【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。
| 生物種 | 学名 | 影響内容 | エンドポイント | 暴露期間(値) | 暴露期間(単位) | 毒性値 | 毒性値(単位) | 毒性値(単位)種別 | 試験中の 被験物質 濃度測定 あり：○ なし：× |
情報源 | 情報源による 信頼性評価** |
著者 | タイトル | 記載誌 | 発行年 | 情報更新日 | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| subject type | scientific name | effect | endpoint | exposure duration value |
exposure duration unit |
toxicity value | toxicity unit | toxicity unit type | Read-across* | QSAR | GLP | measurement of the test material |
original work type | original work reliability rank |
author | title | referenced journal | publication year | Information update date |
| 藻類 | Chlorella vulgaris | Population | IC50 | 5 | days | 5000000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Przytocka-Jusiak,M. | Growth and Survival of Chlorella vulgaris in high Concentrations of Nitrogen | Acta Microbiol. Pol.25(3): 287-289 | 1976 | 2016/03/25 | ||||||
| 藻類 | Scenedesmus sp. Scenedesmus quadricauda | Toxicity threshold | 192 | hours | >10000 | mg/L | 11 Japan チャレンジプログラム | Bringmann, G. and Kuhn, R. | Vom Wasser, 50 | 1978 | 2016/03/12 | ||||||||
| 甲殻類 | Daphnia magna | Physiology | EC50 | 2 | days | 3910000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Janssen,C.R., E.Q. Espiritu, and G. Persoone | Evaluation of the New "Enzymatic Inhibition" Criterion for Rapid Toxicity Testing with Daphnia magna | In: A.Soares and P.Calow (Eds.), Progress in Standardization of Aquatic Toxicity Tests, Lewis Publ.:71-81 | 1993 | 2016/03/25 | ||||||
| 甲殻類 | Daphnia magna | Behavior | EC50 | 1 | days | >10000000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Bringmann,G., and R. Kuehn | Results of Toxic Action of Water Pollutants on Daphnia magna Straus Tested by an Improved Standardized Procedure | Z. Wasser-Abwasser-Forsch.15(1): 1-6 | 1982 | 2016/03/25 | ||||||
| 甲殻類 | Daphnia magna | Biochemical | EC50 | 1 | hours | 4070000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Janssen,C.R., E.Q. Espiritu, and G. Persoone | Evaluation of the New "Enzymatic Inhibition" Criterion for Rapid Toxicity Testing with Daphnia magna | In: A.Soares and P.Calow (Eds.), Progress in Standardization of Aquatic Toxicity Tests, Lewis Publ.:71-81 | 1993 | 2016/03/25 | ||||||
| 甲殻類 | Ceriodaphnia dubia | Physiology | EC50 | 2 | days | 6573100 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Warne,M.S.J., and A.D. Schifko | Toxicity of Laundry Detergent Components to a Freshwater Cladoceran and Their Contribution to Detergent Toxicity | Ecotoxicol. Environ. Saf.44(2): 196-206 | 1999 | 2016/03/25 | ||||||
| 甲殻類 | Ceriodaphnia dubia | Physiology | EC50 | 2 | days | 6573100 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Warne,M.S.J., and A.D. Schifko | Toxicity of Laundry Detergent Components to a Freshwater Cladoceran and Their Contribution to Detergent Toxicity | Ecotoxicol. Environ. Saf.44(2): 196-206 | 1999 | 2016/03/25 | ||||||
| 甲殻類 | Daphnia magna | Physiology | LC50 | 1 | days | >10000000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Bringmann,G., and R. Kuhn | Results of the Damaging Effect of Water Pollutants on Daphnia magna (Befunde der Schadwirkung Wassergefahrdender Stoffe Gegen Daphnia magna) | TR-79-1204, Literature Research Company, Annandale, VA:26 p. | 1977 | 2016/03/25 | ||||||
| 甲殻類 | Daphnia magna | Physiology | EC50 | 1 | days | 6390000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Janssen,C.R., E.Q. Espiritu, and G. Persoone | Evaluation of the New "Enzymatic Inhibition" Criterion for Rapid Toxicity Testing with Daphnia magna | In: A.Soares and P.Calow (Eds.), Progress in Standardization of Aquatic Toxicity Tests, Lewis Publ.:71-81 | 1993 | 2016/03/25 | ||||||
| 甲殻類 | Daphnia magna | mobility | EC50 | 24 | hours | >10000 | mg/L | 12 ECHA Information on Registered Substances | 2 | publication | 1982 | 2016/02/26 | |||||||
| 甲殻類 | Daphnia magna | EC50 | 24 | hours | >10000 | mg/L | 11 Japan チャレンジプログラム | Bringmann, G. and Kuhn, R. | Zeitschrift fuer Wasser undAbwasser Forschung, 15(1), | 1982 | 2016/03/12 | ||||||||
| 甲殻類 | Daphnia magna | EC50 | 24 | hours | >10000 | mg/L | 4 OECD SIDS (HPVC) | Bringmann, G. and Kuhn, R | Zeitschrift fuer Wasser und Abwasser Forschung | 1982 | 2016/02/25 | ||||||||
