生態影響に係る有害性情報


CAS登録番号 CAS RN ® : 100-00-5
官報公示整理番号 METI No. : 3-442
物質名 test material : p-ニトロクロロベンゼン /p-Nitrochlorobenzene
水溶解度 water solubility : 225mg/L (推計値 estimated)
LogKow : 2.39 (実測値 measured)
備考 remarks
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書) / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし 4:情報が少なく評価不能
日本環境省 化学物質の環境リスク評価(生態リスク初期評価) A:試験は信頼できる B:試験は条件付きで信頼できる C:試験の信頼性は低い D:信頼性の判定不可 E:信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり Supplemental:条件付きで信頼性あり Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり:○
なし:×
情報源 情報源による
信頼性評価**
著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value
exposure
duration
unit
toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material
original work type original work
reliability rank
author title referenced journal publication year Information
update date
藻類 Scenedesmus subspicatus Population NOEC >=250000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Nendza,M., and A. Wenzel Discriminating Toxicant Classes by Mode of Action 1. (Eco)toxicity Profiles Environ. Sci. Pollut. Res.13(3): 192-203 2006 2016/03/25
藻類 Scenedesmus subspicatus Population EC50 2 days 8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., and M. Pattard Results of the Harmful Effects of Water Pollutants to Green Algae (Scenedesmus subspicatus) in the Cell Multiplication Inhibition Test Water Res.24(1): 31-38 1990 2016/03/25
藻類 Scenedesmus subspicatus Population EC50 2 days 16000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., and M. Pattard Results of the Harmful Effects of Water Pollutants to Green Algae (Scenedesmus subspicatus) in the Cell Multiplication Inhibition Test Water Res.24(1): 31-38 1990 2016/03/25
藻類 Scenedesmus subspicatus Cellular Effects EC3 7 days 10000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Trenel,J., and R. Kuhn Bewertung Wassergefahrdender Stoffe im Hinblick auf Lagerung, Umschlag und Transport Umweltforschungsplan des Bundesministers des Innern: 1982 2016/03/25
甲殻類 Daphnia magna Behavior EC50 6000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Knie,J., A. Halke, I. Juhnke, and W. Schiller Results of Studies on Chemical Substances with Four Biotests (Ergebnisse der Untersuch-Ungen von Chemischen Stoffen mit vier Biotests) Dtsch. Gewaesserkd. Mitt.27(3): 77-79 1983 2016/03/25
甲殻類 Daphnia magna Mortality LC50 2 days 8900 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Canton,J.H., W. Slooff, H.J. Kool, J. Struys, Th.J.M. Pouw, R.C.C. Wegman, and G.J. Piet Toxicity, Biodegradability, and Accumulation of a Number of Cl/N-Containing Compounds for Classification and Establishing Water Quality Criteria Regul. Toxicol. Pharmacol.5:123-131 1985 2016/03/25
甲殻類 Daphnia magna Behavior EC50 1 days 15000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R. Schadstoffwirkungen von Umweltchemikalien im Daphnien-Reproduktions-Test als Grundlage fr die Bewertung der Umweltgefhrlichkeit in Aquatischen Sys Forschungsbericht 10603052, Mrz: 1988 2016/03/25
甲殻類 Daphnia magna Behavior EC50 1 days 13000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Trenel,J., and R. Kuhn Bewertung Wassergefahrdender Stoffe im Hinblick auf Lagerung, Umschlag und Transport Umweltforschungsplan des Bundesministers des Innern: 1982 2016/03/25
甲殻類 Daphnia magna Physiology EC50 1 days 15000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., M. Pattard, K.D. Pernak, and A. Winter Results of the Harmful Effects of Water Pollutants to Daphnia magna in the 21 Day Reproduction Test Water Res.23(4): 501-510 1989 2016/03/25
甲殻類 Daphnia magna Behavior EC0 1 days 3300 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R. Schadstoffwirkungen von Umweltchemikalien im Daphnien-Reproduktions-Test als Grundlage fr die Bewertung der Umweltgefhrlichkeit in Aquatischen Sys Forschungsbericht 10603052, Mrz: 1988 2016/03/25
