生態影響に係る有害性情報


CAS登録番号 CAS RN ® ： 121-69-7
官報公示整理番号　METI No. ： 3-114/3-129
物質名 test material ： Ｎ，Ｎ－ジメチルアニリン　／Benzenamine, N,N-dimethyl-
水溶解度 water solubility ： 1450mg/L (推計値 estimated)
LogKow ： 2.31 (実測値 measured)
備考 remarks ：
Excelファイルダウンロード

【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書） / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし　4:情報が少なく評価不能
日本環境省　化学物質の環境リスク評価（生態リスク初期評価） A：試験は信頼できる　B：試験は条件付きで信頼できる　C：試験の信頼性は低い　D：信頼性の判定不可　E：信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり　Supplemental:条件付きで信頼性あり　Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり：○
なし：×		 情報源 情報源による
信頼性評価**		 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value		 exposure
duration
unit		 toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material		 original work type original work
reliability rank		 author title referenced journal publication year Information
update date
藻類 Chlorella pyrenoidosa Population/Population growth rate EC50 72 hours 22000 μg/L × 16 ECOTOX Ramos,E.U., W.H.J. Vaes, P. Mayer, and J.L.M. Hermens Algal Growth Inhibition of Chlorella pyrenoidosa by Polar Narcotic Pollutants: Toxic Cell Concentrations and QSAR Modeling Aquat. Toxicol.46(1) 2020/11/12
藻類 Scenedesmus subspicatus EC50 96 hours 340 mg/L 19 その他 BASF AG, Labor Oekologie unveroeffentlichte Untersuchung, (1020/88) 2021/04/21
藻類 Pseudokirchneriella subcapitata Population/Population growth rate EC50 48 hours 37 mg/L × 16 ECOTOX Kusk,K.O., A.M. Christensen, and N. Nyholm Algal Growth Inhibition Test Results of 425 Organic Chemical Substances Chemosphere204 2020/11/12
藻類 Chlorella pyrenoidosa growth rate EC50 72 hours 22 mg/L 12 ECHA Information on Registered Substances Ramos, E.U., W.H.J. Vaes, P. Mayer, and J.L.M. Hermens Algal Growth Inhibition of Chlorella pyrenoidosa by Polar Narcotic Pollutants: Toxic Cell Concentrations and QSAR Modeling Aquatic Toxicology Volume 46, Issue 1 2021/03/02
藻類 Chlorella pyrenoidosa growth rate LOEC 72 hours 22 mg/L 12 ECHA Information on Registered Substances Eñaut Urrestarazu Ramos, Wouter H.J Vaes, Philipp Mayer, Joop L.M Hermens Algal growth inhibition of Chlorella pyrenoidosa by polar narcotic pollutants: toxic cell concentrations and QSAR modeling Aquatic Toxicology Volume 46, Issue 1 2021/03/02
藻類 Chlorella pyrenoidosa growth rate NOEC 72 hours 14 mg/L 12 ECHA Information on Registered Substances Eñaut Urrestarazu Ramos, Wouter H.J Vaes, Philipp Mayer, Joop L.M Hermens Algal growth inhibition of Chlorella pyrenoidosa by polar narcotic pollutants: toxic cell concentrations and QSAR modeling Aquatic Toxicology Volume 46, Issue 1 2021/03/02
藻類 Agmenellum quadruplicatum growth rate NOEC 0.1～1000 μg/disk meas. not specified 12 ECHA Information on Registered Substances CESARS database Record No.: 209 CESARS (Chemical Evaluation Search and Retrieval System ); Michigan Department of Environmental Quality and Ontario Ministry of the Environment 2021/03/02
藻類 Chlorella pyrenoidosa growth rate EC10 72 hours 13 mg/L 9 ECETOC Aquatic Toxicity, EAT Urrestarazu Ramos E, Vaes WHJ, Mayer P, Hermens JLM Algal growth inhibition of Chlorella pyrenoidosa by polar narcotic pollutants: toxic cell concentrations and QSAR modelling Aquat Toxicol 46 2020/12/23
藻類 Chlorella pyrenoidosa growth rate NOEC 72 hours 14 mg/L 9 ECETOC Aquatic Toxicity, EAT Urrestarazu Ramos E, Vaes WHJ, Mayer P, Hermens JLM Algal growth inhibition of Chlorella pyrenoidosa by polar narcotic pollutants: toxic cell concentrations and QSAR modelling Aquat Toxicol 46 2020/12/23
藻類 Chlorella pyrenoidosa growth rate EC20 72 hours 22 mg/L 9 ECETOC Aquatic Toxicity, EAT Urrestarazu Ramos E, Vaes WHJ, Mayer P, Hermens JLM Algal growth inhibition of Chlorella pyrenoidosa by polar narcotic pollutants: toxic cell concentrations and QSAR modelling Aquat Toxicol 46 2020/12/23
藻類 Chlorella pyrenoidosa Population/Population growth rate LOEC 72 hours 22000 μg/L × 16 ECOTOX Ramos,E.U., W.H.J. Vaes, P. Mayer, and J.L.M. Hermens Algal Growth Inhibition of Chlorella pyrenoidosa by Polar Narcotic Pollutants: Toxic Cell Concentrations and QSAR Modeling Aquat. Toxicol.46(1) 2020/11/12
藻類 Chlorella pyrenoidosa Population/Population growth rate NOEC 72 hours 14000 μg/L × 16 ECOTOX Ramos,E.U., W.H.J. Vaes, P. Mayer, and J.L.M. Hermens Algal Growth Inhibition of Chlorella pyrenoidosa by Polar Narcotic Pollutants: Toxic Cell Concentrations and QSAR Modeling Aquat. Toxicol.46(1) 2020/11/12
