生態影響に係る有害性情報


CAS登録番号 CAS RN ® : 7696-12-0
官報公示整理番号 METI No. : 9-839
物質名 test material : (1,3-ジオキソ-4,5,6,7-テトラヒドロイソインドリン-2-イル)メチル=2,2-ジメチル-3-(2-メチルプロパ-1-エン-1-イル)シクロプロパン-1-カルボキシラート /(1,3-Dioxo-4,5,6,7-tetrahydroisoindolin-2-yl)methyl 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate
水溶解度 water solubility : 1.83mg/L (実測値 measured)
LogKow
備考 remarks
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書) / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし 4:情報が少なく評価不能
日本環境省 化学物質の環境リスク評価(生態リスク初期評価) A:試験は信頼できる B:試験は条件付きで信頼できる C:試験の信頼性は低い D:信頼性の判定不可 E:信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり Supplemental:条件付きで信頼性あり Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり:○
なし:×
情報源 情報源による
信頼性評価**
著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value
exposure
duration
unit
toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material
original work type original work
reliability rank
author title referenced journal publication year Information
update date
甲殻類 Daphnia magna Physiology NOEL 2 days 24 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly: Environmental Effects Database (EEDB)) Environmental Fate and Effects Division, U.S.EPA, Washington, D.C.: 1992 2016/03/25
甲殻類 Daphnia magna Physiology EC50 2 days 45 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly: Environmental Effects Database (EEDB)) Environmental Fate and Effects Division, U.S.EPA, Washington, D.C.: 1992 2016/03/25
甲殻類 Daphnia pulex LC50 3 hours >50 mg/L 10 EHC (Environmental Health Criteria) MIYAMOTO, J. Degradation, metabolism and toxicity of synthetic pyrethroids Environ. Health Perspect., 14 2022/02/15
甲殻類 Daphnia pulex LC50 3 hours >50 mg/L 10 EHC (Environmental Health Criteria) MIYAMOTO, J. Degradation, metabolism and toxicity of synthetic pyrethroids Environ. Health Perspect., 14 2022/01/19
甲殻類 Daphnia pulex LC50 3 hours >50 mg/L 10 EHC (Environmental Health Criteria) MIYAMOTO, J. Degradation, metabolism and toxicity of synthetic pyrethroids Environ. Health Perspect., 14 2022/01/19
甲殻類 Daphnia magna EC50 48 hours 45 μg/L 3 USEPA Pesticide Ecotoxicity Database J. Noles 1992 2016/02/02
甲殻類 Daphnia magna NOEL 48 hours 24 μg/L 3 USEPA Pesticide Ecotoxicity Database J. Noles 1992 2016/02/02
魚類 Danio rerio (Zebrafish) Mortality LC95 3 days 85.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zhang,Z.Y., X.Y. Yu, D.L. Wang, H.J. Yan, and X.J. Liu Acute Toxicity to Zebrafish of Two Organophosphates and Four Pyrethroids and Their Binary Mixtures Pest Manage. Sci.66(1): 84-89 2010 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC95 1 days 116 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zhang,Z.Y., X.Y. Yu, D.L. Wang, H.J. Yan, and X.J. Liu Acute Toxicity to Zebrafish of Two Organophosphates and Four Pyrethroids and Their Binary Mixtures Pest Manage. Sci.66(1): 84-89 2010 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC95 4 days 58.1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zhang,Z.Y., X.Y. Yu, D.L. Wang, H.J. Yan, and X.J. Liu Acute Toxicity to Zebrafish of Two Organophosphates and Four Pyrethroids and Their Binary Mixtures Pest Manage. Sci.66(1): 84-89 2010 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC95 2 days 87.9 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zhang,Z.Y., X.Y. Yu, D.L. Wang, H.J. Yan, and X.J. Liu Acute Toxicity to Zebrafish of Two Organophosphates and Four Pyrethroids and Their Binary Mixtures Pest Manage. Sci.66(1): 84-89 2010 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 4 days 46 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zhang,Z.Y., X.Y. Yu, D.L. Wang, H.J. Yan, and X.J. Liu Acute Toxicity to Zebrafish of Two Organophosphates and Four Pyrethroids and Their Binary Mixtures Pest Manage. Sci.66(1): 84-89 2010 2016/03/25
