生態影響に係る有害性情報


CAS登録番号 CAS RN ® : 67-63-0
官報公示整理番号 METI No. : 2-207
物質名 test material : プロパン-2-オール /Propan-2-ol
水溶解度 water solubility : 1000000mg/L (推計値 estimated)
LogKow : 0.05 (実測値 measured)
備考 remarks
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書) / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし 4:情報が少なく評価不能
日本環境省 化学物質の環境リスク評価(生態リスク初期評価) A:試験は信頼できる B:試験は条件付きで信頼できる C:試験の信頼性は低い D:信頼性の判定不可 E:信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり Supplemental:条件付きで信頼性あり Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり:○
なし:×
情報源 情報源による
信頼性評価**
著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value
exposure
duration
unit
toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material
original work type original work
reliability rank
author title referenced journal publication year Information
update date
藻類 Chlorella sp. Population 79000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Adams,V.D., R.R. Renk, P.A. Cowan, and D.B. Porcella Naturally Occurring Organic Compounds and Algal Growth in a Eutrophic Lake Utah Center for Water Resources Reserch, Logan, UT:140 p. 1975 2016/03/25
甲殻類 Daphnia magna Physiology LC50 1 days >10000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuhn Results of the Damaging Effect of Water Pollutants on Daphnia magna (Befunde der Schadwirkung Wassergefahrdender Stoffe Gegen Daphnia magna) TR-79-1204, Literature Research Company, Annandale, VA:26 p. 1977 2016/03/25
甲殻類 Daphnia magna Physiology LC0 1 days 5000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuhn Results of the Damaging Effect of Water Pollutants on Daphnia magna (Befunde der Schadwirkung Wassergefahrdender Stoffe Gegen Daphnia magna) TR-79-1204, Literature Research Company, Annandale, VA:26 p. 1977 2016/03/25
甲殻類 Daphnia magna Physiology EC50 1 days 114 mM 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Lilius,H., B. Isomaa, and T. Holmstrom A Comparison of the Toxicity of 50 Reference Chemicals to Freshly Isolated Rainbow Trout Hepatocytes and Daphnia magna Aquat. Toxicol.30:47-60 1994 2016/03/25
甲殻類 Daphnia magna Physiology EC50 1 days 159000 μmol/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Calleja,M.C., G. Persoone, and P. Geladi Comparative Acute Toxicity of the First 50 Multicentre Evaluation of In Vitro Cytotoxicity Chemicals to Aquatic Non-vertebrates Arch. Environ. Contam. Toxicol.26(1): 69-78 1994 2016/03/25
甲殻類 Daphnia magna Behavior EC50 1 days 9714000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuehn Results of Toxic Action of Water Pollutants on Daphnia magna Straus Tested by an Improved Standardized Procedure Z. Wasser-Abwasser-Forsch.15(1): 1-6 1982 2016/03/25
甲殻類 Daphnia magna Behavior EC0 1 days 5102000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuehn Results of Toxic Action of Water Pollutants on Daphnia magna Straus Tested by an Improved Standardized Procedure Z. Wasser-Abwasser-Forsch.15(1): 1-6 1982 2016/03/25
甲殻類 Daphnia magna Behavior EC100 1 days 10000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuehn Results of Toxic Action of Water Pollutants on Daphnia magna Straus Tested by an Improved Standardized Procedure Z. Wasser-Abwasser-Forsch.15(1): 1-6 1982 2016/03/25
甲殻類 Daphnia magna Reproduction EC50 384 hours 3227.55 mg/L 9 ECETOC Aquatic Toxicity, EAT De Wolf ea 88 2016/02/08
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 1 hours 11830000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Mattson,V.R., J.W. Arthur, and C.T. Walbridge Acute Toxicity of Selected Organic Compounds to Fathead Minnows EPA-600/3-76-097, U.S.EPA, Duluth, MN:12 p. 1976 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical 18 days 100000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Andersen,L., K. Kinnberg, H. Holbech, B. Korsgaard, and P. Bjerregaard Evaluation of a 40 day Assay for Testing Endocrine Disrupters: Effects of an Anti-Estrogen and an Aromatase Inhibitor on Sex Ratio and Vitellogenin Concentrations in Juvenile Zebrafish (Danio rerio) Fish Physiol. Biochem.30(3-4): 257-266 2004 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality 40 days 100000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Andersen,L., K. Kinnberg, H. Holbech, B. Korsgaard, and P. Bjerregaard Evaluation of a 40 day Assay for Testing Endocrine Disrupters: Effects of an Anti-Estrogen and an Aromatase Inhibitor on Sex Ratio and Vitellogenin Concentrations in Juvenile Zebrafish (Danio rerio) Fish Physiol. Biochem.30(3-4): 257-266 2004 2016/03/25
