生態影響に係る有害性情報


CAS登録番号 CAS RN ® : 95-51-2
官報公示整理番号 METI No. : 3-194
物質名 test material : o-クロロアニリン /o-Chloroaniline
水溶解度 water solubility : 8160mg/L (推計値 estimated)
LogKow : 1.9 (実測値 measured)
備考 remarks
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書) / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし 4:情報が少なく評価不能
日本環境省 化学物質の環境リスク評価(生態リスク初期評価) A:試験は信頼できる B:試験は条件付きで信頼できる C:試験の信頼性は低い D:信頼性の判定不可 E:信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり Supplemental:条件付きで信頼性あり Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり:○
なし:×
情報源 情報源による
信頼性評価**
著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value
exposure
duration
unit
toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material
original work type original work
reliability rank
author title referenced journal publication year Information
update date
藻類 Scenedesmus subspicatus Population EC50 3 days 150000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., and M. Pattard Results of the Harmful Effects of Water Pollutants to Green Algae (Scenedesmus subspicatus) in the Cell Multiplication Inhibition Test Water Res.24(1): 31-38 1990 2016/03/25
藻類 Scenedesmus subspicatus Population EC50 3 days 40000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., and M. Pattard Results of the Harmful Effects of Water Pollutants to Green Algae (Scenedesmus subspicatus) in the Cell Multiplication Inhibition Test Water Res.24(1): 31-38 1990 2016/03/25
藻類 Scenedesmus subspicatus Population EC50 4 days 35000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., and M. Pattard Results of the Harmful Effects of Water Pollutants to Green Algae (Scenedesmus subspicatus) in the Cell Multiplication Inhibition Test Water Res.24(1): 31-38 1990 2016/03/25
藻類 Scenedesmus subspicatus Population EC50 2 days 235000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., and M. Pattard Results of the Harmful Effects of Water Pollutants to Green Algae (Scenedesmus subspicatus) in the Cell Multiplication Inhibition Test Water Res.24(1): 31-38 1990 2016/03/25
藻類 Scenedesmus subspicatus Population NOEC >=250000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Nendza,M., and A. Wenzel Discriminating Toxicant Classes by Mode of Action 1. (Eco)toxicity Profiles Environ. Sci. Pollut. Res.13(3): 192-203 2006 2016/03/25
藻類 Scenedesmus subspicatus Population EC50 2 days 90000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., and M. Pattard Results of the Harmful Effects of Water Pollutants to Green Algae (Scenedesmus subspicatus) in the Cell Multiplication Inhibition Test Water Res.24(1): 31-38 1990 2016/03/25
甲殻類 Daphnia magna Mortality LC50 2 days 130 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Maas-Diepeveen,J.L., and C.J. Van Leeuwen Aquatic Toxicity of Aromatic Nitro Compounds and Anilines to Several Freshwater Species Report No.86-42, Laboratory for Ecotoxicology, Institute for Inland Water Management and Waste Water Treatment:10 p. 1986 2016/03/25
甲殻類 Daphnia magna Mortality LC50 2 days 1500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Canton,J.H., W. Slooff, H.J. Kool, J. Struys, Th.J.M. Pouw, R.C.C. Wegman, and G.J. Piet Toxicity, Biodegradability, and Accumulation of a Number of Cl/N-Containing Compounds for Classification and Establishing Water Quality Criteria Regul. Toxicol. Pharmacol.5:123-131 1985 2016/03/25
甲殻類 Daphnia magna Physiology EC50 1 days 1700 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Pedersen,F., E. Bjornestad, T. Vulpius, and H.B. Rasmussen Immobilisation Test of Aniline Compounds with the Crustacean Daphnia magna Proj.No.303587, Report to the Danish EPA, Copenhagen, Denmark:93 p. 1998 2016/03/25
甲殻類 Daphnia magna Physiology EC50 1 days 6000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., M. Pattard, K.D. Pernak, and A. Winter Results of the Harmful Effects of Water Pollutants to Daphnia magna in the 21 Day Reproduction Test Water Res.23(4): 501-510 1989 2016/03/25