甲殻類 Daphnia magna Behavior NOEC 21 days 320 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R. Schadstoffwirkungen von Umweltchemikalien im Daphnien-Reproduktions-Test als Grundlage fr die Bewertung der Umweltgefhrlichkeit in Aquatischen Sys Forschungsbericht 10603052, Mrz: 1988 2016/03/25
甲殻類 Daphnia magna Reproduction NOEC 21 days 190 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., M. Pattard, K.D. Pernak, and A. Winter Results of the Harmful Effects of Water Pollutants to Daphnia magna in the 21 Day Reproduction Test Water Res.23(4): 501-510 1989 2016/03/25
甲殻類 Daphnia magna Mortality 21 days 3200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Maas-Diepeveen,J.L., and C.J. Van Leeuwen Aquatic Toxicity of Aromatic Nitro Compounds and Anilines to Several Freshwater Species Report No.86-42, Laboratory for Ecotoxicology, Institute for Inland Water Management and Waste Water Treatment:10 p. 1986 2016/03/25
甲殻類 Daphnia magna Physiology EC50 2 days 2700 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Canton,J.H., W. Slooff, H.J. Kool, J. Struys, Th.J.M. Pouw, R.C.C. Wegman, and G.J. Piet Toxicity, Biodegradability, and Accumulation of a Number of Cl/N-Containing Compounds for Classification and Establishing Water Quality Criteria Regul. Toxicol. Pharmacol.5:123-131 1985 2016/03/25
甲殻類 Daphnia magna Mortality LC50 21 days 4600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Maas-Diepeveen,J.L., and C.J. Van Leeuwen Aquatic Toxicity of Aromatic Nitro Compounds and Anilines to Several Freshwater Species Report No.86-42, Laboratory for Ecotoxicology, Institute for Inland Water Management and Waste Water Treatment:10 p. 1986 2016/03/25
甲殻類 Daphnia magna Mortality LC50 2 days 6700 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Maas-Diepeveen,J.L., and C.J. Van Leeuwen Aquatic Toxicity of Aromatic Nitro Compounds and Anilines to Several Freshwater Species Report No.86-42, Laboratory for Ecotoxicology, Institute for Inland Water Management and Waste Water Treatment:10 p. 1986 2016/03/25
甲殻類 Daphnia magna Reproduction 21 days 1800 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Maas-Diepeveen,J.L., and C.J. Van Leeuwen Aquatic Toxicity of Aromatic Nitro Compounds and Anilines to Several Freshwater Species Report No.86-42, Laboratory for Ecotoxicology, Institute for Inland Water Management and Waste Water Treatment:10 p. 1986 2016/03/25
甲殻類 Daphnia magna Intoxication IC50 24 hours 16.5 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Zhao, Y.H., Ji G.D., Cronin M.T.D., Dearden J.C. QSAR of chemicals acting by non-polar narcosis-Theoretical considerations. 1998 2016/02/08
甲殻類 Daphnia magna Mortality LC50 48 hours 7.72 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Peter C. von der Ohe, Ralph Kühne, Ralf-Uwe Ebert, Rolf Altenburger, Matthias Liess, and Gerrit Schüürmann Structural Alerts-A New Classification Model to Discriminate Excess Toxicity from Narcotic Effect Levels of Organic Compounds in the Acute Daphnid Assay 2005 2016/02/08
甲殻類 Daphnia magna Intoxication ET50 24 hours 2.08 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Urrestarazu Ramos, E. Aquatic toxicity of polar narcotic pollutants/ Mechanism, modeling and environmental effect assessment (PhD Thesis) 1998 2016/02/08
甲殻類 Daphnia magna Reproduction LOEC 504 hours 0.38 mg/L 9 ECETOC Aquatic Toxicity, EAT Kühn ea 89 2016/02/08
甲殻類 Daphnia magna Reproduction NOEC 504 hours 0.19 mg/L 9 ECETOC Aquatic Toxicity, EAT Kühn ea 89 2023/11/21
