化学物質有害性情報データベース 物質情報

CAS 登録番号 CAS RN® ： 85449
官報公示整理番号　METI No. ： 6-649
物質名 test material ： イソベンゾフラン－１，３－ジオン　／Isobenzofuran-1,3-dione
水溶解度 water solubility ：
LogKow ： 1.6 (実測値 measured)
備考 remarks ：
Excelファイルダウンロード (XLS:25KB)

【注意事項】
* 化学物質有害性情報データベース情報更新日が2019年9月以前はRead-acrossデータでも○としていないので、毒性値の取り扱いには注意が必要である。

　　　 　　　 　　　 　　　 　　　 　　　
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) Read-across * QSAR GLP 設定濃度 実測濃度 情報源 情報源による信頼性評価 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure duration value exposure duration unit toxicity value toxicity unit Read-across QSAR GLPnominal concentration measured concentrationoriginal work type original work reliability rankauthor title referenced journal publication year Information update date
藻類 Pseudokirchneriella subcapitata Population EC50 4 days 78530 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bollman,M.A., W.K. Baune, S. Smith, K. DeWhitt, and L. Kapustka Report on Algal Toxicity Tests on Selected Office of Toxic Substances (OTS) Chemicals EPA 600/3-90-041, U.S.EPA, Corvallis, OR:186 p. 1989 2016/03/25
藻類 Pseudokirchneriella subcapitata Population EC50 4 days 41400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bollman,M.A., W.K. Baune, S. Smith, K. DeWhitt, and L. Kapustka Report on Algal Toxicity Tests on Selected Office of Toxic Substances (OTS) Chemicals EPA 600/3-90-041, U.S.EPA, Corvallis, OR:186 p. 1989 2016/03/25
藻類 Pseudokirchneriella subcapitata Population EC50 4 days 147 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bollman,M.A., W.K. Baune, S. Smith, K. DeWhitt, and L. Kapustka Report on Algal Toxicity Tests on Selected Office of Toxic Substances (OTS) Chemicals EPA 600/3-90-041, U.S.EPA, Corvallis, OR:186 p. 1989 2016/03/25
藻類 Pseudokirchneriella subcapitata EC50 72 hours 68 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版） 2016/11/09
藻類 Pseudokirchneriella subcapitata EC50 72 hours 48 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版） 2016/11/09
藻類 Selenastrum capricornutum 生長阻害 EbC50 72 hours 48 mg/L 11 Japan チャレンジプログラム - 無水フタル酸の藻類（Selenastrum capricornutum)に対する生長阻害試験 第15031号 2016/03/07
藻類 Selenastrum capricornutum 生長阻害　24-48h ErC50 72 hours 60 mg/L 11 Japan チャレンジプログラム - 無水フタル酸の藻類（Selenastrum capricornutum)に対する生長阻害試験 第15031号 2016/03/07
藻類 Selenastrum capricornutum 生長阻害　 EC0 72 hours >=100 mg/L ○ 11 Japan チャレンジプログラム 1 Bayer Industry Services Internal report: "Algal growth inhibition test of Phthalic acid" GLP-No. 1317 A/04 Al 2004 2016/03/07
藻類 Selenastrum capricornutum 生長阻害　24-72h ErC50 72 hours 60 mg/L 11 Japan チャレンジプログラム - 無水フタル酸の藻類（Selenastrum capricornutum)に対する生長阻害試験 第15031号 2016/03/07
藻類 Selenastrum capricornutum 生長阻害　 EC100 72 hours 100 mg/L ○ 11 Japan チャレンジプログラム 1 Bayer Industry Services Internal report: "Algal growth inhibition test of Phthalic acid" GLP-No. 1317 A/04 Al 2004 2016/03/07
藻類 Desmodesmus sp. growth rate EC50 72 hours >=100 mg/L 4 OECD SIDS (HPVC) 1 Bayer Industry Services Internal report: "Algal growth inhibition test of Phthalic acid" 2004 2016/02/22
