生態影響に係る有害性情報


CAS登録番号 CAS RN ® : 137-26-8
官報公示整理番号 METI No. : 2-1820
物質名 test material : N,N,N’,N’-テトラメチル-2,3-ジチアジチオスクシンアミド /N,N,N',N'-Tetramethyl-2,3-dithiadithiosuccinamide
水溶解度 water solubility : 30mg/L (推計値 estimated)
LogKow : 1.73 (実測値 measured)
備考 remarks
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書) / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし 4:情報が少なく評価不能
日本環境省 化学物質の環境リスク評価(生態リスク初期評価) A:試験は信頼できる B:試験は条件付きで信頼できる C:試験の信頼性は低い D:信頼性の判定不可 E:信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり Supplemental:条件付きで信頼性あり Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり:○
なし:×
情報源 情報源による
信頼性評価**
著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value
exposure
duration
unit
toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material
original work type original work
reliability rank
author title referenced journal publication year Information
update date
藻類 Raphidocelis subcapitata growth rate EC5 72 hours 0.022 mg/L meas. (initial) act. ingr. 12 ECHA Information on Registered Substances 3 study report 1996 2023/08/04
藻類 Raphidocelis subcapitata Population/Abundance EC50 5 days 0.14 ppm Active ingredient 16 ECOTOX U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2023/07/14
藻類 Raphidocelis subcapitata Population/Abundance NOEL 5 days <0.057 ppm Active ingredient 16 ECOTOX U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2023/07/14
藻類 Raphidocelis subcapitata growth rate EC25 72 hours 0.15 mg/L meas. (initial) act. ingr. 12 ECHA Information on Registered Substances 3 study report 2001 2023/08/04
藻類 Scenedesmus acutus Mortality/Mortality NR-LETH 3 days 10000 μg/L Formulation × 16 ECOTOX Krishnakumari,M.K. Sensitivity of the Alga Scenedesmus acutus to
Some Pesticides
Life Sci.20: 1977 2023/07/14
藻類 Chlorella vulgaris Growth/Growth, general EC50 72 hours 5500 μg/L Formulation × 16 ECOTOX Jouany,J.M., R. Truhaut, P. Vasseur, D. Klein, J.
F. Ferard, and P. Deschamps
An Example of Interaction between Environmental
Pollutants: Modification of Thiram Toxicity to
Freshwater Organisms by Nitrites or Nitrates
in Relation to Nitrosamine Synthesis
Ecotoxicol. Environ. Saf.9(3): 1985 2023/07/14
藻類 Raphidocelis subcapitata Population/Abundance EC50 5 days 0.045 ppm Active ingredient 16 ECOTOX U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2023/07/14
藻類 Scenedesmus acutus Mortality/Mortality 3 days 10000 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Krishnakumari,M.K. Sensitivity of the Alga Scenedesmus acutus to
Some Pesticides
Life Sci.20 1977
藻類 Chlorella pyrenoidosa Growth/Growth, general EC50 4 hours 1000 μg/L Active ingredient × 16 ECOTOX Van Leeuwen,C.J., J.L. Maas-Diepeveen, G. Niebeek,
W.H.A. Vergouw, P.S. Griffioen, and M.W.
Luijken
Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. I. Short-Term Toxicity
Tests
Aquat. Toxicol.7(3): 1985 2023/07/14
藻類 Raphidocelis subcapitata growth rate EC20 72 hours 86.2 μg/L meas. (geom. mean) test mat. 12 ECHA Information on Registered Substances 1 study report 2015 2023/08/04
藻類 Chlorella pyrenoidosa Growth/Growth, general EC50 96 hours 1000 μg/L Active ingredient × 16 ECOTOX Van Leeuwen,C.J., J.L. Maas-Diepeveen, G. Niebeek,
W.H.A. Vergouw, P.S. Griffioen, and M.W.
Luijken
Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. I. Short-Term Toxicity
Tests
Aquat. Toxicol.7(3): 1985 2023/07/14
藻類 Pseudokirchneriella subcapitata growth rate NOEC 72 hours 0.03 mg/L Conc. based on: test mat. 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Growth inhibition test of Bis
(dimethylthiocarbamoyl) disulfide on fresh water
alga
2008 2018/12/06
藻類 Pseudokirchneriella subcapitata growth rate LOEC 72 hours 0.1 mg/L Conc. based on: test mat. 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Growth inhibition test of Bis
(dimethylthiocarbamoyl) disulfide on fresh water
alga
2008 2018/12/06
藻類 Pseudokirchneriella subcapitata biomass (area under growth curve method)
LOEC 72 hours 0.1 mg/L Conc. based on: test mat. 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Growth inhibition test of Bis
(dimethylthiocarbamoyl) disulfide on fresh water
alga
2008 2018/12/06
藻類 others Haematococcus pluvialis Population (Population changes, general)
EC10 >6 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Knie,J., A. Halke, I. Juhnke, and W. Schiller Results of Studies on Chemical Substances with
Four Biotests (Ergebnisse der Untersuch-Ungen
von Chemischen Stoffen mit vier Biotests)
Dtsch. Gewaesserkd. Mitt.27(3): 77-79 1983 2019/02/13
藻類 Pseudokirchneriella subcapitata growth rate EC50 72 hours 0.19 mg/L Conc. based on: test mat. 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Growth inhibition test of Bis
(dimethylthiocarbamoyl) disulfide on fresh water
alga
2008 2018/12/06
藻類 Pseudokirchneriella subcapitata Population (Abundance) NOEL 5 days <0.057 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
藻類 Chlorella vulgaris IC50 72 hours 5.5 mg/L 4 OECD SIDS (HPVC) 3 Jouany JM, Truhaut R, Vasseur P, Klein D, Ferard
JF and Deschamps P
An example of interaction between environmental
pollutants: Modification of thiram toxicity to
freshwater organisms by nitrites or nitrates
in relation to nitrosamine synthesis
Ecotoxicology and environmental safety 1985 2018/12/06
藻類 Pseudokirchneriella subcapitata biomass (area under growth curve method)
LOEC 72 hours 0.1 mg/L Conc. based on: test mat. 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Growth inhibition test of Bis
(dimethylthiocarbamoyl) disulfide on fresh water
alga
2008 2018/12/06
藻類 Pseudokirchneriella subcapitata biomass (area under growth curve method)
EC50 72 hours 0.06 mg/L Conc. based on: test mat. 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Growth inhibition test of Bis
(dimethylthiocarbamoyl) disulfide on fresh water
alga
2008 2018/12/06
藻類 Pseudokirchneriella subcapitata biomass (area under growth curve method)
LOEC 72 hours 0.03 mg/L Conc. based on: test mat. 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Growth inhibition test of Bis
(dimethylthiocarbamoyl) disulfide on fresh water
alga
2008 2018/12/06
藻類 Pseudokirchneriella subcapitata Population (Abundance) EC50 5 days 0.045 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
藻類 Chlorella vulgaris IC50 72 hours 5.5 mg/L 4 OECD SIDS (HPVC) 3 Jouany JM, Truhaut R, Vasseur P, Klein D, Ferard
JF and Deschamps P
An example of interaction between environmental
pollutants: Modification of thiram toxicity to
freshwater organisms by nitrites or nitrates
in relation to nitrosamine synthesis
Ecotoxicology and environmental safety 1985 2018/12/06
藻類 Pseudokirchneriella subcapitata growth rate NOEC 72 hours 0.03 mg/L Conc. based on: test mat. 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Growth inhibition test of Bis
(dimethylthiocarbamoyl) disulfide on fresh water
alga
2008 2018/12/06
藻類 Pseudokirchneriella subcapitata 生長阻害 ErC50 72 hours 16.7 μg/L 2 日本環境省 農薬登録保留基準(水産動植物) 2018/12/18
藻類 Chlorella vulgaris Growth (Growth, general) EC50 3 days 5.5 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Jouany,J.M., R. Truhaut, P. Vasseur, D. Klein, J.
F. Ferard, and P. Deschamps
An Example of Interaction between Environmental
Pollutants: Modification of Thiram Toxicity to
Freshwater Organisms by Nitrites or Nitrates
in Relation to Nitrosamine Synthesis
Ecotoxicol. Environ. Saf.9(3): 327-338 1985 2019/02/13
藻類 Pseudokirchneriella subcapitata biomass (area under growth curve method)
LOEC 72 hours 0.03 mg/L Conc. based on: test mat. 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Growth inhibition test of Bis
(dimethylthiocarbamoyl) disulfide on fresh water
alga
2008 2018/12/06
藻類 Pseudokirchneriella subcapitata growth rate EC50 72 hours 0.19 mg/L Conc. based on: test mat. 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Growth inhibition test of Bis
(dimethylthiocarbamoyl) disulfide on fresh water
alga
2008 2018/12/06
藻類 others Nannochloropsis oculata Population (Population growth rate) EC50 3 days 0.04 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kyriakopoulou,K., P. Anastasiadou, and K. Machera Comparative Toxicities of Fungicide and Herbicide
Formulations on Freshwater and Marine Species
Bull. Environ. Contam. Toxicol.82(3): 290-295 2009 2019/02/13
藻類 others Nannochloropsis oculata Population (Population growth rate) EC50 1 days 0.04 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kyriakopoulou,K., P. Anastasiadou, and K. Machera Comparative Toxicities of Fungicide and Herbicide
Formulations on Freshwater and Marine Species
Bull. Environ. Contam. Toxicol.82(3): 290-295 2009 2019/02/13
藻類 others Chlorella pyrenoidosa Growth (Growth, general) EC50 4 days 1 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., J.L. Maas-Diepeveen, G. Niebeek,
W.H.A. Vergouw, P.S. Griffioen, and M.W.
Luijken
Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. I. Short-Term Toxicity
Tests
Aquat. Toxicol.7(3): 145-164 1985 2019/02/13
藻類 others Scenedesmus acutus Mortality NR-LETH 3 days 10 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Krishnakumari,M.K. Sensitivity of the Alga Scenedesmus acutus to
Some Pesticides
Life Sci.20:1525-1532 1977 2025/05/02
藻類 others Nannochloropsis oculata Population (Population growth rate) EC50 2 days 0.04 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kyriakopoulou,K., P. Anastasiadou, and K. Machera Comparative Toxicities of Fungicide and Herbicide
Formulations on Freshwater and Marine Species
Bull. Environ. Contam. Toxicol.82(3): 290-295 2009 2019/02/13
藻類 Pseudokirchneriella subcapitata biomass (area under growth curve method)
EC50 72 hours 0.06 mg/L Conc. based on: test mat. 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Growth inhibition test of Bis
(dimethylthiocarbamoyl) disulfide on fresh water
alga
2008 2018/12/06
藻類 others Chlorella pyrenoidosa Growth (Growth, general) EC50 0.16 days 1 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., J.L. Maas-Diepeveen, G. Niebeek,
W.H.A. Vergouw, P.S. Griffioen, and M.W.
Luijken
Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. I. Short-Term Toxicity
Tests
Aquat. Toxicol.7(3): 145-164 1985 2019/02/13
藻類 Pseudokirchneriella subcapitata growth rate LOEC 72 hours 0.1 mg/L Conc. based on: test mat. 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Growth inhibition test of Bis
(dimethylthiocarbamoyl) disulfide on fresh water
alga
2008 2018/12/06
藻類 Pseudokirchneriella subcapitata 生長阻害 NOECr 72 hours 4.3 μg/L 2 日本環境省 農薬登録保留基準(水産動植物) 2018/12/18
藻類 Pseudokirchneriella subcapitata Population (Abundance) EC50 5 days 0.14 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
藻類 Chlorella vulgaris Growth EC50 3 days 5500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Jouany,J.M., R. Truhaut, P. Vasseur, D. Klein, J.
F. Ferard, and P. Deschamps
An Example of Interaction between Environmental
Pollutants: Modification of Thiram Toxicity to
Freshwater Organisms by Nitrites or Nitrates
in Relation to Nitrosamine Synthesis
Ecotoxicol. Environ. Saf.9(3): 327-338 1985 2016/03/25
藻類 Pseudokirchneriella subcapitata Population EC50 5 days 140 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2016/03/25
藻類 Pseudokirchneriella subcapitata Population EC50 5 days 45 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2016/03/25
藻類 Pseudokirchneriella subcapitata Population NOEL 5 days <57 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2016/03/25
藻類 Pseudokirchneriella subcapitata Population/Abundance EC50 5 days 0.14 ppm Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.
1992
藻類 Pseudokirchneriella subcapitata Population/Abundance EC50 5 days 0.045 ppm Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.
1992
藻類 Chlorella pyrenoidosa Growth/Growth, general EC50 4 hours 1000 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., J.L. Maas-Diepeveen, G. Niebeek,
W.H.A. Vergouw, P.S. Griffioen, and M.W.
Luijken
Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. I. Short-Term Toxicity
Tests
Aquat. Toxicol.7(3) 1985
藻類 Chlorella pyrenoidosa Growth/Growth, general EC50 96 hours 1000 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., J.L. Maas-Diepeveen, G. Niebeek,
W.H.A. Vergouw, P.S. Griffioen, and M.W.
Luijken
Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. I. Short-Term Toxicity
Tests
Aquat. Toxicol.7(3) 1985
藻類 Pseudokirchneriella subcapitata Growth EC50 3 days 141 µg/L 17 Aquatic OASIS (OECD QSAR Toolbox) EFSA doi:10.2903/j.efsa.2017.4700 http://dx.doi.org/10.2903/j.efsa.2017.4700 2017 2023/07/18
藻類 Pseudokirchneriella subcapitata growth rate EC50 24 hours 0.12 mg/L 12 ECHA Information on Registered Substances 1 study report 1993
藻類 Pseudokirchneriella subcapitata biomass EC50 120 hours 0.076 mg/L 12 ECHA Information on Registered Substances 1 study report 1993 2020/03/04
藻類 Pseudokirchneriella subcapitata biomass EC50 72 hours 0.065 mg/L 12 ECHA Information on Registered Substances 1 study report 1993
藻類 Chlorella vulgaris Growth/Growth, general EC50 72 hours 5500 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Jouany,J.M., R. Truhaut, P. Vasseur, D. Klein, J.
F. Ferard, and P. Deschamps
An Example of Interaction between Environmental
Pollutants: Modification of Thiram Toxicity to
Freshwater Organisms by Nitrites or Nitrates
in Relation to Nitrosamine Synthesis
Ecotoxicol. Environ. Saf.9(3) 1985
藻類 Pseudokirchneriella subcapitata Population/Abundance NOEL 5 days <0.057 ppm Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.
1992
藻類 Selenastrum capricornutum growth rate EC50 24 hours 0.12 mg/L 12 ECHA Information on Registered Substances 1 study report 1993 2016/03/18
藻類 Selenastrum capricornutum biomass EC50 72 hours 0.065 mg/L 12 ECHA Information on Registered Substances 1 study report 1993 2016/03/18
藻類 Selenastrum capricornutum EC50 5 days 45 μg/L 3 USEPA Pesticide Ecotoxicity Database B. Montague 1993 2016/02/02
藻類 Selenastrum capricornutum biomass EC50 120 hours 0.076 mg/L 12 ECHA Information on Registered Substances 1 study report 1993 2016/03/18
藻類 Selenastrum capricornutum EC50 5 days 140 μg/L 3 USEPA Pesticide Ecotoxicity Database J. Edwards 1998 2016/02/02
藻類 Chlorella sp. Chlorella pyrenoidosa breakdown products EC50 96 hours 1 mg/L 10 EHC (Environmental Health Criteria) VAN LEEUWEN, C.J. Ecotoxicological aspects of dithiocarbamates Utrecht, University of Utrecht (Thesis). 1986 2018/12/13
藻類 Raphidocelis subcapitata growth rate EC50 24 hours 0.12 mg/L meas. (geom. mean) act. ingr. 12 ECHA Information on Registered Substances 3 study report 1993 2023/08/04
藻類 Raphidocelis subcapitata growth rate EC50 72 hours 0.49 mg/L meas. (initial) act. ingr. 12 ECHA Information on Registered Substances 3 study report 1993 2023/08/04
藻類 Raphidocelis subcapitata biomass EC50 72 hours 0.065 mg/L meas. (geom. mean) act. ingr. 12 ECHA Information on Registered Substances 3 study report 1996 2023/08/04
藻類 Raphidocelis subcapitata yield EC50 72 hours 69.5 μg/L meas. (geom. mean) test mat. 12 ECHA Information on Registered Substances 1 study report 2015 2023/08/04
藻類 Raphidocelis subcapitata biomass EC50 72 hours 0.16 mg/L meas. (initial) act. ingr. 12 ECHA Information on Registered Substances 3 study report 2001 2023/08/04
藻類 Raphidocelis subcapitata biomass EC50 120 hours 0.076 mg/L meas. (geom. mean) act. ingr. 12 ECHA Information on Registered Substances 3 study report 1993 2023/08/04
藻類 Raphidocelis subcapitata growth rate EC50 72 hours >141 μg/L meas. (geom. mean) test mat. 12 ECHA Information on Registered Substances 1 study report 2015 2023/08/04
藻類 Pseudokirchneriella subcapitata EC50 5 days 140 ppb 3 USEPA Pesticide Ecotoxicity Database J. Edwards Huntingdon Research Center, England 1992 2019/02/27
藻類 Pseudokirchneriella subcapitata EC50 5 days 45 ppb 3 USEPA Pesticide Ecotoxicity Database B. Montague Huntingdon Research Center, England 1992 2019/02/27
藻類 Chlorella vulgaris IC50 72 hours 5.5 mg/L 4 OECD SIDS (HPVC) 3 Jouany JM, Truhaut R, Vasseur P, Klein D, Ferard
JF and Deschamps P
An example of interaction between environmental
pollutants: Modification of thiram toxicity to
freshwater organisms by nitrites or nitrates
in relation to nitrosamine synthesis
Ecotoxicology and environmental safety 2008 2016/02/22
藻類 Pseudokirchneriella subcapitata biomass EC50 72 hours 0.06 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Growth inhibition test of Bis
(dimethylthiocarbamoyl) disulfide on fresh water
alga
2008 2016/02/22
藻類 Chlorella vulgaris Growth IC50 3 days 5500 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
a Jouany, J.M., R. Truhaut, P. Vasseur, D. Klein, J.
F. Ferard, and P. Deschamps
An Example of Interaction between Environmental
Pollutants: Modification of Thiram Toxicity to
Freshwater Organisms by Nitrites or Nitrates
in.
Ecotoxicol.Environ.Saf. 1985 2016/03/07
藻類 Pseudokirchneriella subcapitata growth rate EC50 72 hours 0.19 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Growth inhibition test of Bis
(dimethylthiocarbamoyl) disulfide on fresh water
alga
2008 2016/02/22
藻類 Chlorella sp. Chlorella pyrenoidosa EC50 96 hours 1 mg/L 10 EHC (Environmental Health Criteria) VAN LEEUWEN, C.J. Ecotoxicological aspects of dithiocarbamates Utrecht, University of Utrecht (Thesis) 2016/03/06
藻類 Anabaena sp. EC50 14 days 60 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
b Cameron, H.J., and G.R. Julian The Effects of Four Commonly used Fungicides on 
the Growth of Cyanobacteria.
Plant Soil 1984 2016/03/07
藻類 Scenedesmus sp. Scenedesmus acutus Growth EC50 5 days 5000 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
b Krishnakumari, M.K. Sensitivity of the Alga Scenedesmus acutus to
Some Pesticides.
Life Sci. 1977 2016/03/07
藻類 Chlorella sp. Chlorella pyrenoidosa Growth EC50 4 days 1000 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
a Van Leeuwen, C.J., J.L. Maas-Diepeveen, G.
Niebeek, W.H.A. Vergouw, P.S. Griffioen, and M.W.
Luijken
Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. I. Short-Term Toxicity
Tests.
Aquat.Toxicol. 1985 2016/03/07
藻類 Anabaena sp. EC50 14 days 6 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
b Cameron, H.J., and G.R. Julian The Effects of Four Commonly used Fungicides on 
the Growth of Cyanobacteria.
Plant Soil 1984 2016/03/07
藻類 Chlorella sp. Chlorella pyrenoidosa Biomass EC50 4 days 320 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
a Van Leeuwen, C.J., J.L. Maas-Diepeveen, G.
Niebeek, W.H.A. Vergouw, P.S. Griffioen, and M.W.
Luijken
Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. I. Short-Term Toxicity
Tests.
