

Morphology//Abnormal

NOEC

114

hours

61.12

μM

0 uM / 0.0061 uM / 0.0611 uM / 0.6112 uM / 6.112 u

16 ECOTOX

Truong,L., D.M. Reif, L. St Mary, M.C. Geier, H.D. Truong, and R.L. Tanguay

Multidimensional In Vivo Hazard Assessment Using Zebrafish

Toxicol. Sci.137(1)

2020/11/12

魚類

Danio rerio (Zebrafish)

Morphology//Abnormal

NOEC

114

hours

61.12

μM

0 uM / 0.0061 uM / 0.0611 uM / 0.6112 uM / 6.112 u

16 ECOTOX

Truong,L., D.M. Reif, L. St Mary, M.C. Geier, H.D. Truong, and R.L. Tanguay

Multidimensional In Vivo Hazard Assessment Using Zebrafish

Toxicol. Sci.137(1)

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality

LC50

144

hours

1240

μg/L [TBBPA]

500, 1000, 1500 µｇ TBBPA/L

19 その他

Song M, Liang D, Liang Y, Chen M, Wang F, Wang H and Jiang G

Assessing developmental toxicity and oestrogenic activity of halogenated bisphenol A on zebrafish (Danio rerio)

Chemosphere, 112

2021/05/14

魚類

Danio rerio (Zebrafish)

Morphology//Abnormal

NOEC

114

hours

61.12

μM

0 uM / 0.0061 uM / 0.0611 uM / 0.6112 uM / 6.112 u

16 ECOTOX

Truong,L., D.M. Reif, L. St Mary, M.C. Geier, H.D. Truong, and R.L. Tanguay

Multidimensional In Vivo Hazard Assessment Using Zebrafish

Toxicol. Sci.137(1)

2020/11/12

魚類

Oncorhynchus mykiss (Rainbow trout)

Mortality

LC50

hours

0.84

mg/L

0 mg/L / 0 mg/L / 0.10 mg/L / 0.18 mg/L / 0.32 mg/

16 ECOTOX

Great Lakes Chemical Corp.

Acute Toxicity of FMBP4A (Tetrabromobisphenol A) to the Rainbow Trout, Salmo gairdneri Richardson

EPA/OTS 878216108

2020/11/12

魚類

Carassius auratus (Goldfish)

Mortality

LC50

hours

3.134

mg/L

0 mg/L / 0 mg/L / 1.54 mg/L / 2.00 mg/L / 2.60 mg/

16 ECOTOX

Yang,S.W., Z.G. Yan, F.F. Xu, S.R. Wang, and F.C. Wu

Development of Freshwater Aquatic Life Criteria for Tetrabromobisphenol A in China

Environ. Pollut.169

2020/11/12

魚類

Lepomis macrochirus

Mortality

LC50

hours

0.51

mg/L

19 その他

IPCS

Environmental health criteria 172, Tetrabromobisphenol A and derivatives

Geneva, World Health Organization

2021/04/13

魚類

Lepomis macrochirus

Mortality

NR-ZERO

hours

0.32

mg/L

0 mg/L / 0 mg/L / 0.18 mg/L / 0.32 mg/L / 0.56 mg/

16 ECOTOX

Great Lakes Chemical Corp.

Acute Toxicity of FMBP4A (Tetrabromobisphenol A) to the Bluegill Sunfish, Lepomis macrochirus rafinesque

EPA/OTS 878216107

2020/11/12

魚類

Lepomis macrochirus

Mortality

NR-LETH

hours

mg/L

0 mg/L / 0 mg/L / 0.18 mg/L / 0.32 mg/L / 0.56 mg/

16 ECOTOX

Great Lakes Chemical Corp.

Acute Toxicity of FMBP4A (Tetrabromobisphenol A) to the Bluegill Sunfish, Lepomis macrochirus rafinesque

EPA/OTS 878216107

2020/11/12

魚類

Lepomis macrochirus

Behavior//Behavioral changes, general

NOEC

hours

0.18

mg/L

0 mg/L / 0 mg/L / 0.18 mg/L / 0.32 mg/L / 0.56 mg/

16 ECOTOX

Great Lakes Chemical Corp.