藻類 Selenastrum capricornutum biomass EC50 96 hours 4.14 mg/L 4 OECD SIDS (HPVC) 3 Bollman MA, Baune WK, Smith S, DeWhitt K, Kapustka L Report on algal toxicity tests on selected office of toxic substances (OTS) chemicals 1989 2016/02/22
藻類 Scenedesmus sp. Scenedesmus subspicatus CHODAT biomass EC50 7 days 506 mg/L 4 OECD SIDS (HPVC) 3 Bayer Industry Services Internal communication with Bricelj M, email dated from 2004-03-29 2004 2016/02/22
藻類 Scenedesmus sp. Scenedesmus subspicatus CHODAT growth rate EC50 7 days 258 mg/L 4 OECD SIDS (HPVC) 3 Bayer Industry Services Internal communication with Bricelj M, email dated from 2004-03-29 2004 2016/02/22
藻類 Desmodesmus subspicatus growth rate EC0 72 hours >=100 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2004 2016/03/18
藻類 Pseudokirchneriella subcapitata growth rate EC50 72 hours 68 mg/L ○ 12 ECHA Information on Registered Substances 2 review article or handbook 2003 2016/03/17
藻類 Scenedesmus subspicatus growth rate EC50 7 days 258 mg/L 12 ECHA Information on Registered Substances 3 Sepic E, Bricelj M, Leskovsek H Toxicity of fluoranthene and its biodegradation metabolites to aquatic organisms Chemosphere 2003 2016/03/17
藻類 Pseudokirchneriella subcapitata biomass EC50 96 hours 4.14 mg/L 12 ECHA Information on Registered Substances 3 Bollman MA, Baune WK, Smith S, DeWhitt K, Kapustka L Report on algal toxicity tests on selected office of toxic substances (OTS) chemicals. USEPA Environmental Research Laboratory US-EPA 1989 2016/03/17
藻類 Pseudokirchneriella subcapitata NOEC 72 hours 9.5 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版） 2016/11/09
藻類 Pseudokirchneriella subcapitata NOEC 72 hours 32 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版） 2016/11/09
藻類 Selenastrum capricornutum 生長阻害　24-72h NOErC 72 hours 32 mg/L 11 Japan チャレンジプログラム - 無水フタル酸の藻類（Selenastrum capricornutum)に対する生長阻害試験 第15031号 2016/03/07
藻類 Selenastrum capricornutum 生長阻害 NOEbC 72 hours 9.5 mg/L 11 Japan チャレンジプログラム - 無水フタル酸の藻類（Selenastrum capricornutum)に対する生長阻害試験 第15031号 2016/03/07
藻類 Selenastrum capricornutum 生長阻害　24-48h NOErC 72 hours 32 mg/L 11 Japan チャレンジプログラム - 無水フタル酸の藻類（Selenastrum capricornutum)に対する生長阻害試験 第15031号 2016/03/07
藻類 Pseudokirchneriella subcapitata growth rate 72 hours 32 mg/L ○ 12 ECHA Information on Registered Substances 2 review article or handbook 2003 2016/03/17
藻類 Desmodesmus subspicatus growth rate 72 hours >=100 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2004 2016/03/18
甲殻類 Daphnia magna EC50 48 hours 71 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版） 2016/11/09
甲殻類 Daphnia magna 遊泳阻害 EiC100 48 hours 82 mg/L 11 Japan チャレンジプログラム - 無水フタル酸のオオミジンコ（Daphnia magna)に対する急性遊泳阻害試験 第15032号 2016/03/07
甲殻類 Daphnia magna 遊泳阻害 EC50 48 hours >640 mg/L 11 Japan チャレンジプログラム 2 Adams WJ, Renaudette WJ Experimental freshwater microcosm biodegradability study of butyl benzyl phthalate EPA/OTS Document no. 0510751 1986 2016/03/07
甲殻類 Daphnia magna 遊泳阻害 EiC0 24 hours 61 mg/L 11 Japan チャレンジプログラム - 無水フタル酸のオオミジンコ（Daphnia magna)に対する急性遊泳阻害試験 第15032号 2016/03/07