甲殻類 Daphnia magna Physiology EC50 2 days 450 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Pedersen,F., E. Bjornestad, T. Vulpius, and H.B. Rasmussen Immobilisation Test of Aniline Compounds with the Crustacean Daphnia magna Proj.No.303587, Report to the Danish EPA, Copenhagen, Denmark:93 p. 1998 2016/03/25
甲殻類 Daphnia magna Behavior NOEC 21 days 32 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R. Schadstoffwirkungen von Umweltchemikalien im Daphnien-Reproduktions-Test als Grundlage fr die Bewertung der Umweltgefhrlichkeit in Aquatischen Sys Forschungsbericht 10603052, Mrz: 1988 2016/03/25
甲殻類 Daphnia magna Physiology EC50 2 days 1800 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., M. Pattard, K.D. Pernak, and A. Winter Results of the Harmful Effects of Selected Water Pollutants (Anilines, Phenols, Aliphatic Compounds) to Daphnia magna Water Res.23(4): 495-499 1989 2016/03/25
甲殻類 Daphnia magna Reproduction NOEC 21 days 32 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., M. Pattard, K.D. Pernak, and A. Winter Results of the Harmful Effects of Water Pollutants to Daphnia magna in the 21 Day Reproduction Test Water Res.23(4): 501-510 1989 2016/03/25
甲殻類 Daphnia magna Physiology EC50 2 days 460 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Canton,J.H., W. Slooff, H.J. Kool, J. Struys, Th.J.M. Pouw, R.C.C. Wegman, and G.J. Piet Toxicity, Biodegradability, and Accumulation of a Number of Cl/N-Containing Compounds for Classification and Establishing Water Quality Criteria Regul. Toxicol. Pharmacol.5:123-131 1985 2016/03/25
甲殻類 Daphnia magna Physiology EC50 1 days 4200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., M. Pattard, K.D. Pernak, and A. Winter Results of the Harmful Effects of Selected Water Pollutants (Anilines, Phenols, Aliphatic Compounds) to Daphnia magna Water Res.23(4): 495-499 1989 2016/03/25
甲殻類 Daphnia magna Behavior EC0 1 days 1400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R. Schadstoffwirkungen von Umweltchemikalien im Daphnien-Reproduktions-Test als Grundlage fr die Bewertung der Umweltgefhrlichkeit in Aquatischen Sys Forschungsbericht 10603052, Mrz: 1988 2016/03/25
甲殻類 Daphnia magna Behavior EC50 1 days 6000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R. Schadstoffwirkungen von Umweltchemikalien im Daphnien-Reproduktions-Test als Grundlage fr die Bewertung der Umweltgefhrlichkeit in Aquatischen Sys Forschungsbericht 10603052, Mrz: 1988 2016/03/25
甲殻類 Daphnia magna Intoxication ET50 24 hours 5.97 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Urrestarazu Ramos, E. Aquatic toxicity of polar narcotic pollutants/ Mechanism, modeling and environmental effect assessment (PhD Thesis) 1998 2016/02/08
甲殻類 Daphnia magna Intoxication ET50 24 hours 8.62 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Urrestarazu Ramos, E. Aquatic toxicity of polar narcotic pollutants/ Mechanism, modeling and environmental effect assessment (PhD Thesis) 1998 2016/02/08
甲殻類 Daphnia magna Mortality LC50 48 hours 0.824 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Peter C. von der Ohe, Ralph Kühne, Ralf-Uwe Ebert, Rolf Altenburger, Matthias Liess, and Gerrit Schüürmann Structural Alerts-A New Classification Model to Discriminate Excess Toxicity from Narcotic Effect Levels of Organic Compounds in the Acute Daphnid Assay 2005 2016/02/08
甲殻類 Daphnia magna Lethal NOEC 504 hours 0.032 mg/L 9 ECETOC Aquatic Toxicity, EAT Kühn ea 89 2016/02/08
甲殻類 Daphnia magna Lethal LOEC 504 hours 0.101 mg/L 9 ECETOC Aquatic Toxicity, EAT Kühn ea 89 2016/02/08