Acute Toxicity of FMBP4A (Tetrabromobisphenol A) to the Bluegill Sunfish, Lepomis macrochirus rafinesque

EPA/OTS 878216107

2020/11/12

魚類

Oncorhynchus mykiss (Rainbow trout)

Mortality

LC50

hours

0.4

mg/L

19 その他

IPCS

Environmental health criteria 172, Tetrabromobisphenol A and derivatives

Geneva, World Health Organization

2021/04/13

魚類

Lepomis macrochirus

Behavior//Behavioral changes, general

LOEC

hours

0.32

mg/L

0 mg/L / 0 mg/L / 0.18 mg/L / 0.32 mg/L / 0.56 mg/

16 ECOTOX

Great Lakes Chemical Corp.

Acute Toxicity of FMBP4A (Tetrabromobisphenol A) to the Bluegill Sunfish, Lepomis macrochirus rafinesque

EPA/OTS 878216107

2020/11/12

魚類

Pimephales promelas

Mortality

LOEC

144

hours

0.32

AI mg/L

<0.032 AI mg/L / <0.032 AI mg/L / 0.19 (0.17-0.21)

16 ECOTOX

Great Lakes Chemical Corp.

Acute Toxicity of Tetrabromobisphenol A to Fathead Minnow (Pimephales promelas) Under Flow-Through Conditions with Attachments and Cover Letter Dated 111788

EPA/OTS 40-8898095

2020/11/12

魚類

Danio rerio (Zebrafish)

Morphology//Abnormal

NOEC

114

hours

61.12

μM

0 uM / 0.0061 uM / 0.0611 uM / 0.6112 uM / 6.112 u

16 ECOTOX

Truong,L., D.M. Reif, L. St Mary, M.C. Geier, H.D. Truong, and R.L. Tanguay

Multidimensional In Vivo Hazard Assessment Using Zebrafish

Toxicol. Sci.137(1)

2020/11/12

魚類

Oryzias latipes (Japanese medaka)

Mortality

LC50

hours

mg/L

19 その他

CITI

Biodegradation and Bioaccumulation Data of Existing Chemicals Based on the CSCL.

Chemicals Inspection and Testing Institute, Tokyo, Japan

2021/04/13

魚類

Danio rerio (Zebrafish)

Morphology//Abnormal

NOEC

114

hours

61.12

μM

0 uM / 0.0061 uM / 0.0611 uM / 0.6112 uM / 6.112 u

16 ECOTOX

Truong,L., D.M. Reif, L. St Mary, M.C. Geier, H.D. Truong, and R.L. Tanguay

Multidimensional In Vivo Hazard Assessment Using Zebrafish

Toxicol. Sci.137(1)

2020/11/12

魚類

Danio rerio (Zebrafish)

Physiology//Pigmentation

NOEC

114

hours

61.12

μM

0 uM / 0.0061 uM / 0.0611 uM / 0.6112 uM / 6.112 u

16 ECOTOX

Truong,L., D.M. Reif, L. St Mary, M.C. Geier, H.D. Truong, and R.L. Tanguay

Multidimensional In Vivo Hazard Assessment Using Zebrafish

Toxicol. Sci.137(1)

2020/11/12

魚類

Danio rerio (Zebrafish)

Mortality

LOEC

114

hours

6.112

μM

0 uM / 0.0061 uM / 0.0611 uM / 0.6112 uM / 6.112 u

16 ECOTOX

Truong,L., D.M. Reif, L. St Mary, M.C. Geier, H.D. Truong, and R.L. Tanguay

Multidimensional In Vivo Hazard Assessment Using Zebrafish

Toxicol. Sci.137(1)

2020/11/12

魚類

Pimephales promelas

Mortality

LC50

144

hours

0.54

mg/L

19 その他

IPCS

Environmental health criteria 172, Tetrabromobisphenol A and derivatives

Geneva, World Health Organization

2021/04/13

魚類

Pimephales promelas (Fathead minnow)

Mortality

LC50

hours

1.06

mg/L

17 Aquatic OASIS (OECD QSAR Toolbox)

Russom, C.L., Bradbury, S.P., Broderius, S.J., Drummond, R.A. and Hammermeister, D.E.

