【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。
生物種 | 学名 | 影響内容 | エンドポイント | 暴露期間(値) | 暴露期間(単位) | 毒性値 | 毒性値(単位) | 毒性値(単位)種別 | 試験中の 被験物質 濃度測定 あり:○ なし:× |
情報源 | 情報源による 信頼性評価** |
著者 | タイトル | 記載誌 | 発行年 | 情報更新日 | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
subject type | scientific name | effect | endpoint | exposure duration value |
exposure duration unit |
toxicity value | toxicity unit | toxicity unit type | Read-across* | QSAR | GLP | measurement of the test material |
original work type | original work reliability rank |
author | title | referenced journal | publication year | Information update date |
藻類 | Chlorella vulgaris | Population | 7 | days | 5000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Hutchinson,T.C. | Comparative Studies of the Toxicity of Heavy Metals to Phytoplankton and Their Synergistic Interactions | Water Pollut. Res. Can.8:68-90 | 1973 | 2016/03/25 | |||||||
藻類 | Pseudokirchneriella subcapitata | growth rate | EC50 | 72 | hours | >30.1 | mg/L | element, total Ba | ○ | 12 ECHA Information on Registered Substances | 2 | study report | 2010 | 2017/03/10 | |||||
藻類 | Pseudokirchneriella subcapitata | growth rate | EC50 | 72 | hours | >1.15 | mg/L | dissolved, Ba | ○ | 12 ECHA Information on Registered Substances | 2 | study report | 2010 | 2017/03/10 | |||||
藻類 | Pseudokirchneriella subcapitata | growth rate | EC50 | 72 | hours | >85.3 | mg/L | barium dichloride | ○ | 12 ECHA Information on Registered Substances | 2 | study report | 2010 | 2017/03/10 | |||||
藻類 | Pseudokirchneriella subcapitata | growth rate | EC50 | 72 | hours | >100 | mg/L | ○ | 12 ECHA Information on Registered Substances | 2 | study report | 2010 | 2017/03/10 | ||||||
藻類 | Pseudokirchneriella subcapitata | growth rate | EC50 | 72 | hours | >85.3 | mg/L | nominal barium dichloride | ○ | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | study report | 2010 | 2022/09/15 | |||
藻類 | Chlorella sp. | growth rate | EC50 | 48 | hours | >=200~<=280 | mg/L | meas. (arithm. mean) test mat. (dissolved fraction) | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | publication | 2018 | 2022/09/15 | ||||
藻類 | Pseudokirchneriella subcapitata | growth rate | EC50 | 72 | hours | >30.1 | mg/L | meas. (geom. mean) element | ○ | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | study report | 2010 | 2022/09/15 | |||
藻類 | Pseudokirchneriella subcapitata | growth rate | EC50 | 72 | hours | >100 | mg/L | nominal test mat. | ○ | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | study report | 2010 | 2022/09/15 | |||
藻類 | Pseudokirchneriella subcapitata | growth rate | EC50 | 72 | hours | >1.15 | mg/L | meas. (geom. mean) dissolved | ○ | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | study report | 2010 | 2022/09/15 | |||
藻類 | Pseudokirchneriella subcapitata | growth rate | NOEC | 72 | hours | >=1.15 | mg/L | dissolved, Ba | ○ | 12 ECHA Information on Registered Substances | 2 | study report | 2010 | 2017/03/10 | |||||
藻類 | Pseudokirchneriella subcapitata | growth rate | NOEC | 72 | hours | >=100 | mg/L | ○ | 12 ECHA Information on Registered Substances | 2 | study report | 2010 | 2017/03/10 | ||||||
藻類 | Pseudokirchneriella subcapitata | growth rate | NOEC | 72 | hours | >=30.1 | mg/L | element, total Ba | ○ | 12 ECHA Information on Registered Substances | 2 | study report | 2010 | 2017/03/10 | |||||
藻類 | Pseudokirchneriella subcapitata | growth rate | NOEC | 72 | hours | >=85.3 | mg/L | barium dichloride | ○ | 12 ECHA Information on Registered Substances | 2 | study report | 2010 | 2017/03/10 | |||||