Aquat.Toxicol. 1985 2016/03/07
藻類 Pseudokirchneriella subcapitata 生長阻害 ErC50 72 hours 16.7 μg/L 2 日本環境省 農薬登録保留基準(水産動植物) 環境省 水産動植物の被害防止に係る農薬登録保留基準の設定に関する資料 2016/02/17
藻類 Pseudokirchneriella subcapitata 生長阻害 NOECr 72 hours 4.3 μg/L 2 日本環境省 農薬登録保留基準(水産動植物) 環境省 水産動植物の被害防止に係る農薬登録保留基準の設定に関する資料 2016/02/17
藻類 Selenastrum capricornutum NOEL 5 days 57 μg/L 3 USEPA Pesticide Ecotoxicity Database B. Montague 1993 2016/02/02
藻類 Raphidocelis subcapitata growth rate EC10 72 hours 56.9 μg/L meas. (geom. mean) test mat. 12 ECHA Information on Registered Substances 1 study report 2015 2023/08/04
藻類 Raphidocelis subcapitata growth rate NOEC 72 hours 29 μg/L meas. (geom. mean) test mat. 12 ECHA Information on Registered Substances 1 study report 2015 2023/08/04
藻類 Raphidocelis subcapitata yield EC10 72 hours 28.9 μg/L meas. (geom. mean) test mat. 12 ECHA Information on Registered Substances 1 study report 2015 2023/08/04
藻類 Pseudokirchneriella subcapitata NOEL 5 days <57 ppb 3 USEPA Pesticide Ecotoxicity Database B. Montague Huntingdon Research Center, England 1992 2019/02/27
藻類 Pseudokirchneriella subcapitata biomass LOEC 72 hours 0.03 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Growth inhibition test of Bis
(dimethylthiocarbamoyl) disulfide on fresh water
alga
2008 2016/02/22
藻類 Pseudokirchneriella subcapitata growth rate NOEC 72 hours 0.03 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Growth inhibition test of Bis
(dimethylthiocarbamoyl) disulfide on fresh water
alga
2008 2016/02/22
藻類 Pseudokirchneriella subcapitata growth rate LOEC 72 hours 0.1 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Growth inhibition test of Bis
(dimethylthiocarbamoyl) disulfide on fresh water
alga
2008 2016/02/22
藻類 Pseudokirchneriella subcapitata biomass LOEC 72 hours 0.1 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Growth inhibition test of Bis
(dimethylthiocarbamoyl) disulfide on fresh water
alga
2008 2016/02/22
甲殻類 Daphnia magna Mortality/Mortality NR-LETH 24 hours 1000 μg/L Formulation × 16 ECOTOX Jouany,J.M., R. Truhaut, P. Vasseur, D. Klein, J.
F. Ferard, and P. Deschamps
An Example of Interaction between Environmental
Pollutants: Modification of Thiram Toxicity to
Freshwater Organisms by Nitrites or Nitrates
in Relation to Nitrosamine Synthesis
Ecotoxicol. Environ. Saf.9(3): 1985 2023/07/14
甲殻類 Daphnia magna Behavior/Phototactic response NOEC 48 hours 37.5 μg/L Formulation × 16 ECOTOX Martins,J., M.L. Soares, M.L. Saker, L.
OlivaTeles, and V.M. Vasconcelos
Phototactic Behavior in Daphnia magna Straus as
an Indicator of Toxicants in the Aquatic
Environment
Ecotoxicol. Environ. Saf.67(3): 2007 2023/07/14
甲殻類 Americamysis bahia Mortality/Mortality LC50 96 hours 3.36 ppb Active ingredient 16 ECOTOX U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2023/07/14
甲殻類 Daphnia magna Mortality/Mortality LC50 48 hours 0.01 mg/L Formulation × 16 ECOTOX Kyriakopoulou,K., P. Anastasiadou, and K. Machera Comparative Toxicities of Fungicide and Herbicide
Formulations on Freshwater and Marine Species
Bull. Environ. Contam. Toxicol.82(3): 2009 2023/07/14
甲殻類 Crassostrea gigas Intoxication/Immobile EC50 48 hours 4.7 ppb Active ingredient 16 ECOTOX U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2023/07/14
甲殻類 Daphnia magna Behavior/Phototactic response NOEC 3.5 hours 150 μg/L Formulation × 16 ECOTOX Martins,J., M.L. Soares, M.L. Saker, L.
OlivaTeles, and V.M. Vasconcelos
Phototactic Behavior in Daphnia magna Straus as
an Indicator of Toxicants in the Aquatic
Environment
Ecotoxicol. Environ. Saf.67(3): 2007 2023/07/14
甲殻類 Daphnia magna Behavior/Distance moved, change in
direct movement
EC50 0.006 μg/L Formulation × 16 ECOTOX Knie,J., A. Halke, I. Juhnke, and W. Schiller Results of Studies on Chemical Substances with
Four Biotests (Ergebnisse der Untersuch-Ungen
von Chemischen Stoffen mit vier Biotests)
Dtsch. Gewaesserkd. Mitt.27(3): 1983 2023/07/14
甲殻類 Daphnia magna mobility EC50 48 hours >0.1 mg/L nominal test mat. × × 12 ECHA Information on Registered Substances 3 study report 1999 2023/12/21
甲殻類 Daphnia magna mobility EC50 24 hours 26 μg/L nominal act. ingr. 12 ECHA Information on Registered Substances 2 study report 1994 2023/12/21
甲殻類 Daphnia magna Mortality/Mortality LC50 48 hours 210 μg/L Active ingredient × 16 ECOTOX Van Leeuwen,C.J., J.L. Maas-Diepeveen, G. Niebeek,
W.H.A. Vergouw, P.S. Griffioen, and M.W.
Luijken
Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. I. Short-Term Toxicity
Tests
Aquat. Toxicol.7(3): 1985 2023/07/14
甲殻類 Crassostrea gigas Intoxication/Immobile NOEL 48 hours <1.3 ppb Active ingredient 16 ECOTOX U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2023/07/14
甲殻類 Daphnia magna Behavior/Phototactic response LOEC 3.5 hours 300 μg/L Formulation × 16 ECOTOX Martins,J., M.L. Soares, M.L. Saker, L.
OlivaTeles, and V.M. Vasconcelos
Phototactic Behavior in Daphnia magna Straus as
an Indicator of Toxicants in the Aquatic
Environment
Ecotoxicol. Environ. Saf.67(3): 2007 2023/07/14
甲殻類 Daphnia magna Mortality/Mortality NR-ZERO 210 minutes 9 μg/L Formulation × 16 ECOTOX Martins,J.C., M.L. Saker, L.F. Oliva Teles, and V.
M. Vasconcelos
Oxygen Consumption by Daphnia magna Straus as a
Marker of Chemical Stress in the Aquatic
Environment
Environ. Toxicol. Chem.26(9): 2007 2023/07/14
甲殻類 Daphnia magna Mortality/Mortality LC50 24 hours 0.03 mg/L Formulation × 16 ECOTOX Kyriakopoulou,K., P. Anastasiadou, and K. Machera Comparative Toxicities of Fungicide and Herbicide
Formulations on Freshwater and Marine Species
Bull. Environ. Contam. Toxicol.82(3): 2009 2023/07/14
甲殻類 Daphnia magna mobility EC50 48 hours 11 μg/L nominal act. ingr. 12 ECHA Information on Registered Substances 2 study report 1994 2023/12/21
甲殻類 Daphnia magna Physiology/Oxygen consumption LOEL 210 minutes 9 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Martins,J.C., M.L. Saker, L.F. Oliva Teles, and V.
M. Vasconcelos
Oxygen Consumption by Daphnia magna Straus as a
Marker of Chemical Stress in the Aquatic
Environment
Environ. Toxicol. Chem.26(9) 2007
甲殻類 Daphnia magna Mortality/Mortality NR-ZERO 210 minutes 9 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Martins,J.C., M.L. Saker, L.F. Oliva Teles, and V.
M. Vasconcelos
Oxygen Consumption by Daphnia magna Straus as a
Marker of Chemical Stress in the Aquatic
Environment
Environ. Toxicol. Chem.26(9) 2007 2025/05/02
甲殻類 Daphnia magna Behavior/Distance moved, change in
direct movement
EC50 0.006 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Knie,J., A. Halke, I. Juhnke, and W. Schiller Results of Studies on Chemical Substances with
Four Biotests (Ergebnisse der Untersuch-Ungen
von Chemischen Stoffen mit vier Biotests)
Dtsch. Gewaesserkd. Mitt.27(3) 1983
甲殻類 Daphnia magna Physiology/Oxygen consumption NOEL 15 minutes 9 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Martins,J.C., M.L. Saker, L.F. Oliva Teles, and V.
M. Vasconcelos
Oxygen Consumption by Daphnia magna Straus as a
Marker of Chemical Stress in the Aquatic
Environment
Environ. Toxicol. Chem.26(9) 2007
甲殻類 Daphnia magna mobility NOEC 48 hours 0.14 mg/L meas. (initial) act. ingr. 12 ECHA Information on Registered Substances 2 study report 2008 2023/12/21
甲殻類 Daphnia magna Behavior/Phototactic response LOEC 48 hours 75 μg/L Formulation × 16 ECOTOX Martins,J., M.L. Soares, M.L. Saker, L.
OlivaTeles, and V.M. Vasconcelos
Phototactic Behavior in Daphnia magna Straus as
an Indicator of Toxicants in the Aquatic
Environment
Ecotoxicol. Environ. Saf.67(3): 2007 2023/07/14
甲殻類 Daphnia magna Mortality/Mortality LC50 21 days 8 μg/L Active ingredient × 16 ECOTOX Van Leeuwen,C.J., F. Moberts, and G. Niebeek Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. II. Effects on Survival,
Reproduction and Growth of Daphnia magna
Aquat. Toxicol.7: 1988 2023/07/14
甲殻類 Daphnia magna mobility EC100 48 hours 1.3 mg/L meas. (initial) act. ingr. 12 ECHA Information on Registered Substances 2 study report 2008 2023/12/21
甲殻類 Daphnia magna immobilisation NOEC 21 days 40 μg/L meas. (arithm. mean) act. ingr. 12 ECHA Information on Registered Substances 1 study report 2008 2023/12/21
甲殻類 Americamysis bahia Mortality/Mortality NOEL 96 hours 2.3 ppb Active ingredient 16 ECOTOX U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2023/07/14
甲殻類 Daphnia magna reproduction NOEC 21 days 40 μg/L meas. (arithm. mean) act. ingr. 12 ECHA Information on Registered Substances 1 study report 2008 2023/12/21
甲殻類 Daphnia magna mortality and mobility LC50 14 days 86 μg/L nominal act. ingr. × 12 ECHA Information on Registered Substances 4 study report 2008 2023/12/21
甲殻類 Daphnia magna immobilisation EC50 21 days 57 μg/L meas. (arithm. mean) act. ingr. 12 ECHA Information on Registered Substances 1 study report 2008 2023/12/21
甲殻類 Daphnia magna growth and sub-lethal effects NOEC 21 days 20 μg/L meas. (arithm. mean) act. ingr. 12 ECHA Information on Registered Substances 1 study report 2008 2023/12/21
甲殻類 Daphnia magna mobility EC50 48 hours 0.18 mg/L nominal act. ingr. × × 12 ECHA Information on Registered Substances 3 study report 1999 2023/12/21
甲殻類 Daphnia magna mortality and mobility LC50 48 hours >0.2 mg/L nominal act. ingr. × 12 ECHA Information on Registered Substances 4 study report 2008 2023/12/21
甲殻類 Daphnia magna Behavior/Phototactic response LOEC 24 hours 9.38 μg/L Formulation × 16 ECOTOX Martins,J., M.L. Soares, M.L. Saker, L.
OlivaTeles, and V.M. Vasconcelos
Phototactic Behavior in Daphnia magna Straus as
an Indicator of Toxicants in the Aquatic
Environment
Ecotoxicol. Environ. Saf.67(3): 2007 2023/07/14
甲殻類 Daphnia magna reproduction EC50 21 days 70 μg/L meas. (arithm. mean) act. ingr. 12 ECHA Information on Registered Substances 1 study report 2008 2023/12/21
甲殻類 Daphnia magna Mortality/Mortality LC50 26 hours 1300 μg/L Formulation × 16 ECOTOX Frear,D.E.H., and J.E. Boyd Use of Daphnia magna for the Microbioassay of
Pesticides. I. Development of Standardized
Techniques for Rearing Daphnia and
Preparation of Dosage-Mortality Curves
for Pesticides
J. Econ. Entomol.60(5): 1967 2023/07/14
甲殻類 Daphnia magna mobility EC50 48 hours 0.38 mg/L meas. (initial) act. ingr. 12 ECHA Information on Registered Substances 2 study report 2008 2023/12/21
甲殻類 others Asellus aquaticus Mortality LC50 4 days 61 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., D. Marchal-Segault, and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, on Several Animals Species of Freshwater
(Toxicite Aigue d'un Fongicide
Dithiocarbamate, le Thirame, vis-a-vis de
Plusieurs Especes Animales
d'eau Douce)
Environ. Pollut. A.31(3): 177-189 1983 2019/02/13
甲殻類 others Gammarus pulex Mortality LC50 1 days 3.26 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bluzat,R., O. Jonot, and J. Seuge Acute Toxicity of a Fungicide, Thirame
(Dithiocarbamate) in the Freshwater Amphipodal
Crustacean Gammarus pulex
Environ. Pollut. A.29(3): 225-233 1982 2019/02/13
甲殻類 Daphnia magna Mortality LC50 1.08 days 1.3 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Frear,D.E.H., and J.E. Boyd Use of Daphnia magna for the Microbioassay of
Pesticides. I. Development of Standardized
Techniques for Rearing Daphnia and
Preparation of Dosage-Mortality
Curves for Pesticides
J. Econ. Entomol.60(5): 1228-1236 1967 2019/02/13
甲殻類 others Gammarus pulex Mortality LC50 4 days 0.13 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bluzat,R., O. Jonot, and J. Seuge Acute Toxicity of a Fungicide, Thirame
(Dithiocarbamate) in the Freshwater Amphipodal
Crustacean Gammarus pulex
Environ. Pollut. A.29(3): 225-233 1982 2019/02/13
甲殻類 others Gammarus pulex Mortality LC50 4 days 0.06 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bluzat,R., O. Jonot, and J. Seuge Acute Toxicity of a Fungicide, Thirame
(Dithiocarbamate) in the Freshwater Amphipodal
Crustacean Gammarus pulex
Environ. Pollut. A.29(3): 225-233 1982 2019/02/13
甲殻類 others Gammarus pulex Mortality LC50 3 days 0.4 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bluzat,R., O. Jonot, and J. Seuge Acute Toxicity of a Fungicide, Thirame
(Dithiocarbamate) in the Freshwater Amphipodal
Crustacean Gammarus pulex
Environ. Pollut. A.29(3): 225-233 1982 2019/02/13
甲殻類 others Gammarus pulex Mortality LC50 4 days 0.195 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bluzat,R., O. Jonot, and J. Seuge Acute Toxicity of a Fungicide, Thirame
(Dithiocarbamate) in the Freshwater Amphipodal
Crustacean Gammarus pulex
Environ. Pollut. A.29(3): 225-233 1982 2019/02/13
甲殻類 others Gammarus pulex Mortality LC50 4 days 0.225 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bluzat,R., O. Jonot, and J. Seuge Acute Toxicity of a Fungicide, Thirame
(Dithiocarbamate) in the Freshwater Amphipodal
Crustacean Gammarus pulex
Environ. Pollut. A.29(3): 225-233 1982 2019/02/13
甲殻類 others Gammarus pulex Mortality LC50 3 days 0.13 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bluzat,R., O. Jonot, and J. Seuge Acute Toxicity of a Fungicide, Thirame
(Dithiocarbamate) in the Freshwater Amphipodal
Crustacean Gammarus pulex
Environ. Pollut. A.29(3): 225-233 1982 2019/02/13
甲殻類 others Asellus aquaticus Mortality LC50 3 days 161 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., D. Marchal-Segault, and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, on Several Animals Species of Freshwater
(Toxicite Aigue d'un Fongicide
Dithiocarbamate, le Thirame, vis-a-vis de
Plusieurs Especes Animales
d'eau Douce)
Environ. Pollut. A.31(3): 177-189 1983 2019/02/13
甲殻類 others Artemia franciscana Mortality LC50 2 days 0.02 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kyriakopoulou,K., P. Anastasiadou, and K. Machera Comparative Toxicities of Fungicide and Herbicide
Formulations on Freshwater and Marine Species
Bull. Environ. Contam. Toxicol.82(3): 290-295 2009 2019/02/13
甲殻類 Daphnia magna Mortality LC50 2 days 0.01 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kyriakopoulou,K., P. Anastasiadou, and K. Machera Comparative Toxicities of Fungicide and Herbicide
Formulations on Freshwater and Marine Species
Bull. Environ. Contam. Toxicol.82(3): 290-295 2009 2019/02/13
甲殻類 Daphnia magna Intoxication EC50 48 hours 0.186621 mol/L 17 Aquatic OASIS (OECD QSAR Toolbox) Furusjö, E., Andersson, M., Rahmberg, M., Svenson,
A.
Estimating environmentally important properties
of chemicals from the chemical structure
Estimating environmentally important properties
of chemicals from the chemical structure - IVL
Rapport B1517
2003 2019/02/22
甲殻類 Daphnia magna Physiology (Oxygen consumption) NOEL 0.01 days 0.009 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Martins,J.C., M.L. Saker, L.F. Oliva Teles, and V.
M. Vasconcelos
Oxygen Consumption by Daphnia magna Straus as a
Marker of Chemical Stress in the Aquatic
Environment
Environ. Toxicol. Chem.26(9): 1987-1991 2007 2019/02/13
甲殻類 others Gammarus pulex Mortality LC50 2 days 1.21 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bluzat,R., O. Jonot, and J. Seuge Acute Toxicity of a Fungicide, Thirame
(Dithiocarbamate) in the Freshwater Amphipodal
Crustacean Gammarus pulex
Environ. Pollut. A.29(3): 225-233 1982 2019/02/13
甲殻類 others Gammarus pulex Mortality LC50 1 days 13.99 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bluzat,R., O. Jonot, and J. Seuge Acute Toxicity of a Fungicide, Thirame
(Dithiocarbamate) in the Freshwater Amphipodal
Crustacean Gammarus pulex
Environ. Pollut. A.29(3): 225-233 1982 2019/02/13
甲殻類 Daphnia magna Physiology (Oxygen consumption) LOEL 0.14 days 0.009 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Martins,J.C., M.L. Saker, L.F. Oliva Teles, and V.
M. Vasconcelos
Oxygen Consumption by Daphnia magna Straus as a
Marker of Chemical Stress in the Aquatic
Environment
Environ. Toxicol. Chem.26(9): 1987-1991 2007 2019/02/13
甲殻類 Unio tumidus Mortality NR-ZERO 3 days 0.1 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Doyotte,A., C. Cossu, M.C. Jacquin, M. Babut, and
P. Vasseur
Antioxidant Enzymes, Glutathione and Lipid
Peroxidation as Relevant Biomarkers of
Experimental or Field Exposure in the
Gills and the Digestive Gland
of the Freshwater Bivalve
Unio tumidus
Aquat. Toxicol.39:93-110 1997 2025/05/07
甲殻類 Daphnia magna Behavior (Distance moved, change in
direct movement)
EC50 0.000006 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Knie,J., A. Halke, I. Juhnke, and W. Schiller Results of Studies on Chemical Substances with
Four Biotests (Ergebnisse der Untersuch-Ungen
von Chemischen Stoffen mit vier Biotests)
Dtsch. Gewaesserkd. Mitt.27(3): 77-79 1983 2019/02/13
甲殻類 others Americamysis bahia Mortality NOEL 4 days 0.0023 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
甲殻類 Daphnia magna Mortality LC50 1 days 0.03 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kyriakopoulou,K., P. Anastasiadou, and K. Machera Comparative Toxicities of Fungicide and Herbicide
Formulations on Freshwater and Marine Species
Bull. Environ. Contam. Toxicol.82(3): 290-295 2009 2019/02/13
甲殻類 Daphnia magna Behavior (Phototactic response) LOEC 0.14 days 0.3 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Martins,J., M.L. Soares, M.L. Saker, L.
OlivaTeles, and V.M. Vasconcelos
Phototactic Behavior in Daphnia magna Straus as
an Indicator of Toxicants in the Aquatic
Environment
Ecotoxicol. Environ. Saf.67(3): 417-422 2007 2019/02/13
甲殻類 others Gammarus pulex Mortality LC50 2 days 0.36 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bluzat,R., O. Jonot, and J. Seuge Acute Toxicity of a Fungicide, Thirame
(Dithiocarbamate) in the Freshwater Amphipodal
Crustacean Gammarus pulex
Environ. Pollut. A.29(3): 225-233 1982 2019/02/13
甲殻類 Daphnia magna Behavior (Phototactic response) NOEC 2 days 0.0375 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Martins,J., M.L. Soares, M.L. Saker, L.
OlivaTeles, and V.M. Vasconcelos
Phototactic Behavior in Daphnia magna Straus as
an Indicator of Toxicants in the Aquatic
Environment
Ecotoxicol. Environ. Saf.67(3): 417-422 2007 2019/02/13
甲殻類 others Americamysis bahia Mortality LC50 4 days 0.00336 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
甲殻類 others Asellus aquaticus Mortality LC50 1 days 1882 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., D. Marchal-Segault, and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, on Several Animals Species of Freshwater
(Toxicite Aigue d'un Fongicide
Dithiocarbamate, le Thirame, vis-a-vis de
Plusieurs Especes Animales
d'eau Douce)
Environ. Pollut. A.31(3): 177-189 1983 2019/02/13
甲殻類 Daphnia magna Behavior (Phototactic response) LOEC 2 days 0.075 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Martins,J., M.L. Soares, M.L. Saker, L.