魚類 Danio rerio (Zebrafish) Growth 7 days 1000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Andersen,L., R. Goto-Kazeto, J.M. Trant, J.P. Nash, B. Korsgaard, and P. Bjerregaard Short-Term Exposure to Low Concentrations of the Synthetic Androgen Methyltestosterone Affects Vitellogenin and Steroid Levels in Adult male Zebrafish (Danio rerio) Aquat. Toxicol.76(3-4): 343-352 2006 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 10400000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Brooke,L.T., D.J. Call, D.L. Geiger, and C.E. Northcott Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales promelas), Vol. 1 Center for Lake Superior Environmental Studies, University of Wisconsin-Superior, Superior, WI:414 p. 1984 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 7 days 1000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Andersen,L., R. Goto-Kazeto, J.M. Trant, J.P. Nash, B. Korsgaard, and P. Bjerregaard Short-Term Exposure to Low Concentrations of the Synthetic Androgen Methyltestosterone Affects Vitellogenin and Steroid Levels in Adult male Zebrafish (Danio rerio) Aquat. Toxicol.76(3-4): 343-352 2006 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Accumulation 4800000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Call,D.J., L.T. Brooke, and N. Ahmad Estimates of "No Effect" Concentrations of Selected Pesticides in Freshwater Organisms Fourth Quarterly Prog.Rep.to EPA, EPA Coop.Agreement No.CR 806864030, Univ.of Wisconsin, Superior, WI:84 p. 1981 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 7 days 1000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Andersen,L., R. Goto-Kazeto, J.M. Trant, J.P. Nash, B. Korsgaard, and P. Bjerregaard Short-Term Exposure to Low Concentrations of the Synthetic Androgen Methyltestosterone Affects Vitellogenin and Steroid Levels in Adult male Zebrafish (Danio rerio) Aquat. Toxicol.76(3-4): 343-352 2006 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 7 days 1000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Andersen,L., R. Goto-Kazeto, J.M. Trant, J.P. Nash, B. Korsgaard, and P. Bjerregaard Short-Term Exposure to Low Concentrations of the Synthetic Androgen Methyltestosterone Affects Vitellogenin and Steroid Levels in Adult male Zebrafish (Danio rerio) Aquat. Toxicol.76(3-4): 343-352 2006 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 7 days 1000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Andersen,L., R. Goto-Kazeto, J.M. Trant, J.P. Nash, B. Korsgaard, and P. Bjerregaard Short-Term Exposure to Low Concentrations of the Synthetic Androgen Methyltestosterone Affects Vitellogenin and Steroid Levels in Adult male Zebrafish (Danio rerio) Aquat. Toxicol.76(3-4): 343-352 2006 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 11130000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Mattson,V.R., J.W. Arthur, and C.T. Walbridge Acute Toxicity of Selected Organic Compounds to Fathead Minnows EPA-600/3-76-097, U.S.EPA, Duluth, MN:12 p. 1976 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 1 days 11160000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Mattson,V.R., J.W. Arthur, and C.T. Walbridge Acute Toxicity of Selected Organic Compounds to Fathead Minnows EPA-600/3-76-097, U.S.EPA, Duluth, MN:12 p. 1976 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 2 days 11130000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Mattson,V.R., J.W. Arthur, and C.T. Walbridge Acute Toxicity of Selected Organic Compounds to Fathead Minnows EPA-600/3-76-097, U.S.EPA, Duluth, MN:12 p. 1976 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Behavior EC50 1 days 9380000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Call,D.J., L.T. Brooke, and N. Ahmad Estimates of "No Effect" Concentrations of Selected Pesticides in Freshwater Organisms Fourth Quarterly Prog.Rep.to EPA, EPA Coop.Agreement No.CR 806864030, Univ.of Wisconsin, Superior, WI:84 p. 1981 2016/03/25