甲殻類 Daphnia magna 遊泳阻害 EC100 24 hours 180 mg/L 11 Japan チャレンジプログラム 2 Sepic E, Bricelj M, Leskovsek H Toxicity of fluoranthene and its biodegradation metabolites to aquatic organisms Chemosphere 52 2003 2016/03/07
甲殻類 Daphnia magna 遊泳阻害 EC0 24 hours 100 mg/L 11 Japan チャレンジプログラム 2 Sepic E, Bricelj M, Leskovsek H Toxicity of fluoranthene and its biodegradation metabolites to aquatic organisms Chemosphere 52 2003 2016/03/07
甲殻類 Daphnia magna 遊泳阻害 EiC50 48 hours 71 mg/L 11 Japan チャレンジプログラム - 無水フタル酸のオオミジンコ（Daphnia magna)に対する急性遊泳阻害試験 第15032号 2016/03/07
甲殻類 Daphnia magna 遊泳阻害 EC0 48 hours >=640 mg/L 11 Japan チャレンジプログラム 2 Adams WJ, Renaudette WJ Experimental freshwater microcosm biodegradability study of butyl benzyl phthalate EPA/OTS Document no. 0510751 1986 2016/03/07
甲殻類 Daphnia magna 遊泳阻害 EiC100 24 hours 110 mg/L 11 Japan チャレンジプログラム - 無水フタル酸のオオミジンコ（Daphnia magna)に対する急性遊泳阻害試験 第15032号 2016/03/07
甲殻類 Daphnia magna 遊泳阻害 EiC0 48 hours 61 mg/L 11 Japan チャレンジプログラム - 無水フタル酸のオオミジンコ（Daphnia magna)に対する急性遊泳阻害試験 第15032号 2016/03/07
甲殻類 Daphnia magna 遊泳阻害 EiC50 24 hours 86 mg/L 11 Japan チャレンジプログラム - 無水フタル酸のオオミジンコ（Daphnia magna)に対する急性遊泳阻害試験 第15032号 2016/03/07
甲殻類 Daphnia magna 遊泳阻害 IC50 24 hours 4370 mg/L 11 Japan チャレンジプログラム 2 Zhao YH, Ji GD, Cronin MTD, Dearden JC QSAR study of the toxicity of benzoic acids to Vibrio fisheri, Daphnia magna and carp. The Science of the Total Environment 216 1998 2016/03/07
甲殻類 Daphnia magna 遊泳阻害 IC50 24 hours 4900 mg/L 11 Japan チャレンジプログラム 2 Zhao YH, Ji GD, Cronin MTD, Dearden JC QSAR study of the toxicity of benzoic acids to Vibrio fisheri, Daphnia magna and carp. The Science of the Total Environment 216 1998 2016/03/07
甲殻類 Daphnia magna 遊泳阻害 EC50 24 hours 140 mg/L 11 Japan チャレンジプログラム 2 Sepic E, Bricelj M, Leskovsek H Toxicity of fluoranthene and its biodegradation metabolites to aquatic organisms Chemosphere 52 2003 2016/03/07
甲殻類 Daphnia magna 遊泳阻害 IC50 24 hours 6460 mg/L 11 Japan チャレンジプログラム 2 Zhao YH, Ji GD, Cronin MTD, Dearden JC QSAR study of the toxicity of benzoic acids to Vibrio fisheri, Daphnia magna and carp. The Science of the Total Environment 216 1998 2016/03/07
甲殻類 Daphnia magna EC0 48 hours >=640 mg/L 4 OECD SIDS (HPVC) 2 Adams WJ, Renaudette WJ Experimental freshwater microcosm biodegradability study of butyl benzyl phthalate. EPA/OTS Document 1986 2016/02/22
甲殻類 Daphnia magna immobilization EC50 24 hours 4370 mg/L 4 OECD SIDS (HPVC) 2 Zhao YH, Ji GD, Cronin MTD, Dearden JC QSAR study of the toxicity of benzoic acids to Vibrio fisheri, Daphnia magna and carp he Science of the Total Environment 1998 2016/02/22
甲殻類 Daphnia magna immobilization EC50 24 hours 4900 mg/L 4 OECD SIDS (HPVC) 2 Zhao YH, Ji GD, Cronin MTD, Dearden JC QSAR study of the toxicity of benzoic acids to Vibrio fisheri, Daphnia magna and carp he Science of the Total Environment 1998 2016/02/22
甲殻類 Daphnia magna EC50 24 hours 140 mg/L 4 OECD SIDS (HPVC) 2 Sepic E, Bricelj M, Leskovsek H Toxicity of fluoranthene and its biodegradation metabolites to aquatic organisms Chemosphere 2003 2016/02/22
