生態影響に係る有害性情報


CAS登録番号 CAS RN ® ： 80-05-7
官報公示整理番号　METI No. ： 4-123
物質名 test material ： ４，４’－プロパン－２，２－ジイルジフェノール　／4,4'-Propane-2,2-diyldiphenol
水溶解度 water solubility ： 120mg/L (推計値 estimated)
LogKow ： 3.32 (実測値 measured)
備考 remarks ：
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書） / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし　4:情報が少なく評価不能
日本環境省　化学物質の環境リスク評価（生態リスク初期評価） A：試験は信頼できる　B：試験は条件付きで信頼できる　C：試験の信頼性は低い　D：信頼性の判定不可　E：信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり　Supplemental:条件付きで信頼性あり　Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり：○
なし：×		 情報源 情報源による
信頼性評価**		 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value		 exposure
duration
unit		 toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material		 original work type original work
reliability rank		 author title referenced journal publication year Information
update date
藻類 Pseudokirchneriella subcapitata Growth EC50 4 days 2700 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Alexander,H.C., D.C. Dill, L.W. Smith, P.D.
Guiney, and P. Dorn		 Bisphenol A: Acute Aquatic Toxicity Environ. Toxicol. Chem.7(1): 19-26 1988 2016/03/25
藻類 Scenedesmus subspicatus Population NOEC >=250000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Nendza,M., and A. Wenzel Discriminating Toxicant Classes by Mode of Action
1. (Eco)toxicity Profiles		 Environ. Sci. Pollut. Res.13(3): 192-203 2006 2016/03/25
藻類 Pseudokirchneriella subcapitata Population EC50 4 days 3100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Alexander,H.C., D.C. Dill, L.W. Smith, P.D.
Guiney, and P. Dorn		 Bisphenol A: Acute Aquatic Toxicity Environ. Toxicol. Chem.7(1): 19-26 1988 2016/03/25
藻類 Selenastrum capricornutum Growth EC50 96 hours 3.1 mg/L 9 ECETOC Aquatic Toxicity, EAT Alexander ea 88 2016/02/08
藻類 Selenastrum capricornutum Growth EC50 96 hours 2.73 mg/L 9 ECETOC Aquatic Toxicity, EAT Alexander ea 88 2016/02/08
藻類 Selenastrum capricornutum Growth LOEC 96 hours 1.99 mg/L 9 ECETOC Aquatic Toxicity, EAT Alexander ea 88 2016/02/08
藻類 Selenastrum capricornutum Growth NOEC 96 hours 1.17 mg/L 9 ECETOC Aquatic Toxicity, EAT Alexander ea 88 2016/02/08
藻類 Selenastrum capricornutum Growth NOEC 96 hours 1.17 mg/L 9 ECETOC Aquatic Toxicity, EAT Alexander ea 88 2016/02/08
藻類 Selenastrum capricornutum Growth LOEC 96 hours 1.99 mg/L 9 ECETOC Aquatic Toxicity, EAT Alexander ea 88 2016/02/08
甲殻類 Ceriodaphnia dubia Reproduction IC50 7 days >2000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Cho,E.A. Bioturbation as a Novel Method to Characterize
the Toxicity of Aquatic Sediment		 Ph.D. Thesis, North Carolina State University,
Raleigh, NC:153 p.		 2005 2016/03/25
甲殻類 Daphnia magna Growth NOEC 21 days 6900 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Biochemical NOEC 2 days 10000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Mortality 21 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brennan,S.J., C.A. Brougham, J.J. Roche, and A.M.
Fogarty		 Multi-generational Effects of Four Selected
Environmental Oestrogens on Daphnia magna		 Chemosphere64:49-55 2006 2016/03/25
甲殻類 Ceriodaphnia dubia Reproduction IC25 3922 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Tatarazako,N., Y. Takao, K. Kishi, N. Onikura, K.
Arizono, and T. Iguchi		 Styrene Dimers and Trimers Affect Reproduction of
Daphnid (Ceriodaphnia dubia)		 Chemosphere48(6): 597-601 2002 2016/03/25
甲殻類 Daphnia magna Biochemical NOEC 2 days 10000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Physiology LOEC 2 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mansilha,C., P. Silva, S. Rocha, P. Gameiro, V.
Domingues, C. Pinho, and I.M.P.L.V.O. Ferreira		 Bisphenol A Migration from Plastic Materials:
Direct Insight of Ecotoxicity in Daphnia magna		 Environ. Sci. Pollut. Res.20(9): 6007-6018 2013 2016/03/25
甲殻類 Daphnia magna Reproduction NOEC 21 days 3000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mansilha,C., P. Silva, S. Rocha, P. Gameiro, V.
Domingues, C. Pinho, and I.M.P.L.V.O. Ferreira		 Bisphenol A Migration from Plastic Materials:
Direct Insight of Ecotoxicity in Daphnia magna		 Environ. Sci. Pollut. Res.20(9): 6007-6018 2013 2016/03/25
甲殻類 Daphnia magna Reproduction LOEC 21 days 1730 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Biochemical LOEC 21 days 13800 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Mortality 21 days 400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brennan,S.J., C.A. Brougham, J.J. Roche, and A.M.
Fogarty		 Multi-generational Effects of Four Selected
Environmental Oestrogens on Daphnia magna		 Chemosphere64:49-55 2006 2016/03/25
甲殻類 Daphnia magna Biochemical LOEC 2 days 20000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Physiology EC50 1 days 8570 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brennan,S.J., C.A. Brougham, J.J. Roche, and A.M.
Fogarty		 Multi-generational Effects of Four Selected
Environmental Oestrogens on Daphnia magna		 Chemosphere64:49-55 2006 2016/03/25
甲殻類 Daphnia magna Mortality NOEC 1 days 30 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Park,S.Y., and J. Choi Genotoxic Effects of Nonylphenol and Bisphenol A
Exposure in Aquatic Biomonitoring Species:
Freshwater Crustacean, Daphnia magna, and
Aquatic Midge, Chironomus riparius		 Bull. Environ. Contam. Toxicol.83(4): 463-468 2009 2016/03/25
甲殻類 Daphnia magna Cellular Effects NOEC 1 days 0.3 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Park,S.Y., and J. Choi Genotoxic Effects of Nonylphenol and Bisphenol A
Exposure in Aquatic Biomonitoring Species:
Freshwater Crustacean, Daphnia magna, and
Aquatic Midge, Chironomus riparius		 Bull. Environ. Contam. Toxicol.83(4): 463-468 2009 2016/03/25
甲殻類 Daphnia magna Growth LOEC 21 days 13800 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Physiology NOEC 2 days 20000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Mortality LC50 2 days 12800 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hirano,M., H. Ishibashi, N. Matsumura, Y. Nagao,
N. Watanabe, A. Watanabe, N. Onikura, K. Kishi,
and K. Arizono		 Acute Toxicity Responses of Two Crustaceans,
Americamysis bahia and Daphnia magna, to
Endocrine Disrupters		 J. Health Sci.50(1): 97-100 2004 2016/03/25
甲殻類 Daphnia magna Physiology EC50 1 days 12500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Plahuta,M., T. Tisler, M.J. Toman, and A. Pintar Efficiency of Advanced Oxidation Processes in
Lowering Bisphenol A Toxicity and Oestrogenic
Activity in Aqueous Samples		 Arh. Hig. Rada Toksikol.65(1): 77-87 2014 2016/03/25
甲殻類 Daphnia magna Physiology 1 days 20000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Plahuta,M., T. Tisler, M.J. Toman, and A. Pintar Efficiency of Advanced Oxidation Processes in
Lowering Bisphenol A Toxicity and Oestrogenic
Activity in Aqueous Samples		 Arh. Hig. Rada Toksikol.65(1): 77-87 2014 2016/03/25
甲殻類 Daphnia magna Physiology EC50 2 days 20500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Growth EC50 1 days >10500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brennan,S.J., C.A. Brougham, J.J. Roche, and A.M.
Fogarty		 Multi-generational Effects of Four Selected
Environmental Oestrogens on Daphnia magna		 Chemosphere64:49-55 2006 2016/03/25
甲殻類 Daphnia magna Reproduction LOEC 21 days 3450 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Growth 21 days 200～1000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brennan,S.J., C.A. Brougham, J.J. Roche, and A.M.
Fogarty		 Multi-generational Effects of Four Selected
Environmental Oestrogens on Daphnia magna		 Chemosphere64:49-55 2006 2016/03/25
甲殻類 Daphnia magna Biochemical LOEC 1 days 0.3 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Park,S.Y., and J. Choi Genotoxic Effects of Nonylphenol and Bisphenol A
Exposure in Aquatic Biomonitoring Species:
Freshwater Crustacean, Daphnia magna, and
Aquatic Midge, Chironomus riparius		 Bull. Environ. Contam. Toxicol.83(4): 463-468 2009 2016/03/25
甲殻類 Daphnia magna Growth NOEC 1 days 30 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Park,S.Y., and J. Choi Genotoxic Effects of Nonylphenol and Bisphenol A
Exposure in Aquatic Biomonitoring Species:
Freshwater Crustacean, Daphnia magna, and
Aquatic Midge, Chironomus riparius		 Bull. Environ. Contam. Toxicol.83(4): 463-468 2009 2016/03/25
甲殻類 Daphnia magna Reproduction NOEC 21 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brennan,S.J., C.A. Brougham, J.J. Roche, and A.M.
Fogarty		 Multi-generational Effects of Four Selected
Environmental Oestrogens on Daphnia magna		 Chemosphere64:49-55 2006 2016/03/25
甲殻類 Daphnia magna Physiology EC50 1 days 15500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Alexander,H.C., D.C. Dill, L.W. Smith, P.D.
Guiney, and P. Dorn		 Bisphenol A: Acute Aquatic Toxicity Environ. Toxicol. Chem.7(1): 19-26 1988 2016/03/25
甲殻類 Daphnia magna Reproduction NOEC 21 days 860 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Physiology EC50 1 days 352.5 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Ha,M.H., and J. Choi Effects of Environmental Contaminants on
Hemoglobin Gene Expression in Daphnia magna: A
Potential Biomarker for Freshwater
Quality Monitoring		 Arch. Environ. Contam. Toxicol.57(2): 330-337 2009 2016/03/25
甲殻類 Daphnia magna Reproduction LOEC 21 days 13800 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Cellular Effects 1 days 0.3～30 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Ha,M.H., and J. Choi Effects of Environmental Contaminants on
Hemoglobin Gene Expression in Daphnia magna: A
Potential Biomarker for Freshwater
Quality Monitoring		 Arch. Environ. Contam. Toxicol.57(2): 330-337 2009 2016/03/25
甲殻類 Daphnia magna Biochemical NOEC 21 days 6900 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Biochemical LOEC 21 days 13800 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Cellular Effects NOEC 1 days 30 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Ha,M.H., and J. Choi Effects of Environmental Contaminants on
Hemoglobin Gene Expression in Daphnia magna: A
Potential Biomarker for Freshwater
Quality Monitoring		 Arch. Environ. Contam. Toxicol.57(2): 330-337 2009 2016/03/25
甲殻類 Daphnia magna Reproduction NOEC 21 days 30 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Ha,M.H., and J. Choi Effects of Environmental Contaminants on
Hemoglobin Gene Expression in Daphnia magna: A
Potential Biomarker for Freshwater
Quality Monitoring		 Arch. Environ. Contam. Toxicol.57(2): 330-337 2009 2016/03/25
甲殻類 Daphnia magna Cellular Effects NOEC 1 days 0.3 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Ha,M.H., and J. Choi Effects of Environmental Contaminants on
Hemoglobin Gene Expression in Daphnia magna: A
Potential Biomarker for Freshwater
Quality Monitoring		 Arch. Environ. Contam. Toxicol.57(2): 330-337 2009 2016/03/25
甲殻類 Daphnia magna Biochemical NOEC 1 days 30 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Park,S.Y., and J. Choi Genotoxic Effects of Nonylphenol and Bisphenol A
Exposure in Aquatic Biomonitoring Species:
Freshwater Crustacean, Daphnia magna, and
Aquatic Midge, Chironomus riparius		 Bull. Environ. Contam. Toxicol.83(4): 463-468 2009 2016/03/25
甲殻類 Ceriodaphnia dubia Reproduction NOEC 940 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Tatarazako,N., Y. Takao, K. Kishi, N. Onikura, K.
Arizono, and T. Iguchi		 Styrene Dimers and Trimers Affect Reproduction of
Daphnid (Ceriodaphnia dubia)		 Chemosphere48(6): 597-601 2002 2016/03/25
甲殻類 Daphnia magna Mortality LC50 21 days 806 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brennan,S.J., C.A. Brougham, J.J. Roche, and A.M.
Fogarty		 Multi-generational Effects of Four Selected
Environmental Oestrogens on Daphnia magna		 Chemosphere64:49-55 2006 2016/03/25
甲殻類 Daphnia magna Reproduction NOEC 21 days 1730 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Reproduction NOEC 21 days 800 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brennan,S.J., C.A. Brougham, J.J. Roche, and A.M.
Fogarty		 Multi-generational Effects of Four Selected
Environmental Oestrogens on Daphnia magna		 Chemosphere64:49-55 2006 2016/03/25
甲殻類 Daphnia magna Cellular Effects 1 days 0.3～30 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Ha,M.H., and J. Choi Effects of Environmental Contaminants on
Hemoglobin Gene Expression in Daphnia magna: A
Potential Biomarker for Freshwater
Quality Monitoring		 Arch. Environ. Contam. Toxicol.57(2): 330-337 2009 2016/03/25
甲殻類 Daphnia magna Growth 21 days 316～3160 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Caspers,N. No Estrogenic Effects of Biphenol A in Daphnia
magna Straus		 Bull. Environ. Contam. Toxicol.61:143-148 1998 2016/03/25
甲殻類 Daphnia magna Mortality 21 days 860～13800 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Physiology EC50 2 days 9940 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mansilha,C., P. Silva, S. Rocha, P. Gameiro, V.
Domingues, C. Pinho, and I.M.P.L.V.O. Ferreira		 Bisphenol A Migration from Plastic Materials:
Direct Insight of Ecotoxicity in Daphnia magna		 Environ. Sci. Pollut. Res.20(9): 6007-6018 2013 2016/03/25
甲殻類 Daphnia magna Biochemical LOEC 21 days 1730 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Biochemical LOEC 2 days 20000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Growth EC50 2 days >10500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brennan,S.J., C.A. Brougham, J.J. Roche, and A.M.
Fogarty		 Multi-generational Effects of Four Selected
Environmental Oestrogens on Daphnia magna		 Chemosphere64:49-55 2006 2016/03/25
甲殻類 Daphnia magna Physiology EC50 2 days 7750 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brennan,S.J., C.A. Brougham, J.J. Roche, and A.M.
Fogarty		 Multi-generational Effects of Four Selected
Environmental Oestrogens on Daphnia magna		 Chemosphere64:49-55 2006 2016/03/25
甲殻類 Daphnia magna Physiology NOEC 2 days 3000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mansilha,C., P. Silva, S. Rocha, P. Gameiro, V.
Domingues, C. Pinho, and I.M.P.L.V.O. Ferreira		 Bisphenol A Migration from Plastic Materials:
Direct Insight of Ecotoxicity in Daphnia magna		 Environ. Sci. Pollut. Res.20(9): 6007-6018 2013 2016/03/25
甲殻類 Daphnia magna Cellular Effects LOEC 1 days 3 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Ha,M.H., and J. Choi Effects of Environmental Contaminants on
Hemoglobin Gene Expression in Daphnia magna: A
Potential Biomarker for Freshwater
Quality Monitoring		 Arch. Environ. Contam. Toxicol.57(2): 330-337 2009 2016/03/25
甲殻類 Daphnia magna Mortality 2 days 100～20000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Reproduction NOEC 21 days 6900 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Cellular Effects 3 days 10000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hannas,B.R., Y.H. Wang, S. Thomson, G. Kwon, H.
Li, and G.A. LeBlanc		 Regulation and Dysregulation of Vitellogenin mRNA
Accumulation in Daphnids (Daphnia magna)		 Aquat. Toxicol.101(2): 351-357 2011 2016/03/25
甲殻類 Daphnia magna Physiology EC50 1 days 21000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Growth NOEC 1 days 30 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Park,S.Y., and J. Choi Genotoxic Effects of Nonylphenol and Bisphenol A
Exposure in Aquatic Biomonitoring Species:
Freshwater Crustacean, Daphnia magna, and
Aquatic Midge, Chironomus riparius		 Bull. Environ. Contam. Toxicol.83(4): 463-468 2009 2016/03/25
甲殻類 Daphnia magna Biochemical NOEC 21 days 6900 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Mortality 14 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mansilha,C., P. Silva, S. Rocha, P. Gameiro, V.
Domingues, C. Pinho, and I.M.P.L.V.O. Ferreira		 Bisphenol A Migration from Plastic Materials:
Direct Insight of Ecotoxicity in Daphnia magna		 Environ. Sci. Pollut. Res.20(9): 6007-6018 2013 2016/03/25
甲殻類 Daphnia magna Physiology EC50 2 days 10200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Alexander,H.C., D.C. Dill, L.W. Smith, P.D.
Guiney, and P. Dorn		 Bisphenol A: Acute Aquatic Toxicity Environ. Toxicol. Chem.7(1): 19-26 1988 2016/03/25
甲殻類 Daphnia magna Biochemical NOEC 21 days 860 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Cellular Effects LOEC 1 days 3 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Park,S.Y., and J. Choi Genotoxic Effects of Nonylphenol and Bisphenol A
Exposure in Aquatic Biomonitoring Species:
Freshwater Crustacean, Daphnia magna, and
Aquatic Midge, Chironomus riparius		 Bull. Environ. Contam. Toxicol.83(4): 463-468 2009 2016/03/25
甲殻類 Daphnia magna Physiology EC50 1 days 13800 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Ceriodaphnia dubia Reproduction LOEC 1880 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Tatarazako,N., Y. Takao, K. Kishi, N. Onikura, K.