魚類 Carassius auratus (Goldfish) Mortality LC50 1 days >5000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bridie,A.L., C.J.M. Wolff, and M. Winter The Acute Toxicity of Some Petrochemicals to Goldfish Water Res.13(7): 623-626 1979 2016/03/25
魚類 Danio rerio (Zebrafish) Growth 100000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Andersen,L., K. Kinnberg, H. Holbech, B. Korsgaard, and P. Bjerregaard Evaluation of a 40 day Assay for Testing Endocrine Disrupters: Effects of an Anti-Estrogen and an Aromatase Inhibitor on Sex Ratio and Vitellogenin Concentrations in Juvenile Zebrafish (Danio rerio) Fish Physiol. Biochem.30(3-4): 257-266 2004 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Behavior EC50 2 days 10000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Call,D.J., L.T. Brooke, and N. Ahmad Estimates of "No Effect" Concentrations of Selected Pesticides in Freshwater Organisms Fourth Quarterly Prog.Rep.to EPA, EPA Coop.Agreement No.CR 806864030, Univ.of Wisconsin, Superior, WI:84 p. 1981 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality LC0 4 days >10000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Buzzell,J.C.,Jr., R.H.F. Young, and D.W. Ryckman Behavior of Organic Chemicals in the Aquatic Environment. Part II. - Behavior in Dilute Systems Environ.Sanitary Engineering Labs., Washington University, St.Louis, MO:81 p. 1968 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 1 days 10600000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Call,D.J., L.T. Brooke, and N. Ahmad Estimates of "No Effect" Concentrations of Selected Pesticides in Freshwater Organisms Fourth Quarterly Prog.Rep.to EPA, EPA Coop.Agreement No.CR 806864030, Univ.of Wisconsin, Superior, WI:84 p. 1981 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 7 days 1000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Andersen,L., R. Goto-Kazeto, J.M. Trant, J.P. Nash, B. Korsgaard, and P. Bjerregaard Short-Term Exposure to Low Concentrations of the Synthetic Androgen Methyltestosterone Affects Vitellogenin and Steroid Levels in Adult male Zebrafish (Danio rerio) Aquat. Toxicol.76(3-4): 343-352 2006 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 7 days 1000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Andersen,L., R. Goto-Kazeto, J.M. Trant, J.P. Nash, B. Korsgaard, and P. Bjerregaard Short-Term Exposure to Low Concentrations of the Synthetic Androgen Methyltestosterone Affects Vitellogenin and Steroid Levels in Adult male Zebrafish (Danio rerio) Aquat. Toxicol.76(3-4): 343-352 2006 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 2 days >1400000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Wolverton,B.C., D.D. Harrison, and R.C. Voight Toxicity of CS-2 Decontamination Products Tech.Report AFATL-TR-70-68, Air Force Armament Laboratory, Eglin Air Force Base, FL:13 p. 1970 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 3 days 11130000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Mattson,V.R., J.W. Arthur, and C.T. Walbridge Acute Toxicity of Selected Organic Compounds to Fathead Minnows EPA-600/3-76-097, U.S.EPA, Duluth, MN:12 p. 1976 2016/03/25