| 魚類 | Cyprinus carpio (Carp) | Biochemical | 500000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Al Kahem,H.F., Z. Ahmed, and I. Alomer | A Study on the Behavioural Response and Haematological Profile of Carp, Cyprinus carpio, Exposed to Exogenous Urea | Z. Angew. Zool.80(1): 97-106 | 1994 | 2016/03/25 | |||||||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | Biochemical | 8 | mmol/kg/d | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | El-Alfy,A., B. Larsen, and D. Schlenk | Effect of Cortisol and Urea on Flavin Monooxygenase Activity and Expression in Rainbow Trout, Oncorhynchus mykiss | Mar. Environ. Res.54(3-5): 275-278 | 2002 | 2016/03/25 | |||||||||
| 魚類 | Cyprinus carpio (Carp) | Growth | 50000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Rajyasree,M., and P. Neeraja | Protein Enrichment in Fish Cyprinus carpio on Chronic Exposure to Ambient Urea | Environ. Ecol.7(4): 922-924 | 1989 | 2016/03/25 | |||||||||
| 魚類 | Danio rerio (Zebrafish) | No Group Code | LOEC | 166 | mmol/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Lange,M., W. Gebauer, J. Markl, and R. Nagel | Comparison of Testing Acute Toxicity on Embryo of Zebrafish, Brachydanio rerio and RTG-2 Cytotoxicity as Possible Alternatives to the Acute Fish Test | Chemosphere30(11): 2087-2102 | 1995 | 2016/03/25 | ||||||||
| 魚類 | Cyprinus carpio (Carp) | Cellular Effects | 500000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Al Kahem,H.F., Z. Ahmed, and I. Alomer | A Study on the Behavioural Response and Haematological Profile of Carp, Cyprinus carpio, Exposed to Exogenous Urea | Z. Angew. Zool.80(1): 97-106 | 1994 | 2016/03/25 | |||||||||
| 魚類 | Poecilia reticulata (Guppy) | Mortality | LC50 | 4 | days | 17500000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Chouhan,M.S., and A.K. Pandey | On the Tolerannce Limits and Toxicity Symptoms of Guppy (Lebistes reticulatus)to Fertilizers: Urea and Ammonium Sulphate | Comp. Physiol. Ecol.12(2): 77-80 | 1987 | 2016/03/25 | ||||||
| 魚類 | Danio rerio (Zebrafish) | No Group Code | NOEC | 83 | mmol/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Lange,M., W. Gebauer, J. Markl, and R. Nagel | Comparison of Testing Acute Toxicity on Embryo of Zebrafish, Brachydanio rerio and RTG-2 Cytotoxicity as Possible Alternatives to the Acute Fish Test | Chemosphere30(11): 2087-2102 | 1995 | 2016/03/25 | ||||||||
| 魚類 | Poecilia reticulata (Guppy) | Mortality | LC50 | 2 | days | 22295000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Chouhan,M.S., and A.K. Pandey | On the Tolerannce Limits and Toxicity Symptoms of Guppy (Lebistes reticulatus)to Fertilizers: Urea and Ammonium Sulphate | Comp. Physiol. Ecol.12(2): 77-80 | 1987 | 2016/03/25 | ||||||
| 魚類 | Cyprinus carpio (Carp) | Biochemical | 50000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Rajyasree,M., and P. Neeraja | Protein Enrichment in Fish Cyprinus carpio on Chronic Exposure to Ambient Urea | Environ. Ecol.7(4): 922-924 | 1989 | 2016/03/25 | |||||||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | Biochemical | 8 | mmol/kg/d | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | El-Alfy,A., B. Larsen, and D. Schlenk | Effect of Cortisol and Urea on Flavin Monooxygenase Activity and Expression in Rainbow Trout, Oncorhynchus mykiss | Mar. Environ. Res.54(3-5): 275-278 | 2002 | 2016/03/25 | |||||||||
| 魚類 | Cyprinus carpio (Carp) | Biochemical | 50000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Rajyashree,M., and D.A. Perviz | Influence of Carbamide Branched Chain Aminotransferases of the Fish Cyprinus carpio | Environ. Ecol.12(1): 227-228 | 1994 | 2016/03/25 | |||||||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | Biochemical | 8 | mmol/kg/d | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | El-Alfy,A., B. Larsen, and D. Schlenk | Effect of Cortisol and Urea on Flavin Monooxygenase Activity and Expression in Rainbow Trout, Oncorhynchus mykiss | Mar. Environ. Res.54(3-5): 275-278 | 2002 | 2016/03/25 | |||||||||
