生態影響に係る有害性情報


CAS登録番号 CAS RN ® ： 111-46-6
官報公示整理番号　METI No. ： 2-415
物質名 test material ： ジエチレングリコール　／Ethanol, 2,2'-oxybis-
水溶解度 water solubility ： 1000000mg/L (推計値 estimated)
LogKow ： -1.47 (推計値 estimated)
備考 remarks ：
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書） / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし　4:情報が少なく評価不能
日本環境省　化学物質の環境リスク評価（生態リスク初期評価） A：試験は信頼できる　B：試験は条件付きで信頼できる　C：試験の信頼性は低い　D：信頼性の判定不可　E：信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり　Supplemental:条件付きで信頼性あり　Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり：○
なし：×		 情報源 情報源による
信頼性評価**		 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value		 exposure
duration
unit		 toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material		 original work type original work
reliability rank		 author title referenced journal publication year Information
update date
藻類 Pseudokirchneriella subcapitata Population NOEC 7 days 100000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) National Association of Photographic Manufacturers Environmental Effect of Photoprocessing Chemicals Vol I and II (557) EPA/OTS Doc. #40-8469216:536 p. 1974 2016/03/25
藻類 Pseudokirchneriella subcapitata growth rate EC50 96 hours 6500～13000 12 ECHA Information on Registered Substances 2 study report 1982 2016/02/26
藻類 Pseudokirchneriella subcapitata growth rate NOEC 72 hours >100 mg/L 12 ECHA Information on Registered Substances 2 OECD SIDS Ethylene Glycols Category, Apr 2004 OECD, Apr 2004 2004 2016/02/26
甲殻類 Daphnia magna Behavior EC50 1 days >10000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuehn Results of Toxic Action of Water Pollutants on Daphnia magna Straus Tested by an Improved Standardized Procedure Z. Wasser-Abwasser-Forsch.15(1): 1-6 1982 2016/03/25
甲殻類 Daphnia magna Mortality LC50 4 days 3700 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) National Association of Photographic Manufacturers Environmental Effect of Photoprocessing Chemicals Vol I and II (557) EPA/OTS Doc. #40-8469216:536 p. 1974 2016/03/25
甲殻類 Daphnia magna Mortality LC50 4 days 300～1000 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) National Association of Photographic Manufacturers Environmental Effect of Photoprocessing Chemicals Vol I and II (557) EPA/OTS Doc. #40-8469216:536 p. 1974 2016/03/25
甲殻類 Daphnia magna Mortality 1000～100000 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) National Association of Photographic Manufacturers Environmental Effect of Photoprocessing Chemicals Vol I and II (557) EPA/OTS Doc. #40-8469216:536 p. 1974 2016/03/25
甲殻類 Daphnia magna Physiology LC50 1 days >10000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuhn Results of the Damaging Effect of Water Pollutants on Daphnia magna (Befunde der Schadwirkung Wassergefahrdender Stoffe Gegen Daphnia magna) TR-79-1204, Literature Research Company, Annandale, VA:26 p. 1977 2016/03/25
甲殻類 Daphnia magna mobility EC100 24 hours >10000 mg/L × 12 ECHA Information on Registered Substances 2 Bringmann G, Kuehn R Ergebnisse der Schadwirkung wassergefaehrdender Stoffe gegen Daphnia magna in einem weiterentwickelten standardisierten Testverfahren Z Wasser Abwasser Forsch 1982 2016/02/26
甲殻類 Daphnia magna mobility EC50 24 hours >10000 mg/L × 12 ECHA Information on Registered Substances 2 Bringmann G, Kuehn R Ergebnisse der Schadwirkung wassergefaehrdender Stoffe gegen Daphnia magna in einem weiterentwickelten standardisierten Testverfahren Z Wasser Abwasser Forsch 1982 2016/02/26
甲殻類 Daphnia magna EC50 48 hours >100 mg/L 4 OECD SIDS (HPVC) Sewell IG and Wetton PM Diethylene glycol E:Diethylene glycol E: Acute toxicity to Daphnia magna. Project number 44/969 1994 2016/02/29
甲殻類 Daphnia magna LC50 48 hours >10000 mg/L 4 OECD SIDS (HPVC) Waggy, G.T., Blessing, R.L. and del Pino, M.P Ecological Fate and Effects Testing of UCC Products and Wastewaters During 1987 1988 2016/02/29
甲殻類 Daphnia magna EC50 48 hours >100 mg/L 4 OECD SIDS (HPVC) Dow Chemical Co 2016/02/29
甲殻類 Daphnia magna EC50 96 hours >100 mg/L 4 OECD SIDS (HPVC) National Association of Photographic Manufacturers, Inc 1974 2016/02/29
甲殻類 Daphnia magna LC50 24 hours >10000 mg/L 4 OECD SIDS (HPVC) Bringmann, G. and Kühn, R Z.Wasser- und Abwasser-Forschung 1977 2016/02/29
甲殻類 Daphnia magna EC50 48 hours 48900 mg/L 4 OECD SIDS (HPVC) 2 Blessing, RL Aquatic toxicity testing data on diethylene glycol UCC Project Report, File No. 44803 2000 2016/02/29
甲殻類 Daphnia magna LC50 48 hours >100 mg/L 4 OECD SIDS (HPVC) Sewell, IM, and Wetton, PM Diethylene glycol-E: acute toxicity to Daphnia magna DET report number 1921 1992 2016/02/29
甲殻類 Daphnia magna reproduction NOEC 28 days >=5500 μL/L × 12 ECHA Information on Registered Substances 2 LeBlanc GA and Surprenant DC The acute and chronic toxicity of acetone, dimethyl formamide and triethylene glycol to daphnia magna (Straus). Arch Environ Contam Toxicol 1983 2016/02/26
甲殻類 Daphnia magna reproduction and survival NOEC 21 days >15000 mg/L 12 ECHA Information on Registered Substances 2 publication 1985 2016/02/26