OlivaTeles, and V.M. Vasconcelos
Phototactic Behavior in Daphnia magna Straus as
an Indicator of Toxicants in the Aquatic
Environment
Ecotoxicol. Environ. Saf.67(3): 417-422 2007 2019/02/13
甲殻類 others Asellus aquaticus Mortality LC50 2 days 688 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., D. Marchal-Segault, and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, on Several Animals Species of Freshwater
(Toxicite Aigue d'un Fongicide
Dithiocarbamate, le Thirame, vis-a-vis de
Plusieurs Especes Animales
d'eau Douce)
Environ. Pollut. A.31(3): 177-189 1983 2019/02/13
甲殻類 Daphnia magna Behavior (Phototactic response) LOEC 1 days 0.00938 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Martins,J., M.L. Soares, M.L. Saker, L.
OlivaTeles, and V.M. Vasconcelos
Phototactic Behavior in Daphnia magna Straus as
an Indicator of Toxicants in the Aquatic
Environment
Ecotoxicol. Environ. Saf.67(3): 417-422 2007 2019/02/13
甲殻類 others Gammarus pulex Mortality LC50 3 days 0.41 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bluzat,R., O. Jonot, and J. Seuge Acute Toxicity of a Fungicide, Thirame
(Dithiocarbamate) in the Freshwater Amphipodal
Crustacean Gammarus pulex
Environ. Pollut. A.29(3): 225-233 1982 2019/02/13
甲殻類 Daphnia magna Mortality NR-ZERO 0.14 days 0.009 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Martins,J.C., M.L. Saker, L.F. Oliva Teles, and V.
M. Vasconcelos
Oxygen Consumption by Daphnia magna Straus as a
Marker of Chemical Stress in the Aquatic
Environment
Environ. Toxicol. Chem.26(9): 1987-1991 2007 2025/05/02
甲殻類 Daphnia magna Mortality NR-LETH 1 days 1 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Jouany,J.M., R. Truhaut, P. Vasseur, D. Klein, J.
F. Ferard, and P. Deschamps
An Example of Interaction between Environmental
Pollutants: Modification of Thiram Toxicity to
Freshwater Organisms by Nitrites or Nitrates
in Relation to Nitrosamine Synthesis
Ecotoxicol. Environ. Saf.9(3): 327-338 1985 2025/05/02
甲殻類 Daphnia magna Feeding behavior (Food consumption) EC50 0.04 days 0.279 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Fochtman,P., A. Raszka, and E. Nierzedska The Use of Conventional Bioassays, Microbiotests,
and Some "Rapid" Methods in the Selection of an
Optimal Test Battery for the Assessment of
Pesticides Toxicity
Environ. Toxicol.15(5): 376-384 2000 2019/02/13
甲殻類 Daphnia magna Mortality LC50 2 days 0.21 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., J.L. Maas-Diepeveen, G. Niebeek,
W.H.A. Vergouw, P.S. Griffioen, and M.W.
Luijken
Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. I. Short-Term Toxicity
Tests
Aquat. Toxicol.7(3): 145-164 1985 2019/02/13
甲殻類 others Gammarus pulex Mortality LC50 2 days 0.48 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bluzat,R., O. Jonot, and J. Seuge Acute Toxicity of a Fungicide, Thirame
(Dithiocarbamate) in the Freshwater Amphipodal
Crustacean Gammarus pulex
Environ. Pollut. A.29(3): 225-233 1982 2019/02/13
甲殻類 others Procambarus clarkii Mortality LC50 4 days 4.3 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Cheah,M.L., J.W.,Jr. Avault, and J.B. Graves Acute Toxicity of Selected Rice Pesticides to
Crayfish Procambarus clarkii
Prog. Fish-Cult.42(3): 169-172 1980 2019/02/13
甲殻類 others Artemia franciscana Mortality LC50 1 days 0.13 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kyriakopoulou,K., P. Anastasiadou, and K. Machera Comparative Toxicities of Fungicide and Herbicide
Formulations on Freshwater and Marine Species
Bull. Environ. Contam. Toxicol.82(3): 290-295 2009 2019/02/13
甲殻類 others Gammarus pulex Mortality LC50 2 days 0.87 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bluzat,R., O. Jonot, and J. Seuge Acute Toxicity of a Fungicide, Thirame
(Dithiocarbamate) in the Freshwater Amphipodal
Crustacean Gammarus pulex
Environ. Pollut. A.29(3): 225-233 1982 2019/02/13
甲殻類 others Gammarus pulex Mortality LC50 3 days 0.2 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bluzat,R., O. Jonot, and J. Seuge Acute Toxicity of a Fungicide, Thirame
(Dithiocarbamate) in the Freshwater Amphipodal
Crustacean Gammarus pulex
Environ. Pollut. A.29(3): 225-233 1982 2019/02/13
甲殻類 Daphnia magna Behavior (Phototactic response) NOEC 0.14 days 0.15 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Martins,J., M.L. Soares, M.L. Saker, L.
OlivaTeles, and V.M. Vasconcelos
Phototactic Behavior in Daphnia magna Straus as
an Indicator of Toxicants in the Aquatic
Environment
Ecotoxicol. Environ. Saf.67(3): 417-422 2007 2019/02/13
甲殻類 others Gammarus pulex Mortality LC50 1 days 1.37 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bluzat,R., O. Jonot, and J. Seuge Acute Toxicity of a Fungicide, Thirame
(Dithiocarbamate) in the Freshwater Amphipodal
Crustacean Gammarus pulex
Environ. Pollut. A.29(3): 225-233 1982 2019/02/13
甲殻類 Daphnia magna Mortality LC50 48 hours 0.209392 mol/L 17 Aquatic OASIS (OECD QSAR Toolbox) Peter C. von der Ohe, Ralph Kühne, Ralf-Uwe Ebert,
Rolf Altenburger, Matthias Liess, and Gerrit
Schüürmann
Structural Alerts-A New Classification Model to
Discriminate Excess Toxicity from Narcotic
Effect Levels of Organic Compounds in the
Acute Daphnid Assay
Chem. Res. Toxicol., 18 (3) 2005 2019/02/22
甲殻類 Daphnia magna Enzyme(s) (beta-Galactosidase) EC50 0.04 days 0.00109 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Fochtman,P., A. Raszka, and E. Nierzedska The Use of Conventional Bioassays, Microbiotests,
and Some "Rapid" Methods in the Selection of an
Optimal Test Battery for the Assessment of
Pesticides Toxicity
Environ. Toxicol.15(5): 376-384 2000 2019/02/13
甲殻類 Daphnia magna Mortality LC50 21 days 0.008 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., F. Moberts, and G. Niebeek Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. II. Effects on Survival,
Reproduction and Growth of Daphnia magna
Aquat. Toxicol.7:165-175 1988 2019/02/13
甲殻類 others Gammarus pulex Mortality LC50 1 days 4.77 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bluzat,R., O. Jonot, and J. Seuge Acute Toxicity of a Fungicide, Thirame
(Dithiocarbamate) in the Freshwater Amphipodal
Crustacean Gammarus pulex
Environ. Pollut. A.29(3): 225-233 1982 2019/02/13
甲殻類 Daphnia magna Mortality 1 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Jouany,J.M., R. Truhaut, P. Vasseur, D. Klein, J.
F. Ferard, and P. Deschamps
An Example of Interaction between Environmental
Pollutants: Modification of Thiram Toxicity to
Freshwater Organisms by Nitrites or Nitrates
in Relation to Nitrosamine Synthesis
Ecotoxicol. Environ. Saf.9(3): 327-338 1985 2016/03/25
甲殻類 Daphnia magna Mortality NR-ZERO 3.5 hours 9 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Martins,J.C., M.L. Saker, L.F. Oliva Teles, and V.
M. Vasconcelos
Oxygen Consumption by Daphnia magna Straus as a
Marker of Chemical Stress in the Aquatic
Environment
Environ. Toxicol. Chem.26(9): 1987-1991 2007 2025/05/02
甲殻類 Daphnia magna Behavior EC50 0.006 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Knie,J., A. Halke, I. Juhnke, and W. Schiller Results of Studies on Chemical Substances with
Four Biotests (Ergebnisse der Untersuch-Ungen
von Chemischen Stoffen mit vier Biotests)
Dtsch. Gewaesserkd. Mitt.27(3): 77-79 1983 2016/03/25
甲殻類 Daphnia magna Mortality LC50 21 days 8 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., F. Moberts, and G. Niebeek Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. II. Effects on Survival,
Reproduction and Growth of Daphnia magna
Aquat. Toxicol.7:165-175 1988 2016/03/25
甲殻類 Daphnia magna Behavior EC50 1 hours 279 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Fochtman,P., A. Raszka, and E. Nierzedska The Use of Conventional Bioassays, Microbiotests,
and Some "Rapid" Methods in the Selection of an
Optimal Test Battery for the Assessment of
Pesticides Toxicity
Environ. Toxicol.15(5): 376-384 2000 2016/03/25
甲殻類 Daphnia magna Mortality LC50 1 days 30 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kyriakopoulou,K., P. Anastasiadou, and K. Machera Comparative Toxicities of Fungicide and Herbicide
Formulations on Freshwater and Marine Species
Bull. Environ. Contam. Toxicol.82(3): 290-295 2009 2016/03/25
甲殻類 Daphnia magna Physiology NOEL 0.25 hours 9 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Martins,J.C., M.L. Saker, L.F. Oliva Teles, and V.
M. Vasconcelos
Oxygen Consumption by Daphnia magna Straus as a
Marker of Chemical Stress in the Aquatic
Environment
Environ. Toxicol. Chem.26(9): 1987-1991 2007 2016/03/25
甲殻類 Daphnia magna Mortality LC50 1.08 days 1300 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Frear,D.E.H., and J.E. Boyd Use of Daphnia magna for the Microbioassay of
Pesticides. I. Development of Standardized
Techniques for Rearing Daphnia and
Preparation of Dosage-Mortality
Curves for Pesticides
J. Econ. Entomol.60(5): 1228-1236 1967 2016/03/25
甲殻類 Daphnia magna Mortality LC50 2 days 10 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kyriakopoulou,K., P. Anastasiadou, and K. Machera Comparative Toxicities of Fungicide and Herbicide
Formulations on Freshwater and Marine Species
Bull. Environ. Contam. Toxicol.82(3): 290-295 2009 2016/03/25
甲殻類 Daphnia magna Physiology LOEL 3.5 hours 9 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Martins,J.C., M.L. Saker, L.F. Oliva Teles, and V.
M. Vasconcelos
Oxygen Consumption by Daphnia magna Straus as a
Marker of Chemical Stress in the Aquatic
Environment
Environ. Toxicol. Chem.26(9): 1987-1991 2007 2016/03/25
甲殻類 Daphnia magna Mortality NR-LETH 1 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Jouany,J.M., R. Truhaut, P. Vasseur, D. Klein, J.
F. Ferard, and P. Deschamps
An Example of Interaction between Environmental
Pollutants: Modification of Thiram Toxicity to
Freshwater Organisms by Nitrites or Nitrates
in Relation to Nitrosamine Synthesis
Ecotoxicol. Environ. Saf.9(3): 327-338 1985 2025/05/02
甲殻類 Daphnia magna Biochemical EC50 1 hours 1.09 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Fochtman,P., A. Raszka, and E. Nierzedska The Use of Conventional Bioassays, Microbiotests,
and Some "Rapid" Methods in the Selection of an
Optimal Test Battery for the Assessment of
Pesticides Toxicity
Environ. Toxicol.15(5): 376-384 2000 2016/03/25
甲殻類 Daphnia magna Mortality LC50 2 days 210 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., J.L. Maas-Diepeveen, G. Niebeek,
W.H.A. Vergouw, P.S. Griffioen, and M.W.
Luijken
Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. I. Short-Term Toxicity
Tests
Aquat. Toxicol.7(3): 145-164 1985 2016/03/25
甲殻類 Daphnia magna mobility EC50 48 hours 0.38 mg/L 12 ECHA Information on Registered Substances 1 study report 2008
甲殻類 Daphnia magna mobility EC50 48 hours 0.18 mg/L × × 12 ECHA Information on Registered Substances 2 study report 1999
甲殻類 Daphnia magna Behavior/Phototactic response LOEC 3.5 hours 300 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Martins,J., M.L. Soares, M.L. Saker, L.
OlivaTeles, and V.M. Vasconcelos
Phototactic Behavior in Daphnia magna Straus as
an Indicator of Toxicants in the Aquatic
Environment
Ecotoxicol. Environ. Saf.67(3) 2007
甲殻類 Daphnia magna mobility EC50 48 hours >0.1 × × 12 ECHA Information on Registered Substances 2 study report 1999
甲殻類 Daphnia magna Mortality EC50 2 days 139 µg/L 17 Aquatic OASIS (OECD QSAR Toolbox) EFSA doi:10.2903/j.efsa.2017.4700 http://dx.doi.org/10.2903/j.efsa.2017.4700 2017 2023/07/18
甲殻類 Daphnia magna Intoxication EC50 48 hours 0.000000776 mol/L 17 Aquatic OASIS (OECD QSAR Toolbox) Furusjö, E., Andersson, M., Rahmberg, M., Svenson,
A.
Estimating environmentally important properties
of chemicals from the chemical structure
Estimating environmentally important properties
of chemicals from the chemical structure - IVL
Rapport B1517
2003 2023/07/18
甲殻類 Daphnia magna Mortality LC50 48 hours 0.000000871 mol/L 17 Aquatic OASIS (OECD QSAR Toolbox) Peter C. von der Ohe, Ralph Kühne, Ralf-Uwe Ebert,
Rolf Altenburger, Matthias Liess, and Gerrit
Schüürmann
Structural Alerts-A New Classification Model to
Discriminate Excess Toxicity from Narcotic
Effect Levels of Organic Compounds in the
Acute Daphnid Assay
Chem. Res. Toxicol., 18 (3), 536 -555. 2005 2023/07/18
甲殻類 Daphnia magna other: mortality and mobility LC50 48 hours >0.2 × 12 ECHA Information on Registered Substances study report 2008
甲殻類 Daphnia magna mobility NOEC 48 hours 0.14 mg/L 12 ECHA Information on Registered Substances 1 study report 2008
甲殻類 Daphnia magna mobility EC50 48 hours 11 μg/L 12 ECHA Information on Registered Substances 2 study report 1994
甲殻類 Daphnia magna Intoxication EC50 48 hours 0.000776 mmol/L 17 Aquatic OASIS (OECD QSAR Toolbox) Furusjö, E., Andersson, M., Rahmberg, M., Svenson,
A.
Estimating environmentally important properties
of chemicals from the chemical structure
Estimating environmentally important properties
of chemicals from the chemical structure - IVL
Rapport B1517
2003 2023/07/14
甲殻類 Daphnia magna mobility EC50 24 hours 26 μg/L 12 ECHA Information on Registered Substances 2 study report 1994
甲殻類 Daphnia magna mobility EC100 48 hours 1.3 mg/L 12 ECHA Information on Registered Substances 1 study report 2008
甲殻類 Daphnia magna Mortality LC50 48 hours 0.000871 mmol/L 17 Aquatic OASIS (OECD QSAR Toolbox) Peter C. von der Ohe, Ralph Kühne, Ralf-Uwe Ebert,
Rolf Altenburger, Matthias Liess, and Gerrit
Schüürmann
Structural Alerts-A New Classification Model to
Discriminate Excess Toxicity from Narcotic
Effect Levels of Organic Compounds in the
Acute Daphnid Assay
Chem. Res. Toxicol., 18 (3) 2005 2023/07/14
甲殻類 Daphnia magna Mortality/Mortality LC50 48 hours 0.01 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kyriakopoulou,K., P. Anastasiadou, and K. Machera Comparative Toxicities of Fungicide and Herbicide
Formulations on Freshwater and Marine Species
Bull. Environ. Contam. Toxicol.82(3) 2009
甲殻類 Daphnia magna Behavior/Phototactic response LOEC 48 hours 75 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Martins,J., M.L. Soares, M.L. Saker, L.
OlivaTeles, and V.M. Vasconcelos
Phototactic Behavior in Daphnia magna Straus as
an Indicator of Toxicants in the Aquatic
Environment
Ecotoxicol. Environ. Saf.67(3) 2007
甲殻類 Daphnia magna Mortality/Mortality LC50 26 hours 1300 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Frear,D.E.H., and J.E. Boyd Use of Daphnia magna for the Microbioassay of
Pesticides. I. Development of Standardized
Techniques for Rearing Daphnia and
Preparation of Dosage-Mortality Curves
for Pesticides
J. Econ. Entomol.60(5) 1967
甲殻類 Daphnia magna Mortality/Mortality LC50 24 hours 0.03 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kyriakopoulou,K., P. Anastasiadou, and K. Machera Comparative Toxicities of Fungicide and Herbicide
Formulations on Freshwater and Marine Species
Bull. Environ. Contam. Toxicol.82(3) 2009
甲殻類 Daphnia magna Mortality/Mortality NR-LETH 24 hours 1000 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Jouany,J.M., R. Truhaut, P. Vasseur, D. Klein, J.
F. Ferard, and P. Deschamps
An Example of Interaction between Environmental
Pollutants: Modification of Thiram Toxicity to
Freshwater Organisms by Nitrites or Nitrates
in Relation to Nitrosamine Synthesis
Ecotoxicol. Environ. Saf.9(3) 1985 2025/05/02
甲殻類 Americamysis bahia Mortality/Mortality LC50 96 hours 3.36 ppb Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.
1992
甲殻類 Daphnia magna Behavior/Phototactic response NOEC 48 hours 37.5 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Martins,J., M.L. Soares, M.L. Saker, L.
OlivaTeles, and V.M. Vasconcelos
Phototactic Behavior in Daphnia magna Straus as
an Indicator of Toxicants in the Aquatic
Environment
Ecotoxicol. Environ. Saf.67(3) 2007
甲殻類 Daphnia magna Mortality/Mortality LC50 48 hours 210 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., J.L. Maas-Diepeveen, G. Niebeek,
W.H.A. Vergouw, P.S. Griffioen, and M.W.
Luijken
Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. I. Short-Term Toxicity
Tests
Aquat. Toxicol.7(3) 1985
甲殻類 Daphnia magna Behavior/Phototactic response NOEC 3.5 hours 150 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Martins,J., M.L. Soares, M.L. Saker, L.
OlivaTeles, and V.M. Vasconcelos
Phototactic Behavior in Daphnia magna Straus as
an Indicator of Toxicants in the Aquatic
Environment
Ecotoxicol. Environ. Saf.67(3) 2007
甲殻類 Daphnia magna Feeding behavior/Food consumption EC50 1 hours 0.279 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Fochtman,P., A. Raszka, and E. Nierzedska The Use of Conventional Bioassays, Microbiotests,
and Some "Rapid" Methods in the Selection of an
Optimal Test Battery for the Assessment of
Pesticides Toxicity
Environ. Toxicol.15(5) 2000
甲殻類 Crassostrea gigas Intoxication/Immobile NOEL 48 hours <1.3 ppb Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.
1992
甲殻類 Daphnia magna Behavior/Phototactic response LOEC 24 hours 9.38 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Martins,J., M.L. Soares, M.L. Saker, L.
OlivaTeles, and V.M. Vasconcelos
Phototactic Behavior in Daphnia magna Straus as
an Indicator of Toxicants in the Aquatic
Environment
Ecotoxicol. Environ. Saf.67(3) 2007
甲殻類 Americamysis bahia Mortality/Mortality NOEL 96 hours 2.3 ppb Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.
1992
甲殻類 Crassostrea gigas Intoxication/Immobile EC50 48 hours 4.7 ppb Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.
1992
甲殻類 Daphnia magna LC50 48 hours 0.21 mg/L 4 OECD SIDS (HPVC) 3 Van Leeuwen CJ, Maas-Diepeveen JL, Niebeek G,
Vergouwm WHA, Griffioen PS and Luijken MW
Aquatic toxicological aspects of dithiocarbamates
and related compounds. I. Short-term toxicity
test
Aquatic toxicology 1985 2018/12/06
甲殻類 Daphnia magna mobility NOEC 24 hours 0.027 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute immobilisation of Bis
(dimethylthiocarbamoyl) disulfide in Daphnia
magna
2008 2018/12/06
甲殻類 Daphnia magna LOEC 24 hours 0.045 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute immobilisation of Bis
(dimethylthiocarbamoyl) disulfide in Daphnia
magna
2008 2018/12/06
甲殻類 Daphnia magna mobility EC50 24 hours 0.108 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute immobilisation of Bis
(dimethylthiocarbamoyl) disulfide in Daphnia
magna
2008 2018/12/06
甲殻類 Daphnia magna mobility EC100 48 hours 1.3 mg/L 12 ECHA Information on Registered Substances 1 study report 2008 2016/03/18
甲殻類 Daphnia magna mobility EC50 48 hours 0.18 mg/L 12 ECHA Information on Registered Substances 2 study report 1999 2016/03/18
甲殻類 Daphnia magna Intoxication ET50 48 hours 0.187 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Furusjö, E., Andersson, M., Rahmberg, M., Svenson,
A.