PREDICTING MODES OF TOXIC ACTION FROM CHEMICAL STRUCTURE: ACUTE TOXICITY IN THE FATHEAD MINNOW (PIMEPHALES PROMELAS)

1997

2016/02/08

魚類

Oryzias latipes (Japanese medaka)

Mortality

LC50

hours

8.23

mg/L

17 Aquatic OASIS (OECD QSAR Toolbox)

Biodegradation and Bioaccumulation Data of Existing Chemicals Based on the CSCL Japan

1992

2016/02/08

魚類

Brachydanio rerio (Zebrafish)

Egg production and juvenile development

5～7

mg/kg lipid

0.013, 0.026, 0.051, 0.102, 0.204, 0.408, 0.816, 1.63, 3.26mg/l, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Kuiper R V, van den Brandhof E J, Leonards P E G, van der Ven L T M, Wester P W and Vos J G.

Toxicity of tetrabromobisphenol A (TBBPA) in zebrafish (Danio rerio) in a partial life-cycle test.

Arch. Toxicol., 81

2007

2019/12/27

魚類

NOEC

days

0.16

mg/L

4 OECD SIDS (HPVC)

2020/01/21

魚類

Pimephales promelas (Fathead minnow)

Hatching

NOEC

0.16

mg/L

0.024, 0.040, 0.084, 0.16, 0.31mg/l, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Laboratories

The toxicity of tetrabromobisphenol A (TBBPA) to fathead minnow (Pimephales promelas) embryos and larvae.

Report No 89-2-2937. Springborn Laboratories, Inc., Wareham, Massachusetts

1989

2019/12/27

魚類

Pimephales promelas (Fathead minnow)

Hatching

LOEC

0.31

mg/L

0.024, 0.040, 0.084, 0.16, 0.31mg/l, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Laboratories

The toxicity of tetrabromobisphenol A (TBBPA) to fathead minnow (Pimephales promelas) embryos and larvae.

Report No 89-2-2937. Springborn Laboratories, Inc., Wareham, Massachusetts

1989

2019/12/27

魚類

Pimephales promelas (Fathead minnow)

Larval survival

NOEC

days

0.16

mg/L

0.024, 0.040, 0.084, 0.16, 0.31mg/l, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Laboratories

The toxicity of tetrabromobisphenol A (TBBPA) to fathead minnow (Pimephales promelas) embryos and larvae.

Report No 89-2-2937. Springborn Laboratories, Inc., Wareham, Massachusetts

1989

2019/12/27

魚類

Pimephales promelas (Fathead minnow)

Growth

NOEC

days

>=0.16

mg/L

0.024, 0.040, 0.084, 0.16, 0.31mg/l, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Laboratories

The toxicity of tetrabromobisphenol A (TBBPA) to fathead minnow (Pimephales promelas) embryos and larvae.

Report No 89-2-2937. Springborn Laboratories, Inc., Wareham, Massachusetts

1989

2019/12/27

魚類

Pimephales promelas (Fathead minnow)

Survival

LOEC

days

310

μg/L

○

24, 40, 84, 160, 310µg/l

14 BUA Report

Great Lakes Chemical Corporation

The toxicity of tetrabromobisphenol A (TBBPA) to fathead minnow (Pimephales promelas) embryos and larvae. Springborn Laboratories, SLS Report: 89-2-2937

1989

2020/01/21

魚類

Pimephales promelas (Fathead minnow)

Survival 30 days after hatching

NOEC

days

160

μg/L

○

24, 40, 84, 160, 310µg/l

14 BUA Report

Great Lakes Chemical Corporation

The toxicity of tetrabromobisphenol A (TBBPA) to fathead minnow (Pimephales promelas) embryos and larvae. Springborn Laboratories, SLS Report: 89-2-2937

1989

2020/01/21

魚類

Pimephales promelas (Fathead minnow)

Larval survival

LOEC

days

0.31

mg/L

0.024, 0.040, 0.084, 0.16, 0.31mg/l, control, solvent control

7 EU Risk Assessment Report (EUリスク評価書）

Springborn Laboratories

The toxicity of tetrabromobisphenol A (TBBPA) to fathead minnow (Pimephales promelas) embryos and larvae.

