生態影響に係る有害性情報


CAS登録番号 CAS RN ® : 84-66-2
官報公示整理番号 METI No. : 3-1301
物質名 test material : ジエチル=フタラート /Diethyl phthalate
水溶解度 water solubility : 1080mg/L (推計値 estimated)
LogKow : 2.42 (実測値 measured)
備考 remarks
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書) / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし 4:情報が少なく評価不能
日本環境省 化学物質の環境リスク評価(生態リスク初期評価) A:試験は信頼できる B:試験は条件付きで信頼できる C:試験の信頼性は低い D:信頼性の判定不可 E:信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり Supplemental:条件付きで信頼性あり Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり:○
なし:×
情報源 情報源による
信頼性評価**
著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value
exposure
duration
unit
toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material
original work type original work
reliability rank
author title referenced journal publication year Information
update date
藻類 Pseudokirchneriella subcapitata cell number EC50 96 hours 85.6 mg/L × × 12 ECHA Information on Registered Substances 2 Staples CA Aquatic toxicity of eighteen phthalate esters Environmental Toxicology and Chemistry, Vol. 16,
No. 5
1997
藻類 Pseudokirchneriella subcapitata cell number EC50 8 days 30.3 mg/L 12 ECHA Information on Registered Substances 2 study report 1984 2020/03/03
藻類 Desmodesmus subspicatus growth rate EC50 72 hours 45 mg/L × 12 ECHA Information on Registered Substances 2 publication 1990 2020/03/03
藻類 Desmodesmus subspicatus biomass EC50 72 hours 23 mg/L × 12 ECHA Information on Registered Substances 2 publication 1990 2020/03/03
藻類 Desmodesmus subspicatus biomass EC50 72 hours 21 mg/L × 12 ECHA Information on Registered Substances 2 publication 1990
藻類 Pseudokirchneriella subcapitata Growth EC50 4 days 30100 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
b Versteeg, D.J. Comparison of Short- and Long-Term Toxicity Test
Results for the Green Alga, Pseudokirchneriella
subcapitata.
In: W.Wang, J.W.Gorsuch, and W.R.Lower (Eds.),
Plants for Toxicity Assessment, ASTM STP 1091,
Philadelphia, PA
1990 2020/02/19
藻類 Skeletonema costatum Chlorophyll a EC50 96 hours 66 mg/L 15 WHO/IPCS CICAD US EPA Ambient water quality criteria for phthalate
esters.
Washington, DC, US Environmental Protection
Agency (EPA 440/5-80-067)
1980 2020/01/14
藻類 Scenedesmus subspicatus Cell yield EC50 96 hours 21 mg/L 15 WHO/IPCS CICAD Kuhn R, Pattard M Results of the harmful effects of water
pollutants to green algae (Scenedesmus
subspicatus) in the cell
multiplication inhibition
test.
Water Research, 24 1990 2020/01/10
藻類 Selenastrum capricornutum Growth rate EC50 96 hours 16 mg/L 15 WHO/IPCS CICAD Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms.
Environmental Toxicology and Chemistry, 14:
1569–1574.
1995 2020/01/14
藻類 Pseudokirchneriella subcapitata Biomass EC50 4 days 16000 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
a Adams, W.J., G.R. Biddinger, K.A. Robillard, and
J.W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms.
Environ.Toxicol.Chem. 14(9) 1995 2020/02/19
藻類 Selenastrum capricornutum Cell yield EC50 96 hours 86 mg/L 15 WHO/IPCS CICAD US EPA Ambient water quality criteria for phthalate
esters.
Washington, DC, US Environmental Protection
Agency (EPA 440/5-80-067)
1980 2020/01/10
藻類 Selenastrum capricornutum Chlorophyll a EC50 96 hours 90 mg/L 15 WHO/IPCS CICAD US EPA Ambient water quality criteria for phthalate
esters.
Washington, DC, US Environmental Protection
Agency (EPA 440/5-80-067)
1980 2020/01/14
藻類 Selenastrum capricornutum EC50 8 days 30.3 mg/L 14 BUA Report Springborn Bionomics Toxicity of fourteen phthalate esters to the
freshwater green alga Selenastrum capricornutum,
report no. BP-84-1-4.
NTIS/OTS0508496 #40-8426137. US Department of
Commerce, Springfield, VA.
1984 2020/01/28
藻類 Selenastrum capricornutum Cell growth EC50 96 hours 85.6 mg/L 14 BUA Report Syracuse Research Corporation Results of continuous exposure of fathead minnow
embryo to 21 priority pollutants and tables of
acute toxicity testing.
NTIS/0TS0511060 #40-7848049. US Department of
Commerce, Springfield, VA.
1978 2020/01/28
藻類 Scenedesmus subspicatus Biomass EC50 72 hours 23 mg/L 14 BUA Report Kühn, R. und Pattard, M. Results of the harmful effects of water
pollutants to green algae (Scenedesmus
subspicatus) in the cell
multiplication inhibition
test.
Water Res. 24 1990 2020/01/28
藻類 Skeletonema costatum Cell growth EC50 96 hours 85 mg/L 14 BUA Report Syracuse Research Corporation Results of continuous exposure of fathead minnow
embryo to 21 priority pollutants and tables of
acute toxicity testing.
NTIS/0TS0511060 #40-7848049. US Department of
Commerce, Springfield, VA.
1978 2020/01/28
藻類 Scenedesmus subspicatus Growth rate EC50 48 hours 62 mg/L 14 BUA Report Kühn, R. und Pattard, M. Results of the harmful effects of water
pollutants to green algae (Scenedesmus
subspicatus) in the cell
multiplication inhibition
test.
Water Res. 24 1990 2020/01/28
藻類 Scenedesmus subspicatus Biomass EC50 96 hours 21 mg/L 14 BUA Report Kühn, R. und Pattard, M. Results of the harmful effects of water
pollutants to green algae (Scenedesmus
subspicatus) in the cell
multiplication inhibition
test.
Water Res. 24 1990 2020/01/28
藻類 Skeletonema costatum Cell yield EC50 96 hours 85 mg/L 15 WHO/IPCS CICAD US EPA Ambient water quality criteria for phthalate
esters.
Washington, DC, US Environmental Protection
Agency (EPA 440/5-80-067)
1980 2020/01/14
藻類 Scenedesmus subspicatus Biomass EC50 3 days 23000 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
b Kuhn, R., and M. Pattard Results of the Harmful Effects of Water
Pollutants to Green Algae (Scenedesmus
subspicatus) in the Cell
Multiplication Inhibition
Test.
Water Res. 24(1) 1990 2020/02/19
藻類 Scenedesmus subspicatus Growth EC50 3 days 45000 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
b Kuhn, R., and M. Pattard Results of the Harmful Effects of Water
Pollutants to Green Algae (Scenedesmus
subspicatus) in the Cell
Multiplication Inhibition
Test.
Water Res. 24(1) 1990 2020/02/19
藻類 Selenastrum capricornutum Chlorophyll-A content EC50 96 hours 90.3 mg/L 14 BUA Report Syracuse Research Corporation Results of continuous exposure of fathead minnow
embryo to 21 priority pollutants and tables of
acute toxicity testing.
NTIS/0TS0511060 #40-7848049. US Department of
Commerce, Springfield, VA.
1978 2020/01/28
藻類 Scenedesmus subspicatus Biomass EC50 48 hours 35 mg/L 14 BUA Report Kühn, R. und Pattard, M. Results of the harmful effects of water
pollutants to green algae (Scenedesmus
subspicatus) in the cell
multiplication inhibition
test.
Water Res. 24 1990 2020/01/28
藻類 Scenedesmus subspicatus Growth rate EC50 72 hours 45 mg/L 14 BUA Report Kühn, R. und Pattard, M. Results of the harmful effects of water
pollutants to green algae (Scenedesmus
subspicatus) in the cell
multiplication inhibition
test.
Water Res. 24 1990 2020/01/28
藻類 Pseudokirchneriella subcapitata cell number EC50 96 hours 85.6 mg/L × × 12 ECHA Information on Registered Substances 2 Staples CA Aquatic toxicity of eighteen phthalate esters Environmental Toxicology and Chemistry, Vol. 16,
No. 5
1997
藻類 Skeletonema costatum Population/Abundance EC50 96 hours 85 ppm Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Syracuse Research Corp. Results of Continuous Exposure of Fathead Minnow
Embryo to 21 Priority Pollutants
EPA/OTS 40-7848049 1978
藻類 Pseudokirchneriella subcapitata Population/Abundance EC50 96 hours 69500 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency In-Depth Studies on Health and Environmental
Impacts of Selected Water Pollutants
U.S.EPA Contract No.68-01-4646, Duluth, MN 1978
藻類 Pseudokirchneriella subcapitata Physiology/Photosynthesis EC50 4 days 3010 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Versteeg,D.J. Comparison of Short- and Long-Term Toxicity Test
Results for the Green Alga, Selenastrum
capricornutum
ASTM Spec. Tech. Publ. 1990
藻類 Desmodesmus subspicatus Population/Biomass EC50 72 hours 23000 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kuhn,R., and M. Pattard Results of the Harmful Effects of Water
Pollutants to Green Algae (Scenedesmus
subspicatus) in the Cell
Multiplication Inhibition
Test
Water Res.24(1) 1990
藻類 Desmodesmus subspicatus Population/Population changes, general EC50 48 hours 62000 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kuhn,R., and M. Pattard Results of the Harmful Effects of Water
Pollutants to Green Algae (Scenedesmus
subspicatus) in the Cell
Multiplication Inhibition
Test
Water Res.24(1) 1990
藻類 Desmodesmus subspicatus Population/Population changes, general EC50 72 hours 45000 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kuhn,R., and M. Pattard Results of the Harmful Effects of Water
Pollutants to Green Algae (Scenedesmus
subspicatus) in the Cell
Multiplication Inhibition
Test
Water Res.24(1) 1990
藻類 Desmodesmus subspicatus Population/Biomass EC50 96 hours 21000 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kuhn,R., and M. Pattard Results of the Harmful Effects of Water
Pollutants to Green Algae (Scenedesmus
subspicatus) in the Cell
Multiplication Inhibition
Test
Water Res.24(1) 1990
藻類 Pseudokirchneriella subcapitata Physiology/Photosynthesis EC50 35 minutes >100000 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Versteeg,D.J. Comparison of Short- and Long-Term Toxicity Test
Results for the Green Alga, Selenastrum
capricornutum
ASTM Spec. Tech. Publ. 1990
藻類 Skeletonema costatum Population/Chlorophyll A concentration EC50 72 hours 71.4 ppm Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Syracuse Research Corp. Results of Continuous Exposure of Fathead Minnow
Embryo to 21 Priority Pollutants
EPA/OTS 40-7848049 1978
藻類 Skeletonema costatum Population/Chlorophyll A concentration EC50 48 hours 39.9 ppm Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Syracuse Research Corp. Results of Continuous Exposure of Fathead Minnow
Embryo to 21 Priority Pollutants
EPA/OTS 40-7848049 1978
藻類 Skeletonema costatum Population/Chlorophyll A concentration EC50 24 hours 118 ppm Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Syracuse Research Corp. Results of Continuous Exposure of Fathead Minnow
Embryo to 21 Priority Pollutants
EPA/OTS 40-7848049 1978
藻類 Pseudokirchneriella subcapitata Population/Population growth rate EC50 72 hours >0.003 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Jonsson,S., and A. Baun Toxicity of Mono- and Diesters of o-Phthalic
Esters to a Crustacean, a Green Alga, and a
Bacterium
Environ. Toxicol. Chem.22(12) 2003
藻類 Skeletonema costatum Population/Chlorophyll A concentration EC50 96 hours 65.5 ppm Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Syracuse Research Corp. Results of Continuous Exposure of Fathead Minnow
Embryo to 21 Priority Pollutants
EPA/OTS 40-7848049 1978
藻類 Desmodesmus subspicatus Population/Biomass EC50 48 hours 35000 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kuhn,R., and M. Pattard Results of the Harmful Effects of Water
Pollutants to Green Algae (Scenedesmus
subspicatus) in the Cell
Multiplication Inhibition
Test
Water Res.24(1) 1990
藻類 Pseudokirchneriella subcapitata Population/Population growth rate EC50 72 hours 70.4 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Jonsson,S., and A. Baun Toxicity of Mono- and Diesters of o-Phthalic
Esters to a Crustacean, a Green Alga, and a
Bacterium
Environ. Toxicol. Chem.22(12) 2003
藻類 Desmodesmus subspicatus biomass EC10 96 hours 13 mg/L × 12 ECHA Information on Registered Substances 2 publication 1990 2020/03/03
藻類 Desmodesmus subspicatus biomass EC10 72 hours 9 mg/L × 12 ECHA Information on Registered Substances 2 publication 1990 2020/03/03
藻類 Pseudokirchneriella subcapitata Biomass NOEC 4 days 3650 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
a Adams, W.J., G.R. Biddinger, K.A. Robillard, and
J.W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms.