Arizono, and T. Iguchi		 Styrene Dimers and Trimers Affect Reproduction of
Daphnid (Ceriodaphnia dubia)		 Chemosphere48(6): 597-601 2002 2016/03/25
甲殻類 Daphnia magna Biochemical LOEC 2 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Jemec,A., T. Tisler, B. Erjavec, and A. Pintar Antioxidant Responses and Whole-Organism Changes
in Daphnia magna Acutely and Chronically Exposed
to Endocrine Disruptor Bisphenol A		 Ecotoxicol. Environ. Saf.86:213-218 2012 2016/03/25
甲殻類 Daphnia magna Lethal EC50 24 hours 15.5 mg/L 9 ECETOC Aquatic Toxicity, EAT Alexander ea 88 2016/02/08
甲殻類 Daphnia magna Lethal EC50 48 hours 10.2 mg/L 9 ECETOC Aquatic Toxicity, EAT Alexander ea 88 2016/02/08
甲殻類 Daphnia magna Lethal LOEC 24 hours 6.97 mg/L 9 ECETOC Aquatic Toxicity, EAT Alexander ea 88 2016/02/08
甲殻類 Daphnia magna Lethal LOEC 48 hours 4.97 mg/L 9 ECETOC Aquatic Toxicity, EAT Alexander ea 88 2016/02/08
甲殻類 Daphnia magna Lethal NOEC 24 hours 4.11 mg/L 9 ECETOC Aquatic Toxicity, EAT Alexander ea 88 2016/02/08
甲殻類 Daphnia magna Lethal NOEC 48 hours 4.11 mg/L 9 ECETOC Aquatic Toxicity, EAT Alexander ea 88 2016/02/08
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 164 days 160 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 44 days 200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior NOEC 21 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior NOEC 18 hours 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 7 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 4 days 6030 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chan,W.K., and K.M. Chan Disruption of the Hypothalamic-Pituitary-Thyroid
Axis in Zebrafish Embryo-Larvae Following
Waterborne Exposure to BDE-47, TBBPA and BPA		 Aquat. Toxicol.108:106-111 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 7 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 2 days 1000 pM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Moffatt,L.T., K.D. Fagan-Solis, E.P. Browne, and
K.F. Arcaro		 Vitellogenin and 11beta Hydroxylase mRNA
Expression in Male Japanese Medaka (Oryzias
latipes) Exposed in a Short Term
Laboratory Assay to Low Levels
of Three Estrogenic
Contaminants		 Environ. Indicators J.:16 p. 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 21 days 120～130 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brian,J.V., C.A. Harris, M. Scholze, A.
Kortenkamp, P. Booy, M. Lamoree, G. Pojana, N.
Jonkers, A. Marcomini, and J.P. S		 Evidence of Estrogenic Mixture Effects on the
Reproductive Performance of Fish		 Environ. Sci. Technol.41(1): 337-344 2007 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 30 days 0.25～0.61 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects 6 days 5～500 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,C., J.G. Na, K.C. Lee, and K. Park Choriogenin mRNA Induction in Male Medaka,
Oryzias latipes as a Biomarker of Endocrine
Disruption		 Aquat. Toxicol.61(3-4): 233-241 2002 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 30 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth 10～200 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Metcalfe,C.D., T.L. Metcalfe, Y. Kiparissis, B.G.
Koenig, C. Khan, R.J. Hughes, T.R. Croley, R.E.
March, and T. Potter		 Estrogenic Potency of Chemicals Detected in
Sewage Treatment Plant Effluents as Determined
by In Vivo Assays with Japanese Medaka
(Oryzias latipes)		 Environ. Toxicol. Chem.20(2): 297-308 2001 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical LOEC 14 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Ekman,D.R., P.C. Hartig, M. Cardon, D.M. Skelton,
Q. Teng, E.J. Durhan, K.M. Jensen, M.D. Kahl, D.
L. Villeneuve, L.E.,Jr		 Metabolite Profiling and a Transcriptional
Activation Assay Provide Direct Evidence of
Androgen Receptor Antagonism by
Bisphenol A in Fish		 Environ. Sci. Technol.46(17): 9673-9680 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 90 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Accumulation 2 days 1～100 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Saili,K.S., M.M. Corvi, D.N. Weber, A.U. Patel, S.
R. Das, J. Przybyla, K.A. Anderson, and R.L.
Tanguay		 Neurodevelopmental Low-Dose Bisphenol A Exposure
Leads to Early Life-Stage Hyperactivity and
Learning Deficits in Adult Zebrafish		 Toxicology291(1-3): 83-92 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 60 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 44 days 6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction NOEC 90 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 30 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 90 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical LOEC 4 days 81 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Reproduction 10～200 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Metcalfe,C.D., T.L. Metcalfe, Y. Kiparissis, B.G.
Koenig, C. Khan, R.J. Hughes, T.R. Croley, R.E.
March, and T. Potter		 Estrogenic Potency of Chemicals Detected in
Sewage Treatment Plant Effluents as Determined
by In Vivo Assays with Japanese Medaka
(Oryzias latipes)		 Environ. Toxicol. Chem.20(2): 297-308 2001 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Accumulation 0.43 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lindholst,C., S.N. Pedersen, and P. Bjerregaard Uptake, Metabolism and Excretion of Bisphenol A
in the Rainbow Trout (Oncorhynchus mykiss)		 Aquat. Toxicol.55(1-2): 75-84 2001 2016/03/25
魚類 Carassius auratus (Goldfish) Biochemical NOEC 30 days 0.72～4.5 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 90 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality 21 days 40～1000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Van den Belt,K., R. Verheyen, and H. Witters Comparison of Vitellogenin Responses in Zebrafish
and Rainbow Trout Following Exposure to
Environmental Estrogens		 Ecotoxicol. Environ. Saf.56(2): 271-281 2003 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 14 days 30 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brian,J.V., C.A. Harris, M. Scholze, T. Backhaus,
P. Booy, M. Lamoree, G. Pojana, N. Jonkers, T.
Runnalls, A. Bonfa, A.		 Accurate Prediction of the Response of Freshwater
Fish to a Mixture of Estrogenic Chemicals		 Environ. Health Perspect.113(6): 721-728 2005 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 44 days 6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Growth LOEC 316 days 400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality 5 days 1～100 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Saili,K.S., M.M. Corvi, D.N. Weber, A.U. Patel, S.
R. Das, J. Przybyla, K.A. Anderson, and R.L.
Tanguay		 Neurodevelopmental Low-Dose Bisphenol A Exposure
Leads to Early Life-Stage Hyperactivity and
Learning Deficits in Adult Zebrafish		 Toxicology291(1-3): 83-92 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 43 days 1280 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 60 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 7 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality NOEC 36 days 579 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Physiology NOEC 21 days 500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 4 days 3930 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chan,W.K., and K.M. Chan Disruption of the Hypothalamic-Pituitary-Thyroid
Axis in Zebrafish Embryo-Larvae Following
Waterborne Exposure to BDE-47, TBBPA and BPA		 Aquat. Toxicol.108:106-111 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 14 days 11.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Ankley,G.T., K.M. Jensen, M.D. Kahl, E.J. Durhan,
E.A. Makynen, J.E. Cavallin, D. Martinovic, L.C.
Wehmas, N.D. Mueller,		 Use of Chemical Mixtures to Differentiate
Mechanisms of Endocrine Action in a Small Fish
Model		 Aquat. Toxicol.99(3): 389-396 2010 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 3 days 2000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Pelayo,S., E. Oliveira, B. Thienpont, P.J. Babin,
D. Raldua, M. Andre, and B. Pina		 Triiodothyronine-Induced Changes in the Zebrafish
Transcriptome During the Eleutheroembryonic
Stage: Implications for Bisphenol A
Developmental Toxicity		 Aquat. Toxicol.110:114-122 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 21 days 280～300 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brian,J.V., C.A. Harris, M. Scholze, A.
Kortenkamp, P. Booy, M. Lamoree, G. Pojana, N.
Jonkers, A. Marcomini, and J.P. S		 Evidence of Estrogenic Mixture Effects on the
Reproductive Performance of Fish		 Environ. Sci. Technol.41(1): 337-344 2007 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 1 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 4700 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Alexander,H.C., D.C. Dill, L.W. Smith, P.D.
Guiney, and P. Dorn		 Bisphenol A: Acute Aquatic Toxicity Environ. Toxicol. Chem.7(1): 19-26 1988 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality NOEC 2.96 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Cypher,A.D., J.R. Ickes, and B. Bagatto Bisphenol A Alters the Cardiovascular Response to
Hypoxia in Danio rerio Embryos		 Comp. Biochem. Physiol. C Toxicol. Pharmacol.
174/175:39-45		 2015 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 185 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 4 days 0.061 mM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Fei,X.C., C. Song, and H.W. Gao Transmembrane Transports of Acrylamide and
Bisphenol A and Effects on Development of
Zebrafish (Danio rerio)		 J. Hazard. Mater.184(1-3): 81-88 2010 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior LOEC 21 hours 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 2 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction NOEC 90 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical LOEC 164 days 160 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 60 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects 21 days 593～3804 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kang,I.J., H. Yokota, Y. Oshima, Y. Tsuruda, T.
Oe, N. Imada, H. Tadokoro, and T. Honjo		 Effects of Bisphenol A on the Reproduction of
Japanese Medaka (Oryzias latipes)		 Environ. Toxicol. Chem.21(11): 2394-2400 2002 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 431 days 16 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Accumulation 8 hours 0.2 mM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Fei,X.C., C. Song, and H.W. Gao Transmembrane Transports of Acrylamide and
Bisphenol A and Effects on Development of
Zebrafish (Danio rerio)		 J. Hazard. Mater.184(1-3): 81-88 2010 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 60 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 8 hours 8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Yamaguchi,A., H. Ishibashi, S. Kohra, K. Arizono,
and N. Tominaga		 Short-Term Effects of Endocrine-Disrupting
Chemicals on the Expression of Estrogen-
Responsive Genes in Male Medaka (Oryzias
latipes)		 Aquat. Toxicol.72(3): 239-249 2005 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 30 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 20 days 0.25～0.61 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Gasterosteus aculeatus (Three-spined stickleback) Growth LOEC 165 days 53.62～93.6 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 De Kermoysan,G., S. Joachim, P. Baudoin, M.
Lonjaret, C. Tebby, F. Lesaulnier, F. Lestremau,
C. Chatellier, Z. Akrour, E		 Effects of Bisphenol A on Different Trophic
Levels in a Lotic Experimental Ecosystem		 Aquat. Toxicol.144-145:186-198 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 44 days 200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth LOEC 2 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 10 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Physiology LOEC 2 days 10 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 2 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 3.75 days 1 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 7 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Biochemical NOEC 10 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 21 days 500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 3 days 8300 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kashiwada,S., H. Ishikawa, N. Miyamoto, Y.
Ohnishi, and Y. Magara		 Fish Test for Endocrine-Disruption and Estimation
of Water Quality of Japanese Rivers		 Water Res.36(8): 2161-2166 2002 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 30 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 444 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 4 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,O., A. Takesono, M. Tada, C.R. Tyler, and T.
Kudoh		 Biosensor Zebrafish Provide New Insights into
Potential Health Effects of Environmental
Estrogens		 Environ. Health Perspect.120(7): 990-996 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality NOEC 600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 1 days 4700 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Alexander,H.C., D.C. Dill, L.W. Smith, P.D.
Guiney, and P. Dorn		 Bisphenol A: Acute Aquatic Toxicity Environ. Toxicol. Chem.7(1): 19-26 1988 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior NOEC 13 hours 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Gasterosteus aculeatus (Three-spined stickleback) Population NOEC 165 days 53.62～93.6 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 De Kermoysan,G., S. Joachim, P. Baudoin, M.
Lonjaret, C. Tebby, F. Lesaulnier, F. Lestremau,
C. Chatellier, Z. Akrour, E		 Effects of Bisphenol A on Different Trophic
Levels in a Lotic Experimental Ecosystem		 Aquat. Toxicol.144-145:186-198 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 36 days 579 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 4 days 81 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth LOEC 2 days 1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth NOEC 2 days 10 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 2 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Gasterosteus aculeatus (Three-spined stickleback) Growth NOEC 165 days 53.62～93.6 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 De Kermoysan,G., S. Joachim, P. Baudoin, M.
Lonjaret, C. Tebby, F. Lesaulnier, F. Lestremau,
C. Chatellier, Z. Akrour, E		 Effects of Bisphenol A on Different Trophic
Levels in a Lotic Experimental Ecosystem		 Aquat. Toxicol.144-145:186-198 2013 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Biochemical 50 mg/kg bdwt 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Christiansen,L.B., K.L. Pedersen, S.N. Pedersen,
B. Korsgaard, and P. Bjerregaard		 In Vivo Comparison of Xenoestrogens Using Rainbow
Trout Vitellogenin Induction as a Screening
System		 Environ. Toxicol. Chem.19(7): 1867-1874 2000 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 164 days 13.4 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 15 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Biochemical 21 days 2432～3804 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kang,I.J., H. Yokota, Y. Oshima, Y. Tsuruda, T.
Oe, N. Imada, H. Tadokoro, and T. Honjo		 Effects of Bisphenol A on the Reproduction of
Japanese Medaka (Oryzias latipes)		 Environ. Toxicol. Chem.21(11): 2394-2400 2002 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 15 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth LOEC 5.9 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Metcalfe,C.D., T.L. Metcalfe, Y. Kiparissis, B.G.
Koenig, C. Khan, R.J. Hughes, T.R. Croley, R.E.
March, and T. Potter		 Estrogenic Potency of Chemicals Detected in
Sewage Treatment Plant Effluents as Determined
by In Vivo Assays with Japanese Medaka
(Oryzias latipes)		 Environ. Toxicol. Chem.20(2): 297-308 2001 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth NOEC 4 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 60 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 2 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 60 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 1 days 0.0001 mM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Gentilcore,D., I. Porreca, F. Rizzo, E. Ganbaatar,
E. Carchia, M. Mallardo, M. De Felice, and C.
Ambrosino		 Bisphenol A Interferes with Thyroid Specific Gene
Expression		 Toxicology304:21-31 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Biochemical 14 days 20～2500 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., J. Zha, and Z. Wang Interactions Between Estrogenic Chemicals in
Binary Mixtures Investigated Using Vitellogenin
Induction and Factorial Analysis		 Chemosphere75:410-415 2009 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Biochemical 0.1～100 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Tabata,A., S. Kashiwada, Y. Ohnishi, H. Ishikawa,
N. Miyamoto, M. Itoh, and Y. Magara		 Estrogenic Influences of Estradiol-17beta, p-
Nonylphenol and bis-Phenol-A on Japanese Medaka
(Oryzias latipes) at Detected
Environmental Concentrations		 Water Sci. Technol.43(2): 109-116 2001 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects 21 days 20～500 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 15 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 3.75 days 5 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth LOEC 4 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality LOEC 200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 4 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 15 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 444 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 60 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Biochemical LOEC 7 days 500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sakuyama,H., Y. Endo, K. Fujimoto, and Y. Hatano Oxidative Degradation of Alkylphenols by
Horseradish Peroxidase		 J. Biosci. Bioeng.96(3): 227-231 2003 2016/03/25
魚類 Danio rerio (Zebrafish) Growth LOEC 2.96 days 250 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Cypher,A.D., J.R. Ickes, and B. Bagatto Bisphenol A Alters the Cardiovascular Response to
Hypoxia in Danio rerio Embryos		 Comp. Biochem. Physiol. C Toxicol. Pharmacol.
174/175:39-45		 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 5 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M. Microbial Transformations of Tetrabromobisphenol
A and Its Metabolites, and Their Impact on
Toxicity to the Developing Zebrafish (Danio
rerio) Embryo		 Ph.D.Thesis, Rutgers, The State University of New
Jersey, New Brunswick, NJ:191 p.		 2010 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 90 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 30 days 400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Growth LOEC 316 days 400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 21 days 280～300 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brian,J.V., C.A. Harris, M. Scholze, A.
Kortenkamp, P. Booy, M. Lamoree, G. Pojana, N.
Jonkers, A. Marcomini, and J.P. S		 Evidence of Estrogenic Mixture Effects on the
Reproductive Performance of Fish		 Environ. Sci. Technol.41(1): 337-344 2007 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction NOEC 20 days 0.25～0.61 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction NOEC 90 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Biochemical LOEC 30 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Mortality 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Gasterosteus aculeatus (Three-spined stickleback) Population NOEC 165 days 53.62～93.6 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 De Kermoysan,G., S. Joachim, P. Baudoin, M.
Lonjaret, C. Tebby, F. Lesaulnier, F. Lestremau,
C. Chatellier, Z. Akrour, E		 Effects of Bisphenol A on Different Trophic
Levels in a Lotic Experimental Ecosystem		 Aquat. Toxicol.144-145:186-198 2013 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Growth 9 days 50 mg/kg bdwt 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Christiansen,L.B., K.L. Pedersen, B. Korsgaard,
and P. Bjerregaard		 Estrogenicity of Xenobiotics in Rainbow Trout
(Oncorhynchus mykiss) Using In Vivo Synthesis of
Vitellogenin as a Biomarker		 Mar. Environ. Res.46(1-5): 137-140 1998 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 90 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Biochemical NOEC 10 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction NOEC 20 days 0.25～0.61 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Physiology LOEC 5 days 3420 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R.
Cooper, and L.A. White		 Embryonic Exposure to Tetrabromobisphenol A and
Its Metabolites, Bisphenol A and
Tetrabromobisphenol A Dimethyl Ether Disrupts
Normal Zebrafish (Danio
rerio) Development and
Matrix
Metalloproteinase Expression		 Aquat. Toxicol.100(3): 255-262 2010 2016/03/25
魚類 Danio rerio (Zebrafish) Growth LOEC 7 days 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R.
