生態影響に係る有害性情報


CAS登録番号 CAS RN ® : 123-91-1
官報公示整理番号 METI No. : 5-839
物質名 test material : 1,4-ジオキサン /1,4-Dioxane
水溶解度 water solubility : 1000000mg/L (推計値 estimated)
LogKow
備考 remarks
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書) / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし 4:情報が少なく評価不能
日本環境省 化学物質の環境リスク評価(生態リスク初期評価) A:試験は信頼できる B:試験は条件付きで信頼できる C:試験の信頼性は低い D:信頼性の判定不可 E:信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり Supplemental:条件付きで信頼性あり Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり:○
なし:×
情報源 情報源による
信頼性評価**
著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value
exposure
duration
unit
toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material
original work type original work
reliability rank
author title referenced journal publication year Information
update date
甲殻類 Daphnia magna Physiology LC50 1 days 4700000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bringmann,G., and R. Kuhn Results of the Damaging Effect of Water
Pollutants on Daphnia magna (Befunde der
Schadwirkung Wassergefahrdender
Stoffe Gegen Daphnia magna)
TR-79-1204, Literature Research Company,
Annandale, VA:26 p.
1977 2016/03/25
甲殻類 Daphnia magna Behavior EC100 1 days 10000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bringmann,G., and R. Kuehn Results of Toxic Action of Water Pollutants on
Daphnia magna Straus Tested by an Improved
Standardized Procedure
Z. Wasser-Abwasser-Forsch.15(1): 1-6 1982 2016/03/25
甲殻類 Daphnia magna Behavior EC0 1 days 6210000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bringmann,G., and R. Kuehn Results of Toxic Action of Water Pollutants on
Daphnia magna Straus Tested by an Improved
Standardized Procedure
Z. Wasser-Abwasser-Forsch.15(1): 1-6 1982 2016/03/25
甲殻類 Daphnia magna Physiology LC0 1 days 2070000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bringmann,G., and R. Kuhn Results of the Damaging Effect of Water
Pollutants on Daphnia magna (Befunde der
Schadwirkung Wassergefahrdender
Stoffe Gegen Daphnia magna)
TR-79-1204, Literature Research Company,
Annandale, VA:26 p.
1977 2016/03/25
甲殻類 Daphnia magna Physiology LC100 1 days 10000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bringmann,G., and R. Kuhn Results of the Damaging Effect of Water
Pollutants on Daphnia magna (Befunde der
Schadwirkung Wassergefahrdender
Stoffe Gegen Daphnia magna)
TR-79-1204, Literature Research Company,
Annandale, VA:26 p.
1977 2016/03/25
甲殻類 Daphnia magna Behavior EC50 1 days 8450000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bringmann,G., and R. Kuehn Results of Toxic Action of Water Pollutants on
Daphnia magna Straus Tested by an Improved
Standardized Procedure
Z. Wasser-Abwasser-Forsch.15(1): 1-6 1982 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects 28 days 565000~6933000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Johnson,R., J. Tietge, G. Stokes, and D.
Lothenbach
The Medaka Carcinogenesis Model In: Tech.Rep.9306, Compendium of the FY1988 &
FY1989 Res.Rev.for the Res.Methods Branch, U.S.
Army Biomedical Res.& Dev.Lab., Ft.Detrick,
Frederick, MD:147-172
1993 2016/03/25
魚類 Cyprinus carpio (Carp) Mortality 3 days 99~167 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Loeb,H.A., and W.H. Kelly Acute Oral Toxicity of 1,496 Chemicals Force-Fed
to Carp
U.S.Fish.Wildl.Serv., Sp.Sci.Rep.-Fish.No.471,
Washington, D.C.:124 p.
1963 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 10800000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Geiger,D.L., L.T. Brooke, and D.J. Call Acute Toxicities of Organic Chemicals to Fathead
Minnows (Pimephales promelas), Volume V
Center for Lake Superior Environmental Studies,
University of Wisconsin, Superior, WI:332 p.
1990 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth 28 days 3536000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Johnson,R., J. Tietge, G. Stokes, and D.
Lothenbach
The Medaka Carcinogenesis Model In: Tech.Rep.9306, Compendium of the FY1988 &
FY1989 Res.Rev.for the Res.Methods Branch, U.S.
