【注意事項】
* 化学物質有害性情報データベース情報更新日が2019年9月以前はRead-acrossデータでも○としていないので、毒性値の取り扱いには注意が必要である。
| 生物種 | 学名 | 影響内容 | エンドポイント | 暴露期間(値) | 暴露期間(単位) | 毒性値 | 毒性値(単位) | Read-across * | QSAR | GLP | 設定濃度 | 実測濃度 | 情報源 | 情報源による信頼性評価 | 著者 | タイトル | 記載誌 | 発行年 | 情報更新日 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| subject type | scientific name | effect | endpoint | exposure duration value | exposure duration unit | toxicity value | toxicity unit | Read-across | QSAR | GLP | nominal concentration | measured concentration | original work type | original work reliability rank | author | title | referenced journal | publication year | Information update date |
| 藻類 | Pseudokirchneriella subcapitata | growth rate | 70 | hours | 0.01 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | Oldersma H., Hantsveit A.O. and Rooseboom-Reimers A. | Determination of the effect of hexamethyldisiloxane on the growth of the freshwater green alga Selenastrum|capricornutum. | 2003 | 2018/03/10 | ||||||
| 藻類 | Desmodesmus subspicatus | growth rate | EC50 | 72 | hours | >=1000 | mg/L | ○ | 4 OECD SIDS (HPVC) | 4 | Huls Infracor GmbH | Siliconol NM 1-0.65 Algae Growth Inhibition 86.81.SAG (Algae growth inhibition|following EG 92/69/EEC). | Huls Infracor, Marl, Germany | 1999 | 2018/03/10 | ||||
| 藻類 | Pseudokirchneriella subcapitata | growth rate | ErC50 | 95 | hours | >0.55 | mg/L | 4 OECD SIDS (HPVC) | 2018/03/09 | ||||||||||
| 藻類 | Pseudokirchneriella subcapitata | growth rate | ErC50 | 70 | hours | >0.55 | mg/L | 4 OECD SIDS (HPVC) | 2018/03/09 | ||||||||||
| 藻類 | Pseudokirchneriella subcapitata | growth rate | EC50 | 70 | hours | >0.55 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | Oldersma H., Hantsveit A.O. and Rooseboom-Reimers A. | Determination of the effect of hexamethyldisiloxane on the growth of the freshwater green alga Selenastrum|capricornutum. | 2003 | 2018/03/10 | |||||
| 藻類 | Desmodesmus subspicatus | growth rate | EC50 | 72 | hours | >1000 | mg/L | ○ | 4 OECD SIDS (HPVC) | 4 | Huls Infracor GmbH | Siliconol NM 1-0.65 Algae Growth Inhibition 86.81.SAG (Algae growth inhibition|following EG 92/69/EEC). | Huls Infracor, Marl, Germany | 1999 | 2018/03/10 | ||||
| 藻類 | Desmodesmus subspicatus | growth rate | EC50 | 72 | hours | >32 | mg/L [silicon concentration] | ○ | 4 OECD SIDS (HPVC) | 4 | Huls Infracor GmbH | Siliconol NM 1-0.65 Algae Growth Inhibition 86.81.SAG (Algae growth inhibition|following EG 92/69/EEC). | Huls Infracor, Marl, Germany | 1999 | 2018/03/10 | ||||
| 藻類 | Pseudokirchneriella subcapitata | biomass | EC50 | 95 | hours | 0.22 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | TNO | Determination of the effect of hexamethyldisiloxane on the growth of the freshwater green alga Selenastrum capricornutum. | TNO. Zeist, NL.., Centre Europeen des Silicones | 2003 | 2018/03/10 | ||||
| 藻類 | Pseudokirchneriella subcapitata | biomass | EbC50 | 95 | hours | 0.22 | mg/L | 4 OECD SIDS (HPVC) | 2018/03/09 | ||||||||||
| 藻類 | Pseudokirchneriella subcapitata | growth rate | EC50 | 95 | hours | >0.55 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | TNO | Determination of the effect of hexamethyldisiloxane on the growth of the freshwater green alga Selenastrum capricornutum. | TNO. Zeist, NL.., Centre Europeen des Silicones | 2003 | 2018/03/10 | ||||
| 藻類 | Selenastrum capricornutum | growth rate | ErC50 | 70 | hours | >0.55 | mg/L | 12 ECHA Information on Registered Substances | 2018/02/05 | ||||||||||