Estimating environmentally important properties
of chemicals from the chemical structure
2003 2016/02/08
甲殻類 Daphnia magna mobility EC50 24 hours 26 μg/L 12 ECHA Information on Registered Substances 2 study report 1994 2016/03/18
甲殻類 Daphnia magna mobility EC50 48 hours 11 μg/L 12 ECHA Information on Registered Substances 2 study report 1994 2016/03/18
甲殻類 Daphnia magna mortality and mobility LC50 48 hours >0.2 mg/L × 12 ECHA Information on Registered Substances study report 2008 2023/07/12
甲殻類 Daphnia magna mobility EC50 48 hours 0.38 mg/L 12 ECHA Information on Registered Substances 1 study report 2008 2016/03/18
甲殻類 Daphnia magna mobility EC50 48 hours >0.1 mg/L 12 ECHA Information on Registered Substances 2 study report 1999 2016/03/27
甲殻類 Daphnia magna mortality and mobility LC50 14 days >86 μg/L × 12 ECHA Information on Registered Substances study report 2008 2016/03/18
甲殻類 Daphnia magna Mortality LC50 48 hours 0.209 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Peter C. von der Ohe, Ralph Kühne, Ralf-Uwe Ebert,
Rolf Altenburger, Matthias Liess, and Gerrit
Schüürmann
Structural Alerts-A New Classification Model to
Discriminate Excess Toxicity from Narcotic
Effect Levels of Organic Compounds in the
Acute Daphnid Assay
2005 2016/02/08
甲殻類 Daphnia magna mobility EC50 48 hours 0.036 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute immobilisation of Bis
(dimethylthiocarbamoyl) disulfide in Daphnia
magna
2008 2018/12/06
甲殻類 Daphnia magna breakdown products LC50 48 hours 0.21 mg/L 10 EHC (Environmental Health Criteria) VAN LEEUWEN, C.J. Ecotoxicological aspects of dithiocarbamates Utrecht, University of Utrecht (Thesis). 1986 2018/12/13
甲殻類 Daphnia magna mobility EC50 24 hours 0.108 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute immobilisation of Bis
(dimethylthiocarbamoyl) disulfide in Daphnia
magna
2008 2018/12/06
甲殻類 Daphnia magna mobility EC50 48 hours 0.036 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute immobilisation of Bis
(dimethylthiocarbamoyl) disulfide in Daphnia
magna
2008 2018/12/06
甲殻類 Daphnia magna 遊泳阻害 48 hours 250 μg/L 2 日本環境省 農薬登録保留基準(水産動植物) 2018/12/18
甲殻類 Daphnia magna mobility LOEC 48 hours 0.027 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute immobilisation of Bis
(dimethylthiocarbamoyl) disulfide in Daphnia
magna
2008 2018/12/06
甲殻類 Daphnia magna mobility LOEC 48 hours 0.027 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute immobilisation of Bis
(dimethylthiocarbamoyl) disulfide in Daphnia
magna
2008 2018/12/06
甲殻類 Daphnia magna mobility NOEC 24 hours 0.027 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute immobilisation of Bis
(dimethylthiocarbamoyl) disulfide in Daphnia
magna
2008 2018/12/06
甲殻類 Daphnia magna LC50 48 hours 0.21 mg/L 4 OECD SIDS (HPVC) 3 Van Leeuwen CJ, Maas-Diepeveen JL, Niebeek G,
Vergouwm WHA, Griffioen PS and Luijken MW
Aquatic toxicological aspects of dithiocarbamates
and related compounds. I. Short-term toxicity
test
Aquatic toxicology 1985 2018/12/06
甲殻類 Daphnia magna LOEC 24 hours 0.045 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute immobilisation of Bis
(dimethylthiocarbamoyl) disulfide in Daphnia
magna
2008 2018/12/06
甲殻類 Daphnia magna Mortality LC50 2 days 210 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
b Van Leeuwen, C.J., J.L. Maas-Diepeveen, G.
Niebeek, W.H.A. Vergouw, P.S. Griffioen, and M.W.
Luijken
Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. I. Short-Term Toxicity
Tests.
Aquat.Toxicol. 1985 2016/03/07
甲殻類 Daphnia magna mobility EC50 48 hours 139 μg/L meas. (arithm. mean) test mat. 12 ECHA Information on Registered Substances 1 study report 2015 2023/08/04
甲殻類 Daphnia magna mobility NOEC 48 hours 50 μg/L meas. (arithm. mean) test mat. 12 ECHA Information on Registered Substances 1 study report 2015 2023/08/04
甲殻類 Daphnia magna mobility EC50 48 hours 0.18 mg/L × 12 ECHA Information on Registered Substances 2 study report Unnamed 1999 2019/02/20
甲殻類 Daphnia magna mobility EC50 48 hours >0.1 mg/L × 12 ECHA Information on Registered Substances 2 study report Unnamed 1999 2019/02/20
甲殻類 Crassostrea gigas EC50 48 hours 4.7 ppb 3 USEPA Pesticide Ecotoxicity Database B. Montague ICI Plant Protection Division, England 1992 2019/02/27
甲殻類 Mysidopsis bahia LC50 96 hours 3.36 ppb 3 USEPA Pesticide Ecotoxicity Database B. Montague ICI Plant Protection Division, England 1992 2019/02/27
甲殻類 Mysidopsis bahia LC50 96 hours 2.3 ppb 3 USEPA Pesticide Ecotoxicity Database B. Montague ICI Plant Protection Division, England 1992 2019/02/27
甲殻類 Daphnia magna mobility EC50 24 hours 0.108 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute immobilisation of Bis
(dimethylthiocarbamoyl) disulfide in Daphnia
magna
2008 2016/02/22
甲殻類 Daphnia magna LC50 48 hours 0.21 mg/L 4 OECD SIDS (HPVC) 3 Van Leeuwen CJ, Maas-Diepeveen JL, Niebeek G,
Vergouwm WHA, Griffioen PS and Luijken MW
Aquatic toxicological aspects of dithiocarbamates
and related compounds. I. Short-term toxicity
test
Aquatic toxicology 1985 2016/02/22
甲殻類 Daphnia magna 遊泳阻害 EC50 48 hours 250 μg/L 2 日本環境省 農薬登録保留基準(水産動植物) 環境省 水産動植物の被害防止に係る農薬登録保留基準の設定に関する資料 2016/02/17
甲殻類 Daphnia magna LC50 48 hours 0.21 mg/L 10 EHC (Environmental Health Criteria) VAN LEEUWEN, C.J. Ecotoxicological aspects of dithiocarbamates Utrecht, University of Utrecht (Thesis) 2016/03/06
甲殻類 Daphnia magna mobility EC50 48 hours 0.036 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute immobilisation of Bis
(dimethylthiocarbamoyl) disulfide in Daphnia
magna
2008 2016/02/22
甲殻類 Daphnia magna reproduction NOEC 21 days 40 μg/L 12 ECHA Information on Registered Substances 1 study report 2008
甲殻類 Daphnia magna Growth NOEC 21 days 20 µg/L 17 Aquatic OASIS (OECD QSAR Toolbox) EFSA doi:10.2903/j.efsa.2017.4700 http://dx.doi.org/10.2903/j.efsa.2017.4700 2017 2023/07/18
甲殻類 Daphnia magna mortality EC50 21 days 57 μg/L 12 ECHA Information on Registered Substances 1 study report 2008
甲殻類 Daphnia magna reproduction EC50 21 days 70 μg/L 12 ECHA Information on Registered Substances 1 study report 2008
甲殻類 Daphnia magna mortality NOEC 21 days 40 μg/L 12 ECHA Information on Registered Substances 1 study report 2008
甲殻類 Daphnia magna other: growth and sub-lethal effects NOEC 21 days 20 μg/L 12 ECHA Information on Registered Substances 1 study report 2008
甲殻類 Daphnia magna mortality and mobility LC50 14 days 86 μg/L nominal, act.ingr. × 12 ECHA Information on Registered Substances study report 2008 2020/03/18
甲殻類 Daphnia magna Mortality/Mortality LC50 21 days 8 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., F. Moberts, and G. Niebeek Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. II. Effects on Survival,
Reproduction and Growth of Daphnia magna
Aquat. Toxicol.7 1988
甲殻類 Daphnia magna reproduction EC50 21 days 70 μg/L 12 ECHA Information on Registered Substances 1 study report 2008 2016/03/18
甲殻類 Daphnia magna mobility 48 hours 0.14 mg/L 12 ECHA Information on Registered Substances 1 study report 2008 2016/03/18
甲殻類 Daphnia magna reproduction NOEC 21 days 40 μg/L 12 ECHA Information on Registered Substances 1 study report 2008 2023/07/12
甲殻類 Daphnia magna EGGHATCH, SURVIVE, GROWTH NOEL 21 days 20 μg/L 3 USEPA Pesticide Ecotoxicity Database E. Arnold 2015 2016/02/02
甲殻類 Daphnia magna growth and sub-lethal effects NOEC 21 days 20 μg/L 12 ECHA Information on Registered Substances 1 study report 2008 2023/07/12
甲殻類 Daphnia magna mortality EC50 21 days 57 μg/L 12 ECHA Information on Registered Substances 1 study report 2008 2016/03/18
甲殻類 Daphnia magna mortality NOEC 21 days 40 μg/L 12 ECHA Information on Registered Substances 1 study report 2008 2023/07/12
甲殻類 Daphnia magna EGGHATCH, SURVIVE, GROWTH LOEC 21 days 40 μg/L 3 USEPA Pesticide Ecotoxicity Database E. Arnold 2015 2016/02/02
甲殻類 Daphnia magna LC50 21 days 0.008 mg/L 4 OECD SIDS (HPVC) 4 Van Leeuwen CJ, Moberts F and Niebeek G Aquatic toxicological aspects of dithiocarbamatrs
and related compounds. II. Effects on survival,
reproduction and growth of Daphnia magna
Aquatic toxicology 1985 2018/12/06
甲殻類 Daphnia magna LC50 21 days 0.008 mg/L 4 OECD SIDS (HPVC) 4 Van Leeuwen CJ, Moberts F and Niebeek G Aquatic toxicological aspects of dithiocarbamatrs
and related compounds. II. Effects on survival,
reproduction and growth of Daphnia magna
Aquatic toxicology 1985 2018/12/06
甲殻類 Daphnia magna EGGHATCH, SURVIVE, GROWTH NOEL 21 days 20 ppb 3 USEPA Pesticide Ecotoxicity Database E. Arnold 2015 2018/03/07
甲殻類 Daphnia magna Mortality LC50 21 days 8 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
b Van Leeuwen, C.J., F. Moberts, and G. Niebeek Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. II. Effects on Survival,
Reproduction and Growth of Daphnia magna.
Aquat.Toxicol. 1985 2016/03/07
甲殻類 Crassostrea gigas NOEL 48 hours <1.3 ppb 3 USEPA Pesticide Ecotoxicity Database B. Montague ICI Plant Protection Division, England 1992 2019/02/27
甲殻類 Daphnia magna EGGHATCH, SURVIVE, GROWTH LOEC 21 days 40 ppb 3 USEPA Pesticide Ecotoxicity Database E. Arnold 2015 2018/03/07
甲殻類 Daphnia magna LC50 21 days 0.008 mg/L 4 OECD SIDS (HPVC) 4 Van Leeuwen CJ, Moberts F and Niebeek G Aquatic toxicological aspects of dithiocarbamatrs
and related compounds. II. Effects on survival,
reproduction and growth of Daphnia magna
Aquatic toxicology 1985 2016/02/22
甲殻類 Daphnia magna LOEC 24 hours 0.045 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute immobilisation of Bis
(dimethylthiocarbamoyl) disulfide in Daphnia
magna
2008 2016/02/22
甲殻類 Daphnia magna mobility LOEC 48 hours 0.027 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute immobilisation of Bis
(dimethylthiocarbamoyl) disulfide in Daphnia
magna
2008 2016/02/22
甲殻類 Daphnia magna mobility NOEC 24 hours 0.027 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute immobilisation of Bis
(dimethylthiocarbamoyl) disulfide in Daphnia
magna
2008 2016/02/22
魚類 Danio rerio Mortality/Mortality NR-LETH 24 hours 1000 μg/L Formulation × 16 ECOTOX Jouany,J.M., R. Truhaut, P. Vasseur, D. Klein, J.
F. Ferard, and P. Deschamps
An Example of Interaction between Environmental
Pollutants: Modification of Thiram Toxicity to
Freshwater Organisms by Nitrites or Nitrates
in Relation to Nitrosamine Synthesis
Ecotoxicol. Environ. Saf.9(3): 1985 2023/07/14
魚類 Pimephales promelas Mortality/Survival NOEC 210 days 1.1 ppb Active ingredient 16 ECOTOX U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2023/07/14
魚類 Oncorhynchus mykiss mortality (fish) LC50 96 hours 0.046 mg/L meas. (initial) act. ingr. 12 ECHA Information on Registered Substances 2 study report 2000 2023/12/21
魚類 Danio rerio Mortality/Mortality LC50 116 hours ca.50 μM Formulation × 16 ECOTOX Truong,L., S.M. Bugel, A. Chlebowski, C.Y. Usenko,
M.T. Simonich, S.L.M. Simonich, and R.L.
Tanguay
Optimizing Multi-Dimensional High Throughput
Screening Using Zebrafish
Reprod. Toxicol.10(65): 2016 2023/07/14
魚類 Lepomis macrochirus Mortality/Mortality LC50 96 hours 42 ppb Active ingredient 16 ECOTOX U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2023/07/14
魚類 Pimephales promelas mortality and growth NOEC 33 days 4.6 μg/L meas. (arithm. mean) act. ingr. 12 ECHA Information on Registered Substances 1 study report 2008 2023/12/21
魚類 Danio rerio Development/Deformation LOEL 20 hours 4 ppb Formulation × 16 ECOTOX Tilton,F., J.K. La Du, M. Vue, N. Alzarban, and R.
L. Tanguay
Dithiocarbamates have a Common Toxic Effect on
Zebrafish Body Axis Formation
Toxicol. Appl. Pharmacol.216(1): 2006 2023/07/14
魚類 Danio rerio Mortality/Mortality LC50 116 hours ca.15 μM Formulation × 16 ECOTOX Truong,L., S.M. Bugel, A. Chlebowski, C.Y. Usenko,
M.T. Simonich, S.L.M. Simonich, and R.L.
Tanguay
Optimizing Multi-Dimensional High Throughput
Screening Using Zebrafish
Reprod. Toxicol.10(65): 2016 2023/07/14
魚類 Oncorhynchus mykiss Mortality/Mortality LOEC 60 days 1 μg/L Active ingredient × 16 ECOTOX Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3): 1986 2023/07/14
魚類 Cyprinodon variegatus Mortality/Mortality NOEL 96 hours 0.09 ppm Active ingredient 16 ECOTOX U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2023/07/14
魚類 Lepomis macrochirus mortality (fish) LC50 96 hours 0.13 mg/L nominal act. ingr. × 12 ECHA Information on Registered Substances 3 study report 1983 2023/12/21
魚類 Danio rerio Mortality/Mortality NR-LETH 20 hours 0.9~50 μM Active ingredient × 16 ECOTOX Raftery,T.D., G.M. Isales, K.L. Yozzo, and D.C.
Volz
High-Content Screening Assay for Identification
of Chemicals Impacting Spontaneous Activity in
Zebrafish Embryos
Environ. Sci. Technol.48(1): 2014 2023/07/14
魚類 Lepomis macrochirus mortality (fish) NOEC 96 hours <0.056 nominal act. ingr. × 12 ECHA Information on Registered Substances 3 study report 1983 2023/12/21
魚類 Oncorhynchus mykiss Mortality/Mortality LC50 24 hours 300 μg/L Active ingredient × 16 ECOTOX Van Leeuwen,C.J., J.L. Maas-Diepeveen, and H.C.M.
Overbeek
Sublethal Effects of Tetramethylthiuram Disulfide
(Thiram) in Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(1): 1986 2023/07/14
魚類 Lepomis macrochirus Mortality/Mortality LC50 96 hours 0.28 ppm Formulation 16 ECOTOX U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2023/07/14
魚類 Danio rerio Mortality/Mortality LC50 20 hours 40~400 ppb Formulation × 16 ECOTOX Tilton,F., J.K. La Du, M. Vue, N. Alzarban, and R.
L. Tanguay
Dithiocarbamates have a Common Toxic Effect on
Zebrafish Body Axis Formation
Toxicol. Appl. Pharmacol.216(1): 2006 2023/07/14
魚類 Pimephales promelas Reproduction/Progeny counts/numbers NOEC 210 days 1.1 ppb Active ingredient 16 ECOTOX U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2023/07/14
魚類 Lepomis macrochirus Mortality/Mortality LC50 96 hours 280 ppb Formulation 16 ECOTOX U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2023/07/14
魚類 Oncorhynchus mykiss (Rainbow trout) growth rate NOEC 42 days 0.012 mg/L 12 ECHA Information on Registered Substances 1 study report 2001
魚類 Oncorhynchus mykiss (Rainbow trout) mortality NOEC 42 days 0.02 mg/L 12 ECHA Information on Registered Substances 1 study report 2001
魚類 Danio rerio (Zebrafish) Development/Deformation LOEC 117 hours 7.5 nM Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Boxtel,A.L., J.H. Kamstra, D.M. Fluitsma, and
J. Legler
Dithiocarbamates are Teratogenic to Developing
Zebrafish Through Inhibition of Lysyl Oxidase
Activity
Toxicol. Appl. Pharmacol.244(2) 2010
魚類 Danio rerio (Zebrafish) Growth/Area NOEC 20 hours 90 nM Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Raftery,T.D., G.M. Isales, K.L. Yozzo, and D.C.
Volz
High-Content Screening Assay for Identification
of Chemicals Impacting Spontaneous Activity in
Zebrafish Embryos
Environ. Sci. Technol.48(1) 2014
魚類 Danio rerio (Zebrafish) Development/Deformation NOEL 20 hours <4 ppb Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Tilton,F., J.K. La Du, M. Vue, N. Alzarban, and R.
L. Tanguay
Dithiocarbamates have a Common Toxic Effect on
Zebrafish Body Axis Formation
Toxicol. Appl. Pharmacol.216(1) 2006
魚類 Oncorhynchus mykiss (Rainbow trout) growth rate LOEC 28 days 0.02 mg/L nominal, act.ingr. 12 ECHA Information on Registered Substances 1 study report 2001 2020/03/18
魚類 Pimephales promelas (Fathead minnow) Mortality/Survival LOEC 210 days 2.2 ppb Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.
1992
魚類 Danio rerio (Zebrafish) Development/Deformation LOEL 20 hours 4 ppb Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Tilton,F., J.K. La Du, M. Vue, N. Alzarban, and R.
L. Tanguay
Dithiocarbamates have a Common Toxic Effect on
Zebrafish Body Axis Formation
Toxicol. Appl. Pharmacol.216(1) 2006
魚類 Pimephales promelas (Fathead minnow) Reproduction/ Progeny counts/numbers LOEC 210 days 2.2 ppb Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.
1992
魚類 Oncorhynchus mykiss (Rainbow trout) Growth/Growth, general LOEC 60 days 0.56 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3) 1986
魚類 Danio rerio (Zebrafish) Mortality/Mortality LOEC 7 days 1 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., E.M.M. Grootelaar, and G.
Niebeek
Fish Embryos as Teratogenicity Screens: A
Comparison of Embryotoxicity Between Fish and
Birds
Ecotoxicol. Environ. Saf.20(1) 1990
魚類 Danio rerio (Zebrafish) Mortality/Mortality NR-LETH 20 hours 0.9~50 μM Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Raftery,T.D., G.M. Isales, K.L. Yozzo, and D.C.
Volz
High-Content Screening Assay for Identification
of Chemicals Impacting Spontaneous Activity in
Zebrafish Embryos
Environ. Sci. Technol.48(1) 2014 2025/05/02
魚類 Danio rerio (Zebrafish) Mortality/Mortality LC50 20 hours 40~400 ppb Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Tilton,F., J.K. La Du, M. Vue, N. Alzarban, and R.
L. Tanguay
Dithiocarbamates have a Common Toxic Effect on
Zebrafish Body Axis Formation
Toxicol. Appl. Pharmacol.216(1) 2006
魚類 Oncorhynchus mykiss (Rainbow trout) Multiple/Multiple effects reported as
one result
EC50 60 days 0.64 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3) 1986
魚類 Danio rerio (Zebrafish) Mortality/Mortality NR-LETH 24 hours 1000 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Jouany,J.M., R. Truhaut, P. Vasseur, D. Klein, J.
