生態影響に係る有害性情報


CAS登録番号 CAS RN ® ： 7791-20-0
官報公示整理番号　METI No. ： 1-242
物質名 test material ： 塩化ニッケル（ＩＩ）・六水和物　／Nickel(II)chloride
水溶解度 water solubility ： 83740mg/L (推計値 estimated)
LogKow ： 0.05 (推計値 estimated)
備考 remarks ：
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書） / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし　4:情報が少なく評価不能
日本環境省　化学物質の環境リスク評価（生態リスク初期評価） A：試験は信頼できる　B：試験は条件付きで信頼できる　C：試験の信頼性は低い　D：信頼性の判定不可　E：信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり　Supplemental:条件付きで信頼性あり　Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり：○
なし：×		 情報源 情報源による
信頼性評価**		 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value		 exposure
duration
unit		 toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material		 original work type original work
reliability rank		 author title referenced journal publication year Information
update date
藻類 Dunaliella tertiolecta Population/Photosynthesis EC50 1 hours 6342 mg/L × 16 ECOTOX McFeters,G.A., P.J. Bond, S.B. Olson, and Y.T. Tchan A Comparison of Microbial Bioassays for the Detection of Aquatic Toxicants Water Res.17(12) 2020/11/12
藻類 Chlorella sp. Chlorella pyrenoidosa 生長阻害 生長速度 LOEC 14 days 8 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Wong, P.K. and Wong, C.K. Toxicity of nickel and nickel electroplating water to Chlorella pyrenoidosa Bull.Environ.Contam.Toxicol. 1990 2018/03/22
藻類 Selenastrum capricornutum 生長阻害 ﾊﾞｲｵﾏｽ NOEC 96 hours 0.01 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Chao, M.R. and Chen, C.Y. No-observed-effect concentrations in batch and continuous algal toxicity tests Environ.Toxicol.Chem. 2000 2018/03/22
藻類 Selenastrum capricornutum 生長阻害 生長速度 NOEC 96 hours 0.01 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Chao, M.R. and Chen, C.Y. No-observed-effect concentrations in batch and continuous algal toxicity tests Environ.Toxicol.Chem. 2000 2018/03/22
藻類 Chlorella sp. Chlorella pyrenoidosa 生長阻害 生長速度 NOEC 14 days 4 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Wong, P.K. and Wong, C.K. Toxicity of nickel and nickel electroplating water to Chlorella pyrenoidosa Bull.Environ.Contam.Toxicol. 1990 2018/03/22
藻類 Chlorella sp. Chlorella pyrenoidosa 生長阻害 ﾊﾞｲｵﾏｽ LOEC 14 days 8 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Wong, P.K. and Wong, C.K. Toxicity of nickel and nickel electroplating water to Chlorella pyrenoidosa Bull.Environ.Contam.Toxicol. 1990 2018/03/22
藻類 Chlorella sp. Chlorella pyrenoidosa 生長阻害 ﾊﾞｲｵﾏｽ NOEC 14 days 4 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Wong, P.K. and Wong, C.K. Toxicity of nickel and nickel electroplating water to Chlorella pyrenoidosa Bull.Environ.Contam.Toxicol. 1990 2018/03/22
藻類 Selenastrum capricornutum 生長阻害, 生長速度 LOEC 96 hours 0.03 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Chao, M.R. and Chen, C.Y. No-observed-effect concentrations in batch and continuous algal toxicity tests Environ.Toxicol.Chem. 2000 2018/03/22
藻類 Selenastrum capricornutum 生長阻害, ﾊﾞｲｵﾏｽ LOEC 96 hours 0.03 mg/L mg NI/L 8 NITE 化学物質の初期リスク評価書 Chao, M.R. and Chen, C.Y. No-observed-effect concentrations in batch and continuous algal toxicity tests Environ.Toxicol.Chem. 2000 2018/03/22
甲殻類 Mysidopsis bahia Mortality 4 days 974 μg/L TOTAL 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Lussier,S.M., W.S. Boothman, S. Poucher, D. Champlin, and A. Helmstetten Comparison of Dissolved and Total Metals Concentrations from Acute Tests with Saltwater Organisms Environ. Toxicol. Chem.18(5): 889-898 1999 2018/03/20
甲殻類 Daphnia sp. Daphnia pulex mortality LC50 48 hours 26 μmol/L 12 ECHA Information on Registered Substances 2 Leonard EM, Wood CM Acute toxicity, critical body residues, Michaelis-Menten analysis of bioaccumulation, and ionoregulatory disturbance in response to waterborne nickel in four invertebrates: Chironomus riparius, Lymnaea stagnalis, Lumbriculus variegatus and Daphnia pulex Comparative Biochemistry and Physiology, Part C 2013 2018/01/30
甲殻類 Ceriodaphnia dubia mortality LC50 48 hours 276 μg/L dissolved 12 ECHA Information on Registered Substances 1 study report 2005 2018/02/24
甲殻類 Daphnia sp. Daphnia pulex LC50 48 hours 0.912 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Jindal, R. and Verma, A. Heavy metal toxicity to Daphnia pulex Indian J.Environ.Health 1990 2018/03/22
甲殻類 Ceriodaphnia dubia mortality LC50 48 hours 74.4 μg/L dissolved 12 ECHA Information on Registered Substances 1 study report 2005 2018/02/24
甲殻類 Daphnia magna 遊泳阻害 EC50 48 hours 1.92 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Chapman, G.A., Ota, S. and Recht, F. Effects of water hardness on the toxicity of metals to Daphnia magna U.S.EPA, Corvallis, OR 1980 2018/03/22
甲殻類 Daphnia magna 遊泳阻害 EC50 48 hours 0.51 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Biesinger, K.E. and Christensen, G.M. Effects of various metals on survival, growth, reproduction and metabolism of Daphnia magna J.Fish Res.Board Can. 1972 2018/03/22
甲殻類 Ceriodaphnia dubia LC50 48 hours 0.14 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Schubauer-Berigan, M.K., Dierkes, J.R. Monson, P.D. and Ankley, G.T. pH-dependent toxicity of Cd, Cu, Ni, Pb and Zn to Ceriodaphnia dubia, Pimephales promelas, Hyalella azteca and Lumbriculus variegates. Environ.Toxicol.Chem. 1993 2018/03/22