| 魚類 | Danio rerio (Zebrafish) | Mortality | EC50 | 374 | mmol/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Lange,M., W. Gebauer, J. Markl, and R. Nagel | Comparison of Testing Acute Toxicity on Embryo of Zebrafish, Brachydanio rerio and RTG-2 Cytotoxicity as Possible Alternatives to the Acute Fish Test | Chemosphere30(11): 2087-2102 | 1995 | 2016/03/25 | ||||||||
| 魚類 | Poecilia reticulata (Guppy) | Mortality | LC50 | 3 | days | 18728000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Chouhan,M.S., and A.K. Pandey | On the Tolerannce Limits and Toxicity Symptoms of Guppy (Lebistes reticulatus)to Fertilizers: Urea and Ammonium Sulphate | Comp. Physiol. Ecol.12(2): 77-80 | 1987 | 2016/03/25 | ||||||
| 魚類 | Poecilia reticulata (Guppy) | Mortality | LC50 | 1 | days | 27500000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Chouhan,M.S., and A.K. Pandey | On the Tolerannce Limits and Toxicity Symptoms of Guppy (Lebistes reticulatus)to Fertilizers: Urea and Ammonium Sulphate | Comp. Physiol. Ecol.12(2): 77-80 | 1987 | 2016/03/25 | ||||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | Biochemical | 8 | mmol/kg/d | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | El-Alfy,A., B. Larsen, and D. Schlenk | Effect of Cortisol and Urea on Flavin Monooxygenase Activity and Expression in Rainbow Trout, Oncorhynchus mykiss | Mar. Environ. Res.54(3-5): 275-278 | 2002 | 2016/03/25 | |||||||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | Accumulation | 8 | mmol/kg/d | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | El-Alfy,A., B. Larsen, and D. Schlenk | Effect of Cortisol and Urea on Flavin Monooxygenase Activity and Expression in Rainbow Trout, Oncorhynchus mykiss | Mar. Environ. Res.54(3-5): 275-278 | 2002 | 2016/03/25 | |||||||||
| 魚類 | Oncorhynchus mykiss (Rainbow trout) | Biochemical | 8 | mmol/kg/d | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | El-Alfy,A., B. Larsen, and D. Schlenk | Effect of Cortisol and Urea on Flavin Monooxygenase Activity and Expression in Rainbow Trout, Oncorhynchus mykiss | Mar. Environ. Res.54(3-5): 275-278 | 2002 | 2016/03/25 | |||||||||
| 魚類 | Cyprinus carpio (Carp) | Biochemical | 50000 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Babu,C.S., K.P.O. Reddy, K. Gunasekhar, D.M. Raj, E.S. Latha, and P. Neeraja | Effect of Non-Protein Nitrogen on Nitrogenous End Products of the Fish Cyprinus carpio | Environ. Ecol.11(3): 675-678 | 1993 | 2016/03/25 | |||||||||
| 魚類 | Danio rerio (Zebrafish) | No Group Code | EC50 | 323 | mmol/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Lange,M., W. Gebauer, J. Markl, and R. Nagel | Comparison of Testing Acute Toxicity on Embryo of Zebrafish, Brachydanio rerio and RTG-2 Cytotoxicity as Possible Alternatives to the Acute Fish Test | Chemosphere30(11): 2087-2102 | 1995 | 2016/03/25 | ||||||||
| 魚類 | Leuciscus idus (Orfe) | mortality | LC50 | 48 | hours | >10000 | mg/L | × | 12 ECHA Information on Registered Substances | 2 | Juhnke, I. & Ludemann, D. | Results of the investigation of 200 chemical compounds for acute fish toxicity with the Golden Orfe test [Ergebnisse der Untersuchung von 200 chemischen Vergindungen auf akute Fischtoxizitat mit dem Goldorfentest] | Zeitschrift fuer Wasser und Abwasser Forschung | 1978 | 2016/02/26 | ||||
| 魚類 | Leuciscus idus (Orfe) | mortality | LC0 | 48 | hours | >10000 | mg/L | × | 12 ECHA Information on Registered Substances | 2 | Juhnke, I. & Ludemann, D. | Results of the investigation of 200 chemical compounds for acute fish toxicity with the Golden Orfe test [Ergebnisse der Untersuchung von 200 chemischen Vergindungen auf akute Fischtoxizitat mit dem Goldorfentest] | Zeitschrift fuer Wasser und Abwasser Forschung | 1978 | 2016/02/26 | ||||
| 魚類 | Leuciscus idus (Orfe) | mortality | LC50 | 96 | hours | >6810 | mg/L | 12 ECHA Information on Registered Substances | 2 | other company data | 1978 | 2016/02/26 | |||||||
| 魚類 | Leuciscus idus (Orfe) | LC0 | 48 | days | >10000 | mg/L | × | 11 Japan チャレンジプログラム | Juhnke, I. and Ludemann, D. | Zeitschrift fuer Wasser undAbwasser Forschung,11 | 1978 | 2016/03/12 | |||||||
| 魚類 | Leuciscus idus (Orfe) | LC0 | 48 | hours | >10000 | mg/L | × | 4 OECD SIDS (HPVC) | Juhnke, I. and Ludemann, D | Zeitschrift fuer Wasser und Abwasser Forschung | 1978 | 2016/02/25 |