生態影響に係る有害性情報


CAS登録番号 CAS RN ® ： 127-19-5
官報公示整理番号　METI No. ： 2-723
物質名 test material ： Ｎ，Ｎ－ジメチルアセトアミド　／N,N-Dimethylacetamide
水溶解度 water solubility ： 1000000mg/L (推計値 estimated)
LogKow ：
備考 remarks ：
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書） / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし　4:情報が少なく評価不能
日本環境省　化学物質の環境リスク評価（生態リスク初期評価） A：試験は信頼できる　B：試験は条件付きで信頼できる　C：試験の信頼性は低い　D：信頼性の判定不可　E：信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり　Supplemental:条件付きで信頼性あり　Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり：○
なし：×		 情報源 情報源による
信頼性評価**		 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value		 exposure
duration
unit		 toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material		 original work type original work
reliability rank		 author title referenced journal publication year Information
update date
藻類 Desmodesmus subspicatus biomass EC50 72 hours >500 mg/L × 12 ECHA Information on Registered Substances 2 study report 1989 2016/02/26
藻類 Desmodesmus subspicatus growth rate EC50 72 hours >500 mg/L × 12 ECHA Information on Registered Substances 2 study report 1989 2016/02/26
藻類 Desmodesmus subspicatus yield EC50 72 hours >500 mg/L × 12 ECHA Information on Registered Substances 2 study report 1989 2016/02/26
藻類 Scenedesmus subspicatus biomass EC50 72 hours >500 mg/L × 4 OECD SIDS (HPVC) BASF (DIN 52900) Safety Data Sheet-DIMETHYLACETAMIDE-June 1990. (Du Pont-Haskell Laboratory-Internal DMAC Review, Oct. 1988). 1988 2016/02/17
藻類 Desmodesmus subspicatus 生長阻害 EC50 72 hours >500 mg/L 11 Japan チャレンジプログラム - - AIDA (13/11/92)-ALSTOFF INFORMATION Date Bank from BASF AG Ecological Laboratory-Unpublished Data. 1988 2016/03/04
藻類 Desmodesmus subspicatus 生長阻害 EC50 72 hours >500 mg/L 11 Japan チャレンジプログラム - - BASF AG, Labor Oekologie; unveroeffentlichte Untersuchung, (1021/88) 1988 2016/03/04
藻類 Desmodesmus subspicatus yield NOEC 72 hours >=500 mg/L × 12 ECHA Information on Registered Substances 2 study report 1989 2016/02/26
藻類 Desmodesmus subspicatus yield LOEC 72 hours >500 mg/L × 12 ECHA Information on Registered Substances 2 study report 1989 2016/02/26
藻類 Desmodesmus subspicatus biomass NOEC 72 hours >=62.5 mg/L × 12 ECHA Information on Registered Substances 2 study report 1989 2016/02/26
藻類 Desmodesmus subspicatus biomass LOEC 72 hours 125 mg/L × 12 ECHA Information on Registered Substances 2 study report 1989 2016/02/26
藻類 Desmodesmus subspicatus growth rate LOEC 72 hours >500 mg/L × 12 ECHA Information on Registered Substances 2 study report 1989 2016/02/26
藻類 Desmodesmus subspicatus biomass EC10 72 hours 90.77 mg/L × 12 ECHA Information on Registered Substances 2 study report 1989 2016/02/26
藻類 Desmodesmus subspicatus growth rate NOEC 72 hours >=500 mg/L × 12 ECHA Information on Registered Substances 2 study report 1989 2016/02/26
甲殻類 Daphnia magna mobility EC0 48 hours 500 mg/L × 12 ECHA Information on Registered Substances 2 study report 1988 2016/02/26
甲殻類 Daphnia magna mobility EC50 48 hours >500 mg/L × 12 ECHA Information on Registered Substances 2 study report 1988 2016/02/26
甲殻類 Daphnia magna mobility EC100 48 hours >500 mg/L × 12 ECHA Information on Registered Substances 2 study report 1988 2016/02/26
甲殻類 Daphnia magna 遊泳阻害 EC50 48 hours >1000 mg/L 11 Japan チャレンジプログラム Adema,D.M.M., van den Bos Bakker,G.H. - TNO report, No. R 86/326 a, Order No. 16603/13518 Division of technology for society, Netherlands organization for applied scientific research 1987 2016/03/04
