化学物質有害性情報データベース 物質情報

CAS 登録番号 CAS RN® ： 99763
官報公示整理番号　METI No. ： 3-2199
物質名 test material ： メチル＝４－ヒドロキシベンゾアート　／Methyl 4-hydroxybenzoate
水溶解度 water solubility ：
LogKow ： 1.96 (実測値 measured)
備考 remarks ：
Excelファイルダウンロード (XLS:18KB)

【注意事項】
* 化学物質有害性情報データベース情報更新日が2019年9月以前はRead-acrossデータでも○としていないので、毒性値の取り扱いには注意が必要である。

　　　 　　　 　　　 　　　 　　　 　　　
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) Read-across * QSAR GLP 設定濃度 実測濃度 情報源 情報源による信頼性評価 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure duration value exposure duration unit toxicity value toxicity unit Read-across QSAR GLPnominal concentration measured concentrationoriginal work type original work reliability rankauthor title referenced journal publication year Information update date
藻類 Pseudokirchneriella subcapitata Population EC10 3 days 31000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
藻類 Pseudokirchneriella subcapitata Population EC50 3 days 15000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
藻類 Pseudokirchneriella subcapitata Population EC50 3 days 91000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
藻類 Pseudokirchneriella subcapitata Population EC10 3 days 7000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
藻類 Pseudokirchneriella subcapitata Population LOEC 3 days 50000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
藻類 Pseudokirchneriella subcapitata Population LOEC 3 days 10000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
藻類 Pseudokirchneriella subcapitata Population NOEC 3 days 20000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
藻類 Pseudokirchneriella subcapitata Population NOEC 3 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
藻類 Pseudokirchneriella subcapitata growth rate EC50 72 hours 91 mg/L 12 ECHA Information on Registered Substances 2 Madsen, T. , Boyd, H. B. , Nylen, D. , Pedersen, A. R. , Pedersen, G. I. , Simonsen, F. Environmental and health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Danish Environmental Protection Agency, Environmental project No. 615 2001, Miljoprojekt. CETOX (Centre for Integrated Environment and Toxicology). 2001 2017/02/19
藻類 Pseudokirchneriella subcapitata EC50 72 hours 30 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成28年3月版） 2016 2016/11/08
藻類 Pseudokirchneriella subcapitata EC50 72 hours 56 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成28年3月版） 2016 2016/11/08
藻類 Pseudokirchneriella subcapitata growth rate NOEC 72 hours 20 mg/L 12 ECHA Information on Registered Substances 2 Madsen, T. , Boyd, H. B. , Nylen, D. , Pedersen, A. R. , Pedersen, G. I. , Simonsen, F. Environmental and health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Danish Environmental Protection Agency, Environmental project No. 615 2001, Miljoprojekt. CETOX (Centre for Integrated Environment and Toxicology). 2001 2017/02/19
藻類 Pseudokirchneriella subcapitata growth rate LOEC 72 hours 50 mg/L 12 ECHA Information on Registered Substances 2 Madsen, T. , Boyd, H. B. , Nylen, D. , Pedersen, A. R. , Pedersen, G. I. , Simonsen, F. Environmental and health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Danish Environmental Protection Agency, Environmental project No. 615 2001, Miljoprojekt. CETOX (Centre for Integrated Environment and Toxicology). 2001 2017/02/19
藻類 Pseudokirchneriella subcapitata growth rate EC10 72 hours 31 mg/L 12 ECHA Information on Registered Substances 2 Madsen, T. , Boyd, H. B. , Nylen, D. , Pedersen, A. R. , Pedersen, G. I. , Simonsen, F. Environmental and health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Danish Environmental Protection Agency, Environmental project No. 615 2001, Miljoprojekt. CETOX (Centre for Integrated Environment and Toxicology). 2001 2017/02/19
藻類 Pseudokirchneriella subcapitata NOEC 72 hours 17 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成28年3月版） 2016 2016/11/08
藻類 Pseudokirchneriella subcapitata NOEC 72 hours 17 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成28年3月版） 2016 2016/11/08
甲殻類 Daphnia magna Physiology EC50 2 days 41100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kamaya,Y., Y. Fukaya, and K. Suzuki Acute Toxicity of Benzoic Acids to the Crustacean Daphnia magna Chemosphere59(2): 255-261 2005 2017/03/15
甲殻類 Daphnia magna Physiology EC10 2 days 4500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
甲殻類 Daphnia magna Physiology EC10 1 days 6240 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
甲殻類 Daphnia magna Physiology EC50 1 days 11400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
甲殻類 Daphnia magna Physiology EC50 2 days 11200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
甲殻類 Daphnia magna Physiology LOEC 2 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
甲殻類 Daphnia magna Physiology NOEC 2 days 2000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