F. Ferard, and P. Deschamps
An Example of Interaction between Environmental
Pollutants: Modification of Thiram Toxicity to
Freshwater Organisms by Nitrites or Nitrates
in Relation to Nitrosamine Synthesis
Ecotoxicol. Environ. Saf.9(3) 1985 2025/05/02
魚類 Danio rerio (Zebrafish) Development/Deformation EC50 120 hours 50 nM Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Boxtel,A.L., B. Pieterse, P. Cenijn, J.H.
Kamstra, A. Brouwer, W. Van Wieringen, J. De
Boer, and J. Legler
Dithiocarbamates Induce Craniofacial
Abnormalities and Downregulate sox9a During
Zebrafish Development
Toxicol. Sci.117(1) 2010
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality/Mortality LC50 60 days 1.1 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3) 1986
魚類 Danio rerio (Zebrafish) Mortality/Mortality LC50 116 hours 15 μM Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Truong,L., S.M. Bugel, A. Chlebowski, C.Y. Usenko,
M.T. Simonich, S.L.M. Simonich, and R.L.
Tanguay
Optimizing Multi-Dimensional High Throughput
Screening Using Zebrafish
Reprod. Toxicol.10(65) 2016
魚類 Danio rerio (Zebrafish) Mortality/Mortality LC50 20 hours 14 μM Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Raftery,T.D., G.M. Isales, K.L. Yozzo, and D.C.
Volz
High-Content Screening Assay for Identification
of Chemicals Impacting Spontaneous Activity in
Zebrafish Embryos
Environ. Sci. Technol.48(1) 2014
魚類 Danio rerio (Zebrafish) Mortality/Mortality LC50 116 hours 50 μM Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Truong,L., S.M. Bugel, A. Chlebowski, C.Y. Usenko,
M.T. Simonich, S.L.M. Simonich, and R.L.
Tanguay
Optimizing Multi-Dimensional High Throughput
Screening Using Zebrafish
Reprod. Toxicol.10(65) 2016
魚類 Danio rerio (Zebrafish) Multiple/Multiple effects reported as
one result
EC50 120 hours <0.0014 μM Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Padilla,S., D. Corum, B. Padnos, D.L. Hunter, A.
Beam, K.A. Houck, N. Sipes, N. Kleinstreuer, T.
Knudsen, D.J. Dix, and
Zebrafish Developmental Screening of the ToxCast
Phase I Chemical Library
Reprod. Toxicol.33(2) 2012
魚類 Danio rerio (Zebrafish) Mortality/Mortality LC50 7 days 34 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., E.M.M. Grootelaar, and G.
Niebeek
Fish Embryos as Teratogenicity Screens: A
Comparison of Embryotoxicity Between Fish and
Birds
Ecotoxicol. Environ. Saf.20(1) 1990
魚類 Danio rerio (Zebrafish) Multiple/Multiple effects reported as
one result
LOEC 7 days 1 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., E.M.M. Grootelaar, and G.
Niebeek
Fish Embryos as Teratogenicity Screens: A
Comparison of Embryotoxicity Between Fish and
Birds
Ecotoxicol. Environ. Saf.20(1) 1990
魚類 Oncorhynchus mykiss (Rainbow trout) Multiple/Multiple effects reported as
one result
LOEC 60 days <=0.32 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3) 1986
魚類 Oncorhynchus mykiss (Rainbow trout) Growth/Growth, general LOEC 60 days <=0.32 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3) 1986
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality/Mortality LOEC 60 days 1 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3) 1986
魚類 Danio rerio (Zebrafish) Behavior/Activity, general NOEC 20 hours 0.18~90 nM Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Raftery,T.D., G.M. Isales, K.L. Yozzo, and D.C.
Volz
High-Content Screening Assay for Identification
of Chemicals Impacting Spontaneous Activity in
Zebrafish Embryos
Environ. Sci. Technol.48(1) 2014
魚類 Pimephales promelas (Fathead minnow) Reproduction/ Progeny counts/numbers NOEC 210 days 1.1 ppb Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.
1992
魚類 Pimephales promelas (Fathead minnow) Mortality/Survival NOEC 210 days 1.1 ppb Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.
1992
魚類 Danio rerio (Zebrafish) Development/Teratogenic measurements EC50 7 days 6 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., E.M.M. Grootelaar, and G.
Niebeek
Fish Embryos as Teratogenicity Screens: A
Comparison of Embryotoxicity Between Fish and
Birds
Ecotoxicol. Environ. Saf.20(1) 1990
魚類 Danio rerio Development/Teratogenic measurements LOEC 7 days 0.001 mg/L Active ingredient × 16 ECOTOX Van Leeuwen,C.J., E.M.M. Grootelaar, and G.
Niebeek
Fish Embryos as Teratogenicity Screens: A
Comparison of Embryotoxicity Between Fish and
Birds
Ecotoxicol. Environ. Saf.20(1): 1990 2023/07/14
魚類 Oncorhynchus mykiss Multiple/Multiple effects reported as
one result
EC50 60 days 0.64 μg/L Active ingredient × 16 ECOTOX Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3): 1986 2023/07/14
魚類 Pimephales promelas number hatched NOEC 33 days >9.3 μg/L meas. (arithm. mean) act. ingr. 12 ECHA Information on Registered Substances 1 study report 2008 2023/12/21
魚類 Danio rerio Mortality/Mortality LC50 20 hours 14 μM Active ingredient × 16 ECOTOX Raftery,T.D., G.M. Isales, K.L. Yozzo, and D.C.
Volz
High-Content Screening Assay for Identification
of Chemicals Impacting Spontaneous Activity in
Zebrafish Embryos
Environ. Sci. Technol.48(1): 2014 2023/07/14
魚類 Danio rerio Development/Deformation LOEC 117 hours 7.5 nM Active ingredient × 16 ECOTOX Van Boxtel,A.L., J.H. Kamstra, D.M. Fluitsma, and
J. Legler
Dithiocarbamates are Teratogenic to Developing
Zebrafish Through Inhibition of Lysyl Oxidase
Activity
Toxicol. Appl. Pharmacol.244(2): 2010 2023/07/14
魚類 Oncorhynchus mykiss mortality (fish) NOEC 96 hours 0.01 mg/L meas. (initial) act. ingr. 12 ECHA Information on Registered Substances 2 study report 2000 2023/12/21
魚類 Oncorhynchus mykiss growth rate NOEC 42 days 0.012 mg/L nominal act. ingr. 12 ECHA Information on Registered Substances 2 study report 2001 2023/12/21
魚類 Pimephales promelas mortality and growth LOEC 33 days 9.3 μg/L meas. (arithm. mean) act. ingr. 12 ECHA Information on Registered Substances 1 study report 2008 2023/12/21
魚類 Pimephales promelas mortality (fish) NOEC 96 hours 0.1 mg/L nominal act. ingr. × 12 ECHA Information on Registered Substances 3 study report 1983 2023/12/21
魚類 Oncorhynchus mykiss Multiple/Multiple effects reported as
one result
LOEC 60 days <=0.32 μg/L Active ingredient × 16 ECOTOX Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3): 1986 2023/07/14
魚類 Oncorhynchus mykiss Mortality/Mortality LC50 48 hours 400 ppb Formulation 16 ECOTOX U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2023/07/14
魚類 Oncorhynchus mykiss Growth/Growth, general LOEC 60 days <=0.32 μg/L Active ingredient × 16 ECOTOX Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3): 1986 2023/07/14
魚類 Danio rerio Development/Teratogenic measurements EC50 7 days 0.006 mg/L Active ingredient × 16 ECOTOX Van Leeuwen,C.J., E.M.M. Grootelaar, and G.
Niebeek
Fish Embryos as Teratogenicity Screens: A
Comparison of Embryotoxicity Between Fish and
Birds
Ecotoxicol. Environ. Saf.20(1): 1990 2023/07/14
魚類 Oncorhynchus mykiss Mortality/Mortality LC50 96 hours 130 ppb Active ingredient 16 ECOTOX U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2023/07/14
魚類 Oncorhynchus mykiss Mortality/Mortality LC50 96 hours 0.27 μM Active ingredient × 16 ECOTOX Greene,M.W., and R.M. Kocan Toxicological Mechanisms of a Multicomponent
Agricultural Seed Protectant in the Rainbow
Trout (Oncorhynchus mykiss) and Fathead
Minnow (Pimephales promelas)
Can. J. Fish. Aquat. Sci.54: 1997 2023/07/14
魚類 Pimephales promelas Mortality/Mortality LC50 96 hours 148 nM Active ingredient × 16 ECOTOX Greene,M.W., and R.M. Kocan Toxicological Mechanisms of a Multicomponent
Agricultural Seed Protectant in the Rainbow
Trout (Oncorhynchus mykiss) and Fathead
Minnow (Pimephales promelas)
Can. J. Fish. Aquat. Sci.54: 1997 2023/07/14
魚類 Pimephales promelas Mortality/Survival LOEC 210 days 2.2 ppb Active ingredient 16 ECOTOX U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2023/07/14
魚類 Oncorhynchus mykiss Growth/Growth, general LOEC 60 days 0.56 μg/L Active ingredient × 16 ECOTOX Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3): 1986 2023/07/14
魚類 Oncorhynchus mykiss growth rate LOEC 28 days 0.02 mg/L nominal act. ingr. 12 ECHA Information on Registered Substances 2 study report 2001 2023/12/21
魚類 Cyprinodon variegatus mortality (fish) LC50 96 hours 0.54 mg/L meas. (arithm. mean) act. ingr. 12 ECHA Information on Registered Substances 1 study report 1992 2023/12/21
魚類 Danio rerio Development/Deformation EC50 120 hours 50 nM Active ingredient × 16 ECOTOX Van Boxtel,A.L., B. Pieterse, P. Cenijn, J.H.
Kamstra, A. Brouwer, W. Van Wieringen, J. De
Boer, and J. Legler
Dithiocarbamates Induce Craniofacial
Abnormalities and Downregulate sox9a During
Zebrafish Development
Toxicol. Sci.117(1): 2010 2023/07/14
魚類 Danio rerio Mortality/Mortality LOEC 7 days 0.001 mg/L Active ingredient × 16 ECOTOX Van Leeuwen,C.J., E.M.M. Grootelaar, and G.
Niebeek
Fish Embryos as Teratogenicity Screens: A
Comparison of Embryotoxicity Between Fish and
Birds
Ecotoxicol. Environ. Saf.20(1): 1990 2023/07/14
魚類 Danio rerio Multiple/Multiple effects reported as
one result
EC50 120 hours <0.0014 μM Formulation × 16 ECOTOX Padilla,S., D. Corum, B. Padnos, D.L. Hunter, A.
Beam, K.A. Houck, N. Sipes, N. Kleinstreuer, T.
Knudsen, D.J. Dix, and
Zebrafish Developmental Screening of the ToxCast
Phase I Chemical Library
Reprod. Toxicol.33(2): 2012 2023/07/14
魚類 Pimephales promelas mortality (fish) LC50 96 hours 0.27 mg/L nominal act. ingr. × 12 ECHA Information on Registered Substances 3 study report 1983 2023/12/21
魚類 Lepomis macrochirus Mortality/Mortality NOEL 96 hours 0.1 ppm Formulation 16 ECOTOX U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2023/07/14
魚類 Oncorhynchus mykiss mortality NOEC 42 days 0.02 mg/L nominal act. ingr. 12 ECHA Information on Registered Substances 2 study report 2001 2023/12/21
魚類 Danio rerio Growth/Area NOEC 20 hours 90 nM Active ingredient × 16 ECOTOX Raftery,T.D., G.M. Isales, K.L. Yozzo, and D.C.
Volz
High-Content Screening Assay for Identification
of Chemicals Impacting Spontaneous Activity in
Zebrafish Embryos
Environ. Sci. Technol.48(1): 2014 2023/07/14
魚類 Pimephales promelas Mortality/Mortality LC50 96 hours 54.9 nM Active ingredient × 16 ECOTOX Greene,M.W., and R.M. Kocan Toxicological Mechanisms of a Multicomponent
Agricultural Seed Protectant in the Rainbow
Trout (Oncorhynchus mykiss) and Fathead
Minnow (Pimephales promelas)
Can. J. Fish. Aquat. Sci.54: 1997 2023/07/14
魚類 Poecilia reticulata Mortality/Mortality LC50 96 hours 270 μg/L Active ingredient × 16 ECOTOX Van Leeuwen,C.J., J.L. Maas-Diepeveen, G. Niebeek,
W.H.A. Vergouw, P.S. Griffioen, and M.W.
Luijken
Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. I. Short-Term Toxicity
Tests
Aquat. Toxicol.7(3): 1985 2023/07/14
魚類 Oncorhynchus mykiss Mortality/Mortality LC50 24 hours 260 μg/L Active ingredient × 16 ECOTOX Van Leeuwen,C.J., J.L. Maas-Diepeveen, and H.C.M.
Overbeek
Sublethal Effects of Tetramethylthiuram Disulfide
(Thiram) in Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(1): 1986 2023/07/14
魚類 Danio rerio Mortality/Mortality LC50 7 days 0.034 mg/L Active ingredient × 16 ECOTOX Van Leeuwen,C.J., E.M.M. Grootelaar, and G.
Niebeek
Fish Embryos as Teratogenicity Screens: A
Comparison of Embryotoxicity Between Fish and
Birds
Ecotoxicol. Environ. Saf.20(1): 1990 2023/07/14
魚類 Cyprinodon variegatus Mortality/Mortality LC50 96 hours 0.54 ppm Active ingredient 16 ECOTOX U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2023/07/14
魚類 Danio rerio Development/Deformation NOEL 20 hours <4 ppb Formulation × 16 ECOTOX Tilton,F., J.K. La Du, M. Vue, N. Alzarban, and R.
L. Tanguay
Dithiocarbamates have a Common Toxic Effect on
Zebrafish Body Axis Formation
Toxicol. Appl. Pharmacol.216(1): 2006 2023/07/14
魚類 Cyprinodon variegatus mortality (fish) NOEC 96 hours 0.09 mg/L meas. (arithm. mean) act. ingr. 12 ECHA Information on Registered Substances 1 study report 1992 2023/12/21
魚類 Pimephales promelas Reproduction/Progeny counts/numbers LOEC 210 days 2.2 ppb Active ingredient 16 ECOTOX U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2023/07/14
魚類 Danio rerio Behavior/Activity, general NOEC 20 hours 0.18~90 nM Active ingredient × 16 ECOTOX Raftery,T.D., G.M. Isales, K.L. Yozzo, and D.C.
Volz
High-Content Screening Assay for Identification
of Chemicals Impacting Spontaneous Activity in
Zebrafish Embryos
Environ. Sci. Technol.48(1): 2014 2023/07/14
魚類 Oncorhynchus mykiss Mortality/Mortality LC50 96 hours 48 μg/L Formulation 16 ECOTOX Kikuchi,M., T. Miyagaki, and M. Wakabayashi Evaluation of Pesticides Used in Golf Links by
Acute Toxicity Test on Rainbow Trout
Nippon Suisan Gakkaishi62(3): 1996 2023/07/14
魚類 Oncorhynchus mykiss Mortality/Mortality LC50 60 days 1.1 μg/L Active ingredient × 16 ECOTOX Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3): 1986 2023/07/14
魚類 Oncorhynchus mykiss Mortality/Mortality LC50 96 hours 0.26 μM Active ingredient × 16 ECOTOX Greene,M.W., and R.M. Kocan Toxicological Mechanisms of a Multicomponent
Agricultural Seed Protectant in the Rainbow
Trout (Oncorhynchus mykiss) and Fathead
Minnow (Pimephales promelas)
Can. J. Fish. Aquat. Sci.54: 1997 2023/07/14
魚類 Danio rerio (Zebrafish) Mortality LC50 0.83 days mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Tilton,F., J.K. La Du, M. Vue, N. Alzarban, and R.
L. Tanguay
Dithiocarbamates have a Common Toxic Effect on
Zebrafish Body Axis Formation
Toxicol. Appl. Pharmacol.216(1): 55-68 2006 2019/02/13
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality LC50 4 days 0.54 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 60 days 0.0011 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3): 129-145 1986 2019/02/13
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 4 days 0.062507 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Greene,M.W., and R.M. Kocan Toxicological Mechanisms of a Multicomponent
Agricultural Seed Protectant in the Rainbow
Trout (Oncorhynchus mykiss) and Fathead
Minnow (Pimephales promelas)
Can. J. Fish. Aquat. Sci.54:1387-1390 1997 2019/02/13
魚類 Pimephales promelas (Fathead minnow) Mortality (Survival) NOEC 210 days 0.0011 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
魚類 Poecilia reticulata (Guppy) Xenopus laevis Mortality LC50 1 days 0.025 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., D. Marchal-Segault, and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, on Several Animals Species of Freshwater
(Toxicite Aigue d'un Fongicide
Dithiocarbamate, le Thirame, vis-a-vis de
Plusieurs Especes Animales
d'eau Douce)
Environ. Pollut. A.31(3): 177-189 1983 2019/02/13
魚類 Poecilia reticulata (Guppy) Tubifex tubifex Mortality LC50 2 days 0.67 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Voronkin,A.S., and Y.T. Loshakov Toxic Effect of Pesticides on Tubifex tubifex Exp. Water Toxicol. (Eksp. Vodn. Toksikol. )5:169-
178
1973 2019/02/13
魚類 Danio rerio (Zebrafish) Development (Deformation) EC50 5 days 0.01202 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Boxtel,A.L., B. Pieterse, P. Cenijn, J.H.
Kamstra, A. Brouwer, W. Van Wieringen, J. De
Boer, and J. Legler
Dithiocarbamates Induce Craniofacial
Abnormalities and Downregulate sox9a During
Zebrafish Development
Toxicol. Sci.117(1): 209-217 2010 2019/02/13
魚類 Poecilia reticulata (Guppy) Xenopus laevis Mortality LC50 2 days 0.014 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., D. Marchal-Segault, and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, on Several Animals Species of Freshwater
(Toxicite Aigue d'un Fongicide
Dithiocarbamate, le Thirame, vis-a-vis de
Plusieurs Especes Animales
d'eau Douce)
Environ. Pollut. A.31(3): 177-189 1983 2019/02/13
魚類 others Rasbora heteromorpha Mortality LC10 2 days 0.0065 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Tooby,T.E., P.A. Hursey, and J.S. Alabaster The Acute Toxicity of 102 Pesticides and
Miscellaneous Substances to Fish
Chem. Ind. (Lond.)21:523-526 1975 2019/02/13
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 4 days 0.13 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
魚類 Danio rerio (Zebrafish) Development (Deformation) LOEL 0.83 days 0.004 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Tilton,F., J.K. La Du, M. Vue, N. Alzarban, and R.
L. Tanguay
Dithiocarbamates have a Common Toxic Effect on
Zebrafish Body Axis Formation
Toxicol. Appl. Pharmacol.216(1): 55-68 2006 2019/02/13
魚類 others Tilapia rendalli Genetics (Micronuclei) NOEL 4 days 2.5 mg/kg bdwt, Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Grisolia,C.K. A Comparison Between Mouse and Fish Micronucleus
Test Using Cyclophosphamide, Mitomycin C and
Various Pesticides
Mutat. Res.518(2): 145-150 2002 2019/02/13
魚類 Poecilia reticulata (Guppy) Lemna gibba Population (Abundance) EC50 7 days 1.6 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
魚類 others Tilapia rendalli Genetics (Micronuclei) LOEL 4 days 5 mg/kg bdwt, Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Grisolia,C.K. A Comparison Between Mouse and Fish Micronucleus
Test Using Cyclophosphamide, Mitomycin C and
Various Pesticides
Mutat. Res.518(2): 145-150 2002 2019/02/13
魚類 Poecilia reticulata (Guppy) Dugesia gonocephala Mortality LC50 2 days 0.26 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., D. Marchal-Segault, and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, on Several Animals Species of Freshwater
(Toxicite Aigue d'un Fongicide
Dithiocarbamate, le Thirame, vis-a-vis de
Plusieurs Especes Animales
d'eau Douce)
Environ. Pollut. A.31(3): 177-189 1983 2019/02/13
魚類 Poecilia reticulata (Guppy) Spirostomum ambiguum Morphology (Abnormal) EC50 1 days 0.006 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Nalecz-Jawecki,G., E. Kucharczyk, and J. Sawicki The Sensitivity of Protozoan Spirostomum ambiguum
to Selected Pesticides
Fresenius Environ. Bull.11(2): 98-101 2002 2019/02/13
魚類 Poecilia reticulata (Guppy) Xenopus laevis Mortality LC50 1 days 0.017 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., D. Marchal-Segault, and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, on Several Animals Species of Freshwater
(Toxicite Aigue d'un Fongicide
Dithiocarbamate, le Thirame, vis-a-vis de
Plusieurs Especes Animales
d'eau Douce)
Environ. Pollut. A.31(3): 177-189 1983 2019/02/13
魚類 Poecilia reticulata (Guppy) Paramecium caudatum Population (Abundance) IC50 2 days 0.324559 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Miyoshi,N., T. Kawano, M. Tanaka, T. Kadono, T.