Environ.Toxicol.Chem. 14(9) 1995 2020/02/19
藻類 Scenedesmus subspicatus Biomass EC10 72 hours 9 mg/L 14 BUA Report Kühn, R. und Pattard, M. Results of the harmful effects of water
pollutants to green algae (Scenedesmus
subspicatus) in the cell
multiplication inhibition
test.
Water Res. 24 1990 2020/01/29
藻類 Scenedesmus subspicatus Growth rate EC10 72 hours 9 mg/L 14 BUA Report Kühn, R. und Pattard, M. Results of the harmful effects of water
pollutants to green algae (Scenedesmus
subspicatus) in the cell
multiplication inhibition
test.
Water Res. 24 1990 2020/01/29
藻類 Scenedesmus subspicatus Biomass EC10 96 hours 13 mg/L 14 BUA Report Kühn, R. und Pattard, M. Results of the harmful effects of water
pollutants to green algae (Scenedesmus
subspicatus) in the cell
multiplication inhibition
test.
Water Res. 24 1990 2020/01/29
藻類 Selenastrum capricornutum NOEC 96 hours 3.7 mg/L 15 WHO/IPCS CICAD Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms.
Environmental Toxicology and Chemistry, 14:
1569–1574.
1995 2020/01/14
藻類 Scenedesmus subspicatus Growth rate EC10 48 hours 18 mg/L 14 BUA Report Kühn, R. und Pattard, M. Results of the harmful effects of water
pollutants to green algae (Scenedesmus
subspicatus) in the cell
multiplication inhibition
test.
Water Res. 24 1990 2020/01/29
藻類 Scenedesmus quadricauda TTC 8 days 10 mg/L 14 BUA Report Bringmann, G. und Kühn, R. Grenzwerte der Schadwirkung wassergefährdender
Stoffe gegen Bakterien (Pseudomonas putida) und
Grünalgen (Scenedesmus quadricauda) im Zell
vermehrungshemmtest.
Z. Wasser Abwasser Forsch. 10 1977 2020/01/28
藻類 Skeletonema costatum Cell growth NOEC 96 hours <39.4 mg/L 14 BUA Report Syracuse Research Corporation Results of continuous exposure of fathead minnow
embryo to 21 priority pollutants and tables of
acute toxicity testing.
NTIS/0TS0511060 #40-7848049. US Department of
Commerce, Springfield, VA.
1978 2020/01/28
藻類 Scenedesmus subspicatus Biomass EC10 48 hours 11 mg/L 14 BUA Report Kühn, R. und Pattard, M. Results of the harmful effects of water
pollutants to green algae (Scenedesmus
subspicatus) in the cell
multiplication inhibition
test.
Water Res. 24 1990 2020/01/29
藻類 Selenastrum capricornutum growth(biomass) EC50 16 mg/L 9 ECETOC Aquatic Toxicity, EAT Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms
Environ Toxicol Chem 14 1995
藻類 Desmodesmus subspicatus growth rate EC10 72 hours 9 mg/L × 12 ECHA Information on Registered Substances 2 publication 1990 2020/03/03
藻類 Scenedesmus quadricauda Population/Population growth rate LOEC 10000 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bringmann,G., and R. Kuhn Limiting Values for the Noxious Effects of Water
Pollutant Material to Blue Algae (Microcystis
aeruginosa) and Green Algae (Scenedesmus
quadricauda) in Cell Propagation
Inhibition Tests (Grenzwerte der
Schadwirkung Wass
TR-80-0201, Literature Research Company,
Annandale, VA
1978
藻類 Pseudokirchneriella subcapitata Population/Population growth rate EC10 72 hours >0.003 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Jonsson,S., and A. Baun Toxicity of Mono- and Diesters of o-Phthalic
Esters to a Crustacean, a Green Alga, and a
Bacterium
Environ. Toxicol. Chem.22(12) 2003
藻類 Pseudokirchneriella subcapitata Population/Chlorophyll A concentration NOEC 96 hours <18000 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
U.S. Environmental Protection Agency In-Depth Studies on Health and Environmental
Impacts of Selected Water Pollutants
U.S.EPA Contract No.68-01-4646, Duluth, MN 1978
藻類 Skeletonema costatum Population/Population changes, general NOEC 96 hours <39.4 ppm Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Syracuse Research Corp. Results of Continuous Exposure of Fathead Minnow
Embryo to 21 Priority Pollutants
EPA/OTS 40-7848049 1978
藻類 Pseudokirchneriella subcapitata Population/Population growth rate EC10 72 hours 22.9 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Jonsson,S., and A. Baun Toxicity of Mono- and Diesters of o-Phthalic
Esters to a Crustacean, a Green Alga, and a
Bacterium
Environ. Toxicol. Chem.22(12) 2003
藻類 Pseudokirchneriella subcapitata Population/Abundance NOEC 96 hours 3650 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Adams,W.J., G.R. Biddinger, K.A. Robillard, and J.
W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms
Environ. Toxicol. Chem.14(9) 1995
甲殻類 Mortality LC50 48 hours 0.245 mmol/L 17 Aquatic OASIS (OECD QSAR Toolbox) Peter C. von der Ohe, Ralph Kühne, Ralf-Uwe Ebert,
Rolf Altenburger, Matthias Liess, and Gerrit
Schüürmann
Structural Alerts-A New Classification Model to
Discriminate Excess Toxicity from Narcotic
Effect Levels of Organic Compounds in the
Acute Daphnid Assay
Chem. Res. Toxicol., 18 (3) 2005
甲殻類 Daphnia magna Mortality/Mortality LT50 0.02 hours 1 M Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Sugatt,R.H., D.P. O'Grady, and S. Banerjee Toxicity of Organic Mixtures Saturated in Water
to Daphnia magna. Effect of Compositional
Changes
Chemosphere13(1) 1984
甲殻類 Daphnia magna Mortality/Mortality LT50 0.12~0.15 hours 1 M Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Sugatt,R.H., D.P. O'Grady, and S. Banerjee Toxicity of Organic Mixtures Saturated in Water
to Daphnia magna. Effect of Compositional
Changes
Chemosphere13(1) 1984
甲殻類 Daphnia magna Mortality/Mortality LT50 15~24 hours 1 M Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Sugatt,R.H., D.P. O'Grady, and S. Banerjee Toxicity of Organic Mixtures Saturated in Water
to Daphnia magna. Effect of Compositional
Changes
Chemosphere13(1) 1984
甲殻類 Daphnia magna mortality LC50 48 hours 52 mg/L × × 12 ECHA Information on Registered Substances 2 publication 1980 2020/03/03
甲殻類 Daphnia magna mortality LC50 24 hours 52 mg/L × × 12 ECHA Information on Registered Substances 2 publication 1980
甲殻類 Daphnia magna mortality NOEC 48 hours 10 mg/L × × 12 ECHA Information on Registered Substances 2 publication 1980
甲殻類 Daphnia magna mortality LC50 24 hours 52 mg/L × × 12 ECHA Information on Registered Substances 2 LeBlanc GA. Acute toxicity of priority pollutants to water
flea Daphnia Magna
Bull Environm Contam. Toxicol. 24 1980 2020/03/03
甲殻類 Daphnia magna mortality LC50 48 hours 52 mg/L × × 12 ECHA Information on Registered Substances 2 LeBlanc., Gerald A. Acute toxicity of priority pollutants to water
flea Daphnia Magna
Bull Environm Contam. Toxicol. 24 1980
甲殻類 Daphnia magna mortality LC50 86 mg/L 9 ECETOC Aquatic Toxicity, EAT Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms
Environ Toxicol Chem 14 1995
甲殻類 Daphnia magna mortality LC50 48 hours 90 mg/L 12 ECHA Information on Registered Substances 2 study report 1984 2020/03/03
甲殻類 Daphnia magna mobility NOEC 48 hours 43 mg/L 12 ECHA Information on Registered Substances 2 study report 1984
甲殻類 Mysidopsis bahia LC50 96 hours 10 mg/L 15 WHO/IPCS CICAD Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms.
Environmental Toxicology and Chemistry, 14:
1569–1574.
1995 2020/01/14
甲殻類 Daphnia magna EC50 48 hours 90 mg/L 14 BUA Report Springborn Bionomics Acute toxicity of fourteen phthalate esters to
Daphnia magna, report no. BW-84-4-1567.
NTIS/0TS0508492 #40-8426082. US Department of
Commerce, Springfield, VA.
1984 2020/01/28
甲殻類 Daphnia magna Immobilization EC50 1 days 86000 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
C Kuhn, R., M. Pattard, K. Pernak, and A. Winter Results of the Harmful Effects of Water
Pollutants to Daphnia magna in the 21 Day
Reproduction Test.
Water Res. 23(4) 1989 2020/02/19
甲殻類 Nitocra spinipes Mortality LC50 4 days 74000 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
c Bengtsson, B.E., and M. Tarkpea The Acute Aquatic Toxicity of Some Substances
Carried by Ships.
Mar.Pollut.Bull. 14(6) 1983 2020/02/19
甲殻類 Daphnia magna EC50 24 hours 130 mg/L 14 BUA Report Springborn Bionomics Acute toxicity of fourteen phthalate esters to
Daphnia magna, report no. BW-84-4-1567.
NTIS/0TS0508492 #40-8426082. US Department of
Commerce, Springfield, VA.