甲殻類 Ceriodaphnia dubia mortality LC50 48 hours 87.5 μg/L dissolved 12 ECHA Information on Registered Substances 1 study report 2005 2018/02/24
甲殻類 Daphnia magna immobilization EC50 48 hours >=0.86～<=6.3 12 ECHA Information on Registered Substances 2 study report 2005 2018/02/24
甲殻類 Ceriodaphnia dubia mortality LC50 48 hours 121.6 μg/L dissolved 12 ECHA Information on Registered Substances 1 study report 2005 2018/02/24
甲殻類 Daphnia sp. Daphnia pulex mortality LC50 48 hours 7.5 μmol/L 12 ECHA Information on Registered Substances 2 Leonard EM, Wood CM Acute toxicity, critical body residues, Michaelis-Menten analysis of bioaccumulation, and ionoregulatory disturbance in response to waterborne nickel in four invertebrates: Chironomus riparius, Lymnaea stagnalis, Lumbriculus variegatus and Daphnia pulex Comparative Biochemistry and Physiology, Part C 2013 2018/01/30
甲殻類 Crassostrea gigas EC50 48 hours 349 μg/L 12 ECHA Information on Registered Substances Martin, M., K.E. Osborn, P. Billig, and N. Glickstein. Toxicities of ten metals to Crassostrea gigas and Mytilus edulis embryos and Cancer magister larvae. Mar. Pollut. Bull. 1981 2018/01/30
甲殻類 Daphnia magna 遊泳阻害 EC50 48 hours 2.36 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Chapman, G.A., Ota, S. and Recht, F. Effects of water hardness on the toxicity of metals to Daphnia magna U.S.EPA, Corvallis, OR 1980 2018/03/22
甲殻類 Daphnia magna mortality LC50 48 hours 0.915 mg/L element, Ni+2 12 ECHA Information on Registered Substances 2 Call, D.J., L.T. Brooke, N. Ahmad, and J.E. Richter. Toxicity and metabolism studies with EPA priority pollutants and related chemicals in freshwater organisms. PB83-263665/EPA-600/3-83-095. National Technical Information Service (NTIS). Springfield, VA. 120p. 1983 2018/01/30
甲殻類 Ceriodaphnia dubia LC50 48 hours >0.2 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Schubauer-Berigan, M.K., Dierkes, J.R. Monson, P.D. and Ankley, G.T. pH-dependent toxicity of Cd, Cu, Ni, Pb and Zn to Ceriodaphnia dubia, Pimephales promelas, Hyalella azteca and Lumbriculus variegates. Environ.Toxicol.Chem. 1993 2018/03/22
甲殻類 Americamysis bahia Mortality/Mortality NR-LETH 96 hours 974 μg/L ○ 16 ECOTOX Lussier,S.M., W.S. Boothman, S. Poucher, D. Champlin, and A. Helmstetten Comparison of Dissolved and Total Metals Concentrations from Acute Tests with Saltwater Organisms Environ. Toxicol. Chem.18(5) 2020/11/12
甲殻類 Americamysis bahia Mortality LC50 96 hours 0.634 mg Ni/L measured ○ 8 NITE 化学物質の初期リスク評価書 Gentile, S. and Cardin J. Unpublished laboratory data. U.S.EPA, Narragansett, RI 2021/04/06
甲殻類 Daphnia pulex Mortality LC50 48 hours 0.912 mg Ni/L measured ○ 8 NITE 化学物質の初期リスク評価書 Jindal, R. and Verma, A. Heavy metal toxicity to Daphnia pulex. Indian J.Environ.Health, 32 2021/04/06
甲殻類 Crassostrea virginica Mortality LC50 48 hours 1.18 mg Ni/L nominal 8 NITE 化学物質の初期リスク評価書 Calabrese, A., Collier, R.S., Nelson, D.A. and Mac Innes, J.R. The Toxicity of heavy metals to embryos of the american oyster Crassostrea virginica. Mar.Biol., 18 2021/04/06
甲殻類 Nitocra spinipes Mortality LC50 96 hours 6 mg Ni/L nominal 8 NITE 化学物質の初期リスク評価書 Bengtsson, B.E. Use of a harpacticoid copepod in toxicity tests. Mar.Pollut.Bull., 9 2021/04/06
甲殻類 Daphnia magna 遊泳阻害 EC50 48 hours 4.97 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Chapman, G.A., Ota, S. and Recht, F. Effects of water hardness on the toxicity of metals to Daphnia magna U.S.EPA, Corvallis, OR 1980 2018/03/22
甲殻類 Nitocra spinipes LC50 96 hours 6 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Bengtsson, B.E. Use of a harpacticoid copepod in toxicity tests Mar.Pollut.Bull. 1978 2018/03/22
甲殻類 Crassostrea virginica LC50 48 hours 1.18 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Calabrese, A., Collier, R.S., Nelson, D.A. and Mac Innes, J.R. The Toxicity of heavy metals to embryos of the american oyster Crassostrea virginica. Mar.Biol. 1973 2018/03/22
甲殻類 Daphnia magna 遊泳阻害 EC50 48 hours 1.8 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Chapman, G.A., Ota, S. and Recht, F. Effects of water hardness on the toxicity of metals to Daphnia magna U.S.EPA, Corvallis, OR 1980 2018/03/22
甲殻類 Ceriodaphnia dubia LC50 48 hours 0.013 mg/L 8 NITE 化学物質の初期リスク評価書 Schubauer-Berigan, M.K., Dierkes, J.R. Monson, P.D. and Ankley, G.T. pH-dependent toxicity of Cd, Cu, Ni, Pb and Zn to Ceriodaphnia dubia, Pimephales promelas, Hyalella azteca and Lumbriculus variegates. Environ.Toxicol.Chem. 1993 2018/03/22
甲殻類 Ceriodaphnia dubia reproduction EC10 7 days >2.8～<53.6 12 ECHA Information on Registered Substances 1 study report 2004 2018/01/30
甲殻類 Mysidopsis bahia Survival and reproduction LOEC 36 days 0.141 mg/L 12 ECHA Information on Registered Substances 2 Gentile, J.H., Gentile, S.M., Hairston, N.G., and B.K. Sullivan. The Use of Life-tables for Evaluating the Chronic Toxicity of Pollutants to Mysidopsis bahia . Hydrobiol. J. 1982 2018/01/30
