【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。
| 生物種 | 学名 | 影響内容 | エンドポイント | 暴露期間(値) | 暴露期間(単位) | 毒性値 | 毒性値(単位) | 毒性値(単位)種別 | 試験中の 被験物質 濃度測定 あり：○ なし：× |
情報源 | 情報源による 信頼性評価** |
著者 | タイトル | 記載誌 | 発行年 | 情報更新日 | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| subject type | scientific name | effect | endpoint | exposure duration value |
exposure duration unit |
toxicity value | toxicity unit | toxicity unit type | Read-across* | QSAR | GLP | measurement of the test material |
original work type | original work reliability rank |
author | title | referenced journal | publication year | Information update date |
| 甲殻類 | Daphnia magna | Mortality | 1 | days | 0.0001 | mol/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Stom,D.I., and L.D. Zubareva | Comparative Resistance of Daphnia and Epischura to Toxic Substances in Acute Exposure | Hydrobiol. J.30(3): 35-38 | 1994 | 2016/03/25 | |||||||
| 甲殻類 | Daphnia magna | Behavior | 2 | days | 800 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Bringmann,G., and R. Kuhn | Comparative Water-Toxicological Investigations on Bacteria, Algae, and Daphnia | TR-TS-002, Literature Research Company, Annandale, VA:26 p. | 1959 | 2016/03/25 | |||||||
| 甲殻類 | Daphnia magna | Mortality | 1 | days | 0.001 | mol/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Stom,D.I., and L.D. Zubareva | Comparative Resistance of Daphnia and Epischura to Toxic Substances in Acute Exposure | Hydrobiol. J.30(3): 35-38 | 1994 | 2016/03/25 | |||||||
| 甲殻類 | Daphnia magna | Mortality | 1 | days | 0.01 | mol/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Stom,D.I., and L.D. Zubareva | Comparative Resistance of Daphnia and Epischura to Toxic Substances in Acute Exposure | Hydrobiol. J.30(3): 35-38 | 1994 | 2016/03/25 | |||||||
| 甲殻類 | Daphnia sp. | Mortality | LD50 | 2 | days | 800000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Bringmann,G., and R. Kuhn | The Water-Toxicological Detection of Insecticides (Zum Wasser-Toxikologischen Nachweis von Insektiziden) | Gesund. -Ing.8:243-244 | 1960 | 2016/03/25 | ||||||
| 甲殻類 | Daphnia magna | Mortality | LC50 | 4 | days | 250 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Ewell,W.S., J.W. Gorsuch, R.O. Kringle, K.A. Robillard, and R.C. Spiegel | Simultaneous Evaluation of the Acute Effects of Chemicals on Seven Aquatic Species | Environ. Toxicol. Chem.5(9): 831-840 | 1986 | 2016/03/25 | ||||||
| 甲殻類 | Daphnia magna | Mortality | 5 | days | 25 | nmol/ml | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Sutfeld,R., F. Petereit, and A. Nahrstedt | Resorcinol in Exudates of Nuphar lutea | J. Chem. Ecol.22(12): 2221-2231 | 1996 | 2016/03/25 | |||||||
| 甲殻類 | Daphnia magna | Intoxication | ET50 | 48 | hours | 108 | mg/L | 17 Aquatic OASIS (OECD QSAR Toolbox) | Furusjö, E., Andersson, M., Rahmberg, M., Svenson, A. | Estimating environmentally important properties of chemicals from the chemical structure | 2003 | 2016/02/08 | |||||||
| 甲殻類 | Daphnia magna | Intoxication | IC50 | 24 | hours | 55.2 | mg/L | 17 Aquatic OASIS (OECD QSAR Toolbox) | Zhao, Y.H., Ji G.D., Cronin M.T.D., Dearden J.C. | QSAR study of the toxicity of benzoic acids to Vibrio fischeri, Daphnia magna and carp. | 1998 | 2016/02/08 | |||||||
| 魚類 | Danio rerio (Zebrafish) | Biochemical | LOEC | 3 | days | 50 | μM | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Thienpont,B., A. Tingaud-Sequeira, E. Prats, C. Barata, P.J. Babin, and D. Raldua | Zebrafish Eleutheroembryos Provide a Suitable Vertebrate Model for Screening Chemicals that Impair Thyroid Hormone Synthesis | Environ. Sci. Technol.45(17): 7525-7532 | 2011 | 2016/03/25 | ||||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | No Group Code | LOEC | 60 | days | 320000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek | Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds | Ecotoxicol. Environ. Saf.20(1): 42-52 | 1990 | 2016/03/25 | ||||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | Growth | LOEC | 60 | days | 100000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek | Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds | Ecotoxicol. Environ. Saf.20(1): 42-52 | 1990 | 2016/03/25 | ||||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | Mortality | LOEC | 60 | days | 320000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek | Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds | Ecotoxicol. Environ. Saf.20(1): 42-52 | 1990 | 2016/03/25 | ||||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | Mortality | LC50 | 4 | days | >100000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | DeGraeve,G.M., D.L. Geiger, J.S. Meyer, and H.L. Bergman | Acute and Embryo-Larval Toxicity of Phenolic Compounds to Aquatic Biota | Arch. Environ. Contam. Toxicol.9(5): 557-568 | 1980 | 2016/03/25 | ||||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | Mortality | 4 | days | 50000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Bergman,H.L., and A.D. Anderson | Effects of Aqueous Effluents from In Situ Fossil Fuel Processing Technologies on Aquatic Systems | Contract No.EY-77-C-04-3913, University of Wyoming, Laramie, WY:73 p. | 1977 | 2016/03/25 | |||||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | Growth | LOEC | 60 | days | 32000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek | Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds | Ecotoxicol. Environ. Saf.20(1): 42-52 | 1990 | 2016/03/25 | ||||||
| 魚類 | Danio rerio (Zebrafish) | Biochemical | EC10 | 3 | days | 2 | μM | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Thienpont,B., A. Tingaud-Sequeira, E. Prats, C. Barata, P.J. Babin, and D. Raldua | Zebrafish Eleutheroembryos Provide a Suitable Vertebrate Model for Screening Chemicals that Impair Thyroid Hormone Synthesis | Environ. Sci. Technol.45(17): 7525-7532 | 2011 | 2016/03/25 | ||||||
| 魚類 | Carassius auratus (Goldfish) | Mortality | 2 | days | 57400 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Sollmann,T. | Correlation of the Aquarium Goldfish Toxicities of Some Phenols, Quinones, and Other Benzene Derivatives with Their Inhibition of Autooxidative | J. Gen. Physiol.32:671-679 | 1949 | 2016/03/25 | |||||||
| 魚類 | Pimephales promelas (Fathead minnow) | Mortality | LC50 | 2 | days | 72600 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Curtis,M.W., T.L. Copeland, and C.H. Ward | Acute Toxicity of 12 Industrial Chemicals to Freshwater and Saltwater Organisms | Water Res.13(2): 137-141 | 1979 | 2016/03/25 | ||||||
| 魚類 | Danio rerio (Zebrafish) | Biochemical | NOEC | 3 | days | 10 | μM | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Thienpont,B., A. Tingaud-Sequeira, E. Prats, C. Barata, P.J. Babin, and D. Raldua | Zebrafish Eleutheroembryos Provide a Suitable Vertebrate Model for Screening Chemicals that Impair Thyroid Hormone Synthesis | Environ. Sci. Technol.45(17): 7525-7532 | 2011 | 2016/03/25 | ||||||
| 魚類 | Pimephales promelas (Fathead minnow) | Mortality | LC50 | 4 | days | 53400 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Curtis,M.W., T.L. Copeland, and C.H. Ward | Acute Toxicity of 12 Industrial Chemicals to Freshwater and Saltwater Organisms | Water Res.13(2): 137-141 | 1979 | 2016/03/25 | ||||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | Growth | EC50 | 60 | days | 260000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek | Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds | Ecotoxicol. Environ. Saf.20(1): 42-52 | 1990 | 2016/03/25 | ||||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | Mortality | LC50 | 60 | days | 320000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek | Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds | Ecotoxicol. Environ. Saf.20(1): 42-52 | 1990 | 2016/03/25 | ||||||
