生態影響に係る有害性情報


CAS登録番号 CAS RN ® : 75-65-0
官報公示整理番号 METI No. : 2-3049
物質名 test material : 2-メチルプロパン-2-オール /2-Methylpropan-2-ol
水溶解度 water solubility : 1000000mg/L (推計値 estimated)
LogKow : 0.35 (実測値 measured)
備考 remarks
Excelファイルダウンロード

【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書) / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし 4:情報が少なく評価不能
日本環境省 化学物質の環境リスク評価(生態リスク初期評価) A:試験は信頼できる B:試験は条件付きで信頼できる C:試験の信頼性は低い D:信頼性の判定不可 E:信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり Supplemental:条件付きで信頼性あり Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり:○
なし:×
情報源 情報源による
信頼性評価**
著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value
exposure
duration
unit
toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material
original work type original work
reliability rank
author title referenced journal publication year Information
update date
藻類 Scenedesmus subspicatus Cellular Effects EC3 7 days 1580000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Trenel,J., and R. Kuhn Bewertung Wassergefahrdender Stoffe im Hinblick auf Lagerung, Umschlag und Transport Umweltforschungsplan des Bundesministers des Innern: 1982 2016/03/25
藻類 Scenedesmus subspicatus Cellular Effects EC3 7 days 6100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Trenel,J., and R. Kuhn Bewertung Wassergefahrdender Stoffe im Hinblick auf Lagerung, Umschlag und Transport Umweltforschungsplan des Bundesministers des Innern: 1982 2016/03/25
甲殻類 Daphnia magna Behavior EC50 1 days 5050000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Trenel,J., and R. Kuhn Bewertung Wassergefahrdender Stoffe im Hinblick auf Lagerung, Umschlag und Transport Umweltforschungsplan des Bundesministers des Innern: 1982 2016/03/25
甲殻類 Daphnia magna Physiology EC50 2 days 5504000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., M. Pattard, K.D. Pernak, and A. Winter Results of the Harmful Effects of Selected Water Pollutants (Anilines, Phenols, Aliphatic Compounds) to Daphnia magna Water Res.23(4): 495-499 1989 2016/03/25
甲殻類 Daphnia magna Physiology EC50 1 days 5504000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., M. Pattard, K.D. Pernak, and A. Winter Results of the Harmful Effects of Selected Water Pollutants (Anilines, Phenols, Aliphatic Compounds) to Daphnia magna Water Res.23(4): 495-499 1989 2016/03/25
甲殻類 Daphnia magna Intoxication ET50 24 hours 5490 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Urrestarazu Ramos, E. Aquatic toxicity of polar narcotic pollutants/ Mechanism, modeling and environmental effect assessment (PhD Thesis) 1998 2016/02/08
魚類 Cyprinus carpio (Carp) Cellular Effects 0.1 ml/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Gimeno,S., H. Komen, S. Jobling, J. Sumpter, and T. Bowmer Demasculinisation of Sexually Mature Male Common Carp, Cyprinus carpio, Exposed to 4-tert-Pentylphenol During Spermatogenesis Aquat. Toxicol.43(2-3): 93-109 1998 2016/03/25
魚類 Carassius auratus (Goldfish) Mortality LC50 1 days >5000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bridie,A.L., C.J.M. Wolff, and M. Winter The Acute Toxicity of Some Petrochemicals to Goldfish Water Res.13(7): 623-626 1979 2016/03/25
魚類 Cyprinus carpio (Carp) Growth 0.1 ml/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Gimeno,S., H. Komen, S. Jobling, J. Sumpter, and T. Bowmer Demasculinisation of Sexually Mature Male Common Carp, Cyprinus carpio, Exposed to 4-tert-Pentylphenol During Spermatogenesis Aquat. Toxicol.43(2-3): 93-109 1998 2016/03/25
魚類 Cyprinus carpio (Carp) Growth 0.1 ml/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Gimeno,S., H. Komen, S. Jobling, J. Sumpter, and T. Bowmer Demasculinisation of Sexually Mature Male Common Carp, Cyprinus carpio, Exposed to 4-tert-Pentylphenol During Spermatogenesis Aquat. Toxicol.43(2-3): 93-109 1998 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 6410000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Geiger,D.L., S.H. Poirier, L.T. Brooke, and D.J. Call Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales promelas) Volume III Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI:328 p. 1986 2016/03/25
魚類 Cyprinus carpio (Carp) Biochemical 0.1 ml/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Gimeno,S., H. Komen, S. Jobling, J. Sumpter, and T. Bowmer Demasculinisation of Sexually Mature Male Common Carp, Cyprinus carpio, Exposed to 4-tert-Pentylphenol During Spermatogenesis Aquat. Toxicol.43(2-3): 93-109 1998 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical 42 days <100000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bogers,R., E. Mutsaerds, J. Druke, D.F. De Roode, A.J. Murk, B. Van der Burg, and J. Legler Estrogenic Endpoints in Fish Early Life-Stage Tests: Luciferase and Vitellogenin Induction in Estrogen-Responsive Transgenic Zebrafish Environ. Toxicol. Chem.25(1): 241-247 2006 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality LC0 4 days >180000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Buzzell,J.C.,Jr., R.H.F. Young, and D.W. Ryckman Behavior of Organic Chemicals in the Aquatic Environment. Part II. - Behavior in Dilute Systems Environ.Sanitary Engineering Labs., Washington University, St.Louis, MO:81 p. 1968 2016/03/25
魚類 Carassius auratus (Goldfish) Mortality LC50 24 hours 3550 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Lipnick, R.L., K.R. Watson, and A.K.Strausz A QSAR Study of the Acute Toxicity of Some Industrial Organic Chemicals to Goldfish. Narcosis, Electrophile and Proelectrophile Mechanisms. 1987 2016/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 48 hours 5490 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) - Biodegradation and Bioaccumulation Data of Existing Chemicals Based on the CSCL Japan 1992 2016/02/08
魚類 Poecilia reticulata (Guppy) Mortality LC50 96 hours 3550 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Raevsky, O.A., and Dearden, J.C. Creation of predictive models of aquatic toxicity of environmental pollutants with different mechanisms of action on the basis of molecular similarity and hybot descriptors. 2004 2016/02/08
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 96 hours 6460 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Russom, C.L., Bradbury, S.P., Broderius, S.J., Drummond, R.A. and Hammermeister, D.E. PREDICTING MODES OF TOXIC ACTION FROM CHEMICAL STRUCTURE: ACUTE TOXICITY IN THE FATHEAD MINNOW (PIMEPHALES PROMELAS) 1997 2016/02/08