Kosaka, M. Kunimoto, T. Takahashi, and H. Hosoya
Use of Paramecium Species in Bioassays for
Environmental Risk Management: Determination of
IC50 Values for Water Pollutants
J. Health Sci.49(6): 429-435 2003 2019/02/13
魚類 Poecilia reticulata (Guppy) Cloeon dipterum Mortality LC50 1 days 1.92 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, in Larvae of the Mayfly, Cloeon dipterum
- Effects of Various Parameters
Hydrobiologia101(3): 215-221 1983 2019/02/13
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 4 days 0.048 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kikuchi,M., T. Miyagaki, and M. Wakabayashi Evaluation of Pesticides Used in Golf Links by
Acute Toxicity Test on Rainbow Trout
Nippon Suisan Gakkaishi62(3): 414-419 1996 2019/02/13
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LOEC 60 days 0.001 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3): 129-145 1986 2019/02/13
魚類 Poecilia reticulata (Guppy) Cloeon dipterum Mortality LC50 1 days 1.03 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, in Larvae of the Mayfly, Cloeon dipterum
- Effects of Various Parameters
Hydrobiologia101(3): 215-221 1983 2019/02/13
魚類 Poecilia reticulata (Guppy) Xenopus laevis Mortality LC50 4 days 0.021 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., D. Marchal-Segault, and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, on Several Animals Species of Freshwater
(Toxicite Aigue d'un Fongicide
Dithiocarbamate, le Thirame, vis-a-vis de
Plusieurs Especes Animales
d'eau Douce)
Environ. Pollut. A.31(3): 177-189 1983 2019/02/13
魚類 Oncorhynchus mykiss (Rainbow trout) Growth (Growth, general) LOEC 60 days 0.00056 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3): 129-145 1986 2019/02/13
魚類 Poecilia reticulata (Guppy) Dugesia gonocephala Mortality LC50 4 days 0.048 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., D. Marchal-Segault, and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, on Several Animals Species of Freshwater
(Toxicite Aigue d'un Fongicide
Dithiocarbamate, le Thirame, vis-a-vis de
Plusieurs Especes Animales
d'eau Douce)
Environ. Pollut. A.31(3): 177-189 1983 2019/02/13
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 4 days 0.064911 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Greene,M.W., and R.M. Kocan Toxicological Mechanisms of a Multicomponent
Agricultural Seed Protectant in the Rainbow
Trout (Oncorhynchus mykiss) and Fathead
Minnow (Pimephales promelas)
Can. J. Fish. Aquat. Sci.54:1387-1390 1997 2019/02/13
魚類 others Ictalurus punctatus Mortality LC50 4 days 0.79 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Clemens,H.P., and K.E. Sneed Lethal Doses of Several Commercial Chemicals for
Fingerling Channel Catfish
U.S.Fish.Wildl.Serv., Spec.Sci.Rep.- Fish No.316,
Washington, DC:10 p.
1959 2019/02/13
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 4 days 0.28 mg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
魚類 others Ictalurus punctatus Mortality LC50 0.08 days >1 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Clemens,H.P., and K.E. Sneed Lethal Doses of Several Commercial Chemicals for
Fingerling Channel Catfish
U.S.Fish.Wildl.Serv., Spec.Sci.Rep.- Fish No.316,
Washington, DC:10 p.
1959 2019/02/13
魚類 Poecilia reticulata (Guppy) Paramecium trichium Population (Abundance) IC50 5 days 0.264456 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Miyoshi,N., T. Kawano, M. Tanaka, T. Kadono, T.
Kosaka, M. Kunimoto, T. Takahashi, and H. Hosoya
Use of Paramecium Species in Bioassays for
Environmental Risk Management: Determination of
IC50 Values for Water Pollutants
J. Health Sci.49(6): 429-435 2003 2019/02/13
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 1 days 0.3 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., J.L. Maas-Diepeveen, and H.C.M.
Overbeek
Sublethal Effects of Tetramethylthiuram Disulfide
(Thiram) in Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(1): 13-19 1986 2019/02/13
魚類 Poecilia reticulata (Guppy) Cloeon dipterum Mortality LC50 4 days 0.39 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, in Larvae of the Mayfly, Cloeon dipterum
- Effects of Various Parameters
Hydrobiologia101(3): 215-221 1983 2019/02/13
魚類 Danio rerio (Zebrafish) Multiple (Multiple effects reported as
one result)
EC50 5 days <0.000336 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Padilla,S., D. Corum, B. Padnos, D.L. Hunter, A.
Beam, K.A. Houck, N. Sipes, N. Kleinstreuer, T.
Knudsen, D.J. Dix, and
Zebrafish Developmental Screening of the ToxCast
Phase I Chemical Library
Reprod. Toxicol.33(2): 174-187 2012 2019/02/13
魚類 Danio rerio (Zebrafish) Mortality NR-LETH 0.83 days mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Raftery,T.D., G.M. Isales, K.L. Yozzo, and D.C.
Volz
High-Content Screening Assay for Identification
of Chemicals Impacting Spontaneous Activity in
Zebrafish Embryos
Environ. Sci. Technol.48(1): 804-810 2014 2025/05/07
魚類 Oncorhynchus mykiss (Rainbow trout) Multiple (Multiple effects reported as
one result)
LOEC 60 days <=0.00032 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3): 129-145 1986 2019/02/13
魚類 Poecilia reticulata (Guppy) Cloeon dipterum Mortality LC50 3 days 1.08 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, in Larvae of the Mayfly, Cloeon dipterum
- Effects of Various Parameters
Hydrobiologia101(3): 215-221 1983 2019/02/13
魚類 Poecilia reticulata (Guppy) Spirostomum teres Mortality LC50 1 days 0.433 mg/L Total 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Twagilimana,L., J. Bohatier, CA Groliere, F.
Bonnemoy, and D. Sargos
A New Low-Cost Microbiotest with the Protozoan
Spirostomum teres: Culture Conditions and
Assessment of Sensitivity of the Ciliate to
14 Pure Chemicals
Ecotoxicol. Environ. Saf.41(3): 231-244 1998 2019/02/13
魚類 Danio rerio (Zebrafish) Mortality LC50 0.83 days 3.365805 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Raftery,T.D., G.M. Isales, K.L. Yozzo, and D.C.
Volz
High-Content Screening Assay for Identification
of Chemicals Impacting Spontaneous Activity in
Zebrafish Embryos
Environ. Sci. Technol.48(1): 804-810 2014 2019/02/13
魚類 Oncorhynchus mykiss (Rainbow trout) Growth (Growth, general) LOEC 60 days <=0.00032 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3): 129-145 1986 2019/02/13
魚類 others Rasbora heteromorpha Mortality LC10 1 days 0.008 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Tooby,T.E., P.A. Hursey, and J.S. Alabaster The Acute Toxicity of 102 Pesticides and
Miscellaneous Substances to Fish
Chem. Ind. (Lond.)21:523-526 1975 2019/02/13
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality NOEL 4 days 0.09 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
魚類 others Ictalurus punctatus Mortality LC50 3 days 0.79 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Clemens,H.P., and K.E. Sneed Lethal Doses of Several Commercial Chemicals for
Fingerling Channel Catfish
U.S.Fish.Wildl.Serv., Spec.Sci.Rep.- Fish No.316,
Washington, DC:10 p.
1959 2019/02/13
魚類 Poecilia reticulata (Guppy) Xenopus laevis Mortality LC50 2 days 0.022 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., D. Marchal-Segault, and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, on Several Animals Species of Freshwater
(Toxicite Aigue d'un Fongicide
Dithiocarbamate, le Thirame, vis-a-vis de
Plusieurs Especes Animales
d'eau Douce)
Environ. Pollut. A.31(3): 177-189 1983 2019/02/13
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 4 days 0.28 mg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
魚類 Poecilia reticulata (Guppy) Intoxication (Immobile) NOEL 2 days <0.0013 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
魚類 others Rasbora heteromorpha Mortality LC50 1 days 0.02 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Tooby,T.E., P.A. Hursey, and J.S. Alabaster The Acute Toxicity of 102 Pesticides and
Miscellaneous Substances to Fish
Chem. Ind. (Lond.)21:523-526 1975 2019/02/13
魚類 Oncorhynchus mykiss (Rainbow trout) Multiple (Multiple effects reported as
one result)
EC50 60 days 0.00064 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3): 129-145 1986 2019/02/13
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 0.013198 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Greene,M.W., and R.M. Kocan Toxicological Mechanisms of a Multicomponent
Agricultural Seed Protectant in the Rainbow
Trout (Oncorhynchus mykiss) and Fathead
Minnow (Pimephales promelas)
Can. J. Fish. Aquat. Sci.54:1387-1390 1997 2019/02/13
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 0.035581 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Greene,M.W., and R.M. Kocan Toxicological Mechanisms of a Multicomponent
Agricultural Seed Protectant in the Rainbow
Trout (Oncorhynchus mykiss) and Fathead
Minnow (Pimephales promelas)
Can. J. Fish. Aquat. Sci.54:1387-1390 1997 2019/02/13
魚類 others Ictalurus punctatus Mortality LC50 1 days >1 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Clemens,H.P., and K.E. Sneed Lethal Doses of Several Commercial Chemicals for
Fingerling Channel Catfish
U.S.Fish.Wildl.Serv., Spec.Sci.Rep.- Fish No.316,
Washington, DC:10 p.
1959 2019/02/13
魚類 Poecilia reticulata (Guppy) Dugesia gonocephala Mortality LC50 3 days 0.088 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., D. Marchal-Segault, and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, on Several Animals Species of Freshwater
(Toxicite Aigue d'un Fongicide
Dithiocarbamate, le Thirame, vis-a-vis de
Plusieurs Especes Animales
d'eau Douce)
Environ. Pollut. A.31(3): 177-189 1983 2019/02/13
魚類 Poecilia reticulata (Guppy) Paramecium caudatum Population (Abundance) IC50 5 days 0.589016 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Miyoshi,N., T. Kawano, M. Tanaka, T. Kadono, T.
Kosaka, M. Kunimoto, T. Takahashi, and H. Hosoya
Use of Paramecium Species in Bioassays for
Environmental Risk Management: Determination of
IC50 Values for Water Pollutants
J. Health Sci.49(6): 429-435 2003 2019/02/13
魚類 Poecilia reticulata (Guppy) Cloeon dipterum Mortality LC50 2 days 1.3 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, in Larvae of the Mayfly, Cloeon dipterum
- Effects of Various Parameters
Hydrobiologia101(3): 215-221 1983 2019/02/13
魚類 Poecilia reticulata (Guppy) Cloeon dipterum Mortality LC50 4 days 1.01 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, in Larvae of the Mayfly, Cloeon dipterum
- Effects of Various Parameters
Hydrobiologia101(3): 215-221 1983 2019/02/13
魚類 Poecilia reticulata (Guppy) Paramecium trichium Population (Abundance) IC50 2 days 0.048082 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Miyoshi,N., T. Kawano, M. Tanaka, T. Kadono, T.
Kosaka, M. Kunimoto, T. Takahashi, and H. Hosoya
Use of Paramecium Species in Bioassays for
Environmental Risk Management: Determination of
IC50 Values for Water Pollutants
J. Health Sci.49(6): 429-435 2003 2019/02/13
魚類 Danio rerio (Zebrafish) Mortality NR-LETH 1 days 1 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Jouany,J.M., R. Truhaut, P. Vasseur, D. Klein, J.
F. Ferard, and P. Deschamps
An Example of Interaction between Environmental
Pollutants: Modification of Thiram Toxicity to
Freshwater Organisms by Nitrites or Nitrates
in Relation to Nitrosamine Synthesis
Ecotoxicol. Environ. Saf.9(3): 327-338 1985 2025/05/02
魚類 Pimephales promelas (Fathead minnow) Reproduction (Progeny counts/numbers) NOEC 210 days 0.0011 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
魚類 Poecilia reticulata (Guppy) Spirostomum ambiguum Mortality LC50 1 days 0.015 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Nalecz-Jawecki,G., E. Kucharczyk, and J. Sawicki The Sensitivity of Protozoan Spirostomum ambiguum
to Selected Pesticides
Fresenius Environ. Bull.11(2): 98-101 2002 2019/02/13
魚類 Poecilia reticulata (Guppy) Xenopus laevis Mortality LC50 4 days 0.013 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., D. Marchal-Segault, and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, on Several Animals Species of Freshwater
(Toxicite Aigue d'un Fongicide
Dithiocarbamate, le Thirame, vis-a-vis de
Plusieurs Especes Animales
d'eau Douce)
Environ. Pollut. A.31(3): 177-189 1983 2019/02/13
魚類 Poecilia reticulata (Guppy) Mortality LC50 4 days 0.27 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., J.L. Maas-Diepeveen, G. Niebeek,
W.H.A. Vergouw, P.S. Griffioen, and M.W.
Luijken
Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. I. Short-Term Toxicity
Tests
Aquat. Toxicol.7(3): 145-164 1985 2019/02/13
魚類 Danio rerio (Zebrafish) Multiple (Multiple effects reported as
one result)
LOEC 7 days 0.001 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., E.M.M. Grootelaar, and G.
Niebeek
Fish Embryos as Teratogenicity Screens: A
Comparison of Embryotoxicity Between Fish and
Birds
Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2019/02/13
魚類 Lepomis macrochirus (Bluegill) Mortality NOEL 4 days 0.1 mg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 4 days 0.042 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
魚類 Danio rerio (Zebrafish) Mortality LOEC 7 days 0.001 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., E.M.M. Grootelaar, and G.
Niebeek
Fish Embryos as Teratogenicity Screens: A
Comparison of Embryotoxicity Between Fish and
Birds
Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2019/02/13
魚類 Danio rerio (Zebrafish) Development (Deformation) NOEL 0.83 days <0.004 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Tilton,F., J.K. La Du, M. Vue, N. Alzarban, and R.
L. Tanguay
Dithiocarbamates have a Common Toxic Effect on
Zebrafish Body Axis Formation
Toxicol. Appl. Pharmacol.216(1): 55-68 2006 2019/02/13
魚類 others Rasbora heteromorpha Mortality LC50 2 days 0.012 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Tooby,T.E., P.A. Hursey, and J.S. Alabaster The Acute Toxicity of 102 Pesticides and
Miscellaneous Substances to Fish
Chem. Ind. (Lond.)21:523-526 1975 2019/02/13
魚類 others Ictalurus punctatus Mortality LC50 2 days >0.63 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Clemens,H.P., and K.E. Sneed Lethal Doses of Several Commercial Chemicals for
Fingerling Channel Catfish
U.S.Fish.Wildl.Serv., Spec.Sci.Rep.- Fish No.316,
Washington, DC:10 p.
1959 2019/02/13
魚類 Poecilia reticulata (Guppy) Xenopus laevis Mortality LC50 3 days 0.013 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., D. Marchal-Segault, and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, on Several Animals Species of Freshwater
(Toxicite Aigue d'un Fongicide
Dithiocarbamate, le Thirame, vis-a-vis de
Plusieurs Especes Animales
d'eau Douce)
Environ. Pollut. A.31(3): 177-189 1983 2019/02/13
魚類 Poecilia reticulata (Guppy) Xenopus laevis Mortality LC50 3 days 0.021 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., D. Marchal-Segault, and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, on Several Animals Species of Freshwater
(Toxicite Aigue d'un Fongicide
Dithiocarbamate, le Thirame, vis-a-vis de
Plusieurs Especes Animales
d'eau Douce)
Environ. Pollut. A.31(3): 177-189 1983 2019/02/13
魚類 Danio rerio (Zebrafish) Mortality LC50 7 days 0.034 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., E.M.M. Grootelaar, and G.
Niebeek
Fish Embryos as Teratogenicity Screens: A
Comparison of Embryotoxicity Between Fish and
Birds
Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2019/02/13
魚類 Poecilia reticulata (Guppy) Lemna gibba Population (Abundance) EC50 7 days 1.6 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
魚類 Pimephales promelas (Fathead minnow) Mortality (Survival) LOEC 210 days 0.0022 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
魚類 Poecilia reticulata (Guppy) Tetrahymena
pyriformis
Population (Population growth rate) IC50 0.37 days 0.125 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bogaerts,P., J. Bohatier, and F. Bonnemoy Use of the Ciliated Protozoan Tetrahymena
pyriformis for the Assessment of Toxicity and
Quantitative Structure-Activity
Relationships of Xenobiotics:
Comparison with the
Microtox Test
Ecotoxicol. Environ. Saf.49(3): 293-301 2001 2019/02/13
魚類 others Rasbora heteromorpha Mortality LC50 4 days 0.007 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Tooby,T.E., P.A. Hursey, and J.S. Alabaster The Acute Toxicity of 102 Pesticides and
Miscellaneous Substances to Fish
Chem. Ind. (Lond.)21:523-526 1975 2019/02/13
魚類 Poecilia reticulata (Guppy) Cloeon dipterum Mortality LC50 2 days 0.8 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, in Larvae of the Mayfly, Cloeon dipterum
- Effects of Various Parameters
Hydrobiologia101(3): 215-221 1983 2019/02/13
魚類 others Ictalurus punctatus Mortality LC50 0.04 days >1 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Clemens,H.P., and K.E. Sneed Lethal Doses of Several Commercial Chemicals for
Fingerling Channel Catfish
U.S.Fish.Wildl.Serv., Spec.Sci.Rep.- Fish No.316,
Washington, DC:10 p.
1959 2019/02/13
魚類 others Ictalurus punctatus Mortality LC50 0.16 days >1 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Clemens,H.P., and K.E. Sneed Lethal Doses of Several Commercial Chemicals for
Fingerling Channel Catfish
U.S.Fish.Wildl.Serv., Spec.Sci.Rep.- Fish No.316,
Washington, DC:10 p.
1959 2019/02/13
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 1 days 0.26 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., J.L. Maas-Diepeveen, and H.C.M.
Overbeek
Sublethal Effects of Tetramethylthiuram Disulfide
(Thiram) in Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(1): 13-19 1986 2019/02/13
魚類 Danio rerio (Zebrafish) Growth (Area) NOEC 0.83 days 0.021637 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Raftery,T.D., G.M. Isales, K.L. Yozzo, and D.C.
Volz
High-Content Screening Assay for Identification
of Chemicals Impacting Spontaneous Activity in
Zebrafish Embryos
Environ. Sci. Technol.48(1): 804-810 2014 2019/02/13
魚類 Poecilia reticulata (Guppy) Cloeon dipterum Mortality LC50 3 days 0.56 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, in Larvae of the Mayfly, Cloeon dipterum
- Effects of Various Parameters
Hydrobiologia101(3): 215-221 1983 2019/02/13
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 48 hours 0.190968 mol/L 17 Aquatic OASIS (OECD QSAR Toolbox) Unnamed Biodegradation and Bioaccumulation Data of
Existing Chemicals Based on the CSCL Japan
Chemicals Investigation and Testing Institute.
1992. Biodegradation and Bioaccumulation Data of
Existing Chemicals Based on the CSCL Japan,
ISBN 4-98074-101-1. Japan Chemical Industry
Ecology-Toxicology&Information Center;
1992 2019/02/22
魚類 Poecilia reticulata (Guppy) Dugesia gonocephala Mortality LC50 1 days 0.53 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Seuge,J., D. Marchal-Segault, and R. Bluzat Acute Toxicity of a Dithiocarbamate Fungicide,
Thiram, on Several Animals Species of Freshwater
(Toxicite Aigue d'un Fongicide
Dithiocarbamate, le Thirame, vis-a-vis de
Plusieurs Especes Animales
d'eau Douce)
Environ. Pollut. A.31(3): 177-189 1983 2019/02/13
魚類 Poecilia reticulata (Guppy) Lemna gibba Population (Abundance) NOEL 7 days <0.057 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
魚類 Poecilia reticulata (Guppy) Lemna gibba Population (Abundance) NOEL 7 days <0.057 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
魚類 Poecilia reticulata (Guppy) Tetrahymena
pyriformis
Enzyme(s) (Non-specific esterases) IC50 0.04 days 0.025 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bogaerts,P., J. Bohatier, and F. Bonnemoy Use of the Ciliated Protozoan Tetrahymena
pyriformis for the Assessment of Toxicity and
Quantitative Structure-Activity
Relationships of Xenobiotics:
Comparison with the
Microtox Test
Ecotoxicol. Environ. Saf.49(3): 293-301 2001 2019/02/13
魚類 Pimephales promelas (Fathead minnow) Reproduction (Progeny counts/numbers) LOEC 210 days 0.0022 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
魚類 Danio rerio (Zebrafish) Development (Teratogenic measurements) EC50 7 days 0.006 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., E.M.M. Grootelaar, and G.
Niebeek
Fish Embryos as Teratogenicity Screens: A
Comparison of Embryotoxicity Between Fish and
Birds
Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2019/02/13
魚類 Danio rerio (Zebrafish) Behavior (Activity, general) NOEC 0.83 days mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Raftery,T.D., G.M. Isales, K.L. Yozzo, and D.C.