藻類 | Chlorella sp. | growth rate | EC10 | 48 | hours | >=27~<=54 | mg/L | meas. (arithm. mean) test mat. (dissolved fraction) | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | publication | 2018 | 2022/09/15 | ||||
藻類 | Pseudokirchneriella subcapitata | growth rate | NOEC | 72 | hours | >=30.1 | mg/L | meas. (geom. mean) element | ○ | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | study report | 2010 | 2022/09/15 | |||
藻類 | Pseudokirchneriella subcapitata | growth rate | NOEC | 72 | hours | >=100 | mg/L | nominal test mat. | ○ | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | study report | 2010 | 2022/09/15 | |||
藻類 | Pseudokirchneriella subcapitata | growth rate | NOEC | 72 | hours | >=1.15 | mg/L | meas. (geom. mean) dissolved | ○ | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | study report | 2010 | 2022/09/15 | |||
藻類 | Pseudokirchneriella subcapitata | growth rate | NOEC | 72 | hours | >=85.3 | mg/L | nominal barium dichloride | ○ | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | study report | 2010 | 2022/09/15 | |||
甲殻類 | Daphnia magna | Physiology | EC50 | 1 | days | 801 | μmol/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Calleja,M.C., G. Persoone, and P. Geladi | Comparative Acute Toxicity of the First 50 Multicentre Evaluation of In Vitro Cytotoxicity Chemicals to Aquatic Non-vertebrates | Arch. Environ. Contam. Toxicol.26(1): 69-78 | 1994 | 2017/03/15 | ||||||
甲殻類 | Daphnia magna | Physiology | EC50 | 1 | days | 0.512 | mM | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Lilius,H., B. Isomaa, and T. Holmstrom | A Comparison of the Toxicity of 50 Reference Chemicals to Freshly Isolated Rainbow Trout Hepatocytes and Daphnia magna | Aquat. Toxicol.30:47-60 | 1994 | 2017/03/15 | ||||||
甲殻類 | Daphnia magna | Physiology | EC50 | 1 | days | 0.512 | mM | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Lilius,H., B. Isomaa, and T. Holmstrom | A Comparison of the Toxicity of 50 Reference Chemicals to Freshly Isolated Rainbow Trout Hepatocytes and Daphnia magna | Aquat. Toxicol.30:47-60 | 1994 | 2016/03/25 | ||||||
甲殻類 | Daphnia magna | Physiology | EC50 | 1 | days | 801 | μmol/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Calleja,M.C., G. Persoone, and P. Geladi | Comparative Acute Toxicity of the First 50 Multicentre Evaluation of In Vitro Cytotoxicity Chemicals to Aquatic Non-vertebrates | Arch. Environ. Contam. Toxicol.26(1): 69-78 | 1994 | 2016/03/25 | ||||||
甲殻類 | Daphnia magna | Intoxication/Immobile | EC50 | 24 | hours | 0.512 | mM | Total | × | 16 ECOTOX | Lilius,H., B. Isomaa, and T. Holmstrom | A Comparison of the Toxicity of 50 Reference Chemicals to Freshly Isolated Rainbow Trout Hepatocytes and Daphnia magna | Aquat. Toxicol.30 | 1994 | 2022/09/15 | ||||
甲殻類 | Daphnia magna | mobility | EC50 | 24 | hours | 133.8 | mg/L | 12 ECHA Information on Registered Substances | 3 | Lilius H, Isomaa B, Holmström T | A comparison of the toxicity of 50 reference chemicals to freshly isolated rainbow trout hepatocytes and Daphnia magna | Aquatic Toxicology | 1994 | 2017/03/09 | |||||
甲殻類 | Daphnia magna | mobility | EC50 | 24 | hours | 110 | mg/L | element, total Ba | 12 ECHA Information on Registered Substances | 3 | Calleja MC, Persoone G, Geladi P | Comparative Acute Toxicity of the First 50 Multicentre Evaluation of In Vitro Cytotoxicity Chemicals to Aquatic Non-Vertebrates | Archives of Environmental Contamination and Toxicology | 1993 | 2017/03/10 | ||||