藻類 Pseudokirchneriella subcapitata Population/Population growth rate EC10 48 hours 32 mg/L × 16 ECOTOX Kusk,K.O., A.M. Christensen, and N. Nyholm Algal Growth Inhibition Test Results of 425 Organic Chemical Substances Chemosphere204 2020/11/12
藻類 Scenedesmus subspicatus EC10 96 hours 210 mg/L 19 その他 BASF AG, Labor Oekologie unveroeffentlichte Untersuchung, (1020/88) 2021/05/14
藻類 Chlorella pyrenoidosa cell number NOEC 72 hours 14 mg/L 12 ECHA Information on Registered Substances Ramos, E.U., W.H.J. Vaes, P. Mayer, and J.L.M. Hermens Reference Number : 14484 ECOTOX (ECOTOXicology database);Algal Growth Inhibition of Chlorella pyrenoidosa by Polar Narcotic Pollutants 2021/03/02
藻類 Chlorella pyrenoidosa not specified NO(A)EC 72 hours 14 mg/L 12 ECHA Information on Registered Substances Vaes, Ramos, Enaut Urrestarazu;Wouter H. J.; Mayer, Philipp; Hermens, Joop L. M QSAR for CAS No. 121-69-7 2021/03/02
藻類 Chlorella pyrenoidosa not specified LO(A)EC 72 hours 22 mg/L 12 ECHA Information on Registered Substances Vaes, Ramos, Enaut Urrestarazu;Wouter H. J.; Mayer, Philipp; Hermens, Joop L. M QSAR for CAS No. 121-69-7 2021/03/02
甲殻類 Daphnia magna Swimming ability EC100 24 hours 40 mg/L 14 BUA Report BASF AG Bestimmung der Ökotoxizität. Unveröffentlichte Untersuchung 2021/02/09
甲殻類 Daphnia magna Swimming ability EC50 48 hours 5 mg/L 14 BUA Report BASF AG Bestimmung der Ökotoxizität. Unveröffentlichte Untersuchung 2021/02/09
甲殻類 Daphnia magna Swimming ability EC0 48 hours 0.8 mg/L 14 BUA Report BASF AG Bestimmung der Ökotoxizität. Unveröffentlichte Untersuchung 2021/02/09
甲殻類 Daphnia magna Swimming ability EC50 24 hours 13 mg/L 14 BUA Report BASF AG Bestimmung der Ökotoxizität. Unveröffentlichte Untersuchung 2021/02/09
甲殻類 Daphnia magna Swimming ability EC0 24 hours 8 mg/L 14 BUA Report BASF AG Bestimmung der Ökotoxizität. Unveröffentlichte Untersuchung 2021/02/09
甲殻類 Daphnia magna Swimming ability EC100 48 hours 20 mg/L 14 BUA Report BASF AG Bestimmung der Ökotoxizität. Unveröffentlichte Untersuchung 2021/02/09
甲殻類 Daphnia magna Intoxication EC50 48 hours 1.7～3.1 mg/L 12 ECHA Information on Registered Substances Pedersen, F., E. Bjornestad, T. Vulpius, and H.B. Rasmussen No information ECOTOX (ECOTOXicology database);Immobilisation Test of Aniline Compounds with the Crustacean Daphnia magna;Proj.No.303587, Report to the Danish EPA, Copenhagen, Denmark 2021/03/02
甲殻類 Daphnia magna EC100 48 hours 20 mg/L 19 その他 BASF AG, Labor Oekologie unveroeffentlichte Untersuchung, (1020/88) 2021/04/21
甲殻類 Daphnia magna EC0 24 hours 8 mg/L 19 その他 BASF AG, Labor Oekologie unveroeffentlichte Untersuchung, (1020/88) 2021/04/21
甲殻類 Daphnia magna EC0 48 hours 0.8 mg/L 14 BUA Report BASF AG Ecology Laboratory; unpublished study, (1020/88). 2021/04/06
甲殻類 Daphnia magna EC0 24 hours 8 mg/L 14 BUA Report BASF AG Ecology Laboratory; unpublished study, (1020/88). 2021/04/06
甲殻類 Daphnia magna EC50 48 hours 5 mg/L 19 その他 BASF AG, Labor Oekologie unveroeffentlichte Untersuchung, (1020/88) 2021/04/21
甲殻類 Daphnia magna EC100 24 hours 40 mg/L 19 その他 BASF AG, Labor Oekologie unveroeffentlichte Untersuchung, (1020/88) 2021/04/21
甲殻類 Daphnia magna EC100 24 hours 40 mg/L 14 BUA Report BASF AG Ecology Laboratory; unpublished study, (1020/88). 2021/04/06
甲殻類 Daphnia magna EC50 48 hours 15 mg/L 14 BUA Report BASF AG Ecology Laboratory; unpublished study, (1020/88). 2021/04/06
甲殻類 Daphnia magna EC50 24 hours 13 mg/L 14 BUA Report BASF AG Ecology Laboratory; unpublished study, (1020/88). 2021/04/06
甲殻類 Daphnia magna EC100 48 hours 20 mg/L 14 BUA Report BASF AG Ecology Laboratory; unpublished study, (1020/88). 2021/04/06
甲殻類 Daphnia magna EC50 24 hours 13 mg/L 19 その他 BASF AG, Labor Oekologie unveroeffentlichte Untersuchung, (1020/88) 2021/04/21
甲殻類 Daphnia magna EC0 48 hours 0.8 mg/L 19 その他 BASF AG, Labor Oekologie unveroeffentlichte Untersuchung, (1020/88) 2021/04/21
甲殻類 Daphnia magna Intoxication/Immobile EC50 48 hours 2.3 mg/L ○ 16 ECOTOX Pedersen,F., E. Bjornestad, T. Vulpius, and H.B. Rasmussen Immobilisation Test of Aniline Compounds with the Crustacean Daphnia magna Proj.No.303587, Report to the Danish EPA, Copenhagen, Denmark 2020/11/12
