生態影響に係る有害性情報


CAS登録番号 CAS RN ® ： 3766-81-2
官報公示整理番号　METI No. ： 3-2211
物質名 test material ： Ｎ－メチルカルバミン酸２－ｓｅｃ－ブチルフェニル　／2-sec-butylphenyl methylcarbamate
水溶解度 water solubility ： 420mg/L (推計値 estimated)
LogKow ： 2.78 (実測値 measured)
備考 remarks ：
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書） / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし　4:情報が少なく評価不能
日本環境省　化学物質の環境リスク評価（生態リスク初期評価） A：試験は信頼できる　B：試験は条件付きで信頼できる　C：試験の信頼性は低い　D：信頼性の判定不可　E：信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり　Supplemental:条件付きで信頼性あり　Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり：○
なし：×		 情報源 情報源による
信頼性評価**		 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value		 exposure
duration
unit		 toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material		 original work type original work
reliability rank		 author title referenced journal publication year Information
update date
藻類 Pseudokirchneriella subcapitata ErC50 72 hours 41500 μg/L 2 日本環境省　農薬登録保留基準（水産動植物） 環境省 水産動植物の被害防止に係る農薬登録保留基準の設定に関する資料 2016/02/17
藻類 Pseudokirchneriella subcapitata ErC50 72 hours 33000 μg/L 2 日本環境省　農薬登録保留基準（水産動植物） 環境省 水産動植物の被害防止に係る農薬登録保留基準の設定に関する資料 環境庁(1998)：平成9 年度生態影響試験報告書 2016/02/17
藻類 Pseudokirchneriella subcapitata NOECr 72 hours 2980 μg/L 2 日本環境省　農薬登録保留基準（水産動植物） 環境省 水産動植物の被害防止に係る農薬登録保留基準の設定に関する資料 2016/02/17
藻類 Pseudokirchneriella subcapitata NOECr 72 hours 1800 μg/L 2 日本環境省　農薬登録保留基準（水産動植物） 環境省 水産動植物の被害防止に係る農薬登録保留基準の設定に関する資料 環境庁(1998)：平成9 年度生態影響試験報告書 2016/02/17
甲殻類 Daphnia magna Reproduction LOEC 13 days 25～50 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Matsumoto,K.I., M. Hosokawa, K. Kuroda, and G.
Endo		 Toxicity of Agricultural Chemicals in Daphnia
magna		 Osaka City Med. J.55(2): 89-97 2009 2016/03/25
甲殻類 Daphnia magna Mortality LC50 8 days 37.5 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Matsumoto,K.I., M. Hosokawa, K. Kuroda, and G.
Endo		 Toxicity of Agricultural Chemicals in Daphnia
magna		 Osaka City Med. J.55(2): 89-97 2009 2016/03/25
甲殻類 Daphnia magna Physiology LC50 2 days 35 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Matsumoto,K.I., M. Hosokawa, K. Kuroda, and G.
Endo		 Toxicity of Agricultural Chemicals in Daphnia
magna		 Osaka City Med. J.55(2): 89-97 2009 2016/03/25
甲殻類 Daphnia magna Reproduction LOEC 13 days 25～50 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Matsumoto,K.I., M. Hosokawa, K. Kuroda, and G.
Endo		 Toxicity of Agricultural Chemicals in Daphnia
magna		 Osaka City Med. J.55(2): 89-97 2009 2016/03/25
甲殻類 Daphnia magna Mortality LC50 2 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatakeyama,S., and Y. Sugaya A Freshwater Shrimp (Paratya compressa improvisa)
as a Sensitive Test Organism to Pesticides		 Environ. Pollut.59(4): 325-336 1989 2016/03/25
甲殻類 Daphnia magna Physiology LC50 1 days 37 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Matsumoto,K.I., M. Hosokawa, K. Kuroda, and G.