Report No 89-2-2937. Springborn Laboratories, Inc., Wareham, Massachusetts

1989

2019/12/27

魚類

Pimephales promelas (Fathead minnow)

mortality

LOEC

days

0.31

mg/L

○

0.025, 0.05, 0.1, 0.2, 0.4 mg a.i./L

0.024, 0.04, 0.084, 0.16, 0.31 mg a.i./L

12 ECHA Information on Registered Substances

study report

1989

魚類

Pimephales promelas (Fathead minnow)

mortality

NOEC

days

0.16

mg/L

○

0.025, 0.05, 0.1, 0.2, 0.4 mg a.i./L

0.024, 0.04, 0.084, 0.16, 0.31 mg a.i./L

12 ECHA Information on Registered Substances

study report

1989

魚類

Pimephales promelas (Fathead minnow)

Growth (length and weight)

NOEC

days

>=0.16

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Springbom Laboratories

Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

1989

2016/03/04

魚類

Oryzias latipes (Japanese medaka)

死亡

LOEC

days

0.78

mg/L

11 Japan チャレンジプログラム

2,2-ビス［4-ヒドロキシ-3，5-ジブロモフェニル］プロパンのヒメダカ（Oryzias latipes)に対する延長毒性試験-21日間

EFP95005

2016/03/08

魚類

Oryzias latipes (Japanese medaka)

死亡

NOEC

days

0.26

mg/L

11 Japan チャレンジプログラム

2,2-ビス［4-ヒドロキシ-3，5-ジブロモフェニル］プロパンのヒメダカ（Oryzias latipes)に対する延長毒性試験-21日間

EFP95005

2016/03/08

魚類

Pimephales promelas (Fathead minnow)

Hatching

NOEC

0.16

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Springbom Laboratories

Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

1989

2016/03/04

魚類

Pimephales promelas (Fathead minnow)

Hatching

LOEC

0.31

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Springbom Laboratories

Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

1989

2016/03/04

魚類

Pimephales promelas (Fathead minnow)

mortality

NOEC

hours

0.26

mg/L

10 EHC (Environmental Health Criteria)

Surprenant DC

Acute toxicity of tetrabromobisphenol A to fathead minnow (Pimephales promelas) under flow-through conditions.

Wareham, Massachusetts, Springborn Life Sciences, Inc. (Report No. SLS 88-10-2834 submitted to WHO by the Brominated Flame Retardant Industry Panel).

1988

2016/03/04

魚類

Pimephales promelas (Fathead minnow)

adverse effects on embryo and larval survival

days

>0.16～<0.31

10 EHC (Environmental Health Criteria)

Surprenant DC

The toxicity of tetrabromobisphenol A (TBBPA) to fathead minnow (Pimephales promelas) embryos and larvae.

Wareham, Massachusetts, Springborn Life Sciences, Inc. (Report No. 89-2-2937 submitted to WHO by the Brominated Flame Retardant Industry Panel).

1989

2016/03/04

魚類

Pimephales promelas (Fathead minnow)

Larval survival

NOEC

days

0.16

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Springbom Laboratories

Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

1989

2016/03/04

魚類

Pimephales promelas (Fathead minnow)

Larval survival

LOEC

days

0.31

mg/L

7 EU Risk Assessment Report (EUリスク評価書）

Springbom Laboratories

Lake Superior Environmental Studies, University of Wisconsin, Superior, WI. As quoted in AQUIRE database.

1989

2016/03/04

魚類

Danio rerio (Zebrafish)

Development

LOEC

days

1.63

mg/L

19 その他

Kuiper R, Brandhof E, Leonards P, Ven L, Wester P and Vos J

Toxicity of tetrabromobisphenol A (TBBPA) in zebrafish (Danio rerio) in a partial life-cycle test.