Army Biomedical Res.& Dev.Lab., Ft.Detrick,
Frederick, MD:147-172
1993 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality 28 days 6933000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Johnson,R., J. Tietge, G. Stokes, and D.
Lothenbach
The Medaka Carcinogenesis Model In: Tech.Rep.9306, Compendium of the FY1988 &
FY1989 Res.Rev.for the Res.Methods Branch, U.S.
Army Biomedical Res.& Dev.Lab., Ft.Detrick,
Frederick, MD:147-172
1993 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality 28 days 3536000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Johnson,R., J. Tietge, G. Stokes, and D.
Lothenbach
The Medaka Carcinogenesis Model In: Tech.Rep.9306, Compendium of the FY1988 &
FY1989 Res.Rev.for the Res.Methods Branch, U.S.
Army Biomedical Res.& Dev.Lab., Ft.Detrick,
Frederick, MD:147-172
1993 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality 28 days 547000~6960000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Johnson,R., J. Tietge, G. Stokes, and D.
Lothenbach
The Medaka Carcinogenesis Model In: Tech.Rep.9306, Compendium of the FY1988 &
FY1989 Res.Rev.for the Res.Methods Branch, U.S.
Army Biomedical Res.& Dev.Lab., Ft.Detrick,
Frederick, MD:147-172
1993 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality EC50 2 days 4269000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Brooke,L. Report of the Flow-Through and Static Acute Test
Comparisons with Fathead Minnows and Acute Tests
with an Amphipod and a Cladoceran
Memo to L.Larson, Center for Lake Superior
Environmental Studies dated August 31:24 p.
1987 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 4 days >10000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Dawson,G.W., A.L. Jennings, D. Drozdowski, and E.
Rider
The Acute Toxicity of 47 Industrial Chemicals to
Fresh and Saltwater Fishes
J. Hazard. Mater.1(4): 303-318 1977 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 9872000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Brooke,L. Report of the Flow-Through and Static Acute Test
Comparisons with Fathead Minnows and Acute Tests
with an Amphipod and a Cladoceran
Memo to L.Larson, Center for Lake Superior
Environmental Studies dated August 31:24 p.
1987 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth 28 days 1870000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Johnson,R., J. Tietge, G. Stokes, and D.
Lothenbach
The Medaka Carcinogenesis Model In: Tech.Rep.9306, Compendium of the FY1988 &
FY1989 Res.Rev.for the Res.Methods Branch, U.S.
Army Biomedical Res.& Dev.Lab., Ft.Detrick,
Frederick, MD:147-172
1993 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 12326000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Brooke,L. Report of the Flow-Through and Static Acute Test
Comparisons with Fathead Minnows and Acute Tests
with an Amphipod and a Cladoceran
Memo to L.Larson, Center for Lake Superior
Environmental Studies dated August 31:24 p.
1987 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 9850000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Geiger,D.L., L.T. Brooke, and D.J. Call Acute Toxicities of Organic Chemicals to Fathead
Minnows (Pimephales promelas), Volume V
Center for Lake Superior Environmental Studies,
University of Wisconsin, Superior, WI:332 p.
1990 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality 28 days 547000~6960000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Johnson,R., J. Tietge, and G. Stokes Validation of the Medaka Assay for Chemical
Carcinogens
In: Technical Report 9306, Compendium of the
FY1988 & FY1989 Research Reviews for the
Research Methods Branch, U.S. Army
Biomedical Research & Development
Lab., Ft. Detrick,
Frederick, MD:45-60
1993 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 48 hours 10600 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) - Biodegradation and Bioaccumulation Data of
Existing Chemicals Based on the CSCL Japan
1992 2016/02/08
魚類 Leuciscus idus (Orfe) Mortality LC50 96 hours 8410 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Furusjö, E., Andersson, M., Rahmberg, M., Svenson,
A.
Estimating environmentally important properties
of chemicals from the chemical structure
2003 2016/02/08
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 96 hours 10400 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Russom, C.L., Bradbury, S.P., Broderius, S.J.,
Drummond, R.A. and Hammermeister, D.E.
PREDICTING MODES OF TOXIC ACTION FROM CHEMICAL
STRUCTURE: ACUTE TOXICITY IN THE FATHEAD MINNOW
(PIMEPHALES PROMELAS)
1997 2016/02/08