甲殻類 Mysidopsis bahia Survival and reproduction NOEC 36 days 0.061 mg/L 12 ECHA Information on Registered Substances 2 Gentile, J.H., Gentile, S.M., Hairston, N.G., and B.K. Sullivan. The Use of Life-tables for Evaluating the Chronic Toxicity of Pollutants to Mysidopsis bahia . Hydrobiol. J. 1982 2018/01/30
甲殻類 Daphnia magna 繁殖 EC50 21 days 0.095 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Biesinger, K.E. and Christensen, G.M. Effects of various metals on survival, growth, reproduction and metabolism of Daphnia magna J.Fish Res.Board Can. 1972 2018/03/22
甲殻類 Daphnia magna 繁殖 LC50 21 days 0.13 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Biesinger, K.E. and Christensen, G.M. Effects of various metals on survival, growth, reproduction and metabolism of Daphnia magna J.Fish Res.Board Can. 1972 2018/03/22
甲殻類 Daphnia magna 繁殖 EC50 21 days 0.95 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Enserink, E.L., Maas-Diepeveen, J.L. and van Leeuwen, C.J. Combined effects of metals; an ecotoxicological evaluation. Water Res. 1991 2018/03/22
甲殻類 Daphnia magna 繁殖 LC50 21 days 0.36 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Enserink, E.L., Maas-Diepeveen, J.L. and van Leeuwen, C.J. Combined effects of metals; an ecotoxicological evaluation. Water Res. 1991 2018/03/22
魚類 Oryzias latipes (Japanese medaka) LC50 96 hours 11 mg/L 1 日本環境省　生態リスク初期評価 環境省 （Ⅱ-1）生態影響試験（藻類、甲殻類、魚類）結果一覧(平成29年3月版） 2018/02/19
魚類 Lepomis macrochirus (Bluegill) mortality LC50 96 hours 5.18 mg/L × 12 ECHA Information on Registered Substances 2 Pickering, Q.H. and C. Henderson The acute toxicity of some heavy metals to different species of warmwater Air Wat. Pollut. Int. J. 1966 2018/01/30
魚類 Cyprinus carpio (Carp) mortality LC50 96 hours 1.64 mg/L 12 ECHA Information on Registered Substances 2 Alam, M.K. and O.E. Maughan The effect of malathion, diazinon, and various concentrations of zinc, copper, nickel, lead, iron, and mercury on fish Biological Trace Element Research 1992 2018/01/30
魚類 Cyprinus carpio (Carp) mortality LC50 96 hours 1.3 mg/L 12 ECHA Information on Registered Substances 2 Alam, M.K. and O.E. Maughan The effect of malathion, diazinon, and various concentrations of zinc, copper, nickel, lead, iron, and mercury on fish Biological Trace Element Research 1992 2018/01/30
魚類 Fundulus heteroclitus (Mummichog) mortality LC50 24 hours >400 mg/L 12 ECHA Information on Registered Substances 2 Eisler, R. and R.J. Hennekey Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna Arch. Environ. Contam. Toxicol. 1977 2018/01/30
魚類 Lepomis macrochirus (Bluegill) mortality LC50 96 hours 5.36 mg/L × 12 ECHA Information on Registered Substances 2 Pickering, Q.H. and C. Henderson The acute toxicity of some heavy metals to different species of warmwater Air Wat. Pollut. Int. J. 1966 2018/01/30
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 1.68 mg/L 12 ECHA Information on Registered Substances 2 Hoang, T.C., J.R. Tomasso, and S.J. Klaine Influence of water quality and age on nickel toxicity to fathead minnows (Pimephales promelas) Environ. Toxicol. Chem. 2004 2018/01/30
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 2.21 mg/L 12 ECHA Information on Registered Substances 2 Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas) Water, Air, and Soil Pollution. 2002 2018/01/30
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 0.4 mg/L 12 ECHA Information on Registered Substances 2 Hoang, T.C., J.R. Tomasso, and S.J. Klaine Influence of water quality and age on nickel toxicity to fathead minnows (Pimephales promelas) Environ. Toxicol. Chem. 2004 2018/01/30
魚類 Poecilia reticulata (Guppy) mortality LC50 72 hours 18.72 mg/L element 12 ECHA Information on Registered Substances 1 Shuhaimi-Othman M, Yakub N, Ramle N-A, and Abas A. Comparative toxicity of eight metals on freshwater fish. Toxicology and Industrial Health 2012 2018/01/30
魚類 Fundulus heteroclitus (Mummichog) LC100 168 hours 250 mg/L 12 ECHA Information on Registered Substances 2 Eisler, R. and R.J. Hennekey Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna Arch. Environ. Contam. Toxicol. 1977 2018/01/30
魚類 Carassius auratus (Goldfish) mortality LC50 48 hours 20.5 mg/L × 12 ECHA Information on Registered Substances 2 Pickering, Q.H. and C. Henderson The acute toxicity of some heavy metals to different species of warmwater Air Wat. Pollut. Int. J. 1966 2018/01/30
魚類 Danio rerio (Zebrafish) NOEC 96 hours 32 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 1993 2018/01/30
魚類 Cyprinus carpio (Carp) mortality LC50 96 hours 1.54 mg/L 12 ECHA Information on Registered Substances 2 Alam, M.K. and O.E. Maughan The effect of malathion, diazinon, and various concentrations of zinc, copper, nickel, lead, iron, and mercury on fish Biological Trace Element Research 1992 2018/01/30
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 5.18 mg/L × 12 ECHA Information on Registered Substances 2 Pickering, Q.H. and C. Henderson The acute toxicity of some heavy metals to different species of warmwater Air Wat. Pollut. Int. J. 1966 2018/01/30
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 96 hours 13.7 mg/L × 12 ECHA Information on Registered Substances 2 U.S. EPA study report 1975 2018/01/30
