生態影響に係る有害性情報


CAS登録番号 CAS RN ® ： 108-38-3
官報公示整理番号　METI No. ： 3-60/3-3
物質名 test material ： ｍ－キシレン　／m-Xylene
水溶解度 water solubility ： 161mg/L (推計値 estimated)
LogKow ： 3.2 (実測値 measured)
備考 remarks ：
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書） / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし　4:情報が少なく評価不能
日本環境省　化学物質の環境リスク評価（生態リスク初期評価） A：試験は信頼できる　B：試験は条件付きで信頼できる　C：試験の信頼性は低い　D：信頼性の判定不可　E：信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり　Supplemental:条件付きで信頼性あり　Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり：○
なし：×		 情報源 情報源による
信頼性評価**		 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value		 exposure
duration
unit		 toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material		 original work type original work
reliability rank		 author title referenced journal publication year Information
update date
藻類 Pseudokirchneriella subcapitata Growth EC50 3 days 4900 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Galassi,S., M. Mingazzini, L. Vigano, D. Cesareo,
and M.L. Tosato		 Approaches to Modeling Toxic Responses of Aquatic
Organisms to Aromatic Hydrocarbons		 Ecotoxicol. Environ. Saf.16(2): 158-169 1988 2016/03/25
藻類 Pseudokirchneriella subcapitata Growth EC50 8 days 3900 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Herman,D.C., W.E. Inniss, and C.I. Mayfield Impact of Volatile Aromatic Hydrocarbons, Alone
and in Combination, on Growth of the Freshwater
Alga Selenastrum capricornutum		 Aquat. Toxicol.18(2): 87-100 1990 2016/03/25
藻類 Selenastrum capricornutum Growth EC50 192 hours 3.9 mg/L 9 ECETOC Aquatic Toxicity, EAT Herman ea 90 2016/02/08
藻類 Selenastrum capricornutum Growth EC50 192 hours 3.9 mg/L 9 ECETOC Aquatic Toxicity, EAT Herman ea 90 2016/02/08
甲殻類 Daphnia magna Mortality LC50 2 days 23600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 MacLean,M.M., and K.G. Doe The Comparative Toxicity of Crude and Refined
Oils to Daphnia magna and Artemia		 Environment Canada, EE-111, Dartmouth, Nova
Scotia:64 p.		 1989 2016/03/25
甲殻類 Daphnia magna Physiology EC50 2 days 3530 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 MacLean,M.M., and K.G. Doe The Comparative Toxicity of Crude and Refined
Oils to Daphnia magna and Artemia		 Environment Canada, EE-111, Dartmouth, Nova
Scotia:64 p.		 1989 2016/03/25
甲殻類 Ceriodaphnia dubia Physiology EC50 2 days 23 μmol/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Rose,R.M., M.St.J. Warne, and R.P. Lim Quantitative Structure-Activity Relationships and
Volume Fraction Analysis for Nonpolar Narcotic
Chemicals to the Australian Cladoceran
Ceriodaphnia cf. dubia		 Arch. Environ. Contam. Toxicol.34(3): 248-252 1998 2016/03/25
甲殻類 Daphnia magna Physiology EC50 1 days 4700 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Galassi,S., M. Mingazzini, L. Vigano, D. Cesareo,
and M.L. Tosato		 Approaches to Modeling Toxic Responses of Aquatic
Organisms to Aromatic Hydrocarbons		 Ecotoxicol. Environ. Saf.16(2): 158-169 1988 2016/03/25
甲殻類 Daphnia magna Mortality LC50 2 days 55700 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 MacLean,M.M., and K.G. Doe The Comparative Toxicity of Crude and Refined
Oils to Daphnia magna and Artemia		 Environment Canada, EE-111, Dartmouth, Nova
Scotia:64 p.		 1989 2016/03/25
甲殻類 Daphnia magna Physiology EC50 2 days 90 mmol/m3 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Bobra,A.M., W.Y. Shiu, and D. Mackay A Predictive Correlation for the Acute Toxicity
of Hydrocarbons and Chlorinated Hydrocarbons to
the Water Flea (Daphnia magna)		 Chemosphere12(9-10): 1121-1129 1983 2016/03/25
甲殻類 Daphnia magna Physiology EC50 2 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 MacLean,M.M., and K.G. Doe The Comparative Toxicity of Crude and Refined
Oils to Daphnia magna and Artemia		 Environment Canada, EE-111, Dartmouth, Nova
Scotia:64 p.		 1989 2016/03/25
甲殻類 Daphnia magna Intoxication ET50 24 hours 11.1 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Urrestarazu Ramos, E. Aquatic toxicity of polar narcotic pollutants/
Mechanism, modeling and environmental effect
assessment (PhD Thesis)		 1998 2016/02/08
