生態影響に係る有害性情報


CAS登録番号 CAS RN ® ： 7550-45-0
官報公示整理番号　METI No. ： 1-262
物質名 test material ： 四塩化チタニウム　／Titanium tetrachloride
水溶解度 water solubility ： 2741mg/L (推計値 estimated)
LogKow ： 1.47 (推計値 estimated)
備考 remarks ：
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書） / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし　4:情報が少なく評価不能
日本環境省　化学物質の環境リスク評価（生態リスク初期評価） A：試験は信頼できる　B：試験は条件付きで信頼できる　C：試験の信頼性は低い　D：信頼性の判定不可　E：信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり　Supplemental:条件付きで信頼性あり　Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり：○
なし：×		 情報源 情報源による
信頼性評価**		 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value		 exposure
duration
unit		 toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material		 original work type original work
reliability rank		 author title referenced journal publication year Information
update date
藻類 Desmodesmus subspicatus growth rate EL50 72 hours 0.55 mmol/L 12 ECHA Information on Registered Substances 3 Hund-Rinke K, Simon M Ecotoxic Effect of Photocatalytic Active Nanoparticles (TiO2) on Algae and Daphnids PMID: 16910119, Environ Sci & Pollut Res 2006 2017/01/23
藻類 Pseudokirchneriella subcapitata growth rate EL50 72 hours 61 mg/L 12 ECHA Information on Registered Substances 3 study report 2006 2017/01/23
藻類 Desmodesmus subspicatus growth rate EL50 72 hours 44 mg/L 12 ECHA Information on Registered Substances 3 Hund-Rinke K, Simon M Ecotoxic Effect of Photocatalytic Active Nanoparticles (TiO2) on Algae and Daphnids PMID: 16910119, Environ Sci & Pollut Res 2006 2017/01/23
藻類 Desmodesmus subspicatus growth rate EL50 72 hours 32 mg/L 12 ECHA Information on Registered Substances 3 Hund-Rinke K, Simon M Ecotoxic Effect of Photocatalytic Active Nanoparticles (TiO2) on Algae and Daphnids PMID: 16910119, Environ Sci & Pollut Res 2006 2017/01/23
藻類 Pseudokirchneriella subcapitata cell number EL50 72 hours 16 mg/L 12 ECHA Information on Registered Substances 3 study report 2006 2017/01/23
藻類 Desmodesmus subspicatus growth rate EC50 72 hours 0.4 mmol/L 12 ECHA Information on Registered Substances 3 Hund-Rinke K, Simon M Ecotoxic Effect of Photocatalytic Active Nanoparticles (TiO2) on Algae and Daphnids PMID: 16910119, Environ Sci & Pollut Res 2006 2017/01/23
藻類 Pseudokirchneriella subcapitata growth rate EL50 72 hours 0.763 mmol/L 12 ECHA Information on Registered Substances 3 study report 2006 2017/01/23
藻類 Pseudokirchneriella subcapitata growth rate EL10 72 hours 12.7 mg/L 12 ECHA Information on Registered Substances 3 study report 2006 2017/01/23
藻類 Pseudokirchneriella subcapitata growth rate NOELR 72 hours >1 mg/L 12 ECHA Information on Registered Substances 3 study report 2006 2017/01/23
藻類 Pseudokirchneriella subcapitata cell number EL10 72 hours 4.6 mg/L 12 ECHA Information on Registered Substances 3 study report 2006 2017/01/23
藻類 Desmodesmus subspicatus growth rate EL10 72 hours 11.3 mg/L 12 ECHA Information on Registered Substances 3 Hund-Rinke K, Simon M Ecotoxic Effect of Photocatalytic Active Nanoparticles (TiO2) on Algae and Daphnids PMID: 16910119, Environ Sci & Pollut Res 2006 2017/01/23
藻類 Pseudokirchneriella subcapitata cell number NOELR 72 hours >1 mg/L 12 ECHA Information on Registered Substances 3 study report 2006 2017/01/23
藻類 Desmodesmus subspicatus growth rate EC10 72 hours 11.7 mg/L 12 ECHA Information on Registered Substances 3 Hund-Rinke K, Simon M Ecotoxic Effect of Photocatalytic Active Nanoparticles (TiO2) on Algae and Daphnids PMID: 16910119, Environ Sci & Pollut Res 2006 2017/01/23
甲殻類 Daphnia magna EC50 48 hours >1000 mg/L ○ 12 ECHA Information on Registered Substances 2 publication 1993 2017/01/23
甲殻類 Daphnia magna EC50 48 hours >1000 mg/L ○ 12 ECHA Information on Registered Substances 2 publication 1993 2017/01/23
甲殻類 Daphnia magna mobility LL50 48 hours >100 mg/L 12 ECHA Information on Registered Substances 2 Warheit DB, Hoke RA, Finlay C, Donner EM, Reed KL, Sayes CM Development of a base set of toxicity tests using ultrafine TiO2 particles as a component of nanoparticle risk management PMID: 17566673, Toxicology Letters 2007 2017/01/22
