化学物質有害性情報データベース 物質情報

CAS 登録番号 CAS RN® : 57136
官報公示整理番号 METI No. : 8-120
物質名 test material : 尿素 /Urea
水溶解度 water solubility : 5.4mg/L (実測値 measured)
LogKow : -2.11 (実測値 measured)
備考 remarks
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【注意事項】
* 化学物質有害性情報データベース情報更新日が2019年9月以前はRead-acrossデータでも○としていないので、毒性値の取り扱いには注意が必要である。

                       
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) Read-across * QSAR GLP 設定濃度 実測濃度 情報源 情報源による信頼性評価 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure duration value exposure duration unit toxicity value toxicity unit Read-across QSAR GLPnominal concentration measured concentrationoriginal work type original work reliability rankauthor title referenced journal publication year Information update date
藻類 Chlorella vulgaris Population IC50 5 days 5000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Przytocka-Jusiak,M. Growth and Survival of Chlorella vulgaris in high Concentrations of Nitrogen Acta Microbiol. Pol.25(3): 287-289 1976 2016/03/25
藻類 Scenedesmus sp. Scenedesmus quadricauda Toxicity threshold 192 hours >10000 mg/L 11 Japan チャレンジプログラム Bringmann, G. and Kuhn, R. Vom Wasser, 50 1978 2016/03/12
甲殻類 Ceriodaphnia dubia Physiology EC50 2 days 6573100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Warne,M.S.J., and A.D. Schifko Toxicity of Laundry Detergent Components to a Freshwater Cladoceran and Their Contribution to Detergent Toxicity Ecotoxicol. Environ. Saf.44(2): 196-206 1999 2016/03/25
甲殻類 Daphnia magna Biochemical EC50 1 hours 4070000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Janssen,C.R., E.Q. Espiritu, and G. Persoone Evaluation of the New "Enzymatic Inhibition" Criterion for Rapid Toxicity Testing with Daphnia magna In: A.Soares and P.Calow (Eds.), Progress in Standardization of Aquatic Toxicity Tests, Lewis Publ.:71-81 1993 2016/03/25
甲殻類 Daphnia magna Behavior EC50 1 days >10000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuehn Results of Toxic Action of Water Pollutants on Daphnia magna Straus Tested by an Improved Standardized Procedure Z. Wasser-Abwasser-Forsch.15(1): 1-6 1982 2016/03/25
甲殻類 Daphnia magna Physiology EC50 2 days 3910000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Janssen,C.R., E.Q. Espiritu, and G. Persoone Evaluation of the New "Enzymatic Inhibition" Criterion for Rapid Toxicity Testing with Daphnia magna In: A.Soares and P.Calow (Eds.), Progress in Standardization of Aquatic Toxicity Tests, Lewis Publ.:71-81 1993 2016/03/25
甲殻類 Daphnia magna Physiology EC50 1 days 6390000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Janssen,C.R., E.Q. Espiritu, and G. Persoone Evaluation of the New "Enzymatic Inhibition" Criterion for Rapid Toxicity Testing with Daphnia magna In: A.Soares and P.Calow (Eds.), Progress in Standardization of Aquatic Toxicity Tests, Lewis Publ.:71-81 1993 2016/03/25
甲殻類 Ceriodaphnia dubia Physiology EC50 2 days 6573100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Warne,M.S.J., and A.D. Schifko Toxicity of Laundry Detergent Components to a Freshwater Cladoceran and Their Contribution to Detergent Toxicity Ecotoxicol. Environ. Saf.44(2): 196-206 1999 2016/03/25
甲殻類 Daphnia magna Physiology LC50 1 days >10000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuhn Results of the Damaging Effect of Water Pollutants on Daphnia magna (Befunde der Schadwirkung Wassergefahrdender Stoffe Gegen Daphnia magna) TR-79-1204, Literature Research Company, Annandale, VA:26 p. 1977 2016/03/25
甲殻類 Daphnia magna EC50 24 hours >10000 mg/L 11 Japan チャレンジプログラム Bringmann, G. and Kuhn, R. Zeitschrift fuer Wasser undAbwasser Forschung, 15(1), 1982 2016/03/12
甲殻類 Daphnia magna EC50 24 hours >10000 mg/L 4 OECD SIDS (HPVC) Bringmann, G. and Kuhn, R Zeitschrift fuer Wasser und Abwasser Forschung 1982 2016/02/25