魚類 Cyprinus carpio (Carp) Mortality LC50 4 days 120 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Sun,F. Evaluating Acute Toxicity of Pesticides to Aquatic Organisms: Carp, Mosquito Fish and Daphnids Zhiwu Baohu Xuehui Huikan (Plant Prot. Bull. (Taichung))29(4): 385-396 1987 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 2 days 51.7 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zhang,Z.Y., X.Y. Yu, D.L. Wang, H.J. Yan, and X.J. Liu Acute Toxicity to Zebrafish of Two Organophosphates and Four Pyrethroids and Their Binary Mixtures Pest Manage. Sci.66(1): 84-89 2010 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 3 days 48.4 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zhang,Z.Y., X.Y. Yu, D.L. Wang, H.J. Yan, and X.J. Liu Acute Toxicity to Zebrafish of Two Organophosphates and Four Pyrethroids and Their Binary Mixtures Pest Manage. Sci.66(1): 84-89 2010 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 1 days 78.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zhang,Z.Y., X.Y. Yu, D.L. Wang, H.J. Yan, and X.J. Liu Acute Toxicity to Zebrafish of Two Organophosphates and Four Pyrethroids and Their Binary Mixtures Pest Manage. Sci.66(1): 84-89 2010 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality NOEL 4 days <12 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly: Environmental Effects Database (EEDB)) Environmental Fate and Effects Division, U.S.EPA, Washington, D.C.: 1992 2016/03/25
魚類 Cyprinus carpio (Carp) Mortality LC50 2 days 240 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Sun,F. Evaluating Acute Toxicity of Pesticides to Aquatic Organisms: Carp, Mosquito Fish and Daphnids Zhiwu Baohu Xuehui Huikan (Plant Prot. Bull. (Taichung))29(4): 385-396 1987 2016/03/25
魚類 Danio rerio (Zebrafish) No Group Code 5 days 80 μM 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Padilla,S., D. Corum, B. Padnos, D.L. Hunter, A. Beam, K.A. Houck, N. Sipes, N. Kleinstreuer, T. Knudsen, D.J. Dix, and Zebrafish Developmental Screening of the ToxCast Phase I Chemical Library Reprod. Toxicol.33(2): 174-187 2012 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality NOEL 4 days 8 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly: Environmental Effects Database (EEDB)) Environmental Fate and Effects Division, U.S.EPA, Washington, D.C.: 1992 2016/03/25
魚類 Danio rerio (Zebrafish) No Group Code EC10 5 days 7.4592 μM 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Padilla,S., D. Corum, B. Padnos, D.L. Hunter, A. Beam, K.A. Houck, N. Sipes, N. Kleinstreuer, T. Knudsen, D.J. Dix, and Zebrafish Developmental Screening of the ToxCast Phase I Chemical Library Reprod. Toxicol.33(2): 174-187 2012 2016/03/25
魚類 Danio rerio (Zebrafish) No Group Code EC50 5 days 10.3323 μM 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Padilla,S., D. Corum, B. Padnos, D.L. Hunter, A. Beam, K.A. Houck, N. Sipes, N. Kleinstreuer, T. Knudsen, D.J. Dix, and Zebrafish Developmental Screening of the ToxCast Phase I Chemical Library Reprod. Toxicol.33(2): 174-187 2012 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 4 days 15.9 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly: Environmental Effects Database (EEDB)) Environmental Fate and Effects Division, U.S.EPA, Washington, D.C.: 1992 2016/03/25