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 96 hours 15.3 mg/L dissolved, Ni 12 ECHA Information on Registered Substances 2 Pane, E.F., J.G. Richards, and C.M. Wood Acute waterborne nickel toxicity in the rainbow trout (Oncorhynchus mykiss) occurs by a respiratory rather than a ionoregulatory mechanism Aquatic Toxicology 2003 2018/01/30
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 96 hours 8.1 mg/L 12 ECHA Information on Registered Substances 1 Nebeker, A.V., C. Savonen, and D.G. Stevens Sensitivity of rainbow trout early life stages to nickel chloride Environmental Toxicology and Chemistry 1985 2018/02/25
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 0.5 mg/L 12 ECHA Information on Registered Substances 2 Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas) Water, Air, and Soil Pollution. 2002 2018/01/30
魚類 Poecilia reticulata (Guppy) mortality LC50 24 hours 54.43 mg/L element 12 ECHA Information on Registered Substances 1 Shuhaimi-Othman M, Yakub N, Ramle N-A, and Abas A. Comparative toxicity of eight metals on freshwater fish. Toxicology and Industrial Health 2012 2018/01/30
魚類 Danio rerio (Zebrafish) embryotoxicity NOEC 24 hours 200 mg/L element, nickel 12 ECHA Information on Registered Substances 2 Ku T, Yan W, Jia W, Yun Y, Zhu N, Li G, Sang N. Characterization of synergistic embryotoxicity of nickel and buprofezin in zebrafish. Environ Sci Technol. 2015 2018/01/30
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 96 hours 16.3 mg/L × 12 ECHA Information on Registered Substances 2 U.S. EPA study report 1975 2018/01/30
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 1.12 mg/L 12 ECHA Information on Registered Substances 2 Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas) Water, Air, and Soil Pollution. 2002 2018/01/30
魚類 Oncorhynchus mykiss (Rainbow trout) mortality NOEC 96 hours 4.9 mg/L × 12 ECHA Information on Registered Substances 2 U.S. EPA study report 1975 2018/01/30
魚類 Lepomis macrochirus (Bluegill) mortality LC50 24 hours 41.7 mg/L × 12 ECHA Information on Registered Substances 2 Pickering, Q.H. and C. Henderson The acute toxicity of some heavy metals to different species of warmwater Air Wat. Pollut. Int. J. 1966 2018/01/30
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 96 hours 8.9 mg/L 12 ECHA Information on Registered Substances 1 Nebeker, A.V., C. Savonen, and D.G. Stevens Sensitivity of rainbow trout early life stages to nickel chloride Environmental Toxicology and Chemistry 1985 2018/02/25
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours 5～45 × 12 ECHA Information on Registered Substances 2 Pickering, Q.H. and C. Henderson The acute toxicity of some heavy metals to different species of warmwater Air Wat. Pollut. Int. J. 1966 2018/01/30
魚類 Lepomis macrochirus (Bluegill) mortality LC50 48 hours 8.67 mg/L × 12 ECHA Information on Registered Substances 2 Pickering, Q.H. and C. Henderson The acute toxicity of some heavy metals to different species of warmwater Air Wat. Pollut. Int. J. 1966 2018/01/30
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 4.58 mg/L × 12 ECHA Information on Registered Substances 2 Pickering, Q.H. and C. Henderson The acute toxicity of some heavy metals to different species of warmwater Air Wat. Pollut. Int. J. 1966 2018/01/30
魚類 Cyprinus carpio (Carp) mortality LC50 96 hours 2.3 mg/L 12 ECHA Information on Registered Substances 2 Alam, M.K. and O.E. Maughan The effect of malathion, diazinon, and various concentrations of zinc, copper, nickel, lead, iron, and mercury on fish Biological Trace Element Research 1992 2018/01/30
魚類 Carassius auratus (Goldfish) mortality LC50 96 hours 9.82 mg/L × 12 ECHA Information on Registered Substances 2 Pickering, Q.H. and C. Henderson The acute toxicity of some heavy metals to different species of warmwater Air Wat. Pollut. Int. J. 1966 2018/01/30
魚類 Lepomis macrochirus (Bluegill) mortality LC50 48 hours 82.1 mg/L × 12 ECHA Information on Registered Substances 2 Pickering, Q.H. and C. Henderson The acute toxicity of some heavy metals to different species of warmwater Air Wat. Pollut. Int. J. 1966 2018/01/30
魚類 Carassius auratus (Goldfish) mortality LC50 24 hours 34.1 mg/L × 12 ECHA Information on Registered Substances 2 Pickering, Q.H. and C. Henderson The acute toxicity of some heavy metals to different species of warmwater Air Wat. Pollut. Int. J. 1966 2018/01/30
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 96 hours 10.9 mg/L 12 ECHA Information on Registered Substances 1 Nebeker, A.V., C. Savonen, and D.G. Stevens Sensitivity of rainbow trout early life stages to nickel chloride Environmental Toxicology and Chemistry 1985 2018/02/25
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 96 hours 10 mg/L 12 ECHA Information on Registered Substances 1 Nebeker, A.V., C. Savonen, and D.G. Stevens Sensitivity of rainbow trout early life stages to nickel chloride Environmental Toxicology and Chemistry 1985 2018/02/25
魚類 Fundulus heteroclitus (Mummichog) mortality NOEC 96 hours 250 mg/L 12 ECHA Information on Registered Substances 2 Eisler, R. and R.J. Hennekey Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna Arch. Environ. Contam. Toxicol. 1977 2018/01/30
