生態影響に係る有害性情報


CAS登録番号 CAS RN ® ： 556-67-2
官報公示整理番号　METI No. ： 7-475
物質名 test material ： ２，２，４，４，６，６，８，８－オクタメチルシクロテトラシロキサン　／2,2,4,4,6,6,8,8-Octamethylcyclotetrasiloxane
水溶解度 water solubility ： 0.005mg/L (推計値 estimated)
LogKow ： 6.74 (実測値 measured)
備考 remarks ：
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書） / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし　4:情報が少なく評価不能
日本環境省　化学物質の環境リスク評価（生態リスク初期評価） A：試験は信頼できる　B：試験は条件付きで信頼できる　C：試験の信頼性は低い　D：信頼性の判定不可　E：信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり　Supplemental:条件付きで信頼性あり　Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり：○
なし：×		 情報源 情報源による
信頼性評価**		 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value		 exposure
duration
unit		 toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material		 original work type original work
reliability rank		 author title referenced journal publication year Information
update date
藻類 Pseudokirchneriella subcapitata cell density EC50 96 hours >22 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 1990 2017/03/06
藻類 Pseudokirchneriella subcapitata cell density EC50 96 hours >22 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 1990 2017/03/06
藻類 Anabaena flos-aquae Ash free weight and filament count EL50 14 days >2000 mg/L × 12 ECHA Information on Registered Substances 4 Firmin, R. et al. The Environmental Impact of|Organosilicon Compounds on the Aquatic Biosphere Ecotoxicological Testing for the Marine Environment, 1984. Persoone, G. et. al. (Eds). State Univ. Ghent and Inst. Mar. Scient. Res., Bredene, Belgium, Vol. 1, 789 p. 1984 2017/02/09
藻類 Pseudokirchneriella subcapitata cell density NOEC 96 hours <22 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 1990 2017/03/06
藻類 Pseudokirchneriella subcapitata cell density NOEC 96 hours <22 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 1990 2017/03/06
甲殻類 Daphnia magna 93 days 5.5 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Sousa,J.V., P.C. McNamara, A.E. Putt, M.W. Machado, D.C. Surprenant, J.L. Hamelink, and D.J. Kent Effects of Octamethylcyclotetrasiloxane (OMCTS) on Freshwater and Marine Organisms Environ. Toxicol. Chem.14(10): 1639-1647 1995 2017/03/15
甲殻類 Daphnia magna Reproduction NOEC 21 days 1.7～15 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Sousa,J.V., P.C. McNamara, A.E. Putt, M.W. Machado, D.C. Surprenant, J.L. Hamelink, and D.J. Kent Effects of Octamethylcyclotetrasiloxane (OMCTS) on Freshwater and Marine Organisms Environ. Toxicol. Chem.14(10): 1639-1647 1995 2017/03/15
甲殻類 Daphnia magna Physiology NOEC 2 days 15 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Sousa,J.V., P.C. McNamara, A.E. Putt, M.W. Machado, D.C. Surprenant, J.L. Hamelink, and D.J. Kent Effects of Octamethylcyclotetrasiloxane (OMCTS) on Freshwater and Marine Organisms Environ. Toxicol. Chem.14(10): 1639-1647 1995 2017/03/15
甲殻類 Daphnia magna No Group Code 93 days 5.5 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Sousa,J.V., P.C. McNamara, A.E. Putt, M.W. Machado, D.C. Surprenant, J.L. Hamelink, and D.J. Kent Effects of Octamethylcyclotetrasiloxane (OMCTS) on Freshwater and Marine Organisms Environ. Toxicol. Chem.14(10): 1639-1647 1995 2016/03/25
甲殻類 Daphnia magna Physiology NOEC 2 days 15 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Sousa,J.V., P.C. McNamara, A.E. Putt, M.W. Machado, D.C. Surprenant, J.L. Hamelink, and D.J. Kent Effects of Octamethylcyclotetrasiloxane (OMCTS) on Freshwater and Marine Organisms Environ. Toxicol. Chem.14(10): 1639-1647 1995 2016/03/25
甲殻類 Daphnia magna Reproduction NOEC 21 days 1.7～15 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Sousa,J.V., P.C. McNamara, A.E. Putt, M.W. Machado, D.C. Surprenant, J.L. Hamelink, and D.J. Kent Effects of Octamethylcyclotetrasiloxane (OMCTS) on Freshwater and Marine Organisms Environ. Toxicol. Chem.14(10): 1639-1647 1995 2016/03/25
甲殻類 Daphnia magna Physiology 21 days 1.7～15 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Sousa,J.V., P.C. McNamara, A.E. Putt, M.W. Machado, D.C. Surprenant, J.L. Hamelink, and D.J. Kent Effects of Octamethylcyclotetrasiloxane (OMCTS) on Freshwater and Marine Organisms Environ. Toxicol. Chem.14(10): 1639-1647 1995 2016/03/25
甲殻類 Daphnia magna EC100 24 hours 314 mg/L 12 ECHA Information on Registered Substances 4 company data 1998 2017/03/06
甲殻類 Daphnia magna EC50 24 hours 25.2 mg/L 12 ECHA Information on Registered Substances 4 company data 1998 2017/03/06