1984 2020/01/28
甲殻類 Daphnia magna EC50 24 hours 52 mg/L 14 BUA Report LeBlanc, G.A. Acute toxicity of priority pollutants to water
flea (Daphnia magna).
Bull. Environ. Contam. Tocicol. 24 1980 2020/01/28
甲殻類 Daphnia magna EC50 24 hours 86 mg/L 14 BUA Report Kühn, R.,.Pattard, M., Pernak, K.-D. und Winter,
A.
Schadstoffwirkungen von Umweltchemikalien im
Daphnien-Reproduktions-Test als Grundlage für
die Bewertung der Umweltgefährlichkeit in
aquatischen Systemen.
Institut für Wasser-, Boden- und Lufthygiene des
Bundesgesundheitsamtes, Berlin-Dahlem, I - VI, 1
- 15, 87 - 91, Materialienband, 10 Seiten.
1988 2020/01/28
甲殻類 Mysidopsis bahia Mortality NOEC 96 hours 5.3 mg/L 14 BUA Report EG & G. Bionomics Acute toxicity of twelve phthalate esters to
mysid shrimp (Mysidopsis bahia), report no. BP-
83-1-6.
NTIS/0TS0508488 #40-8426078. US Department of
Commerce, Springfield, VA.
1984 2020/01/29
甲殻類 Daphnia magna Mortality LC50 2 days 56470 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
b Zou, E., and M. Fingerman Effects of Estrogenic Xenobiotics on Molting of
the Water Flea, Daphnia magna.
Ecotoxicol.Environ.Saf. 38(3) 1997 2020/02/19
甲殻類 Daphnia magna Immobilization EC50 48 hours 52 mg/L 15 WHO/IPCS CICAD LeBlanc GA Acute toxicity of priority pollutants to water
flea (Daphnia magna).
Bulletin of Environmental Contamination and
Toxicology, 24
1980 2020/01/10
甲殻類 Daphnia magna EC0 24 hours 50 mg/L 14 BUA Report Bringmann, G. und Kühn, R. Befunde der Schadwirkung wassergefährdender
Stoffe gegen Daphnia magna.
Z. Wasser Abwasser Forsch. 10 1977 2020/01/28
甲殻類 Americamysis bahia Mortality LC50 4 days 10300 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
a Adams, W.J., G.R. Biddinger, K.A. Robillard, and
J.W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms.
Environ.Toxicol.Chem. 14(9) 1995 2020/02/19
甲殻類 Daphnia magna EC50 24 hours 75 mg/L 14 BUA Report Bringmann, G. und Kühn, R. Befunde der Schadwirkung wassergefährdender
Stoffe gegen Daphnia magna.
Z. Wasser Abwasser Forsch. 10 1977 2020/01/28
甲殻類 Daphnia magna Mortality LC50 2 days 52000 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
b LeBlanc, G.A. Acute Toxicity of Priority Pollutants to Water
Flea (Daphnia magna).
Bull.Environ.Contam.Toxicol. 24(5) 1980 2020/02/19
甲殻類 Daphnia magna EC0 24 hours 1.6 mg/L 14 BUA Report Bringmann, G. und Kühn, R. Ergebnisse der Schadwirkung wassergefährdender
Stoffe gegen Daphnia magna in einem
weiterentwickelten standardisierten
Testverfahren.
Z. Wasser Abwasser Forsch. 15 1982 2020/01/28
甲殻類 Mysidopsis bahia NOEC 96 hours 2.7 mg/L 15 WHO/IPCS CICAD Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms.
Environmental Toxicology and Chemistry, 14:
1569–1574.
1995 2020/01/14
甲殻類 Daphnia magna Immobilization EC50 2 days 86000 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
a Adams, W.J., G.R. Biddinger, K.A. Robillard, and
J.W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms.
Environ.Toxicol.Chem. 14(9) 1995 2020/02/19
甲殻類 Mysidopsis bahia Mortality LC50 24 hours 25.5 mg/L 14 BUA Report EG & G. Bionomics Acute toxicity of twelve phthalate esters to
mysid shrimp (Mysidopsis bahia), report no. BP-
83-1-6.
NTIS/0TS0508488 #40-8426078. US Department of
Commerce, Springfield, VA.
1984 2020/01/29
甲殻類 Daphnia magna EC0 24 hours 20 mg/L 14 BUA Report Kühn, R.,.Pattard, M., Pernak, K.-D. und Winter,
A.
Schadstoffwirkungen von Umweltchemikalien im
Daphnien-Reproduktions-Test als Grundlage für
die Bewertung der Umweltgefährlichkeit in
aquatischen Systemen.
Institut für Wasser-, Boden- und Lufthygiene des
Bundesgesundheitsamtes, Berlin-Dahlem, I - VI, 1
- 15, 87 - 91, Materialienband, 10 Seiten.
1988 2020/01/28
甲殻類 Daphnia magna EC0 24 hours 10 mg/L 14 BUA Report LeBlanc, G.A. Acute toxicity of priority pollutants to water
flea (Daphnia magna).
Bull. Environ. Contam. Tocicol. 24 1980 2020/01/28
甲殻類 Mysidopsis bahia NOEC 96 hours 3.94 mg/L 14 BUA Report US EPA In-depth studies on health and environmental
impacts of selected water pollutants.
US EPA Contract No. 68-01-4646. zitiert aus:
Perwak, J., Goyer, M., Schimke, G., Eschenroeder,
A., Fiksel, J., Scow, K. und Wallace, D.
(1981) An exposure and risk assessment
for phthalate esters di(2-ethylhexyl)
phthalate, di-n-butyl phthalate,
dimethyl phthalate, diethyl
phthalate, di-n-octyl
phthalate, butyl
benzyl
phthalate. US NTIS PB 85 211936/AS. US Department of
Commerce, Springfield, VA, 6-1, 6-2, 6-4, 8-14.
1978 2020/01/29
甲殻類 Daphnia magna EC50 24 hours 41 mg/L 14 BUA Report Bringmann, G. und Kühn, R. Ergebnisse der Schadwirkung wassergefährdender
Stoffe gegen Daphnia magna in einem
weiterentwickelten standardisierten
Testverfahren.
Z. Wasser Abwasser Forsch. 15 1982 2020/01/28
甲殻類 Nitocra spinipes Mortality LC50 96 hours 74 mg/L 14 BUA Report Bengtsson, B.-E. und Tarkpea, M. The acute aquatic toxicity of some substances
carried by ships.
Mar. Pollut. Bull. 14 1983 2020/01/31
甲殻類 Mysidopsis bahia Mortality LC50 48 hours 20.1 mg/L 14 BUA Report EG & G. Bionomics Acute toxicity of twelve phthalate esters to
mysid shrimp (Mysidopsis bahia), report no. BP-
83-1-6.
NTIS/0TS0508488 #40-8426078. US Department of
Commerce, Springfield, VA.
1984 2020/01/29
甲殻類 Mysidopsis bahia LC50 96 hours 7.59 mg/L 14 BUA Report Syracuse Research Corporation Results of continuous exposure of fathead minnow
embryo to 21 priority pollutants and tables of
acute toxicity testing.
NTIS/0TS0511060 #40-7848049. US Department of
Commerce, Springfield, VA.
1978 2020/01/29
甲殻類 Daphnia magna NOEC 48 hours 10 mg/L 15 WHO/IPCS CICAD LeBlanc GA Acute toxicity of priority pollutants to water
flea (Daphnia magna).
Bulletin of Environmental Contamination and
Toxicology, 24
1980 2020/01/10
甲殻類 Daphnia magna Immoblization EC50 暴露期間 <1min. Saturated DEP concentration 14 BUA Report Sugatt, R.H., O'Grady, D.P. und Banerjee, S. Toxicity of organic mixtures saturated in water
to daphnia magna. Effect of compositional
changes.
Chemosphere 13 1984 2020/01/28
甲殻類 Daphnia magna NOEC 48 hours 38 mg/L 15 WHO/IPCS CICAD Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms.
Environmental Toxicology and Chemistry, 14:
1569–1574.
1995 2020/01/14
甲殻類 Daphnia magna LC50 48 hours 57 mg/L 15 WHO/IPCS CICAD Zou EM, Fingerman M Effects of estrogenic xenobiotics on molting of
the water flea, Daphnia magna.
Ecotoxicology and Environmental Safety, 38(3) 1997 2020/01/10
甲殻類 Daphnia magna EC50 48 hours 52 mg/L 14 BUA Report LeBlanc, G.A. Acute toxicity of priority pollutants to water
flea (Daphnia magna).
Bull. Environ. Contam. Tocicol. 24 1980 2020/01/28
甲殻類 Mysidopsis bahia Mortality LC50 96 hours 18.3 mg/L 14 BUA Report EG & G. Bionomics Acute toxicity of twelve phthalate esters to
mysid shrimp (Mysidopsis bahia), report no. BP-
83-1-6.
NTIS/0TS0508488 #40-8426078. US Department of
Commerce, Springfield, VA.
1984 2020/01/29
甲殻類 Daphnia magna Immoblization EC50 暴露期間 <1min. Saturated DEP concentration 14 BUA Report Sugatt, R.H., O'Grady, D.P. und Banerjee, S. Toxicity of organic mixtures saturated in water
to daphnia magna. Effect of compositional
changes.
Chemosphere 13 1984 2020/01/28
甲殻類 Daphnia magna Immobilization EC50 48 hours 86 mg/L 15 WHO/IPCS CICAD Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms.
Environmental Toxicology and Chemistry, 14:
1569–1574.
1995 2020/01/14
甲殻類 Mysidopsis bahia LC50 96 hours 7.6 mg/L 15 WHO/IPCS CICAD US EPA Ambient water quality criteria for phthalate
esters.
Washington, DC, US Environmental Protection
Agency (EPA 440/5-80-067)
1980 2020/01/10
甲殻類 Daphnia magna mortality LC50 24 hours 52 mg/L × × 12 ECHA Information on Registered Substances 2 LeBlanc., Gerald A. Acute toxicity of priority pollutants to water
flea Daphnia Magna
Bull Environm Contam. Toxicol. 24 1980
甲殻類 Daphnia magna mortality LC50 48 hours 52 mg/L × × 12 ECHA Information on Registered Substances 2 LeBlanc GA. Acute toxicity of priority pollutants to water
flea Daphnia Magna
Bull Environm Contam. Toxicol. 24 1980 2020/03/03
甲殻類 Daphnia magna mortality LC50 24 hours 130 mg/L 12 ECHA Information on Registered Substances 2 study report 1984 2020/03/03
甲殻類 Daphnia magna Intoxication/Immobile EC10 24 hours 61.6 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Jonsson,S., and A. Baun Toxicity of Mono- and Diesters of o-Phthalic
Esters to a Crustacean, a Green Alga, and a
Bacterium
Environ. Toxicol. Chem.22(12) 2003
甲殻類 Americamysis bahia Mortality/Mortality LC50 48 hours 20.2 ppm Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Syracuse Research Corp. Results of Continuous Exposure of Fathead Minnow
Embryo to 21 Priority Pollutants
EPA/OTS 40-7848049 1978
甲殻類 Daphnia magna Intoxication/Immobile EC10 48 hours 54.7 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Jonsson,S., and A. Baun Toxicity of Mono- and Diesters of o-Phthalic
Esters to a Crustacean, a Green Alga, and a
Bacterium
Environ. Toxicol. Chem.22(12) 2003
甲殻類 Americamysis bahia Mortality/Mortality LC50 24 hours 37.3 ppm Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Syracuse Research Corp. Results of Continuous Exposure of Fathead Minnow
Embryo to 21 Priority Pollutants
EPA/OTS 40-7848049 1978
甲殻類 Daphnia magna Intoxication/Immobile NOEC 48 hours 37500 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Adams,W.J., G.R. Biddinger, K.A. Robillard, and J.