甲殻類 Daphnia magna Intoxication/Immobile EC50 48 hours 13700 μg/L × 16 ECOTOX Ramos,E.U., C. Vermeer, W.H.J. Vaes, and J.L.M. Hermens Acute Toxicity of Polar Narcotics to Three Aquatic Species (Daphnia magna, Poecilia reticulata and Lymnaea stagnalis) and Its Relation to Hydrophobicity Chemosphere37(4) 2020/11/12
甲殻類 Daphnia magna Intoxication/Immobile EC50 24 hours 5.8 mg/L ○ 16 ECOTOX Pedersen,F., E. Bjornestad, T. Vulpius, and H.B. Rasmussen Immobilisation Test of Aniline Compounds with the Crustacean Daphnia magna Proj.No.303587, Report to the Danish EPA, Copenhagen, Denmark 2020/11/12
甲殻類 Daphnia sp. Intoxication/Immobile EC50 24 hours 16500 μg/L × 16 ECOTOX Tosato,M.L., A. Pino, L. Passerini, S. Marchini, L. Vigano, and D. Hoglund Updating and Validation of a Daphnia Toxicity Model for Benzene Derivatives Sci. Total Environ.Suppl.(Pts.1/2) 2020/11/12
甲殻類 Daphnia magna mobility EC50 24 hours 5.8 mg/L 12 ECHA Information on Registered Substances ECOTOXicology database Reference Number: 55961 ECOTOX (ECOTOXicology database) 2021/03/02
甲殻類 Daphnia magna Intoxication/Immobile EC50 24 hours 29700 μg/L × 16 ECOTOX Ramos,E.U., C. Vermeer, W.H.J. Vaes, and J.L.M. Hermens Acute Toxicity of Polar Narcotics to Three Aquatic Species (Daphnia magna, Poecilia reticulata and Lymnaea stagnalis) and Its Relation to Hydrophobicity Chemosphere37(4) 2020/11/12
甲殻類 Daphnia magna Intoxication EC50 24 hours 4.4～8.1 mg/L 12 ECHA Information on Registered Substances Pedersen, F., E. Bjornestad, T. Vulpius, and H.B. Rasmussen No information ECOTOX (ECOTOXicology database);Immobilisation Test of Aniline Compounds with the Crustacean Daphnia magna Proj.No.303587, Report to the Danish EPA, Copenhagen, Denmark 2021/03/02
甲殻類 Daphnia magna mobility EC50 48 hours 2.3 mg/L 12 ECHA Information on Registered Substances Pedersen, F., E. Bjornestad, T. Vulpius, and H.B. Rasmussen Immobilisation Test of Aniline Compounds with the Crustacean Daphnia magna; Proj.No.303587, Report to the Danish EPA, Copenhagen, Denmark 2021/03/02
甲殻類 Daphnia magna mobility EC50 48 hours 13.7 mg/L 12 ECHA Information on Registered Substances Ramos, E.U. et. al.; Acute Toxicity of Polar Narcotics to Three Aquatic Species (Daphnia magna, Poecilia reticulata and Lymnaea stagnalis) and Its Relation to Hydrophobicity Chemosphere; 37 (4) 2021/03/02
甲殻類 Daphnia magna Intoxication EC50 48 hours 11.2～16.8 mg/L 12 ECHA Information on Registered Substances Ramos, E.U., C. Vermeer, W.H.J. Vaes, and J.L.M. Hermens No information ECOTOX (ECOTOXicology database);Acute Toxicity of Polar Narcotics to Three Aquatic Species (Daphnia magna, Poecilia reticulata and Lymnaea stagnalis) and Its Relation to Hydrophobicity;Chemosphere37(4) 2021/03/02
魚類 Cyprinus carpio (Carp) Bioconcentration 6 weeks Method: Test method is stipulated in the Japanese Order Prescribing the Items of the Test Relating to the New Chemical Substances (1974). This guideline corresponds to OECD Guideline for Testing Chemicals No.305C (May 12, 1981). Two nominal concentrations of the compound were used for 6 weeks: = 0.5 and 0.05 mg/l. Bioconcentration factors established were 5.4-13.6 and 4.7-10.1, respectively. × 14 BUA Report 2021/03/16
魚類 Danio rerio (Zebrafish) Mortality/Mortality LC50 96 hours 1.51 μmol/L × 16 ECOTOX Groth,G., K. Schreeb, V. Herdt, and K.J. Freundt Toxicity Studies in Fertilized Zebrafish Eggs Treated with N-Methylamine, N,N,-Dimethylamine, 2-Aminoethanol, Isopropylamine, Aniline, N-Methylaniline Bull. Environ. Contam. Toxicol.50 2020/11/12
魚類 Danio rerio (Zebrafish) Development/Developmental changes, general NOEC 96 hours 0.33 μmol/L × 16 ECOTOX Groth,G., K. Schreeb, V. Herdt, and K.J. Freundt Toxicity Studies in Fertilized Zebrafish Eggs Treated with N-Methylamine, N,N,-Dimethylamine, 2-Aminoethanol, Isopropylamine, Aniline, N-Methylaniline Bull. Environ. Contam. Toxicol.50 2020/11/12
魚類 Pimephales promelas Mortality LC50 96 hours 78.2 mg/L 14 BUA Report Brooke, L.T., Call, D.J., Geiger, D.L., Northcott, C.E. Acute toxicities of organic chemicals to fathead minnows (Pimephales promelas) Center for Lake Superior Environmental Studies, University of Wisconsin-Superior, USA 2021/04/06
