生態影響に係る有害性情報


CAS登録番号 CAS RN ® ： 95-53-4
官報公示整理番号　METI No. ： 3-186
物質名 test material ： ｏ－トルイジン　／o-Toluidine
水溶解度 water solubility ： 16600mg/L (推計値 estimated)
LogKow ： 1.32 (実測値 measured)
備考 remarks ：
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書） / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし　4:情報が少なく評価不能
日本環境省　化学物質の環境リスク評価（生態リスク初期評価） A：試験は信頼できる　B：試験は条件付きで信頼できる　C：試験の信頼性は低い　D：信頼性の判定不可　E：信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり　Supplemental:条件付きで信頼性あり　Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり：○
なし：×		 情報源 情報源による
信頼性評価**		 著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value		 exposure
duration
unit		 toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material		 original work type original work
reliability rank		 author title referenced journal publication year Information
update date
藻類 Scenedesmus subspicatus Population EC50 3 days >8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., and M. Pattard Results of the Harmful Effects of Water Pollutants to Green Algae (Scenedesmus subspicatus) in the Cell Multiplication Inhibition Test Water Res.24(1): 31-38 1990 2016/03/25
藻類 Scenedesmus subspicatus Population EC50 2 days 9500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., and M. Pattard Results of the Harmful Effects of Water Pollutants to Green Algae (Scenedesmus subspicatus) in the Cell Multiplication Inhibition Test Water Res.24(1): 31-38 1990 2016/03/25
藻類 Pseudokirchneriella subcapitata Population 5000000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Hsieh,Y.P., M.B. Tomson, and C.H. Ward Toxicity of Water-Soluble Extracts of No. 2 Fuel Oil to the Freshwater Alga Selenastrum capricornutum Dev. Ind. Microbiol.21:401-409 1980 2016/03/25
藻類 Scenedesmus subspicatus Population EC50 4 days 3700 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., and M. Pattard Results of the Harmful Effects of Water Pollutants to Green Algae (Scenedesmus subspicatus) in the Cell Multiplication Inhibition Test Water Res.24(1): 31-38 1990 2016/03/25
藻類 Scenedesmus subspicatus Population EC50 3 days 3900 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., and M. Pattard Results of the Harmful Effects of Water Pollutants to Green Algae (Scenedesmus subspicatus) in the Cell Multiplication Inhibition Test Water Res.24(1): 31-38 1990 2016/03/25
藻類 Scenedesmus subspicatus Population EC50 2 days >8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kuhn,R., and M. Pattard Results of the Harmful Effects of Water Pollutants to Green Algae (Scenedesmus subspicatus) in the Cell Multiplication Inhibition Test Water Res.24(1): 31-38 1990 2016/03/25
甲殻類 Daphnia magna Behavior EC0 1 days 1600 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuehn Results of Toxic Action of Water Pollutants on Daphnia magna Straus Tested by an Improved Standardized Procedure Z. Wasser-Abwasser-Forsch.15(1): 1-6 1982 2016/03/25
甲殻類 Daphnia magna Behavior EC0 1 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuehn Results of Toxic Action of Water Pollutants on Daphnia magna Straus Tested by an Improved Standardized Procedure Z. Wasser-Abwasser-Forsch.15(1): 1-6 1982 2016/03/25
甲殻類 Daphnia magna Mortality 21 days 1000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Maas-Diepeveen,J.L., and C.J. Van Leeuwen Aquatic Toxicity of Aromatic Nitro Compounds and Anilines to Several Freshwater Species Report No.86-42, Laboratory for Ecotoxicology, Institute for Inland Water Management and Waste Water Treatment:10 p. 1986 2016/03/25
甲殻類 Daphnia magna Behavior EC50 1 days 50000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuehn Results of Toxic Action of Water Pollutants on Daphnia magna Straus Tested by an Improved Standardized Procedure Z. Wasser-Abwasser-Forsch.15(1): 1-6 1982 2016/03/25
甲殻類 Daphnia magna Behavior 2 days 8000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuhn Comparative Water-Toxicological Investigations on Bacteria, Algae, and Daphnia TR-TS-002, Literature Research Company, Annandale, VA:26 p. 1959 2016/03/25
甲殻類 Daphnia magna Mortality LC50 2 days 520 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Maas-Diepeveen,J.L., and C.J. Van Leeuwen Aquatic Toxicity of Aromatic Nitro Compounds and Anilines to Several Freshwater Species Report No.86-42, Laboratory for Ecotoxicology, Institute for Inland Water Management and Waste Water Treatment:10 p. 1986 2016/03/25