Cooper, and L.A. White		 Embryonic Exposure to Tetrabromobisphenol A and
Its Metabolites, Bisphenol A and
Tetrabromobisphenol A Dimethyl Ether Disrupts
Normal Zebrafish (Danio
rerio) Development and
Matrix
Metalloproteinase Expression		 Aquat. Toxicol.100(3): 255-262 2010 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 44 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 60 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical LOEC 431 days 160 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 164 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 7 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Reproduction LOEC 14 days 1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Molina,A.M., A.J. Lora, A. Blanco, J.G. Monterde,
N. Ayala, and R. Moyano		 Endocrine-Active Compound Evaluation: Qualitative
and Quantitative Histomorphological Assessment
of Zebrafish Gonads After Bisphenol-A Exposure		 Ecotoxicol. Environ. Saf.88:155-162 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 3 days 4000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Pelayo,S., E. Oliveira, B. Thienpont, P.J. Babin,
D. Raldua, M. Andre, and B. Pina		 Triiodothyronine-Induced Changes in the Zebrafish
Transcriptome During the Eleutheroembryonic
Stage: Implications for Bisphenol A
Developmental Toxicity		 Aquat. Toxicol.110:114-122 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction 164 days >160～<640 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 6.83 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Danio rerio (Zebrafish) No Group Code 5 days 80 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Padilla,S., D. Corum, B. Padnos, D.L. Hunter, A.
Beam, K.A. Houck, N. Sipes, N. Kleinstreuer, T.
Knudsen, D.J. Dix, and		 Zebrafish Developmental Screening of the ToxCast
Phase I Chemical Library		 Reprod. Toxicol.33(2): 174-187 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction 20 days 0.25～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 20 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 44 days 6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior NOEC 12 hours 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 21 hours 1 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 185 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction NOEC 30 days 0.25～0.61 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 6.83 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Physiology NOEC 7 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., T. Van Es, K.R. Cooper, L.A.
White, and M.M. Haggblom		 Microbially Mediated O-Methylation of Bisphenol A
Results in Metabolites with Increased Toxicity
to the Developing Zebrafish (Danio rerio)
Embryo		 Environ. Sci. Technol.45(15): 6567-6574 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Physiology NOEC 21 days 500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 164 days 1280 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 3.75 days 5 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 4 days 0.97 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 4 days 81 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Growth LOEC 316 days 400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality 164 days >0.1～<1280 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality 164 days >100～<160 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth NOEC 10.6 days 600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Carassius auratus (Goldfish) Biochemical NOEC 10 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 3.75 days 1 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality LOEC 200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 44 days 600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 2 days 8500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., A. Wichmann, R. Kriehuber, C.
Schafers, R. Fischer, and M. Fenske		 Transcriptome Alterations in Zebrafish Embryos
After Exposure to Environmental Estrogens and
Anti-Androgens can Reveal Endocrine
Disruption		 Reprod. Toxicol.42:210-223 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality 5 days 73 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Saili,K.S., M.M. Corvi, D.N. Weber, A.U. Patel, S.
R. Das, J. Przybyla, K.A. Anderson, and R.L.
Tanguay		 Neurodevelopmental Low-Dose Bisphenol A Exposure
Leads to Early Life-Stage Hyperactivity and
Learning Deficits in Adult Zebrafish		 Toxicology291(1-3): 83-92 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 3 days 5100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kashiwada,S., H. Ishikawa, N. Miyamoto, Y.
Ohnishi, and Y. Magara		 Fish Test for Endocrine-Disruption and Estimation
of Water Quality of Japanese Rivers		 Water Res.36(8): 2161-2166 2002 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 2 days 8500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., A. Wichmann, R. Kriehuber, C.
Schafers, R. Fischer, and M. Fenske		 Transcriptome Alterations in Zebrafish Embryos
After Exposure to Environmental Estrogens and
Anti-Androgens can Reveal Endocrine
Disruption		 Reprod. Toxicol.42:210-223 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 4 days 800 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chan,W.K., and K.M. Chan Disruption of the Hypothalamic-Pituitary-Thyroid
Axis in Zebrafish Embryo-Larvae Following
Waterborne Exposure to BDE-47, TBBPA and BPA		 Aquat. Toxicol.108:106-111 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 60 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects 44 days 6～600 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects 44 days 6～600 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality 164 days >160～<640 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEL 4 days 2620 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chow,W.S., W.K.L. Chan, and K.M. Chan Toxicity Assessment and Vitellogenin Expression
in Zebrafish (Danio rerio) Embryos and Larvae
Acutely Exposed to Bisphenol A, Endosulfan,
Heptachlor, Methoxychlor and
Tetrabromobisphenol A		 J. Appl. Toxicol.33:670-678 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 21 hours 1 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality EC50 4 days 5246 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chow,W.S., W.K.L. Chan, and K.M. Chan Toxicity Assessment and Vitellogenin Expression
in Zebrafish (Danio rerio) Embryos and Larvae
Acutely Exposed to Bisphenol A, Endosulfan,
Heptachlor, Methoxychlor and
Tetrabromobisphenol A		 J. Appl. Toxicol.33:670-678 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality 10～400 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth EC10 7 days 7000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., X. Zhang, M. Hecker, C. Schafers, R.
Fischer, and M. Fenske		 Species-Specific Considerations in Using the Fish
Embryo Test as an Alternative to Identify
Endocrine Disruption		 Aquat. Toxicol.155:62-72 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 71 days 1280 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction NOEC 90 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 21 days 120～130 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brian,J.V., C.A. Harris, M. Scholze, A.
Kortenkamp, P. Booy, M. Lamoree, G. Pojana, N.
Jonkers, A. Marcomini, and J.P. S		 Evidence of Estrogenic Mixture Effects on the
Reproductive Performance of Fish		 Environ. Sci. Technol.41(1): 337-344 2007 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 44 days 60 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 15 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) No Group Code EC50 5 days 46.2207 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Padilla,S., D. Corum, B. Padnos, D.L. Hunter, A.
Beam, K.A. Houck, N. Sipes, N. Kleinstreuer, T.
Knudsen, D.J. Dix, and		 Zebrafish Developmental Screening of the ToxCast
Phase I Chemical Library		 Reprod. Toxicol.33(2): 174-187 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 4 days 8041 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chow,W.S., W.K.L. Chan, and K.M. Chan Toxicity Assessment and Vitellogenin Expression
in Zebrafish (Danio rerio) Embryos and Larvae
Acutely Exposed to Bisphenol A, Endosulfan,
Heptachlor, Methoxychlor and
Tetrabromobisphenol A		 J. Appl. Toxicol.33:670-678 2013 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 44 days 600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction 20 days 0.25～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction LOEC 21 days 280～300 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brian,J.V., C.A. Harris, M. Scholze, A.
Kortenkamp, P. Booy, M. Lamoree, G. Pojana, N.
Jonkers, A. Marcomini, and J.P. S		 Evidence of Estrogenic Mixture Effects on the
Reproductive Performance of Fish		 Environ. Sci. Technol.41(1): 337-344 2007 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 44 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 2 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 7 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 60 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Growth 180 days 10～400 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Growth 180 days 10～400 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 431 days 16 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Reproduction 14 days 250～4000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kang,I.J., H. Yokota, Y. Oshima, Y. Tsuruda, T.
Oe, N. Imada, H. Tadokoro, and T. Honjo		 Effects of Bisphenol A on the Reproduction of
Japanese Medaka (Oryzias latipes)		 Environ. Toxicol. Chem.21(11): 2394-2400 2002 2016/03/25
魚類 Gasterosteus aculeatus (Three-spined stickleback) Population NOEC 165 days 53.62～93.6 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 De Kermoysan,G., S. Joachim, P. Baudoin, M.
Lonjaret, C. Tebby, F. Lesaulnier, F. Lestremau,
C. Chatellier, Z. Akrour, E		 Effects of Bisphenol A on Different Trophic
Levels in a Lotic Experimental Ecosystem		 Aquat. Toxicol.144-145:186-198 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 71 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 295 days 16 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 90 days 400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 5.08 days 17.5 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R.
Cooper, and L.A. White		 Embryonic Exposure to Tetrabromobisphenol A and
Its Metabolites, Bisphenol A and
Tetrabromobisphenol A Dimethyl Ether Disrupts
Normal Zebrafish (Danio
rerio) Development and
Matrix
Metalloproteinase Expression		 Aquat. Toxicol.100(3): 255-262 2010 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 2 days 4700 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Alexander,H.C., D.C. Dill, L.W. Smith, P.D.
Guiney, and P. Dorn		 Bisphenol A: Acute Aquatic Toxicity Environ. Toxicol. Chem.7(1): 19-26 1988 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEL 4 days 3930 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chow,W.S., W.K.L. Chan, and K.M. Chan Toxicity Assessment and Vitellogenin Expression
in Zebrafish (Danio rerio) Embryos and Larvae
Acutely Exposed to Bisphenol A, Endosulfan,
Heptachlor, Methoxychlor and
Tetrabromobisphenol A		 J. Appl. Toxicol.33:670-678 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior LOEC 4.75 days 5 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 2 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 164 days 1280 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 1.83 days 0.07 mM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Selderslaghs,I.W.T., R. Blust, and H.E. Witters Feasibility Study of the Zebrafish Assay as an
Alternative Method to Screen for Developmental
Toxicity and Embryotoxicity Using a Training
Set of 27 Compounds		 Reprod. Toxicol.33(2): 142-154 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 44 days 6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Physiology LOEC 2.96 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Cypher,A.D., J.R. Ickes, and B. Bagatto Bisphenol A Alters the Cardiovascular Response to
Hypoxia in Danio rerio Embryos		 Comp. Biochem. Physiol. C Toxicol. Pharmacol.
174/175:39-45		 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Growth 180 days 10～400 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 30 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Biochemical LOEC 30 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Gasterosteus aculeatus (Three-spined stickleback) Growth NOEC 165 days 53.62～93.6 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 De Kermoysan,G., S. Joachim, P. Baudoin, M.
Lonjaret, C. Tebby, F. Lesaulnier, F. Lestremau,
C. Chatellier, Z. Akrour, E		 Effects of Bisphenol A on Different Trophic
Levels in a Lotic Experimental Ecosystem		 Aquat. Toxicol.144-145:186-198 2013 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 44 days 200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Physiology NOEC 5 days 2300 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R.
Cooper, and L.A. White		 Embryonic Exposure to Tetrabromobisphenol A and
Its Metabolites, Bisphenol A and
Tetrabromobisphenol A Dimethyl Ether Disrupts
Normal Zebrafish (Danio
rerio) Development and
Matrix
Metalloproteinase Expression		 Aquat. Toxicol.100(3): 255-262 2010 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction NOEC 10 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Reproduction LOEC 14 days 1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Molina,A.M., A.J. Lora, A. Blanco, J.G. Monterde,
N. Ayala, and R. Moyano		 Endocrine-Active Compound Evaluation: Qualitative
and Quantitative Histomorphological Assessment
of Zebrafish Gonads After Bisphenol-A Exposure		 Ecotoxicol. Environ. Saf.88:155-162 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Reproduction LOEC 7 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., T. Van Es, K.R. Cooper, L.A.
White, and M.M. Haggblom		 Microbially Mediated O-Methylation of Bisphenol A
Results in Metabolites with Increased Toxicity
to the Developing Zebrafish (Danio rerio)
Embryo		 Environ. Sci. Technol.45(15): 6567-6574 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Warner,K.E. Environmental Estrogens and Skeletal Development
Disruption in the Fathead Minnow, a Teleost
Model of Vertebrate Developmental Toxicity		 Ph.D.Thesis, Oregon State University, Corvallis,
OR:105 p.		 2006 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior NOEC 20 hours 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality NOEC 5 days 2500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., T. Van Es, K.R. Cooper, L.A.
White, and M.M. Haggblom		 Microbially Mediated O-Methylation of Bisphenol A
Results in Metabolites with Increased Toxicity
to the Developing Zebrafish (Danio rerio)
Embryo		 Environ. Sci. Technol.45(15): 6567-6574 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 71 days 16 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 20 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior NOEC 14 hours 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical 4 days 4 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Vethaak,A.D., J. Lahr, S.M. Schrap, A.C. Belfroid,
G.B.J. Rijs, A. Gerritsen, J. De Boer, A.S.
Bulder, G.C.M. Grinwis, R		 An Integrated Assessment of Estrogenic
Contamination and Biological Effects in the
Aquatic Environment of the
Netherlands		 Chemosphere59(4): 511-524 2005 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 5.83 days 0.02 mM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Selderslaghs,I.W.T., R. Blust, and H.E. Witters Feasibility Study of the Zebrafish Assay as an
Alternative Method to Screen for Developmental
Toxicity and Embryotoxicity Using a Training
Set of 27 Compounds		 Reprod. Toxicol.33(2): 142-154 2012 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Biochemical 9 days 50 mg/kg bdwt 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Andersen,H.R., A.M. Andersson, S.F. Arnold, H.
Autrup, M. Barfoed, N.A. Beresford, P.
Bjerregaard, L.B. Christiansen, B.		 Comparison of Short-Term Estrogenicity Tests for
Identification of Hormone-Disrupting Chemicals		 Environ. Health Perspect.107(suppl.1): 89-108 1999 2016/03/25
魚類 Danio rerio (Zebrafish) Accumulation LOEC 14 days 1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Molina,A.M., A.J. Lora, A. Blanco, J.G. Monterde,
N. Ayala, and R. Moyano		 Endocrine-Active Compound Evaluation: Qualitative
and Quantitative Histomorphological Assessment
of Zebrafish Gonads After Bisphenol-A Exposure		 Ecotoxicol. Environ. Saf.88:155-162 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 21 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Reproduction LOEC 14 days 1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Molina,A.M., A.J. Lora, A. Blanco, J.G. Monterde,
N. Ayala, and R. Moyano		 Endocrine-Active Compound Evaluation: Qualitative
and Quantitative Histomorphological Assessment
of Zebrafish Gonads After Bisphenol-A Exposure		 Ecotoxicol. Environ. Saf.88:155-162 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 21 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Warner,K.E. Environmental Estrogens and Skeletal Development
Disruption in the Fathead Minnow, a Teleost
Model of Vertebrate Developmental Toxicity		 Ph.D.Thesis, Oregon State University, Corvallis,
OR:105 p.		 2006 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality NOEC 60 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 295 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction NOEC 10 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Reproduction 21 days 593～3804 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kang,I.J., H. Yokota, Y. Oshima, Y. Tsuruda, T.
Oe, N. Imada, H. Tadokoro, and T. Honjo		 Effects of Bisphenol A on the Reproduction of
Japanese Medaka (Oryzias latipes)		 Environ. Toxicol. Chem.21(11): 2394-2400 2002 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 60 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 60 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEL 4 days 3930 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chow,W.S., W.K.L. Chan, and K.M. Chan Toxicity Assessment and Vitellogenin Expression
in Zebrafish (Danio rerio) Embryos and Larvae
Acutely Exposed to Bisphenol A, Endosulfan,
Heptachlor, Methoxychlor and
Tetrabromobisphenol A		 J. Appl. Toxicol.33:670-678 2013 2016/03/25
魚類 Gasterosteus aculeatus (Three-spined stickleback) Growth LOEC 165 days 0.47～1.72 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 De Kermoysan,G., S. Joachim, P. Baudoin, M.
Lonjaret, C. Tebby, F. Lesaulnier, F. Lestremau,
C. Chatellier, Z. Akrour, E		 Effects of Bisphenol A on Different Trophic
Levels in a Lotic Experimental Ecosystem		 Aquat. Toxicol.144-145:186-198 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 7 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) No Group Code EC10 5 days 42.648 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Padilla,S., D. Corum, B. Padnos, D.L. Hunter, A.
Beam, K.A. Houck, N. Sipes, N. Kleinstreuer, T.
Knudsen, D.J. Dix, and		 Zebrafish Developmental Screening of the ToxCast
Phase I Chemical Library		 Reprod. Toxicol.33(2): 174-187 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Growth LOEC 5 days >20～<30 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Saili,K.S., M.M. Corvi, D.N. Weber, A.U. Patel, S.
R. Das, J. Przybyla, K.A. Anderson, and R.L.
Tanguay		 Neurodevelopmental Low-Dose Bisphenol A Exposure
Leads to Early Life-Stage Hyperactivity and
Learning Deficits in Adult Zebrafish		 Toxicology291(1-3): 83-92 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 30 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Metcalfe,C.D., T.L. Metcalfe, Y. Kiparissis, B.G.
Koenig, C. Khan, R.J. Hughes, T.R. Croley, R.E.
March, and T. Potter		 Estrogenic Potency of Chemicals Detected in
Sewage Treatment Plant Effluents as Determined
by In Vivo Assays with Japanese Medaka
(Oryzias latipes)		 Environ. Toxicol. Chem.20(2): 297-308 2001 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction 10 days 0.25～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 4 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 71 days 1280 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 71 days 1280 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 1.75 days 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 10 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 3 days 5100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Tabata,A., S. Kashiwada, Y. Ohnishi, H. Ishikawa,
N. Miyamoto, M. Itoh, and Y. Magara		 Estrogenic Influences of Estradiol-17beta, p-
Nonylphenol and bis-Phenol-A on Japanese Medaka
(Oryzias latipes) at Detected
Environmental Concentrations		 Water Sci. Technol.43(2): 109-116 2001 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 43 days >1280 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction LOEC 21 days 280～300 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brian,J.V., C.A. Harris, M. Scholze, A.
Kortenkamp, P. Booy, M. Lamoree, G. Pojana, N.
Jonkers, A. Marcomini, and J.P. S		 Evidence of Estrogenic Mixture Effects on the
Reproductive Performance of Fish		 Environ. Sci. Technol.41(1): 337-344 2007 2016/03/25
魚類 Danio rerio (Zebrafish) Growth 166 days 10～400 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 4 days 6030 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chan,W.K., and K.M. Chan Disruption of the Hypothalamic-Pituitary-Thyroid
Axis in Zebrafish Embryo-Larvae Following
Waterborne Exposure to BDE-47, TBBPA and BPA		 Aquat. Toxicol.108:106-111 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 44 days 6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 43 days 1280 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 60 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 431 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 2 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical LOEC 431 days 160 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality EC20 4 days 75 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Min,J., S.K. Lee, and M.B. Gu Effects of Endocrine Disrupting Chemicals on
Distinct Expression Patterns of Estrogen
Receptor, Cytochrome P450 Aromatase and
p53 Genes in Oryzias latipes
Liver		 J. Biochem. Mol. Toxicol.17(5): 272-277 2003 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth EC20 7 days 8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., X. Zhang, M. Hecker, C. Schafers, R.