甲殻類 Ceriodaphnia dubia Lethal EC50 168 hours 2.97 mg/L 9 ECETOC Aquatic Toxicity, EAT Niederlehner ea 98 2016/02/08
甲殻類 Daphnia magna Lethal EC50 48 hours 14.333 mg/L 9 ECETOC Aquatic Toxicity, EAT Hermens ea 84 2016/02/08
甲殻類 Daphnia magna Intoxication IC50 24 hours 19.3 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Zhao, Y.H., Ji G.D., Cronin M.T.D., Dearden J.C. QSAR study of the toxicity of benzoic acids to
Vibrio fischeri, Daphnia magna and carp.		 1998 2016/02/08
甲殻類 Daphnia magna Mortality LC50 48 hours 15 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Hermens, J. Broerkhuyzen , E. Canton, H; Wegeman,
R.		 Quantitative structure-activity, relationships
and mixture toxicity studies of alcohols and
chlorohydrocarbons; Effects on growth of
Daphnia magna.		 1985 2016/02/08
甲殻類 Ceriodaphnia dubia Reproduction EC50 168 hours 2.76 mg/L 9 ECETOC Aquatic Toxicity, EAT Niederlehner ea 98 2016/02/08
甲殻類 Ceriodaphnia dubia Reproduction NOEC 168 hours 1.17 mg/L 9 ECETOC Aquatic Toxicity, EAT Niederlehner ea 98 2016/02/08
甲殻類 Ceriodaphnia dubia Reproduction LOEC 168 hours 2.55 mg/L 9 ECETOC Aquatic Toxicity, EAT Niederlehner ea 98 2016/02/08
魚類 Poecilia reticulata (Guppy) Mortality LC50 4 days 12900 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Galassi,S., M. Mingazzini, L. Vigano, D. Cesareo,
and M.L. Tosato		 Approaches to Modeling Toxic Responses of Aquatic
Organisms to Aromatic Hydrocarbons		 Ecotoxicol. Environ. Saf.16(2): 158-169 1988 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 4 days 8400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Galassi,S., M. Mingazzini, L. Vigano, D. Cesareo,
and M.L. Tosato		 Approaches to Modeling Toxic Responses of Aquatic
Organisms to Aromatic Hydrocarbons		 Ecotoxicol. Environ. Saf.16(2): 158-169 1988 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 16000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Geiger,D.L., L.T. Brooke, and D.J. Call Acute Toxicities of Organic Chemicals to Fathead
Minnows (Pimephales promelas), Volume V		 Center for Lake Superior Environmental Studies,
University of Wisconsin, Superior, WI:332 p.		 1990 2016/03/25
魚類 Carassius auratus (Goldfish) Mortality LC50 1 days 16000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Bridie,A.L., C.J.M. Wolff, and M. Winter The Acute Toxicity of Some Petrochemicals to
Goldfish		 Water Res.13(7): 623-626 1979 2016/03/25
魚類 Cyprinus carpio (Carp) Mortality 7 days 1500000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Funasaka,R., Y. Ose, and T. Sato Studies on the Offensive-Odor Fish of the Nagara
River. VII. Median Tolerance Limit Test of the
Offensive-Odor Substances		 Eisei Kagaku22(1): 20-23 1976 2016/03/25
魚類 Poecilia reticulata (Guppy) Mortality LC50 96 hours 37.7 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Urrestarazu Ramos, E. Aquatic toxicity of polar narcotic pollutants/
Mechanism, modeling and environmental effect
assessment (PhD Thesis)		 1998 2016/02/08
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 96 hours 16.1 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Russom, C.L., Bradbury, S.P., Broderius, S.J.,
Drummond, R.A. and Hammermeister, D.E.		 PREDICTING MODES OF TOXIC ACTION FROM CHEMICAL
STRUCTURE: ACUTE TOXICITY IN THE FATHEAD MINNOW
(PIMEPHALES PROMELAS)		 1997 2016/02/08
魚類 Carassius auratus (Goldfish) Mortality LC50 24 hours 16.1 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Lipnick, R.L., K.R. Watson, and A.K.Strausz A QSAR Study of the Acute Toxicity of Some
Industrial Organic Chemicals to Goldfish.
Narcosis, Electrophile and
Proelectrophile Mechanisms.		 1987 2016/02/08
魚類 Carassius auratus (Goldfish) Lethal EC50 24 hours 16 mg/L 9 ECETOC Aquatic Toxicity, EAT Bridie ea 79 2016/02/08
魚類 Poecilia reticulata (Guppy) Mortality LC50 96 hours 48.5 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Raevsky, O.A., and Dearden, J.C. Creation of predictive models of aquatic toxicity
of environmental pollutants with different
mechanisms of action on the basis of molecular
similarity and hybot descriptors.		 2004 2016/02/08