| 藻類 | Selenastrum capricornutum | growth rate | ErC10 | 70 | hours | 0.09 | mg/L | 12 ECHA Information on Registered Substances | 2018/02/05 | ||||||||||
| 藻類 | Pseudokirchneriella subcapitata | growth rate | NOEC | 95 | hours | 0.15 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | TNO | Determination of the effect of hexamethyldisiloxane on the growth of the freshwater green alga Selenastrum capricornutum. | TNO. Zeist, NL.., Centre Europeen des Silicones | 2003 | 2018/03/10 | ||||
| 藻類 | Pseudokirchneriella subcapitata | growth rate | NOEC | 95 | hours | 0.15 | mg/L | 4 OECD SIDS (HPVC) | 2018/03/09 | ||||||||||
| 藻類 | Pseudokirchneriella subcapitata | growth rate | LOEC | 95 | hours | 0.28 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | TNO | Determination of the effect of hexamethyldisiloxane on the growth of the freshwater green alga Selenastrum capricornutum. | TNO. Zeist, NL.., Centre Europeen des Silicones | 2003 | 2018/03/10 | ||||
| 藻類 | Pseudokirchneriella subcapitata | growth rate | EC10 | 95 | hours | 0.14 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | TNO | Determination of the effect of hexamethyldisiloxane on the growth of the freshwater green alga Selenastrum capricornutum. | TNO. Zeist, NL.., Centre Europeen des Silicones | 2003 | 2018/03/10 | ||||
| 藻類 | Pseudokirchneriella subcapitata | growth rate | LOEC | 95 | hours | 0.28 | mg/L | 4 OECD SIDS (HPVC) | 2018/03/09 | ||||||||||
| 藻類 | Pseudokirchneriella subcapitata | growth rate | NOEC | 70 | hours | 0.1 | mg/L | 4 OECD SIDS (HPVC) | 2018/03/09 | ||||||||||
| 藻類 | Pseudokirchneriella subcapitata | biomass | EC10 | 95 | hours | 0.05 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | TNO | Determination of the effect of hexamethyldisiloxane on the growth of the freshwater green alga Selenastrum capricornutum. | TNO. Zeist, NL.., Centre Europeen des Silicones | 2003 | 2018/03/10 | ||||
| 藻類 | Pseudokirchneriella subcapitata | growth rate | EC10 | 70 | hours | 0.009 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | Oldersma H., Hantsveit A.O. and Rooseboom-Reimers A. | Determination of the effect of hexamethyldisiloxane on the growth of the freshwater green alga Selenastrum|capricornutum. | 2003 | 2018/03/10 | |||||
| 藻類 | Desmodesmus subspicatus | growth rate | NOEC | 72 | hours | >=32 | mg/L [silicon concentration] | ○ | 4 OECD SIDS (HPVC) | 4 | Huls Infracor GmbH | Siliconol NM 1-0.65 Algae Growth Inhibition 86.81.SAG (Algae growth inhibition|following EG 92/69/EEC). | Huls Infracor, Marl, Germany | 1999 | 2018/03/10 | ||||
| 甲殻類 | Daphnia magna | mobility | EC50 | 48 | hours | >0.37 | mg/L | ○ | 4 OECD SIDS (HPVC) | 3 | Huls Infracor | Siliconol NM 1-0.65 Determination of the acute toxicity to daphnia (Acute toxicity to daphnia test following EG 92/69/EEC). | Hils Infracor GmbH | 1999 | 2018/03/10 | ||||
| 甲殻類 | Daphnia magna | mobility | EC0 | 24 | hours | 50 | mg/L | × | 4 OECD SIDS (HPVC) | 4 | Bayer AG | Internal Company data | 1988 | 2018/03/10 | |||||
| 甲殻類 | Daphnia magna | mobility | EC50 | 24 | hours | 314 | mg/L [ca.] | 4 OECD SIDS (HPVC) | 4 | Grau | Internal report. | Bayer AG | 1991 | 2018/03/10 | |||||
| 甲殻類 | Daphnia magna | mobility | NOEC | 24 | hours | 31.4 | mg/L [ca.] | 4 OECD SIDS (HPVC) | 4 | Grau | Internal report. | Bayer AG | 1991 | 2018/03/10 | |||||