Endo		 Toxicity of Agricultural Chemicals in Daphnia
magna		 Osaka City Med. J.55(2): 89-97 2009 2016/03/25
甲殻類 Daphnia magna Mortality LC50 48 hours 0.0992 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Peter C. von der Ohe, Ralph Kühne, Ralf-Uwe Ebert,
Rolf Altenburger, Matthias Liess, and Gerrit
Schüürmann		 Structural Alerts-A New Classification Model to
Discriminate Excess Toxicity from Narcotic
Effect Levels of Organic Compounds in the
Acute Daphnid Assay		 2005 2016/02/08
甲殻類 Daphnia magna 遊泳阻害 EC50 48 hours 10.2 μg/L 2 日本環境省　農薬登録保留基準（水産動植物） 環境省 水産動植物の被害防止に係る農薬登録保留基準の設定に関する資料 2016/02/17
甲殻類 Daphnia magna 遊泳阻害 EC50 48 hours 14.4 μg/L 2 日本環境省　農薬登録保留基準（水産動植物） 環境省 水産動植物の被害防止に係る農薬登録保留基準の設定に関する資料 環境庁(1998)：平成9 年度生態影響試験報告書 2016/02/17
甲殻類 Daphnia magna 遊泳阻害 EC50 48 hours 36.7 μg/L 2 日本環境省　農薬登録保留基準（水産動植物） 環境省 水産動植物の被害防止に係る農薬登録保留基準の設定に関する資料 2016/02/17
魚類 Cyprinus carpio (Carp) Population NOEC 21 days 750 AI g/ha 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Koesoemadinata,S. Aquatic Toxicology of Selected Rice Insecticides,
with Special Reference to Their Effects on Fish
Culture in West Java, Indonesia		 Ph.D.Thesis, University of Stirling, Stirling, UK:
379 p.		 1990 2016/03/25
魚類 Cyprinus carpio (Carp) Growth NOEC 25 days 1500 AI g/ha 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Koesoemadinata,S. Aquatic Toxicology of Selected Rice Insecticides,
with Special Reference to Their Effects on Fish
Culture in West Java, Indonesia		 Ph.D.Thesis, University of Stirling, Stirling, UK:
379 p.		 1990 2016/03/25
魚類 Cyprinus carpio (Carp) Mortality LC50 2 days 1600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Li,G.C., and C.Y. Chen Study on the Acute Toxicities of Commonly Used
Pesticides to Two Kinds of Fish		 KO Hsueh Fa Chan Yueh Kan9(2): 146-152 1981 2016/03/25
魚類 Cyprinus carpio (Carp) Mortality LC50 4 days 1700 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,F. Evaluating Acute Toxicity of Pesticides to
Aquatic Organisms: Carp, Mosquito Fish and
Daphnids		 Zhiwu Baohu Xuehui Huikan (Plant Prot. Bull.
(Taichung))29(4): 385-396		 1987 2016/03/25
魚類 Cyprinus carpio (Carp) Mortality NOEC 25 days 1500 AI g/ha 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Koesoemadinata,S. Aquatic Toxicology of Selected Rice Insecticides,
with Special Reference to Their Effects on Fish
Culture in West Java, Indonesia		 Ph.D.Thesis, University of Stirling, Stirling, UK:
379 p.		 1990 2016/03/25
魚類 Cyprinus carpio (Carp) Growth NOEC 21 days 750 AI g/ha 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Koesoemadinata,S. Aquatic Toxicology of Selected Rice Insecticides,
with Special Reference to Their Effects on Fish
Culture in West Java, Indonesia		 Ph.D.Thesis, University of Stirling, Stirling, UK:
379 p.		 1990 2016/03/25
魚類 Cyprinus carpio (Carp) Growth NOEC 25 days 1500 AI g/ha 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Koesoemadinata,S. Aquatic Toxicology of Selected Rice Insecticides,
with Special Reference to Their Effects on Fish
Culture in West Java, Indonesia		 Ph.D.Thesis, University of Stirling, Stirling, UK:
379 p.		 1990 2016/03/25
魚類 Cyprinus carpio (Carp) Growth NOEC 25 days 1500 AI g/ha 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Koesoemadinata,S. Aquatic Toxicology of Selected Rice Insecticides,
with Special Reference to Their Effects on Fish
Culture in West Java, Indonesia		 Ph.D.Thesis, University of Stirling, Stirling, UK:
379 p.		 1990 2016/03/25
魚類 Cyprinus carpio (Carp) Mortality LC50 2 days 7500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Koesoemadinata,S. Aquatic Toxicology of Selected Rice Insecticides,
with Special Reference to Their Effects on Fish
Culture in West Java, Indonesia		 Ph.D.Thesis, University of Stirling, Stirling, UK:
379 p.		 1990 2016/03/25
魚類 Cyprinus carpio (Carp) Mortality LC50 1 days 8300 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Koesoemadinata,S. Aquatic Toxicology of Selected Rice Insecticides,
with Special Reference to Their Effects on Fish
Culture in West Java, Indonesia		 Ph.D.Thesis, University of Stirling, Stirling, UK:
379 p.		 1990 2016/03/25
魚類 Cyprinus carpio (Carp) Growth LOEC 25 days 1500 AI g/ha 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Koesoemadinata,S. Aquatic Toxicology of Selected Rice Insecticides,
with Special Reference to Their Effects on Fish
Culture in West Java, Indonesia		 Ph.D.Thesis, University of Stirling, Stirling, UK:
379 p.		 1990 2016/03/25
魚類 Cyprinus carpio (Carp) Population LOEC 25 days 1500 AI g/ha 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Koesoemadinata,S. Aquatic Toxicology of Selected Rice Insecticides,
with Special Reference to Their Effects on Fish
Culture in West Java, Indonesia		 Ph.D.Thesis, University of Stirling, Stirling, UK:
379 p.		 1990 2016/03/25
魚類 Cyprinus carpio (Carp) Biochemical 3 days 50～100 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Ariyoshi,T., S. Shiiba, H. Hasegawa, and K.
Arizono		 Effects of the Environmental Pollutants on Heme
Oxygenase Activity and Cytochrome P-450 Content
in Fish		 Bull. Environ. Contam. Toxicol.44(2): 189-196 1990 2016/03/25
魚類 Cyprinus carpio (Carp) Population NOEC 25 days 750 AI g/ha 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Koesoemadinata,S. Aquatic Toxicology of Selected Rice Insecticides,
with Special Reference to Their Effects on Fish
Culture in West Java, Indonesia		 Ph.D.Thesis, University of Stirling, Stirling, UK:
379 p.		 1990 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality 5 days 320 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kubota,S.S., and T. Ochiai Studies on Toxic Effects of Pesticides on Fish -
III. Effect of Benthiocarb on the Toxicity of
the Other Pesticides		 Bull. Fac. Fish. Mie Univ.6:119-128 1979 2016/03/25
魚類 Cyprinus carpio (Carp) Biochemical EC50 4 days 171.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chen,C., Y. Wang, X. Zhao, Q. Wang, and Y. Qian The Combined Toxicity Assessment of Carp
(Cyprinus carpio) Acetylcholinesterase Activity
by Binary Mixtures of Chlorpyrifos and
Four Other Insecticides		 Ecotoxicology23:221-228 2014 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality 5 days 320 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kubota,S.S., and T. Ochiai Studies on Toxic Effects of Pesticides on Fish -
III. Effect of Benthiocarb on the Toxicity of
the Other Pesticides		 Bull. Fac. Fish. Mie Univ.6:119-128 1979 2016/03/25
魚類 Cyprinus carpio (Carp) Growth NOEC 21 days 750 AI g/ha 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Koesoemadinata,S. Aquatic Toxicology of Selected Rice Insecticides,
with Special Reference to Their Effects on Fish
Culture in West Java, Indonesia		 Ph.D.Thesis, University of Stirling, Stirling, UK:
379 p.		 1990 2016/03/25
魚類 Cyprinus carpio (Carp) Growth NOEC 21 days 750 AI g/ha 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Koesoemadinata,S. Aquatic Toxicology of Selected Rice Insecticides,
with Special Reference to Their Effects on Fish
Culture in West Java, Indonesia		 Ph.D.Thesis, University of Stirling, Stirling, UK:
379 p.		 1990 2016/03/25
魚類 Cyprinus carpio (Carp) Mortality LC50 2 days 12600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Li,G.C., and C.Y. Chen Study on the Acute Toxicities of Commonly Used
Pesticides to Two Kinds of Fish		 KO Hsueh Fa Chan Yueh Kan9(2): 146-152 1981 2016/03/25
魚類 Cyprinus carpio (Carp) Biochemical 3 days 100 mg/kg bdwt 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Ariyoshi,T., S. Shiiba, H. Hasegawa, and K.