甲殻類 Daphnia magna EC50 48 hours >640 mg/L 4 OECD SIDS (HPVC) 2 Adams WJ, Renaudette WJ Experimental freshwater microcosm biodegradability study of butyl benzyl phthalate. EPA/OTS Document 1986 2016/02/22
甲殻類 Daphnia magna immobilization EC50 24 hours 6460 mg/L 4 OECD SIDS (HPVC) 2 Zhao YH, Ji GD, Cronin MTD, Dearden JC QSAR study of the toxicity of benzoic acids to Vibrio fisheri, Daphnia magna and carp he Science of the Total Environment 1998 2016/02/22
甲殻類 Daphnia magna mobility EC0 48 hours >=640 mg/L ○ 12 ECHA Information on Registered Substances 2 publication 1986 2016/03/17
甲殻類 Daphnia magna mobility EC50 48 hours >640 mg/L ○ 12 ECHA Information on Registered Substances 2 publication 1986 2016/03/17
甲殻類 Daphnia magna immobilization EC50 48 hours 71 mg/L ○ 12 ECHA Information on Registered Substances 2 review article or handbook 2003 2016/03/17
甲殻類 Daphnia magna mobility IC50 24 hours 4900 mg/L 12 ECHA Information on Registered Substances 3 Zhao YH, Ji GD, Cronin MTD, Dearden JC QSAR study of the toxicity of benzoic　acids to Vibrio fisheri, Daphnia magna and carp. The Science of the Total Environment 1998 2016/03/17
甲殻類 Daphnia magna mobility LC50 24 hours 140 mg/L 12 ECHA Information on Registered Substances 3 Sepic E, Bricelj M, Leskovsek H Toxicity of fluoranthene and its biodegradation metabolites to aquatic organisms. Chemosphere 2003 2016/03/17
甲殻類 Daphnia magna NOEC 21 days 16 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版） 2016/11/09
甲殻類 Daphnia magna EC50 21 days 42 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版） 2016/11/09
甲殻類 Daphnia magna 繁殖 NOEC 21 days 16 mg/L 11 Japan チャレンジプログラム - 無水フタル酸のオオミジンコ（Daphnia magna)に対する繁殖阻害試験 第15033号 2016/03/07
甲殻類 Daphnia magna 繁殖 EC50 21 days 42 mg/L 11 Japan チャレンジプログラム - 無水フタル酸のオオミジンコ（Daphnia magna)に対する繁殖阻害試験 第15033号 2016/03/07
甲殻類 Daphnia magna 親ミジンコの死亡 LC50 21 days 55 mg/L 11 Japan チャレンジプログラム - 無水フタル酸のオオミジンコ（Daphnia magna)に対する繁殖阻害試験 第15033号 2016/03/07
甲殻類 Daphnia magna 繁殖 LOEC 21 days 25 mg/L 11 Japan チャレンジプログラム - 無水フタル酸のオオミジンコ（Daphnia magna)に対する繁殖阻害試験 第15033号 2016/03/07
甲殻類 Daphnia magna reproduction EC50 21 days 42 mg/L ○ 12 ECHA Information on Registered Substances 2 review article or handbook 2003 2016/03/17
甲殻類 Daphnia magna reproduction 21 days 16 mg/L ○ 12 ECHA Information on Registered Substances 2 review article or handbook 2003 2016/03/17
魚類 Oncorhynchus mykiss (Rainbow trout) No Group Code LOEC 60 days 32000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Growth EC50 60 days 44100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LOEC 7 days 1000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2016/03/25
魚類 Danio rerio (Zebrafish) Growth EC50 7 days 561000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2016/03/25