魚類 Poecilia reticulata (Guppy) mortality LC50 72 hours 53.7 mg/L 9 ECETOC Aquatic Toxicity, EAT Urrestarazu Ramos E, Vermeer C, Vaes WHJ, Hermens JLM Acute toxicity of polar narcotics to three aquatic species (Daphnia magna, Poecilia reticulata and Lymnaea stagnalis) and its relation to hydrophobicity Chemosphere 37 2020/12/23
魚類 Carassius auratus (Goldfish) Mortality LC50 48 hours 69 mg/L 14 BUA Report Tonogai, Y., Ogawa, S., Ito, Y., Iwaida, M. Studies of the syncopic effect of aniline derivatives in fish. 1. The problem concerning the determination of median lethal concentration in fish. Eisei Kagaku, 29 2021/03/16
魚類 Pimephales promelas Hypoactivity, swimming at the surface or lateral position EC50 96 hours 52.6 mg/L 14 BUA Report Brooke, L.T., Call, D.J., Geiger, D.L., Northcott, C.E. Acute toxicities of organic chemicals to fathead minnows (Pimephales promelas) Center for Lake Superior Environmental Studies, University of Wisconsin-Superior, USA 2021/04/06
魚類 Pimephales promelas Mortality LC50 96 hours 52.6 mg/L 14 BUA Report Brooke, L.T., Call, D.J., Geiger, D.L., Northcott, C.E. Acute toxicities of organic chemicals to fathead minnows (Pimephales promelas) Center for Lake Superior Environmental Studies, University of Wisconsin-Superior, USA 2021/04/06
魚類 Pimephales promelas Mortality LC50 96 hours 65.6 mg/L 14 BUA Report Broderius, S., Kahl, M. Acute toxicity of organic chemical mixtures to the fathead minnow. Aquat. Toxicol. 6 2021/02/09
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 48 hours 76 mg/L 14 BUA Report Yoshioka, Y., Ose, Y., Sato, T. Testing and evaluation of chemical toxicity on Tubifex. Eisei Kagaku 32 2021/03/16
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 48 hours 98 mg/L 14 BUA Report Tonogai, Y., Ogawa, S., Ito, Y., Iwaida, M. Studies of the syncopic effect of aniline derivatives in fish. 1. The problem concerning the determination of median lethal concentration in fish. Eisei Kagaku 29 2021/03/16
魚類 Oryzias latipes (Japanese medaka) Lateral position and narcotization EC50 48 hours 64 mg/L 14 BUA Report Tonogai, Y., Ogawa, S., Ito, Y., Iwaida, M. Studies of the syncopic effect of aniline derivatives in fish. 1. The problem concerning the determination of median lethal concentration in fish. Eisei Kagaku 29 2021/03/16
魚類 Carassius auratus (Goldfish) Lateral position and narcotization EC50 48 hours 56 mg/L 14 BUA Report Tonogai, Y., Ogawa, S., Ito, Y., Iwaida, M. Studies of the syncopic effect of aniline derivatives in fish. 1. The problem concerning the determination of median lethal concentration in fish. Eisei Kagaku, 29 2021/03/16
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 48 hours 78 mg/L 14 BUA Report Tonogai, Y., Ogawa, S., Ito, Y., Iwaida, M. Studies of the syncopic effect of aniline derivatives in fish. 1. The problem concerning the determination of median lethal concentration in fish. Eisei Kagaku 29 2021/03/16
魚類 Pimephales promelas Hypoactivity, swimming at the surface or lateral position EC50 96 hours 75.2 mg/L 14 BUA Report Brooke, L.T., Call, D.J., Geiger, D.L., Northcott, C.E. Acute toxicities of organic chemicals to fathead minnows (Pimephales promelas) Center for Lake Superior Environmental Studies, University of Wisconsin-Superior, USA 2021/04/06
魚類 Cyprinus carpio (Carp) Lateral position and narcotization EC50 48 hours 57 mg/L 14 BUA Report Tonogai, Y., Ogawa, S., Ito, Y., Iwaida, M. Studies of the syncopic effect of aniline derivatives in fish. 1. The problem concerning the determination of median lethal concentration in fish. Eisei Kagaku, 29 2021/03/16
魚類 Oryzias latipes (Japanese medaka) 50 % of the test organisms survive. TLm 24 hours 56 mg/L 14 BUA Report Tonogai, Y., Ogawa, S., Ito, Y., Iwaida, M. Actual survey of TLm (Median Tolerance Limit) values of environmental pollutants, especially on amines, nitrites, aromatic nitrogen compounds and artificial dyes. J. Toxicol. Sci. 7 2021/03/16
魚類 Carassius auratus (Goldfish) Mortality LC50 48 hours 69 mg/L × × 14 BUA Report Tonogai Y, Ogawa S, Ito Y and Iwaida M Studies of the syncopic effect of aniline derivatives on fish. The problem concerning the determination of median lethal concentration in fish. Eisei Kagaku, 29 2021/02/10