甲殻類 | Daphnia magna | mobility | EC50 | 24 | hours | 70.31 | mg/L | element, total Ba | 12 ECHA Information on Registered Substances | 3 | Lilius H, Isomaa B, Holmström T | A comparison of the toxicity of 50 reference chemicals to freshly isolated rainbow trout hepatocytes and Daphnia magna | Aquatic Toxicology | 1994 | 2017/03/09 | ||||
甲殻類 | Daphnia magna | mortality including immobility | LC50 | 48 | hours | 14.5 | mg/L | element metal ion-based | 12 ECHA Information on Registered Substances | 2 | Biesinger KE, Christensen GM | Effects of various metals on survival, growth, reproduction, and metabolism of Daphnia magna | Journal of the Fisheries Research Board of Canada | 1972 | 2017/03/09 | ||||
甲殻類 | Daphnia magna | mobility | EC50 | 24 | hours | 209 | mg/L | 12 ECHA Information on Registered Substances | 3 | Calleja MC, Persoone G, Geladi P | Comparative Acute Toxicity of the First 50 Multicentre Evaluation of In Vitro Cytotoxicity Chemicals to Aquatic Non-Vertebrates | Archives of Environmental Contamination and Toxicology | 1993 | 2017/03/10 | |||||
甲殻類 | Daphnia magna | mortality including immobility | LC50 | 48 | hours | 14.5 | mg/L | nominal element | ○ | × | 12 ECHA Information on Registered Substances | 2 | Biesinger KE, Christensen GM | Effects of various metals on survival, growth, reproduction, and metabolism of Daphnia magna | Journal of the Fisheries Research Board of Canada 29: 1691-1700 | 1972 | 2022/09/15 | ||
甲殻類 | Ceriodaphnia dubia | mobility | EC50 | 48 | hours | >=16~<=18 | mg/L | meas. (arithm. mean) test mat. (dissolved fraction) | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | publication | 2018 | 2022/09/15 | ||||
甲殻類 | Daphnia magna | Intoxication/Immobile | EC50 | 24 | hours | 801 | µmol/L | Total | × | 16 ECOTOX | Calleja,M.C., G. Persoone, and P. Geladi | Comparative Acute Toxicity of the First 50 Multicentre Evaluation of In Vitro Cytotoxicity Chemicals to Aquatic Non-vertebrates | Arch. Environ. Contam. Toxicol.26(1) | 1994 | 2022/09/15 | ||||
甲殻類 | Daphnia magna | mobility | EC50 | 24 | hours | 133.8 | mg/L | nominal test mat. | 12 ECHA Information on Registered Substances | 3 | Lilius H, Isomaa B, Holmström T | A comparison of the toxicity of 50 reference chemicals to freshly isolated rainbow trout hepatocytes and Daphnia magna | Aquatic Toxicology 30: 47-60 | 1994 | 2022/09/15 | ||||
甲殻類 | Daphnia magna | mobility | EC50 | 24 | hours | 209 | mg/L | nominal test mat. | × | 12 ECHA Information on Registered Substances | 3 | Calleja MC, Persoone G, Geladi P | Comparative Acute Toxicity of the First 50 Multicentre Evaluation of In Vitro Cytotoxicity Chemicals to Aquatic Non-Vertebrates | Archives of Environmental Contamination and Toxicology 26: 69-78 | 1993 | 2022/09/15 | |||
甲殻類 | Ceriodaphnia dubia | mobility | EC10 | 48 | hours | >=13~<=15 | mg/L | meas. (arithm. mean) test mat. (dissolved fraction) | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | publication | 2018 | 2022/09/15 | ||||
甲殻類 | Daphnia magna | mobility | EC50 | 24 | hours | 110 | mg/L | nominal element | × | 12 ECHA Information on Registered Substances | 3 | Calleja MC, Persoone G, Geladi P | Comparative Acute Toxicity of the First 50 Multicentre Evaluation of In Vitro Cytotoxicity Chemicals to Aquatic Non-Vertebrates | Archives of Environmental Contamination and Toxicology 26: 69-78 | 1993 | 2022/09/15 | |||
甲殻類 | Daphnia magna | mobility | EC50 | 24 | hours | 70.31 | mg/L | nominal element | 12 ECHA Information on Registered Substances | 3 | Lilius H, Isomaa B, Holmström T | A comparison of the toxicity of 50 reference chemicals to freshly isolated rainbow trout hepatocytes and Daphnia magna | Aquatic Toxicology 30: 47-60 | 1994 | 2022/09/15 | ||||