Fischer, and M. Fenske		 Species-Specific Considerations in Using the Fish
Embryo Test as an Alternative to Identify
Endocrine Disruption		 Aquat. Toxicol.155:62-72 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Physiology NOEC 2.96 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Cypher,A.D., J.R. Ickes, and B. Bagatto Bisphenol A Alters the Cardiovascular Response to
Hypoxia in Danio rerio Embryos		 Comp. Biochem. Physiol. C Toxicol. Pharmacol.
174/175:39-45		 2015 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 44 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 44 days 200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 2 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 2.75 days 5 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 2 days 8500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., A. Wichmann, R. Kriehuber, C.
Schafers, R. Fischer, and M. Fenske		 Transcriptome Alterations in Zebrafish Embryos
After Exposure to Environmental Estrogens and
Anti-Androgens can Reveal Endocrine
Disruption		 Reprod. Toxicol.42:210-223 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 14 days 11.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Ankley,G.T., K.M. Jensen, M.D. Kahl, E.J. Durhan,
E.A. Makynen, J.E. Cavallin, D. Martinovic, L.C.
Wehmas, N.D. Mueller,		 Use of Chemical Mixtures to Differentiate
Mechanisms of Endocrine Action in a Small Fish
Model		 Aquat. Toxicol.99(3): 389-396 2010 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 2 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 185 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 21 days 500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior NOEC 21 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 3 days 4000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Pelayo,S., E. Oliveira, B. Thienpont, P.J. Babin,
D. Raldua, M. Andre, and B. Pina		 Triiodothyronine-Induced Changes in the Zebrafish
Transcriptome During the Eleutheroembryonic
Stage: Implications for Bisphenol A
Developmental Toxicity		 Aquat. Toxicol.110:114-122 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 4 days 579 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Population 0.1～100 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Tabata,A., S. Kashiwada, Y. Ohnishi, H. Ishikawa,
N. Miyamoto, M. Itoh, and Y. Magara		 Estrogenic Influences of Estradiol-17beta, p-
Nonylphenol and bis-Phenol-A on Japanese Medaka
(Oryzias latipes) at Detected
Environmental Concentrations		 Water Sci. Technol.43(2): 109-116 2001 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction 164 days >0.1～<1280 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 30 days 400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEL 4 days 4020 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chow,W.S., W.K.L. Chan, and K.M. Chan Toxicity Assessment and Vitellogenin Expression
in Zebrafish (Danio rerio) Embryos and Larvae
Acutely Exposed to Bisphenol A, Endosulfan,
Heptachlor, Methoxychlor and
Tetrabromobisphenol A		 J. Appl. Toxicol.33:670-678 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 155 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth 50 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Metcalfe,C.D., T.L. Metcalfe, Y. Kiparissis, B.G.
Koenig, C. Khan, R.J. Hughes, T.R. Croley, R.E.
March, and T. Potter		 Estrogenic Potency of Chemicals Detected in
Sewage Treatment Plant Effluents as Determined
by In Vivo Assays with Japanese Medaka
(Oryzias latipes)		 Environ. Toxicol. Chem.20(2): 297-308 2001 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 164 days 52.8 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical LOEC 4 days 7.5 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality 14 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Molina,A.M., A.J. Lora, A. Blanco, J.G. Monterde,
N. Ayala, and R. Moyano		 Endocrine-Active Compound Evaluation: Qualitative
and Quantitative Histomorphological Assessment
of Zebrafish Gonads After Bisphenol-A Exposure		 Ecotoxicol. Environ. Saf.88:155-162 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 10 days 0.25～0.61 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality 14 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Ekman,D.R., P.C. Hartig, M. Cardon, D.M. Skelton,
Q. Teng, E.J. Durhan, K.M. Jensen, M.D. Kahl, D.
L. Villeneuve, L.E.,Jr		 Metabolite Profiling and a Transcriptional
Activation Assay Provide Direct Evidence of
Androgen Receptor Antagonism by
Bisphenol A in Fish		 Environ. Sci. Technol.46(17): 9673-9680 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 164 days >1280 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 431 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 21 days 500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 3.75 days 1 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects 5 days 1140～3420 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R.
Cooper, and L.A. White		 Embryonic Exposure to Tetrabromobisphenol A and
Its Metabolites, Bisphenol A and
Tetrabromobisphenol A Dimethyl Ether Disrupts
Normal Zebrafish (Danio
rerio) Development and
Matrix
Metalloproteinase Expression		 Aquat. Toxicol.100(3): 255-262 2010 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 164 days 130 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 15 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Physiology LOEC 2.96 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Cypher,A.D., J.R. Ickes, and B. Bagatto Bisphenol A Alters the Cardiovascular Response to
Hypoxia in Danio rerio Embryos		 Comp. Biochem. Physiol. C Toxicol. Pharmacol.
174/175:39-45		 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 4 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,O., A. Takesono, M. Tada, C.R. Tyler, and T.
Kudoh		 Biosensor Zebrafish Provide New Insights into
Potential Health Effects of Environmental
Estrogens		 Environ. Health Perspect.120(7): 990-996 2012 2016/03/25
魚類 Gasterosteus aculeatus (Three-spined stickleback) Growth NOEC 165 days 53.62～93.6 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 De Kermoysan,G., S. Joachim, P. Baudoin, M.
Lonjaret, C. Tebby, F. Lesaulnier, F. Lestremau,
C. Chatellier, Z. Akrour, E		 Effects of Bisphenol A on Different Trophic
Levels in a Lotic Experimental Ecosystem		 Aquat. Toxicol.144-145:186-198 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior NOEC 21 hours 5 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 316 days 200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 7 days 10000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., T. Van Es, K.R. Cooper, L.A.
White, and M.M. Haggblom		 Microbially Mediated O-Methylation of Bisphenol A
Results in Metabolites with Increased Toxicity
to the Developing Zebrafish (Danio rerio)
Embryo		 Environ. Sci. Technol.45(15): 6567-6574 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 30 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 14 days 11.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Ankley,G.T., K.M. Jensen, M.D. Kahl, E.J. Durhan,
E.A. Makynen, J.E. Cavallin, D. Martinovic, L.C.
Wehmas, N.D. Mueller,		 Use of Chemical Mixtures to Differentiate
Mechanisms of Endocrine Action in a Small Fish
Model		 Aquat. Toxicol.99(3): 389-396 2010 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 3 days 4700 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Alexander,H.C., D.C. Dill, L.W. Smith, P.D.
Guiney, and P. Dorn		 Bisphenol A: Acute Aquatic Toxicity Environ. Toxicol. Chem.7(1): 19-26 1988 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 90 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects 5.08 days 25 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R.
Cooper, and L.A. White		 Embryonic Exposure to Tetrabromobisphenol A and
Its Metabolites, Bisphenol A and
Tetrabromobisphenol A Dimethyl Ether Disrupts
Normal Zebrafish (Danio
rerio) Development and
Matrix
Metalloproteinase Expression		 Aquat. Toxicol.100(3): 255-262 2010 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 14 days 102 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Ankley,G.T., K.M. Jensen, M.D. Kahl, E.J. Durhan,
E.A. Makynen, J.E. Cavallin, D. Martinovic, L.C.
Wehmas, N.D. Mueller,		 Use of Chemical Mixtures to Differentiate
Mechanisms of Endocrine Action in a Small Fish
Model		 Aquat. Toxicol.99(3): 389-396 2010 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 60 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Biochemical 35 mg/kg bdwt 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lindholst,C., S.N. Pedersen, and P. Bjerregaard Uptake, Metabolism and Excretion of Bisphenol A
in the Rainbow Trout (Oncorhynchus mykiss)		 Aquat. Toxicol.55(1-2): 75-84 2001 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality NOEC 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Warner,K.E., and J.J. Jenkins Effects of 17alpha-Ethinylestradiol and Bisphenol
A on Vertebral Development in the Fathead Minnow
(Pimephales promelas)		 Environ. Toxicol. Chem.26(4): 732-737 2007 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 7 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 4 days 3930 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chan,W.K., and K.M. Chan Disruption of the Hypothalamic-Pituitary-Thyroid
Axis in Zebrafish Embryo-Larvae Following
Waterborne Exposure to BDE-47, TBBPA and BPA		 Aquat. Toxicol.108:106-111 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 3.75 days 1 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Warner,K.E. Environmental Estrogens and Skeletal Development
Disruption in the Fathead Minnow, a Teleost
Model of Vertebrate Developmental Toxicity		 Ph.D.Thesis, Oregon State University, Corvallis,
OR:105 p.		 2006 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 15 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects 6 days 5～500 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,C., J.G. Na, K.C. Lee, and K. Park Choriogenin mRNA Induction in Male Medaka,
Oryzias latipes as a Biomarker of Endocrine
Disruption		 Aquat. Toxicol.61(3-4): 233-241 2002 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 21 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Van den Belt,K., R. Verheyen, and H. Witters Comparison of Vitellogenin Responses in Zebrafish
and Rainbow Trout Following Exposure to
Environmental Estrogens		 Ecotoxicol. Environ. Saf.56(2): 271-281 2003 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Population NOEC 44 days 600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction LOEC 164 days 130 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 1 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Biochemical NOEC 10 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 164 days 1280 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEL 3 days 10 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Suzawa,M., and H.A. Ingraham The Herbicide Atrazine Activates Endocrine Gene
Networks via Non-Steroidal NR5A Nuclear
Receptors in Fish and Mammalian Cells		 PLoS One3(5): 11 p. 2008 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 2.83 days 0.07 mM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Selderslaghs,I.W.T., R. Blust, and H.E. Witters Feasibility Study of the Zebrafish Assay as an
Alternative Method to Screen for Developmental
Toxicity and Embryotoxicity Using a Training
Set of 27 Compounds		 Reprod. Toxicol.33(2): 142-154 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 60 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 30 days 400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 6.83 days 1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior LOEC 4.75 days 1 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 6.83 days 1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 6.83 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior NOEC 4.75 days 1 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 10 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality 5 days 10000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., T. Van Es, K.R. Cooper, L.A.
White, and M.M. Haggblom		 Microbially Mediated O-Methylation of Bisphenol A
Results in Metabolites with Increased Toxicity
to the Developing Zebrafish (Danio rerio)
Embryo		 Environ. Sci. Technol.45(15): 6567-6574 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 6.83 days 0.1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 4 days 1000 pM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Moffatt,L.T., K.D. Fagan-Solis, E.P. Browne, and
K.F. Arcaro		 Vitellogenin and 11beta Hydroxylase mRNA
Expression in Male Japanese Medaka (Oryzias
latipes) Exposed in a Short Term
Laboratory Assay to Low Levels
of Three Estrogenic
Contaminants		 Environ. Indicators J.:16 p. 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 5 days 2500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M. Microbial Transformations of Tetrabromobisphenol
A and Its Metabolites, and Their Impact on
Toxicity to the Developing Zebrafish (Danio
rerio) Embryo		 Ph.D.Thesis, Rutgers, The State University of New
Jersey, New Brunswick, NJ:191 p.		 2010 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 7 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 30 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 5 days 1140 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R.
Cooper, and L.A. White		 Embryonic Exposure to Tetrabromobisphenol A and
Its Metabolites, Bisphenol A and
Tetrabromobisphenol A Dimethyl Ether Disrupts
Normal Zebrafish (Danio
rerio) Development and
Matrix
Metalloproteinase Expression		 Aquat. Toxicol.100(3): 255-262 2010 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 3 days 4000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Pelayo,S., E. Oliveira, B. Thienpont, P.J. Babin,
D. Raldua, M. Andre, and B. Pina		 Triiodothyronine-Induced Changes in the Zebrafish
Transcriptome During the Eleutheroembryonic
Stage: Implications for Bisphenol A
Developmental Toxicity		 Aquat. Toxicol.110:114-122 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality 4 days 6030 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chan,W.K., and K.M. Chan Disruption of the Hypothalamic-Pituitary-Thyroid
Axis in Zebrafish Embryo-Larvae Following
Waterborne Exposure to BDE-47, TBBPA and BPA		 Aquat. Toxicol.108:106-111 2012 2016/03/25
魚類 Poecilia reticulata (Guppy) Mortality 30 days 500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kinnberg,K., and G. Toft Effects of Estrogenic and Antiandrogenic
Compounds on the Testis Structure of the Adult
Guppy (Poecilia reticulata)		 Ecotoxicol. Environ. Saf.54(1): 16-24 2003 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 1 days 0.0001 mM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Gentilcore,D., I. Porreca, F. Rizzo, E. Ganbaatar,
E. Carchia, M. Mallardo, M. De Felice, and C.
Ambrosino		 Bisphenol A Interferes with Thyroid Specific Gene
Expression		 Toxicology304:21-31 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 7 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 30 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Physiology NOEC 21 days 500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Physiology LOEC 21 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 15 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 414 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 4 days 81 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 44 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 3 days 4000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Pelayo,S., E. Oliveira, B. Thienpont, P.J. Babin,
D. Raldua, M. Andre, and B. Pina		 Triiodothyronine-Induced Changes in the Zebrafish
Transcriptome During the Eleutheroembryonic
Stage: Implications for Bisphenol A
Developmental Toxicity		 Aquat. Toxicol.110:114-122 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior NOEC 1.75 days 5 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction NOEC 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 60 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 7 days 8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., X. Zhang, M. Hecker, C. Schafers, R.
Fischer, and M. Fenske		 Species-Specific Considerations in Using the Fish
Embryo Test as an Alternative to Identify
Endocrine Disruption		 Aquat. Toxicol.155:62-72 2014 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 7 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 1 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects 10～400 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 6.83 days 0.1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 295 days 16 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 7 days 8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., X. Zhang, M. Hecker, C. Schafers, R.
Fischer, and M. Fenske		 Species-Specific Considerations in Using the Fish
Embryo Test as an Alternative to Identify
Endocrine Disruption		 Aquat. Toxicol.155:62-72 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 6.83 days 0.1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 2.96 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Cypher,A.D., J.R. Ickes, and B. Bagatto Bisphenol A Alters the Cardiovascular Response to
Hypoxia in Danio rerio Embryos		 Comp. Biochem. Physiol. C Toxicol. Pharmacol.
174/175:39-45		 2015 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 4 days 0.97 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 6.83 days 10 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Biochemical EC50 7 days 1600 ppm 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chikae,M., R. Ikeda, Q. Hasan, Y. Morita, and E.
Tamiya		 Effect of Alkylphenols on Adult Male Medaka:
Plasma Vitellogenin Goes up to the Level of
Estrous Female		 Environ. Toxicol. Pharmacol.15(1): 33-36 2003 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 2 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 21 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 3.75 days 5 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality LOEC 4 days 1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 44 days 60 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 3 days 7500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Tabata,A., S. Kashiwada, Y. Ohnishi, H. Ishikawa,
N. Miyamoto, M. Itoh, and Y. Magara		 Estrogenic Influences of Estradiol-17beta, p-
Nonylphenol and bis-Phenol-A on Japanese Medaka
(Oryzias latipes) at Detected
Environmental Concentrations		 Water Sci. Technol.43(2): 109-116 2001 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 90 days 400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Growth 90 days 10～400 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 2.75 days 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 30 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction NOEC 10 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 30 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction LOEC 125 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 21 days 500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 1 days 0.00001 mM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Gentilcore,D., I. Porreca, F. Rizzo, E. Ganbaatar,
E. Carchia, M. Mallardo, M. De Felice, and C.
Ambrosino		 Bisphenol A Interferes with Thyroid Specific Gene
Expression		 Toxicology304:21-31 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior LOEC 21 hours 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Physiology NOEC 2.96 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Cypher,A.D., J.R. Ickes, and B. Bagatto Bisphenol A Alters the Cardiovascular Response to
Hypoxia in Danio rerio Embryos		 Comp. Biochem. Physiol. C Toxicol. Pharmacol.
174/175:39-45		 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Physiology NOEC 2.96 days 250 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Cypher,A.D., J.R. Ickes, and B. Bagatto Bisphenol A Alters the Cardiovascular Response to
Hypoxia in Danio rerio Embryos		 Comp. Biochem. Physiol. C Toxicol. Pharmacol.
174/175:39-45		 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Reproduction NOEC 6.83 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 90 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Biochemical 35 mg/kg bdwt 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lindholst,C., S.N. Pedersen, and P. Bjerregaard Uptake, Metabolism and Excretion of Bisphenol A
in the Rainbow Trout (Oncorhynchus mykiss)		 Aquat. Toxicol.55(1-2): 75-84 2001 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 14 days 102 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Ankley,G.T., K.M. Jensen, M.D. Kahl, E.J. Durhan,
E.A. Makynen, J.E. Cavallin, D. Martinovic, L.C.
Wehmas, N.D. Mueller,		 Use of Chemical Mixtures to Differentiate
Mechanisms of Endocrine Action in a Small Fish
Model		 Aquat. Toxicol.99(3): 389-396 2010 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 30 days 0.25～0.61 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction NOEC 20 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 20 days 0.25～0.61 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical LOEC 71 days 160 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 7 days 10 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R.
Cooper, and L.A. White		 Embryonic Exposure to Tetrabromobisphenol A and
Its Metabolites, Bisphenol A and
Tetrabromobisphenol A Dimethyl Ether Disrupts
Normal Zebrafish (Danio
rerio) Development and
Matrix
Metalloproteinase Expression		 Aquat. Toxicol.100(3): 255-262 2010 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality EC50 4 days 5250 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chan,W.K., and K.M. Chan Disruption of the Hypothalamic-Pituitary-Thyroid
Axis in Zebrafish Embryo-Larvae Following
Waterborne Exposure to BDE-47, TBBPA and BPA		 Aquat. Toxicol.108:106-111 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior LOEC 1.75 days 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality 0.1～100 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Tabata,A., S. Kashiwada, Y. Ohnishi, H. Ishikawa,
N. Miyamoto, M. Itoh, and Y. Magara		 Estrogenic Influences of Estradiol-17beta, p-
Nonylphenol and bis-Phenol-A on Japanese Medaka
(Oryzias latipes) at Detected
Environmental Concentrations		 Water Sci. Technol.43(2): 109-116 2001 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior LOEC 4.75 days 5 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical LOEC 164 days 52.8 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 155 days >640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior NOEC 17 hours 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 1 days 4700 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Alexander,H.C., D.C. Dill, L.W. Smith, P.D.