W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms
Environ. Toxicol. Chem.14(9) 1995
甲殻類 Daphnia magna Mortality/Mortality LC50 24 hours 52000 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
LeBlanc,G.A. Acute Toxicity of Priority Pollutants to Water
Flea (Daphnia magna)
Bull. Environ. Contam. Toxicol.24(5) 1980
甲殻類 Americamysis bahia Mortality/Mortality LC50 72 hours 10.9 ppm Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Syracuse Research Corp. Results of Continuous Exposure of Fathead Minnow
Embryo to 21 Priority Pollutants
EPA/OTS 40-7848049 1978
甲殻類 Americamysis bahia Mortality/Mortality NOEC 96 hours 2700 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Adams,W.J., G.R. Biddinger, K.A. Robillard, and J.
W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms
Environ. Toxicol. Chem.14(9) 1995
甲殻類 Americamysis bahia Mortality/Mortality NOEC 96 hours 3.94 ppm Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Syracuse Research Corp. Results of Continuous Exposure of Fathead Minnow
Embryo to 21 Priority Pollutants
EPA/OTS 40-7848049 1978
甲殻類 Daphnia magna Mortality/Mortality LC50 48 hours 56470 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Zou,E., and M. Fingerman Effects of Estrogenic Xenobiotics on Molting of
the Water Flea, Daphnia magna
Ecotoxicol. Environ. Saf.38(3) 1997
甲殻類 Daphnia magna Intoxication/Immobile LC100 24 hours 200 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bringmann,G., and R. Kuhn Results of the Damaging Effect of Water
Pollutants on Daphnia magna (Befunde der
Schadwirkung Wassergefahrdender
Stoffe Gegen Daphnia magna)
TR-79-1204, Literature Research Company,
Annandale, VA
1977
甲殻類 Daphnia magna Mortality/Mortality NOEC 48 hours 10000 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
LeBlanc,G.A. Acute Toxicity of Priority Pollutants to Water
Flea (Daphnia magna)
Bull. Environ. Contam. Toxicol.24(5) 1980
甲殻類 Daphnia magna Intoxication/Immobile EC50 24 hours 86000 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kuhn,R., M. Pattard, K.D. Pernak, and A. Winter Results of the Harmful Effects of Water
Pollutants to Daphnia magna in the 21 Day
Reproduction Test
Water Res.23(4) 1989
甲殻類 Daphnia magna Intoxication/Immobile EC50 48 hours 90 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Jonsson,S., and A. Baun Toxicity of Mono- and Diesters of o-Phthalic
Esters to a Crustacean, a Green Alga, and a
Bacterium
Environ. Toxicol. Chem.22(12) 2003
甲殻類 Daphnia magna Mortality/Mortality LC50 48 hours 52000 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
LeBlanc,G.A. Acute Toxicity of Priority Pollutants to Water
Flea (Daphnia magna)
Bull. Environ. Contam. Toxicol.24(5) 1980
甲殻類 Americamysis bahia Mortality/Mortality LC50 96 hours 7.59 ppm Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Syracuse Research Corp. Results of Continuous Exposure of Fathead Minnow
Embryo to 21 Priority Pollutants
EPA/OTS 40-7848049 1978
甲殻類 Nitocra spinipes Mortality/Mortality LC50 96 hours 74000 μg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bengtsson,B.E., and M. Tarkpea The Acute Aquatic Toxicity of Some Substances
Carried by Ships
Mar. Pollut. Bull.14(6) 1983
甲殻類 Daphnia magna Intoxication/Immobile EC50 24 hours 107 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Jonsson,S., and A. Baun Toxicity of Mono- and Diesters of o-Phthalic
Esters to a Crustacean, a Green Alga, and a
Bacterium
Environ. Toxicol. Chem.22(12) 2003
甲殻類 Acartia tonsa Mortality/Mortality LC50 48 hours 9 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Andersen,H.R., L. Wollenberger, B. Halling-
Sorensen, and K.O. Kusk
Development of Copepod Nauplii to Copepodites - a
Parameter for Chronic Toxicity Including
Endocrine Disruption
Environ. Toxicol. Chem.20(12) 2001
甲殻類 Daphnia magna Intoxication/Immobile LC50 24 hours 75 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bringmann,G., and R. Kuhn Results of the Damaging Effect of Water
Pollutants on Daphnia magna (Befunde der
Schadwirkung Wassergefahrdender
Stoffe Gegen Daphnia magna)
TR-79-1204, Literature Research Company,
Annandale, VA
1977
甲殻類 Americamysis bahia Mortality/Mortality EC50 96 hours 10300 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Adams,W.J., G.R. Biddinger, K.A. Robillard, and J.
W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms
Environ. Toxicol. Chem.14(9) 1995
甲殻類 Daphnia magna Intoxication/Immobile LC0 24 hours 50 mg/L Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Bringmann,G., and R. Kuhn Results of the Damaging Effect of Water
Pollutants on Daphnia magna (Befunde der
Schadwirkung Wassergefahrdender
Stoffe Gegen Daphnia magna)
TR-79-1204, Literature Research Company,
Annandale, VA
1977
甲殻類 Daphnia magna Intoxication/Immobile EC50 48 hours 86000 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Adams,W.J., G.R. Biddinger, K.A. Robillard, and J.
W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms
Environ. Toxicol. Chem.14(9) 1995
甲殻類 Americamysis bahia Mortality LC50 4 days 7590 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
U.S.Environmental Protection Agency In-Depth Studies on Health and Environmental
Impact of Selected Water Pollutants.
U.S.EPA Contract No.68-01-4646, Duluth, MN 1978 2020/02/19
甲殻類 Daphnia magna mortality NOEC 3.8 mg/L 9 ECETOC Aquatic Toxicity, EAT Kühn R, Pattard M, Pernak KD, Winter A Results of the harmful effects of water
pollutants to Daphnia magna in the 21 day
reproduction test
Wat Res 23 1989
甲殻類 Daphnia magna reproduction NOEC 21 days 25 mg/L 12 ECHA Information on Registered Substances 2 study report 1984 2020/03/03
甲殻類 Daphnia magna mortality NOEC 21 days 25 mg/L 12 ECHA Information on Registered Substances 2 study report 1984 2020/03/03
甲殻類 Daphnia magna mortality LOEC 7.6 mg/L 9 ECETOC Aquatic Toxicity, EAT Kühn R, Pattard M, Pernak KD, Winter A Results of the harmful effects of water
pollutants to Daphnia magna in the 21 day
reproduction test
Wat Res 23 1989
甲殻類 Daphnia magna parent mortality NOEC 21 days 13 mg/L 12 ECHA Information on Registered Substances 2 publication 1989 2020/03/03
甲殻類 Daphnia magna Offspring mortality NOEC 21 days 13 mg/L 12 ECHA Information on Registered Substances 2 publication 1989 2020/03/03
甲殻類 Daphnia magna Survival/Reproduction NOEC 21 days 13 mg/L 15 WHO/IPCS CICAD Kuhn R, Pattard M, Pernak KD, Winter A Results of the harmful effects of water
pollutants to Daphnia magna in the 21-day
reproduction test.
Water Research, 23 1989 2020/01/10
甲殻類 Daphnia magna Reproduction NOEC 21 days 3800 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
a Kuhn, R., M. Pattard, K. Pernak, and A. Winter Results of the Harmful Effects of Water
Pollutants to Daphnia magna in the 21 Day
Reproduction Test.
Water Res. 23(4) 1989 2020/02/19
甲殻類 Daphnia magna 1st to 4th instar moulting LOEC 22 mg/L 15 WHO/IPCS CICAD Zou EM, Fingerman M Effects of estrogenic xenobiotics on molting of
the water flea, Daphnia magna.
Ecotoxicology and Environmental Safety, 38(3) 1997 2020/01/10
甲殻類 Daphnia magna Reproduction NOEC 21 days 25000 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
a Rhodes, J.E., W.J. Adams, G.R. Biddinger, K.A.
Robillard, and J.W. Gorsuch
Chronic Toxicity of 14 Phthalate Esters to
Daphnia magna and Rainbow Trout (Oncorhynchus
mykiss).
Environ.Toxicol.Chem. 14(11) 1995 2020/02/19
甲殻類 Daphnia magna LC45 21 days 59 mg/L 14 BUA Report Springborn Bionomics Chronic toxicity of fourteen phthalate esters to
Daphnia magna, report no. BW-84-5-1567.
NTIS/0TS0508496 #40-8426137. US Department of
Commerce, Springfield, VA.
1984 2020/01/28
甲殻類 Daphnia magna Survival/Reproduction NOEC 21 days 25 mg/L 15 WHO/IPCS CICAD Rhodes JE, Adams WJ, Biddinger GR, Robillard KA,
Gorsuch JW
Chronic toxicity of 14 phthalate esters to
Daphnia magna and rainbow trout (Oncorhynchus
mykiss).
Environmental Toxicology and Chemistry, 14(11) 1995 2020/01/10
甲殻類 Daphnia magna Reproduction LOEC 21 days 25 mg/L 14 BUA Report Kühn, R.,.Pattard, M., Pernak, K.-D. und Winter,
A.
Schadstoffwirkungen von Umweltchemikalien im
Daphnien-Reproduktions-Test als Grundlage für
die Bewertung der Umweltgefährlichkeit in
aquatischen Systemen.
Institut für Wasser-, Boden- und Lufthygiene des
Bundesgesundheitsamtes, Berlin-Dahlem, I - VI, 1
- 15, 87 - 91, Materialienband, 10 Seiten
1988 2020/01/29
甲殻類 Daphnia magna Mortality NOEC 21 days 25000 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
a Rhodes, J.E., W.J. Adams, G.R. Biddinger, K.A.
Robillard, and J.W. Gorsuch
Chronic Toxicity of 14 Phthalate Esters to
Daphnia magna and Rainbow Trout (Oncorhynchus
mykiss).
Environ.Toxicol.Chem. 14(11) 1995 2020/02/19
甲殻類 Daphnia magna Mortality, Reproduction NOEC 21 days 12.5 mg/L 14 BUA Report Kühn, R.,.Pattard, M., Pernak, K.-D. und Winter,
A.
Schadstoffwirkungen von Umweltchemikalien im
Daphnien-Reproduktions-Test als Grundlage für
die Bewertung der Umweltgefährlichkeit in
aquatischen Systemen.
Institut für Wasser-, Boden- und Lufthygiene des
Bundesgesundheitsamtes, Berlin-Dahlem, I - VI, 1
- 15, 87 - 91, Materialienband, 10 Seiten
1988 2020/01/28
甲殻類 Daphnia magna Reproduction, Mortality NOEC 21 days 25 mg/L 14 BUA Report Springborn Bionomics Chronic toxicity of fourteen phthalate esters to
Daphnia magna, report no. BW-84-5-1567.