甲殻類 Daphnia magna Physiology EC50 1 days 70000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kamaya,Y., Y. Fukaya, and K. Suzuki Acute Toxicity of Benzoic Acids to the Crustacean Daphnia magna Chemosphere59(2): 255-261 2005 2017/03/15
甲殻類 Daphnia magna mobility EC50 48 hours 11.2 mg/L 12 ECHA Information on Registered Substances 2 publication 2001 2017/02/19
甲殻類 Daphnia magna mobility EC50 24 hours 22.4 mg/L 12 ECHA Information on Registered Substances 2 publication 2001 2017/02/19
甲殻類 Ceriodaphnia sp. EC50 48 hours 36 mg/L ○ 12 ECHA Information on Registered Substances 4 publication 1999 2017/02/07
甲殻類 Daphnia magna mobility EC50 48 hours 41.1 mg/L 12 ECHA Information on Registered Substances 2 Kamaya, Y. , Fukaya, Y. , Suzuki, K. Acute toxicity of benzoic acids to the crustacean Daphnia magna Chemosphere 2005 2017/02/07
甲殻類 Daphnia magna mobility EC50 24 hours 70 mg/L 12 ECHA Information on Registered Substances 2 Kamaya, Y. , Fukaya, Y. , Suzuki, K. Acute toxicity of benzoic acids to the crustacean Daphnia magna Chemosphere 2005 2017/02/07
甲殻類 Daphnia magna mobility EC10 48 hours 4.5 mg/L 12 ECHA Information on Registered Substances 2 publication 2001 2017/02/19
甲殻類 Daphnia magna mobility EC10 24 hours 6.24 mg/L 12 ECHA Information on Registered Substances 2 publication 2001 2017/02/19
甲殻類 Daphnia magna EC50 48 hours 36 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成28年3月版） 2016 2016/11/08
甲殻類 Daphnia magna reproduction 21 days 0.8 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2000 2017/02/07
甲殻類 Daphnia magna mortality EC50 21 days 0.89 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2000 2017/02/07
甲殻類 Daphnia magna reproduction NOEC 21 days 0.2 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2000 2017/02/07
甲殻類 Daphnia magna reproduction EC50 21 days 5.32 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2000 2017/02/07
甲殻類 Daphnia magna EC50 21 days 5.3 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成28年3月版） 2016 2016/11/08
甲殻類 Daphnia magna NOEC 21 days 0.2 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成28年3月版） 2016 2016/11/08
魚類 Danio rerio (Zebrafish) Growth EC10 2 days 19800 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Schiller,V., A. Wichmann, R. Kriehuber, C. Schafers, R. Fischer, and M. Fenske Transcriptome Alterations in Zebrafish Embryos After Exposure to Environmental Estrogens and Anti-Androgens can Reveal Endocrine Disruption Reprod. Toxicol.42:210-223 2013 2017/03/15
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 2 days 24400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Schiller,V., A. Wichmann, R. Kriehuber, C. Schafers, R. Fischer, and M. Fenske Transcriptome Alterations in Zebrafish Embryos After Exposure to Environmental Estrogens and Anti-Androgens can Reveal Endocrine Disruption Reprod. Toxicol.42:210-223 2013 2017/03/15
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 2 days 24400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Schiller,V., A. Wichmann, R. Kriehuber, C. Schafers, R. Fischer, and M. Fenske Transcriptome Alterations in Zebrafish Embryos After Exposure to Environmental Estrogens and Anti-Androgens can Reveal Endocrine Disruption Reprod. Toxicol.42:210-223 2013 2017/03/15
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 2 days 24400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Schiller,V., A. Wichmann, R. Kriehuber, C. Schafers, R. Fischer, and M. Fenske Transcriptome Alterations in Zebrafish Embryos After Exposure to Environmental Estrogens and Anti-Androgens can Reveal Endocrine Disruption Reprod. Toxicol.42:210-223 2013 2017/03/15
魚類 Oryzias latipes (Japanese medaka) mortality LC50 48 hours 79.5 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2000 2017/02/02
魚類 Oryzias latipes (Japanese medaka) mortality LC50 24 hours >100 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2000 2017/02/02
魚類 Oryzias latipes (Japanese medaka) mortality LC50 72 hours 70.6 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2000 2017/02/02
魚類 Oryzias latipes (Japanese medaka) mortality LC50 96 hours 59.5 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2000 2017/02/02
魚類 Oryzias latipes (Japanese medaka) LC50 96 hours 60 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成28年3月版） 2016 2016/11/08
魚類 Leuciscus idus (Orfe) NOEC 48 hours 50 mg/L 12 ECHA Information on Registered Substances 4 Madsen, T. , Boyd, H. B. , Nylen, D. , Pedersen, A. R. , Pedersen, G. I. , Simonsen, F. Environmental and health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Danish Environmental Protection Agency, Environmental project No. 615 2001, Miljoprojekt. CETOX (Centre for Integrated Environment and Toxicology). 2001 2017/02/07