化学物質有害性情報データベース 物質情報

CAS 登録番号 CAS RN® ： 532321
官報公示整理番号　METI No. ： 3-1823
物質名 test material ： ナトリウム＝ベンゾアート　／Sodium benzoate
水溶解度 water solubility ： 5.5mg/L (実測値 measured)
LogKow ： -2.27 (推計値 estimated)
備考 remarks ：
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【注意事項】
* 化学物質有害性情報データベース情報更新日が2019年9月以前はRead-acrossデータでも○としていないので、毒性値の取り扱いには注意が必要である。

　　　 　　　 　　　 　　　 　　　 　　　
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) Read-across * QSAR GLP 設定濃度 実測濃度 情報源 情報源による信頼性評価 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure duration value exposure duration unit toxicity value toxicity unit Read-across QSAR GLPnominal concentration measured concentrationoriginal work type original work reliability rankauthor title referenced journal publication year Information update date
藻類 Pseudokirchneriella subcapitata Yield inhibition EyC50 72 hours 24.8 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2010 2017/02/27
藻類 Pseudokirchneriella subcapitata growth rate EC50 72 hours >30.5 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2010 2017/02/27
藻類 Pseudokirchneriella subcapitata growth rate NOEC 72 hours 0.09 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2010 2017/02/27
藻類 Pseudokirchneriella subcapitata Yield inhibition NOEyC 72 hours 0.09 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2010 2017/02/27
藻類 Pseudokirchneriella subcapitata growth rate EC10 72 hours 6.5 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 2010 2017/02/27
甲殻類 Daphnia magna Mortality LC50 4 days >100000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Ewell,W.S., J.W. Gorsuch, R.O. Kringle, K.A. Robillard, and R.C. Spiegel Simultaneous Evaluation of the Acute Effects of Chemicals on Seven Aquatic Species Environ. Toxicol. Chem.5(9): 831-840 1986 2017/03/15
甲殻類 Daphnia magna Physiology NOEC 2 days <650000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Anderson,B.G. The Toxicity Thresholds of Various Sodium Salts Determined by the Use of Daphnia magna Sewage Works J.18(1): 82-87 1946 2017/03/15
甲殻類 Daphnia magna Mortality LC50 4 days >100000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Ewell,W.S., J.W. Gorsuch, R.O. Kringle, K.A. Robillard, and R.C. Spiegel Simultaneous Evaluation of the Acute Effects of Chemicals on Seven Aquatic Species Environ. Toxicol. Chem.5(9): 831-840 1986 2016/03/25
甲殻類 Daphnia magna Physiology NOEC 2 days <650000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Anderson,B.G. The Toxicity Thresholds of Various Sodium Salts Determined by the Use of Daphnia magna Sewage Works J.18(1): 82-87 1946 2016/03/25
甲殻類 Daphnia magna LC50 96 hours >100 mg/L 15 WHO/IPCS CICAD Ewell WS, Gorsuch JW, Kringle RO, Robillard KA, Spiegel RC Simultaneous evaluation of the acute effects of chemicals on seven aquatic species. Environmental toxicology and chemistry 1986 2017/03/18
甲殻類 Daphnia magna mortality EC50 96 hours >100 mg/L 4 OECD SIDS (HPVC) 2 Ewell, W.S. et al. Environ. Toxicol. Chem. 1986 2017/02/21
甲殻類 Daphnia magna EC50 48 hours <650 mg/L 4 OECD SIDS (HPVC) Ewell, W.S. et al. Environ. Toxicol. Chem. 1986 2017/02/21
甲殻類 Daphnia magna EC50 48 hours <650 mg/L 11 Japan チャレンジプログラム Anderson, B.G Sewage Works J. 18 1946 2017/01/26
甲殻類 Daphnia magna EC50 96 hours >100 mg/L 11 Japan チャレンジプログラム Ewell, W.S. et al Environ. Toxicol. Chem. 5 1986 2017/01/26
甲殻類 Daphnia magna mortality LC50 96 hours >100 mg/L 12 ECHA Information on Registered Substances 2 publication 1986 2017/02/27
甲殻類 Daphnia magna mortality LC50 96 hours >100 mg/L 12 ECHA Information on Registered Substances 2 publication 1986 2017/02/27
魚類 Danio rerio (Zebrafish) Behavior EC50 2 days 68500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bichara,D., N.B. Calcaterra, S. Arranz, P. Armas, and S.H. Simonetta Set-up of an Infrared Fast Behavioral Assay Using Zebrafish (Danio rerio) Larvae, and Its Application in Compound Biotoxicity Screening J. Appl. Toxicol.34:214-219 2014 2017/03/15
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days >100000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Ewell,W.S., J.W. Gorsuch, R.O. Kringle, K.A. Robillard, and R.C. Spiegel Simultaneous Evaluation of the Acute Effects of Chemicals on Seven Aquatic Species Environ. Toxicol. Chem.5(9): 831-840 1986 2017/03/15
魚類 Danio rerio (Zebrafish) Mortality LC50 2 days 461000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bichara,D., N.B. Calcaterra, S. Arranz, P. Armas, and S.H. Simonetta Set-up of an Infrared Fast Behavioral Assay Using Zebrafish (Danio rerio) Larvae, and Its Application in Compound Biotoxicity Screening J. Appl. Toxicol.34:214-219 2014 2017/03/15
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 484000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Geiger,D.L., C.E. Northcott, D.J. Call, and L.T. Brooke Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales promelas), Volume II Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI:326 p. 1985 2017/03/15