Volz
High-Content Screening Assay for Identification
of Chemicals Impacting Spontaneous Activity in
Zebrafish Embryos
Environ. Sci. Technol.48(1): 804-810 2014 2019/02/13
魚類 others Ictalurus punctatus Mortality LC50 0.33 days >1 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Clemens,H.P., and K.E. Sneed Lethal Doses of Several Commercial Chemicals for
Fingerling Channel Catfish
U.S.Fish.Wildl.Serv., Spec.Sci.Rep.- Fish No.316,
Washington, DC:10 p.
1959 2019/02/13
魚類 Poecilia reticulata (Guppy) Intoxication (Immobile) EC50 2 days 0.0047 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 2 days 0.4 mg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2019/02/13
魚類 Poecilia reticulata (Guppy) Brachionus
plicatilis
Mortality LC50 1 days 0.05 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kyriakopoulou,K., P. Anastasiadou, and K. Machera Comparative Toxicities of Fungicide and Herbicide
Formulations on Freshwater and Marine Species
Bull. Environ. Contam. Toxicol.82(3): 290-295 2009 2019/02/13
魚類 Cyprinus carpio (Carp) Behavior 2.88 days 93 mg/kg bdwt 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Loeb,H.A., and W.H. Kelly Acute Oral Toxicity of 1,496 Chemicals Force-Fed
to Carp
U.S.Fish.Wildl.Serv., Sp.Sci.Rep.-Fish.No.471,
Washington, D.C.:124 p.
1963 2016/03/25
魚類 Cyprinus carpio (Carp) Mortality 1 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Jouany,J.M., R. Truhaut, P. Vasseur, D. Klein, J.
F. Ferard, and P. Deschamps
An Example of Interaction between Environmental
Pollutants: Modification of Thiram Toxicity to
Freshwater Organisms by Nitrites or Nitrates
in Relation to Nitrosamine Synthesis
Ecotoxicol. Environ. Saf.9(3): 327-338 1985 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 4 days 0.26 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Greene,M.W., and R.M. Kocan Toxicological Mechanisms of a Multicomponent
Agricultural Seed Protectant in the Rainbow
Trout (Oncorhynchus mykiss) and Fathead
Minnow (Pimephales promelas)
Can. J. Fish. Aquat. Sci.54:1387-1390 1997 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 148 nM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Greene,M.W., and R.M. Kocan Toxicological Mechanisms of a Multicomponent
Agricultural Seed Protectant in the Rainbow
Trout (Oncorhynchus mykiss) and Fathead
Minnow (Pimephales promelas)
Can. J. Fish. Aquat. Sci.54:1387-1390 1997 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 54.9 nM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Greene,M.W., and R.M. Kocan Toxicological Mechanisms of a Multicomponent
Agricultural Seed Protectant in the Rainbow
Trout (Oncorhynchus mykiss) and Fathead
Minnow (Pimephales promelas)
Can. J. Fish. Aquat. Sci.54:1387-1390 1997 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 20 hours 40~400 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Tilton,F., J.K. La Du, M. Vue, N. Alzarban, and R.
L. Tanguay
Dithiocarbamates have a Common Toxic Effect on
Zebrafish Body Axis Formation
Toxicol. Appl. Pharmacol.216(1): 55-68 2006 2016/03/25
魚類 Cyprinus carpio (Carp) Mortality 2.88 days 121 mg/kg bdwt 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Loeb,H.A., and W.H. Kelly Acute Oral Toxicity of 1,496 Chemicals Force-Fed
to Carp
U.S.Fish.Wildl.Serv., Sp.Sci.Rep.-Fish.No.471,
Washington, D.C.:124 p.
1963 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 2 days 400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LOEC 60 days 1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3): 129-145 1986 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LOEC 210 days 2.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality NOEL 4 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 4 days 130 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality 1 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Jouany,J.M., R. Truhaut, P. Vasseur, D. Klein, J.
F. Ferard, and P. Deschamps
An Example of Interaction between Environmental
Pollutants: Modification of Thiram Toxicity to
Freshwater Organisms by Nitrites or Nitrates
in Relation to Nitrosamine Synthesis
Ecotoxicol. Environ. Saf.9(3): 327-338 1985 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Growth LOEC 60 days <=0.32 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3): 129-145 1986 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) No Group Code LOEC 60 days <=0.32 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3): 129-145 1986 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Growth LOEC 60 days 0.56 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3): 129-145 1986 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 7 days 34 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., E.M.M. Grootelaar, and G.
Niebeek
Fish Embryos as Teratogenicity Screens: A
Comparison of Embryotoxicity Between Fish and
Birds
Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 60 days 1.1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3): 129-145 1986 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality NOEC 210 days 1.1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 4 days 0.27 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Greene,M.W., and R.M. Kocan Toxicological Mechanisms of a Multicomponent
Agricultural Seed Protectant in the Rainbow
Trout (Oncorhynchus mykiss) and Fathead
Minnow (Pimephales promelas)
Can. J. Fish. Aquat. Sci.54:1387-1390 1997 2016/03/25
魚類 Danio rerio (Zebrafish) Growth LOEL 20 hours 4 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Tilton,F., J.K. La Du, M. Vue, N. Alzarban, and R.
L. Tanguay
Dithiocarbamates have a Common Toxic Effect on
Zebrafish Body Axis Formation
Toxicol. Appl. Pharmacol.216(1): 55-68 2006 2016/03/25
魚類 Danio rerio (Zebrafish) No Group Code 5 days 80 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Padilla,S., D. Corum, B. Padnos, D.L. Hunter, A.
Beam, K.A. Houck, N. Sipes, N. Kleinstreuer, T.
Knudsen, D.J. Dix, and
Zebrafish Developmental Screening of the ToxCast
Phase I Chemical Library
Reprod. Toxicol.33(2): 174-187 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality NR-LETH 1 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Jouany,J.M., R. Truhaut, P. Vasseur, D. Klein, J.
F. Ferard, and P. Deschamps
An Example of Interaction between Environmental
Pollutants: Modification of Thiram Toxicity to
Freshwater Organisms by Nitrites or Nitrates
in Relation to Nitrosamine Synthesis
Ecotoxicol. Environ. Saf.9(3): 327-338 1985 2025/05/07
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 4 days 48 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kikuchi,M., T. Miyagaki, and M. Wakabayashi Evaluation of Pesticides Used in Golf Links by
Acute Toxicity Test on Rainbow Trout
Nippon Suisan Gakkaishi62(3): 414-419 1996 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 210 days 1.1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction LOEC 210 days 2.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 1 days 260 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., J.L. Maas-Diepeveen, and H.C.M.
Overbeek
Sublethal Effects of Tetramethylthiuram Disulfide
(Thiram) in Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(1): 13-19 1986 2016/03/25
魚類 Danio rerio (Zebrafish) No Group Code LOEC 7 days 1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., E.M.M. Grootelaar, and G.
Niebeek
Fish Embryos as Teratogenicity Screens: A
Comparison of Embryotoxicity Between Fish and
Birds
Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2016/03/25
魚類 Danio rerio (Zebrafish) No Group Code EC50 5 days <0.0014 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Padilla,S., D. Corum, B. Padnos, D.L. Hunter, A.
Beam, K.A. Houck, N. Sipes, N. Kleinstreuer, T.
Knudsen, D.J. Dix, and
Zebrafish Developmental Screening of the ToxCast
Phase I Chemical Library
Reprod. Toxicol.33(2): 174-187 2012 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 4 days 42 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2016/03/25
魚類 Poecilia reticulata (Guppy) Mortality LC50 4 days 270 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., J.L. Maas-Diepeveen, G. Niebeek,
W.H.A. Vergouw, P.S. Griffioen, and M.W.
Luijken
Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. I. Short-Term Toxicity
Tests
Aquat. Toxicol.7(3): 145-164 1985 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 4 days 280 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEL 20 hours <4 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Tilton,F., J.K. La Du, M. Vue, N. Alzarban, and R.
L. Tanguay
Dithiocarbamates have a Common Toxic Effect on
Zebrafish Body Axis Formation
Toxicol. Appl. Pharmacol.216(1): 55-68 2006 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Physiology 1 days 180 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., J.L. Maas-Diepeveen, and H.C.M.
Overbeek
Sublethal Effects of Tetramethylthiuram Disulfide
(Thiram) in Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(1): 13-19 1986 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LOEC 7 days 1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., E.M.M. Grootelaar, and G.
Niebeek
Fish Embryos as Teratogenicity Screens: A
Comparison of Embryotoxicity Between Fish and
Birds
Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) No Group Code EC50 60 days 0.64 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(2/3): 129-145 1986 2016/03/25
魚類 Danio rerio (Zebrafish) Growth EC50 7 days 6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., E.M.M. Grootelaar, and G.
Niebeek
Fish Embryos as Teratogenicity Screens: A
Comparison of Embryotoxicity Between Fish and
Birds
Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 1 days 300 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., J.L. Maas-Diepeveen, and H.C.M.
Overbeek
Sublethal Effects of Tetramethylthiuram Disulfide
(Thiram) in Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(1): 13-19 1986 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Cellular Effects 21 days 5 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., T. Helder, and W. Seinen Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. IV. Teratogenicity and
Histopathology in Rainbow Trout (Salmo
gairdneri)
Aquat. Toxicol.9(2/3): 147-159 1986 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 4 days 280 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.:
1992 2016/03/25
魚類 Oncorhynchus mykiss Mortality LC50 171 µg/L 17 Aquatic OASIS (OECD QSAR Toolbox) EFSA doi:10.2903/j.efsa.2017.4700 http://dx.doi.org/10.2903/j.efsa.2017.4700 2017 2023/07/18
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality/Mortality LC50 96 hours 0.54 ppm Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.
1992
魚類 Cyprinodon variegatus (Sheepshead minnow) mortality NOEC 96 hours 0.09 mg/L meas. (arithm.mean) act.ingr. 12 ECHA Information on Registered Substances 1 study report 1992 2020/03/18
魚類 Lepomis macrochirus (Bluegill) Mortality/Mortality LC50 96 hours 280 ppb Not coded 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.
1992
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 0.27 mg/L × 12 ECHA Information on Registered Substances 2 study report 1983
魚類 Oryzias latipes Mortality LC50 48 hours 0.000000794 mol/L 17 Aquatic OASIS (OECD QSAR Toolbox) Teleostei Biodegradation and Bioaccumulation Data of
Existing Chemicals Based on the CSCL Japan
Chemicals Investigation and Testing Institute.
1992. Biodegradation and Bioaccumulation Data of
Existing Chemicals Based on the CSCL Japan,
ISBN 4-98074-101-1. Japan Chemical Industry
Ecology-Toxicology&Information Center;
1992 2023/07/18
魚類 Lepomis macrochirus (Bluegill) mortality NOEC 96 hours <0.056 × 12 ECHA Information on Registered Substances 2 study report 1983
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 48 hours 0.000794 mmol/L 17 Aquatic OASIS (OECD QSAR Toolbox) Biodegradation and Bioaccumulation Data of
Existing Chemicals Based on the CSCL Japan
Chemicals Investigation and Testing Institute.
1992. Biodegradation and Bioaccumulation Data of
Existing Chemicals Based on the CSCL Japan,
ISBN 4-98074-101-1. Japan Chemical Industry
Ecology-Toxicology&Information Center;
1992 2023/07/14
魚類 Pimephales promelas (Fathead minnow) mortality NOEC 96 hours 0.1 mg/L × 12 ECHA Information on Registered Substances 2 study report 1983
魚類 Cyprinodon variegatus (Sheepshead minnow) mortality LC50 96 hours 0.54 mg/L 12 ECHA Information on Registered Substances 1 study report 1992
魚類 Lepomis macrochirus (Bluegill) mortality LC50 96 hours 0.13 mg/L × 12 ECHA Information on Registered Substances 2 study report 1983
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality/Mortality LC50 96 hours 130 ppb Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.
1992
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality/Mortality NOEL 96 hours 0.09 ppm Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.
1992
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality/Mortality LC50 24 hours 300 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., J.L. Maas-Diepeveen, and H.C.M.
Overbeek
Sublethal Effects of Tetramethylthiuram Disulfide
(Thiram) in Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(1) 1986
魚類 Pimephales promelas (Fathead minnow) Mortality/Mortality LC50 96 hours 148 nM Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Greene,M.W., and R.M. Kocan Toxicological Mechanisms of a Multicomponent
Agricultural Seed Protectant in the Rainbow
Trout (Oncorhynchus mykiss) and Fathead
Minnow (Pimephales promelas)
Can. J. Fish. Aquat. Sci.54 1997
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality/Mortality LC50 96 hours 48 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kikuchi,M., T. Miyagaki, and M. Wakabayashi Evaluation of Pesticides Used in Golf Links by
Acute Toxicity Test on Rainbow Trout
Nippon Suisan Gakkaishi62(3) 1996
魚類 Oncorhynchus mykiss (Rainbow trout) mortality NOEC 96 hours 0.01 mg/L 12 ECHA Information on Registered Substances 1 study report 2000
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality/Mortality LC50 24 hours 260 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., J.L. Maas-Diepeveen, and H.C.M.
Overbeek
Sublethal Effects of Tetramethylthiuram Disulfide
(Thiram) in Rainbow Trout (Salmo gairdneri)
Aquat. Toxicol.9(1) 1986
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality/Mortality LC50 96 hours 0.26 μM Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Greene,M.W., and R.M. Kocan Toxicological Mechanisms of a Multicomponent
Agricultural Seed Protectant in the Rainbow
Trout (Oncorhynchus mykiss) and Fathead
Minnow (Pimephales promelas)
Can. J. Fish. Aquat. Sci.54 1997
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 96 hours 0.046 mg/L 12 ECHA Information on Registered Substances 1 study report 2000
魚類 Lepomis macrochirus (Bluegill) Mortality/Mortality LC50 96 hours 42 ppb Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.
1992
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality/Mortality LC50 96 hours 0.27 μM Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Greene,M.W., and R.M. Kocan Toxicological Mechanisms of a Multicomponent
Agricultural Seed Protectant in the Rainbow
Trout (Oncorhynchus mykiss) and Fathead
Minnow (Pimephales promelas)
Can. J. Fish. Aquat. Sci.54 1997
魚類 Lepomis macrochirus (Bluegill) Mortality/Mortality LC50 96 hours 0.28 ppm Not coded 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.
1992
魚類 Pimephales promelas (Fathead minnow) Mortality/Mortality LC50 96 hours 54.9 nM Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Greene,M.W., and R.M. Kocan Toxicological Mechanisms of a Multicomponent
Agricultural Seed Protectant in the Rainbow
Trout (Oncorhynchus mykiss) and Fathead
Minnow (Pimephales promelas)
Can. J. Fish. Aquat. Sci.54 1997
魚類 Poecilia reticulata (Guppy) Mortality/Mortality LC50 96 hours 270 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Van Leeuwen,C.J., J.L. Maas-Diepeveen, G. Niebeek,
W.H.A. Vergouw, P.S. Griffioen, and M.W.
Luijken
Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. I. Short-Term Toxicity
Tests
Aquat. Toxicol.7(3) 1985
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality/Mortality LC50 48 hours 400 ppb Not coded 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.
1992
魚類 Lepomis macrochirus (Bluegill) Mortality/Mortality NOEL 96 hours 0.1 ppm Not coded 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly:
Environmental Effects Database (EEDB))
Environmental Fate and Effects Division, U.S.EPA,
Washington, D.C.
1992
魚類 Oryzias latipes (Japanese medaka) mortality LOEC 96 hours 0.2 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute toxicity test of Bis (dimethylthiocarbamoyl)
disulfide (CAS No.:137-26-8) in fish (Oryzias
latipes)
2008 2018/12/05
魚類 Oryzias latipes (Japanese medaka) mortality LC50 96 hours 0.17 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute toxicity test of Bis (dimethylthiocarbamoyl)
disulfide (CAS No.:137-26-8) in fish (Oryzias
latipes)
2008 2018/12/05
魚類 Lepomis macrochirus (Bluegill) mortality LC50 96 hours <0.13 mg/L 12 ECHA Information on Registered Substances 2 study report 1983 2016/03/18
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours 46 μg/L 3 USEPA Pesticide Ecotoxicity Database N. Federoff 2012 2016/02/02
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours 380 μg/L 3 USEPA Pesticide Ecotoxicity Database R. Felthousen 1979 2016/02/02
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 0.27 mg/L 12 ECHA Information on Registered Substances 2 study report 1983 2016/03/18
魚類 Lepomis macrochirus (Bluegill) LC50 96 hours 280 μg/L 3 USEPA Pesticide Ecotoxicity Database McCann/Bascietto 1972 2016/02/02
魚類 Oncorhynchus mykiss (Rainbow trout) SURVIVE, GROWTH LC50 28 days 49.1 μg/L 3 USEPA Pesticide Ecotoxicity Database N. Federoff 2012 2016/02/02
魚類 Lepomis macrochirus (Bluegill) LC50 96 hours 560 μg/L 3 USEPA Pesticide Ecotoxicity Database R. Felthousen 1979 2016/02/02
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 96 hours 0.046 mg/L 12 ECHA Information on Registered Substances 1 study report 2000 2016/03/18
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 48 hours 400 μg/L 3 USEPA Pesticide Ecotoxicity Database J.McCann/Bascietto 1983 2016/02/02
魚類 Cyprinodon variegatus (Sheepshead minnow) LC50 96 hours 540 μg/L 3 USEPA Pesticide Ecotoxicity Database B. Montague 1993 2016/02/02
魚類 Lepomis macrochirus (Bluegill) LC50 96 hours 42 μg/L 3 USEPA Pesticide Ecotoxicity Database J.J. Bascietto 1983 2016/02/02
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 48 hours 0.191 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) - Biodegradation and Bioaccumulation Data of
Existing Chemicals Based on the CSCL Japan
1992 2016/02/08
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours 126 μg/L 3 USEPA Pesticide Ecotoxicity Database J.J. Bascietto 1983 2016/02/02
魚類 Cyprinodon variegatus (Sheepshead minnow) mortality LC50 96 hours 0.54 mg/L 12 ECHA Information on Registered Substances 1 study report 1992 2016/03/18
魚類 Poecilia reticulata (Guppy) LC50 96 hours 0.27 mg/L 4 OECD SIDS (HPVC) 3 Van Leeuwen CJ, Maas-Diepeveen JL, Niebeek G,
Vergouwm WHA, Griffioen PS and Luijken MW
Aquatic toxicological aspects of dithiocarbamates
and related compounds. I. Short-term toxicity
test
Aquatic toxicology 1985 2018/12/05
魚類 Oryzias latipes (Japanese medaka) mortality LC50 96 hours 0.17 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute toxicity test of Bis (dimethylthiocarbamoyl)
disulfide (CAS No.:137-26-8) in fish (Oryzias
latipes)
2008 2018/12/05
魚類 Oryzias latipes (Japanese medaka) mortality NOEC 96 hours 0.076 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute toxicity test of Bis (dimethylthiocarbamoyl)
disulfide (CAS No.:137-26-8) in fish (Oryzias
latipes)
2008 2018/12/05
魚類 Oryzias latipes (Japanese medaka) mortality NOEC 96 hours 0.076 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute toxicity test of Bis (dimethylthiocarbamoyl)
disulfide (CAS No.:137-26-8) in fish (Oryzias
latipes)
2008 2018/12/05
魚類 Poecilia reticulata (Guppy) LC50 96 hours 0.27 mg/L 4 OECD SIDS (HPVC) 3 Van Leeuwen CJ, Maas-Diepeveen JL, Niebeek G,
Vergouwm WHA, Griffioen PS and Luijken MW
Aquatic toxicological aspects of dithiocarbamates
and related compounds. I. Short-term toxicity
test
Aquatic toxicology 1985 2018/12/05
魚類 Oncorhynchus mykiss (Rainbow trout) breakdown products LC50 24 hours 0.26 mg/L 10 EHC (Environmental Health Criteria) VAN LEEUWEN, C.J. Ecotoxicological aspects of dithiocarbamates Utrecht, University of Utrecht (Thesis). 1986 2018/12/13
魚類 Oryzias latipes (Japanese medaka) mortality LOEC 96 hours 0.2 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute toxicity test of Bis (dimethylthiocarbamoyl)
disulfide (CAS No.:137-26-8) in fish (Oryzias
latipes)
2008 2018/12/05
魚類 Cyprinus carpio (Carp) LC50 96 hours 100 μg/L 2 日本環境省 農薬登録保留基準(水産動植物) 2018/12/18
魚類 Poecilia reticulata (Guppy) breakdown products LC50 96 hours 0.27 mg/L 10 EHC (Environmental Health Criteria) VAN LEEUWEN, C.J. Ecotoxicological aspects of dithiocarbamates Utrecht, University of Utrecht (Thesis). 1986 2018/12/13
魚類 Cyprinus carpio (Carp) LC50 4 mg/L 10 EHC (Environmental Health Criteria) WORTHING, C.R. & WALKER, S.B. The pesticide manual: a world compendium, 7th ed. Croydon, British Crop Protection Council. 2016/03/06
魚類 Oryzias latipes mortality (fish) NOEC 96 hours <125 μg/L nominal act. ingr. 12 ECHA Information on Registered Substances 1 study report 2015 2023/08/04
魚類 Poecilia reticulata mortality (fish) NOEC 96 hours 137 μg/L nominal act. ingr. 12 ECHA Information on Registered Substances 1 study report 2015 2023/08/04
魚類 Lepomis macrochirus (Bluegill) mortality LC50 96 hours 0.13 mg/L 12 ECHA Information on Registered Substances 2 study report Unnamed 1983 2019/02/20
魚類 Poecilia reticulata mortality (fish) LC50 96 hours 216 μg/L nominal act. ingr. 12 ECHA Information on Registered Substances 1 study report 2015 2023/08/04
魚類 Oncorhynchus mykiss mortality (fish) LC50 96 hours 171 μg/L nominal act. ingr. 12 ECHA Information on Registered Substances 1 study report 2015 2023/08/04
魚類 Oncorhynchus mykiss mortality (fish) NOEC 96 hours 113 μg/L nominal act. ingr. 12 ECHA Information on Registered Substances 1 study report 2015 2023/08/04
魚類 Poecilia reticulata abnormality appearance (fish) NOEC 96 hours <105 μg/L nominal act. ingr. 12 ECHA Information on Registered Substances 1 study report 2015 2023/08/04
魚類 Pimephales promelas mortality (fish) LC50 96 hours 188 μg/L nominal test mat. 12 ECHA Information on Registered Substances 1 study report 2015 2023/08/04
魚類 Oncorhynchus mykiss abnormality appearance (fish) NOEC 96 hours <54 μg/L nominal act. ingr. 12 ECHA Information on Registered Substances 1 study report 2015 2023/08/04
魚類 Oryzias latipes mortality (fish) LC50 96 hours 179 μg/L nominal act. ingr. 12 ECHA Information on Registered Substances 1 study report 2015 2023/08/04
魚類 Pimephales promelas mortality (fish) NOEC 96 hours 91 μg/L nominal test mat. 12 ECHA Information on Registered Substances 1 study report 2015 2023/08/04
魚類 Oncorhynchus mykiss mortality (fish) LC50 96 hours 89 μg/L nominal act. ingr. × 12 ECHA Information on Registered Substances 2 study report 2001 2023/08/04
魚類 Oncorhynchus mykiss mortality (fish) NOEC 96 hours 20 μg/L nominal act. ingr. × 12 ECHA Information on Registered Substances 2 study report 2001 2023/08/04
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours 46 ppb 3 USEPA Pesticide Ecotoxicity Database N. Federoff 2012 2018/03/07
魚類 Lepomis macrochirus (Bluegill) LC50 96 hours 560 ppb 3 USEPA Pesticide Ecotoxicity Database R. Felthousen 1979 2018/03/07
魚類 Lepomis macrochirus (Bluegill) LC50 96 hours 280 ppb 3 USEPA Pesticide Ecotoxicity Database McCann/Bascietto 1972 2018/03/07
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours 380 ppb 3 USEPA Pesticide Ecotoxicity Database R. Felthousen 1979 2018/03/07
魚類 Oryzias latipes (Japanese medaka) LC50 96 hours 0.17 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute toxicity test of Bis (dimethylthiocarbamoyl)
disulfide (CAS No.:137-26-8) in fish (Oryzias
latipes)
2008 2016/02/22
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 0.13 mg/L 10 EHC (Environmental Health Criteria) WORTHING, C.R. & WALKER, S.B. The pesticide manual: a world compendium, 7th ed. Croydon, British Crop Protection Council. 2016/03/06
魚類 Lepomis macrochirus (Bluegill) LC50 0.23 mg/L 10 EHC (Environmental Health Criteria) WORTHING, C.R. & WALKER, S.B. The pesticide manual: a world compendium, 7th ed. Croydon, British Crop Protection Council. 2016/03/06
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 24 hours 0.26 mg/L 10 EHC (Environmental Health Criteria) VAN LEEUWEN, C.J. Ecotoxicological aspects of dithiocarbamates Utrecht, University of Utrecht (Thesis) 2016/03/06
魚類 Poecilia reticulata (Guppy) LC50 96 hours 0.27 mg/L 10 EHC (Environmental Health Criteria) VAN LEEUWEN, C.J. Ecotoxicological aspects of dithiocarbamates Utrecht, University of Utrecht (Thesis) 2016/03/06
魚類 Cyprinus carpio (Carp) Mortality TL50 4 days 0.3 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
b Verma, S.R., I.P. Tonk, and R.C. Dalela Determination of the Maximum Acceptable Toxicant
Concentration (MATC) and the Safe Concentration
for Certain Aquatic Pollutants.