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 4 days 19 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly: Environmental Effects Database (EEDB)) Environmental Fate and Effects Division, U.S.EPA, Washington, D.C.: 1992 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 4 days 21 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly: Environmental Effects Database (EEDB)) Environmental Fate and Effects Division, U.S.EPA, Washington, D.C.: 1992 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality NOEL 4 days 8 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly: Environmental Effects Database (EEDB)) Environmental Fate and Effects Division, U.S.EPA, Washington, D.C.: 1992 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 4 days 3.7 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly: Environmental Effects Database (EEDB)) Environmental Fate and Effects Division, U.S.EPA, Washington, D.C.: 1992 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality NOEL 4 days 2.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) U.S. Environmental Protection Agency Pesticide Ecotoxicity Database (Formerly: Environmental Effects Database (EEDB)) Environmental Fate and Effects Division, U.S.EPA, Washington, D.C.: 1992 2016/03/25
魚類 Oryzias latipes (Japanese medaka) LC50 48 hours 0.2 mg/L 10 EHC (Environmental Health Criteria) MIYAMOTO, J. Degradation, metabolism and toxicity of synthetic pyrethroids Environ. Health Perspect., 14 2022/01/19
魚類 Oryzias latipes (Japanese medaka) LC50 48 hours 0.2 mg/L 10 EHC (Environmental Health Criteria) MIYAMOTO, J. Degradation, metabolism and toxicity of synthetic pyrethroids Environ. Health Perspect., 14 2022/01/19
魚類 Lepomis macrochirus (Bluegill) LC50 96 hours 0.019 mg/L 10 EHC (Environmental Health Criteria) Written comment from US EPA to IPCS 2022/02/15
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours 0.021 mg/L 10 EHC (Environmental Health Criteria) Written comment from US EPA to IPCS 2022/02/15
魚類 Oryzias latipes (Japanese medaka) LC50 48 hours 0.15 mg/L 10 EHC (Environmental Health Criteria) MIYAMOTO, J. Degradation, metabolism and toxicity of synthetic pyrethroids Environ. Health Perspect., 14 2022/01/19
魚類 Lepomis macrochirus (Bluegill) LC50 96 hours 19 μg/L 3 USEPA Pesticide Ecotoxicity Database R. Matheny 1979 2016/02/02
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours 21 μg/L 3 USEPA Pesticide Ecotoxicity Database R. Matheny 1979 2016/02/02
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours 8.2 μg/L 3 USEPA Pesticide Ecotoxicity Database J. McCann 1972 2016/02/02
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours 3.7 μg/L 3 USEPA Pesticide Ecotoxicity Database J. Noles 1992 2016/02/02
魚類 Lepomis macrochirus (Bluegill) LC50 96 hours 15.9 μg/L 3 USEPA Pesticide Ecotoxicity Database J. Noles 1992 2016/02/02
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours 8.2 ppb 3 USEPA Pesticide Ecotoxicity Database J. McCann 1972 2018/03/22
魚類 Lepomis macrochirus (Bluegill) NOEL 96 hours 12 μg/L 3 USEPA Pesticide Ecotoxicity Database J. Noles 1992 2016/02/02
魚類 Lepomis macrochirus (Bluegill) NOEL 96 hours 8 μg/L 3 USEPA Pesticide Ecotoxicity Database R. Matheny 1979 2016/02/02
魚類 Oncorhynchus mykiss (Rainbow trout) NOEL 96 hours 8 μg/L 3 USEPA Pesticide Ecotoxicity Database R. Matheny 1979 2016/02/02
魚類 Oncorhynchus mykiss (Rainbow trout) NOEL 96 hours 2.2 μg/L 3 USEPA Pesticide Ecotoxicity Database J. Noles 1992 2016/02/02
魚類 Oncorhynchus mykiss (Rainbow trout) NOEL 96 hours 3.2 μg/L 3 USEPA Pesticide Ecotoxicity Database J. McCann 1972 2016/02/02
魚類 Oncorhynchus mykiss (Rainbow trout) NOEL 96 hours 3.2 ppb 3 USEPA Pesticide Ecotoxicity Database J. McCann 1972 2018/03/22