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 484000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Geiger,D.L., C.E. Northcott, D.J. Call, and L.T. Brooke Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales promelas), Volume II Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI:326 p. 1985 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 2 days 461000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bichara,D., N.B. Calcaterra, S. Arranz, P. Armas, and S.H. Simonetta Set-up of an Infrared Fast Behavioral Assay Using Zebrafish (Danio rerio) Larvae, and Its Application in Compound Biotoxicity Screening J. Appl. Toxicol.34:214-219 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days >100000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Ewell,W.S., J.W. Gorsuch, R.O. Kringle, K.A. Robillard, and R.C. Spiegel Simultaneous Evaluation of the Acute Effects of Chemicals on Seven Aquatic Species Environ. Toxicol. Chem.5(9): 831-840 1986 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior EC50 2 days 68500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bichara,D., N.B. Calcaterra, S. Arranz, P. Armas, and S.H. Simonetta Set-up of an Infrared Fast Behavioral Assay Using Zebrafish (Danio rerio) Larvae, and Its Application in Compound Biotoxicity Screening J. Appl. Toxicol.34:214-219 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours >100 mg/L 15 WHO/IPCS CICAD Ewell WS, Gorsuch JW, Kringle RO, Robillard KA, Spiegel RC Simultaneous evaluation of the acute effects of chemicals on seven aquatic species. Environmental toxicology and chemistry 1986 2017/03/18
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours 484 mg/L 15 WHO/IPCS CICAD Geiger DL, Northcott CE, Call DJ, Brooke LT Acute toxicities of organic chemicals to fathead minnows (Pimephales promelas). Vol. II. Superior, WI, University of Wisconsin 1985 2017/03/18
魚類 Pimephales promelas (Fathead minnow) EC50 96 hours 484 mg/L 4 OECD SIDS (HPVC) 1 Geiger, D.L. et al. Acute toxicities of organic chemicals to fathead minnows (Pimephales promelas) Vol. 2, University of Wisconsin 1985 2017/02/21
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours >100 mg/L 4 OECD SIDS (HPVC) 2 Ewell, W.S. et al Environ. Toxicol. Chem. 1986 2017/02/21
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours >100 mg/L 11 Japan チャレンジプログラム Ewell, W.S. et al Environ. Toxicol. Chem. 5 1986 2017/01/26
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 96 hours 574 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Russom, C.L., Bradbury, S.P., Broderius, S.J., Drummond, R.A. and Hammermeister, D.E. PREDICTING MODES OF TOXIC ACTION FROM CHEMICAL STRUCTURE: ACUTE TOXICITY IN THE FATHEAD MINNOW (PIMEPHALES PROMELAS) Environmental Toxicology and Chemistry, Vol. 16, No. 5, pp. 948–967. 1997 2017/03/22
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 484 mg/L × 12 ECHA Information on Registered Substances 2 Geiger D. L., Brooke L. T. and Call D. J. Acute toxicities of organic chemicals to fathead minnows (Pimephales promelas) University of Wisconsin. 1985 2017/02/27
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours >100 mg/L 12 ECHA Information on Registered Substances 2 publication 1986 2017/02/27
魚類 Pimephales promelas (Fathead minnow) NOEC 96 hours >245 mg/L 4 OECD SIDS (HPVC) 1 Geiger, D.L. et al. Acute toxicities of organic chemicals to fathead minnows (Pimephales promelas), Vol. 2, University of Wisconsin 1985 2017/02/21
魚類 Danio rerio (Zebrafish) mortality LC50 24 hours 1400～1500 12 ECHA Information on Registered Substances 2 publication 2007 2017/02/27
魚類 Danio rerio (Zebrafish) based on gut abnormalities, malformation of pronephros, edema in the pericardial sac and deformed hatching gland as well as reduced reaction on tactile stimulus NOEC 144 hours 10 mg/L 12 ECHA Information on Registered Substances 2 publication 2007 2017/02/27
魚類 Pimephales promelas (Fathead minnow) mortality NOEC 96 hours 392.5 mg/L × 12 ECHA Information on Registered Substances 2 Geiger D. L., Brooke L. T. and Call D. J. Acute toxicities of organic chemicals to fathead minnows (Pimephales promelas) University of Wisconsin. 1985 2017/02/27
魚類 Danio rerio (Zebrafish) based on gut abnormalities, malformation of pronephros, edema in the pericardial sac and deformed hatching gland as well as reduced reaction on tactile stimulus LOEC 144 hours 100 mg/L 12 ECHA Information on Registered Substances 2 publication 2007 2017/02/27
魚類 Danio rerio (Zebrafish) based on gut abnormalities, malformation of pronephros, edema in the pericardial sac and deformed hatching gland as well as reduced reaction on tactile stimulus NOEC 144 hours 10 mg/L 12 ECHA Information on Registered Substances 2 publication 2007 2017/02/27
魚類 Danio rerio (Zebrafish) mortality LC50 24 hours 1400～1500 12 ECHA Information on Registered Substances 2 publication 2007 2017/02/27
魚類 Danio rerio (Zebrafish) based on gut abnormalities, malformation of pronephros, edema in the pericardial sac and deformed hatching gland as well as reduced reaction on tactile stimulus LOEC 144 hours 100 mg/L 12 ECHA Information on Registered Substances 2 publication 2007 2017/02/27