Acta Hydrochim.Hydrobiol. 1981 2016/03/07
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 13.2 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
b Greene, M.W., and R.M. Kocan Toxicological Mechanisms of a Multicomponent
Agricultural Seed Protectant in the Rainbow
Trout (Oncorhynchus mykiss) and Fathead
Minnow (Pimephales promelas).
Can.J.Fish.Aquat.Sci. 1997 2016/03/07
魚類 Cyprinus carpio (Carp) 死亡 LC50 96 hours 100 μg/L 2 日本環境省 農薬登録保留基準(水産動植物) 環境省 水産動植物の被害防止に係る農薬登録保留基準の設定に関する資料 2016/02/17
魚類 Poecilia reticulata (Guppy) LC50 96 hours 0.27 mg/L 4 OECD SIDS (HPVC) 3 Van Leeuwen CJ, Maas-Diepeveen JL, Niebeek G,
Vergouwm WHA, Griffioen PS and Luijken MW
Aquatic toxicological aspects of dithiocarbamates
and related compounds. I. Short-term toxicity
test
Aquatic toxicology 1985 2016/02/22
魚類 Oryzias latipes (Japanese medaka) LC50 48 hours 0.29 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute toxicity test of Bis (dimethylthiocarbamoyl)
disulfide (CAS No.:137-26-8) in fish (Oryzias
latipes)
2008 2016/02/22
魚類 Oryzias latipes (Japanese medaka) LC50 72 hours 0.23 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute toxicity test of Bis (dimethylthiocarbamoyl)
disulfide (CAS No.:137-26-8) in fish (Oryzias
latipes)
2008 2016/02/22
魚類 Pimephales promelas (Fathead minnow) other: mortality and growth LOEC 33 days 9.3 μg/L 12 ECHA Information on Registered Substances 1 study report 2008
魚類 Pimephales promelas Other NOEC 1.1 µg/L 17 Aquatic OASIS (OECD QSAR Toolbox) EFSA http://dx.doi.org/10.2903/j.efsa.2017.4700doi:10.
2903/j.efsa.2017.4700
2017 2023/07/18
魚類 Pimephales promelas (Fathead minnow) other: mortality and growth NOEC 33 days 4.6 μg/L 12 ECHA Information on Registered Substances 1 study report 2008
魚類 Pimephales promelas (Fathead minnow) number hatched NOEC 33 days 9.3 μg/L 12 ECHA Information on Registered Substances 1 study report 2008
魚類 Brachydanio rerio (Zebrafish) LC50 7 days 0.034 mg/L 4 OECD SIDS (HPVC) 4 Van Leeuwen CJ, Grootelaar EMM, and Niebeek G Fish Embryos as Teratogenicity Screens : A
Comparison of Embryotoxicity between Fish and
Birds
Ecotoxicology and Environmental Safety 1990 2018/12/05
魚類 Oncorhynchus mykiss (Rainbow trout) EC50 60 days 0.00064 mg/L 4 OECD SIDS (HPVC) 4 Van leeuwen CJ, Espeldoorn A and Mol F Aquatic toxicological aspects of dithiocarbamates
and related compounds. III. Embryolarval studies
with rainbow trout (Salmo Gairdneri)
Aquatic Toxicology 1986 2018/12/05
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 60 days 0.0011 mg/L 4 OECD SIDS (HPVC) 4 Van leeuwen CJ, Espeldoorn A and Mol F Aquatic toxicological aspects of dithiocarbamates
and related compounds. III. Embryolarval studies
with rainbow trout (Salmo Gairdneri)
Aquatic Toxicology 1986 2018/12/05
魚類 Cyprinodon variegatus (Sheepshead minnow) mortality NOEC 96 hours 0.09 mg/L 12 ECHA Information on Registered Substances 1 study report 1992 2025/05/07
魚類 Lepomis macrochirus (Bluegill) NOEL 96 hours 32 μg/L 3 USEPA Pesticide Ecotoxicity Database J.J. Bascietto 1983 2016/02/02
魚類 Oncorhynchus mykiss (Rainbow trout) NOEL 96 hours 11 μg/L 3 USEPA Pesticide Ecotoxicity Database N. Federoff 2012 2016/02/02
魚類 Lepomis macrochirus (Bluegill) NOEL 96 hours 100 μg/L 3 USEPA Pesticide Ecotoxicity Database McCann/Bascietto 1972 2016/02/02
魚類 Oncorhynchus mykiss (Rainbow trout) SURVIVE, GROWTH LOEC 28 days 25 μg/L 3 USEPA Pesticide Ecotoxicity Database N. Federoff 2012 2016/02/02
魚類 Oncorhynchus mykiss (Rainbow trout) SURVIVE, GROWTH NOEL 28 days 15 μg/L 3 USEPA Pesticide Ecotoxicity Database N. Federoff 2012 2016/02/02
魚類 Oncorhynchus mykiss (Rainbow trout) mortality NOEC 96 hours 0.01 mg/L 12 ECHA Information on Registered Substances 1 study report 2000 2025/05/07
魚類 Pimephales promelas (Fathead minnow) mortality NOEC 96 hours 0.1 mg/L 12 ECHA Information on Registered Substances 2 study report 1983 2025/05/07
魚類 Oncorhynchus mykiss (Rainbow trout) SURVIVE, GROWTH NOEL 28 days 25 μg/L 3 USEPA Pesticide Ecotoxicity Database N. Federoff 2012 2016/02/02
魚類 Pimephales promelas (Fathead minnow) mortality and growth LOEC 33 days 9.3 μg/L 12 ECHA Information on Registered Substances 1 study report 2008 2023/07/12
魚類 Pimephales promelas (Fathead minnow) EGGSLAID, SURVIVE LOEC 210 days 2.2 μg/L 3 USEPA Pesticide Ecotoxicity Database N. Federoff 2011 2016/02/02
魚類 Pimephales promelas (Fathead minnow) number hatched NOEC 33 days >9.3 μg/L 12 ECHA Information on Registered Substances 1 study report 2008 2023/07/12
魚類 Pimephales promelas (Fathead minnow) EGGSLAID, SURVIVE NOEL 210 days 1.1 μg/L 3 USEPA Pesticide Ecotoxicity Database N. Federoff 2011 2016/02/02
魚類 Pimephales promelas (Fathead minnow) mortality and growth NOEC 33 days 4.6 μg/L 12 ECHA Information on Registered Substances 1 study report 2008 2023/07/12
魚類 Oncorhynchus mykiss (Rainbow trout) NOEL 96 hours 56 μg/L 3 USEPA Pesticide Ecotoxicity Database J.J. Bascietto 1983 2016/02/02
魚類 Oncorhynchus mykiss (Rainbow trout) mortality NOEC 42 days 0.02 mg/L 12 ECHA Information on Registered Substances 1 study report 2001 2025/05/07
魚類 Lepomis macrochirus (Bluegill) mortality NOEC 96 hours <0.056 mg/L 12 ECHA Information on Registered Substances 2 study report 1983 2025/05/07
魚類 Oncorhynchus mykiss (Rainbow trout) NOEL 48 hours 32 μg/L 3 USEPA Pesticide Ecotoxicity Database J.McCann/Bascietto 1983 2016/02/02
魚類 Cyprinodon variegatus (Sheepshead minnow) NOEL 96 hours 90 μg/L 3 USEPA Pesticide Ecotoxicity Database B. Montague 1993 2016/02/02
魚類 Oncorhynchus mykiss (Rainbow trout) growth rate NOEC 42 days 0.012 mg/L 12 ECHA Information on Registered Substances 1 study report 2001 2025/05/07
魚類 Oncorhynchus mykiss (Rainbow trout) growth rate LOEC 28 days 0.02 mg/L 12 ECHA Information on Registered Substances 1 study report 2001 2025/05/07
魚類 Brachydanio rerio (Zebrafish) EC50 7 days 0.006 mg/L 4 OECD SIDS (HPVC) 4 Van Leeuwen CJ, Grootelaar EMM, and Niebeek G Fish Embryos as Teratogenicity Screens : A
Comparison of Embryotoxicity between Fish and
Birds
Ecotoxicology and Environmental Safety 1990 2018/12/05
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LOEC 60 days 0.001 mg/L 4 OECD SIDS (HPVC) 4 Van leeuwen CJ, Espeldoorn A and Mol F Aquatic toxicological aspects of dithiocarbamates
and related compounds. III. Embryolarval studies
with rainbow trout (Salmo Gairdneri)
Aquatic Toxicology 1986 2018/12/05
魚類 Brachydanio rerio (Zebrafish) mortality LOEC 7 days 0.001 mg/L 4 OECD SIDS (HPVC) 4 Van Leeuwen CJ, Grootelaar EMM, and Niebeek G Fish Embryos as Teratogenicity Screens : A
Comparison of Embryotoxicity between Fish and
Birds
Ecotoxicology and Environmental Safety 1990 2018/12/05
魚類 Oncorhynchus mykiss (Rainbow trout) SURVIVE, GROWTH NOEL 28 days 25 ppb 3 USEPA Pesticide Ecotoxicity Database N. Federoff 2012 2018/03/07
魚類 Oncorhynchus mykiss (Rainbow trout) SURVIVE, GROWTH LC50 28 days 49.1 ppb 3 USEPA Pesticide Ecotoxicity Database N. Federoff 2012 2018/03/07
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 60 days 0.0011 mg/L 4 OECD SIDS (HPVC) 4 Van leeuwen CJ, Espeldoorn A and Mol F Aquatic toxicological aspects of dithiocarbamates
and related compounds. III. Embryolarval studies
with rainbow trout (Salmo Gairdneri)
Aquatic Toxicology 1986 2018/12/05
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LOEC 60 days 0.001 mg/L 4 OECD SIDS (HPVC) 4 Van leeuwen CJ, Espeldoorn A and Mol F Aquatic toxicological aspects of dithiocarbamates
and related compounds. III. Embryolarval studies
with rainbow trout (Salmo Gairdneri)
Aquatic Toxicology 1986 2018/12/05
魚類 Brachydanio rerio (Zebrafish) LC50 7 days 0.034 mg/L 4 OECD SIDS (HPVC) 4 Van Leeuwen CJ, Grootelaar EMM, and Niebeek G Fish Embryos as Teratogenicity Screens : A
Comparison of Embryotoxicity between Fish and
Birds
Ecotoxicology and Environmental Safety 1990 2018/12/05
魚類 Brachydanio rerio (Zebrafish) EC50 7 days 0.006 mg/L 4 OECD SIDS (HPVC) 4 Van Leeuwen CJ, Grootelaar EMM, and Niebeek G Fish Embryos as Teratogenicity Screens : A
Comparison of Embryotoxicity between Fish and
Birds
Ecotoxicology and Environmental Safety 1990 2018/12/05
魚類 Brachydanio rerio (Zebrafish) mortality LOEC 7 days 0.001 mg/L 4 OECD SIDS (HPVC) 4 Van Leeuwen CJ, Grootelaar EMM, and Niebeek G Fish Embryos as Teratogenicity Screens : A
Comparison of Embryotoxicity between Fish and
Birds
Ecotoxicology and Environmental Safety 1990 2018/12/05
魚類 Oncorhynchus mykiss (Rainbow trout) EC50 60 days 0.00064 mg/L 4 OECD SIDS (HPVC) 4 Van leeuwen CJ, Espeldoorn A and Mol F Aquatic toxicological aspects of dithiocarbamates
and related compounds. III. Embryolarval studies
with rainbow trout (Salmo Gairdneri)
Aquatic Toxicology 1986 2018/12/05
魚類 Pimephales promelas (Fathead minnow) EGGSLAID, SURVIVE NOEL 210 days 1.1 ppb 3 USEPA Pesticide Ecotoxicity Database N. Federoff 2011 2018/03/07
魚類 Lepomis macrochirus (Bluegill) NOEL 96 hours 100 ppb 3 USEPA Pesticide Ecotoxicity Database McCann/Bascietto 1972 2018/03/07
魚類 Oncorhynchus mykiss (Rainbow trout) NOEL 96 hours 11 ppb 3 USEPA Pesticide Ecotoxicity Database N. Federoff 2012 2018/03/07
魚類 Oncorhynchus mykiss (Rainbow trout) SURVIVE, GROWTH LOEC 28 days 25 ppb 3 USEPA Pesticide Ecotoxicity Database N. Federoff 2012 2018/03/07
魚類 Pimephales promelas (Fathead minnow) EGGSLAID, SURVIVE LOEC 210 days 2.2 ppb 3 USEPA Pesticide Ecotoxicity Database N. Federoff 2011 2018/03/07
魚類 Oncorhynchus mykiss (Rainbow trout) SURVIVE, GROWTH NOEL 28 days 15 ppb 3 USEPA Pesticide Ecotoxicity Database N. Federoff 2012 2018/03/07
魚類 Oryzias latipes (Japanese medaka) LOEC 96 hours 0.2 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute toxicity test of Bis (dimethylthiocarbamoyl)
disulfide (CAS No.:137-26-8) in fish (Oryzias
latipes)
2008 2016/02/22
魚類 Oncorhynchus mykiss (Rainbow trout) Growth LOEC 60 days 0.56 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
b Van Leeuwen, C.J., A. Espeldoorn, and F. Mol
(1986)
Aquatic Toxicological Aspects of Dithiocarbamates
and Related Compounds. III. Embryolarval Studies
with Rainbow Trout (Salmo gairdneri).
Aquat.Toxicol. 1986 2016/03/07
魚類 Brachydanio rerio (Zebrafish) Mortality LOEC 7 days 1 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
b Van Leeuwen, C.J., E.M.M. Grootelaar, and G.
Niebeek
Fish Embryos as Teratogenicity Screens: A
Comparison of Embryotoxicity Between Fish and
Birds.
Ecotoxicol.Environ.Saf. 1990 2016/03/07
魚類 Brachydanio rerio (Zebrafish) LC50 7 days 0.034 mg/L 4 OECD SIDS (HPVC) 4 Van Leeuwen CJ, Grootelaar EMM, and Niebeek G Fish Embryos as Teratogenicity Screens : A
Comparison of Embryotoxicity between Fish and
Birds
Ecotoxicology and Environmental Safety 1990 2016/02/22
魚類 Oncorhynchus mykiss (Rainbow trout) EC50 60 days 0.00064 mg/L 4 OECD SIDS (HPVC) 4 Van leeuwen CJ, Espeldoorn A and Mol F Aquatic toxicological aspects of dithiocarbamates
and related compounds. III. Embryolarval studies
with rainbow trout (Salmo Gairdneri)
Aquatic Toxicology 1986 2016/02/22
魚類 Oryzias latipes (Japanese medaka) mortality NOEC 96 hours 0.076 mg/L 4 OECD SIDS (HPVC) 1 National Institute of Environmental Research
(NIER), Korea
Acute toxicity test of Bis (dimethylthiocarbamoyl)
disulfide (CAS No.:137-26-8) in fish (Oryzias
latipes)
2008 2025/05/02
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 60 days 0.0011 mg/L 4 OECD SIDS (HPVC) 4 Van leeuwen CJ, Espeldoorn A and Mol F Aquatic toxicological aspects of dithiocarbamates
and related compounds. III. Embryolarval studies
with rainbow trout (Salmo Gairdneri)
Aquatic Toxicology 1986 2016/02/22
魚類 Brachydanio rerio (Zebrafish) mortality LOEC 7 days 0.001 mg/L 4 OECD SIDS (HPVC) 4 Van Leeuwen CJ, Grootelaar EMM, and Niebeek G Fish Embryos as Teratogenicity Screens : A
Comparison of Embryotoxicity between Fish and
Birds
Ecotoxicology and Environmental Safety 1990 2016/02/22
魚類 Brachydanio rerio (Zebrafish) EC50 7 days 0.006 mg/L 4 OECD SIDS (HPVC) 4 Van Leeuwen CJ, Grootelaar EMM, and Niebeek G Fish Embryos as Teratogenicity Screens : A
Comparison of Embryotoxicity between Fish and
Birds
Ecotoxicology and Environmental Safety 1990 2016/02/22
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LOEC 60 days 0.001 mg/L 4 OECD SIDS (HPVC) 4 Van leeuwen CJ, Espeldoorn A and Mol F Aquatic toxicological aspects of dithiocarbamates
and related compounds. III. Embryolarval studies
with rainbow trout (Salmo Gairdneri)
Aquatic Toxicology 1986 2016/02/22