NTIS/0TS0508496 #40-8426137. US Department of
Commerce, Springfield, VA.
1984 2020/01/28
甲殻類 Daphnia magna LC100 2 days 120 mg/L 14 BUA Report Springborn Bionomics Chronic toxicity of fourteen phthalate esters to
Daphnia magna, report no. BW-84-5-1567.
NTIS/0TS0508496 #40-8426137. US Department of
Commerce, Springfield, VA.
1984 2020/01/28
甲殻類 Daphnia magna reproduction LOEC 7.6 mg/L 9 ECETOC Aquatic Toxicity, EAT Kühn R, Pattard M, Pernak KD, Winter A Results of the harmful effects of water
pollutants to Daphnia magna in the 21 day
reproduction test
Wat Res 23 1989
甲殻類 Daphnia magna Survival/Reproduction MATC 21 days 38 mg/L 15 WHO/IPCS CICAD Rhodes JE, Adams WJ, Biddinger GR, Robillard KA,
Gorsuch JW
Chronic toxicity of 14 phthalate esters to
Daphnia magna and rainbow trout (Oncorhynchus
mykiss).
Environmental Toxicology and Chemistry, 14(11) 1995 2020/01/10
甲殻類 Daphnia magna Survival/Reproduction LOEC 21 days 59 mg/L 15 WHO/IPCS CICAD Rhodes JE, Adams WJ, Biddinger GR, Robillard KA,
Gorsuch JW
Chronic toxicity of 14 phthalate esters to
Daphnia magna and rainbow trout (Oncorhynchus
mykiss).
Environmental Toxicology and Chemistry, 14(11) 1995 2020/01/10
甲殻類 Daphnia magna mortality LOEC 59 mg/L 9 ECETOC Aquatic Toxicity, EAT Rhodes JE, Adams WJ, Biddinger GR Chronic toxicity of 14 phthalate esters to
Daphnia magna and rainbow trout (Oncorhynchus
mykiss)
Environ Toxicol Chem 14 1995
甲殻類 Daphnia magna reproduction NOEC 3.8 mg/L 9 ECETOC Aquatic Toxicity, EAT Kühn R, Pattard M, Pernak KD, Winter A Results of the harmful effects of water
pollutants to Daphnia magna in the 21 day
reproduction test
Wat Res 23 1989
甲殻類 Daphnia magna mortality NOEC 25 mg/L 9 ECETOC Aquatic Toxicity, EAT Rhodes JE, Adams WJ, Biddinger GR Chronic toxicity of 14 phthalate esters to
Daphnia magna and rainbow trout (Oncorhynchus
mykiss)
Environ Toxicol Chem 14 1995
甲殻類 Daphnia magna Mortality/Mortality LOEC 21 days 59000 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Rhodes,J.E., W.J. Adams, G.R. Biddinger, K.A.
Robillard, and J.W. Gorsuch
Chronic Toxicity of 14 Phthalate Esters to
Daphnia magna and Rainbow Trout (Oncorhynchus
mykiss)
Environ. Toxicol. Chem.14(11) 1995
甲殻類 Daphnia magna reproduction NOEC 25 mg/L 9 ECETOC Aquatic Toxicity, EAT Rhodes JE, Adams WJ, Biddinger GR Chronic toxicity of 14 phthalate esters to
Daphnia magna and rainbow trout (Oncorhynchus
mykiss)
Environ Toxicol Chem 14 1995
甲殻類 Daphnia magna reproduction LOEC 59 mg/L 9 ECETOC Aquatic Toxicity, EAT Rhodes JE, Adams WJ, Biddinger GR Chronic toxicity of 14 phthalate esters to
Daphnia magna and rainbow trout (Oncorhynchus
mykiss)
Environ Toxicol Chem 14 1995
甲殻類 Daphnia magna reproduction NOEC 21 days 13 mg/L 12 ECHA Information on Registered Substances 2 publication 1989 2020/03/03
甲殻類 Acartia tonsa Development/Slowed, Retarded, Delayed
or Non-development
EC50 5 days 10 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Andersen,H.R., L. Wollenberger, B. Halling-
Sorensen, and K.O. Kusk
Development of Copepod Nauplii to Copepodites - a
Parameter for Chronic Toxicity Including
Endocrine Disruption
Environ. Toxicol. Chem.20(12) 2001
甲殻類 Daphnia magna Reproduction/Reproduction, general NOEC 21 days 25000 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Rhodes,J.E., W.J. Adams, G.R. Biddinger, K.A.
Robillard, and J.W. Gorsuch
Chronic Toxicity of 14 Phthalate Esters to
Daphnia magna and Rainbow Trout (Oncorhynchus
mykiss)
Environ. Toxicol. Chem.14(11) 1995
甲殻類 Daphnia magna Mortality/Mortality 21 days 38400 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Rhodes,J.E., W.J. Adams, G.R. Biddinger, K.A.
Robillard, and J.W. Gorsuch
Chronic Toxicity of 14 Phthalate Esters to
Daphnia magna and Rainbow Trout (Oncorhynchus
mykiss)
Environ. Toxicol. Chem.14(11) 1995
甲殻類 Daphnia magna Mortality/Mortality 21 days 130000 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Rhodes,J.E., W.J. Adams, G.R. Biddinger, K.A.
Robillard, and J.W. Gorsuch
Chronic Toxicity of 14 Phthalate Esters to
Daphnia magna and Rainbow Trout (Oncorhynchus
mykiss)
Environ. Toxicol. Chem.14(11) 1995
甲殻類 Daphnia magna Mortality/Mortality NOEC 21 days 25000 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Rhodes,J.E., W.J. Adams, G.R. Biddinger, K.A.
Robillard, and J.W. Gorsuch
Chronic Toxicity of 14 Phthalate Esters to
Daphnia magna and Rainbow Trout (Oncorhynchus
mykiss)
Environ. Toxicol. Chem.14(11) 1995
甲殻類 Daphnia magna Reproduction/Reproduction, general 21 days 38400 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Rhodes,J.E., W.J. Adams, G.R. Biddinger, K.A.
Robillard, and J.W. Gorsuch
Chronic Toxicity of 14 Phthalate Esters to
Daphnia magna and Rainbow Trout (Oncorhynchus
mykiss)
Environ. Toxicol. Chem.14(11) 1995
甲殻類 Daphnia magna Reproduction/Reproduction, general LOEC 21 days 59000 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Rhodes,J.E., W.J. Adams, G.R. Biddinger, K.A.
Robillard, and J.W. Gorsuch
Chronic Toxicity of 14 Phthalate Esters to
Daphnia magna and Rainbow Trout (Oncorhynchus
mykiss)
Environ. Toxicol. Chem.14(11) 1995
甲殻類 Daphnia magna Reproduction/Reproduction, general NOEC 21 days 3800 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Kuhn,R., M. Pattard, K.D. Pernak, and A. Winter Results of the Harmful Effects of Water
Pollutants to Daphnia magna in the 21 Day
Reproduction Test
Water Res.23(4) 1989
魚類 Cyprinodon variegatus (Sheepshead minnow) behaviour NOEC 96 hours 10 mg/L 12 ECHA Information on Registered Substances 2 study report 1984 2020/03/04
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 120 hours 12 mg/L 12 ECHA Information on Registered Substances 2 study report 1983
魚類 Cyprinus carpio (Carp) behaviour NOEC 28 days 5 mg/L × × 12 ECHA Information on Registered Substances 2 Basre AV, Chakrabarti T, Ghosh TK, Pal AK and
Jadhao SB
Endocrine disruption and metabolic changes
following exposure of Cyprinus carpio to diethyl
phthalate
Pesticide Biochemistry and Physiology 88 2007 2020/03/04
魚類 Lepomis macrochirus (Bluegill) behaviour NOEC 96 hours <3.3 mg/L 12 ECHA Information on Registered Substances 2 study report 1983 2020/03/04
魚類 Pimephales promelas (Fathead minnow) mortality LC50 120 hours 15 mg/L 12 ECHA Information on Registered Substances 2 study report 1984 2020/03/04
魚類 Oncorhynchus mykiss (Rainbow trout) Darkened pigmentation NOEC 96 hours 1.9 mg/L 12 ECHA Information on Registered Substances 2 study report 1983 2020/03/04
魚類 Pimephales promelas (Fathead minnow) behaviour NOEC 96 hours 3 mg/L 12 ECHA Information on Registered Substances 2 study report 1983 2020/03/04
魚類 Pimephales promelas (Fathead minnow) Mortality/Mortality NOEC 144 hours <3 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
E.G. and G. Bionomics Acute Toxicity of Thirteen Phthalate Esters to
Fathead Minnow (Pimephales promelas) Under Flow-
Through Conditions
Report BW-83-3-1974, Bionomics, Wareham, MA 1983
魚類 Pimephales promelas (Fathead minnow) mortality LC50 144 hours 15 mg/L 12 ECHA Information on Registered Substances 2 study report 1984 2020/03/04
魚類 Pimephales promelas (Fathead minnow) Mortality/Mortality LC50 120 hours 15 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
E.G. and G. Bionomics Acute Toxicity of Thirteen Phthalate Esters to
Fathead Minnow (Pimephales promelas) Under Flow-
Through Conditions
Report BW-83-3-1974, Bionomics, Wareham, MA 1983
魚類 Pimephales promelas (Fathead minnow) Mortality/Mortality LOEC 144 hours 3 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
E.G. and G. Bionomics Acute Toxicity of Thirteen Phthalate Esters to
Fathead Minnow (Pimephales promelas) Under Flow-
Through Conditions
Report BW-83-3-1974, Bionomics, Wareham, MA 1983
魚類 Danio rerio (Zebrafish) Reproduction/Hatch NOEC 92 hours 427.2 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Xu,H.J., X. Shao, Z. Zhang, Y. Zou, Y. Chen, S.
Han, S. Wang, X. Wu, L. Yang, and Z. Chen
Effects of Di-n-Dutyl Phthalate and Diethyl
Phthalate on Acetylcholinesterase Activity and
Neurotoxicity Related Gene Expression in
Embryonic Zebrafish
Bull. Environ. Contam. Toxicol.91(6) 2013
魚類 Pimephales promelas (Fathead minnow) Mortality/Mortality LC50 144 hours 15 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
E.G. and G. Bionomics Acute Toxicity of Thirteen Phthalate Esters to
Fathead Minnow (Pimephales promelas) Under Flow-
Through Conditions
Report BW-83-3-1974, Bionomics, Wareham, MA 1983
魚類 Danio rerio (Zebrafish) Reproduction/Hatch NOEC 92 hours 500 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Xu,H.J., X. Shao, Z. Zhang, Y. Zou, X. Wu, and L.