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 96 hours 21.2 mg/L dissolved × 12 ECHA Information on Registered Substances 1 Brix, K.V., J. Keithly, D.K. DeForest, and J. Laughlin Acute and Chronic Toxicity of Nickel to Rainbow Trout (Oncorhynchus mykiss). Environmental Toxicology and Chemistry 2004 2018/01/30
魚類 Fundulus heteroclitus (Mummichog) LC50 168 hours 150 mg/L 12 ECHA Information on Registered Substances 2 Eisler, R. and R.J. Hennekey Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna Arch. Environ. Contam. Toxicol. 1977 2018/01/30
魚類 Danio rerio (Zebrafish) LOEC 96 hours >100 mg/L ○ 12 ECHA Information on Registered Substances 1 study report 1993 2018/01/30
魚類 Fundulus heteroclitus (Mummichog) NOEC 168 hours 50 mg/L 12 ECHA Information on Registered Substances 2 Eisler, R. and R.J. Hennekey Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna Arch. Environ. Contam. Toxicol. 1977 2018/01/30
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 0.45 mg/L 12 ECHA Information on Registered Substances 2 Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas) Water, Air, and Soil Pollution. 2002 2018/01/30
魚類 Oryzias latipes (Japanese medaka) LC50 24 hours >40 mg/L 塩化ニッケル（無水物） 11 Japan チャレンジプログラム 2018/03/14
魚類 Oryzias latipes (Japanese medaka) LC50 48 hours 36 mg/L 塩化ニッケル（無水物） 11 Japan チャレンジプログラム 2018/03/14
魚類 Oryzias latipes (Japanese medaka) LC50 96 hours 11 mg/L 塩化ニッケル（無水物） 11 Japan チャレンジプログラム 2018/03/14
魚類 Fundulus heteroclitus (Mummichog) mortality LC50 96 hours 350 mg/L 12 ECHA Information on Registered Substances 2 Eisler, R. and R.J. Hennekey Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna Arch. Environ. Contam. Toxicol. 1977 2018/01/30
魚類 Fundulus heteroclitus (Mummichog) mortality LC100 96 hours 400 mg/L 12 ECHA Information on Registered Substances 2 Eisler, R. and R.J. Hennekey Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna Arch. Environ. Contam. Toxicol. 1977 2018/01/30
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 42.4 mg/L × 12 ECHA Information on Registered Substances 2 Pickering, Q.H. and C. Henderson The acute toxicity of some heavy metals to different species of warmwater Air Wat. Pollut. Int. J. 1966 2018/01/30
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 44.5 mg/L × 12 ECHA Information on Registered Substances 2 Pickering, Q.H. and C. Henderson The acute toxicity of some heavy metals to different species of warmwater Air Wat. Pollut. Int. J. 1966 2018/01/30
魚類 Lepomis macrochirus (Bluegill) mortality LC50 96 hours 21.2 mg/L 12 ECHA Information on Registered Substances 2 Cairns, J., K.W. Thompson, and A.C. Hendricks Effects of Fluctuating, Sublethal Applications of Heavy Metal Solutions Upon the Gill Ventilation Response of Bluegills (Lepomis macrochirus) PB81-150997 or EPA-600/3-81-003. 1981 2018/01/30
魚類 Lepomis macrochirus (Bluegill) mortality NOEC 96 hours 37 mg/L × 12 ECHA Information on Registered Substances 2 US EPA study 1975 2018/01/30
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 24 hours 196 mg/L × 12 ECHA Information on Registered Substances 2 U.S. EPA study report 1975 2018/01/30
魚類 Poecilia reticulata (Guppy) mortality LC50 48 hours 29.66 mg/L element 12 ECHA Information on Registered Substances 1 Shuhaimi-Othman M, Yakub N, Ramle N-A, and Abas A. Comparative toxicity of eight metals on freshwater fish. Toxicology and Industrial Health 2012 2018/01/30
魚類 Danio rerio (Zebrafish) LC50 96 hours 100～320 ○ 12 ECHA Information on Registered Substances 1 study report 1993 2018/01/30
魚類 Fundulus heteroclitus (Mummichog) mortality NOEC 24 hours 400 mg/L 12 ECHA Information on Registered Substances 2 Eisler, R. and R.J. Hennekey Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna Arch. Environ. Contam. Toxicol. 1977 2018/01/30
魚類 Lepomis macrochirus (Bluegill) mortality LC50 48 hours 115 mg/L × 12 ECHA Information on Registered Substances 2 US EPA study 1975 2018/01/30
魚類 Lepomis macrochirus (Bluegill) mortality LC50 48 hours 15.9 mg/L × 12 ECHA Information on Registered Substances 2 Pickering, Q.H. and C. Henderson The acute toxicity of some heavy metals to different species of warmwater Air Wat. Pollut. Int. J. 1966 2018/01/30
魚類 Lepomis macrochirus (Bluegill) mortality LC50 24 hours 11.3 mg/L × 12 ECHA Information on Registered Substances 2 Pickering, Q.H. and C. Henderson The acute toxicity of some heavy metals to different species of warmwater Air Wat. Pollut. Int. J. 1966 2018/01/30
魚類 Lepomis macrochirus (Bluegill) mortality LC50 24 hours 170 mg/L × 12 ECHA Information on Registered Substances 2 US EPA study 1975 2018/01/30
魚類 Lepomis macrochirus (Bluegill) mortality LC50 96 hours 62.2 mg/L × 12 ECHA Information on Registered Substances 2 US EPA study 1975 2018/01/30
魚類 Lepomis macrochirus (Bluegill) mortality NOEC 96 hours 42 mg/L × 12 ECHA Information on Registered Substances 2 US EPA study 1975 2018/01/30
魚類 Lepomis macrochirus (Bluegill) mortality LC50 48 hours 110 mg/L × 12 ECHA Information on Registered Substances 2 US EPA study 1975 2018/01/30
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 2.27 mg/L 12 ECHA Information on Registered Substances 2 Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas) Water, Air, and Soil Pollution. 2002 2018/01/30
