生態影響に係る有害性情報


CAS登録番号 CAS RN ® ： 1310-73-2
官報公示整理番号　METI No. ： 1-410
物質名 test material ： 水酸化ナトリウム　／Sodium hydroxide
水溶解度 water solubility ： 1000000mg/L (推計値 estimated)
LogKow ： -3.88 (推計値 estimated)
備考 remarks ：
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書） / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし　4:情報が少なく評価不能
日本環境省　化学物質の環境リスク評価（生態リスク初期評価） A：試験は信頼できる　B：試験は条件付きで信頼できる　C：試験の信頼性は低い　D：信頼性の判定不可　E：信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり　Supplemental:条件付きで信頼性あり　Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり：○
なし：×		 情報源 情報源による
信頼性評価**		 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value		 exposure
duration
unit		 toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material		 original work type original work
reliability rank		 author title referenced journal publication year Information
update date
甲殻類 Ceriodaphnia dubia Physiology EC50 2 days 40380 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Warne,M.S.J., and A.D. Schifko Toxicity of Laundry Detergent Components to a Freshwater Cladoceran and Their Contribution to Detergent Toxicity Ecotoxicol. Environ. Saf.44(2): 196-206 1999 2016/03/25
甲殻類 Daphnia magna Physiology NOEC 2 days 156000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Anderson,B.G. The Toxicity Thresholds of Various Sodium Salts Determined by the Use of Daphnia magna Sewage Works J.18(1): 82-87 1946 2016/03/25
甲殻類 Daphnia sp. Mortality 2 days 100000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Horn,W.M., J.B. Anderson, and M. Katz The Effect of Kraft Pulp Mill Wastes on Some Aquatic Organisms Trans. Am. Fish. Soc.79:55-63 1949 2016/03/25
甲殻類 Daphnia magna Physiology NOEC 16 hours 240000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Anderson,B.G. The Toxicity Thresholds of Various Substances Found in Industrial Wastes as Determined by the Use of Daphnia magna Sewage Works J.16(6): 1156-1165 1944 2016/03/25
甲殻類 Ceriodaphnia dubia Physiology EC50 2 days 40380 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Warne,M.S.J., and A.D. Schifko Toxicity of Laundry Detergent Components to a Freshwater Cladoceran and Their Contribution to Detergent Toxicity Ecotoxicol. Environ. Saf.44(2): 196-206 1999 2016/03/25
甲殻類 Ceriodaphnia sp. immobility EC50 48 hours 40.4 mg/L × 12 ECHA Information on Registered Substances 2 Warne M.St.J. and A.D. schifko Toxicity of Laundry Detergent Components to a Freshwater Cladoceran and their Contribution to Detergent Toxicity Ecotoxicology and Environmental Safety 1999 2016/02/26
甲殻類 Daphnia magna 40～240 7 EU Risk Assessment Report (EUリスク評価書） 4 McKee JE and Wolf Water Quality Criteria (2th edition; reprint 1976). California State Water Resources Control Board, United States. 1963 2016/02/25
甲殻類 Ceriodaphnia dubia LC50 48 hours 40 mg/L 7 EU Risk Assessment Report (EUリスク評価書） 2 Warne MSJ et al. Toxicity of Laundry Detergent Components to a Freshwater Cladoceran and their Contribution to Detergent Toxicity. Ecotoxicol. Environ. Safety 44 1963 2016/02/25
甲殻類 Ceriodaphnia sp. immobility EC50 48 hours 40.4 mg/L × 4 OECD SIDS (HPVC) 2 Warne MSJ Ecotoxicology and Environmental Safety 1999 2016/02/25
魚類 Carassius auratus (Goldfish) Mortality 100000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Sanborn,N.H. The Lethal Effect of Certain Chemicals on Fresh Water Fish The Canning Trade16(27): 10,12-15,26 1945 2016/03/25
魚類 Carassius auratus (Goldfish) Mortality 7 days 50000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Sanborn,N.H. The Lethal Effect of Certain Chemicals on Fresh Water Fish The Canning Trade16(27): 10,12-15,26 1945 2016/03/25