| 魚類 | Pimephales promelas (Fathead minnow) | Mortality | LC50 | 1 | days | 88600 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Curtis,M.W., T.L. Copeland, and C.H. Ward | Acute Toxicity of 12 Industrial Chemicals to Freshwater and Saltwater Organisms | Water Res.13(2): 137-141 | 1979 | 2016/03/25 | ||||||
| 魚類 | Pimephales promelas (Fathead minnow) | Mortality | 4 | days | 25000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Bergman,H.L., and A.D. Anderson | Effects of Aqueous Effluents from In Situ Fossil Fuel Processing Technologies on Aquatic Systems | Contract No.EY-77-C-04-3913, University of Wyoming, Laramie, WY:73 p. | 1977 | 2016/03/25 | |||||||
| 魚類 | Pimephales promelas (Fathead minnow) | Mortality | LC50 | 4 | days | 60000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Curtis,M.W., and C.H. Ward | Aquatic Toxicity of Forty Industrial Chemicals: Testing in Support of Hazardous Substance Spill Prevention Regulation | J. Hydrol.51:359-367 | 1981 | 2016/03/25 | ||||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | Mortality | 4 | days | 100000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Bergman,H.L., and A.D. Anderson | Effects of Aqueous Effluents from In Situ Fossil Fuel Processing Technologies on Aquatic Systems | Contract No.EY-77-C-04-3913, University of Wyoming, Laramie, WY:73 p. | 1977 | 2016/03/25 | |||||||
| 魚類 | Pimephales promelas (Fathead minnow) | Mortality | LC50 | 4 | days | 40000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Ewell,W.S., J.W. Gorsuch, R.O. Kringle, K.A. Robillard, and R.C. Spiegel | Simultaneous Evaluation of the Acute Effects of Chemicals on Seven Aquatic Species | Environ. Toxicol. Chem.5(9): 831-840 | 1986 | 2016/03/25 | ||||||
| 魚類 | Danio rerio (Zebrafish) | Growth | EC50 | 7 | days | 54800 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek | Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds | Ecotoxicol. Environ. Saf.20(1): 42-52 | 1990 | 2016/03/25 | ||||||
| 魚類 | Danio rerio (Zebrafish) | Mortality | LC10 | 3 | days | 4164 | μM | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Thienpont,B., A. Tingaud-Sequeira, E. Prats, C. Barata, P.J. Babin, and D. Raldua | Zebrafish Eleutheroembryos Provide a Suitable Vertebrate Model for Screening Chemicals that Impair Thyroid Hormone Synthesis | Environ. Sci. Technol.45(17): 7525-7532 | 2011 | 2016/03/25 | ||||||
| 魚類 | Danio rerio (Zebrafish) | No Group Code | LOEC | 7 | days | 100000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek | Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds | Ecotoxicol. Environ. Saf.20(1): 42-52 | 1990 | 2016/03/25 | ||||||
| 魚類 | Danio rerio (Zebrafish) | Mortality | LC50 | 3 | days | 5003 | μM | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Thienpont,B., A. Tingaud-Sequeira, E. Prats, C. Barata, P.J. Babin, and D. Raldua | Zebrafish Eleutheroembryos Provide a Suitable Vertebrate Model for Screening Chemicals that Impair Thyroid Hormone Synthesis | Environ. Sci. Technol.45(17): 7525-7532 | 2011 | 2016/03/25 | ||||||
| 魚類 | Pimephales promelas (Fathead minnow) | Mortality | LC50 | 4 | days | 100000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Bergman,H.L., and A.D. Anderson | Effects of Aqueous Effluents from In Situ Fossil Fuel Processing Technologies on Aquatic Systems | Contract No.EY-77-C-04-3913, University of Wyoming, Laramie, WY:73 p. | 1977 | 2016/03/25 | ||||||
| 魚類 | Pimephales promelas (Fathead minnow) | Mortality | LC50 | 4 | days | 56500 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Curtis,M.W., T.L. Copeland, and C.H. Ward | Aquatic Toxicity of Substances Proposed for Spill Prevention Regulation | In: Proc. Natl. Conf. Control of Hazardous Material Spills, Miami Beach, FL:99-103 | 1978 | 2016/03/25 | ||||||