魚類 Fundulus heteroclitus (Mummichog) mortality LC100 24 hours >400 mg/L 12 ECHA Information on Registered Substances 2 Eisler, R. and R.J. Hennekey Acute toxicities of Cd+2, Cr+6, Hg2+, Ni2+ and Zn2+ to estuarine macrofauna Arch. Environ. Contam. Toxicol. 1977 2018/01/30
魚類 Oncorhynchus mykiss (Rainbow trout) mortality NOEC 96 hours 5.6 mg/L × 12 ECHA Information on Registered Substances 2 U.S. EPA study report 1975 2018/01/30
魚類 Lepomis macrochirus (Bluegill) mortality LC50 96 hours 60.3 mg/L × 12 ECHA Information on Registered Substances 2 US EPA study 1975 2018/01/30
魚類 Poecilia reticulata (Guppy) mortality LC50 96 hours 15.62 mg/L element 12 ECHA Information on Registered Substances 1 Shuhaimi-Othman M, Yakub N, Ramle N-A, and Abas A. Comparative toxicity of eight metals on freshwater fish. Toxicology and Industrial Health 2012 2018/01/30
魚類 Lepomis macrochirus (Bluegill) mortality LC50 96 hours 39.6 mg/L × 12 ECHA Information on Registered Substances 2 Pickering, Q.H. and C. Henderson The acute toxicity of some heavy metals to different species of warmwater Air Wat. Pollut. Int. J. 1966 2018/01/30
魚類 Lepomis macrochirus (Bluegill) mortality LC50 24 hours 170 mg/L × 12 ECHA Information on Registered Substances 2 US EPA study 1975 2018/01/30
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 48 hours 51 mg/L × 12 ECHA Information on Registered Substances 2 U.S. EPA study report 1975 2018/01/30
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 0.54 mg/L 12 ECHA Information on Registered Substances 2 Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas) Water, Air, and Soil Pollution. 2002 2018/01/30
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 24 hours 312 mg/L × 12 ECHA Information on Registered Substances 2 U.S. EPA study report 1975 2018/01/30
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 0.69 mg/L 12 ECHA Information on Registered Substances 2 Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas) Water, Air, and Soil Pollution. 2002 2018/01/30
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 48 hours 94.3 mg/L × 12 ECHA Information on Registered Substances 2 U.S. EPA study report 1975 2018/01/30
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 0.35 mg/L 12 ECHA Information on Registered Substances 2 Pyle, G.G., S.M. Swanson, and D.M. Lehmkuhl The influence of water hardness, pH, and suspended solids on nickel toxicity to larval fathead minnows (Pimephales promelas) Water, Air, and Soil Pollution. 2002 2018/01/30
魚類 Oryzias latipes (Japanese medaka) Mortality NOEC 48 hours 10 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する急性毒性試験 No. 2006-生73 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality NOEC 24 hours 40 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する急性毒性試験 No. 2006-生73 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality LC0 72 hours 10 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する急性毒性試験 No. 2006-生73 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality LC100 96 hours 25 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する急性毒性試験 No. 2006-生73 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality LC100 72 hours 40 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する急性毒性試験 No. 2006-生73 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality LC100 48 hours >40 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する急性毒性試験 No. 2006-生73 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 24 hours >40 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する急性毒性試験 No. 2006-生73 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality NOEC 96 hours 4 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する急性毒性試験 No. 2006-生73 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality LC0 24 hours 40 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する急性毒性試験 No. 2006-生73 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality LC0 48 hours 10 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する急性毒性試験 No. 2006-生73 2008 2024/02/08
魚類 Pimephales promelas Mortality LC50 96 hours >4 mg Ni/L measured ○ 8 NITE 化学物質の初期リスク評価書 Schubauer-Berigan, M.K., Dierkes, J.R. Monson, P.D. and Ankley, G.T. pH-dependent toxicity of Cd, Cu, Ni, Pb and Zn to Ceriodaphnia dubia, Pimephales promelas, Hyalella azteca and Lumbriculus variegates. Environ.Toxicol.Chem., 12 2021/04/06
魚類 Oryzias latipes (Japanese medaka) Mortality LC100 24 hours >40 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する急性毒性試験 No. 2006-生73 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality NOEC 72 hours 4 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する急性毒性試験 No. 2006-生73 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 96 hours 11 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する急性毒性試験 No. 2006-生73 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 72 hours 16 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する急性毒性試験 No. 2006-生73 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 48 hours 36 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する急性毒性試験 No. 2006-生73 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality LC0 96 hours 4 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する急性毒性試験 No. 2006-生73 2008 2024/02/08
