生態影響に係る有害性情報


CAS登録番号 CAS RN ® : 75-56-9
官報公示整理番号 METI No. : 2-219
物質名 test material : 2-メチルオキシラン /2-Methyloxirane
水溶解度 water solubility : 590000mg/L (推計値 estimated)
LogKow : 0.03 (実測値 measured)
備考 remarks
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書) / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし 4:情報が少なく評価不能
日本環境省 化学物質の環境リスク評価(生態リスク初期評価) A:試験は信頼できる B:試験は条件付きで信頼できる C:試験の信頼性は低い D:信頼性の判定不可 E:信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり Supplemental:条件付きで信頼性あり Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり:○
なし:×
情報源 情報源による
信頼性評価**
著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value
exposure
duration
unit
toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material
original work type original work
reliability rank
author title referenced journal publication year Information
update date
藻類 Pseudokirchneriella subcapitata Population NOEL 4 days 860 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly: Environmental Effects Database (EEDB)) Environmental Fate and Effects Division, U.S.EPA, Washington, D.C.: 1992 2016/03/25
藻類 Pseudokirchneriella subcapitata Population EC50 4 days >860 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly: Environmental Effects Database (EEDB)) Environmental Fate and Effects Division, U.S.EPA, Washington, D.C.: 1992 2016/03/25
藻類 Pseudokirchneriella subcapitata EC50 96 hours >0.86 mg/L 3 USEPA Pesticide Ecotoxicity Database R. Sternberg 2011 2016/02/02
藻類 Pseudokirchneriella subcapitata EC50 96 hours >0.86 ppm 3 USEPA Pesticide Ecotoxicity Database R. Sternberg 2011 2018/03/22
藻類 Pseudokirchneriella subcapitata NOEL 96 hours >0.86 mg/L 3 USEPA Pesticide Ecotoxicity Database R. Sternberg 2011 2016/02/02
藻類 Pseudokirchneriella subcapitata NOEL 96 hours 0.86 ppm 3 USEPA Pesticide Ecotoxicity Database R. Sternberg 2011 2018/03/22
魚類 Lepomis macrochirus (Bluegill) Mortality 1 days 240000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Crews,R.C. Effects of Propylene Oxide on Selected Species of Fishes Tech.Rep.AFATL-TR-74-183, Environics Office, Air Force Armament Lab., Eglin Air Force Base, FL:13 p. 1974 2016/03/25
魚類 Carassius auratus (Goldfish) Mortality LC50 1 days 170000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bridie,A.L., C.J.M. Wolff, and M. Winter The Acute Toxicity of Some Petrochemicals to Goldfish Water Res.13(7): 623-626 1979 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 4 days 215000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Crews,R.C. Effects of Propylene Oxide on Selected Species of Fishes Tech.Rep.AFATL-TR-74-183, Environics Office, Air Force Armament Lab., Eglin Air Force Base, FL:13 p. 1974 2016/03/25
魚類 Carassius auratus (Goldfish) Lethal EC50 24 hours 170 mg/L 9 ECETOC Aquatic Toxicity, EAT Bridie ea 79 2016/02/08
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours 52 mg/L 7 EU Risk Assessment Report (EUリスク評価書) Shell Research Propylene oxide: acute toxicity (Salmo gairdneri, Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient. Group Research report SBGR.85.250, Shell Research Ltd, Sittingbourne Research Centre, Sittingbourne, UK. 1986 2016/02/22
魚類 Lepomis macrochirus (Bluegill) LC100 24 hours 240 mg/L 7 EU Risk Assessment Report (EUリスク評価書) Crews RC Effects of propylene oxide on selected species of fishes. Eglin Air Force Base, Florida, US Air Force Armament Center. NTIS/AD/A-003637. 1974 2016/02/22
魚類 Carassius auratus (Goldfish) LC50 24 hours 170 mg/L 7 EU Risk Assessment Report (EUリスク評価書) Bridié AL, Wolff CJM and Winter M The acute toxicity of some petrochemicals to goldfish. Water Research, 13 1979 2016/02/22
魚類 Oncorhynchus mykiss (Rainbow trout) LC100 72 hours 100 mg/L 7 EU Risk Assessment Report (EUリスク評価書) Shell Research Propylene oxide: acute toxicity (Salmo gairdneri, Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient. Group Research report SBGR.85.250, Shell Research Ltd, Sittingbourne Research Centre, Sittingbourne, UK. 1986 2016/02/22
魚類 Lepomis macrochirus (Bluegill) LC50 96 hours 215 mg/L 7 EU Risk Assessment Report (EUリスク評価書) Crews RC Effects of propylene oxide on selected species of fishes. Eglin Air Force Base, Florida, US Air Force Armament Center. NTIS/AD/A-003637. 1974 2016/02/22
魚類 Carassius auratus (Goldfish) Mortality LC50 24 hours 171 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Lipnick, R.L., K.R. Watson, and A.K.Strausz A QSAR Study of the Acute Toxicity of Some Industrial Organic Chemicals to Goldfish. Narcosis, Electrophile and Proelectrophile Mechanisms. 1987 2016/02/08
魚類 Poecilia reticulata (Guppy) Mortality LC50 96 hours 31.9 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Raevsky, O.A., and Dearden, J.C. Creation of predictive models of aquatic toxicity of environmental pollutants with different mechanisms of action on the basis of molecular similarity and hybot descriptors. 2004 2016/02/08
魚類 Lepomis macrochirus (Bluegill) NOEC 96 hours 150 mg/L 7 EU Risk Assessment Report (EUリスク評価書) Crews RC Effects of propylene oxide on selected species of fishes. Eglin Air Force Base, Florida, US Air Force Armament Center. NTIS/AD/A-003637. 1974 2016/02/22
魚類 Oncorhynchus mykiss (Rainbow trout) NOEC 96 hours 20 mg/L 7 EU Risk Assessment Report (EUリスク評価書) Shell Research Propylene oxide: acute toxicity (Salmo gairdneri, Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient. Group Research report SBGR.85.250, Shell Research Ltd, Sittingbourne Research Centre, Sittingbourne, UK. 1986 2016/02/22
魚類 Poecilia reticulata (Guppy) LC50 14 days 31.9 mg/L 7 EU Risk Assessment Report (EUリスク評価書) Deneer JW, Sinnige TL, Seinen W, and Hermens JLM Quantitative Structure-Activity Relationship for the Acute Toxicity of Some Epoxy Compounds to the Guppy. Aquatic Toxicology, 13 1988 2016/02/22