甲殻類 Daphnia magna Mortality LC50 21 days 2200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Maas-Diepeveen,J.L., and C.J. Van Leeuwen Aquatic Toxicity of Aromatic Nitro Compounds and Anilines to Several Freshwater Species Report No.86-42, Laboratory for Ecotoxicology, Institute for Inland Water Management and Waste Water Treatment:10 p. 1986 2016/03/25
甲殻類 Daphnia magna Physiology LC50 1 days 26000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuhn Results of the Damaging Effect of Water Pollutants on Daphnia magna (Befunde der Schadwirkung Wassergefahrdender Stoffe Gegen Daphnia magna) TR-79-1204, Literature Research Company, Annandale, VA:26 p. 1977 2016/03/25
甲殻類 Daphnia magna Behavior EC50 1 days 9000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuehn Results of Toxic Action of Water Pollutants on Daphnia magna Straus Tested by an Improved Standardized Procedure Z. Wasser-Abwasser-Forsch.15(1): 1-6 1982 2016/03/25
甲殻類 Daphnia magna Reproduction 21 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Maas-Diepeveen,J.L., and C.J. Van Leeuwen Aquatic Toxicity of Aromatic Nitro Compounds and Anilines to Several Freshwater Species Report No.86-42, Laboratory for Ecotoxicology, Institute for Inland Water Management and Waste Water Treatment:10 p. 1986 2016/03/25
甲殻類 Daphnia magna Behavior EC100 1 days 100000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuehn Results of Toxic Action of Water Pollutants on Daphnia magna Straus Tested by an Improved Standardized Procedure Z. Wasser-Abwasser-Forsch.15(1): 1-6 1982 2016/03/25
甲殻類 Daphnia magna Physiology LC100 1 days 60000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuhn Results of the Damaging Effect of Water Pollutants on Daphnia magna (Befunde der Schadwirkung Wassergefahrdender Stoffe Gegen Daphnia magna) TR-79-1204, Literature Research Company, Annandale, VA:26 p. 1977 2016/03/25
甲殻類 Daphnia magna Behavior EC100 1 days 100000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuehn Results of Toxic Action of Water Pollutants on Daphnia magna Straus Tested by an Improved Standardized Procedure Z. Wasser-Abwasser-Forsch.15(1): 1-6 1982 2016/03/25
甲殻類 Daphnia magna Physiology LC0 1 days 2500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Bringmann,G., and R. Kuhn Results of the Damaging Effect of Water Pollutants on Daphnia magna (Befunde der Schadwirkung Wassergefahrdender Stoffe Gegen Daphnia magna) TR-79-1204, Literature Research Company, Annandale, VA:26 p. 1977 2016/03/25
甲殻類 Daphnia magna Mortality LC50 48 hours 0.525 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Peter C. von der Ohe, Ralph Kühne, Ralf-Uwe Ebert, Rolf Altenburger, Matthias Liess, and Gerrit Schüürmann Structural Alerts-A New Classification Model to Discriminate Excess Toxicity from Narcotic Effect Levels of Organic Compounds in the Acute Daphnid Assay 2005 2016/02/08
甲殻類 Daphnia magna Reproduction NOEC 504 hours 0.16 mg/L 9 ECETOC Aquatic Toxicity, EAT Kühn ea 89 2016/02/08
甲殻類 Daphnia magna Reproduction LOEC 504 hours 0.32 mg/L 9 ECETOC Aquatic Toxicity, EAT Kühn ea 89 2016/02/08
魚類 Poecilia reticulata (Guppy) Mortality LC50 14 days 81300 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Maas-Diepeveen,J.L., and C.J. Van Leeuwen Aquatic Toxicity of Aromatic Nitro Compounds and Anilines to Several Freshwater Species Report No.86-42, Laboratory for Ecotoxicology, Institute for Inland Water Management and Waste Water Treatment:10 p. 1986 2016/03/25
魚類 Carassius auratus (Goldfish) Mortality LC50 2 days 124000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tonogai,Y., S. Ogawa, Y. Ito, and M. Iwaida Studies of the Syncopic Effect of Aniline Derivatives on Fish. I. The Problem Concerning the Determination of Median Lethal Concentration Eisei Kagaku29(5): 280-285 1983 2016/03/25
魚類 Leuciscus idus (Orfe) Mortality LC50 96 hours 117 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Furusjö, E., Andersson, M., Rahmberg, M., Svenson, A. Estimating environmentally important properties of chemicals from the chemical structure 2003 2016/02/08
魚類 Pimephales promelas (Fathead minnow) Mortality LC50 96 hours 81.3 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Urrestarazu Ramos, E. Aquatic toxicity of polar narcotic pollutants/ Mechanism, modeling and environmental effect assessment (PhD Thesis) 1998 2016/02/08
魚類 Poecilia reticulata (Guppy) Mortality LC50 96 hours 81.3 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Raevsky, O.A., and Dearden, J.C. Creation of predictive models of aquatic toxicity of environmental pollutants with different mechanisms of action on the basis of molecular similarity and hybot descriptors. 2004 2016/02/08