魚類 Danio rerio (Zebrafish) Population 40 days 100000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Andersen,L., K. Kinnberg, H. Holbech, B. Korsgaard, and P. Bjerregaard Evaluation of a 40 day Assay for Testing Endocrine Disrupters: Effects of an Anti-Estrogen and an Aromatase Inhibitor on Sex Ratio and Vitellogenin Concentrations in Juvenile Zebrafish (Danio rerio) Fish Physiol. Biochem.30(3-4): 257-266 2004 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 6550000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Brooke,L.T., D.J. Call, D.L. Geiger, and C.E. Northcott Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales promelas), Vol. 1 Center for Lake Superior Environmental Studies, University of Wisconsin-Superior, Superior, WI:414 p. 1984 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 4 days >1400000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Wolverton,B.C., D.D. Harrison, and R.C. Voight Toxicity of CS-2 Decontamination Products Tech.Report AFATL-TR-70-68, Air Force Armament Laboratory, Eglin Air Force Base, FL:13 p. 1970 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 3 days >1400000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Wolverton,B.C., D.D. Harrison, and R.C. Voight Toxicity of CS-2 Decontamination Products Tech.Report AFATL-TR-70-68, Air Force Armament Laboratory, Eglin Air Force Base, FL:13 p. 1970 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 1 days >1400000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Wolverton,B.C., D.D. Harrison, and R.C. Voight Toxicity of CS-2 Decontamination Products Tech.Report AFATL-TR-70-68, Air Force Armament Laboratory, Eglin Air Force Base, FL:13 p. 1970 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 2 days 10400000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Call,D.J., L.T. Brooke, and N. Ahmad Estimates of "No Effect" Concentrations of Selected Pesticides in Freshwater Organisms Fourth Quarterly Prog.Rep.to EPA, EPA Coop.Agreement No.CR 806864030, Univ.of Wisconsin, Superior, WI:84 p. 1981 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 9640000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Brooke,L.T., D.J. Call, D.L. Geiger, and C.E. Northcott Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales promelas), Vol. 1 Center for Lake Superior Environmental Studies, University of Wisconsin-Superior, Superior, WI:414 p. 1984 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours >100 mg/L 3 USEPA Pesticide Ecotoxicity Database J. McCann 1973 2016/02/02
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours 1.62 mg/L 3 USEPA Pesticide Ecotoxicity Database J. McCann 2004 2016/02/02
魚類 Lepomis macrochirus (Bluegill) LC50 96 hours 1.91 mg/L 3 USEPA Pesticide Ecotoxicity Database J. McCann 2004 2016/02/02
魚類 Pimephales promelas (Fathead minnow) Lethal EC50 96 hours 10400 mg/L 9 ECETOC Aquatic Toxicity, EAT Veith ea 83 2016/02/08
魚類 Poecilia reticulata (Guppy) Mortality LC50 96 hours 8690 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Raevsky, O.A., and Dearden, J.C. Creation of predictive models of aquatic toxicity of environmental pollutants with different mechanisms of action on the basis of molecular similarity and hybot descriptors. 2004 2016/02/08
魚類 Leuciscus idus (Orfe) Mortality LC50 96 hours 8890 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Furusjö, E., Andersson, M., Rahmberg, M., Svenson, A. Estimating environmentally important properties of chemicals from the chemical structure 2003 2016/02/08
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 96 hours 8890 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Russom, C.L., Bradbury, S.P., Broderius, S.J., Drummond, R.A. and Hammermeister, D.E. PREDICTING MODES OF TOXIC ACTION FROM CHEMICAL STRUCTURE: ACUTE TOXICITY IN THE FATHEAD MINNOW (PIMEPHALES PROMELAS) 1997 2016/02/08
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours 13000 mg/L 3 USEPA Pesticide Ecotoxicity Database Mayer & Ellersieck 1986 2016/02/02
魚類 Carassius auratus (Goldfish) Mortality LC50 24 hours 7390 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Lipnick, R.L., K.R. Watson, and A.K.Strausz A QSAR Study of the Acute Toxicity of Some Industrial Organic Chemicals to Goldfish. Narcosis, Electrophile and Proelectrophile Mechanisms. 1987 2016/02/08