Guiney, and P. Dorn		 Bisphenol A: Acute Aquatic Toxicity Environ. Toxicol. Chem.7(1): 19-26 1988 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality NOEC 60 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 44 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical 4 days 0.013～81 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical 6.83 days 0.1～1000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 444 days >640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 444 days >640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical LOEC 295 days 160 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 7 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction LOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 4 days 81 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 3 days 6800 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kashiwada,S., H. Ishikawa, N. Miyamoto, Y.
Ohnishi, and Y. Magara		 Fish Test for Endocrine-Disruption and Estimation
of Water Quality of Japanese Rivers		 Water Res.36(8): 2161-2166 2002 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction NOEC 10 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior 4.75 days 1～15 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 5 days >70 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Saili,K.S., M.M. Corvi, D.N. Weber, A.U. Patel, S.
R. Das, J. Przybyla, K.A. Anderson, and R.L.
Tanguay		 Neurodevelopmental Low-Dose Bisphenol A Exposure
Leads to Early Life-Stage Hyperactivity and
Learning Deficits in Adult Zebrafish		 Toxicology291(1-3): 83-92 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 5 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., T. Van Es, K.R. Cooper, L.A.
White, and M.M. Haggblom		 Microbially Mediated O-Methylation of Bisphenol A
Results in Metabolites with Increased Toxicity
to the Developing Zebrafish (Danio rerio)
Embryo		 Environ. Sci. Technol.45(15): 6567-6574 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 4 days 7.5 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 44 days 60 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 90 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Physiology 21 days 20～500 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 30 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Biochemical NOEC 30 days 0.72～4.5 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical 90 days 10～400 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 3.75 days 1 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 414 days >640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 7 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 30 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth 164 days >0.1～<1280 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction NOEC 30 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 30 days 0.72～4.5 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 7 days 8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., X. Zhang, M. Hecker, C. Schafers, R.
Fischer, and M. Fenske		 Species-Specific Considerations in Using the Fish
Embryo Test as an Alternative to Identify
Endocrine Disruption		 Aquat. Toxicol.155:62-72 2014 2016/03/25
魚類 Gasterosteus aculeatus (Three-spined stickleback) Population NOEC 165 days 1.98～10.43 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 De Kermoysan,G., S. Joachim, P. Baudoin, M.
Lonjaret, C. Tebby, F. Lesaulnier, F. Lestremau,
C. Chatellier, Z. Akrour, E		 Effects of Bisphenol A on Different Trophic
Levels in a Lotic Experimental Ecosystem		 Aquat. Toxicol.144-145:186-198 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior NOEC 15 hours 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 3.75 days 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Growth 166 days 10～400 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Accumulation 8 hours 0.2 mM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Fei,X.C., C. Song, and H.W. Gao Transmembrane Transports of Acrylamide and
Bisphenol A and Effects on Development of
Zebrafish (Danio rerio)		 J. Hazard. Mater.184(1-3): 81-88 2010 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 7 days 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R.
Cooper, and L.A. White		 Embryonic Exposure to Tetrabromobisphenol A and
Its Metabolites, Bisphenol A and
Tetrabromobisphenol A Dimethyl Ether Disrupts
Normal Zebrafish (Danio
rerio) Development and
Matrix
Metalloproteinase Expression		 Aquat. Toxicol.100(3): 255-262 2010 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 155 days >640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Growth 4 days 0.0075～0.12 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Fei,X.C., C. Song, and H.W. Gao Transmembrane Transports of Acrylamide and
Bisphenol A and Effects on Development of
Zebrafish (Danio rerio)		 J. Hazard. Mater.184(1-3): 81-88 2010 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth 164 days >0.1～<1280 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 4 days 3930 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chan,W.K., and K.M. Chan Disruption of the Hypothalamic-Pituitary-Thyroid
Axis in Zebrafish Embryo-Larvae Following
Waterborne Exposure to BDE-47, TBBPA and BPA		 Aquat. Toxicol.108:106-111 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Biochemical 20 mg/g fd 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chikae,M., R. Ikeda, Q. Hasan, Y. Morita, and E.
Tamiya		 Effect of Alkylphenols on Adult Male Medaka:
Plasma Vitellogenin Goes up to the Level of
Estrous Female		 Environ. Toxicol. Pharmacol.15(1): 33-36 2003 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 2.96 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Cypher,A.D., J.R. Ickes, and B. Bagatto Bisphenol A Alters the Cardiovascular Response to
Hypoxia in Danio rerio Embryos		 Comp. Biochem. Physiol. C Toxicol. Pharmacol.
174/175:39-45		 2015 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical LOEC 43 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior NOEC 1.75 days 5 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical LOEC 164 days >1280 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects 14 days 1～1000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Molina,A.M., A.J. Lora, A. Blanco, J.G. Monterde,
N. Ayala, and R. Moyano		 Endocrine-Active Compound Evaluation: Qualitative
and Quantitative Histomorphological Assessment
of Zebrafish Gonads After Bisphenol-A Exposure		 Ecotoxicol. Environ. Saf.88:155-162 2013 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 7 days 8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., X. Zhang, M. Hecker, C. Schafers, R.
Fischer, and M. Fenske		 Species-Specific Considerations in Using the Fish
Embryo Test as an Alternative to Identify
Endocrine Disruption		 Aquat. Toxicol.155:62-72 2014 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth NOEC 4 days 0.1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 4 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Accumulation 8 hours 0.1～0.5 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Fei,X.C., C. Song, and H.W. Gao Transmembrane Transports of Acrylamide and
Bisphenol A and Effects on Development of
Zebrafish (Danio rerio)		 J. Hazard. Mater.184(1-3): 81-88 2010 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 44 days 600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Growth EC10 4 days 8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., X. Zhang, M. Hecker, C. Schafers, R.
Fischer, and M. Fenske		 Species-Specific Considerations in Using the Fish
Embryo Test as an Alternative to Identify
Endocrine Disruption		 Aquat. Toxicol.155:62-72 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical LOEC 4 days 7.5 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 7 days 8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., X. Zhang, M. Hecker, C. Schafers, R.
Fischer, and M. Fenske		 Species-Specific Considerations in Using the Fish
Embryo Test as an Alternative to Identify
Endocrine Disruption		 Aquat. Toxicol.155:62-72 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical LOEC 43 days >1280 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior LOEC 4.75 days 1 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior LOEC 4.75 days 1 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical 164 days >0.1～<1280 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior NOEC 21 days 500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior NOEC 19 hours 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 7 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 30 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 431 days >640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Warner,K.E., and J.J. Jenkins Effects of 17alpha-Ethinylestradiol and Bisphenol
A on Vertebral Development in the Fathead Minnow
(Pimephales promelas)		 Environ. Toxicol. Chem.26(4): 732-737 2007 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth NOEC 44 days 600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 44 days 600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 4 days 81 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects 1 days 0.00001～0.001 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Gentilcore,D., I. Porreca, F. Rizzo, E. Ganbaatar,
E. Carchia, M. Mallardo, M. De Felice, and C.
Ambrosino		 Bisphenol A Interferes with Thyroid Specific Gene
Expression		 Toxicology304:21-31 2013 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 44 days 200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 21 days 120～130 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brian,J.V., C.A. Harris, M. Scholze, A.
Kortenkamp, P. Booy, M. Lamoree, G. Pojana, N.
Jonkers, A. Marcomini, and J.P. S		 Evidence of Estrogenic Mixture Effects on the
Reproductive Performance of Fish		 Environ. Sci. Technol.41(1): 337-344 2007 2016/03/25
魚類 Danio rerio (Zebrafish) Growth 2 days 8500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., X. Zhang, M. Hecker, C. Schafers, R.
Fischer, and M. Fenske		 Species-Specific Considerations in Using the Fish
Embryo Test as an Alternative to Identify
Endocrine Disruption		 Aquat. Toxicol.155:62-72 2014 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth 7 days 8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., X. Zhang, M. Hecker, C. Schafers, R.
Fischer, and M. Fenske		 Species-Specific Considerations in Using the Fish
Embryo Test as an Alternative to Identify
Endocrine Disruption		 Aquat. Toxicol.155:62-72 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEL 4 days 6030 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chow,W.S., W.K.L. Chan, and K.M. Chan Toxicity Assessment and Vitellogenin Expression
in Zebrafish (Danio rerio) Embryos and Larvae
Acutely Exposed to Bisphenol A, Endosulfan,
Heptachlor, Methoxychlor and
Tetrabromobisphenol A		 J. Appl. Toxicol.33:670-678 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 4 days 81 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth NOEC 2 days 0.1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction >640～<1280 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 60 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 164 days 130 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Gasterosteus aculeatus (Three-spined stickleback) Growth LOEC 165 days 1.98～10.43 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 De Kermoysan,G., S. Joachim, P. Baudoin, M.
Lonjaret, C. Tebby, F. Lesaulnier, F. Lestremau,
C. Chatellier, Z. Akrour, E		 Effects of Bisphenol A on Different Trophic
Levels in a Lotic Experimental Ecosystem		 Aquat. Toxicol.144-145:186-198 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 316 days 200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Gasterosteus aculeatus (Three-spined stickleback) Population NOEC 165 days 1.98～10.43 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 De Kermoysan,G., S. Joachim, P. Baudoin, M.
Lonjaret, C. Tebby, F. Lesaulnier, F. Lestremau,
C. Chatellier, Z. Akrour, E		 Effects of Bisphenol A on Different Trophic
Levels in a Lotic Experimental Ecosystem		 Aquat. Toxicol.144-145:186-198 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Warner,K.E., and J.J. Jenkins Effects of 17alpha-Ethinylestradiol and Bisphenol
A on Vertebral Development in the Fathead Minnow
(Pimephales promelas)		 Environ. Toxicol. Chem.26(4): 732-737 2007 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 21 days 120～130 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brian,J.V., C.A. Harris, M. Scholze, A.
Kortenkamp, P. Booy, M. Lamoree, G. Pojana, N.
Jonkers, A. Marcomini, and J.P. S		 Evidence of Estrogenic Mixture Effects on the
Reproductive Performance of Fish		 Environ. Sci. Technol.41(1): 337-344 2007 2016/03/25
魚類 Carassius auratus (Goldfish) Biochemical NOEC 20 days 0.25～0.61 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction 164 days >0.1～<1280 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 7 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 384 days 16 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction 164 days >100～<160 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical 164 days >0.1～<1280 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth 0.1～100 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Tabata,A., S. Kashiwada, Y. Ohnishi, H. Ishikawa,
N. Miyamoto, M. Itoh, and Y. Magara		 Estrogenic Influences of Estradiol-17beta, p-
Nonylphenol and bis-Phenol-A on Japanese Medaka
(Oryzias latipes) at Detected
Environmental Concentrations		 Water Sci. Technol.43(2): 109-116 2001 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 2 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 60 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects 21 days 20～500 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 21 days 280～300 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brian,J.V., C.A. Harris, M. Scholze, A.
Kortenkamp, P. Booy, M. Lamoree, G. Pojana, N.
Jonkers, A. Marcomini, and J.P. S		 Evidence of Estrogenic Mixture Effects on the
Reproductive Performance of Fish		 Environ. Sci. Technol.41(1): 337-344 2007 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Reproduction 14 days 250～4000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kang,I.J., H. Yokota, Y. Oshima, Y. Tsuruda, T.
Oe, N. Imada, H. Tadokoro, and T. Honjo		 Effects of Bisphenol A on the Reproduction of
Japanese Medaka (Oryzias latipes)		 Environ. Toxicol. Chem.21(11): 2394-2400 2002 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior NOEC 4.75 days 1 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 155 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality 14 days 2500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., J. Zha, and Z. Wang Interactions Between Estrogenic Chemicals in
Binary Mixtures Investigated Using Vitellogenin
Induction and Factorial Analysis		 Chemosphere75:410-415 2009 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction NOEC 30 days 0.72～4.5 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 295 days >640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 36 days 579 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects 44 days 6～600 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality NOEC 164 days 130 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Reproduction NOEC 316 days 400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior LOEC 21 days 500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 15 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 3 days 17.5 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Pelayo,S., E. Oliveira, B. Thienpont, P.J. Babin,
D. Raldua, M. Andre, and B. Pina		 Triiodothyronine-Induced Changes in the Zebrafish
Transcriptome During the Eleutheroembryonic
Stage: Implications for Bisphenol A
Developmental Toxicity		 Aquat. Toxicol.110:114-122 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects 10～200 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Metcalfe,C.D., T.L. Metcalfe, Y. Kiparissis, B.G.
Koenig, C. Khan, R.J. Hughes, T.R. Croley, R.E.
March, and T. Potter		 Estrogenic Potency of Chemicals Detected in
Sewage Treatment Plant Effluents as Determined
by In Vivo Assays with Japanese Medaka
(Oryzias latipes)		 Environ. Toxicol. Chem.20(2): 297-308 2001 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 6.83 days 0.1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Gasterosteus aculeatus (Three-spined stickleback) Population LOEC 165 days 53.62～93.6 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 De Kermoysan,G., S. Joachim, P. Baudoin, M.
Lonjaret, C. Tebby, F. Lesaulnier, F. Lestremau,
C. Chatellier, Z. Akrour, E		 Effects of Bisphenol A on Different Trophic
Levels in a Lotic Experimental Ecosystem		 Aquat. Toxicol.144-145:186-198 2013 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Biochemical 0.43 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lindholst,C., S.N. Pedersen, and P. Bjerregaard Uptake, Metabolism and Excretion of Bisphenol A
in the Rainbow Trout (Oncorhynchus mykiss)		 Aquat. Toxicol.55(1-2): 75-84 2001 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Accumulation 35 mg/kg bdwt 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lindholst,C., S.N. Pedersen, and P. Bjerregaard Uptake, Metabolism and Excretion of Bisphenol A
in the Rainbow Trout (Oncorhynchus mykiss)		 Aquat. Toxicol.55(1-2): 75-84 2001 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 6.83 days 0.1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Physiology NOEC 5 days 3420 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R.
Cooper, and L.A. White		 Embryonic Exposure to Tetrabromobisphenol A and
Its Metabolites, Bisphenol A and
Tetrabromobisphenol A Dimethyl Ether Disrupts
Normal Zebrafish (Danio
rerio) Development and
Matrix
Metalloproteinase Expression		 Aquat. Toxicol.100(3): 255-262 2010 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 164 days 13.4 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical EC50 14 days 158 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brian,J.V., C.A. Harris, M. Scholze, T. Backhaus,
P. Booy, M. Lamoree, G. Pojana, N. Jonkers, T.
Runnalls, A. Bonfa, A.		 Accurate Prediction of the Response of Freshwater
Fish to a Mixture of Estrogenic Chemicals		 Environ. Health Perspect.113(6): 721-728 2005 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 15 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 8 hours >8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Yamaguchi,A., H. Ishibashi, S. Kohra, K. Arizono,
and N. Tominaga		 Short-Term Effects of Endocrine-Disrupting
Chemicals on the Expression of Estrogen-
Responsive Genes in Male Medaka (Oryzias
latipes)		 Aquat. Toxicol.72(3): 239-249 2005 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 1.75 days 5 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 444 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 7 days 10000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., T. Van Es, K.R. Cooper, L.A.
White, and M.M. Haggblom		 Microbially Mediated O-Methylation of Bisphenol A
Results in Metabolites with Increased Toxicity
to the Developing Zebrafish (Danio rerio)
Embryo		 Environ. Sci. Technol.45(15): 6567-6574 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction 30 days 0.25～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Biochemical LOEC 21 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Van den Belt,K., R. Verheyen, and H. Witters Comparison of Vitellogenin Responses in Zebrafish
and Rainbow Trout Following Exposure to
Environmental Estrogens		 Ecotoxicol. Environ. Saf.56(2): 271-281 2003 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Accumulation LOEC 3 hours 3000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Birceanu,O., M.R. Servos, and M.M. Vijayan Bisphenol A Accumulation in Eggs Disrupts the
Endocrine Regulation of Growth in Rainbow Trout
Larvae		 Aquat. Toxicol.161:51-60 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects 4 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,O., A. Takesono, M. Tada, C.R. Tyler, and T.
Kudoh		 Biosensor Zebrafish Provide New Insights into
Potential Health Effects of Environmental
Estrogens		 Environ. Health Perspect.120(7): 990-996 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects 90 days 0.2～20 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 21 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Warner,K.E., and J.J. Jenkins Effects of 17alpha-Ethinylestradiol and Bisphenol
A on Vertebral Development in the Fathead Minnow
(Pimephales promelas)		 Environ. Toxicol. Chem.26(4): 732-737 2007 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Biochemical 60 days 0.1～1000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Minghong,W., X. Hai, Y. Ming, and X. Gang Effects of Chronic Bisphenol A Exposure on
Hepatic Antioxidant Parameters in Medaka
(Oryzias latipes)		 Toxicol. Environ. Chem.93(2): 270-278 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 2 days 4600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Alexander,H.C., D.C. Dill, L.W. Smith, P.D.
Guiney, and P. Dorn		 Bisphenol A: Acute Aquatic Toxicity Environ. Toxicol. Chem.7(1): 19-26 1988 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction LOEC 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Growth EC50 2.83 days 0.02 mM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Selderslaghs,I.W.T., R. Blust, and H.E. Witters Feasibility Study of the Zebrafish Assay as an
Alternative Method to Screen for Developmental
Toxicity and Embryotoxicity Using a Training
Set of 27 Compounds		 Reprod. Toxicol.33(2): 142-154 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 1 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth NOEC 4 days 10 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Growth EC50 4 days 11300 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., X. Zhang, M. Hecker, C. Schafers, R.
Fischer, and M. Fenske		 Species-Specific Considerations in Using the Fish
Embryo Test as an Alternative to Identify
Endocrine Disruption		 Aquat. Toxicol.155:62-72 2014 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality NOEC 4 days 0.1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior LOEC 4.75 days 1 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth 21 days 593～3804 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kang,I.J., H. Yokota, Y. Oshima, Y. Tsuruda, T.
Oe, N. Imada, H. Tadokoro, and T. Honjo		 Effects of Bisphenol A on the Reproduction of
Japanese Medaka (Oryzias latipes)		 Environ. Toxicol. Chem.21(11): 2394-2400 2002 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 4 days 0.97 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 164 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Reproduction 21 days 593～3804 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kang,I.J., H. Yokota, Y. Oshima, Y. Tsuruda, T.
