生態影響に係る有害性情報


CAS登録番号 CAS RN ® : 121-87-9
官報公示整理番号 METI No. : 3-407
物質名 test material : 2-クロロ-4-ニトロアニリン /Benzenamine, 2-chloro-4-nitro-
水溶解度 water solubility : 889.4mg/L (推計値 estimated)
LogKow : 2.14 (実測値 measured)
備考 remarks
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書) / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし 4:情報が少なく評価不能
日本環境省 化学物質の環境リスク評価(生態リスク初期評価) A:試験は信頼できる B:試験は条件付きで信頼できる C:試験の信頼性は低い D:信頼性の判定不可 E:信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり Supplemental:条件付きで信頼性あり Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり:○
なし:×
情報源 情報源による
信頼性評価**
著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value
exposure
duration
unit
toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material
original work type original work
reliability rank
author title referenced journal publication year Information
update date
藻類 Raphidocelis subcapitata Population/Population growth rate EC50 48 hours 15 Active ingredient × 16 ECOTOX Kusk,K.O., A.M. Christensen, and N. Nyholm Algal Growth Inhibition Test Results of 425 Organic Chemical Substances Chemosphere204 2022/09/15
藻類 Raphidocelis subcapitata Population/Population growth rate EC10 48 hours 3.4 Active ingredient × 16 ECOTOX Kusk,K.O., A.M. Christensen, and N. Nyholm Algal Growth Inhibition Test Results of 425 Organic Chemical Substances Chemosphere204 2022/09/15
甲殻類 Daphnia magna Intoxication/Immobile EC50 48 hours 1.8 Active ingredient × 16 ECOTOX Canton,J.H., W. Slooff, H.J. Kool, J. Struys, T.J.M. Pouw, R.C.C. Wegman, and G.J. Piet Toxicity, Biodegradability, and Accumulation of a Number of Cl/N-Containing Compounds for Classification and Establishing Water Quality Criteria Regul. Toxicol. Pharmacol.5 2022/09/15
甲殻類 Daphnia magna Intoxication/Immobile EC50 48 hours 1.7 Active ingredient 16 ECOTOX Pedersen,F., E. Bjornestad, T. Vulpius, and H.B. Rasmussen Immobilisation Test of Aniline Compounds with the Crustacean Daphnia magna Proj.No.303587, Report to the Danish EPA, Copenhagen, Denmark 2022/09/15
甲殻類 Daphnia magna EC50 48 hours 10~18 mg/L 14 BUA Report Hoechest AG o-Chloro-p-nitroaniline HOE CG 0421 0D ZD79 001 prolonged toxicity study over 21 days in Daphnia magna (water flea) Report No. 92.0855 1992 2023/01/31
甲殻類 Daphnia magna immobilization EC50 48 hours 1.8 mg/L 18 その他 PRTR生態毒性 2022/07/06
甲殻類 Daphnia magna Mortality/Mortality LC50 48 hours 5.6 Active ingredient × 16 ECOTOX Canton,J.H., W. Slooff, H.J. Kool, J. Struys, T.J.M. Pouw, R.C.C. Wegman, and G.J. Piet Toxicity, Biodegradability, and Accumulation of a Number of Cl/N-Containing Compounds for Classification and Establishing Water Quality Criteria Regul. Toxicol. Pharmacol.5 2022/09/15
甲殻類 Daphnia magna Intoxication/Immobile EC50 24 hours >4.2 Active ingredient 16 ECOTOX Pedersen,F., E. Bjornestad, T. Vulpius, and H.B. Rasmussen Immobilisation Test of Aniline Compounds with the Crustacean Daphnia magna Proj.No.303587, Report to the Danish EPA, Copenhagen, Denmark 2022/09/15
甲殻類 Daphnia magna immobility LOEC 21 days 10 mg/L nominal 14 BUA Report Hoechest AG o-Chloro-p-nitroaniline HOE CG 0421 0D ZD79 001 prolonged toxicity study over 21 days in Daphnia magna (water flea) Report No. 92.0855 1992 2023/02/21
甲殻類 Daphnia magna reproduction NOEC 21 days >=3.2 mg/L nominal 14 BUA Report Hoechest AG o-Chloro-p-nitroaniline HOE CG 0421 0D ZD79 001 prolonged toxicity study over 21 days in Daphnia magna (water flea) Report No. 92.0855 1992 2023/02/21
甲殻類 Daphnia magna immobility NOEC 21 days 3.2 mg/L nominal 14 BUA Report Hoechest AG o-Chloro-p-nitroaniline HOE CG 0421 0D ZD79 001 prolonged toxicity study over 21 days in Daphnia magna (water flea) Report No. 92.0855 1992 2023/02/21
魚類 Pimephales promelas LC50 96 days 20.4 mg/L test mat. 12 ECHA Information on Registered Substances Broderius SJ et al Toxicity to fish Broderius SJ et al; Environ Toxicol Chem 14 (9): 1591-1605 (1995) Available from, as of October 1, 2007 (HSDB Database) 2022/08/10
魚類 Pimephales promelas Mortality/Mortality LC50 96 hours 18900 Active ingredient 16 ECOTOX Brooke,L.T., D.J. Call, D.L. Geiger, and C.E. Northcott Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales promelas), Vol. 1 Center for Lake Superior Environmental Studies, University of Wisconsin-Superior, Superior, WI 2022/09/15
魚類 Pimephales promelas Mortality/Mortality LC50 96 hours 20400 Active ingredient 16 ECOTOX Broderius,S.J., M.D. Kahl, and M.D. Hoglund Use of Joint Toxic Response to Define the Primary Mode of Toxic Action for Diverse Industrial Organic Chemicals Environ. Toxicol. Chem.14(9) 2022/09/15
魚類 Pimephales promelas Mortality/Mortality LC50 96 hours 21500 Active ingredient 16 ECOTOX Brooke,L.T., D.J. Call, D.L. Geiger, and C.E. Northcott Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales promelas), Vol. 1 Center for Lake Superior Environmental Studies, University of Wisconsin-Superior, Superior, WI 2022/09/15