甲殻類 Daphnia magna reproduction EC50 21 days 33911 mg/L 12 ECHA Information on Registered Substances 2 publication 1985 2016/02/26
甲殻類 Daphnia magna growth NOEC 21 days 7500～15000 12 ECHA Information on Registered Substances 2 publication 1985 2016/02/26
甲殻類 Ceriodaphnia dubia reproduction NOEC 7 days 8590 mg/L 12 ECHA Information on Registered Substances 2 Pillard, D Comparative toxicity of formulated glycol deicers and pure ethylene and propylene glycol to Ceriodaphnia dubia and Pimephales promelas Environ. Toxicology and Chemistry 1995 2016/02/26
甲殻類 Ceriodaphnia dubia mortality NOEC 7 days 24000 mg/L 12 ECHA Information on Registered Substances 2 Pillard, D Comparative toxicity of formulated glycol deicers and pure ethylene and propylene glycol to Ceriodaphnia dubia and Pimephales promelas Environ. Toxicology and Chemistry 1995 2016/02/26
甲殻類 Daphnia magna NOEC 48 hours 36000 mg/L 4 OECD SIDS (HPVC) 2 Blessing, RL Aquatic toxicity testing data on diethylene glycol UCC Project Report, File No. 44803 2000 2016/02/29
甲殻類 Daphnia magna NOEC 48 hours >100 mg/L 4 OECD SIDS (HPVC) Sewell, IM, and Wetton, PM Diethylene glycol-E: acute toxicity to Daphnia magna DET report number 1921 1992 2016/02/29
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 75200000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Geiger,D.L., L.T. Brooke, and D.J. Call Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales promelas), Volume V Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI:332 p. 1990 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality LC0 4 days >1000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Buzzell,J.C.,Jr., R.H.F. Young, and D.W. Ryckman Behavior of Organic Chemicals in the Aquatic Environment. Part II. - Behavior in Dilute Systems Environ.Sanitary Engineering Labs., Washington University, St.Louis, MO:81 p. 1968 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days >100000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) National Association of Photographic Manufacturers Environmental Effect of Photoprocessing Chemicals Vol I and II (557) EPA/OTS Doc. #40-8469216:536 p. 1974 2016/03/25
魚類 Carassius auratus (Goldfish) Mortality LC50 1 days >5000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bridie,A.L., C.J.M. Wolff, and M. Winter The Acute Toxicity of Some Petrochemicals to Goldfish Water Res.13(7): 623-626 1979 2016/03/25
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 75200 mg/L × 12 ECHA Information on Registered Substances 2 study report 1990 2016/02/26
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours 77900 mg/L × 4 OECD SIDS (HPVC) 2 Blessing, RL Aquatic toxicity testing data on diethylene glycol UCC Project Report 2000 2016/02/29
魚類 Carassius auratus (Goldfish) LC50 24 hours >5000 mg/L 4 OECD SIDS (HPVC) Bridie, AL, Wolff, CJM, and Winter, M The acute toxicity of some petrochemicals to goldfish Water Research 1979 2016/02/29
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 96 hours 75100 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Russom, C.L., Bradbury, S.P., Broderius, S.J., Drummond, R.A. and Hammermeister, D.E. PREDICTING MODES OF TOXIC ACTION FROM CHEMICAL STRUCTURE: ACUTE TOXICITY IN THE FATHEAD MINNOW (PIMEPHALES PROMELAS) 1997 2016/02/08
魚類 Carassius auratus (Goldfish) Mortality LC50 24 hours 99000 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Lipnick, R.L., K.R. Watson, and A.K.Strausz A QSAR Study of the Acute Toxicity of Some Industrial Organic Chemicals to Goldfish. Narcosis, Electrophile and Proelectrophile Mechanisms. 1987 2016/02/08
魚類 Poecilia reticulata (Guppy) Mortality LC50 96 hours 61100 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Raevsky, O.A., and Dearden, J.C. Creation of predictive models of aquatic toxicity of environmental pollutants with different mechanisms of action on the basis of molecular similarity and hybot descriptors. 2004 2016/02/08
魚類 Pimephales promelas (Fathead minnow) mortality NOEC 7 days 32000 mg/L 12 ECHA Information on Registered Substances 2 Pillard, D Comparative toxicity of formulated glycol deicers and pure ethylene and propylene glycol to Ceriodaphnia dubia and Pimephales promelas Environ. Toxicology and Chemistry 1995 2016/02/26
魚類 Pimephales promelas (Fathead minnow) weight NOEC 7 days 15380 mg/L 12 ECHA Information on Registered Substances 2 Pillard, D Comparative toxicity of formulated glycol deicers and pure ethylene and propylene glycol to Ceriodaphnia dubia and Pimephales promelas Environ. Toxicology and Chemistry 1995 2016/02/26
魚類 Poecilia reticulata (Guppy) LC50 14 days 61 g/L × 4 OECD SIDS (HPVC) 2 Konemann, H Quantitative structure-activity relationships in fish toxicity studies. Part 1: relationship for 50 industrial chemicals Toxicology 1981 2016/02/29
魚類 Pimephales promelas (Fathead minnow) NOEC 96 hours 49000 mg/L × 4 OECD SIDS (HPVC) 2 Blessing, RL Aquatic toxicity testing data on diethylene glycol UCC Project Report 2000 2016/02/29