Yang
Oxidative Stress and Immune Related Gene
Expression Following Exposure to Di-n-Butyl
Phthalate and Diethyl Phthalate in
Zebrafish Embryos
Ecotoxicol. Environ. Saf.93 2013
魚類 Cyprinus carpio (Carp) Morphology/Organ weight in relationship
to body weight
LOEC 28 days 1 ppm Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Barse,A.V., T. Chakrabarti, T.K. Ghosh, A.K. Pal,
and S.B. Jadhao
Endocrine Disruption and Metabolic Changes
Following Exposure of Cyprinus carpio to Diethyl
Phthalate
Pestic. Biochem. Physiol.88(1) 2007
魚類 Cyprinus carpio (Carp) Morphology/Organ weight in relationship
to body weight
LOEC 28 days 1 ppm Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Barse,A.V., T. Chakrabarti, T.K. Ghosh, A.K. Pal,
and S.B. Jadhao
Endocrine Disruption and Metabolic Changes
Following Exposure of Cyprinus carpio to Diethyl
Phthalate
Pestic. Biochem. Physiol.88(1) 2007
魚類 Pimephales promelas (Fathead minnow) mortality LC50 72 hours 20 mg/L 12 ECHA Information on Registered Substances 2 study report 1984 2020/03/04
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 48 hours 14 mg/L 12 ECHA Information on Registered Substances 2 study report 1983 2020/03/04
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 17 mg/L 12 ECHA Information on Registered Substances 2 study report 1983 2020/03/04
魚類 Lepomis macrochirus (Bluegill) mortality LC50 24 hours 34 mg/L 12 ECHA Information on Registered Substances 2 study report 1983 2020/03/04
魚類 Leuciscus idus (Orfe) LC100 48 hours 112 mg/L 14 BUA Report Juhnke, I. und Ludemann, D. Ergebnisse der Untersuchung von 200 chemischen
Verbindungen auf akute Fischtoxizität mit dem
Goldorfentest.
Z. Wasser Abwasser Forsch. H. 1978 2020/01/29
魚類 Leiostomus xanthurus (Spot) mortality LC50 16.7 mg/L 9 ECETOC Aquatic Toxicity, EAT Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms
Environ Toxicol Chem 14 1995
魚類 Pimephales promelas (Fathead minnow) mortality LC50 24 hours 30 mg/L 12 ECHA Information on Registered Substances 2 study report 1983 2020/03/04
魚類 Pimephales promelas (Fathead minnow) mortality LC50 48 hours 22 mg/L 12 ECHA Information on Registered Substances 2 study report 1984 2020/03/04
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 96 hours 22 mg/L 14 BUA Report EG & G. Bionomics Acute toxicity of thirteen phthalate esters to
bluegill (Lepomis macrochirus) report no. BW-83-
3-1368.
NTIS/0TS0508400 #40-8326141. US Department of
Commerce, Springfield, VA.
1983 2020/01/29
魚類 Cyprinodon variegatus (Sheepshead minnow) mortality LC50 72 hours 29 mg/L 12 ECHA Information on Registered Substances 2 study report 1984
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 96 hours 12 mg/L 12 ECHA Information on Registered Substances 2 study report 1983
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 72 hours 12 mg/L 12 ECHA Information on Registered Substances 2 study report 1983 2020/03/04
魚類 Lepomis macrochirus (Bluegill) Mortality NOEC 96 hours <3.3 mg/L 14 BUA Report EG & G. Bionomics Acute toxicity of thirteen phthalate esters to
bluegill (Lepomis macrochirus) report no. BW-83-
3-1368.
NTIS/0TS0508400 #40-8326141. US Department of
Commerce, Springfield, VA.
1983 2020/01/29
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 24 hours 34 mg/L 14 BUA Report EG & G. Bionomics Acute toxicity of thirteen phthalate esters to
bluegill (Lepomis macrochirus) report no. BW-83-
3-1368.
NTIS/0TS0508400 #40-8326141. US Department of
Commerce, Springfield, VA.
1983 2020/01/29
魚類 Pimephales promelas (Fathead minnow) mortality LC50 72 hours 17 mg/L 12 ECHA Information on Registered Substances 2 study report 1983 2020/03/04
魚類 Lepomis macrochirus (Bluegill) mortality LC50 72 hours 25 mg/L 12 ECHA Information on Registered Substances 2 study report 1983 2020/03/04
魚類 Pimephales promelas (Fathead minnow) mortality NOEC 96 hours <3 mg/L 12 ECHA Information on Registered Substances 2 study report 1984 2020/03/04
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 24 hours 23 mg/L 12 ECHA Information on Registered Substances 2 study report 1983 2020/03/04
魚類 Cyprinodon variegatus (Sheepshead minnow) mortality LC50 48 hours 29 mg/L 12 ECHA Information on Registered Substances 2 study report 1984
魚類 Pimephales promelas (Fathead minnow) Mortality NOEC 96 hours <3 mg/L 14 BUA Report EG & G. Bionomics Acute toxicity of thirteen phthalate esters to
fathead minnow (Pimephales promelas) under flow-
through conditions, report no. BW-83-3-1374.
NTIS/OTS0000286-0 #FYI-AX-0184-0286. US
Department of Commerce, Springfield, VA.
1983 2020/01/29
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality NOEC 96 hours 1.9 mg/L 14 BUA Report EG & G. Bionomics Acute toxicity of fourteen phthalate esters to
rainbow trout (Salmo gairdneri) under flow-
through conditions, report no. BW-83-3-1373.
NTIS/OTS0286-0 #FYI-AX-0384-0286. US Department
of Commerce, Springfield, VA.
1983 2020/01/29
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality LC50 96 hours 30 mg/L 14 BUA Report Heitmuller, P.T., Hollister, T.A. und Parrish, P.
R.
Acute toxicity of 54 industrial chemicals to
sheepshead minnows (Cyprinodon variegatus).
Bull. Environ. Contam. Toxicol. 27 1981 2020/01/29
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 96 hours 17 mg/L 14 BUA Report EG & G. Bionomics Acute toxicity of thirteen phthalate esters to
fathead minnow (Pimephales promelas) under flow-
through conditions, report no. BW-83-3-1374.
NTIS/OTS0000286-0 #FYI-AX-0184-0286. US
Department of Commerce, Springfield, VA.
1983 2020/01/29
魚類 Lepomis macrochirus (Bluegill) NOEC 96 hours 1.7 mg/L 15 WHO/IPCS CICAD Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms.
Environmental Toxicology and Chemistry, 14:
1569–1574.
1995 2020/01/14
魚類 Lepomis macrochirus (Bluegill) LC50 96 hours 17 mg/L 15 WHO/IPCS CICAD Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms.
Environmental Toxicology and Chemistry, 14:
1569–1574.
1995 2020/01/14
魚類 Oncorhynchus mykiss (Rainbow trout) LC50 96 hours 12 mg/L 15 WHO/IPCS CICAD Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms.
Environmental Toxicology and Chemistry, 14:
1569–1574.
1995 2020/01/14
魚類 Mortality LC50 96 hours 0.49 mmol/L 17 Aquatic OASIS (OECD QSAR Toolbox) Furusjö, E., Andersson, M., Rahmberg, M., Svenson,
A.
Estimating environmentally important properties
of chemicals from the chemical structure
Estimating environmentally important properties
of chemicals from the chemical structure - IVL
Rapport B1517
2003
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality NOEC 96 hours 22 mg/L 14 BUA Report Heitmuller, P.T., Hollister, T.A. und Parrish, P.
R.
Acute toxicity of 54 industrial chemicals to
sheepshead minnows (Cyprinodon variegatus).
Bull. Environ. Contam. Toxicol. 27 1981 2020/01/29
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality LC50 4 days 30000 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
c Heitmuller, P.T., T.A. Hollister, and P.R.
Parrish
Acute Toxicity of 54 Industrial Chemicals to
Sheepshead Minnows (Cyprinodon variegatus).
Bull.Environ.Contam.Toxicol. 27(5) 1981 2020/02/19
魚類 Mortality LC50 96 hours 0.24 mmol/L 17 Aquatic OASIS (OECD QSAR Toolbox) Furusjö, E., Andersson, M., Rahmberg, M., Svenson,
A.
Estimating environmentally important properties
of chemicals from the chemical structure
Estimating environmentally important properties
of chemicals from the chemical structure - IVL
Rapport B1517
2003
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality LC50 24 hours 29 mg/L 14 BUA Report Springborn Bionomics Acute toxicity of thirteen phthalate esters to
the sheepshead minnow (Cyprinodon variegatus),
report no. BP-84-2-14.
NTIS/OTS0000684-0286-1 #FYI-AX-1084-0286. US
Department of Commerce, Springfield, VA.
1984 2020/01/29
魚類 Cyprinodon variegatus (Sheepshead minnow) NOEC 96 hours 20 mg/L 15 WHO/IPCS CICAD Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms.
Environmental Toxicology and Chemistry, 14:
1569–1574.
1995 2020/01/14
魚類 Cyprinodon variegatus (Sheepshead minnow) LC50 96 hours 29 mg/L 15 WHO/IPCS CICAD Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms.
Environmental Toxicology and Chemistry, 14:
1569–1574.
1995 2020/01/14
魚類 Pimephales promelas (Fathead minnow) LC50 96 hours 17 mg/L 15 WHO/IPCS CICAD Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms.
Environmental Toxicology and Chemistry, 14:
1569–1574.
1995 2020/01/14
魚類 Mortality LC50 96 hours 0.145 mmol/L 17 Aquatic OASIS (OECD QSAR Toolbox) Russom, C.L., Bradbury, S.P., Broderius, S.J.,
Drummond, R.A. and Hammermeister, D.E.
PREDICTING MODES OF TOXIC ACTION FROM CHEMICAL
STRUCTURE: ACUTE TOXICITY IN THE FATHEAD MINNOW
(PIMEPHALES PROMELAS)
Environmental Toxicology and Chemistry, Vol. 16,
No. 5
1997
魚類 Leuciscus idus melanotus LC50 48 hours 53~61 mg/L 15 WHO/IPCS CICAD Juhnke I, Ludemann D Research results in the acute toxicity of 200
chemical substances using golden orfe test.
Zeitschrift für Wasser und Abwasser Forschung, 11 1978 2020/01/10
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality LC50 24 hours >69 mg/L 14 BUA Report Heitmuller, P.T., Hollister, T.A. und Parrish, P.
R.
Acute toxicity of 54 industrial chemicals to
sheepshead minnows (Cyprinodon variegatus).
Bull. Environ. Contam. Toxicol. 27 1981 2020/01/29
魚類 Oncorhynchus mykiss (Rainbow trout) NOEC 96 hours 3.8 mg/L 15 WHO/IPCS CICAD Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms.
Environmental Toxicology and Chemistry, 14:
1569–1574.
1995 2020/01/14
魚類 Cyprinodon variegatus (Sheepshead minnow) LC50 96 hours 30 mg/L 15 WHO/IPCS CICAD US EPA Ambient water quality criteria for phthalate
esters.
Washington, DC, US Environmental Protection
Agency (EPA 440/5-80-067)
1980 2020/01/10
魚類 Pimephales promelas (Fathead minnow) mortality LC50 17 mg/L 9 ECETOC Aquatic Toxicity, EAT Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms
Environ Toxicol Chem 14 1995
魚類 Lepomis macrochirus (Bluegill) LC50 24 hours 122 mg/L 14 BUA Report Syracuse Research Corporation Results of continuous exposure of fathead minnow
embryo to 21 priority pollutants and tables of
acute toxicity testing.
