生態影響に係る有害性情報


CAS登録番号 CAS RN ® : 134-62-3
官報公示整理番号 METI No. : 3-1321
物質名 test material : N,N-ジエチル-m-トルアミド /N,N-diethyl-3-methylbenzamide
水溶解度 water solubility : 666mg/L (推計値 estimated)
LogKow : 2.18 (実測値 measured)
備考 remarks
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書) / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし 4:情報が少なく評価不能
日本環境省 化学物質の環境リスク評価(生態リスク初期評価) A:試験は信頼できる B:試験は条件付きで信頼できる C:試験の信頼性は低い D:信頼性の判定不可 E:信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり Supplemental:条件付きで信頼性あり Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり:○
なし:×
情報源 情報源による
信頼性評価**
著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value
exposure
duration
unit
toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material
original work type original work
reliability rank
author title referenced journal publication year Information
update date
藻類 Pseudokirchneriella subcapitata EC50 72 hours 72 mg/L 1 日本環境省 生態リスク初期評価 環境省 (Ⅱ-1)生態影響試験(藻類、甲殻類、魚類)結果一覧(平成27年3月版) 2016/11/10
藻類 Pseudokirchneriella subcapitata EC50 72 hours >100 mg/L 1 日本環境省 生態リスク初期評価 環境省 (Ⅱ-1)生態影響試験(藻類、甲殻類、魚類)結果一覧(平成27年3月版) 2016/11/10
藻類 Pseudokirchneriella subcapitata NOEC 72 hours 32 mg/L 1 日本環境省 生態リスク初期評価 環境省 (Ⅱ-1)生態影響試験(藻類、甲殻類、魚類)結果一覧(平成27年3月版) 2016/11/10
藻類 Pseudokirchneriella subcapitata NOEC 72 hours 32 mg/L 1 日本環境省 生態リスク初期評価 環境省 (Ⅱ-1)生態影響試験(藻類、甲殻類、魚類)結果一覧(平成27年3月版) 2016/11/10
甲殻類 Daphnia magna Physiology NOEL 2 days 32000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly: Environmental Effects Database (EEDB)) Environmental Fate and Effects Division, U.S.EPA, Washington, D.C.: 1992 2016/03/25
甲殻類 Daphnia magna Physiology EC50 2 days 75000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly: Environmental Effects Database (EEDB)) Environmental Fate and Effects Division, U.S.EPA, Washington, D.C.: 1992 2016/03/25
甲殻類 Daphnia magna Cellular Effects 3 days 10000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Hannas,B.R., Y.H. Wang, S. Thomson, G. Kwon, H. Li, and G.A. LeBlanc Regulation and Dysregulation of Vitellogenin mRNA Accumulation in Daphnids (Daphnia magna) Aquat. Toxicol.101(2): 351-357 2011 2016/03/25
甲殻類 Daphnia magna EC50 48 hours 75 mg/L 3 USEPA Pesticide Ecotoxicity Database D. Balluff 1989 2016/02/02
甲殻類 Daphnia magna EC50 48 hours 74 mg/L 1 日本環境省 生態リスク初期評価 環境省 (Ⅱ-1)生態影響試験(藻類、甲殻類、魚類)結果一覧(平成27年3月版) 2016/11/10
甲殻類 Daphnia magna NOEL 48 hours 32 mg/L 3 USEPA Pesticide Ecotoxicity Database D. Balluff 1989 2016/02/02
甲殻類 Daphnia magna EC50 21 days 20 mg/L 1 日本環境省 生態リスク初期評価 環境省 (Ⅱ-1)生態影響試験(藻類、甲殻類、魚類)結果一覧(平成27年3月版) 2016/11/10
甲殻類 Daphnia magna NOEC 21 days 7.2 mg/L 1 日本環境省 生態リスク初期評価 環境省 (Ⅱ-1)生態影響試験(藻類、甲殻類、魚類)結果一覧(平成27年3月版) 2016/11/10
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 110000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Brooke,L.T., D.J. Call, D.L. Geiger, and C.E. Northcott Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales promelas), Vol. 1 Center for Lake Superior Environmental Studies, University of Wisconsin-Superior, Superior, WI:414 p. 1984 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality NOEL 4 days 56000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly: Environmental Effects Database (EEDB)) Environmental Fate and Effects Division, U.S.EPA, Washington, D.C.: 1992 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 4 days 75000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly: Environmental Effects Database (EEDB)) Environmental Fate and Effects Division, U.S.EPA, Washington, D.C.: 1992 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 4 days 71250 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly: Environmental Effects Database (EEDB)) Environmental Fate and Effects Division, U.S.EPA, Washington, D.C.: 1992 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects LOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Danio rerio (Zebrafish) No Group Code 5 days 80 μM 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Padilla,S., D. Corum, B. Padnos, D.L. Hunter, A. Beam, K.A. Houck, N. Sipes, N. Kleinstreuer, T. Knudsen, D.J. Dix, and Zebrafish Developmental Screening of the ToxCast Phase I Chemical Library Reprod. Toxicol.33(2): 174-187 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 2 days 0.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zenobio,J.E., B.C. Sanchez, L.C. Archuleta, and M.S. Sepulveda Effects of Triclocarban, N,N-Diethyl-meta-Toluamide, and a Mixture of Pharmaceuticals and Personal Care Products on Fathead Minnows (Pimephales promelas) Environ. Toxicol. Chem.33(4): 910-919 2014 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours 75 mg/L 3 USEPA Pesticide Ecotoxicity Database J. McCann 1972 2016/02/02
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours 71.25 mg/L 3 USEPA Pesticide Ecotoxicity Database J. McCann 1979 2016/02/02
魚類 Oryzias latipes (Japanese medaka) LC50 96 hours >100 mg/L 1 日本環境省 生態リスク初期評価 環境省 (Ⅱ-1)生態影響試験(藻類、甲殻類、魚類)結果一覧(平成27年3月版) 2016/11/10
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 96 hours 110 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Russom, C.L., Bradbury, S.P., Broderius, S.J., Drummond, R.A. and Hammermeister, D.E. PREDICTING MODES OF TOXIC ACTION FROM CHEMICAL STRUCTURE: ACUTE TOXICITY IN THE FATHEAD MINNOW (PIMEPHALES PROMELAS) 1997 2016/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 48 hours 100 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) - Biodegradation and Bioaccumulation Data of Existing Chemicals Based on the CSCL Japan 1992 2016/02/08
魚類 Oncorhynchus mykiss (Rainbow trout) NOEL 96 hours 56 mg/L 3 USEPA Pesticide Ecotoxicity Database J. McCann 1972 2016/02/02