甲殻類 | Daphnia magna | reproduction | NOEC | 21 | days | 2.9 | mg/L | metal ion | 12 ECHA Information on Registered Substances | 2 | Biesinger KE, Christensen GM | Effects of various metals on survival, growth, reproduction, and metabolism of Daphnia magna | Journal of the Fisheries Research Board of Canada | 1972 | 2017/03/10 | ||||
甲殻類 | Daphnia magna | reproduction | NOEC | 21 | days | 2.9 | mg/L | nominal metal ion | ○ | × | 12 ECHA Information on Registered Substances | 2 | Biesinger KE, Christensen GM | Effects of various metals on survival, growth, reproduction, and metabolism of Daphnia magna | Journal of the Fisheries Research Board of Canada 29: 1691-1700 | 1972 | 2022/09/15 | ||
甲殻類 | Daphnia magna | reproduction | EC16 | 21 | days | 5.8 | mg/L | nominal metal-ion | ○ | × | 12 ECHA Information on Registered Substances | 2 | Biesinger KE, Christensen GM | Effects of various metals on survival, growth, reproduction, and metabolism of Daphnia magna | Journal of the Fisheries Research Board of Canada 29: 1691-1700 | 1972 | 2022/09/15 | ||
魚類 | Gasterosteus aculeatus (Three-spined stickleback) | Mortality | 10 | days | 400000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Jones,J.R.E. | The Relation Between the Electrolytic Solution Pressures of the Metals and Their Toxicity to the Stickleback (Gasterosteus aculeatus L.) | J. Exp. Biol.16(4): 425-437 | 1939 | 2017/03/15 | |||||||
魚類 | Gasterosteus aculeatus (Three-spined stickleback) | Mortality | 10 | days | 400000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Jones,J.R.E. | The Relation Between the Electrolytic Solution Pressures of the Metals and Their Toxicity to the Stickleback (Gasterosteus aculeatus L.) | J. Exp. Biol.16(4): 425-437 | 1939 | 2016/03/25 | |||||||
魚類 | Lepomis macrochirus (Bluegill) | No Group Code | 1 | days | 5000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Applegate,V.C., J.H. Howell, A.E.,Jr. Hall, and M.A. Smith | Toxicity of 4,346 Chemicals to Larval Lampreys and Fishes | Spec.Sci.Rep.Fish.No.207, Fish Wildl.Serv., U.S.D.I., Washington, DC:157 p. | 1957 | 2016/03/25 | |||||||
魚類 | Oncorhynchus mykiss (Rainbow trout) | No Group Code | 1 | days | 5000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Applegate,V.C., J.H. Howell, A.E.,Jr. Hall, and M.A. Smith | Toxicity of 4,346 Chemicals to Larval Lampreys and Fishes | Spec.Sci.Rep.Fish.No.207, Fish Wildl.Serv., U.S.D.I., Washington, DC:157 p. | 1957 | 2016/03/25 | |||||||
魚類 | Gasterosteus aculeatus | Mortality/Mortality | NR-LETH | 10 | days | 400000 | µg/L | Total | × | 16 ECOTOX | Jones,J.R.E. | The Relation Between the Electrolytic Solution Pressures of the Metals and Their Toxicity to the Stickleback (Gasterosteus aculeatus L.) | J. Exp. Biol.16(4) | 2022/09/15 | |||||
魚類 | Danio rerio (Zebrafish) | mortality | LC50 | 96 | hours | >97.5 | mg/L | element, total Ba | ○ | 12 ECHA Information on Registered Substances | 2 | study report | 2010 | 2017/02/23 | |||||
魚類 | Danio rerio (Zebrafish) | mortality | LC50 | 96 | hours | >3.5 | mg/L | dissolved | ○ | 12 ECHA Information on Registered Substances | 2 | study report | 2010 | 2017/02/23 | |||||
魚類 | Danio rerio (Zebrafish) | mortality | LC50 | 96 | hours | >174 | mg/L | ○ | 12 ECHA Information on Registered Substances | 2 | study report | 2010 | 2017/02/23 | ||||||