| 魚類 | Pimephales promelas (Fathead minnow) | Mortality | LC50 | 2 | days | 72600 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Curtis,M.W., T.L. Copeland, and C.H. Ward | Aquatic Toxicity of Substances Proposed for Spill Prevention Regulation | In: Proc. Natl. Conf. Control of Hazardous Material Spills, Miami Beach, FL:99-103 | 1978 | 2016/03/25 | ||||||
| 魚類 | Pimephales promelas (Fathead minnow) | Mortality | LC50 | 4 | days | 100000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | DeGraeve,G.M., D.L. Geiger, J.S. Meyer, and H.L. Bergman | Acute and Embryo-Larval Toxicity of Phenolic Compounds to Aquatic Biota | Arch. Environ. Contam. Toxicol.9(5): 557-568 | 1980 | 2016/03/25 | ||||||
| 魚類 | Pimephales promelas (Fathead minnow) | Mortality | LC50 | 1 | days | 88600 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Curtis,M.W., T.L. Copeland, and C.H. Ward | Aquatic Toxicity of Substances Proposed for Spill Prevention Regulation | In: Proc. Natl. Conf. Control of Hazardous Material Spills, Miami Beach, FL:99-103 | 1978 | 2016/03/25 | ||||||
| 魚類 | Pimephales promelas (Fathead minnow) | Mortality | LC50 | 4 | days | 49500 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Curtis,M.W., T.L. Copeland, and C.H. Ward | Aquatic Toxicity of Substances Proposed for Spill Prevention Regulation | In: Proc. Natl. Conf. Control of Hazardous Material Spills, Miami Beach, FL:99-103 | 1978 | 2016/03/25 | ||||||
| 魚類 | Danio rerio (Zebrafish) | Mortality | LOEC | 7 | days | 320000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek | Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds | Ecotoxicol. Environ. Saf.20(1): 42-52 | 1990 | 2016/03/25 | ||||||
| 魚類 | Danio rerio (Zebrafish) | Biochemical | LOEC | 3 | days | 200000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Thienpont,B., A. Tingaud-Sequeira, E. Prats, C. Barata, P.J. Babin, and D. Raldua | Zebrafish Eleutheroembryos Provide a Suitable Vertebrate Model for Screening Chemicals that Impair Thyroid Hormone Synthesis | Environ. Sci. Technol.45(17): 7525-7532 | 2011 | 2016/03/25 | ||||||
| 魚類 | Danio rerio (Zebrafish) | Mortality | LC50 | 7 | days | 262000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek | Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds | Ecotoxicol. Environ. Saf.20(1): 42-52 | 1990 | 2016/03/25 | ||||||
| 魚類 | Danio rerio (Zebrafish) | Biochemical | EC50 | 3 | days | 82 | μM | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Thienpont,B., A. Tingaud-Sequeira, E. Prats, C. Barata, P.J. Babin, and D. Raldua | Zebrafish Eleutheroembryos Provide a Suitable Vertebrate Model for Screening Chemicals that Impair Thyroid Hormone Synthesis | Environ. Sci. Technol.45(17): 7525-7532 | 2011 | 2016/03/25 | ||||||
| 魚類 | Pimephales promelas (Fathead minnow) | Mortality | LC50 | 96 | hours | 50.3 | mg/L | 17 Aquatic OASIS (OECD QSAR Toolbox) | Russom, C.L., Bradbury, S.P., Broderius, S.J., Drummond, R.A. and Hammermeister, D.E. | PREDICTING MODES OF TOXIC ACTION FROM CHEMICAL STRUCTURE: ACUTE TOXICITY IN THE FATHEAD MINNOW (PIMEPHALES PROMELAS) | 1997 | 2016/02/08 | |||||||
| 魚類 | Pimephales promelas (Fathead minnow) | Lethal | EC50 | 96 | hours | 49.5 | mg/L | 9 ECETOC Aquatic Toxicity, EAT | Curtis ea 79 | 2016/02/08 | |||||||||
| 魚類 | Poecilia reticulata (Guppy) | Mortality | LC50 | 96 | hours | 100 | mg/L | 17 Aquatic OASIS (OECD QSAR Toolbox) | Raevsky, O.A., and Dearden, J.C. | Creation of predictive models of aquatic toxicity of environmental pollutants with different mechanisms of action on the basis of molecular similarity and hybot descriptors. | 2004 | 2016/02/08 | |||||||
| 魚類 | Pimephales promelas (Fathead minnow) | Lethal | EC50 | 96 | hours | 60 | mg/L | 9 ECETOC Aquatic Toxicity, EAT | Curtis and Ward 81 | 2016/02/08 |