生態影響に係る有害性情報


CAS登録番号 CAS RN ® ： 106-89-8
官報公示整理番号　METI No. ： 2-275
物質名 test material ： ２－（クロロメチル）オキシラン　／2-(Chloromethyl)oxirane
水溶解度 water solubility ： 65900mg/L (推計値 estimated)
LogKow ： 0.45 (実測値 measured)
備考 remarks ：
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書） / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし　4:情報が少なく評価不能
日本環境省　化学物質の環境リスク評価（生態リスク初期評価） A：試験は信頼できる　B：試験は条件付きで信頼できる　C：試験の信頼性は低い　D：信頼性の判定不可　E：信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり　Supplemental:条件付きで信頼性あり　Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり：○
なし：×		 情報源 情報源による
信頼性評価**		 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value		 exposure
duration
unit		 toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material		 original work type original work
reliability rank		 author title referenced journal publication year Information
update date
甲殻類 Daphnia magna Mortality LC50 2 days 22600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Gersich,F.M., F.A. Blanchard, S.L. Applegath, and
C.N. Park		 The Precision of Daphnid (Daphnia magna Straus,
1820) Static Acute Toxicity Tests		 Arch. Environ. Contam. Toxicol.15(6): 741-749 1986 2016/03/25
甲殻類 Daphnia magna Mortality LC50 1 days 33400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Gersich,F.M., F.A. Blanchard, S.L. Applegath, and
C.N. Park		 The Precision of Daphnid (Daphnia magna Straus,
1820) Static Acute Toxicity Tests		 Arch. Environ. Contam. Toxicol.15(6): 741-749 1986 2016/03/25
甲殻類 Daphnia magna Mortality LC50 2 days 28900 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Gersich,F.M., F.A. Blanchard, S.L. Applegath, and
C.N. Park		 The Precision of Daphnid (Daphnia magna Straus,
1820) Static Acute Toxicity Tests		 Arch. Environ. Contam. Toxicol.15(6): 741-749 1986 2016/03/25
甲殻類 Daphnia magna Behavior EC100 1 days 53000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Bringmann,G., and R. Kuehn Results of Toxic Action of Water Pollutants on
Daphnia magna Straus Tested by an Improved
Standardized Procedure		 Z. Wasser-Abwasser-Forsch.15(1): 1-6 1982 2016/03/25
甲殻類 Daphnia magna Behavior EC50 1 days 40000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Bringmann,G., and R. Kuehn Results of Toxic Action of Water Pollutants on
Daphnia magna Straus Tested by an Improved
Standardized Procedure		 Z. Wasser-Abwasser-Forsch.15(1): 1-6 1982 2016/03/25
甲殻類 Daphnia magna Mortality LC50 2 days 21000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Gersich,F.M., F.A. Blanchard, S.L. Applegath, and
C.N. Park		 The Precision of Daphnid (Daphnia magna Straus,
1820) Static Acute Toxicity Tests		 Arch. Environ. Contam. Toxicol.15(6): 741-749 1986 2016/03/25
甲殻類 Daphnia magna Physiology LC100 1 days 44000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Bringmann,G., and R. Kuhn Results of the Damaging Effect of Water
Pollutants on Daphnia magna (Befunde der
Schadwirkung Wassergefahrdender
Stoffe Gegen Daphnia magna)		 TR-79-1204, Literature Research Company,
Annandale, VA:26 p.		 1977 2016/03/25
甲殻類 Daphnia magna Physiology LC0 1 days 20000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Bringmann,G., and R. Kuhn Results of the Damaging Effect of Water
Pollutants on Daphnia magna (Befunde der
Schadwirkung Wassergefahrdender
Stoffe Gegen Daphnia magna)		 TR-79-1204, Literature Research Company,
Annandale, VA:26 p.		 1977 2016/03/25
甲殻類 Daphnia magna Behavior EC0 1 days 30000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Bringmann,G., and R. Kuehn Results of Toxic Action of Water Pollutants on
Daphnia magna Straus Tested by an Improved
Standardized Procedure		 Z. Wasser-Abwasser-Forsch.15(1): 1-6 1982 2016/03/25
甲殻類 Daphnia magna Physiology LC50 1 days 30000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Bringmann,G., and R. Kuhn Results of the Damaging Effect of Water
Pollutants on Daphnia magna (Befunde der
Schadwirkung Wassergefahrdender
Stoffe Gegen Daphnia magna)		 TR-79-1204, Literature Research Company,
Annandale, VA:26 p.		 1977 2016/03/25
甲殻類 Daphnia magna Mortality LC50 2 days 23900 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Cowgill,U.M. Critical Analysis of Factors Affecting the
Sensitivity of Zooplankton and the
Reproducibility of Toxicity Test Results		 Water Res.21(12): 1453-1462 1987 2016/03/25
甲殻類 Daphnia magna Mortality LC50 48 hours 24.3 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Peter C. von der Ohe, Ralph Kühne, Ralf-Uwe Ebert,