魚類 Danio rerio (Zebrafish) No Group Code LOEC 7 days 1000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Growth LOEC 60 days 32000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Growth LOEC 60 days 32000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LOEC 60 days 32000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 60 days 44200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC0 2 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Lysak,A., and J. Marcinek Multiple Toxic Effect of Simultaneous Action of Some Chemical Substances on Fish Rocz. Nauk Roln. Ser. H Rybactwo.94(3): 53-63 1972 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 7 days 560000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2016/03/25
魚類 Oryzias latipes (Japanese medaka) LC50 96 hours >99 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版） 2016/11/09
魚類 Danio rerio (Zebrafish) 死亡 LC50 7 days 560 mg/L 11 Japan チャレンジプログラム 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds. Ecotoxicology and Environmental Safety 20 (1) 1990 2016/03/07
魚類 Danio rerio (Zebrafish) 胚毒性 EC50 7 days 561 mg/L 11 Japan チャレンジプログラム 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds. Ecotoxicology and Environmental Safety 20 (1) 1990 2016/03/07
魚類 Oryzias latipes (Japanese medaka) 死亡 LC100 96 hours >=99 mg/L 11 Japan チャレンジプログラム - 無水フタル酸のヒメダカ〔Oryzias latipes)に対する急性毒性試験 第15034号 2016/03/07
魚類 Oryzias latipes (Japanese medaka) 死亡 LC50 96 hours >=99 mg/L 11 Japan チャレンジプログラム - 無水フタル酸のヒメダカ〔Oryzias latipes)に対する急性毒性試験 第15034号 2016/03/07
魚類 Oryzias latipes (Japanese medaka) 死亡 LC0 96 hours 74 mg/L 11 Japan チャレンジプログラム - 無水フタル酸のヒメダカ〔Oryzias latipes)に対する急性毒性試験 第15034号 2016/03/07
魚類 Cyprinus carpio (Carp) 死亡 LC50 48 hours >500 mg/L × 11 Japan チャレンジプログラム 2 Zhao YH, Ji GD, Cronin MTD, Dearden JC QSAR study of the toxicity of benzoic acids to Vibrio fisheri, Daphnia magna and carp The Science of the Total Environment 216 1998 2016/03/07
魚類 Brachydanio rerio (Zebrafish) LC50 7 days 560 mg/L 4 OECD SIDS (HPVC) 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds Ecotoxicology and Environmental Safety 1990 2016/02/19
魚類 Brachydanio rerio (Zebrafish) total embryotoxicity EC50 7 days 561 mg/L 4 OECD SIDS (HPVC) 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds Ecotoxicology and Environmental Safety 1990 2016/02/19
魚類 Cyprinus carpio (Carp) LC50 48 hours >500 mg/L 4 OECD SIDS (HPVC) 2 Zhao YH, Ji GD, Cronin MTD, Dearden JC study of the toxicity of benzoic acids to Vibrio fisheri, Daphnia magna and carp The Science of the Total Environment 1998 2016/02/19
魚類 Leuciscus idus (Orfe) LC0 48 hours 100 mg/L 4 OECD SIDS (HPVC) 4 Bayer AG Internal information card of Phthalic anhydride 1973 2016/02/22
魚類 Leuciscus idus (Orfe) LC100 48 hours 200 mg/L 4 OECD SIDS (HPVC) 4 Bayer AG Internal information card of Phthalic anhydride 1973 2016/02/22
魚類 Oryzias latipes (Japanese medaka) LC50 48 hours >1000 mg/L 4 OECD SIDS (HPVC) 4 Tsuji S, Tonogai Y, Ito Y, Kanoh S The influence of rearing temperatures on the toxicity of various environmental pollutants for killifish (Oryzias latipes) J Hyg Chem/Eisei Kagaku 1986 2016/02/19
魚類 Oncorhynchus mykiss (Rainbow trout) 48 hours 5 mg/L 4 OECD SIDS (HPVC) 4 Lysak A, Marcinek J Multiple toxic effect of simultaneous action of some chemical substances on fish Roczniki Nauk Rolniczych 1972 2016/02/22