Archives of Toxicology, 81

2021/04/13

魚類

Danio rerio (Zebrafish)

Development//Slowed, Retarded, Delayed or Non-development

LOEC

days

μM

0 uM / 0.023 uM / 0.047 uM / 0.094 uM / 0.188 uM /

16 ECOTOX

Kuiper,R.V., E.J. Van den Brandhof, P.E.G. Leonards, L.T.M. van der Ven, P.W. Wester, and J.G. Vos

Toxicity of Tetrabromobisphenol A (TBBPA) in Zebrafish (Danio rerio) in a Partial Life-Cycle Test

Arch. Toxicol.81(1)

2020/11/12

魚類

Danio rerio (Zebrafish)

Hatching

LOEC

days

0.013

mg/L

19 その他

Kuiper R, Brandhof E, Leonards P, Ven L, Wester P and Vos J

Toxicity of tetrabromobisphenol A (TBBPA) in zebrafish (Danio rerio) in a partial life-cycle test.

Archives of Toxicology, 81

2021/04/13

魚類

Danio rerio (Zebrafish)

Egg production

LOEC

days

0.047

mg/L

19 その他

Kuiper R, Brandhof E, Leonards P, Ven L, Wester P and Vos J

Toxicity of tetrabromobisphenol A (TBBPA) in zebrafish (Danio rerio) in a partial life-cycle test.

Archives of Toxicology, 81

2021/04/13

魚類

Pimephales promelas

Survival

LOEC

days

0.31

AI mg/L

<0.0089-<0.0090 AI mg/L / <0.0089-0.24 AI mg/L / 0

16 ECOTOX

Great Lakes Chemical Corp.

Bioconcentration and Elimination of C-Residues by Eastern Oysters (Crassostrea virginica) Exposed to Tetrabromobisphenol A (Final Report) with Attached Studies & Letter 081889

EPA/OTS 40-8998118

2020/11/12

魚類

Pimephales promelas

Embryo survival

LOEC

days

0.31

mg/L

19 その他

Brominated Flame Retardants Industry Panel

The toxicity of tetrabromobisphenol A (TBBPA) to fathead minnow (Pimephales promelas) embryos and larvae.

Springborn Laboratories, Inc. Report #89-2-2937, Study #1199-1287-6108-120. August 17, 1989.

2021/04/13

魚類

Pimephales promelas

NOEC

days

0.16

mg/L

from 0.024 to 0.31 mg/L

19 その他

IPCS

Environmental health criteria 172, Tetrabromobisphenol A and derivatives

Geneva, World Health Organization

2021/04/13

魚類

Pimephales promelas

MATC

days

0.16～0.31

mg/L

from 0.024 to 0.31 mg/L

19 その他

IPCS

Environmental health criteria 172, Tetrabromobisphenol A and derivatives

Geneva, World Health Organization

2021/04/13

魚類

Pimephales promelas

Embryo survival

LOEC

days

0.31

mg/L

19 その他

Brominated Flame Retardants Industry Panel

The toxicity of tetrabromobisphenol A (TBBPA) to fathead minnow (Pimephales promelas) embryos and larvae.

Springborn Laboratories, Inc. Report #89-2-2937, Study #1199-1287-6108-120. August 17, 1989.

2021/04/13

魚類

Danio rerio (Zebrafish)

Survival

LOEC

weeks

1.5

μM

0 uM / 0.023 uM / 0.047 uM / 0.094 uM / 0.188 uM /

16 ECOTOX

Kuiper,R.V., E.J. Van den Brandhof, P.E.G. Leonards, L.T.M. van der Ven, P.W. Wester, and J.G. Vos

Toxicity of Tetrabromobisphenol A (TBBPA) in Zebrafish (Danio rerio) in a Partial Life-Cycle Test

Arch. Toxicol.81(1)

2020/11/12

魚類

Danio rerio (Zebrafish)

Population//Sex ratio

LOEC

days

1.5

μM

0 uM / 0.023 uM / 0.047 uM / 0.094 uM / 0.188 uM /

16 ECOTOX

Kuiper,R.V., E.J. Van den Brandhof, P.E.G. Leonards, L.T.M. van der Ven, P.W. Wester, and J.G. Vos

Toxicity of Tetrabromobisphenol A (TBBPA) in Zebrafish (Danio rerio) in a Partial Life-Cycle Test

Arch. Toxicol.81(1)

2020/11/12

魚類

Danio rerio (Zebrafish)