Oe, N. Imada, H. Tadokoro, and T. Honjo		 Effects of Bisphenol A on the Reproduction of
Japanese Medaka (Oryzias latipes)		 Environ. Toxicol. Chem.21(11): 2394-2400 2002 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 295 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Growth LOEC 226 days 10 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Accumulation 0.1 mM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Fei,X.C., C. Song, and H.W. Gao Transmembrane Transports of Acrylamide and
Bisphenol A and Effects on Development of
Zebrafish (Danio rerio)		 J. Hazard. Mater.184(1-3): 81-88 2010 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality 0.03 mM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Fei,X.C., C. Song, and H.W. Gao Transmembrane Transports of Acrylamide and
Bisphenol A and Effects on Development of
Zebrafish (Danio rerio)		 J. Hazard. Mater.184(1-3): 81-88 2010 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 1 days 1000 pM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Moffatt,L.T., K.D. Fagan-Solis, E.P. Browne, and
K.F. Arcaro		 Vitellogenin and 11beta Hydroxylase mRNA
Expression in Male Japanese Medaka (Oryzias
latipes) Exposed in a Short Term
Laboratory Assay to Low Levels
of Three Estrogenic
Contaminants		 Environ. Indicators J.:16 p. 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 3 days 1000 pM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Moffatt,L.T., K.D. Fagan-Solis, E.P. Browne, and
K.F. Arcaro		 Vitellogenin and 11beta Hydroxylase mRNA
Expression in Male Japanese Medaka (Oryzias
latipes) Exposed in a Short Term
Laboratory Assay to Low Levels
of Three Estrogenic
Contaminants		 Environ. Indicators J.:16 p. 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Physiology NOEC 2.96 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Cypher,A.D., J.R. Ickes, and B. Bagatto Bisphenol A Alters the Cardiovascular Response to
Hypoxia in Danio rerio Embryos		 Comp. Biochem. Physiol. C Toxicol. Pharmacol.
174/175:39-45		 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 1.67 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 8 hours 8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Yamaguchi,A., H. Ishibashi, S. Kohra, K. Arizono,
and N. Tominaga		 Short-Term Effects of Endocrine-Disrupting
Chemicals on the Expression of Estrogen-
Responsive Genes in Male Medaka (Oryzias
latipes)		 Aquat. Toxicol.72(3): 239-249 2005 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 30 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Biochemical NOEC 106～556 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lindholst,C., K.L. Pedersen, and S.N. Pedersen Estrogenic Response of Bisphenol A in Rainbow
Trout (Oncorhynchus mykiss)		 Aquat. Toxicol.48(2-3): 87-94 2000 2016/03/25
魚類 Danio rerio (Zebrafish) Growth 4 days 0.0075～0.12 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Fei,X.C., C. Song, and H.W. Gao Transmembrane Transports of Acrylamide and
Bisphenol A and Effects on Development of
Zebrafish (Danio rerio)		 J. Hazard. Mater.184(1-3): 81-88 2010 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 44 days 60 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 5 days 3420 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R.
Cooper, and L.A. White		 Embryonic Exposure to Tetrabromobisphenol A and
Its Metabolites, Bisphenol A and
Tetrabromobisphenol A Dimethyl Ether Disrupts
Normal Zebrafish (Danio
rerio) Development and
Matrix
Metalloproteinase Expression		 Aquat. Toxicol.100(3): 255-262 2010 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth 21 days 593～3804 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kang,I.J., H. Yokota, Y. Oshima, Y. Tsuruda, T.
Oe, N. Imada, H. Tadokoro, and T. Honjo		 Effects of Bisphenol A on the Reproduction of
Japanese Medaka (Oryzias latipes)		 Environ. Toxicol. Chem.21(11): 2394-2400 2002 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects 44 days 6～600 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 7 days 8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., X. Zhang, M. Hecker, C. Schafers, R.
Fischer, and M. Fenske		 Species-Specific Considerations in Using the Fish
Embryo Test as an Alternative to Identify
Endocrine Disruption		 Aquat. Toxicol.155:62-72 2014 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 7 days 8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., X. Zhang, M. Hecker, C. Schafers, R.
Fischer, and M. Fenske		 Species-Specific Considerations in Using the Fish
Embryo Test as an Alternative to Identify
Endocrine Disruption		 Aquat. Toxicol.155:62-72 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 7 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., T. Van Es, K.R. Cooper, L.A.
White, and M.M. Haggblom		 Microbially Mediated O-Methylation of Bisphenol A
Results in Metabolites with Increased Toxicity
to the Developing Zebrafish (Danio rerio)
Embryo		 Environ. Sci. Technol.45(15): 6567-6574 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 6.83 days 0.1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Gasterosteus aculeatus (Three-spined stickleback) Population NOEC 165 days 53.62～93.6 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 De Kermoysan,G., S. Joachim, P. Baudoin, M.
Lonjaret, C. Tebby, F. Lesaulnier, F. Lestremau,
C. Chatellier, Z. Akrour, E		 Effects of Bisphenol A on Different Trophic
Levels in a Lotic Experimental Ecosystem		 Aquat. Toxicol.144-145:186-198 2013 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 4 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 30 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth NOEC 44 days 600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth 164 days >0.1～<1280 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth 164 days >0.1～<1280 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality 21 days 593～3804 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kang,I.J., H. Yokota, Y. Oshima, Y. Tsuruda, T.
Oe, N. Imada, H. Tadokoro, and T. Honjo		 Effects of Bisphenol A on the Reproduction of
Japanese Medaka (Oryzias latipes)		 Environ. Toxicol. Chem.21(11): 2394-2400 2002 2016/03/25
魚類 Danio rerio (Zebrafish) Growth LOEC 75 days >=1500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Segner,H., K. Caroll, M. Fenske, C.R. Janssen, G.
Maack, D. Pascoe, C. Schafers, G.F. Vandenbergh,
M. Watts, and A. Wenz		 Identification of Endocrine-Disrupting Effects in
Aquatic Vertebrates and Invertebrates: Report
from the European IDEA Project		 Ecotoxicol. Environ. Saf.54(3): 302-314 2003 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 3 days 4600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Alexander,H.C., D.C. Dill, L.W. Smith, P.D.
Guiney, and P. Dorn		 Bisphenol A: Acute Aquatic Toxicity Environ. Toxicol. Chem.7(1): 19-26 1988 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 4 days 0.97 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 164 days 52.8 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 15 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Physiology NOEC 2.96 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Cypher,A.D., J.R. Ickes, and B. Bagatto Bisphenol A Alters the Cardiovascular Response to
Hypoxia in Danio rerio Embryos		 Comp. Biochem. Physiol. C Toxicol. Pharmacol.
174/175:39-45		 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality 4 days 3930 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chan,W.K., and K.M. Chan Disruption of the Hypothalamic-Pituitary-Thyroid
Axis in Zebrafish Embryo-Larvae Following
Waterborne Exposure to BDE-47, TBBPA and BPA		 Aquat. Toxicol.108:106-111 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 185 days >640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 444 days >640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Biochemical NOEC 7 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sakuyama,H., Y. Endo, K. Fujimoto, and Y. Hatano Oxidative Degradation of Alkylphenols by
Horseradish Peroxidase		 J. Biosci. Bioeng.96(3): 227-231 2003 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 3.75 days 1 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 44 days 60 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction NOEC 30 days 0.25～0.61 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth NOEC 44 days 600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LOEC 5 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., T. Van Es, K.R. Cooper, L.A.
White, and M.M. Haggblom		 Microbially Mediated O-Methylation of Bisphenol A
Results in Metabolites with Increased Toxicity
to the Developing Zebrafish (Danio rerio)
Embryo		 Environ. Sci. Technol.45(15): 6567-6574 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 21 days 200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Van den Belt,K., R. Verheyen, and H. Witters Comparison of Vitellogenin Responses in Zebrafish
and Rainbow Trout Following Exposure to
Environmental Estrogens		 Ecotoxicol. Environ. Saf.56(2): 271-281 2003 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth 164 days >0.1～<1280 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Danio rerio (Zebrafish) Growth 2 days 5000～20000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Plahuta,M., T. Tisler, M.J. Toman, and A. Pintar Efficiency of Advanced Oxidation Processes in
Lowering Bisphenol A Toxicity and Oestrogenic
Activity in Aqueous Samples		 Arh. Hig. Rada Toksikol.65(1): 77-87 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 7 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., T. Van Es, K.R. Cooper, L.A.
White, and M.M. Haggblom		 Microbially Mediated O-Methylation of Bisphenol A
Results in Metabolites with Increased Toxicity
to the Developing Zebrafish (Danio rerio)
Embryo		 Environ. Sci. Technol.45(15): 6567-6574 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 30 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 5 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., T. Van Es, K.R. Cooper, L.A.
White, and M.M. Haggblom		 Microbially Mediated O-Methylation of Bisphenol A
Results in Metabolites with Increased Toxicity
to the Developing Zebrafish (Danio rerio)
Embryo		 Environ. Sci. Technol.45(15): 6567-6574 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 4 days 3930 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chan,W.K., and K.M. Chan Disruption of the Hypothalamic-Pituitary-Thyroid
Axis in Zebrafish Embryo-Larvae Following
Waterborne Exposure to BDE-47, TBBPA and BPA		 Aquat. Toxicol.108:106-111 2012 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Biochemical 0.43 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lindholst,C., S.N. Pedersen, and P. Bjerregaard Uptake, Metabolism and Excretion of Bisphenol A
in the Rainbow Trout (Oncorhynchus mykiss)		 Aquat. Toxicol.55(1-2): 75-84 2001 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 30 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction NOEC 10 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 44 days 60 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Carassius auratus (Goldfish) Biochemical NOEC 20 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Growth LOEC 226 days 10 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 43 days 160 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 43 days 1280 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 3 days 4000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Pelayo,S., E. Oliveira, B. Thienpont, P.J. Babin,
D. Raldua, M. Andre, and B. Pina		 Triiodothyronine-Induced Changes in the Zebrafish
Transcriptome During the Eleutheroembryonic
Stage: Implications for Bisphenol A
Developmental Toxicity		 Aquat. Toxicol.110:114-122 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 3 days 4000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Pelayo,S., E. Oliveira, B. Thienpont, P.J. Babin,
D. Raldua, M. Andre, and B. Pina		 Triiodothyronine-Induced Changes in the Zebrafish
Transcriptome During the Eleutheroembryonic
Stage: Implications for Bisphenol A
Developmental Toxicity		 Aquat. Toxicol.110:114-122 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Growth EC50 2 days 7500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Plahuta,M., T. Tisler, M.J. Toman, and A. Pintar Efficiency of Advanced Oxidation Processes in
Lowering Bisphenol A Toxicity and Oestrogenic
Activity in Aqueous Samples		 Arh. Hig. Rada Toksikol.65(1): 77-87 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Growth EC20 4 days 8500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., X. Zhang, M. Hecker, C. Schafers, R.
Fischer, and M. Fenske		 Species-Specific Considerations in Using the Fish
Embryo Test as an Alternative to Identify
Endocrine Disruption		 Aquat. Toxicol.155:62-72 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 20 hours 0.07 mM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Selderslaghs,I.W.T., R. Blust, and H.E. Witters Feasibility Study of the Zebrafish Assay as an
Alternative Method to Screen for Developmental
Toxicity and Embryotoxicity Using a Training
Set of 27 Compounds		 Reprod. Toxicol.33(2): 142-154 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 21 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 7 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 21 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 90 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 15 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 1 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 2 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 4 days 7.5 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 5 days 1140 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R.
Cooper, and L.A. White		 Embryonic Exposure to Tetrabromobisphenol A and
Its Metabolites, Bisphenol A and
Tetrabromobisphenol A Dimethyl Ether Disrupts
Normal Zebrafish (Danio
rerio) Development and
Matrix
Metalloproteinase Expression		 Aquat. Toxicol.100(3): 255-262 2010 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction >100～<640 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Reproduction NOEC 10.6 days 600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 6.83 days 1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 3 days 4000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Pelayo,S., E. Oliveira, B. Thienpont, P.J. Babin,
D. Raldua, M. Andre, and B. Pina		 Triiodothyronine-Induced Changes in the Zebrafish
Transcriptome During the Eleutheroembryonic
Stage: Implications for Bisphenol A
Developmental Toxicity		 Aquat. Toxicol.110:114-122 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Biochemical LOEC 20 days 0.72～4.5 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 4 days 81 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Physiology 21 days 50～5000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Zeng,Z., T. Shan, Y. Tong, S.H. Lam, and Z. Gong Development of Estrogen-Responsive Transgenic
Medaka for Environmental Monitoring of Endocrine
Disrupters		 Environ. Sci. Technol.39(22): 9001-9008 2005 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 44 days 600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 4 days 81 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 15 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 60 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 30 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 44 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 44 days 600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth NOEC 60 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Minghong,W., X. Hai, Y. Ming, and X. Gang Effects of Chronic Bisphenol A Exposure on
Hepatic Antioxidant Parameters in Medaka
(Oryzias latipes)		 Toxicol. Environ. Chem.93(2): 270-278 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 90 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Growth 90 days 10～400 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth NOEC 44 days 600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Reproduction EC50 78 days 6140 nM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Segner,H., J.M. Navas, C. Schafers, and A. Wenzel Potencies of Estrogenic Compounds in In Vitro
Screening Assays and in Life Cycle Tests with
Zebrafish In Vivo		 Ecotoxicol. Environ. Saf.54(3): 315-322 2003 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 60 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 7 days 2500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., T. Van Es, K.R. Cooper, L.A.
White, and M.M. Haggblom		 Microbially Mediated O-Methylation of Bisphenol A
Results in Metabolites with Increased Toxicity
to the Developing Zebrafish (Danio rerio)
Embryo		 Environ. Sci. Technol.45(15): 6567-6574 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 71 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 6.83 days 0.1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical LOEC 295 days 160 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 36 days 579 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior NOEC 16 hours 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 164 days 16 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 5 days 4000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M. Microbial Transformations of Tetrabromobisphenol
A and Its Metabolites, and Their Impact on
Toxicity to the Developing Zebrafish (Danio
rerio) Embryo		 Ph.D.Thesis, Rutgers, The State University of New
Jersey, New Brunswick, NJ:191 p.		 2010 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 21 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality 21 days 40～1000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Van den Belt,K., R. Verheyen, and H. Witters Comparison of Vitellogenin Responses in Zebrafish
and Rainbow Trout Following Exposure to
Environmental Estrogens		 Ecotoxicol. Environ. Saf.56(2): 271-281 2003 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects 21 days 20～500 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 44 days 600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 30 days 400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical LOEC 14 days 102 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Ankley,G.T., K.M. Jensen, M.D. Kahl, E.J. Durhan,
E.A. Makynen, J.E. Cavallin, D. Martinovic, L.C.
Wehmas, N.D. Mueller,		 Use of Chemical Mixtures to Differentiate
Mechanisms of Endocrine Action in a Small Fish
Model		 Aquat. Toxicol.99(3): 389-396 2010 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 7 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., T. Van Es, K.R. Cooper, L.A.
White, and M.M. Haggblom		 Microbially Mediated O-Methylation of Bisphenol A
Results in Metabolites with Increased Toxicity
to the Developing Zebrafish (Danio rerio)
Embryo		 Environ. Sci. Technol.45(15): 6567-6574 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 125 days 160 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 180 days 400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior LOEC 22 hours 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior LOEC 4.75 days 1 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Warner,K.E., and J.J. Jenkins Effects of 17alpha-Ethinylestradiol and Bisphenol
A on Vertebral Development in the Fathead Minnow
(Pimephales promelas)		 Environ. Toxicol. Chem.26(4): 732-737 2007 2016/03/25
魚類 Gasterosteus aculeatus (Three-spined stickleback) Population LOEC 165 days 53.62～93.6 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 De Kermoysan,G., S. Joachim, P. Baudoin, M.
Lonjaret, C. Tebby, F. Lesaulnier, F. Lestremau,
C. Chatellier, Z. Akrour, E		 Effects of Bisphenol A on Different Trophic
Levels in a Lotic Experimental Ecosystem		 Aquat. Toxicol.144-145:186-198 2013 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 44 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 4 days 8040 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chan,W.K., and K.M. Chan Disruption of the Hypothalamic-Pituitary-Thyroid
Axis in Zebrafish Embryo-Larvae Following
Waterborne Exposure to BDE-47, TBBPA and BPA		 Aquat. Toxicol.108:106-111 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 4600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Alexander,H.C., D.C. Dill, L.W. Smith, P.D.
Guiney, and P. Dorn		 Bisphenol A: Acute Aquatic Toxicity Environ. Toxicol. Chem.7(1): 19-26 1988 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 4 days 3930 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chan,W.K., and K.M. Chan Disruption of the Hypothalamic-Pituitary-Thyroid
Axis in Zebrafish Embryo-Larvae Following
Waterborne Exposure to BDE-47, TBBPA and BPA		 Aquat. Toxicol.108:106-111 2012 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Biochemical 9 days 50 mg/kg bdwt 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Christiansen,L.B., K.L. Pedersen, B. Korsgaard,
and P. Bjerregaard		 Estrogenicity of Xenobiotics in Rainbow Trout
(Oncorhynchus mykiss) Using In Vivo Synthesis of
Vitellogenin as a Biomarker		 Mar. Environ. Res.46(1-5): 137-140 1998 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 4 days 7.5 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 3.75 days 5 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 10 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical LOEC 164 days 52.8 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 20 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 3 days 4000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Thienpont,B., A. Tingaud-Sequeira, E. Prats, C.
Barata, P.J. Babin, and D. Raldua		 Zebrafish Eleutheroembryos Provide a Suitable
Vertebrate Model for Screening Chemicals that
Impair Thyroid Hormone Synthesis		 Environ. Sci. Technol.45(17): 7525-7532 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 2 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 2 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 7 days 8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., X. Zhang, M. Hecker, C. Schafers, R.
Fischer, and M. Fenske		 Species-Specific Considerations in Using the Fish
Embryo Test as an Alternative to Identify
Endocrine Disruption		 Aquat. Toxicol.155:62-72 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 7 days 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R.