魚類 Danio rerio (Zebrafish) Behavior NOEC 14 days 1530 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Roderer,G. Testung Wassergefahrdender Stoffe als Grundlage fur Wasserqualitatsstandards. Testbericht: Wassergefahrdende Stoffe Fraunhofer-Institut fur Umweltchemie und Okotoxikologie, Schmallenberg: 1990 2016/03/25
魚類 Cyprinus carpio (Carp) Mortality 4.96 days 165~236 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Loeb,H.A., and W.H. Kelly Acute Oral Toxicity of 1,496 Chemicals Force-Fed to Carp U.S.Fish.Wildl.Serv., Sp.Sci.Rep.-Fish.No.471, Washington, D.C.:124 p. 1963 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC0 2 days 8300 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Lysak,A., and J. Marcinek Multiple Toxic Effect of Simultaneous Action of Some Chemical Substances on Fish Rocz. Nauk Roln. Ser. H Rybactwo.94(3): 53-63 1972 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 4 days 15000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Roderer,G. Testung Wassergefahrdender Stoffe als Grundlage fur Wasserqualitatsstandards. Testbericht: Wassergefahrdende Stoffe Fraunhofer-Institut fur Umweltchemie und Okotoxikologie, Schmallenberg: 1990 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 2 days 15000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Roderer,G. Testung Wassergefahrdender Stoffe als Grundlage fur Wasserqualitatsstandards. Testbericht: Wassergefahrdende Stoffe Fraunhofer-Institut fur Umweltchemie und Okotoxikologie, Schmallenberg: 1990 2016/03/25
魚類 Leuciscus idus (Orfe) Mortality LC50 2000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Knie,J., A. Halke, I. Juhnke, and W. Schiller Results of Studies on Chemical Substances with Four Biotests (Ergebnisse der Untersuch-Ungen von Chemischen Stoffen mit vier Biotests) Dtsch. Gewaesserkd. Mitt.27(3): 77-79 1983 2016/03/25
魚類 Poecilia reticulata (Guppy) Mortality LC50 14 days 6600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Maas-Diepeveen,J.L., and C.J. Van Leeuwen Aquatic Toxicity of Aromatic Nitro Compounds and Anilines to Several Freshwater Species Report No.86-42, Laboratory for Ecotoxicology, Institute for Inland Water Management and Waste Water Treatment:10 p. 1986 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 7 days 45000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Maas-Diepeveen,J.L., and C.J. Van Leeuwen Aquatic Toxicity of Aromatic Nitro Compounds and Anilines to Several Freshwater Species Report No.86-42, Laboratory for Ecotoxicology, Institute for Inland Water Management and Waste Water Treatment:10 p. 1986 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC100 2 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Lysak,A., and J. Marcinek Multiple Toxic Effect of Simultaneous Action of Some Chemical Substances on Fish Rocz. Nauk Roln. Ser. H Rybactwo.94(3): 53-63 1972 2016/03/25
魚類 Danio rerio (Zebrafish) Reproduction EC50 7 days 14000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Maas-Diepeveen,J.L., and C.J. Van Leeuwen Aquatic Toxicity of Aromatic Nitro Compounds and Anilines to Several Freshwater Species Report No.86-42, Laboratory for Ecotoxicology, Institute for Inland Water Management and Waste Water Treatment:10 p. 1986 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 48 hours 14.4 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) - Biodegradation and Bioaccumulation Data of Existing Chemicals Based on the CSCL Japan 1992 2016/02/08
魚類 Poecilia reticulata (Guppy) Mortality LC50 96 hours 5.99 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Raevsky, O.A., and Dearden, J.C. Creation of predictive models of aquatic toxicity of environmental pollutants with different mechanisms of action on the basis of molecular similarity and hybot descriptors. 2004 2016/02/08