魚類 Oryzias latipes (Japanese medaka) 50 % of the test organisms survive. TLm 48 hours 33 mg/L 14 BUA Report Tonogai, Y., Ogawa, S., Ito, Y., Iwaida, M. Actual survey of TLm (Median Tolerance Limit) values of environmental pollutants, especially on amines, nitrites, aromatic nitrogen compounds and artificial dyes. J. Toxicol. Sci. 7 2021/03/16
魚類 Cyprinus carpio (Carp) Mortality LC50 48 hours 69 mg/L 14 BUA Report Tonogai, Y., Ogawa, S., Ito, Y., Iwaida, M. Studies of the syncopic effect of aniline derivatives in fish. 1. The problem concerning the determination of median lethal concentration in fish. Eisei Kagaku, 29 2021/03/16
魚類 Carassius auratus (Goldfish) behaviour EC50 48 hours 56 mg/L 12 ECHA Information on Registered Substances Tonogai, Y., S. Ogawa, Y. Ito, and M. Iwaida Reference Number : 10786 ECOTOX (ECOTOXicology database);Studies of the Syncopic Effect of Aniline Derivatives on Fish. I. The Problem Concerning the Determination of Median Lethal Concentration 2021/03/02
魚類 Pimephales promelas mortality EC50 96 hours 75.2 mg/L 12 ECHA Information on Registered Substances GCID : 42825 ACToR;Brooke, L.T., D.J. Call et al.; Acute Toxicities of Organic Chemicals to(Pimephales Promelas). Superior, WI 2021/03/02
魚類 Pimephales promelas mortality LC50 96 hours 78.2 mg/L 12 ECHA Information on Registered Substances Brooke, L.T., D.J. Call, D.T. Geiger et.al.; Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales Promelas). Superior, WI 2021/03/02
魚類 Oryzias latipes (Japanese medaka) mortality LC50 48 hours 33 mg/L 12 ECHA Information on Registered Substances Tonogai, Y., S. Ogawa, Y. Ito, and M. Iwaida Actual Survey on TLM (Median Tolerance Limit) Values of Environmental Pollutants, Especially on Amines, Nitriles, Aromatic Nitrogen Compounds and Artificial Dyes The Journal of Toxicological Sciences; 7(3) 2021/03/02
魚類 Carassius auratus (Goldfish) behaviour EC50 48 hours 56 mg/L 12 ECHA Information on Registered Substances ECOTOXicology database Reference Number: 10786 ECOTOX (ECOTOXicology database) 2021/03/02
魚類 Poecilia reticulata (Guppy) mortality LC50 24 hours 55.4 mg/L 9 ECETOC Aquatic Toxicity, EAT Urrestarazu Ramos E, Vermeer C, Vaes WHJ, Hermens JLM Acute toxicity of polar narcotics to three aquatic species (Daphnia magna, Poecilia reticulata and Lymnaea stagnalis) and its relation to hydrophobicity Chemosphere 37 2020/12/23
魚類 Poecilia reticulata (Guppy) mortality LC50 96 hours 53.7 mg/L 9 ECETOC Aquatic Toxicity, EAT Urrestarazu Ramos E, Vermeer C, Vaes WHJ, Hermens JLM Acute toxicity of polar narcotics to three aquatic species (Daphnia magna, Poecilia reticulata and Lymnaea stagnalis) and its relation to hydrophobicity Chemosphere 37 2020/12/23
魚類 Poecilia reticulata (Guppy) mortality LC50 48 hours 53.7 mg/L 9 ECETOC Aquatic Toxicity, EAT Urrestarazu Ramos E, Vermeer C, Vaes WHJ, Hermens JLM Acute toxicity of polar narcotics to three aquatic species (Daphnia magna, Poecilia reticulata and Lymnaea stagnalis) and its relation to hydrophobicity Chemosphere 37 2020/12/23
魚類 Oryzias latipes (Japanese medaka) LC50 48 hours 98 mg/L 19 その他 Tonogai Y. et al. Studies of the syncopic effect of aniline derivatives on fish. The problem concerning the determination of median lethal concentration in fish. Eisei Kagaku, 29 (5), zitiert im BUA-Stoffbericht, (Entwurf 1992) 2021/04/21
魚類 Danio rerio (Zebrafish) Mortality LC50 96 hours >=0.183～<=0.186 mg/L × × 14 BUA Report Groth, G., Schreeb, K., Herdt, V., & K. J. Freundt, K. J. Toxicity studies in fertilized zebrafish eggs treated with N-methylamine, N,N-dimethylamine, 2-aminoethanol, isopropylamine, aniline, N-methylaniline, N,N-dimethylaniline, quinone, chloroacetaldehyde, or cyclohexanol Bull. Environ. Contam. Toxicol. 50 2021/03/16
魚類 Danio rerio (Zebrafish) Mortality LC100 96 hours 0.242 mg/L × × 14 BUA Report Groth, G., Schreeb, K., Herdt, V., & K. J. Freundt, K. J. Toxicity studies in fertilized zebrafish eggs treated with N-methylamine, N,N-dimethylamine, 2-aminoethanol, isopropylamine, aniline, N-methylaniline, N,N-dimethylaniline, quinone, chloroacetaldehyde, or cyclohexanol Bull. Environ. Contam. Toxicol. 50 2021/03/16
魚類 Poecilia reticulata (Guppy) Mortality/Mortality LC50 48 hours 53700 μg/L ○ 16 ECOTOX Ramos,E.U., C. Vermeer, W.H.J. Vaes, and J.L.M. Hermens Acute Toxicity of Polar Narcotics to Three Aquatic Species (Daphnia magna, Poecilia reticulata and Lymnaea stagnalis) and Its Relation to Hydrophobicity Chemosphere37(4) 2020/11/12