魚類 Leuciscus idus (Orfe) LC100 48 hours 360 mg/L 4 OECD SIDS (HPVC) 4 Huels AG Oekotoxikologische Pruefung des Produktes PHTHALSAEUREANHYDRID auf seine Wirkung im akuten Toxizitaetstest mit Goldorfen nach DIN 38412 Teil 15 Internal data, report no. 1982 2016/02/22
魚類 Leuciscus idus (Orfe) LC50 48 hours 313 mg/L 4 OECD SIDS (HPVC) 4 Huels AG Oekotoxikologische Pruefung des Produktes PHTHALSAEUREANHYDRID auf seine Wirkung im akuten Toxizitaetstest mit Goldorfen nach DIN 38412 Teil 15 Internal data, report no. 1982 2016/02/22
魚類 Leuciscus idus (Orfe) LC0 48 hours 250 mg/L 4 OECD SIDS (HPVC) 4 Huels AG Oekotoxikologische Pruefung des Produktes PHTHALSAEUREANHYDRID auf seine Wirkung im akuten Toxizitaetstest mit Goldorfen nach DIN 38412 Teil 15 Internal data, report no. 1982 2016/02/22
魚類 Cyprinus carpio (Carp) mortality LC50 48 hours >500 mg/L × 12 ECHA Information on Registered Substances 2 Zhao YH, Ji GD, Cronin MTD, Dearden JC QSAR study of the toxicity of benzoic acids to Vibrio fisheri, Daphnia magna and carp. The Science of the Total Environment 1998 2016/03/17
魚類 Danio rerio (Zebrafish) mortality IC50 7 days 560 mg/L × 12 ECHA Information on Registered Substances 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds Ecotoxicology and Environmental Safety 1990 2016/03/17
魚類 Oryzias latipes (Japanese medaka) LC50 48 hours >1000 mg/L 12 ECHA Information on Registered Substances 4 Tsuji S, Tonogai Y, Ito Y, Kanoh S The influence of rearing temperatures on the toxicity of various environmental pollutants for killifish (Oryzias latipes). J Hyg　Chem/Eisei Kagaku 1986 2016/03/17
魚類 Leuciscus idus (Orfe) mortality LC100 48 hours 200 mg/L × 12 ECHA Information on Registered Substances 3 study report 1973 2016/03/17
魚類 Leuciscus idus (Orfe) LC0 48 hours 100 mg/L × 12 ECHA Information on Registered Substances 3 study report 1973 2016/03/17
魚類 Oryzias latipes (Japanese medaka) mortality LC50 96 hours >99 mg/L ○ 12 ECHA Information on Registered Substances 2 review article or handbook 2003 2016/03/17
魚類 Oncorhynchus mykiss (Rainbow trout) 体長 LOEC 60 days 32 mg/L 11 Japan チャレンジプログラム 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds. Ecotoxicology and Environmental Safety 20 (1) 1990 2016/03/07
魚類 Oncorhynchus mykiss (Rainbow trout) 死亡、胚毒性、体長、体重 NOEC 60 days 10 mg/L 11 Japan チャレンジプログラム 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds. Ecotoxicology and Environmental Safety 20 (1) 1990 2016/03/07
魚類 Oncorhynchus mykiss (Rainbow trout) 胚毒性 LOEC 60 days 32 mg/L 11 Japan チャレンジプログラム 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds. Ecotoxicology and Environmental Safety 20 (1) 1990 2016/03/07
魚類 Danio rerio (Zebrafish) 胚毒性 LOEC 7 days 1000 mg/L 11 Japan チャレンジプログラム 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds. Ecotoxicology and Environmental Safety 20 (1) 1990 2016/03/07
魚類 Oncorhynchus mykiss (Rainbow trout) 死亡 LOEC 60 days 32 mg/L 11 Japan チャレンジプログラム 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds. Ecotoxicology and Environmental Safety 20 (1) 1990 2016/03/07