| 甲殻類 | Daphnia magna | mobility | NOEC | 48 | hours | >=0.37 | mg/L | ○ | 4 OECD SIDS (HPVC) | 3 | Huls Infracor | Siliconol NM 1-0.65 Determination of the acute toxicity to daphnia (Acute toxicity to daphnia test following EG 92/69/EEC). | Hils Infracor GmbH | 1999 | 2018/03/10 | ||||
| 甲殻類 | Daphnia magna | mobility | EL50 | 48 | hours | >1000 | mg/L | ○ | 4 OECD SIDS (HPVC) | 3 | Huls Infracor | Siliconol NM 1-0.65 Determination of the acute toxicity to daphnia (Acute toxicity to daphnia test following EG 92/69/EEC). | Hils Infracor GmbH | 1999 | 2018/03/10 | ||||
| 甲殻類 | Daphnia magna | mobility | NOELR | 48 | hours | >=1000 | mg/L | ○ | 4 OECD SIDS (HPVC) | 3 | Huls Infracor | Siliconol NM 1-0.65 Determination of the acute toxicity to daphnia (Acute toxicity to daphnia test following EG 92/69/EEC). | Hils Infracor GmbH | 1999 | 2018/03/10 | ||||
| 甲殻類 | Daphnia magna | mobility | EC50 | 48 | hours | >11 | mg/L [silicon content] | ○ | 4 OECD SIDS (HPVC) | 3 | Huls Infracor | Siliconol NM 1-0.65 Determination of the acute toxicity to daphnia (Acute toxicity to daphnia test following EG 92/69/EEC). | Hils Infracor GmbH | 1999 | 2018/03/10 | ||||
| 甲殻類 | Daphnia magna | mobility | NOEC | 48 | hours | >=11 | mg/L [silicon content] | ○ | 4 OECD SIDS (HPVC) | 3 | Huls Infracor | Siliconol NM 1-0.65 Determination of the acute toxicity to daphnia (Acute toxicity to daphnia test following EG 92/69/EEC). | Hils Infracor GmbH | 1999 | 2018/03/10 | ||||
| 甲殻類 | Daphnia magna | mobility | EC100 | 24 | hours | >400 | mg/L | × | 4 OECD SIDS (HPVC) | 4 | Bayer AG | Internal Company data | 1988 | 2018/03/10 | |||||
| 甲殻類 | Daphnia magna | mortality | LOEC | 21 | days | 0.44 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | TNO | Semi-static reproduction test with hexamethyldisiloxane and Daphnia magna ( OECD Guideline No.211). | TNO, Zeist, The Netherlands | 1988 | 2018/03/10 | ||||
| 甲殻類 | Daphnia magna | reproduction | EC50 | 21 | days | 0.3 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | TNO | Semi-static reproduction test with hexamethyldisiloxane and Daphnia magna ( OECD Guideline No.211). | TNO, Zeist, The Netherlands | 1988 | 2018/03/10 | ||||
| 甲殻類 | Daphnia magna | mortality | LC50 | 21 | days | 0.45 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | TNO | Semi-static reproduction test with hexamethyldisiloxane and Daphnia magna ( OECD Guideline No.211). | TNO, Zeist, The Netherlands | 1988 | 2018/03/10 | ||||
| 甲殻類 | Daphnia magna | condition | LOEC | 21 | days | 0.44 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | TNO | Semi-static reproduction test with hexamethyldisiloxane and Daphnia magna ( OECD Guideline No.211). | TNO, Zeist, The Netherlands | 1988 | 2018/03/10 | ||||
| 甲殻類 | Daphnia magna | reproduction | LOEC | 21 | days | 0.14 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | TNO | Semi-static reproduction test with hexamethyldisiloxane and Daphnia magna ( OECD Guideline No.211). | TNO, Zeist, The Netherlands | 1988 | 2018/03/10 | ||||
| 甲殻類 | Daphnia magna | mortality | NOEC | 21 | days | 0.25 | mg/L | 4 OECD SIDS (HPVC) | 2018/03/09 | ||||||||||
| 甲殻類 | Daphnia magna | mortality | NOEC | 21 | days | 0.25 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | TNO | Semi-static reproduction test with hexamethyldisiloxane and Daphnia magna ( OECD Guideline No.211). | TNO, Zeist, The Netherlands | 1988 | 2018/03/10 | ||||