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours 65.6 mg/L × ○ 19 その他 Broderius S. and Kahl M. Acute toxicity of organic chemical mixtures to the fathead minnow Aquatic Toxicology, 6 (4) 2021/04/21
魚類 Carassius auratus (Goldfish) LC50 48 hours 69 mg/L × × 19 その他 Tonogai Y. et al. Studies of the syncopic effect of aniline derivatives on fish. The problem concerning the determination of median lethal concentration in fish. Eisei Kagaku (J. Hygienic Chemistry), 29 (5) 2021/04/21
魚類 Oryzias latipes (Japanese medaka) LC50 48 hours 98 mg/L × × 19 その他 Tonogai Y. et al. Studies of the syncopic effect of aniline derivatives on fish. The problem concerning the determination of median lethal concentration in fish. Eisei Kagaku (J. Hygienic Chemistry), 29 (5) 2021/04/21
魚類 Oryzias latipes (Japanese medaka) Mortality/Mortality LC50 24 hours 56000 μg/L × 16 ECOTOX Tonogai,Y., S. Ogawa, Y. Ito, and M. Iwaida Actual Survey on TLM (Median Tolerance Limit) Values of Environmental Pollutants, Especially on Amines, Nitriles, Aromatic Nitrogen Compounds J. Toxicol. Sci.7(3) 2020/11/12
魚類 Carassius auratus (Goldfish) Mortality/Mortality LC50 48 hours 69000 μg/L × 16 ECOTOX Tonogai,Y., S. Ogawa, Y. Ito, and M. Iwaida Studies of the Syncopic Effect of Aniline Derivatives on Fish. I. The Problem Concerning the Determination of Median Lethal Concentration Jpn. J. Toxicol. Environ. Health29(5) 2020/11/12
魚類 Cyprinus sp. Mortality LC50 48 hours 69 mg/L × × 14 BUA Report Tonogai Y, Ogawa S, Ito Y and Iwaida M Studies of the syncopic effect of aniline derivatives on fish. The problem concerning the determination of median lethal concentration in fish. Eisei Kagaku, 29 2021/02/10
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours 78.2 mg/L 19 その他 Brooke T.L. et al. Acute toxicities of organic chemicals to fathead minnows (Pimephales promelas) Center for Lake Superior Environmental Studies, University of Wisconsin-Superior, USA, zitiert im BUA-Stoffbericht (Entwurf 1992) 2021/04/21
魚類 Danio rerio (Zebrafish) Mortality NOEC 96 hours 0.039 mg/L × × 14 BUA Report Groth, G., Schreeb, K., Herdt, V., & K. J. Freundt, K. J. Toxicity studies in fertilized zebrafish eggs treated with N-methylamine, N,N-dimethylamine, 2-aminoethanol, isopropylamine, aniline, N-methylaniline, N,N-dimethylaniline, quinone, chloroacetaldehyde, or cyclohexanol Bull. Environ. Contam. Toxicol. 50 2021/03/16
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 48 hours 78 mg/L × × 14 BUA Report Tonogai, Y., Ogawa, S., Ito, Y. and Iwaida, M. Studies of the syncopic effect of aniline derivatives on fish. The problem concerning the determination of median lethal concentration in fish. Eisei Kagaku, 29 2021/03/16
魚類 Pimephales promelas Mortality LC50 96 hours 65.6 mg/L × ○ 14 BUA Report Broderius, S., and Kahl, M. Acute toxicity of organic chemical mixtures to the fathead minnow Aquatic Toxic. 6 2021/05/18
魚類 Oryzias latipes (Japanese medaka) TLm 48 hours 33 mg/L × × 19 その他 Tonogai Y. et al. Actual survey on TLm (median tolerance limit) values of environmental pollutants, especially on amines, nitriles, aromatic nitrogen compounds and artificial dyes. J. Toxicol Sci., 7 (3) 2021/04/21
魚類 Oryzias latipes (Japanese medaka) TLm 24 hours 56 mg/L × × 19 その他 Tonogai Y. et al. Actual survey on TLm (median tolerance limit) values of environmental pollutants, especially on amines, nitriles, aromatic nitrogen compounds and artificial dyes. J. Toxicol Sci., 7 (3) 2021/04/21
魚類 Oryzias latipes (Japanese medaka) SC50 48 hours 64 mg/L × × 19 その他 Tonogai Y. et al. Studies of the syncopic effect of aniline derivatives on fish. The problem concerning the determination of median lethal concentration in fish. Eisei Kagaku (J. Hygienic Chemistry), 29 (5) 2021/04/21
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours 78 mg/L × 19 その他 Schultz W.T. et al. QSARs for selected aliphatic and aromatic amines. Sci. Total Environ. 109/110 2021/04/21
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours 52.6 mg/L 19 その他 Brooke T.L. et al. Acute toxicities of organic chemicals to fathead minnows (Pimephales promelas) Center for Lake Superior Environmental Studies, University of Wisconsin-Superior, USA, zitiert im BUA-Stoffbericht (Entwurf 1992) 2021/04/21