魚類 | Danio rerio | mortality (fish) | LC50 | 96 | hours | >97.5 | mg/L | meas. (geom. mean) element (total fraction) | ○ | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | study report | 2010 | 2022/09/15 | |||
魚類 | Danio rerio | mortality (fish) | LC50 | 96 | hours | >3.5 | mg/L | meas. (geom. mean) test mat. (dissolved fraction) | ○ | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | study report | 2010 | 2022/09/15 | |||
魚類 | Danio rerio | mortality (fish) | LC50 | 96 | hours | >174 | mg/L | meas. (geom. mean) test mat. | ○ | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | study report | 2010 | 2022/09/15 | |||
魚類 | Danio rerio (Zebrafish) | hatching success, mortality (post-hatch success), numbers of healthy fish, length of the surviving fish, dry weight of the surviving fish | NOEC | 33 | days | >=100 | mg/L | ○ | 12 ECHA Information on Registered Substances | 2 | study report | 2014 | 2017/03/09 | ||||||
魚類 | Danio rerio (Zebrafish) | LOEC | 33 | days | >1.26 | mg/L | dissolved, barium | ○ | 12 ECHA Information on Registered Substances | 2 | study report | 2014 | 2017/03/09 | ||||||
魚類 | Danio rerio (Zebrafish) | hatching success, mortality (post-hatch success), numbers of healthy fish, length of the surviving fish, dry weight of the surviving fish | NOEC | 33 | days | >=40.3 | mg/L | total barium | ○ | 12 ECHA Information on Registered Substances | 2 | study report | 2014 | 2017/03/09 | |||||
魚類 | Danio rerio (Zebrafish) | hatching success, mortality (post-hatch success), numbers of healthy fish, length of the surviving fish, dry weight of the surviving fish | LOEC | 33 | days | >40.3 | mg/L | total barium | ○ | 12 ECHA Information on Registered Substances | 2 | study report | 2014 | 2017/03/09 | |||||
魚類 | Danio rerio (Zebrafish) | hatching success, mortality (post-hatch success), numbers of healthy fish, length of the surviving fish, dry weight of the surviving fish | LOEC | 33 | days | >100 | mg/L | ○ | 12 ECHA Information on Registered Substances | 2 | study report | 2014 | 2017/03/09 | ||||||
魚類 | Danio rerio (Zebrafish) | NOEC | 33 | days | >=1.26 | mg/L | dissolved, barium | ○ | 12 ECHA Information on Registered Substances | 2 | study report | 2014 | 2017/03/09 | ||||||
魚類 | Danio rerio | hatching success, mortality (post-hatch suc | NOEC | 33 | days | >=40.3 | mg/L | meas. (geom. mean) element (total fraction) | ○ | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | study report | 2014 | 2022/09/15 | |||
魚類 | Danio rerio | hatching success, mortality (post-hatch suc | LOEC | 33 | days | >1.26 | mg/L | meas. (geom. mean) dissolved | ○ | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | study report | 2014 | 2022/09/15 | |||
魚類 | Danio rerio | hatching success, mortality (post-hatch suc | LOEC | 33 | days | >100 | mg/L | nominal test mat. | ○ | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | study report | 2014 | 2022/09/15 | |||
魚類 | Danio rerio | hatching success, mortality (post-hatch suc | NOEC | 33 | days | >=1.26 | mg/L | meas. (geom. mean) element (dissolved fraction) | ○ | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | study report | 2014 | 2022/09/15 | |||
魚類 | Danio rerio | hatching success, mortality (post-hatch suc | NOEC | 33 | days | >=100 | mg/L | nominal test mat. | ○ | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | study report | 2014 | 2022/09/15 | |||
魚類 | Danio rerio | hatching success, mortality (post-hatch suc | LOEC | 33 | days | >40.3 | mg/L | meas. (geom. mean) element (total fraction) | ○ | ○ | ○ | 12 ECHA Information on Registered Substances | 1 | study report | 2014 | 2022/09/15 |