甲殻類 Daphnia magna EC0 24 hours 3.1 mg/L 12 ECHA Information on Registered Substances 4 company data 1998 2017/03/06
甲殻類 Daphnia magna mobility EC50 48 hours >15 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 1990 2017/03/06
甲殻類 Daphnia magna reproduction and mortality NOEC 21 days 7.9 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 1990 2017/03/06
甲殻類 Daphnia magna mortality LOEC 21 days 15 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 1990 2017/03/06
甲殻類 Daphnia magna mortality EC50 21 days >15 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 1990 2017/03/06
甲殻類 Daphnia magna mobility NOEC 48 hours >=15 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 1990 2017/03/06
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 14 days 10 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Sousa,J.V., P.C. McNamara, A.E. Putt, M.W. Machado, D.C. Surprenant, J.L. Hamelink, and D.J. Kent Effects of Octamethylcyclotetrasiloxane (OMCTS) on Freshwater and Marine Organisms Environ. Toxicol. Chem.14(10): 1639-1647 1995 2017/03/15
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality NOEC 14 days <=4.4 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Sousa,J.V., P.C. McNamara, A.E. Putt, M.W. Machado, D.C. Surprenant, J.L. Hamelink, and D.J. Kent Effects of Octamethylcyclotetrasiloxane (OMCTS) on Freshwater and Marine Organisms Environ. Toxicol. Chem.14(10): 1639-1647 1995 2017/03/15
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LOEC 14 days 6.9 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Sousa,J.V., P.C. McNamara, A.E. Putt, M.W. Machado, D.C. Surprenant, J.L. Hamelink, and D.J. Kent Effects of Octamethylcyclotetrasiloxane (OMCTS) on Freshwater and Marine Organisms Environ. Toxicol. Chem.14(10): 1639-1647 1995 2017/03/15
魚類 Oncorhynchus mykiss (Rainbow trout) NOEC 93 days 4.4 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Sousa,J.V., P.C. McNamara, A.E. Putt, M.W. Machado, D.C. Surprenant, J.L. Hamelink, and D.J. Kent Effects of Octamethylcyclotetrasiloxane (OMCTS) on Freshwater and Marine Organisms Environ. Toxicol. Chem.14(10): 1639-1647 1995 2017/03/15
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 14 days 10 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Sousa,J.V., P.C. McNamara, A.E. Putt, M.W. Machado, D.C. Surprenant, J.L. Hamelink, and D.J. Kent Effects of Octamethylcyclotetrasiloxane (OMCTS) on Freshwater and Marine Organisms Environ. Toxicol. Chem.14(10): 1639-1647 1995 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LOEC 14 days 6.9 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Sousa,J.V., P.C. McNamara, A.E. Putt, M.W. Machado, D.C. Surprenant, J.L. Hamelink, and D.J. Kent Effects of Octamethylcyclotetrasiloxane (OMCTS) on Freshwater and Marine Organisms Environ. Toxicol. Chem.14(10): 1639-1647 1995 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality NOEC 14 days <=4.4 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Sousa,J.V., P.C. McNamara, A.E. Putt, M.W. Machado, D.C. Surprenant, J.L. Hamelink, and D.J. Kent Effects of Octamethylcyclotetrasiloxane (OMCTS) on Freshwater and Marine Organisms Environ. Toxicol. Chem.14(10): 1639-1647 1995 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) No Group Code NOEC 93 days 4.4 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Sousa,J.V., P.C. McNamara, A.E. Putt, M.W. Machado, D.C. Surprenant, J.L. Hamelink, and D.J. Kent Effects of Octamethylcyclotetrasiloxane (OMCTS) on Freshwater and Marine Organisms Environ. Toxicol. Chem.14(10): 1639-1647 1995 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 14 days >51.7 μg/L ○ 12 ECHA Information on Registered Substances 2 study report 1991 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 96 hours >22 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 1990 2017/03/06
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 14 days 17 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 2008 2017/02/09
魚類 Lepomis macrochirus (Bluegill) mortality LL50 96 hours >1000 mg/L × 12 ECHA Information on Registered Substances 2 Firmin, R. et al. The Environmental Impact of Organosilicon Compounds on the Aquatic Biosphere Ecotoxicological Testing for the Marine Environment, 1984. Persoone, G. Et. Al. (Eds). State Univ. Ghent and Inst. Mar. Scient. Res., Bredene, Belgium, Vol. 1, 789 p. 1984 2017/03/06