甲殻類 Daphnia magna mobility EC50 24 hours >10000 mg/L 12 ECHA Information on Registered Substances 2 publication 1982 2016/02/26
魚類 Oncorhynchus mykiss (Rainbow trout) Biochemical 8 その他others [mmol/kg/d] 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) El-Alfy,A., B. Larsen, and D. Schlenk Effect of Cortisol and Urea on Flavin Monooxygenase Activity and Expression in Rainbow Trout, Oncorhynchus mykiss Mar. Environ. Res.54(3-5): 275-278 2002 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Biochemical 8 その他others [mmol/kg/d] 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) El-Alfy,A., B. Larsen, and D. Schlenk Effect of Cortisol and Urea on Flavin Monooxygenase Activity and Expression in Rainbow Trout, Oncorhynchus mykiss Mar. Environ. Res.54(3-5): 275-278 2002 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Biochemical 8 その他others [mmol/kg/d] 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) El-Alfy,A., B. Larsen, and D. Schlenk Effect of Cortisol and Urea on Flavin Monooxygenase Activity and Expression in Rainbow Trout, Oncorhynchus mykiss Mar. Environ. Res.54(3-5): 275-278 2002 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Biochemical 8 その他others [mmol/kg/d] 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) El-Alfy,A., B. Larsen, and D. Schlenk Effect of Cortisol and Urea on Flavin Monooxygenase Activity and Expression in Rainbow Trout, Oncorhynchus mykiss Mar. Environ. Res.54(3-5): 275-278 2002 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Biochemical 8 その他others [mmol/kg/d] 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) El-Alfy,A., B. Larsen, and D. Schlenk Effect of Cortisol and Urea on Flavin Monooxygenase Activity and Expression in Rainbow Trout, Oncorhynchus mykiss Mar. Environ. Res.54(3-5): 275-278 2002 2016/03/25
魚類 Danio rerio (Zebrafish) No Group Code NOEC 83 mmol/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Lange,M., W. Gebauer, J. Markl, and R. Nagel Comparison of Testing Acute Toxicity on Embryo of Zebrafish, Brachydanio rerio and RTG-2 Cytotoxicity as Possible Alternatives to the Acute Fish Test Chemosphere30(11): 2087-2102 1995 2016/03/25
魚類 Cyprinus carpio (Carp) Biochemical 500000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Al Kahem,H.F., Z. Ahmed, and I. Alomer A Study on the Behavioural Response and Haematological Profile of Carp, Cyprinus carpio, Exposed to Exogenous Urea Z. Angew. Zool.80(1): 97-106 1994 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Accumulation 8 その他others [mmol/kg/d] 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) El-Alfy,A., B. Larsen, and D. Schlenk Effect of Cortisol and Urea on Flavin Monooxygenase Activity and Expression in Rainbow Trout, Oncorhynchus mykiss Mar. Environ. Res.54(3-5): 275-278 2002 2016/03/25
魚類 Cyprinus carpio (Carp) Biochemical 50000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Rajyasree,M., and P. Neeraja Protein Enrichment in Fish Cyprinus carpio on Chronic Exposure to Ambient Urea Environ. Ecol.7(4): 922-924 1989 2016/03/25
魚類 Cyprinus carpio (Carp) Cellular Effects 500000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Al Kahem,H.F., Z. Ahmed, and I. Alomer A Study on the Behavioural Response and Haematological Profile of Carp, Cyprinus carpio, Exposed to Exogenous Urea Z. Angew. Zool.80(1): 97-106 1994 2016/03/25
魚類 Cyprinus carpio (Carp) Biochemical 50000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Rajyashree,M., and D.A. Perviz Influence of Carbamide Branched Chain Aminotransferases of the Fish Cyprinus carpio Environ. Ecol.12(1): 227-228 1994 2016/03/25