甲殻類 Daphnia magna 遊泳阻害 EC0 48 hours 500 mg/L 11 Japan チャレンジプログラム - - BASF AG, Labor Oekologie; unveroeffentlichte Untersuchung, (1021/88) 1988 2016/03/04
甲殻類 Daphnia magna 遊泳阻害 EC50 24 hours >500 mg/L 11 Japan チャレンジプログラム - - BASF AG, Labor Oekologie; unveroeffentlichte Untersuchung, (1021/88) 1988 2016/03/04
甲殻類 Daphnia magna 遊泳阻害 EC100 48 hours >500 mg/L 11 Japan チャレンジプログラム - - BASF AG, Labor Oekologie; unveroeffentlichte Untersuchung, (1021/88) 1988 2016/03/04
甲殻類 Daphnia magna EC100 48 hours >1000 mg/L 4 OECD SIDS (HPVC) Adema D.M.M. and G.H. van den Bos Bakker Aquatic toxicity of compounds that may be carried by ships (Marpol 1973, Annex II). A progress report for 1986. Report n. R 86/326a. TNO Netherlands 1987 2016/02/17
甲殻類 Daphnia magna 遊泳阻害 EC50 48 hours >500 mg/L 11 Japan チャレンジプログラム - - BASF AG, Labor Oekologie; unveroeffentlichte Untersuchung, (1021/88) 1988 2016/03/04
甲殻類 Daphnia magna 遊泳阻害 EC100 48 hours >500 mg/L 11 Japan チャレンジプログラム - - AIDA (13/11/92)-ALSTOFF INFORMATION Date Bank from BASF AG, Ecological Laboratory-Unpublished Data (1021/88) 1988 2016/03/04
甲殻類 Daphnia magna 遊泳阻害 EC0 48 hours 500 mg/L 11 Japan チャレンジプログラム - - AIDA (13/11/92)-ALSTOFF INFORMATION Date Bank from BASF AG, Ecological Laboratory-Unpublished Data (1021/88) 1988 2016/03/04
甲殻類 Daphnia magna 遊泳阻害 EC50 24 hours >500 mg/L 11 Japan チャレンジプログラム - - AIDA (13/11/92)-ALSTOFF INFORMATION Date Bank from BASF AG, Ecological Laboratory-Unpublished Data (1021/88) 1988 2016/03/04
甲殻類 Daphnia magna 遊泳阻害 EC0 24 hours 500 mg/L 11 Japan チャレンジプログラム - - BASF AG, Labor Oekologie; unveroeffentlichte Untersuchung, (1021/88) 1988 2016/03/04
甲殻類 Daphnia magna 遊泳阻害 EC100 24 hours >500 mg/L 11 Japan チャレンジプログラム - - AIDA (13/11/92)-ALSTOFF INFORMATION Date Bank from BASF AG, Ecological Laboratory-Unpublished Data (1021/88) 1988 2016/03/04
甲殻類 Daphnia magna 遊泳阻害 EC0 48 hours >=1000 mg/L 11 Japan チャレンジプログラム Adema,D.M.M., van den Bos Bakker,G.H. - TNO report, No. R 86/326 a, Order No. 16603/13518 Division of technology for society, Netherlands organization for applied scientific research 1987 2016/03/04
甲殻類 Daphnia magna 遊泳阻害 EC50 96 hours >1000 mg/L 11 Japan チャレンジプログラム Adema,D.M.M., van den Bos Bakker,G.H. - TNO report, No. R 86/326 a, Order No. 16603/13518 Division of technology for society, Netherlands organization for applied scientific research 1987 2016/03/04
甲殻類 Daphnia magna 遊泳阻害 EC100 24 hours >500 mg/L 11 Japan チャレンジプログラム - - BASF AG, Labor Oekologie; unveroeffentlichte Untersuchung, (1021/88) 1988 2016/03/04
甲殻類 Daphnia magna 遊泳阻害 EC100 48 hours >1000 mg/L 11 Japan チャレンジプログラム Adema,D.M.M., van den Bos Bakker,G.H. - TNO report, No. R 86/326 a, Order No. 16603/13518 Division of technology for society, Netherlands organization for applied scientific research 1987 2016/03/04
甲殻類 Daphnia magna 遊泳阻害 EC0 24 hours 500 mg/L 11 Japan チャレンジプログラム - - AIDA (13/11/92)-ALSTOFF INFORMATION Date Bank from BASF AG, Ecological Laboratory-Unpublished Data (1021/88) 1988 2016/03/04
甲殻類 Daphnia magna 遊泳阻害 EC0 96 hours >=1000 mg/L 11 Japan チャレンジプログラム Adema,D.M.M., van den Bos Bakker,G.H. - TNO report, No. R 86/326 a, Order No. 16603/13518 Division of technology for society, Netherlands organization for applied scientific research 1987 2016/03/04
