生態影響に係る有害性情報

CAS登録番号 CAS RN ® ： 75-37-6
官報公示整理番号　METI No. ： 2-86
物質名 test material ：１，１－ジフルオロエタン　／1,1-Difluoroethane
水溶解度 water solubility ： 3200mg/L (推計値 estimated)
LogKow ： 0.75 (実測値 measured)
備考 remarks ：
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書） / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし　4:情報が少なく評価不能
日本環境省　化学物質の環境リスク評価（生態リスク初期評価） A：試験は信頼できる　B：試験は条件付きで信頼できる　C：試験の信頼性は低い　D：信頼性の判定不可　E：信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり　Supplemental:条件付きで信頼性あり　Invalid:信頼性なし

生物種	学名	影響内容	エンドポイント	暴露期間(値)	暴露期間(単位)	毒性値	毒性値(単位)	毒性値(単位)種別				試験中の被験物質濃度測定あり：○ なし：×	情報源	情報源による信頼性評価**	著者	タイトル	記載誌	発行年	情報更新日
subject type	scientific name	effect	endpoint	exposure duration value	exposure duration unit	toxicity value	toxicity unit	toxicity unit type	Read-across*	QSAR	GLP	measurement of the test material	original work type	original work reliability rank	author	title	referenced journal	publication year	Information update date
藻類	Algae		EC50	96	hours	419	mg/L		×	○	×		19 その他	Estimated value based on accepted model	Meylan, W. M. and P. H. Howard	User’s Guide for the ECOSAR Class Program	Version 0.993 (Mar 99), prepared for J. Vincent Nabholz and Gordon Cas, U.S.Environmental Protection Agency, Office of Pollution Prevention and Toxics, Washington, DC, prepared by Syracuse Research Corp., Environmental Science Center, Syracuse, NY 132 10		2021/04/09
藻類	Algae		EC50	96	hours	91	mg/L		×	○	×		19 その他	Estimated value based on accepted model	Meylan, W. M. and P. H. Howard	User’s Guide for the ECOSAR Class Program	Version 0.993 (Mar 99), prepared for J. Vincent Nabholz and Gordon Cas, U.S.Environmental Protection Agency, Office of Pollution Prevention and Toxics, Washington, DC, prepared by Syracuse Research Corp., Environmental Science Center, Syracuse, NY 132 10		2021/04/09
甲殻類	Daphnia magna	mobility	EC50	48	hours	980	mg/L				○		12 ECHA Information on Registered Substances	4	secondary source			1999	2017/02/11
甲殻類	Daphnia magna	immobility	EC50	48	hours	980	mg/L				○		4 OECD SIDS (HPVC)	2	Stewart KM and Thompson RS	ICI Group Environmental Laboratory Report No.BL3908/B, ICI, UK	cited in Berends, A. G., C. G. de Rooij, S. Shin-ya, and R. S. Thompson (1999). Biodegradation and ecotoxicity of HFCs and HCFCs. Arch. Environ. Contam. Toxicol., 36(2):146 - 151	1991	2017/02/21
甲殻類	Daphnia magna	mobility	EC50	48	hours	980	mg/L						12 ECHA Information on Registered Substances			secondary source			2021/03/02
甲殻類	Daphnid		EC50	48	hours	150	mg/L		×	○	×		19 その他	Estimated value based on accepted model	Meylan, W. M. and P. H. Howard	User’s Guide for the ECOSAR Class Program	Version 0.993 (Mar 99), prepared for J. Vincent Nabholz and Gordon Cas, U.S.Environmental Protection Agency, Office of Pollution Prevention and Toxics, Washington, DC, prepared by Syracuse Research Corp., Environmental Science Center, Syracuse, NY 132 10		2021/04/09
甲殻類	Daphnid		EC50	48	hours	720	mg/L		×	○	×		19 その他	Estimated value based on accepted model	Meylan, W. M. and P. H. Howard	User’s Guide for the ECOSAR Class Program	Version 0.993 (Mar 99), prepared for J. Vincent Nabholz and Gordon Cas, U.S.Environmental Protection Agency, Office of Pollution Prevention and Toxics, Washington, DC, prepared by Syracuse Research Corp., Environmental Science Center, Syracuse, NY 132 10		2021/04/09
魚類	Oncorhynchus mykiss (Rainbow trout)	mortality	LC50	96	hours	450	mg/L				○		12 ECHA Information on Registered Substances	4	secondary source			1999	2017/02/11
魚類	Oncorhynchus mykiss (Rainbow trout)	mortality	LC50	96	hours	450	mg/L				○		4 OECD SIDS (HPVC)	2	Thompson RS	ICI Group Environmental Laboratory Report No. BL4035/B, ICI,UK	(cited in Berends AG, de Rooij CG, Shin-ya S, and Thompson RS (1999). Biodegradation and ecotoxicity of HFCs and HCFCs. Arch. Environ. Contam. Toxicol., 36(2):146 - 151).	1991	2017/02/21
魚類	Fish	Mortality	LC50	96	hours	145	mg/L		×	○	×		19 その他	Estimated value based on accepted model	Meylan, W. M. and P. H. Howard	User’s Guide for the ECOSAR Class Program	Version 0.993 (Mar 99), prepared for J. Vincent Nabholz and Gordon Cas, U.S.Environmental Protection Agency, Office of Pollution Prevention and Toxics, Washington, DC, prepared by Syracuse Research Corp., Environmental Science Center, Syracuse, NY 132 10		2021/04/09
魚類	Fish	Mortality	LC50	96	hours	733	mg/L		×	○	×		19 その他	Estimated value based on accepted model	Meylan, W. M. and P. H. Howard	User’s Guide for the ECOSAR Class Program	Version 0.993 (Mar 99), prepared for J. Vincent Nabholz and Gordon Cas, U.S.Environmental Protection Agency, Office of Pollution Prevention and Toxics, Washington, DC, prepared by Syracuse Research Corp., Environmental Science Center, Syracuse, NY 132 10		2021/04/09