生態影響に係る有害性情報


CAS登録番号 CAS RN ® ： 101-84-8
官報公示整理番号　METI No. ： 3-650
物質名 test material ： フェノキシベンゼン　／Phenoxybenzene
水溶解度 water solubility ： 18mg/L (推計値 estimated)
LogKow ： 4.21 (実測値 measured)
備考 remarks ：
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書） / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし　4:情報が少なく評価不能
日本環境省　化学物質の環境リスク評価（生態リスク初期評価） A：試験は信頼できる　B：試験は条件付きで信頼できる　C：試験の信頼性は低い　D：信頼性の判定不可　E：信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり　Supplemental:条件付きで信頼性あり　Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり：○
なし：×		 情報源 情報源による
信頼性評価**		 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value		 exposure
duration
unit		 toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material		 original work type original work
reliability rank		 author title referenced journal publication year Information
update date
藻類 Pseudokirchneriella subcapitata Population EC50 4 days 1700 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) U.S. Environmental Protection Agency In-Depth Studies on Health and Environmental Impacts of Selected Water Pollutants U.S.EPA Contract No.68-01-4646, Duluth, MN:9 p. 1978 2016/03/25
藻類 Pseudokirchneriella subcapitata growth rate EC50 72 hours 0.58 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2005 2016/03/23
藻類 Pseudokirchneriella subcapitata decrease in chlorophyll a EC50 48 hours >2.5～5 × 12 ECHA Information on Registered Substances 2 study report 1980 2016/03/22
藻類 Pseudokirchneriella subcapitata biomass EC50 72 hours 0.405 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2005 2016/03/23
藻類 Pseudokirchneriella subcapitata growth rate EC50 72 hours 0.455 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2005 2016/03/23
藻類 Pseudokirchneriella subcapitata decrease in chlorophyll a EC50 24 hours >10 mg/L × 12 ECHA Information on Registered Substances 2 study report 1980 2016/03/22
藻類 Pseudokirchneriella subcapitata cell number EC50 96 hours 2.5 mg/L × 12 ECHA Information on Registered Substances 2 study report 1980 2016/03/22
藻類 Pseudokirchneriella subcapitata decrease in chlorophyll a EC50 96 hours 2.5 mg/L × 12 ECHA Information on Registered Substances 2 study report 1980 2016/03/22
藻類 Pseudokirchneriella subcapitata decrease in chlorophyll a EC50 72 hours >2.5～5 × 12 ECHA Information on Registered Substances 2 study report 1980 2016/03/22
藻類 Pseudokirchneriella subcapitata biomass EC50 72 hours 0.304 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2005 2016/03/23
藻類 Pseudokirchneriella subcapitata EC50 72 hours 0.41 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版） 2016/11/09
藻類 Pseudokirchneriella subcapitata EC50 72 hours 0.58 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版） 2016/11/09
藻類 Pseudokirchneriella subcapitata biomass NOEC 72 hours 0.188 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2005 2016/03/23
藻類 Pseudokirchneriella subcapitata biomass NOEC 72 hours 0.25 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2005 2016/03/23
藻類 Pseudokirchneriella subcapitata growth rate NOEC 72 hours 0.24 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2005 2016/03/23
藻類 Pseudokirchneriella subcapitata growth rate NOEC 72 hours 0.32 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2005 2016/03/23
藻類 Pseudokirchneriella subcapitata NOEC 72 hours 0.25 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版） 2016/11/09
藻類 Pseudokirchneriella subcapitata NOEC 72 hours 0.32 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版） 2016/11/09
甲殻類 Daphnia magna Mortality LC50 1 days 1400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) LeBlanc,G.A. Acute Toxicity of Priority Pollutants to Water Flea (Daphnia magna) Bull. Environ. Contam. Toxicol.24(5): 684-691 1980 2016/03/25
甲殻類 Daphnia magna Mortality LC50 2 days 670 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) LeBlanc,G.A. Acute Toxicity of Priority Pollutants to Water Flea (Daphnia magna) Bull. Environ. Contam. Toxicol.24(5): 684-691 1980 2016/03/25
甲殻類 Daphnia magna Mortality NOEC 2 days 410 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) LeBlanc,G.A. Acute Toxicity of Priority Pollutants to Water Flea (Daphnia magna) Bull. Environ. Contam. Toxicol.24(5): 684-691 1980 2016/03/25
甲殻類 Daphnia magna mobility EC50 24 hours 2.92 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2005 2016/03/23
甲殻類 Daphnia magna mobility EC100 48 hours 4.06 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2005 2016/03/23
甲殻類 Daphnia magna mortality LC50 24 hours 2.2 mg/L × 12 ECHA Information on Registered Substances 1 study report 1980 2016/03/23
甲殻類 Daphnia magna mobility EC50 48 hours 1.96 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2005 2016/03/23
甲殻類 Daphnia magna mortality LC50 48 hours 1.7 mg/L × 12 ECHA Information on Registered Substances 1 study report 1980 2016/03/23
甲殻類 Daphnia magna mobility EC100 24 hours >4.06 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2005 2016/03/23