甲殻類 Daphnia magna 遊泳阻害 EC50 48 hours >500 mg/L 11 Japan チャレンジプログラム - - AIDA (13/11/92)-ALSTOFF INFORMATION Date Bank from BASF AG, Ecological Laboratory-Unpublished Data (1021/88) 1988 2016/03/04
甲殻類 Daphnia magna 遊泳阻害 EC100 96 hours >1000 mg/L 11 Japan チャレンジプログラム Adema,D.M.M., van den Bos Bakker,G.H. - TNO report, No. R 86/326 a, Order No. 16603/13518 Division of technology for society, Netherlands organization for applied scientific research 1987 2016/03/04
甲殻類 Daphnia magna EC50 48 hours >1000 mg/L 4 OECD SIDS (HPVC) Adema D.M.M. and G.H. van den Bos Bakker Aquatic toxicity of compounds that may be carried by ships (Marpol 1973, Annex II). A progress report for 1986. Report n. R 86/326a. TNO Netherlands 1987 2016/02/17
甲殻類 Daphnia magna EC100 48 hours >500 mg/L × 4 OECD SIDS (HPVC) BASF Safety Data Sheet-DIMETHYLACETAMIDE-June 1990.(Du Pont-Haskell Laboratory-Internal DMAC Review, Oct. 1988). 1988 2016/02/22
甲殻類 Daphnia magna EC0 48 hours >=1000 mg/L 4 OECD SIDS (HPVC) Adema D.M.M. and G.H. van den Bos Bakker Aquatic toxicity of compounds that may be carried by ships (Marpol 1973, Annex II). A progress report for 1986. Report n. R 86/326a. TNO Netherlands 1987 2016/02/17
甲殻類 Daphnia magna EC50 48 hours >500 mg/L × 4 OECD SIDS (HPVC) BASF Safety Data Sheet-DIMETHYLACETAMIDE-June 1990.(Du Pont-Haskell Laboratory-Internal DMAC Review, Oct. 1988). 1988 2016/02/22
甲殻類 Daphnia magna EC0 24 hours 500 mg/L × 4 OECD SIDS (HPVC) BASF Safety Data Sheet-DIMETHYLACETAMIDE-June 1990.(Du Pont-Haskell Laboratory-Internal DMAC Review, Oct. 1988). 1988 2016/02/22
甲殻類 Daphnia magna EC50 24 hours >500 mg/L × 4 OECD SIDS (HPVC) BASF Safety Data Sheet-DIMETHYLACETAMIDE-June 1990.(Du Pont-Haskell Laboratory-Internal DMAC Review, Oct. 1988). 1988 2016/02/22
甲殻類 Daphnia magna EC0 48 hours 500 mg/L × 4 OECD SIDS (HPVC) BASF Safety Data Sheet-DIMETHYLACETAMIDE-June 1990.(Du Pont-Haskell Laboratory-Internal DMAC Review, Oct. 1988). 1988 2016/02/22
甲殻類 Daphnia magna EC100 24 hours >500 mg/L × 4 OECD SIDS (HPVC) BASF Safety Data Sheet-DIMETHYLACETAMIDE-June 1990.(Du Pont-Haskell Laboratory-Internal DMAC Review, Oct. 1988). 1988 2016/02/22
甲殻類 Daphnia magna NOEC 48 hours >=1000 mg/L 4 OECD SIDS (HPVC) Adema D.M.M. and G.H. van den Bos Bakker Aquatic toxicity of compounds that may be carried by ships (Marpol 1973, Annex II). A progress report for 1986. Report n. R 86/326a. TNO Netherlands 1987 2016/02/17
魚類 Danio rerio (Zebrafish) Mortality 12 hours 5～10 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Lahnsteiner,F. The Effect of Internal and External Cryoprotectants on Zebrafish (Danio rerio) Embryos Theriogenology69(3): 384-396 2008 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) No Group Code 1 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Applegate,V.C., J.H. Howell, A.E.,Jr. Hall, and M.A. Smith Toxicity of 4,346 Chemicals to Larval Lampreys and Fishes Spec.Sci.Rep.Fish.No.207, Fish Wildl.Serv., U.S.D.I., Washington, DC:157 p. 1957 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality EC0 2 days 6300000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Lahnsteiner,F. The Sensitivity and Reproducibility of the Zebrafish (Danio rerio) Embryo Test for the Screening of Waste Water Quality and for Testing the Toxicity of Chemicals