NTIS/0TS0511060 #40-7848049. US Department of
Commerce, Springfield, VA.
1978 2020/01/29
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 48 hours 25 mg/L 14 BUA Report EG & G. Bionomics Acute toxicity of thirteen phthalate esters to
bluegill (Lepomis macrochirus) report no. BW-83-
3-1368.
NTIS/0TS0508400 #40-8326141. US Department of
Commerce, Springfield, VA.
1983 2020/01/29
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality NOEC 96 hours 10 mg/L 14 BUA Report Springborn Bionomics Acute toxicity of thirteen phthalate esters to
the sheepshead minnow (Cyprinodon variegatus),
report no. BP-84-2-14.
NTIS/OTS0000684-0286-1 #FYI-AX-1084-0286. US
Department of Commerce, Springfield, VA.
1984 2020/01/29
魚類 Pimephales promelas (Fathead minnow) Mortality NOEC 96 hours 3 mg/L 14 BUA Report EG & G. Bionomics Acute toxicity of fourteen phthalate esters to
fathead minnows, report no. BW-83-3-1369.
NT1S/0TS0286-0 #FYI-AX-0184-0286. US Department
of Commerce, Springfield, VA.
1983 2020/01/29
魚類 Pimephales promelas (Fathead minnow) mortality LC50 16.8 mg/L 9 ECETOC Aquatic Toxicity, EAT Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms
Environ Toxicol Chem 14 1995
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 48 hours 17 mg/L 14 BUA Report EG & G. Bionomics Acute toxicity of fourteen phthalate esters to
fathead minnows, report no. BW-83-3-1369.
NT1S/0TS0286-0 #FYI-AX-0184-0286. US Department
of Commerce, Springfield, VA.
1983 2020/01/29
魚類 Lepomis macrochirus (Bluegill) LC50 96 hours 110 mg/L 14 BUA Report Buccafusco, R.J., Ells, S.J. und LeBlanc, G.A. Acute toxicity of priority pollutants to bluegiil
(Lepomis macrochirus).
Bull. Environ. Contam. Toxicol. 26 1981 2020/01/29
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality LC50 48 hours 38 mg/L 14 BUA Report Heitmuller, P.T., Hollister, T.A. und Parrish, P.
R.
Acute toxicity of 54 industrial chemicals to
sheepshead minnows (Cyprinodon variegatus).
Bull. Environ. Contam. Toxicol. 27 1981 2020/01/29
魚類 Lepomis macrochirus (Bluegill) LC50 24 hours 120 mg/L 14 BUA Report Buccafusco, R.J., Ells, S.J. und LeBlanc, G.A. Acute toxicity of priority pollutants to bluegiil
(Lepomis macrochirus).
Bull. Environ. Contam. Toxicol. 26 1981 2020/01/29
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 4 days 1200 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
a Adams, W.J., G.R. Biddinger, K.A. Robillard, and
J.W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms.
Environ.Toxicol.Chem. 14(9) 1995 2020/02/19
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 48 hours 22 mg/L 14 BUA Report EG & G. Bionomics Acute toxicity of thirteen phthalate esters to
fathead minnow (Pimephales promelas) under flow-
through conditions, report no. BW-83-3-1374.
NTIS/OTS0000286-0 #FYI-AX-0184-0286. US
Department of Commerce, Springfield, VA.
1983 2020/01/29
魚類 Cyprinodon variegatus (Sheepshead minnow) NOEC 96 hours 22.2 mg/L 14 BUA Report Syracuse Research Corporation Results of continuous exposure of fathead minnow
embryo to 21 priority pollutants and tables of
acute toxicity testing.
NTIS/0TS0511060 #40-7848049. US Department of
Commerce, Springfield, VA.
1978 2020/01/29
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality LC50 96 hours 29 mg/L 14 BUA Report Springborn Bionomics Acute toxicity of thirteen phthalate esters to
the sheepshead minnow (Cyprinodon variegatus),
report no. BP-84-2-14.
NTIS/OTS0000684-0286-1 #FYI-AX-1084-0286. US
Department of Commerce, Springfield, VA.
1984 2020/01/29
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality LC50 4 days 29000 mg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
b Adams, W.J., G.R. Biddinger, K.A. Robillard, and
J.W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms.
Environ.Toxicol.Chem. 14(9): 1995 2020/02/19
魚類 Pimephales promelas (Fathead minnow) NOEC 96 hours 4 mg/L 15 WHO/IPCS CICAD Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms.
Environmental Toxicology and Chemistry, 14:
1569–1574.
1995 2020/01/14
魚類 Cyprinodon variegatus (Sheepshead minnow) LC50 96 hours 29.6 mg/L 14 BUA Report Syracuse Research Corporation Results of continuous exposure of fathead minnow
embryo to 21 priority pollutants and tables of
acute toxicity testing.
NTIS/0TS0511060 #40-7848049. US Department of
Commerce, Springfield, VA.
1978 2020/01/29
魚類 Leuciscus idus (Orfe) LC0 48 hours 11 mg/L 14 BUA Report Juhnke, I. und Ludemann, D. Ergebnisse der Untersuchung von 200 chemischen
Verbindungen auf akute Fischtoxizität mit dem
Goldorfentest.
Z. Wasser Abwasser Forsch. H. 1978 2020/01/29
魚類 Lepomis macrochirus (Bluegill) mortality LC50 96 hours 22 mg/L 12 ECHA Information on Registered Substances 2 study report 1983 2020/03/04
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality LC50 48 hours 29 mg/L 14 BUA Report Springborn Bionomics Acute toxicity of thirteen phthalate esters to
the sheepshead minnow (Cyprinodon variegatus),
report no. BP-84-2-14.
NTIS/OTS0000684-0286-1 #FYI-AX-1084-0286. US
Department of Commerce, Springfield, VA.
1984 2020/01/29
魚類 Leuciscus idus (Orfe) LC50 48 hours 61 mg/L 14 BUA Report Juhnke, I. und Ludemann, D. Ergebnisse der Untersuchung von 200 chemischen
Verbindungen auf akute Fischtoxizität mit dem
Goldorfentest.
Z. Wasser Abwasser Forsch. H. 1978 2020/01/29
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 1700 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
a Adams, W.J., G.R. Biddinger, K.A. Robillard, and
J.W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms.
Environ.Toxicol.Chem. 14(9) 1995 2020/02/19
魚類 Leuciscus idus (Orfe) LC100 48 hours 67 mg/L 14 BUA Report Juhnke, I. und Ludemann, D. Ergebnisse der Untersuchung von 200 chemischen
Verbindungen auf akute Fischtoxizität mit dem
Goldorfentest.
Z. Wasser Abwasser Forsch. H. 1978 2020/01/29
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 24 hours 30 mg/L 14 BUA Report EG & G. Bionomics Acute toxicity of fourteen phthalate esters to
fathead minnows, report no. BW-83-3-1369.
NT1S/0TS0286-0 #FYI-AX-0184-0286. US Department
of Commerce, Springfield, VA.
1983 2020/01/29
魚類 Leuciscus idus (Orfe) LC0 48 hours 22 mg/L 14 BUA Report Juhnke, I. und Ludemann, D. Ergebnisse der Untersuchung von 200 chemischen
Verbindungen auf akute Fischtoxizität mit dem
Goldorfentest.
Z. Wasser Abwasser Forsch. H. 1978 2020/01/29
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 24 hours 23 mg/L 14 BUA Report EG & G. Bionomics Acute toxicity of fourteen phthalate esters to
rainbow trout (Salmo gairdneri) under flow-
through conditions, report no. BW-83-3-1373.
NTIS/OTS0286-0 #FYI-AX-0384-0286. US Department
of Commerce, Springfield, VA.
1983 2020/01/29
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 24 hours 24 mg/L 14 BUA Report EG & G. Bionomics Acute toxicity of thirteen phthalate esters to
fathead minnow (Pimephales promelas) under flow-
through conditions, report no. BW-83-3-1374.
NTIS/OTS0000286-0 #FYI-AX-0184-0286. US
Department of Commerce, Springfield, VA.
1983 2020/01/29
魚類 Lepomis macrochirus (Bluegill) LC50 96 hours 98.2 mg/L 14 BUA Report Syracuse Research Corporation Results of continuous exposure of fathead minnow
embryo to 21 priority pollutants and tables of
acute toxicity testing.
NTIS/0TS0511060 #40-7848049. US Department of
Commerce, Springfield, VA.
1978 2020/01/29
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 96 hours 12 mg/L 14 BUA Report EG & G. Bionomics Acute toxicity of fourteen phthalate esters to
rainbow trout (Salmo gairdneri) under flow-
through conditions, report no. BW-83-3-1373.
NTIS/OTS0286-0 #FYI-AX-0384-0286. US Department
of Commerce, Springfield, VA.
1983 2020/01/29
魚類 Lepomis macrochirus (Bluegill) Mortality LC50 4 days 16700 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
b Adams, W.J., G.R. Biddinger, K.A. Robillard, and
J.W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms.
Environ.Toxicol.Chem. 14(9) 1995 2020/02/19
魚類 Leuciscus idus (Orfe) LC50 48 hours 53 mg/L 14 BUA Report Juhnke, I. und Ludemann, D. Ergebnisse der Untersuchung von 200 chemischen
Verbindungen auf akute Fischtoxizität mit dem
Goldorfentest.
Z. Wasser Abwasser Forsch. H. 1978 2020/01/29
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 48 hours 14 mg/L 14 BUA Report EG & G. Bionomics Acute toxicity of fourteen phthalate esters to
rainbow trout (Salmo gairdneri) under flow-
through conditions, report no. BW-83-3-1373.
NTIS/OTS0286-0 #FYI-AX-0384-0286. US Department
of Commerce, Springfield, VA.
1983 2020/01/29
魚類 Lepomis macrochirus (Bluegill) LC50 96 hours 98 mg/L 15 WHO/IPCS CICAD US EPA Ambient water quality criteria for phthalate
esters.
Washington, DC, US Environmental Protection
Agency (EPA 440/5-80-067)
1980 2020/01/10
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 2 days 54000 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
c Tsuji, S., Y. Tonogai, Y. Ito, and S. Kanoh The Influence of Rearing Temperatures on the
Toxicity of Various Environmental Pollutants for
Killifish (Oryzias latipes).
J.Hyg.Chem./Eisei Kagaku 32(1) 1986 2020/02/19
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 96 hours 17 mg/L 14 BUA Report EG & G. Bionomics Acute toxicity of fourteen phthalate esters to
fathead minnows, report no. BW-83-3-1369.
NT1S/0TS0286-0 #FYI-AX-0184-0286. US Department
of Commerce, Springfield, VA.
1983 2020/01/29
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 1680 μg/L 6 日本環境省 
化学物質の環境リスク評価(生態リスク初期評価)
b Adams, W.J., G.R. Biddinger, K.A. Robillard, and
J.W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms.