魚類 Oncorhynchus mykiss (Rainbow trout) 死亡 LC50 60 days 44.2 mg/L 11 Japan チャレンジプログラム 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds. Ecotoxicology and Environmental Safety 20 (1) 1990 2016/03/07
魚類 Oncorhynchus mykiss (Rainbow trout) 体重 LOEC 60 days 32 mg/L 11 Japan チャレンジプログラム 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds. Ecotoxicology and Environmental Safety 20 (1) 1990 2016/03/07
魚類 Oncorhynchus mykiss (Rainbow trout) 胚毒性 EC50 60 days 44.1 mg/L 11 Japan チャレンジプログラム 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds. Ecotoxicology and Environmental Safety 20 (1) 1990 2016/03/07
魚類 Danio rerio (Zebrafish) 死亡 LOEC 7 days 1000 mg/L 11 Japan チャレンジプログラム 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds. Ecotoxicology and Environmental Safety 20 (1) 1990 2016/03/07
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality, Total Embryotoxicity LOEC 60 days 32 mg/L 4 OECD SIDS (HPVC) 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds Ecotoxicology and Environmental Safety 1990 2016/02/22
魚類 Oncorhynchus mykiss (Rainbow trout) Total Embryotoxicity EC50 60 days 44.1 mg/L 4 OECD SIDS (HPVC) 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds Ecotoxicology and Environmental Safety 1990 2016/02/22
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 60 days 44.2 mg/L 4 OECD SIDS (HPVC) 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds Ecotoxicology and Environmental Safety 1990 2016/02/22
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LOEC 60 days 32 mg/L 4 OECD SIDS (HPVC) 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds Ecotoxicology and Environmental Safety 1990 2016/02/22
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality, Total Embryotoxicity NOEC 60 days 10 mg/L 4 OECD SIDS (HPVC) 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds Ecotoxicology and Environmental Safety 1990 2016/02/22
魚類 Brachydanio rerio (Zebrafish) total embryotoxicity LOEC 7 days 1000 mg/L 4 OECD SIDS (HPVC) 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds Ecotoxicology and Environmental Safety 1990 2016/02/19
魚類 Brachydanio rerio (Zebrafish) mortality LOEC 7 days 1000 mg/L 4 OECD SIDS (HPVC) 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds Ecotoxicology and Environmental Safety 1990 2016/02/19
魚類 Oncorhynchus mykiss (Rainbow trout) total embryotoxicity LOEC 60 days 32 mg/L 4 OECD SIDS (HPVC) 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds Ecotoxicology and Environmental Safety 1990 2016/02/22
魚類 Oncorhynchus mykiss (Rainbow trout) mortality, lengh, weight, embryotoxicity 60 days 10 mg/L × 12 ECHA Information on Registered Substances 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds. Ecotoxicology and Environmental Safety 1990 2016/03/17
魚類 Oncorhynchus mykiss (Rainbow trout) total embryotoxicity 60 days 32 mg/L × 12 ECHA Information on Registered Substances 2 Van Leeuwen CJ, Grootelaar EMM, Niebeek G Fish embryos as teratogenicity screens: A comparison of embryotoxicity between fish and birds. Ecotoxicology and Environmental Safety 1990 2016/03/17