Survival

NOEC

weeks

0.375

μM

0 uM / 0.023 uM / 0.047 uM / 0.094 uM / 0.188 uM /

16 ECOTOX

Kuiper,R.V., E.J. Van den Brandhof, P.E.G. Leonards, L.T.M. van der Ven, P.W. Wester, and J.G. Vos

Toxicity of Tetrabromobisphenol A (TBBPA) in Zebrafish (Danio rerio) in a Partial Life-Cycle Test

Arch. Toxicol.81(1)

2020/11/12

魚類

Danio rerio (Zebrafish)

Population//Sex ratio

NOEC

days

0.375

μM

0 uM / 0.023 uM / 0.047 uM / 0.094 uM / 0.188 uM /

16 ECOTOX

Kuiper,R.V., E.J. Van den Brandhof, P.E.G. Leonards, L.T.M. van der Ven, P.W. Wester, and J.G. Vos

Toxicity of Tetrabromobisphenol A (TBBPA) in Zebrafish (Danio rerio) in a Partial Life-Cycle Test

Arch. Toxicol.81(1)

2020/11/12

魚類

Pimephales promelas

Survival

NOEC

days

0.16

AI mg/L

<0.0089-<0.0090 AI mg/L / <0.0089-0.24 AI mg/L / 0

16 ECOTOX

Great Lakes Chemical Corp.

Bioconcentration and Elimination of C-Residues by Eastern Oysters (Crassostrea virginica) Exposed to Tetrabromobisphenol A (Final Report) with Attached Studies & Letter 081889

EPA/OTS 40-8998118

2020/11/12

魚類

Carassius auratus (Goldfish)

Mortality//Lifespan

EC10

days

0.522

mg/L

0 mg/L / 0 mg/L / 0.4 mg/L / 0.52 mg/L / 0.68 mg/L

16 ECOTOX

Yang,S.W., Z.G. Yan, F.F. Xu, S.R. Wang, and F.C. Wu

Development of Freshwater Aquatic Life Criteria for Tetrabromobisphenol A in China

Environ. Pollut.169

2020/11/12

魚類

NOEC

days

0.16

mg/L

19 その他

US EPA

Flame retardants in printed circuit boards.

Final report, August 2015 EPA Publication 744-R-15-001. https://www.epa.gov/sites/production/files/2015-08/documents/pcb_final_report.pdf.

2021/04/14

魚類

Danio rerio (Zebrafish)

Development//Slowed, Retarded, Delayed or Non-development

NOEC

days

1.5

μM

0 uM / 0.023 uM / 0.047 uM / 0.094 uM / 0.188 uM /

16 ECOTOX

Kuiper,R.V., E.J. Van den Brandhof, P.E.G. Leonards, L.T.M. van der Ven, P.W. Wester, and J.G. Vos

Toxicity of Tetrabromobisphenol A (TBBPA) in Zebrafish (Danio rerio) in a Partial Life-Cycle Test

Arch. Toxicol.81(1)

2020/11/12

魚類

Pimephales promelas

Survival

MATC

days

0.22

AI mg/L

<0.0089-<0.0090 AI mg/L / <0.0089-0.24 AI mg/L / 0

16 ECOTOX

Great Lakes Chemical Corp.

Bioconcentration and Elimination of C-Residues by Eastern Oysters (Crassostrea virginica) Exposed to Tetrabromobisphenol A (Final Report) with Attached Studies & Letter 081889

EPA/OTS 40-8998118

2020/11/12

魚類

Pimephales promelas

Survival

MATC

days

0.22

AI mg/L

<0.0089-<0.0090 AI mg/L / <0.0089-0.24 AI mg/L / 0

16 ECOTOX

Great Lakes Chemical Corp.

Bioconcentration and Elimination of C-Residues by Eastern Oysters (Crassostrea virginica) Exposed to Tetrabromobisphenol A (Final Report) with Attached Studies & Letter 081889

EPA/OTS 40-8998118

2020/11/12

その他

NOEC

days

125

mg/kg dry weight

4 OECD SIDS (HPVC)

2020/01/17

化学物質有害性情報データベース 物質情報

化学物質有害性情報データベース物質情報