魚類 Cyprinus carpio (Carp) Biochemical 50000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Babu,C.S., K.P.O. Reddy, K. Gunasekhar, D.M. Raj, E.S. Latha, and P. Neeraja Effect of Non-Protein Nitrogen on Nitrogenous End Products of the Fish Cyprinus carpio Environ. Ecol.11(3): 675-678 1993 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality EC50 374 mmol/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Lange,M., W. Gebauer, J. Markl, and R. Nagel Comparison of Testing Acute Toxicity on Embryo of Zebrafish, Brachydanio rerio and RTG-2 Cytotoxicity as Possible Alternatives to the Acute Fish Test Chemosphere30(11): 2087-2102 1995 2016/03/25
魚類 Danio rerio (Zebrafish) No Group Code EC50 323 mmol/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Lange,M., W. Gebauer, J. Markl, and R. Nagel Comparison of Testing Acute Toxicity on Embryo of Zebrafish, Brachydanio rerio and RTG-2 Cytotoxicity as Possible Alternatives to the Acute Fish Test Chemosphere30(11): 2087-2102 1995 2016/03/25
魚類 Poecilia reticulata (Guppy) Mortality LC50 3 days 18728000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Chouhan,M.S., and A.K. Pandey On the Tolerannce Limits and Toxicity Symptoms of Guppy (Lebistes reticulatus)to Fertilizers: Urea and Ammonium Sulphate Comp. Physiol. Ecol.12(2): 77-80 1987 2016/03/25
魚類 Poecilia reticulata (Guppy) Mortality LC50 4 days 17500000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Chouhan,M.S., and A.K. Pandey On the Tolerannce Limits and Toxicity Symptoms of Guppy (Lebistes reticulatus)to Fertilizers: Urea and Ammonium Sulphate Comp. Physiol. Ecol.12(2): 77-80 1987 2016/03/25
魚類 Poecilia reticulata (Guppy) Mortality LC50 2 days 22295000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Chouhan,M.S., and A.K. Pandey On the Tolerannce Limits and Toxicity Symptoms of Guppy (Lebistes reticulatus)to Fertilizers: Urea and Ammonium Sulphate Comp. Physiol. Ecol.12(2): 77-80 1987 2016/03/25
魚類 Poecilia reticulata (Guppy) Mortality LC50 1 days 27500000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Chouhan,M.S., and A.K. Pandey On the Tolerannce Limits and Toxicity Symptoms of Guppy (Lebistes reticulatus)to Fertilizers: Urea and Ammonium Sulphate Comp. Physiol. Ecol.12(2): 77-80 1987 2016/03/25
魚類 Danio rerio (Zebrafish) No Group Code LOEC 166 mmol/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Lange,M., W. Gebauer, J. Markl, and R. Nagel Comparison of Testing Acute Toxicity on Embryo of Zebrafish, Brachydanio rerio and RTG-2 Cytotoxicity as Possible Alternatives to the Acute Fish Test Chemosphere30(11): 2087-2102 1995 2016/03/25
魚類 Cyprinus carpio (Carp) Growth 50000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Rajyasree,M., and P. Neeraja Protein Enrichment in Fish Cyprinus carpio on Chronic Exposure to Ambient Urea Environ. Ecol.7(4): 922-924 1989 2016/03/25
魚類 Leuciscus idus (Orfe) LC0 48 days >10000 mg/L × 11 Japan チャレンジプログラム Juhnke, I. and Ludemann, D. Zeitschrift fuer Wasser undAbwasser Forschung,11 1978 2016/03/12
魚類 Leuciscus idus (Orfe) LC0 48 hours >10000 mg/L × 4 OECD SIDS (HPVC) Juhnke, I. and Ludemann, D Zeitschrift fuer Wasser und Abwasser Forschung 1978 2016/02/25
魚類 Leuciscus idus (Orfe) mortality LC50 96 hours >6810 mg/L 12 ECHA Information on Registered Substances 2 other company data 1978 2016/02/26
魚類 Leuciscus idus (Orfe) mortality LC0 48 hours >10000 mg/L × 12 ECHA Information on Registered Substances 2 Juhnke, I. & Ludemann, D. Results of the investigation of 200 chemical compounds for acute fish toxicity with the Golden Orfe test [Ergebnisse der Untersuchung von 200 chemischen Vergindungen auf akute Fischtoxizitat mit dem Goldorfentest] Zeitschrift fuer Wasser und Abwasser Forschung 1978 2016/02/26
魚類 Leuciscus idus (Orfe) mortality LC50 48 hours >10000 mg/L × 12 ECHA Information on Registered Substances 2 Juhnke, I. & Ludemann, D. Results of the investigation of 200 chemical compounds for acute fish toxicity with the Golden Orfe test [Ergebnisse der Untersuchung von 200 chemischen Vergindungen auf akute Fischtoxizitat mit dem Goldorfentest] Zeitschrift fuer Wasser und Abwasser Forschung 1978 2016/02/26