甲殻類 Daphnia magna mortality EC50 48 hours 359.9 mg/L 12 ECHA Information on Registered Substances 4 study report 2009 2017/01/23
甲殻類 Daphnia magna mobility LL50 48 hours >1000 mg/L ○ 12 ECHA Information on Registered Substances 2 study report 1993 2017/01/23
甲殻類 Daphnia magna EC50 48 hours >1000 mg/L ○ 12 ECHA Information on Registered Substances 2 publication 1993 2017/01/23
甲殻類 Daphnia magna mobility LL50 48 hours >12.5 mmol/L ○ 12 ECHA Information on Registered Substances 2 study report 1993 2017/01/23
甲殻類 Daphnia magna mortality EC50 48 hours 359.9 mg/L 12 ECHA Information on Registered Substances 4 study report 2009 2017/01/23
甲殻類 Daphnia magna EC50 48 hours >1000 mg/L ○ 12 ECHA Information on Registered Substances 2 publication 1993 2017/01/23
甲殻類 Daphnia magna EC50 48 hours >1000 mg/L ○ 12 ECHA Information on Registered Substances 2 publication 1993 2017/01/23
甲殻類 Daphnia magna EC50 48 hours >1000 mg/L ○ 12 ECHA Information on Registered Substances 2 publication 1993 2017/01/23
甲殻類 Daphnia magna EC50 48 hours >1000 mg/L ○ 12 ECHA Information on Registered Substances 2 publication 1993 2017/01/23
甲殻類 Daphnia magna EC50 48 hours >1000 mg/L ○ 12 ECHA Information on Registered Substances 2 publication 1993 2017/01/23
甲殻類 Daphnia magna EC50 48 hours >1000 mg/L ○ 12 ECHA Information on Registered Substances 2 publication 1993 2017/03/07
甲殻類 Daphnia magna EC50 48 hours >1000 mg/L ○ 12 ECHA Information on Registered Substances 2 publication 1993 2017/01/23
甲殻類 Daphnia magna mobility LL50 48 hours >1.25 mmol/L 12 ECHA Information on Registered Substances 2 Warheit DB, Hoke RA, Finlay C, Donner EM, Reed KL, Sayes CM Development of a base set of toxicity tests using ultrafine TiO2 particles as a component of nanoparticle risk management PMID: 17566673, Toxicology Letters 2007 2017/01/23
甲殻類 Daphnia magna EC50 48 hours >1000 mg/L ○ 12 ECHA Information on Registered Substances 2 publication 1993 2017/01/23
甲殻類 Daphnia magna mortality EC50 48 hours 359.9 mg/L 12 ECHA Information on Registered Substances 4 study report 2009 2017/01/23
甲殻類 Daphnia magna EC50 48 hours >1000 mg/L ○ 12 ECHA Information on Registered Substances 2 publication 1993 2017/01/23
甲殻類 Daphnia magna reproduction EL100 30 days 500 mg/L × 12 ECHA Information on Registered Substances 4 Beim et al publication Vopr. Toksikol. I Sravnit. Fiziol., Yaroslavl 54-60. From: Ref. Zh. Khim. 1983. Abstr. N° 17I229. 1982 2017/01/23
甲殻類 Daphnia magna reproduction NOELR 30 days 100 mg/L × 12 ECHA Information on Registered Substances 4 Beim et al publication Vopr. Toksikol. I Sravnit. Fiziol., Yaroslavl 54-60. From: Ref. Zh. Khim. 1983. Abstr. N° 17I229. 1982 2017/01/23
甲殻類 Daphnia magna mortality LL100 18 days 1000 mg/L × 12 ECHA Information on Registered Substances 4 Beim et al publication Vopr. Toksikol. I Sravnit. Fiziol., Yaroslavl 54-60. From: Ref. Zh. Khim. 1983. Abstr. N° 17I229. 1982 2017/01/23
甲殻類 Daphnia magna reproduction NOELR 30 days 1.25 mmol/L × 12 ECHA Information on Registered Substances 4 Beim et al publication Vopr. Toksikol. I Sravnit. Fiziol., Yaroslavl 54-60. From: Ref. Zh. Khim. 1983. Abstr. N° 17I229. 1982 2017/01/23
魚類 Pimephales promelas (Fathead minnow) mortality LL50 96 hours >12.5 mmol/L ○ 12 ECHA Information on Registered Substances 2 study report 1992 2017/01/22
魚類 Pimephales promelas (Fathead minnow) mortality LL50 96 hours >1000 mg/L ○ 12 ECHA Information on Registered Substances 2 study report 1992 2017/03/05
魚類 Cyprinodon variegatus (Sheepshead minnow) mortality NOELR 96 hours >=10000 mg/L ○ 12 ECHA Information on Registered Substances 2 study report 2007 2017/01/22
魚類 Cyprinodon variegatus (Sheepshead minnow) mortality NOELR 96 hours >=125.16 mmol/L ○ 12 ECHA Information on Registered Substances 2 study report 2007 2017/01/22