Rolf Altenburger, Matthias Liess, and Gerrit
Schüürmann		 Structural Alerts-A New Classification Model to
Discriminate Excess Toxicity from Narcotic
Effect Levels of Organic Compounds in the
Acute Daphnid Assay		 2005 2016/02/08
甲殻類 Daphnia magna 遊泳阻害 EC50 48 hours 24 mg/L 18 既存化学物質安全性(ハザード)評価シート Richardson, M.L. et.al. The Dictionary of Substances and their Effects Royal Society of Chemistry 2016/03/03
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC100 2 days 38000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lysak,A., and J. Marcinek Multiple Toxic Effect of Simultaneous Action of
Some Chemical Substances on Fish		 Rocz. Nauk Roln. Ser. H Rybactwo.94(3): 53-63 1972 2016/03/25
魚類 Carassius auratus (Goldfish) Mortality LC50 1 days 23000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Bridie,A.L., C.J.M. Wolff, and M. Winter The Acute Toxicity of Some Petrochemicals to
Goldfish		 Water Res.13(7): 623-626 1979 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 12700 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mayes,M.A., H.C. Alexander, and D.C. Dill A Study to Assess the Influence of Age on the
Response of Fathead Minnows in Static Acute
Toxicity Tests		 Bull. Environ. Contam. Toxicol.31(2): 139-147 1983 2016/03/25
魚類 Carassius auratus (Goldfish) Mortality LC50 1 days 23000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Bridie,A.L., C.J.M. Wolff, and M. Winter The Acute Toxicity of Some Petrochemicals to
Goldfish		 Water Res.13(7): 623-626 1979 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 4 days 30500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wellens,H. Comparison of the Sensitivity of Brachydanio
rerio and Leuciscus idus by Testing the Fish
Toxicity of Chemicals and Wastewaters		 Z. Wasser-Abwasser-Forsch.51(2): 49-52 1982 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC0 2 days 19000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lysak,A., and J. Marcinek Multiple Toxic Effect of Simultaneous Action of
Some Chemical Substances on Fish		 Rocz. Nauk Roln. Ser. H Rybactwo.94(3): 53-63 1972 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 13200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mayes,M.A., H.C. Alexander, and D.C. Dill A Study to Assess the Influence of Age on the
Response of Fathead Minnows in Static Acute
Toxicity Tests		 Bull. Environ. Contam. Toxicol.31(2): 139-147 1983 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 10600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mayes,M.A., H.C. Alexander, and D.C. Dill A Study to Assess the Influence of Age on the
Response of Fathead Minnows in Static Acute
Toxicity Tests		 Bull. Environ. Contam. Toxicol.31(2): 139-147 1983 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 4 days 35000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Dawson,G.W., A.L. Jennings, D. Drozdowski, and E.
Rider		 The Acute Toxicity of 47 Industrial Chemicals to
Fresh and Saltwater Fishes		 J. Hazard. Mater.1(4): 303-318 1977 2016/03/25
魚類 Poecilia reticulata (Guppy) Mortality LC50 96 hours 0.655 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Raevsky, O.A., and Dearden, J.C. Creation of predictive models of aquatic toxicity
of environmental pollutants with different
mechanisms of action on the basis of molecular
similarity and hybot descriptors.		 2004 2016/02/08
魚類 Carassius auratus (Goldfish) Mortality LC50 24 hours 23.2 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Lipnick, R.L., K.R. Watson, and A.K.Strausz A QSAR Study of the Acute Toxicity of Some
Industrial Organic Chemicals to Goldfish.
Narcosis, Electrophile and
Proelectrophile Mechanisms.		 1987 2016/02/08
魚類 Carassius auratus (Goldfish) Lethal EC50 24 hours 23 mg/L 9 ECETOC Aquatic Toxicity, EAT Bridie ea 79 2016/02/08
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 96 hours 12.8 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Eldred, D.V., Weikel C.L., Jurs P.C., and Kaiser
K.L.E.		 Prediction of fathead minnow acute toxicity of
organic compounds from molecular structure.		 1999 2016/02/08
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours 10.6 mg/L 18 既存化学物質安全性(ハザード)評価シート GDCh Advisory Committee on Existing Chemicals BUA Report, 90 1992 2016/03/03
魚類 Cyprinodon variegatus (Sheepshead minnow) LC50 96 hours 11.8 mg/L 18 既存化学物質安全性(ハザード)評価シート GDCh Advisory Committee on Existing Chemicals BUA Report, 90 1992 2016/03/03