魚類 Oryzias latipes (Japanese medaka) LC50 48 hours 102 mg/L × 19 その他 Chemicals Inspection & Testing Institute, Japan. Biodegradation and bioaccumulation data of existing chemicals based on the CSCL Japan. October 1992 2021/04/21
魚類 Carassius auratus (Goldfish) SC50 48 hours 56 mg/L × × 19 その他 Tonogai Y. et al. Studies of the syncopic effect of aniline derivatives on fish. The problem concerning the determination of median lethal concentration in fish. Eisei Kagaku (J. Hygienic Chemistry), 29 (5) 2021/04/21
魚類 Cyprinus carpio (Carp) 72 hours No effects were observed at doses of 80, 97 and 136 mg/kg within the 72-hour observation period. × × 14 BUA Report Loeb, H.A. and Kelly, W.H. U.S. Dept. of the Interior, Special Scientific Report - Fisheries No. 471, Washington D.C. 2021/03/16
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 48 hours 102 mg/L × × 14 BUA Report Chemicals Inspection & Testing Institute, Japan Biodegradation and bioaccumulation data of existing chemicals based on the CSCL Japan, October 1992 2021/03/16
魚類 Carassius auratus (Goldfish) Behavior/Equilibrium EC50 48 hours 56000 μg/L × 16 ECOTOX Tonogai,Y., S. Ogawa, Y. Ito, and M. Iwaida Studies of the Syncopic Effect of Aniline Derivatives on Fish. I. The Problem Concerning the Determination of Median Lethal Concentration Jpn. J. Toxicol. Environ. Health29(5) 2020/11/12
魚類 Brachydanio rerio (Zebrafish) LC50 96 hours 0.183～0.186 mg/L × × 19 その他 Groth G. et al. Toxicity Studies in Fertilized Zebrafish Eggs Treated with N-Methylamine, N,N-Dimethylamine, 2-Aminoethanol, Isopropylamine, Aniline, N-Methylaniline, N,N-Dimethylaniline, Quinone, Chloroacetaldehyde, or Cyclohexanol. Bull Environ. Contam. Toxicol. 50 (6) 2021/04/21
魚類 Pimephales promelas Mortality/Mortality LC50 96 hours 52600 μg/L ○ 16 ECOTOX Brooke,L.T., D.J. Call, D.L. Geiger, and C.E. Northcott Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales promelas), Vol. 1 Center for Lake Superior Environmental Studies, University of Wisconsin-Superior, Superior, WI 2020/11/12
魚類 Pimephales promelas Mortality/Mortality LC50 96 hours 78200 μg/L ○ 16 ECOTOX Brooke,L.T., D.J. Call, D.L. Geiger, and C.E. Northcott Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales promelas), Vol. 1 Center for Lake Superior Environmental Studies, University of Wisconsin-Superior, Superior, WI 2020/11/12
魚類 Oryzias latipes (Japanese medaka) Mortality TLm 48 hours 33 mg/L × × 14 BUA Report EPA Report No. EPA/600/X-87/052, November 1986 2021/03/16
魚類 Pimephales promelas Mortality/Mortality LC50 96 hours 65600 μg/L 16 ECOTOX Broderius,S., and M. Kahl Acute Toxicity of Organic Chemical Mixtures to the Fathead Minnow Aquat. Toxicol.6 2020/11/12
魚類 Oryzias latipes (Japanese medaka) Mortality TLm 24 hours 56 mg/L × × 14 BUA Report EPA Report No. EPA/600/X-87/052, November 1986 2021/03/16
魚類 Cyprinus carpio (Carp) LC50 48 hours 69 mg/L 19 その他 Tonogai Y. et al. Studies of the syncopic effect of aniline derivatives on fish. The problem concerning the determination of median lethal concentration in fish. Eisei Kagaku, 29 (5) 2021/04/21
魚類 Pimephales promelas Mortality LC50 96 hours 78 mg/L × × 14 BUA Report Schultz,T.W., Wilke,T.S., Bryant, S.E., Hosein, L.M. QSARs for selected aliphatic and aromatic amines. The Science of the Total Environment, 109-110 2021/05/18
魚類 Brachydanio rerio (Zebrafish) LC100 96 hours 0.242 mg/L × × 19 その他 Groth G. et al. Toxicity Studies in Fertilized Zebrafish Eggs Treated with N-Methylamine, N,N-Dimethylamine, 2-Aminoethanol, Isopropylamine, Aniline, N-Methylaniline, N,N-Dimethylaniline, Quinone, Chloroacetaldehyde, or Cyclohexanol. Bull Environ. Contam. Toxicol. 50 (6) 2021/04/21
魚類 Oryzias latipes (Japanese medaka) LC50 48 hours 78 mg/L 19 その他 Tonogai Y. et al. Studies of the syncopic effect of aniline derivatives on fish. The problem concerning the determination of median lethal concentration in fish. Eisei Kagaku, 29 (5), zitiert im BUA-Stoffbericht, (Entwurf 1992) 2021/04/21
魚類 Oryzias latipes (Japanese medaka) LC50 48 hours 33 mg/L 19 その他 Tonogai Y. et al. Actual survey on TLm (median tolerance limit) values of environmental pollutants, especially on amines, nitriles, aromatic nitrogen compounds and artificial dyes. J. Toxicol Sci., 7 (3) 2021/04/21