魚類 Carassius auratus (Goldfish) Mortality LC50 1 days 160000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Jensen,R.A. A Simplified Bioassay Using Finfish for Estimating Potential Spill Damage In: Proc. Control of Hazardous Material Spills, Rockville, MD:104-108 1978 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality 7 days 50000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Sanborn,N.H. The Lethal Effect of Certain Chemicals on Fresh Water Fish The Canning Trade16(27): 10,12-15,26 1945 2016/03/25
魚類 Poecilia reticulata (Guppy) Mortality LC50 1 days 145000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Yarzhombek,A.A., A.E. Mikulin, and A.N. Zhdanova Toxicity of Substances in Relation to Form of Exposure J. Ichthyol.31(7): 99-106 1991 2016/03/25
魚類 Leuciscus idus (Orfe) LC100 48 hours 213 mg/L × 12 ECHA Information on Registered Substances 4 Juhnke I and Luedemann D Ergebnisse der Untersuchung von 200 Chemischen Verbindungen auf Akute Fischtoxizität mit dem Goldorfentest Z Wasser Abwasser Forsch 1978 2016/02/26
魚類 Cyprinus carpio (Carp) LC100 24 hours 180 mg/L × 12 ECHA Information on Registered Substances 4 Nishiuchi Y Suisan Zoshoku 1975 2016/02/26
魚類 Poecilia reticulata (Guppy) mortality LC50 24 hours 145 mg/L 12 ECHA Information on Registered Substances 3 Yarzhombek et al Toxicity of Substances in Relation to Form of Exposure UDC 597.08.591.1.6 1991 2016/02/26
魚類 Leuciscus idus (Orfe) LC50 48 hours 189 mg/L × 12 ECHA Information on Registered Substances 4 Juhnke I and Luedemann D Ergebnisse der Untersuchung von 200 Chemischen Verbindungen auf Akute Fischtoxizität mit dem Goldorfentest Z Wasser Abwasser Forsch 1978 2016/02/26
魚類 Leuciscus idus (Orfe) LC0 48 hours 157 mg/L × 12 ECHA Information on Registered Substances 4 Juhnke I and Luedemann D Ergebnisse der Untersuchung von 200 Chemischen Verbindungen auf Akute Fischtoxizität mit dem Goldorfentest Z Wasser Abwasser Forsch 1978 2016/02/26
魚類 Leuciscus idus (Orfe) LC50 48 hours 189 mg/L 7 EU Risk Assessment Report (EUリスク評価書） 4 Juhnke I and Lüdemann D Ergebnisse der Untersuchung von 200 chemischen Verbindungen auf akute Fischtoxizität mit den Goldorfentest. Z. f. Wasser- und Abwasser-Forschung, 11 1978 2016/02/25
魚類 Carassius auratus (Goldfish) 100 mg/L 7 EU Risk Assessment Report (EUリスク評価書） 3 Jensen R A Simplified Bioassay Using Finfish for Estimating Potential Spill damage. Proc. control of hazardous material spills, Rockvill, MD 1978 2016/02/25
魚類 Poecilia reticulata (Guppy) LC50 24 hours 145 mg/L 7 EU Risk Assessment Report (EUリスク評価書） 3 Yarzhombek et al. Toxicity of Substances in Relation to Form of Exposure. 1991 2016/02/25
魚類 Carassius auratus (Goldfish) LC50 24 hours 160 mg/L 7 EU Risk Assessment Report (EUリスク評価書） 3 Jensen R A Simplified Bioassay Using Finfish for Estimating Potential Spill damage. Proc. control of hazardous material spills, Rockvill, MD 1978 2016/02/25
魚類 Carassius auratus (Goldfish) mortality LC50 24 hours 160 mg/L × 4 OECD SIDS (HPVC) 3 Jensen RA Simplified bioassay using finfish for estimating potential spill damage Proc. control of hazardous material spills 1978 2016/02/25
魚類 Poecilia reticulata (Guppy) mortality LC50 24 hours 145 mg/L 4 OECD SIDS (HPVC) 3 Yarzhombek et al Voprosy Ikhtiologii 1991 2016/02/25
魚類 Leuciscus idus (Orfe) LC50 48 hours 189 mg/L × 4 OECD SIDS (HPVC) 4 Juhnke et al Z Wasser Abwasser Forsch 1978 2016/02/25
魚類 Leuciscus idus (Orfe) LC50 48 hours 213 mg/L × 4 OECD SIDS (HPVC) 4 Juhnke et al Z Wasser Abwasser Forsch 1978 2016/02/25
魚類 Leuciscus idus (Orfe) LC0 48 hours 157 mg/L × 4 OECD SIDS (HPVC) 4 Juhnke et al Z Wasser Abwasser Forsch 1978 2016/02/25
魚類 Cyprinus carpio (Carp) LC50 24 hours 180 mg/L × 4 OECD SIDS (HPVC) 4 Nishiuchi Y Suisan Zoshoku 1975 2016/02/25