Arizono		 Profile of Metal-Binding Proteins and Heme
Oxygenase in Red Carp Treated With Heavy Metals,
Pesticides and Surfactants		 Bull. Environ. Contam. Toxicol.44(4): 643-649 1990 2016/03/25
魚類 Cyprinus carpio (Carp) Mortality NOEC 21 days 750 AI g/ha 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Koesoemadinata,S. Aquatic Toxicology of Selected Rice Insecticides,
with Special Reference to Their Effects on Fish
Culture in West Java, Indonesia		 Ph.D.Thesis, University of Stirling, Stirling, UK:
379 p.		 1990 2016/03/25
魚類 Cyprinus carpio (Carp) Mortality LC50 4 days 5800 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Koesoemadinata,S. Aquatic Toxicology of Selected Rice Insecticides,
with Special Reference to Their Effects on Fish
Culture in West Java, Indonesia		 Ph.D.Thesis, University of Stirling, Stirling, UK:
379 p.		 1990 2016/03/25
魚類 Poecilia reticulata (Guppy) Mortality LC50 2 days 800 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Tejada,A.W., C.M. Bajet, M.G. Magbauna, N.B.
Gambalan, L.C. Araez, and E.D. Magallona		 Toxicity of Pesticides to Target and Non-Target
Fauna of the Lowland Rice Ecosystem		 In: B.Widianarko, K.Vink, and N.M.Van Straalen
(Eds.), Environmental Toxicology in South East
Asia, VU University Press, Amsterdam:89-103		 1994 2016/03/25
魚類 Cyprinus carpio (Carp) Mortality 4 days 400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chen,C., Y. Wang, X. Zhao, Q. Wang, and Y. Qian The Combined Toxicity Assessment of Carp
(Cyprinus carpio) Acetylcholinesterase Activity
by Binary Mixtures of Chlorpyrifos and
Four Other Insecticides		 Ecotoxicology23:221-228 2014 2016/03/25
魚類 Poecilia reticulata (Guppy) Mortality LC50 1 days 1850 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Tejada,A.W., C.M. Bajet, M.G. Magbauna, N.B.
Gambalan, L.C. Araez, and E.D. Magallona		 Toxicity of Pesticides to Target and Non-Target
Fauna of the Lowland Rice Ecosystem		 In: B.Widianarko, K.Vink, and N.M.Van Straalen
(Eds.), Environmental Toxicology in South East
Asia, VU University Press, Amsterdam:89-103		 1994 2016/03/25
魚類 Cyprinus carpio (Carp) Mortality LC50 3 days 6600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Koesoemadinata,S. Aquatic Toxicology of Selected Rice Insecticides,
with Special Reference to Their Effects on Fish
Culture in West Java, Indonesia		 Ph.D.Thesis, University of Stirling, Stirling, UK:
379 p.		 1990 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 48 hours 9.92 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) - Biodegradation and Bioaccumulation Data of
Existing Chemicals Based on the CSCL Japan		 1992 2016/02/08
魚類 Cyprinus carpio (Carp) 死亡 LC50 96 hours 25200 μg/L 2 日本環境省　農薬登録保留基準（水産動植物） 環境省 水産動植物の被害防止に係る農薬登録保留基準の設定に関する資料 2016/02/17
魚類 Oryzias latipes (Japanese medaka) 死亡 LC50 96 hours 9780 μg/L 2 日本環境省　農薬登録保留基準（水産動植物） 環境省 水産動植物の被害防止に係る農薬登録保留基準の設定に関する資料 環境庁（1998）：平成9 年度生態影響調査報告書 2016/02/17