魚類 Brachydanio rerio (Zebrafish) NOEC 96 hours 0.039 mg/L × × 19 その他 Groth G. et al. Toxicity Studies in Fertilized Zebrafish Eggs Treated with N-Methylamine, N,N-Dimethylamine, 2-Aminoethanol, Isopropylamine, Aniline, N-Methylaniline, N,N-Dimethylaniline, Quinone, Chloroacetaldehyde, or Cyclohexanol. Bull Environ. Contam. Toxicol. 50 (6) 2021/04/21
魚類 Oryzias latipes (Japanese medaka) LC50 48 hours 78 mg/L × × 19 その他 Tonogai Y. et al. Studies of the syncopic effect of aniline derivatives on fish. The problem concerning the determination of median lethal concentration in fish. Eisei Kagaku (J. Hygienic Chemistry), 29 (5) 2021/04/21
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours 65.6 mg/L 19 その他 Broderius S. and Kahl M. Acute toxicity of organic chemical mixtures to the fathead minnow Aquatic Toxicology, 6 (4) 2021/04/21
魚類 Carassius auratus (Goldfish) LC50 48 hours 69 mg/L 19 その他 Tonogai Y. et al. Studies of the syncopic effect of aniline derivatives on fish. The problem concerning the determination of median lethal concentration in fish. Eisei Kagaku, 29 (5) 2021/04/21
魚類 Oryzias latipes (Japanese medaka) Mortality/Mortality LC50 48 hours 33000 μg/L × 16 ECOTOX Tonogai,Y., S. Ogawa, Y. Ito, and M. Iwaida Actual Survey on TLM (Median Tolerance Limit) Values of Environmental Pollutants, Especially on Amines, Nitriles, Aromatic Nitrogen Compounds J. Toxicol. Sci.7(3) 2020/11/12
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 48 hours 98 mg/L × × 14 BUA Report Tonogai, Y., Ogawa, S., Ito, Y. and Iwaida, M. Studies of the syncopic effect of aniline derivatives on fish. The problem concerning the determination of median lethal concentration in fish. Eisei Kagaku, 29 2021/03/16
魚類 Poecilia reticulata (Guppy) Mortality/Mortality LC50 96 hours 53700 μg/L ○ 16 ECOTOX Ramos,E.U., C. Vermeer, W.H.J. Vaes, and J.L.M. Hermens Acute Toxicity of Polar Narcotics to Three Aquatic Species (Daphnia magna, Poecilia reticulata and Lymnaea stagnalis) and Its Relation to Hydrophobicity Chemosphere37(4) 2020/11/12
魚類 Oryzias latipes (Japanese medaka) LC50 48 hours 76 mg/L 19 その他 Yoshioka, Y. et al. Testing and evaluation of chemical toxicity on Tubifex. Eisei Kagaku, 32 (4) 2021/04/21
魚類 Danio rerio (Zebrafish) Mortality LC50 96 hours 51.1 mg/L × × 14 BUA Report van Wijk, R.J. and Kraaij, R. Use of model parameter estimations from standard fish toxicity tests to indicate toxic mechanisms Bull Environ Contam Toxicol, 53 2021/03/16
魚類 Pimephales promelas loss of equilibrium EC50 96 hours 75.2 mg/L 12 ECHA Information on Registered Substances ACToR Database GCID : 42825 ACToR (Aggregated Computational Toxicology Resource) 2021/03/02
魚類 Poecilia reticulata (Guppy) Mortality/Mortality LC50 24 hours 55400 μg/L ○ 16 ECOTOX Ramos,E.U., C. Vermeer, W.H.J. Vaes, and J.L.M. Hermens Acute Toxicity of Polar Narcotics to Three Aquatic Species (Daphnia magna, Poecilia reticulata and Lymnaea stagnalis) and Its Relation to Hydrophobicity Chemosphere37(4) 2020/11/12
魚類 Pimephales promelas mortality LC50 96 hours 78.2 mg/L 12 ECHA Information on Registered Substances GCID : 42825 ACToR ;Brooke, L.T., D.J. Call, D.T. Geiger et.al.;Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales Promelas).Superior, WI 2021/03/02
魚類 Poecilia reticulata (Guppy) Mortality/Mortality LC50 72 hours 53700 μg/L ○ 16 ECOTOX Ramos,E.U., C. Vermeer, W.H.J. Vaes, and J.L.M. Hermens Acute Toxicity of Polar Narcotics to Three Aquatic Species (Daphnia magna, Poecilia reticulata and Lymnaea stagnalis) and Its Relation to Hydrophobicity Chemosphere37(4) 2020/11/12
魚類 Cyprinus carpio (Carp) mortality LC (Lethal concentration) 5.79 days 34～101 mg/L 12 ECHA Information on Registered Substances QSAR for CAS No. 121-69-7 OECD QSAR toolbox version 2.2, 2011;Loeb,H.A., and W.H. Kelly,1963,Acute Oral Toxicity of 1,496 Chemicals Force-Fed to Carp,U.S.Fish.Wildl.Serv., Sp.Sci.Rep.-Fish.No.471, Washington, D.C. 2021/03/02
魚類 Cyprinus carpio (Carp) mortality LC0 5.79 days 34～101 mg/L 12 ECHA Information on Registered Substances Loeb,H.A., and W.H. Kelly, Acute Oral Toxicity of 1,496 Chemicals Force-Fed to Carp U.S. Fish and Wildlife Service, Sp.Sci.Rep.-Fish.No.471, Washington, D.C. 2021/03/02