Alt. Lab. Anim. (ATLA)36(3): 299-311 2008 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality EC50 2 days 16800000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Lahnsteiner,F. The Sensitivity and Reproducibility of the Zebrafish (Danio rerio) Embryo Test for the Screening of Waste Water Quality and for Testing the Toxicity of Chemicals Alt. Lab. Anim. (ATLA)36(3): 299-311 2008 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 2 days 1000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tonogai,Y., S. Ogawa, Y. Ito, and M. Iwaida Actual Survey on TLM (Median Tolerance Limit) Values of Environmental Pollutants, Especially on Amines, Nitriles, Aromatic Nitrogen Compounds J. Toxicol. Sci.7(3): 193-203 1982 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 1 days 1000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tonogai,Y., S. Ogawa, Y. Ito, and M. Iwaida Actual Survey on TLM (Median Tolerance Limit) Values of Environmental Pollutants, Especially on Amines, Nitriles, Aromatic Nitrogen Compounds J. Toxicol. Sci.7(3): 193-203 1982 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LD0 2 days 0.125 % v/v 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Lahnsteiner,F. The Effect of Internal and External Cryoprotectants on Zebrafish (Danio rerio) Embryos Theriogenology69(3): 384-396 2008 2016/03/25
魚類 Lepomis macrochirus (Bluegill) No Group Code 1 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Applegate,V.C., J.H. Howell, A.E.,Jr. Hall, and M.A. Smith Toxicity of 4,346 Chemicals to Larval Lampreys and Fishes Spec.Sci.Rep.Fish.No.207, Fish Wildl.Serv., U.S.D.I., Washington, DC:157 p. 1957 2016/03/25
魚類 Leuciscus idus (Orfe) mortality LC50 96 hours >500 mg/L × 12 ECHA Information on Registered Substances 2 study report 1979 2016/02/26
魚類 Oncorhynchus mykiss (Rainbow trout) 死亡 LC50 24 hours >5 mg/L 11 Japan チャレンジプログラム Applegate, V.C. et al. Toxicity of 4346 chemicals to larval lampreys and fishes Special Sci. Report Fishes, Special Sci. Report - Fisheries No. 207( 1957 2016/03/04
魚類 Lepomis macrochirus (Bluegill) 死亡 LC50 24 hours 5 mg/L × 11 Japan チャレンジプログラム Applegate, V.C. et al. Toxicity of 4346 chemicals to larval lampreys and fishes Special Sci. Report Fishes, Special Sci. Report - Fisheries No. 207( 1957 2016/03/04
魚類 Leuciscus idus (Orfe) 死亡 LC50 96 hours >500 mg/L × 11 Japan チャレンジプログラム BASF AG - Toxikologie, unveroeffentlichte Untersuchungen ZST Nr. 78/277 1979 2016/03/04
魚類 Leuciscus idus (Orfe) LC50 96 hours >500 mg/L × 4 OECD SIDS (HPVC) BASF AG Unpublished report 1979 2016/02/17
魚類 Oryzias latipes (Japanese medaka) 死亡 LC50 24 hours 1000 mg/L 11 Japan チャレンジプログラム Tonogai Y. and Y. Ito AIDA (13/11/92)-ALSTOFF INFORMATION Date Bank Seitai Kagaku, 7 1984 2016/03/04
魚類 Leuciscus idus (Orfe) LC0 96 hours 500 mg/L × 4 OECD SIDS (HPVC) BASF AG Unpublished report 1979 2016/02/22
魚類 Leuciscus idus (Orfe) LC100 96 hours >500 mg/L × 4 OECD SIDS (HPVC) BASF AG Unpublished report 1979 2016/02/17
魚類 Oryzias latipes (Japanese medaka) LC50 48 hours 1000 mg/L 4 OECD SIDS (HPVC) Tonogai Y., Ogawa S., Ito Y. and M. Iwai J. Toxicol. Sci., 7 1982 2016/02/17
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours >=1500 mg/L 4 OECD SIDS (HPVC) Geiger D.L. et al. Acute toxicities of organic chemical to fathead minnows pimephales-promelas). Vol. V. Superior WI 1990 2016/02/19