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours 3.4 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Schubauer-Berigan, M.K., Dierkes, J.R. Monson, P.D. and Ankley, G.T. pH-dependent toxicity of Cd, Cu, Ni, Pb and Zn to Ceriodaphnia dubia, Pimephales promelas, Hyalella azteca and Lumbriculus variegates. Environ.Toxicol.Chem. 1993 2018/03/22
魚類 Lepomis macrochirus (Bluegill) LC50 96 hours 5.18 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Pickering, Q.H. and Henderson, C. The acute toxicity of some heavy metals to different Species of warm water fishes. Proc.19th Ind.Waste Conf., Purdue University, West Lafayette, IN:578-591; Int.J.Air Water Pollut. 1964 2018/03/22
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours >4 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Schubauer-Berigan, M.K., Dierkes, J.R. Monson, P.D. and Ankley, G.T. pH-dependent toxicity of Cd, Cu, Ni, Pb and Zn to Ceriodaphnia dubia, Pimephales promelas, Hyalella azteca and Lumbriculus variegates. Environ.Toxicol.Chem. 1993 2018/03/22
魚類 Menidia menidia (Atlantic silverside) LC50 96 hours 7.96 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Gentile, S. and Cardin J. Unpublished laboratory data. U.S.EPA, Narragansett, RI 1982 2018/03/22
魚類 Carassius auratus (Goldfish) LC50 96 hours 9.82 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Pickering, Q.H. and Henderson, C. The acute toxicity of some heavy metals to different Species of warm water fishes Proc.19th Ind.Waste Conf., Purdue University, West Lafayette, IN:578-591; Int.J.Air Water Pollut. 1964 2018/03/22
魚類 Lepomis macrochirus (Bluegill) LC50 96 hours 37 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Bentley, R.E., Heitmuller, T. Sleight III, B.H. and Parrish, P.R. Acute toxicity of nickel to bluegill (Lepomis macrochirus), Rainbow Trout (Salmo gairdneri), and Pink Shrimp (Penaeus duorarum) U.S.EPA, Criteria Branch, WA-6-99-1414-B, Washington, D.C. 1975 2018/03/22
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours 8.1 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Nebeker, A.V., Savonen, C. and Stevens, D.G. Sensitivity of rainbow trout early life stages to nickel chloride Environ.Toxicol.Chem. 1985 2018/03/22
魚類 Poecilia reticulata (Guppy) LC50 96 hours 9.65 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Anderson, P.D. and Weber, L.J. Toxic response as a quantitative function of body size Toxicol.Appl.Pharmacol. 1975 2018/03/22
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours 4 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Tarzwell, C.M. and Henderson, C. Toxicity of less common metals to fishes Ind.Wastes 1960 2018/03/22
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours 25 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Pickering, Q.H. Chronic toxicity of nickel to the fathead minnow J.Water Pollut.Control Fed. 1974 2018/03/22
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours 3.1 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Schubauer-Berigan, M.K., Dierkes, J.R. Monson, P.D. and Ankley, G.T. pH-dependent toxicity of Cd, Cu, Ni, Pb and Zn to Ceriodaphnia dubia, Pimephales promelas, Hyalella azteca and Lumbriculus variegates. Environ.Toxicol.Chem. 1993 2018/03/22
魚類 Carassius auratus (Goldfish) LC50 7 days 2.14 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Birge, W.J. Aquatic toxicology of trace elements of coal and fly ash In: Thorp, J.H.and Gibbons, J.W. (Eds.), Dep.Energy Symp.Ser., Energy and Environmental Stress in Aquatic Systems, Augusta, GA 1978 2018/03/22
魚類 Oryzias latipes (Japanese medaka) LC50 72 hours 16 mg/L 塩化ニッケル（無水物） 11 Japan チャレンジプログラム 2018/03/14
魚類 Cyprinus carpio (Carp) LC50 96 hours 16 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Rao, T.S., Rao, M.S. and Prasad, S.B.S. Median tolerance limits of some chemicals to the fresh water fish "Cyprinus carpio". Indian J.Environ.Health 1975 2018/03/22
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours 24 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Tarzwell, C.M. and Henderson, C. Toxicity of less common metals to fishes Ind.Wastes 1960 2018/03/22
魚類 Pimephales promelas (Fathead minnow) mortality and terata and length NOEC 32 days 0.057 mg/L Ni 12 ECHA Information on Registered Substances 1 Birge, W.J., J.A. Black, J.F. Hobson, A.G. Westerman, and T.M. Short Toxicological studies on aquatic contaminants originating from coal production and utilization: The induction of tolerance to silver in laboratory populations of fish and the chronic toxicity of nickel to fish early life stages. Water Resources Research Institute. Kentucky University, Lexington, KY. Research Report No. 151. 1984 2018/01/30
魚類 Pimephales promelas (Fathead minnow) mortality and terata LOEC 32 days 0.12 mg/L Ni 12 ECHA Information on Registered Substances 1 Birge, W.J., J.A. Black, J.F. Hobson, A.G. Westerman, and T.M. Short Toxicological studies on aquatic contaminants originating from coal production and utilization: The induction of tolerance to silver in laboratory populations of fish and the chronic toxicity of nickel to fish early life stages. Water Resources Research Institute. Kentucky University, Lexington, KY. Research Report No. 151. 1984 2018/01/30