Cooper, and L.A. White		 Embryonic Exposure to Tetrabromobisphenol A and
Its Metabolites, Bisphenol A and
Tetrabromobisphenol A Dimethyl Ether Disrupts
Normal Zebrafish (Danio
rerio) Development and
Matrix
Metalloproteinase Expression		 Aquat. Toxicol.100(3): 255-262 2010 2016/03/25
魚類 Gasterosteus aculeatus (Three-spined stickleback) Growth NOEC 165 days 0.47～1.72 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 De Kermoysan,G., S. Joachim, P. Baudoin, M.
Lonjaret, C. Tebby, F. Lesaulnier, F. Lestremau,
C. Chatellier, Z. Akrour, E		 Effects of Bisphenol A on Different Trophic
Levels in a Lotic Experimental Ecosystem		 Aquat. Toxicol.144-145:186-198 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Growth LOEC 226 days 10 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 2 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 44 days 6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction 164 days >0.1～<10 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 4 days 0.038 mM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Fei,X.C., C. Song, and H.W. Gao Transmembrane Transports of Acrylamide and
Bisphenol A and Effects on Development of
Zebrafish (Danio rerio)		 J. Hazard. Mater.184(1-3): 81-88 2010 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 90 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 15 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 30 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 6.83 days 0.1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Physiology NOEC 21 days 500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 2.96 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Cypher,A.D., J.R. Ickes, and B. Bagatto Bisphenol A Alters the Cardiovascular Response to
Hypoxia in Danio rerio Embryos		 Comp. Biochem. Physiol. C Toxicol. Pharmacol.
174/175:39-45		 2015 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 15 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 444 days >640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Physiology LOEC 4 days 1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth LOEC 4 days >100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 316 days 200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Biochemical 35 mg/kg bdwt 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lindholst,C., S.N. Pedersen, and P. Bjerregaard Uptake, Metabolism and Excretion of Bisphenol A
in the Rainbow Trout (Oncorhynchus mykiss)		 Aquat. Toxicol.55(1-2): 75-84 2001 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 30 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 4 days 6030 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chan,W.K., and K.M. Chan Disruption of the Hypothalamic-Pituitary-Thyroid
Axis in Zebrafish Embryo-Larvae Following
Waterborne Exposure to BDE-47, TBBPA and BPA		 Aquat. Toxicol.108:106-111 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 4 days 6030 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chan,W.K., and K.M. Chan Disruption of the Hypothalamic-Pituitary-Thyroid
Axis in Zebrafish Embryo-Larvae Following
Waterborne Exposure to BDE-47, TBBPA and BPA		 Aquat. Toxicol.108:106-111 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 3.75 days 1 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 2.96 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Cypher,A.D., J.R. Ickes, and B. Bagatto Bisphenol A Alters the Cardiovascular Response to
Hypoxia in Danio rerio Embryos		 Comp. Biochem. Physiol. C Toxicol. Pharmacol.
174/175:39-45		 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Growth LOEC 316 days 400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 30 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Biochemical 21 days 593～3804 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kang,I.J., H. Yokota, Y. Oshima, Y. Tsuruda, T.
Oe, N. Imada, H. Tadokoro, and T. Honjo		 Effects of Bisphenol A on the Reproduction of
Japanese Medaka (Oryzias latipes)		 Environ. Toxicol. Chem.21(11): 2394-2400 2002 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction 20 days 0.25～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 2 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction NOEC 90 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 2.75 days 5 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Physiology NOEC 2 days 1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction 164 days >100～<160 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction 164 days >160～<640 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 21 days 280～300 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brian,J.V., C.A. Harris, M. Scholze, A.
Kortenkamp, P. Booy, M. Lamoree, G. Pojana, N.
Jonkers, A. Marcomini, and J.P. S		 Evidence of Estrogenic Mixture Effects on the
Reproductive Performance of Fish		 Environ. Sci. Technol.41(1): 337-344 2007 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 90 days 200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Growth LOEC 226 days 10 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Biochemical NOEC 20 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical LOEC 71 days >1280 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 295 days >640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 4 days 3930 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chan,W.K., and K.M. Chan Disruption of the Hypothalamic-Pituitary-Thyroid
Axis in Zebrafish Embryo-Larvae Following
Waterborne Exposure to BDE-47, TBBPA and BPA		 Aquat. Toxicol.108:106-111 2012 2016/03/25
魚類 Poecilia reticulata (Guppy) Mortality 21 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kinnberg,K., and G. Toft Effects of Estrogenic and Antiandrogenic
Compounds on the Testis Structure of the Adult
Guppy (Poecilia reticulata)		 Ecotoxicol. Environ. Saf.54(1): 16-24 2003 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 30 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 2 days 18200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Plahuta,M., T. Tisler, M.J. Toman, and A. Pintar Efficiency of Advanced Oxidation Processes in
Lowering Bisphenol A Toxicity and Oestrogenic
Activity in Aqueous Samples		 Arh. Hig. Rada Toksikol.65(1): 77-87 2014 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth 0.1～100 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Tabata,A., S. Kashiwada, Y. Ohnishi, H. Ishikawa,
N. Miyamoto, M. Itoh, and Y. Magara		 Estrogenic Influences of Estradiol-17beta, p-
Nonylphenol and bis-Phenol-A on Japanese Medaka
(Oryzias latipes) at Detected
Environmental Concentrations		 Water Sci. Technol.43(2): 109-116 2001 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC0 2 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lysak,A., and J. Marcinek Multiple Toxic Effect of Simultaneous Action of
Some Chemical Substances on Fish		 Rocz. Nauk Roln. Ser. H Rybactwo.94(3): 53-63 1972 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC100 2 days 7000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lysak,A., and J. Marcinek Multiple Toxic Effect of Simultaneous Action of
Some Chemical Substances on Fish		 Rocz. Nauk Roln. Ser. H Rybactwo.94(3): 53-63 1972 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects LOEC 4 days 0.013 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality NOEC 6.83 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 44 days 200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior LOEC 23 hours 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Gasterosteus aculeatus (Three-spined stickleback) Growth NOEC 165 days 1.98～10.43 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 De Kermoysan,G., S. Joachim, P. Baudoin, M.
Lonjaret, C. Tebby, F. Lesaulnier, F. Lestremau,
C. Chatellier, Z. Akrour, E		 Effects of Bisphenol A on Different Trophic
Levels in a Lotic Experimental Ecosystem		 Aquat. Toxicol.144-145:186-198 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 5 days >10～<20 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Saili,K.S., M.M. Corvi, D.N. Weber, A.U. Patel, S.
R. Das, J. Przybyla, K.A. Anderson, and R.L.
Tanguay		 Neurodevelopmental Low-Dose Bisphenol A Exposure
Leads to Early Life-Stage Hyperactivity and
Learning Deficits in Adult Zebrafish		 Toxicology291(1-3): 83-92 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality IC50 3 days 9000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kashiwada,S., H. Ishikawa, N. Miyamoto, Y.
Ohnishi, and Y. Magara		 Fish Test for Endocrine-Disruption and Estimation
of Water Quality of Japanese Rivers		 Water Res.36(8): 2161-2166 2002 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 30 days 0.25～0.61 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Biochemical LOEC 20 days 0.72～4.5 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 4 days 3930 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chan,W.K., and K.M. Chan Disruption of the Hypothalamic-Pituitary-Thyroid
Axis in Zebrafish Embryo-Larvae Following
Waterborne Exposure to BDE-47, TBBPA and BPA		 Aquat. Toxicol.108:106-111 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Growth 7 days 1000～2500 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M. Microbial Transformations of Tetrabromobisphenol
A and Its Metabolites, and Their Impact on
Toxicity to the Developing Zebrafish (Danio
rerio) Embryo		 Ph.D.Thesis, Rutgers, The State University of New
Jersey, New Brunswick, NJ:191 p.		 2010 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth LOEC 2 days 1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 21 days 120～130 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brian,J.V., C.A. Harris, M. Scholze, A.
Kortenkamp, P. Booy, M. Lamoree, G. Pojana, N.
Jonkers, A. Marcomini, and J.P. S		 Evidence of Estrogenic Mixture Effects on the
Reproductive Performance of Fish		 Environ. Sci. Technol.41(1): 337-344 2007 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 3.75 days 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 444 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects 75 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Min,J., S.K. Lee, and M.B. Gu Effects of Endocrine Disrupting Chemicals on
Distinct Expression Patterns of Estrogen
Receptor, Cytochrome P450 Aromatase and
p53 Genes in Oryzias latipes
Liver		 J. Biochem. Mol. Toxicol.17(5): 272-277 2003 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 60 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects 21 days 20～500 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 21 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior LOEC 21 days 500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 60 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects 6 days 5～500 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,C., J.G. Na, K.C. Lee, and K. Park Choriogenin mRNA Induction in Male Medaka,
Oryzias latipes as a Biomarker of Endocrine
Disruption		 Aquat. Toxicol.61(3-4): 233-241 2002 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical LOEC 4 days 7.5 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior 21 days 20～500 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC100 4 days 0.12 mM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Fei,X.C., C. Song, and H.W. Gao Transmembrane Transports of Acrylamide and
Bisphenol A and Effects on Development of
Zebrafish (Danio rerio)		 J. Hazard. Mater.184(1-3): 81-88 2010 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 8 hours 800 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Yamaguchi,A., H. Ishibashi, S. Kohra, K. Arizono,
and N. Tominaga		 Short-Term Effects of Endocrine-Disrupting
Chemicals on the Expression of Estrogen-
Responsive Genes in Male Medaka (Oryzias
latipes)		 Aquat. Toxicol.72(3): 239-249 2005 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth EC50 7 days 9800 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., X. Zhang, M. Hecker, C. Schafers, R.
Fischer, and M. Fenske		 Species-Specific Considerations in Using the Fish
Embryo Test as an Alternative to Identify
Endocrine Disruption		 Aquat. Toxicol.155:62-72 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Growth 90 days 10～400 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Biochemical 0.43 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lindholst,C., S.N. Pedersen, and P. Bjerregaard Uptake, Metabolism and Excretion of Bisphenol A
in the Rainbow Trout (Oncorhynchus mykiss)		 Aquat. Toxicol.55(1-2): 75-84 2001 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth NOEC <5.9 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Metcalfe,C.D., T.L. Metcalfe, Y. Kiparissis, B.G.
Koenig, C. Khan, R.J. Hughes, T.R. Croley, R.E.
March, and T. Potter		 Estrogenic Potency of Chemicals Detected in
Sewage Treatment Plant Effluents as Determined
by In Vivo Assays with Japanese Medaka
(Oryzias latipes)		 Environ. Toxicol. Chem.20(2): 297-308 2001 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 20 days 0.72～4.5 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 44 days 6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 44 days 200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sun,L., X. Lin, R. Jin, T. Peng, Z. Peng, and Z.
Fu		 Toxic Effects of Bisphenol A on Early Life Stages
of Japanese Medaka (Oryzias latipes)		 Bull. Environ. Contam. Toxicol.93(2): 222-227 2014 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects 6 days 5～500 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,C., J.G. Na, K.C. Lee, and K. Park Choriogenin mRNA Induction in Male Medaka,
Oryzias latipes as a Biomarker of Endocrine
Disruption		 Aquat. Toxicol.61(3-4): 233-241 2002 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 4 days 81 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 185 days >640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth NOEC 2 days 0.1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction LOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 20 days 0.72～4.5 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 6.83 days 1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 160 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 164 days >1280 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 21 days 280～300 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brian,J.V., C.A. Harris, M. Scholze, A.
Kortenkamp, P. Booy, M. Lamoree, G. Pojana, N.
Jonkers, A. Marcomini, and J.P. S		 Evidence of Estrogenic Mixture Effects on the
Reproductive Performance of Fish		 Environ. Sci. Technol.41(1): 337-344 2007 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 164 days 130 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Physiology NOEC 21 days 500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth 164 days >0.1～<1280 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 14 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Molina,A.M., A.J. Lora, A. Blanco, J.G. Monterde,
N. Ayala, and R. Moyano		 Endocrine-Active Compound Evaluation: Qualitative
and Quantitative Histomorphological Assessment
of Zebrafish Gonads After Bisphenol-A Exposure		 Ecotoxicol. Environ. Saf.88:155-162 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Physiology NOEC 21 days 500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Little,A.G., and F. Seebacher Temperature Determines Toxicity: Bisphenol A
Reduces Thermal Tolerance in Fish		 Environ. Pollut.197:84-89 2015 2016/03/25
魚類 Danio rerio (Zebrafish) Reproduction 14 days 1～1000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Molina,A.M., A.J. Lora, A. Blanco, J.G. Monterde,
N. Ayala, and R. Moyano		 Endocrine-Active Compound Evaluation: Qualitative
and Quantitative Histomorphological Assessment
of Zebrafish Gonads After Bisphenol-A Exposure		 Ecotoxicol. Environ. Saf.88:155-162 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 30 days 0.72～4.5 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Growth 166 days 10～400 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Mortality 60 days 0.1～1000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Minghong,W., X. Hai, Y. Ming, and X. Gang Effects of Chronic Bisphenol A Exposure on
Hepatic Antioxidant Parameters in Medaka
(Oryzias latipes)		 Toxicol. Environ. Chem.93(2): 270-278 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical LOEC 21 days 280～300 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brian,J.V., C.A. Harris, M. Scholze, A.
Kortenkamp, P. Booy, M. Lamoree, G. Pojana, N.
Jonkers, A. Marcomini, and J.P. S		 Evidence of Estrogenic Mixture Effects on the
Reproductive Performance of Fish		 Environ. Sci. Technol.41(1): 337-344 2007 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 7 days 8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., X. Zhang, M. Hecker, C. Schafers, R.
Fischer, and M. Fenske		 Species-Specific Considerations in Using the Fish
Embryo Test as an Alternative to Identify
Endocrine Disruption		 Aquat. Toxicol.155:62-72 2014 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction LOEC 1280 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical 180 days 10～400 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Accumulation 8 hours 0.2 mM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Fei,X.C., C. Song, and H.W. Gao Transmembrane Transports of Acrylamide and
Bisphenol A and Effects on Development of
Zebrafish (Danio rerio)		 J. Hazard. Mater.184(1-3): 81-88 2010 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical NOEC 14 days 10 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Ekman,D.R., P.C. Hartig, M. Cardon, D.M. Skelton,
Q. Teng, E.J. Durhan, K.M. Jensen, M.D. Kahl, D.
L. Villeneuve, L.E.,Jr		 Metabolite Profiling and a Transcriptional
Activation Assay Provide Direct Evidence of
Androgen Receptor Antagonism by
Bisphenol A in Fish		 Environ. Sci. Technol.46(17): 9673-9680 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Reproduction LOEC 5 days 1140 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R.
Cooper, and L.A. White		 Embryonic Exposure to Tetrabromobisphenol A and
Its Metabolites, Bisphenol A and
Tetrabromobisphenol A Dimethyl Ether Disrupts
Normal Zebrafish (Danio
rerio) Development and
Matrix
Metalloproteinase Expression		 Aquat. Toxicol.100(3): 255-262 2010 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Physiology NOEC 4 days 0.1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 164 days 160 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Gasterosteus aculeatus (Three-spined stickleback) Population LOEC 165 days 53.62～93.6 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 De Kermoysan,G., S. Joachim, P. Baudoin, M.
Lonjaret, C. Tebby, F. Lesaulnier, F. Lestremau,
C. Chatellier, Z. Akrour, E		 Effects of Bisphenol A on Different Trophic
Levels in a Lotic Experimental Ecosystem		 Aquat. Toxicol.144-145:186-198 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 1 days 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 414 days >640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects LOEC 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 6.83 days 1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEL 4 days 6030 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chow,W.S., W.K.L. Chan, and K.M. Chan Toxicity Assessment and Vitellogenin Expression
in Zebrafish (Danio rerio) Embryos and Larvae
Acutely Exposed to Bisphenol A, Endosulfan,
Heptachlor, Methoxychlor and
Tetrabromobisphenol A		 J. Appl. Toxicol.33:670-678 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 7 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Growth 166 days 10～400 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction 164 days >10～<16 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Sohoni,P., C.R. Tyler, K. Hurd, J. Caunter, M.
Hetheridge, T. Williams, C. Woods, M. Evans, R.
Toy, M. Gargas, and J.P.		 Reproductive Effects of Long-Term Exposure to
Bisphenol A in the Fathead Minnow (Pimephales
promelas)		 Environ. Sci. Technol.35(14): 2917-2925 2001 2016/03/25
魚類 Danio rerio (Zebrafish) Physiology 5000～10000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M. Microbial Transformations of Tetrabromobisphenol
A and Its Metabolites, and Their Impact on
Toxicity to the Developing Zebrafish (Danio
rerio) Embryo		 Ph.D.Thesis, Rutgers, The State University of New
Jersey, New Brunswick, NJ:191 p.		 2010 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 30 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 4 days 6030 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chan,W.K., and K.M. Chan Disruption of the Hypothalamic-Pituitary-Thyroid
Axis in Zebrafish Embryo-Larvae Following
Waterborne Exposure to BDE-47, TBBPA and BPA		 Aquat. Toxicol.108:106-111 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 3 days 4000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Pelayo,S., E. Oliveira, B. Thienpont, P.J. Babin,
D. Raldua, M. Andre, and B. Pina		 Triiodothyronine-Induced Changes in the Zebrafish
Transcriptome During the Eleutheroembryonic
Stage: Implications for Bisphenol A
Developmental Toxicity		 Aquat. Toxicol.110:114-122 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 21 days 120～130 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brian,J.V., C.A. Harris, M. Scholze, A.
Kortenkamp, P. Booy, M. Lamoree, G. Pojana, N.
Jonkers, A. Marcomini, and J.P. S		 Evidence of Estrogenic Mixture Effects on the
Reproductive Performance of Fish		 Environ. Sci. Technol.41(1): 337-344 2007 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 414 days 640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Behavior LOEC 1.75 days 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality NOEC 5 days 73 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Saili,K.S., M.M. Corvi, D.N. Weber, A.U. Patel, S.