甲殻類 Daphnia magna EC50 48 hours 2 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版） 2016/11/09
甲殻類 Daphnia magna Mortality LC50 48 hours 0.59 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Peter C. von der Ohe, Ralph Kühne, Ralf-Uwe Ebert, Rolf Altenburger, Matthias Liess, and Gerrit Schüürmann Structural Alerts-A New Classification Model to Discriminate Excess Toxicity from Narcotic Effect Levels of Organic Compounds in the Acute Daphnid Assay 2005 2016/02/08
甲殻類 Daphnia magna mobility 48 hours 0.76 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2005 2016/03/23
甲殻類 Daphnia magna mobility NOEC 24 hours 0.76 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2005 2016/03/23
甲殻類 Daphnia magna mortality NOEC 48 hours 1 mg/L × 12 ECHA Information on Registered Substances 1 study report 1980 2016/03/23
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 4 days 1700 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) U.S. Environmental Protection Agency In-Depth Studies on Health and Environmental Impacts of Selected Water Pollutants U.S.EPA Contract No.68-01-4646, Duluth, MN:9 p. 1978 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Accumulation 8 hours 29 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Wong,K., R.F. Addison, and F.C.P. Law Uptake, Metabolism, and Elimination of Diphenyl Ether by Trout and Stickleback Bull. Environ. Contam. Toxicol.26(2): 243-247 1981 2016/03/25
魚類 Cyprinus carpio (Carp) Mortality 2.75 days 77～198 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Loeb,H.A., and W.H. Kelly Acute Oral Toxicity of 1,496 Chemicals Force-Fed to Carp U.S.Fish.Wildl.Serv., Sp.Sci.Rep.-Fish.No.471, Washington, D.C.:124 p. 1963 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 4000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Geiger,D.L., D.J. Call, and L.T. Brooke Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales promelas) Volume IV Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI4:355 p. 1988 2016/03/25
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours 5.3 mg/L × 12 ECHA Information on Registered Substances 2 study report 1977 2016/03/23
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 13 mg/L × 12 ECHA Information on Registered Substances 2 study report 1980 2016/03/23
魚類 Pimephales promelas (Fathead minnow) mortality LC50 48 hours 13 mg/L × 12 ECHA Information on Registered Substances 2 study report 1980 2016/03/23
魚類 Pimephales promelas (Fathead minnow) mortality LC50 24 hours 34 mg/L × 12 ECHA Information on Registered Substances 2 study report 1980 2016/03/23
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 48 hours 6 mg/L × 12 ECHA Information on Registered Substances 2 study report 1980 2016/03/23
魚類 Pimephales promelas (Fathead minnow) mortality EC50 96 hours 2.5 mg/L × 12 ECHA Information on Registered Substances 2 study report 1977 2016/03/23
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 96 hours 4.2 mg/L × 12 ECHA Information on Registered Substances 2 study report 1980 2016/03/23
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 24 hours 10 mg/L × 12 ECHA Information on Registered Substances 2 study report 1980 2016/03/23
魚類 Pimephales promelas (Fathead minnow) Lethal EC50 96 hours 4 mg/L 9 ECETOC Aquatic Toxicity, EAT Veith ea 83 2016/02/08
魚類 Oryzias latipes (Japanese medaka) LC50 96 hours 1.8 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成27年3月版） 2016/11/09
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 48 hours 4.58 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) - Biodegradation and Bioaccumulation Data of Existing Chemicals Based on the CSCL Japan 1992 2016/02/08
魚類 Leuciscus idus (Orfe) Mortality LC50 96 hours 3.03 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Furusjö, E., Andersson, M., Rahmberg, M., Svenson, A. Estimating environmentally important properties of chemicals from the chemical structure 2003 2016/02/08
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 96 hours 3.99 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Russom, C.L., Bradbury, S.P., Broderius, S.J., Drummond, R.A. and Hammermeister, D.E. PREDICTING MODES OF TOXIC ACTION FROM CHEMICAL STRUCTURE: ACUTE TOXICITY IN THE FATHEAD MINNOW (PIMEPHALES PROMELAS) 1997 2016/02/08
魚類 Poecilia reticulata (Guppy) Mortality LC50 96 hours 4.08 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Raevsky, O.A., and Dearden, J.C. Creation of predictive models of aquatic toxicity of environmental pollutants with different mechanisms of action on the basis of molecular similarity and hybot descriptors. 2004 2016/02/08
魚類 Pimephales promelas (Fathead minnow) mortality and observations NOEC 96 hours 10 mg/L × 12 ECHA Information on Registered Substances 2 study report 1980 2016/03/23
魚類 Oncorhynchus mykiss (Rainbow trout) mortality NOEC 96 hours 3.2 mg/L × 12 ECHA Information on Registered Substances 2 study report 1980 2016/03/23