魚類 Pimephales promelas (Fathead minnow) survival and growth NOEC 7 days >16 mg/L 12 ECHA Information on Registered Substances 3 Kszos, L.A., A.J. Stewart, and P.A. Taylor An evaluation of nickel toxicity to Ceriodaphnia dubia and Daphnia magna in a contaminated stream and in laboratory tests Environmental Toxicology and Chemistry 1992 2018/01/30
魚類 Pimephales promelas (Fathead minnow) survival and growth LOEC 7 days >16 mg/L 12 ECHA Information on Registered Substances 3 Kszos, L.A., A.J. Stewart, and P.A. Taylor An evaluation of nickel toxicity to Ceriodaphnia dubia and Daphnia magna in a contaminated stream and in laboratory tests Environmental Toxicology and Chemistry 1992 2018/01/30
魚類 Oryzias latipes (Japanese medaka) ふ化所要日数、累積死亡率、毒性症状、体長・体重、摂餌量 NOEC 43 days 1.1 mg/L 11 Japan チャレンジプログラム 2018/03/17
魚類 Oryzias latipes (Japanese medaka) 発生時の胚の累積死亡率 NOEC 43 days 11 mg/L 11 Japan チャレンジプログラム 2018/03/09
魚類 Oryzias latipes (Japanese medaka) ふ化所要日数 NOEC 43 days 11 mg/L 11 Japan チャレンジプログラム 2018/03/14
魚類 Oryzias latipes (Japanese medaka) 発生時の胚の累積死亡率 LC50 43 days >11 mg/L 11 Japan チャレンジプログラム 2018/03/14
魚類 Oryzias latipes (Japanese medaka) Remaining of feeding NOEC 43 days 1.1 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) 暴露終了時の稚魚の形態異常 LOEC 43 days 11 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Dry Weight LOEC 43 days 2.3 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Abnormal behavior, Abnormal appearance NOEC 43 days 2.3 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) ふ化所要日数 LOEC 43 days >11 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Fresh Weight NOEC 43 days 1.1 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 43 days >11 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Hatching, Mortality, Toxic Symptoms, Total Length and Weight, Remaining of feeding NOEC 43 days 1.1 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 43 days >11 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) 発生時の胚の累積死亡率 NOEC 43 days 11 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) 発生時の胚の累積死亡率 LC50 43 days >11 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 208 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Total Length and Weight, Remaining of feeding LOEC 43 days 2.3 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Abnormal behavior, Abnormal appearance LOEC 43 days 4.8 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality LOEC 43 days 11 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) 発生時の胚の累積死亡率 LOEC 43 days >11 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) ふ化所要日数 NOEC 43 days 11 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Dry Weight NOEC 43 days 1.1 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Fresh Weight LOEC 43 days 2.3 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Remaining of feeding LOEC 43 days 2.3 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Total length NOEC 43 days 1.1 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) 暴露終了時の稚魚の形態異常 NOEC 43 days 4.8 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality NOEC 43 days 4.8 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Total length LOEC 43 days 2.3 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality LOEC 43 days 11 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality NOEC 43 days 4.8 mg/L ○ ○ 1 日本環境省　生態リスク初期評価 環境省 最終報告書　塩化ニッケルのヒメダカ（Oryzias latipes）に対する初期生活段階毒性試験 No. 2006-生74 2008 2024/02/08
魚類 Oncorhynchus mykiss (Rainbow trout) 成長 NOEC 75 days 0.035 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Nebeker, A.V., Savonen, C. and Stevens, D.G. Sensitivity of rainbow trout early life stages to nickel chloride Environ.Toxicol.Chem. 1985 2018/03/22
魚類 Oncorhynchus mykiss (Rainbow trout) 成長 NOEC 52 days 0.134 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Nebeker, A.V., Savonen, C. and Stevens, D.G. Sensitivity of rainbow trout early life stages to nickel chloride Environ.Toxicol.Chem. 1985 2018/03/22
魚類 Oryzias latipes (Japanese medaka) 全長、体重、摂餌量 LOEC 43 days 2.3 mg/L 11 Japan チャレンジプログラム 2018/03/14
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 28 days 0.05 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Birge, W.J. Aquatic toxicology of trace elements of coal and fly ash In: Thorp, J.H.and Gibbons, J.W. (Eds.), Dep.Energy Symp.Ser., Energy and Environmental Stress in Aquatic Systems, Augusta, GA 1978 2018/03/22
魚類 Oncorhynchus mykiss (Rainbow trout) 成長 LC50 38 days 1.4 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Nebeker, A.V., Savonen, C. and Stevens, D.G. Sensitivity of rainbow trout early life stages to nickel chloride Environ.Toxicol.Chem. 1985 2018/03/22
魚類 Oncorhynchus mykiss (Rainbow trout) 成長 NOEC 38 days 0.134 mg/L mg Ni/L 8 NITE 化学物質の初期リスク評価書 Nebeker, A.V., Savonen, C. and Stevens, D.G. Sensitivity of rainbow trout early life stages to nickel chloride Environ.Toxicol.Chem. 1985 2018/03/22
魚類 Oryzias latipes (Japanese medaka) ふ化所要日数 LOEC 43 days >11 mg/L 11 Japan チャレンジプログラム 2018/03/14
魚類 Oryzias latipes (Japanese medaka) 発生時の胚の累積死亡率 LOEC 43 days >11 mg/L 11 Japan チャレンジプログラム 2018/03/14