R. Das, J. Przybyla, K.A. Anderson, and R.L.
Tanguay		 Neurodevelopmental Low-Dose Bisphenol A Exposure
Leads to Early Life-Stage Hyperactivity and
Learning Deficits in Adult Zebrafish		 Toxicology291(1-3): 83-92 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality NOEC 5 days 3420 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R.
Cooper, and L.A. White		 Embryonic Exposure to Tetrabromobisphenol A and
Its Metabolites, Bisphenol A and
Tetrabromobisphenol A Dimethyl Ether Disrupts
Normal Zebrafish (Danio
rerio) Development and
Matrix
Metalloproteinase Expression		 Aquat. Toxicol.100(3): 255-262 2010 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 21 hours 5 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Cyprinus carpio (Carp) Cellular Effects 20～2000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Moens,L.N., K. Van der Ven, P. Van Remortel, J.
Del-Favero, and W.M. De Coen		 Gene Expression Analysis of Estrogenic Compounds
in the Liver of Common Carp (Cyprinus carpio)
Using a Custom cDNA Microarray		 J. Biochem. Mol. Toxicol.21(5): 299-311 2007 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth NOEC 60 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Minghong,W., X. Hai, Y. Ming, and X. Gang Effects of Chronic Bisphenol A Exposure on
Hepatic Antioxidant Parameters in Medaka
(Oryzias latipes)		 Toxicol. Environ. Chem.93(2): 270-278 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Growth 2 days 20000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Plahuta,M., T. Tisler, M.J. Toman, and A. Pintar Efficiency of Advanced Oxidation Processes in
Lowering Bisphenol A Toxicity and Oestrogenic
Activity in Aqueous Samples		 Arh. Hig. Rada Toksikol.65(1): 77-87 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Growth EC50 2.83 days 0.03 mM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Selderslaghs,I.W.T., R. Blust, and H.E. Witters Feasibility Study of the Zebrafish Assay as an
Alternative Method to Screen for Developmental
Toxicity and Embryotoxicity Using a Training
Set of 27 Compounds		 Reprod. Toxicol.33(2): 142-154 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 90 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Gasterosteus aculeatus (Three-spined stickleback) Population NOEC 165 days 53.62～93.6 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 De Kermoysan,G., S. Joachim, P. Baudoin, M.
Lonjaret, C. Tebby, F. Lesaulnier, F. Lestremau,
C. Chatellier, Z. Akrour, E		 Effects of Bisphenol A on Different Trophic
Levels in a Lotic Experimental Ecosystem		 Aquat. Toxicol.144-145:186-198 2013 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects 21 days 50～5000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Zeng,Z., T. Shan, Y. Tong, S.H. Lam, and Z. Gong Development of Estrogen-Responsive Transgenic
Medaka for Environmental Monitoring of Endocrine
Disrupters		 Environ. Sci. Technol.39(22): 9001-9008 2005 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth LOEC 4 days 1 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lee,W., C.W. Kang, C.K. Su, K. Okubo, and Y.
Nagahama		 Screening Estrogenic Activity of Environmental
Contaminants and Water Samples Using a
Transgenic Medaka Embryo Bioassay		 Chemosphere88(8): 945-952 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 8 hours 8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Yamaguchi,A., H. Ishibashi, S. Kohra, K. Arizono,
and N. Tominaga		 Short-Term Effects of Endocrine-Disrupting
Chemicals on the Expression of Estrogen-
Responsive Genes in Male Medaka (Oryzias
latipes)		 Aquat. Toxicol.72(3): 239-249 2005 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Biochemical 21 days 1402～1936 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kang,I.J., H. Yokota, Y. Oshima, Y. Tsuruda, T.
Oe, N. Imada, H. Tadokoro, and T. Honjo		 Effects of Bisphenol A on the Reproduction of
Japanese Medaka (Oryzias latipes)		 Environ. Toxicol. Chem.21(11): 2394-2400 2002 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 1 days 0.00001 mM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Gentilcore,D., I. Porreca, F. Rizzo, E. Ganbaatar,
E. Carchia, M. Mallardo, M. De Felice, and C.
Ambrosino		 Bisphenol A Interferes with Thyroid Specific Gene
Expression		 Toxicology304:21-31 2013 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 185 days >640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects NOEC 8 hours 800 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Yamaguchi,A., H. Ishibashi, S. Kohra, K. Arizono,
and N. Tominaga		 Short-Term Effects of Endocrine-Disrupting
Chemicals on the Expression of Estrogen-
Responsive Genes in Male Medaka (Oryzias
latipes)		 Aquat. Toxicol.72(3): 239-249 2005 2016/03/25
魚類 Danio rerio (Zebrafish) Reproduction NOEC 180 days 400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Growth 10～200 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Metcalfe,C.D., T.L. Metcalfe, Y. Kiparissis, B.G.
Koenig, C. Khan, R.J. Hughes, T.R. Croley, R.E.
March, and T. Potter		 Estrogenic Potency of Chemicals Detected in
Sewage Treatment Plant Effluents as Determined
by In Vivo Assays with Japanese Medaka
(Oryzias latipes)		 Environ. Toxicol. Chem.20(2): 297-308 2001 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEL 4 days 2620 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chow,W.S., W.K.L. Chan, and K.M. Chan Toxicity Assessment and Vitellogenin Expression
in Zebrafish (Danio rerio) Embryos and Larvae
Acutely Exposed to Bisphenol A, Endosulfan,
Heptachlor, Methoxychlor and
Tetrabromobisphenol A		 J. Appl. Toxicol.33:670-678 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Growth EC50 5.83 days 0.02 mM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Selderslaghs,I.W.T., R. Blust, and H.E. Witters Feasibility Study of the Zebrafish Assay as an
Alternative Method to Screen for Developmental
Toxicity and Embryotoxicity Using a Training
Set of 27 Compounds		 Reprod. Toxicol.33(2): 142-154 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality 5 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., T. Van Es, K.R. Cooper, L.A.
White, and M.M. Haggblom		 Microbially Mediated O-Methylation of Bisphenol A
Results in Metabolites with Increased Toxicity
to the Developing Zebrafish (Danio rerio)
Embryo		 Environ. Sci. Technol.45(15): 6567-6574 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Biochemical LOEC 14 days 102 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Ankley,G.T., K.M. Jensen, M.D. Kahl, E.J. Durhan,
E.A. Makynen, J.E. Cavallin, D. Martinovic, L.C.
Wehmas, N.D. Mueller,		 Use of Chemical Mixtures to Differentiate
Mechanisms of Endocrine Action in a Small Fish
Model		 Aquat. Toxicol.99(3): 389-396 2010 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 21 days 2000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kallivretaki,E., R. Eggen, S. Neuhauss, M.
Alberti, U. Kausch, and H. Segner		 Aromatase in Zebrafish: A Potential Target for
Endocrine Disrupting Chemicals		 Mar. Environ. Res.62(suppl.): S187 - S190 2006 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 60 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Biochemical NOEC 21 days 200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Van den Belt,K., R. Verheyen, and H. Witters Comparison of Vitellogenin Responses in Zebrafish
and Rainbow Trout Following Exposure to
Environmental Estrogens		 Ecotoxicol. Environ. Saf.56(2): 271-281 2003 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 43 days >1280 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 164 days 567 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Mihaich,E., J. Rhodes, J. Wolf, N. Van Der Hoeven,
D. Dietrich, A.T. Hall, N. Caspers, L. Ortego,
C. Staples, S. Dimond,		 Adult Fathead Minnow, Pimephales promelas,
Partial Life-Cycle Reproductive and Gonadal
Histopathology Study with Bisphenol A		 Environ. Toxicol. Chem.31(11): 2525-2535 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 2 days 8500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., A. Wichmann, R. Kriehuber, C.
Schafers, R. Fischer, and M. Fenske		 Transcriptome Alterations in Zebrafish Embryos
After Exposure to Environmental Estrogens and
Anti-Androgens can Reveal Endocrine
Disruption		 Reprod. Toxicol.42:210-223 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction LOEC 10 days 0.25～0.61 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Biochemical NOEC 30 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects NOEC 15 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC100 4 days 0.12 mM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Fei,X.C., C. Song, and H.W. Gao Transmembrane Transports of Acrylamide and
Bisphenol A and Effects on Development of
Zebrafish (Danio rerio)		 J. Hazard. Mater.184(1-3): 81-88 2010 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 3.75 days 1 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Biochemical 30 days 0.25～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 14 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Molina,A.M., A.J. Lora, A. Blanco, J.G. Monterde,
N. Ayala, and R. Moyano		 Endocrine-Active Compound Evaluation: Qualitative
and Quantitative Histomorphological Assessment
of Zebrafish Gonads After Bisphenol-A Exposure		 Ecotoxicol. Environ. Saf.88:155-162 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 316 days 200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Gasterosteus aculeatus (Three-spined stickleback) Population NOEC 165 days 1.98～10.43 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 De Kermoysan,G., S. Joachim, P. Baudoin, M.
Lonjaret, C. Tebby, F. Lesaulnier, F. Lestremau,
C. Chatellier, Z. Akrour, E		 Effects of Bisphenol A on Different Trophic
Levels in a Lotic Experimental Ecosystem		 Aquat. Toxicol.144-145:186-198 2013 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 16 hours 0.00001 M 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Terrien,X., J.B. Fini, B.A. Demeneix, K.W.
Schramm, and P. Prunet		 Generation of Fluorescent Zebrafish to Study
Endocrine Disruption and Potential Crosstalk
Between Thyroid Hormone and
Corticosteroids		 Aquat. Toxicol.105(1/2): 13-20 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Cellular Effects LOEC 4 days 81 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Villeneuve,D.L., N. Garcia-Reyero, B.L. Escalon,
K.M. Jensen, J.E. Cavallin, E.A. Makynen, E.J.
Durhan, M.D. Kahl, L.M.		 Ecotoxicogenomics to Support Ecological Risk
Assessment: A Case Study with Bisphenol A in
Fish		 Environ. Sci. Technol.46(1): 51-59 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical LOEC 180 days 10 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Keiter,S., L. Baumann, H. Farber, H. Holbech, D.
Skutlarek, M. Engwall, and T. Braunbeck		 Long-Term Effects of a Binary Mixture of
Perfluorooctane Sulfonate (PFOS) and Bisphenol A
(BPA) in Zebrafish (Danio rerio)		 Aquat. Toxicol.118/119:116-129 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth LOEC 431 days >640 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 6.83 days 10 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 2.75 days 15 μM 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wang,X., Q. Dong, Y. Chen, H. Jiang, Q. Xiao, Y.
Wang, W. Li, C. Bai, C. Huang, and D. Yang		 Bisphenol A Affects Axonal Growth, Musculature
and Motor Behavior in Developing Zebrafish		 Aquat. Toxicol.142/143:104-113 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Cellular Effects 60 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Reproduction NOEC 90 days 0.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction LOEC 384 days 160 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Staples,C.A., A. Tilghman Hall, U. Friederich, N.
Caspers, and G.M. Klecka		 Early Life-Stage and Multigeneration Toxicity
Study with Bisphenol A and Fathead Minnows
(Pimephales promelas)		 Ecotoxicol. Environ. Saf.74(6): 1548-1557 2011 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Biochemical 0.1～100 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kashiwada,S., H. Ishikawa, N. Miyamoto, Y.
Ohnishi, and Y. Magara		 Fish Test for Endocrine-Disruption and Estimation
of Water Quality of Japanese Rivers		 Water Res.36(8): 2161-2166 2002 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects 1 days 0.00001～0.001 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Gentilcore,D., I. Porreca, F. Rizzo, E. Ganbaatar,
E. Carchia, M. Mallardo, M. De Felice, and C.
Ambrosino		 Bisphenol A Interferes with Thyroid Specific Gene
Expression		 Toxicology304:21-31 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 20 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Biochemical NOEC 20 days 0.25～0.61 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 30 days 2.26～11.01 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., S.M.H. Alavi, A. Abdulfatah, P.
Fontaine, M. Rodina, and O. Linhart		 Adverse Effects of Bisphenol A on Reproductive
Physiology in Male Goldfish at Environmentally
Relevant Concentrations		 Ecotoxicol. Environ. Saf.76(1): 56-62 2012 2016/03/25
魚類 Oryzias latipes (Japanese medaka) Cellular Effects LOEC 7 days 8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Schiller,V., X. Zhang, M. Hecker, C. Schafers, R.
Fischer, and M. Fenske		 Species-Specific Considerations in Using the Fish
Embryo Test as an Alternative to Identify
Endocrine Disruption		 Aquat. Toxicol.155:62-72 2014 2016/03/25
魚類 Danio rerio (Zebrafish) Reproduction 14 days 1～1000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Molina,A.M., A.J. Lora, A. Blanco, J.G. Monterde,
N. Ayala, and R. Moyano		 Endocrine-Active Compound Evaluation: Qualitative
and Quantitative Histomorphological Assessment
of Zebrafish Gonads After Bisphenol-A Exposure		 Ecotoxicol. Environ. Saf.88:155-162 2013 2016/03/25
魚類 Carassius auratus (Goldfish) Growth NOEC 15 days 20 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Hatef,A., A. Zare, S.M.H. Alavi, H.R. Habibi, and
O. Linhart		 Modulations in Androgen and Estrogen Mediating
Genes and Testicular Response in Male Goldfish
Exposed to Bisphenol A		 Environ. Toxicol. Chem.31(9): 2069-2077 2012 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEC 6.83 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Danio rerio (Zebrafish) Biochemical NOEC 6.83 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Wu,M., H. Xu, Y. Shen, W. Qiu, and M. Yang Oxidative Stress in Zebrafish Embryos Induced by
Short-Term Exposure to Bisphenol A, Nonylphenol,
and Their Mixture		 Environ. Toxicol. Chem.30(10): 2335-2341 2011 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 21 days 280～300 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brian,J.V., C.A. Harris, M. Scholze, A.
Kortenkamp, P. Booy, M. Lamoree, G. Pojana, N.
Jonkers, A. Marcomini, and J.P. S		 Evidence of Estrogenic Mixture Effects on the
Reproductive Performance of Fish		 Environ. Sci. Technol.41(1): 337-344 2007 2016/03/25
魚類 Poecilia reticulata (Guppy) Reproduction 30 days 5～5000 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Kinnberg,K., and G. Toft Effects of Estrogenic and Antiandrogenic
Compounds on the Testis Structure of the Adult
Guppy (Poecilia reticulata)		 Ecotoxicol. Environ. Saf.54(1): 16-24 2003 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 21 days 280～300 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brian,J.V., C.A. Harris, M. Scholze, A.
Kortenkamp, P. Booy, M. Lamoree, G. Pojana, N.
Jonkers, A. Marcomini, and J.P. S		 Evidence of Estrogenic Mixture Effects on the
Reproductive Performance of Fish		 Environ. Sci. Technol.41(1): 337-344 2007 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Accumulation NOEC 3 hours 300 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Birceanu,O., M.R. Servos, and M.M. Vijayan Bisphenol A Accumulation in Eggs Disrupts the
Endocrine Regulation of Growth in Rainbow Trout
Larvae		 Aquat. Toxicol.161:51-60 2015 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Reproduction NOEC 21 days 120～130 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brian,J.V., C.A. Harris, M. Scholze, A.
Kortenkamp, P. Booy, M. Lamoree, G. Pojana, N.
Jonkers, A. Marcomini, and J.P. S		 Evidence of Estrogenic Mixture Effects on the
Reproductive Performance of Fish		 Environ. Sci. Technol.41(1): 337-344 2007 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Growth NOEC 21 days 120～130 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Brian,J.V., C.A. Harris, M. Scholze, A.
Kortenkamp, P. Booy, M. Lamoree, G. Pojana, N.
Jonkers, A. Marcomini, and J.P. S		 Evidence of Estrogenic Mixture Effects on the
Reproductive Performance of Fish		 Environ. Sci. Technol.41(1): 337-344 2007 2016/03/25
魚類 Gasterosteus aculeatus (Three-spined stickleback) Growth NOEC 165 days 53.62～93.6 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 De Kermoysan,G., S. Joachim, P. Baudoin, M.
Lonjaret, C. Tebby, F. Lesaulnier, F. Lestremau,
C. Chatellier, Z. Akrour, E		 Effects of Bisphenol A on Different Trophic
Levels in a Lotic Experimental Ecosystem		 Aquat. Toxicol.144-145:186-198 2013 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Biochemical NOEC 40～70 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Lindholst,C., K.L. Pedersen, and S.N. Pedersen Estrogenic Response of Bisphenol A in Rainbow
Trout (Oncorhynchus mykiss)		 Aquat. Toxicol.48(2-3): 87-94 2000 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 5 days 3420 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 McCormick,J.M., M.S. Paiva, M.M. Haggblom, K.R.
Cooper, and L.A. White		 Embryonic Exposure to Tetrabromobisphenol A and
Its Metabolites, Bisphenol A and
Tetrabromobisphenol A Dimethyl Ether Disrupts
Normal Zebrafish (Danio
rerio) Development and
Matrix
Metalloproteinase Expression		 Aquat. Toxicol.100(3): 255-262 2010 2016/03/25
魚類 Danio rerio (Zebrafish) Cellular Effects NOEC 4 days 6030 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)		 Chan,W.K., and K.M. Chan Disruption of the Hypothalamic-Pituitary-Thyroid
Axis in Zebrafish Embryo-Larvae Following
Waterborne Exposure to BDE-47, TBBPA and BPA		 Aquat. Toxicol.108:106-111 2012 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Lethal EC50 72 hours 4.7 mg/L 9 ECETOC Aquatic Toxicity, EAT Alexander ea 88 2016/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 48 hours 15.1 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) - Biodegradation and Bioaccumulation Data of
Existing Chemicals Based on the CSCL Japan		 1992 2016/02/08
魚類 Pimephales promelas (Fathead minnow) Lethal EC50 24 hours 4.7 mg/L 9 ECETOC Aquatic Toxicity, EAT Alexander ea 88 2016/02/08
魚類 Pimephales promelas (Fathead minnow) Lethal EC50 48 hours 4.7 mg/L 9 ECETOC Aquatic Toxicity, EAT Alexander ea 88 2016/02/08
魚類 Pimephales promelas (Fathead minnow) Lethal EC50 96 hours 4.7 mg/L 9 ECETOC Aquatic Toxicity, EAT Alexander ea 88 2016/02/08