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 14 days 17 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 2008 2017/02/09
魚類 Danio rerio (Zebrafish) mortality LL50 96 hours >500 mg/L × 12 ECHA Information on Registered Substances 2 Firmin, R. et al. The Environmental Impact ofOrganosilicon Compounds on the Aquatic Biosphere Ecotoxicological Testing for the Marine Environment, 1984. Persoone, G. Et. Al. (Eds). State Univ. Ghent and Inst. Mar. Scient. Res., Bredene, Belgium, Vol. 1, 789 p.Ecotoxicological Testing for the Marine Environment, 1984. Persoone, G. Et. Al. (Eds). State Univ. Ghent and Inst. Mar. Scient. Res., Bredene, Belgium, Vol. 1, 789 p. 1984 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 14 days 17 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 2008 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 14 days 17 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 2008 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 14 days 17 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 2008 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours >51.7 μg/L ○ 12 ECHA Information on Registered Substances 2 study report 1991 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 14 days 10 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 1990 2017/03/06
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LOEC 14 days 13 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 2008 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 96 hours >23 μg/L ○ 12 ECHA Information on Registered Substances 2 study report 1992 2017/03/06
魚類 Oncorhynchus mykiss (Rainbow trout) mortality NOEC 14 days 6.8 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 2008 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) mortality NOEC 14 days 6.8 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 2008 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) mortality NOEC 18 days <23 μg/L ○ 12 ECHA Information on Registered Substances 2 study report 1992 2017/03/06
魚類 Oncorhynchus mykiss (Rainbow trout) NOEC 14 days 16.9 μg/L ○ 12 ECHA Information on Registered Substances 2 study report 1991 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) mortality NOEC 18 days >=31 μg/L ○ 12 ECHA Information on Registered Substances 2 study report 1992 2017/03/06
魚類 Oncorhynchus mykiss (Rainbow trout) mortality NOEC 18 days >=31 μg/L ○ 12 ECHA Information on Registered Substances 2 study report 1992 2017/03/06
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 96 hours >23 μg/L ○ 12 ECHA Information on Registered Substances 2 study report 1992 2017/03/06
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LOEC 14 days 13 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 2008 2017/02/09
魚類 Leuciscus idus (Orfe) mortality NOELR 96 hours >1041 mg/L ○ 12 ECHA Information on Registered Substances 2 study report 1990 2017/03/06
魚類 Oncorhynchus mykiss (Rainbow trout) mortality NOEC 14 days 6.8 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 2008 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) mortality NOEC 18 days <23 μg/L ○ 12 ECHA Information on Registered Substances 2 study report 1992 2017/03/06
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 96 hours >31 μg/L ○ 12 ECHA Information on Registered Substances 2 study report 1992 2017/03/06
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 96 hours >31 μg/L ○ 12 ECHA Information on Registered Substances 2 study report 1992 2017/03/06
魚類 Oncorhynchus mykiss (Rainbow trout) mortality NOEC 96 hours >=22 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 1990 2017/03/06
魚類 Oncorhynchus mykiss (Rainbow trout) mortality NOEC 14 days 6.8 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 2008 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LOEC 14 days 13 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 2008 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) mortality NOEC 14 days 6.8 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 2008 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LOEC 14 days 13 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 2008 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LOEC 14 days 13 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 2008 2017/02/09
魚類 Oncorhynchus mykiss (Rainbow trout) mortality NOEC 14 days <=4.4 μg/L ○ 12 ECHA Information on Registered Substances 1 study report 1990 2017/03/06