| 甲殻類 | Daphnia magna | reproduction | LOEC | 21 | days | 0.14 | mg/L | 4 OECD SIDS (HPVC) | 2018/03/09 | ||||||||||
| 甲殻類 | Daphnia magna | EC50 | 21 | days | 0.45 | mg/L | 4 OECD SIDS (HPVC) | 2018/03/09 | |||||||||||
| 甲殻類 | Daphnia magna | condition | NOEC | 21 | days | 0.25 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | TNO | Semi-static reproduction test with hexamethyldisiloxane and Daphnia magna ( OECD Guideline No.211). | TNO, Zeist, The Netherlands | 1988 | 2018/03/10 | ||||
| 甲殻類 | Daphnia magna | reproduction | NOEC | 21 | days | 0.08 | mg/L | 4 OECD SIDS (HPVC) | 2018/03/09 | ||||||||||
| 甲殻類 | Daphnia magna | condition | NOEC | 21 | days | 0.25 | mg/L | 4 OECD SIDS (HPVC) | 2018/03/09 | ||||||||||
| 甲殻類 | Daphnia magna | condition | LOEC | 21 | days | 0.44 | mg/L | 4 OECD SIDS (HPVC) | 2018/03/09 | ||||||||||
| 甲殻類 | Daphnia magna | reproduction | NOEC | 21 | days | 0.08 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | TNO | Semi-static reproduction test with hexamethyldisiloxane and Daphnia magna ( OECD Guideline No.211). | TNO, Zeist, The Netherlands | 1988 | 2018/03/10 | ||||
| 甲殻類 | Daphnia magna | reproduction | NOEC | 21 | days | 0.08 | mg/L | 12 ECHA Information on Registered Substances | 2018/02/05 | ||||||||||
| 甲殻類 | Daphnia magna | reproduction | EC50 | 21 | days | 0.3 | mg/L | 12 ECHA Information on Registered Substances | 2018/02/05 | ||||||||||
| 魚類 | Pimephales promelas (Fathead minnow) | LC50 | 14 | days | >0.093 | mg/L | 4 OECD SIDS (HPVC) | 2018/03/09 | |||||||||||
| 魚類 | Oryzias latipes (Japanese medaka) | mortality | NOEC | 48 | hours | 0.639 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | Matsunobu, Y. | Bioaccumulation test of LS-7130 in Carp | Kurume Research Laboratories, Japan | 1995 | 2018/03/10 | ||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | mortality | NOEC | 9 | days | >=0.095 | mg/L | ○ | 4 OECD SIDS (HPVC) | 4 | Dow Corning Corporation | An Attempt to Access the Lethal Body Burden of Me3SiOSiMe3 to Rainbow Trout | 1990 | 2018/03/10 | |||||
| 魚類 | Cyprinus carpio (Carp) | mortality | NOELR | 96 | hours | >=1000 | mg/L | ○ | 4 OECD SIDS (HPVC) | 4 | Huls Infracor | Siliconol NM 1-0.65 Determination of the acute toxicity to fish (Acute toxicity to fish test following EG 92/69/EWG EEC). | Degussa-Huls AG , FK 1401. Degussa-Huls AG-Nr.: 99-0065-DGO | 1999 | 2018/03/10 | ||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | mortality | LC50 | 9 | days | >0.095 | mg/L | ○ | 4 OECD SIDS (HPVC) | 4 | Dow Corning Corporation | An Attempt to Access the Lethal Body Burden of Me3SiOSiMe3 to Rainbow Trout | 1990 | 2018/03/10 | |||||
| 魚類 | Pimephales promelas (Fathead minnow) | mortality | LC50 | 14 | days | >0.093 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | Annelin, R.B. and J.L. Hamelink | A fourteen day aquatic toxicity test of hexamethyl disiloxane in fathead minnow under flow-through saturated conditions. | Dow Corning Corporation | 1990 | 2018/03/10 | ||||
| 魚類 | Pimephales promelas (Fathead minnow) | mortality | NOEC | 14 | days | >=0.093 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | Annelin, R.B. and J.L. Hamelink | A fourteen day aquatic toxicity test of hexamethyl disiloxane in fathead minnow under flow-through saturated conditions. | Dow Corning Corporation | 1990 | 2018/03/10 | ||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | LC50 | 96 | hours | 0.46 | mg/L | 4 OECD SIDS (HPVC) | 2018/03/09 | |||||||||||