魚類 Poecilia reticulata (Guppy) Mortality LC50 14 days 6300 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Maas-Diepeveen,J.L., and C.J. Van Leeuwen Aquatic Toxicity of Aromatic Nitro Compounds and Anilines to Several Freshwater Species Report No.86-42, Laboratory for Ecotoxicology, Institute for Inland Water Management and Waste Water Treatment:10 p. 1986 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 5650 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Broderius,S.J., M.D. Kahl, and M.D. Hoglund Use of Joint Toxic Response to Define the Primary Mode of Toxic Action for Diverse Industrial Organic Chemicals Environ. Toxicol. Chem.14(9): 1591-1605 1995 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 5810 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Brooke,L.T., D.J. Call, D.L. Geiger, and C.E. Northcott Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales promelas), Vol. 1 Center for Lake Superior Environmental Studies, University of Wisconsin-Superior, Superior, WI:414 p. 1984 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 4 days 41 μmol/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Zok,S., G. Gorge, W. Kalsch, and R. Nagel Bioconcentration, Metabolism and Toxicity of Substituted Anilines in the Zebrafish (Brachydanio rerio) Sci. Total Environ.109/110:411-421 1991 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Physiology 17.3 hours 1660 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bradbury,S.P., T.R. Henry, G.J. Niemi, R.W. Carlson, and V.M. Snarski Use of Respiratory-Cardiovascular Responses of Rainbow Trout (Salmo gairdneri) in Identifying Acute Toxicity Syndromes in Fish: Part 3. Polar Narcotics Environ. Toxicol. Chem.8(3): 247-261 1989 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality 17.3 hours 1660 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bradbury,S.P., T.R. Henry, G.J. Niemi, R.W. Carlson, and V.M. Snarski Use of Respiratory-Cardiovascular Responses of Rainbow Trout (Salmo gairdneri) in Identifying Acute Toxicity Syndromes in Fish: Part 3. Polar Narcotics Environ. Toxicol. Chem.8(3): 247-261 1989 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 5680 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Geiger,D.L., S.H. Poirier, L.T. Brooke, and D.J. Call Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales promelas) Volume III Center for Lake Superior Environmental Studies, University of Wisconsin, Superior, WI:328 p. 1986 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC100 2 days 121500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Lysak,A., and J. Marcinek Multiple Toxic Effect of Simultaneous Action of Some Chemical Substances on Fish Rocz. Nauk Roln. Ser. H Rybactwo.94(3): 53-63 1972 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 4 days 5130 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Broderius,S.J., M.D. Kahl, and M.D. Hoglund Use of Joint Toxic Response to Define the Primary Mode of Toxic Action for Diverse Industrial Organic Chemicals Environ. Toxicol. Chem.14(9): 1591-1605 1995 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC0 2 days 14500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Lysak,A., and J. Marcinek Multiple Toxic Effect of Simultaneous Action of Some Chemical Substances on Fish Rocz. Nauk Roln. Ser. H Rybactwo.94(3): 53-63 1972 2016/03/25
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 96 hours 5.7 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Russom, C.L., Bradbury, S.P., Broderius, S.J., Drummond, R.A. and Hammermeister, D.E. PREDICTING MODES OF TOXIC ACTION FROM CHEMICAL STRUCTURE: ACUTE TOXICITY IN THE FATHEAD MINNOW (PIMEPHALES PROMELAS) 1997 2016/02/08
魚類 Oryzias latipes (Japanese medaka) Mortality LC50 48 hours 6.25 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) - Biodegradation and Bioaccumulation Data of Existing Chemicals Based on the CSCL Japan 1992 2016/02/08
魚類 Poecilia reticulata (Guppy) Mortality LC50 96 hours 6.25 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Raevsky, O.A., and Dearden, J.C. Creation of predictive models of aquatic toxicity of environmental pollutants with different mechanisms of action on the basis of molecular similarity and hybot descriptors. 2004 2016/02/08