Environ.Toxicol.Chem. 14(9) 1995 2020/02/19
魚類 Cyprinodon variegatus (Sheepshead minnow) mortality LC50 96 hours 29 mg/L 12 ECHA Information on Registered Substances 2 study report 1984
魚類 Cyprinodon variegatus (Sheepshead minnow) mortality LC50 24 hours 29 mg/L 12 ECHA Information on Registered Substances 2 study report 1984 2020/03/04
魚類 Lepomis macrochirus (Bluegill) mortality LC50 48 hours 25 mg/L 12 ECHA Information on Registered Substances 2 study report 1983 2020/03/04
魚類 Oncorhynchus mykiss (Rainbow trout) mortality LC50 12 mg/L 9 ECETOC Aquatic Toxicity, EAT Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms
Environ Toxicol Chem 14 1995
魚類 Pimephales promelas (Fathead minnow) mortality LC50 48 hours 17 mg/L 12 ECHA Information on Registered Substances 2 study report 1983 2020/03/04
魚類 Pimephales promelas (Fathead minnow) mortality LC50 96 hours 17 mg/L 12 ECHA Information on Registered Substances 2 study report 1984 2020/03/04
魚類 Cyprinodon variegatus (Sheepshead minnow) mortality LC50 29 mg/L 9 ECETOC Aquatic Toxicity, EAT Adams WJ, Biddinger GR, Robillard KA, Gorsuch JW A summary of the acute toxicity of 14 phthalate
esters to representative aquatic organisms
Environ Toxicol Chem 14 1995
魚類 Pimephales promelas (Fathead minnow) mortality LC50 24 hours 24 mg/L 12 ECHA Information on Registered Substances 2 study report 1984 2020/03/04
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality/Mortality LC50 24 hours >69 ppm Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Heitmuller,P.T., T.A. Hollister, and P.R. Parrish Acute Toxicity of 54 Industrial Chemicals to
Sheepshead Minnows (Cyprinodon variegatus)
Bull. Environ. Contam. Toxicol.27(5) 1981
魚類 Lepomis macrochirus (Bluegill) Mortality/Mortality LC50 96 hours 16700 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Adams,W.J., G.R. Biddinger, K.A. Robillard, and J.
W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms
Environ. Toxicol. Chem.14(9) 1995
魚類 Oryzias latipes (Japanese medaka) Mortality/Mortality LC50 48 hours 54000 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Tsuji,S., Y. Tonogai, Y. Ito, and S. Kanoh The Influence of Rearing Temperatures on the
Toxicity of Various Environmental Pollutants for
Killifish (Oryzias latipes)
Jpn. J. Toxicol. Environ. Health32(1) 1986
魚類 Lepomis macrochirus (Bluegill) Mortality/Mortality NOEC 96 hours 1650 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Adams,W.J., G.R. Biddinger, K.A. Robillard, and J.
W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms
Environ. Toxicol. Chem.14(9) 1995
魚類 Oryzias latipes (Japanese medaka) Mortality/Mortality LC50 48 hours 33000 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Tsuji,S., Y. Tonogai, Y. Ito, and S. Kanoh The Influence of Rearing Temperatures on the
Toxicity of Various Environmental Pollutants for
Killifish (Oryzias latipes)
Jpn. J. Toxicol. Environ. Health32(1) 1986
魚類 Pimephales promelas (Fathead minnow) Mortality/Mortality LC50 96 hours 31800 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Geiger,D.L., C.E. Northcott, D.J. Call, and L.T.
Brooke
Acute Toxicities of Organic Chemicals to Fathead
Minnows (Pimephales promelas), Volume II
Center for Lake Superior Environmental Studies,
University of Wisconsin, Superior, WI
1985
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality/Mortality LC50 72 hours 36 ppm Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Heitmuller,P.T., T.A. Hollister, and P.R. Parrish Acute Toxicity of 54 Industrial Chemicals to
Sheepshead Minnows (Cyprinodon variegatus)
Bull. Environ. Contam. Toxicol.27(5) 1981
魚類 Oryzias latipes (Japanese medaka) Mortality/Mortality LC50 48 hours 62000 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Tsuji,S., Y. Tonogai, Y. Ito, and S. Kanoh The Influence of Rearing Temperatures on the
Toxicity of Various Environmental Pollutants for
Killifish (Oryzias latipes)
Jpn. J. Toxicol. Environ. Health32(1) 1986
魚類 Lepomis macrochirus (Bluegill) Mortality/Mortality LC50 24 hours 120 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Buccafusco,R.J., S.J. Ells, and G.A. LeBlanc Acute Toxicity of Priority Pollutants to Bluegill
(Lepomis macrochirus)
Bull. Environ. Contam. Toxicol.26(4) 1981
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality/Mortality NOEC 96 hours 22 ppm Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Heitmuller,P.T., T.A. Hollister, and P.R. Parrish Acute Toxicity of 54 Industrial Chemicals to
Sheepshead Minnows (Cyprinodon variegatus)
Bull. Environ. Contam. Toxicol.27(5) 1981
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality/Mortality LC50 96 hours 12000 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Adams,W.J., G.R. Biddinger, K.A. Robillard, and J.
W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms
Environ. Toxicol. Chem.14(9) 1995
魚類 Pimephales promelas (Fathead minnow) Mortality/Mortality LC50 24 hours 24 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
E.G. and G. Bionomics Acute Toxicity of Thirteen Phthalate Esters to
Fathead Minnow (Pimephales promelas) Under Flow-
Through Conditions
Report BW-83-3-1974, Bionomics, Wareham, MA 1983
魚類 Danio rerio (Zebrafish) Mortality/Survival NOEC 92 hours 427.2 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Xu,H.J., X. Shao, Z. Zhang, Y. Zou, Y. Chen, S.
Han, S. Wang, X. Wu, L. Yang, and Z. Chen
Effects of Di-n-Dutyl Phthalate and Diethyl
Phthalate on Acetylcholinesterase Activity and
Neurotoxicity Related Gene Expression in
Embryonic Zebrafish
Bull. Environ. Contam. Toxicol.91(6) 2013
魚類 Danio rerio (Zebrafish) Mortality/Survival NOEC 92 hours 500 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Xu,H.J., X. Shao, Z. Zhang, Y. Zou, X. Wu, and L.
Yang
Oxidative Stress and Immune Related Gene
Expression Following Exposure to Di-n-Butyl
Phthalate and Diethyl Phthalate in
Zebrafish Embryos
Ecotoxicol. Environ. Saf.93 2013
魚類 Oryzias latipes (Japanese medaka) Mortality/Mortality LC50 24 hours 62000 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Tsuji,S., Y. Tonogai, Y. Ito, and S. Kanoh The Influence of Rearing Temperatures on the
Toxicity of Various Environmental Pollutants for
Killifish (Oryzias latipes)
Jpn. J. Toxicol. Environ. Health32(1) 1986
魚類 Pimephales promelas (Fathead minnow) Mortality/Mortality NOEC 96 hours 4000 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Adams,W.J., G.R. Biddinger, K.A. Robillard, and J.
W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms
Environ. Toxicol. Chem.14(9) 1995
魚類 Pimephales promelas (Fathead minnow) Mortality/Mortality NOEC 96 hours 3400 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Adams,W.J., G.R. Biddinger, K.A. Robillard, and J.
W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms
Environ. Toxicol. Chem.14(9) 1995
魚類 Cyprinus carpio (Carp) Mortality/Mortality LC50 96 hours 48 ppm Formulation 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Barse,A.V., T. Chakrabarti, T.K. Ghosh, A.K. Pal,
and S.B. Jadhao
Endocrine Disruption and Metabolic Changes
Following Exposure of Cyprinus carpio to Diethyl
Phthalate
Pestic. Biochem. Physiol.88(1) 2007
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality/Mortality NOEC 96 hours 20000 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Adams,W.J., G.R. Biddinger, K.A. Robillard, and J.
W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms
Environ. Toxicol. Chem.14(9) 1995
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality/Mortality LC50 48 hours 38 ppm Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Heitmuller,P.T., T.A. Hollister, and P.R. Parrish Acute Toxicity of 54 Industrial Chemicals to
Sheepshead Minnows (Cyprinodon variegatus)
Bull. Environ. Contam. Toxicol.27(5) 1981
魚類 Pimephales promelas (Fathead minnow) Mortality/Mortality LC50 96 hours 16800 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Adams,W.J., G.R. Biddinger, K.A. Robillard, and J.
W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms
Environ. Toxicol. Chem.14(9) 1995
魚類 Oryzias latipes (Japanese medaka) Mortality/Mortality LC50 24 hours 54000 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Tsuji,S., Y. Tonogai, Y. Ito, and S. Kanoh The Influence of Rearing Temperatures on the
Toxicity of Various Environmental Pollutants for
Killifish (Oryzias latipes)
Jpn. J. Toxicol. Environ. Health32(1) 1986
魚類 Pimephales promelas (Fathead minnow) Mortality/Mortality LC50 96 hours 17000 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Adams,W.J., G.R. Biddinger, K.A. Robillard, and J.
W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms
Environ. Toxicol. Chem.14(9) 1995
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality/Mortality NOEC 96 hours 3800 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Adams,W.J., G.R. Biddinger, K.A. Robillard, and J.
W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms
Environ. Toxicol. Chem.14(9) 1995
魚類 Lepomis macrochirus (Bluegill) Mortality/Mortality LC50 96 hours 110 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Buccafusco,R.J., S.J. Ells, and G.A. LeBlanc Acute Toxicity of Priority Pollutants to Bluegill
(Lepomis macrochirus)
Bull. Environ. Contam. Toxicol.26(4) 1981
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality/Mortality LC50 96 hours 29000 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Adams,W.J., G.R. Biddinger, K.A. Robillard, and J.
W. Gorsuch
A Summary of the Acute Toxicity of 14 Phthalate
Esters to Representative Aquatic Organisms
Environ. Toxicol. Chem.14(9) 1995
魚類 Pimephales promelas (Fathead minnow) Mortality/Mortality LC50 72 hours 20 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
E.G. and G. Bionomics Acute Toxicity of Thirteen Phthalate Esters to
Fathead Minnow (Pimephales promelas) Under Flow-
Through Conditions
Report BW-83-3-1974, Bionomics, Wareham, MA 1983
魚類 Cyprinodon variegatus (Sheepshead minnow) Mortality/Mortality LC50 96 hours 30 ppm Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Heitmuller,P.T., T.A. Hollister, and P.R. Parrish Acute Toxicity of 54 Industrial Chemicals to
Sheepshead Minnows (Cyprinodon variegatus)
Bull. Environ. Contam. Toxicol.27(5) 1981
魚類 Pimephales promelas (Fathead minnow) Mortality/Mortality LC50 48 hours 22 mg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
E.G. and G. Bionomics Acute Toxicity of Thirteen Phthalate Esters to
Fathead Minnow (Pimephales promelas) Under Flow-
Through Conditions
Report BW-83-3-1974, Bionomics, Wareham, MA 1983
魚類 Oryzias latipes (Japanese medaka) Mortality/Mortality LC50 24 hours 33000 μg/L Active ingredient 16 US EPA AQUIRE (AQUatic toxicity Information
REtrieval)
Tsuji,S., Y. Tonogai, Y. Ito, and S. Kanoh The Influence of Rearing Temperatures on the
Toxicity of Various Environmental Pollutants for
Killifish (Oryzias latipes)
Jpn. J. Toxicol. Environ. Health32(1) 1986