| 魚類 | Cyprinus carpio (Carp) | mortality | NOEC | 96 | hours | >=13.5 | mg/L [silicon content] | ○ | 4 OECD SIDS (HPVC) | 4 | Huls Infracor | Siliconol NM 1-0.65 Determination of the acute toxicity to fish (Acute toxicity to fish test following EG 92/69/EWG EEC). | Degussa-Huls AG , FK 1401. Degussa-Huls AG-Nr.: 99-0065-DGO | 1999 | 2018/03/10 | ||||
| 魚類 | Cyprinus carpio (Carp) | mortality | LC50 | 96 | hours | >13.5 | mg/L [silicon content] | ○ | 4 OECD SIDS (HPVC) | 4 | Huls Infracor | Siliconol NM 1-0.65 Determination of the acute toxicity to fish (Acute toxicity to fish test following EG 92/69/EWG EEC). | Degussa-Huls AG , FK 1401. Degussa-Huls AG-Nr.: 99-0065-DGO | 1999 | 2018/03/10 | ||||
| 魚類 | Oryzias latipes (Japanese medaka) | mortality | LC50 | 48 | hours | 1.27 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | Matsunobu, Y. | Bioaccumulation test of LS-7130 in Carp | Kurume Research Laboratories, Japan | 1995 | 2018/03/10 | ||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | mortality | LC50 | 96 | hours | 3.02 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | Bayer AG | Hexamethyldisiloxan (M2), acute toxicity to rainbow trout in a flow-through test. | Bayer AG. internal report. FF-313 | 2018/03/10 | |||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | mortality | NOEC | 96 | hours | 0.28 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | Bayer AG | Hexamethyldisiloxan (M2), acute toxicity to rainbow trout in a flow-through test. | Bayer AG. internal report. FF-313 | 2018/03/10 | |||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | mortality | LC50 | 96 | hours | 0.46 | mg/L | ○ | 4 OECD SIDS (HPVC) | 2 | Bayer AG | Hexamethyldisiloxan (M2), acute toxicity to rainbow trout in a flow-through test. | Bayer AG. internal report. FF-313 | 2018/03/10 | |||||
| 魚類 | Cyprinus carpio (Carp) | mortality | LL50 | 96 | hours | >1000 | mg/L | ○ | 4 OECD SIDS (HPVC) | 4 | Huls Infracor | Siliconol NM 1-0.65 Determination of the acute toxicity to fish (Acute toxicity to fish test following EG 92/69/EWG EEC). | Degussa-Huls AG , FK 1401. Degussa-Huls AG-Nr.: 99-0065-DGO | 1999 | 2018/03/10 | ||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | mortality | NOEC | 96 | hours | 0.28 | mg/L | 12 ECHA Information on Registered Substances | 2018/02/05 | ||||||||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | mortality | LC50 | 96 | hours | 3.02 | mg/L | 12 ECHA Information on Registered Substances | 2018/02/05 | ||||||||||
| 魚類 | Cyprinus carpio (Carp) | mortality, behaviour and appearance | NOEC | 10 | weeks | >=2.4 | μg/L | ○ | 4 OECD SIDS (HPVC) | 3 | Kurume Research Laboratories | Bioaccumulation test of LS-7130 in Carp. | Kurume Research Laboratories, Japan | 1995 | 2018/03/10 | ||||
| 魚類 | Cyprinus carpio (Carp) | mortality, behaviour and appearance | NOEC | 8 | weeks | >=40 | μg/L | ○ | 4 OECD SIDS (HPVC) | 3 | Kurume Research Laboratories | Bioaccumulation test of LS-7130 in Carp. | Kurume Research Laboratories, Japan | 1995 | 2018/03/10 | ||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | embryo survival, larval hatch and growth (length and dry weight) | NOEC | 90 | days | >=27 | μg/L | 12 ECHA Information on Registered Substances | Springborn Smithers | 2010 | 2018/03/03 |