生態影響に係る有害性情報


CAS登録番号 CAS RN ® : 97-77-8
官報公示整理番号 METI No. : 2-1820
物質名 test material : テトラエチルチウラム=ジスルフィド /Tetraethylthiuram disulfide
水溶解度 water solubility : 4.09mg/L (推計値 estimated)
LogKow : 3.88 (実測値 measured)
備考 remarks
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書) / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし 4:情報が少なく評価不能
日本環境省 化学物質の環境リスク評価(生態リスク初期評価) A:試験は信頼できる B:試験は条件付きで信頼できる C:試験の信頼性は低い D:信頼性の判定不可 E:信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり Supplemental:条件付きで信頼性あり Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり:○
なし:×
情報源 情報源による
信頼性評価**
著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value
exposure
duration
unit
toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material
original work type original work
reliability rank
author title referenced journal publication year Information
update date
甲殻類 Daphnia magna Mortality LC50 21 days 12 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., F. Moberts, and G. Niebeek Aquatic Toxicological Aspects of Dithiocarbamates and Related Compounds. II. Effects on Survival, Reproduction and Growth of Daphnia magna Aquat. Toxicol.7:165-175 1988 2016/03/25
甲殻類 Daphnia magna Mortality LC50 2 days 120 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., J.L. Maas-Diepeveen, G. Niebeek, W.H.A. Vergouw, P.S. Griffioen, and M.W. Luijken Aquatic Toxicological Aspects of Dithiocarbamates and Related Compounds. I. Short-Term Toxicity Tests Aquat. Toxicol.7(3): 145-164 1985 2016/03/25
甲殻類 Daphnia magna Mortality LC50 48 hours 0.817 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Peter C. von der Ohe, Ralph Kühne, Ralf-Uwe Ebert, Rolf Altenburger, Matthias Liess, and Gerrit Schüürmann Structural Alerts-A New Classification Model to Discriminate Excess Toxicity from Narcotic Effect Levels of Organic Compounds in the Acute Daphnid Assay 2005 2016/02/08
魚類 Oncorhynchus mykiss (Rainbow trout) No Group Code EC50 60 days 6.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates and Related Compounds. III. Embryolarval Studies with Rainbow Trout (Salmo gairdneri) Aquat. Toxicol.9(2/3): 129-145 1986 2016/03/25
魚類 Danio rerio (Zebrafish) Growth EC50 7 days 130 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LC50 60 days 9 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates and Related Compounds. III. Embryolarval Studies with Rainbow Trout (Salmo gairdneri) Aquat. Toxicol.9(2/3): 129-145 1986 2016/03/25
魚類 Poecilia reticulata (Guppy) Mortality LC50 4 days 320 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., J.L. Maas-Diepeveen, G. Niebeek, W.H.A. Vergouw, P.S. Griffioen, and M.W. Luijken Aquatic Toxicological Aspects of Dithiocarbamates and Related Compounds. I. Short-Term Toxicity Tests Aquat. Toxicol.7(3): 145-164 1985 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Growth LOEC 60 days 3.2 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates and Related Compounds. III. Embryolarval Studies with Rainbow Trout (Salmo gairdneri) Aquat. Toxicol.9(2/3): 129-145 1986 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) No Group Code LOEC 60 days 5.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates and Related Compounds. III. Embryolarval Studies with Rainbow Trout (Salmo gairdneri) Aquat. Toxicol.9(2/3): 129-145 1986 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 20 hours 400~4000 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tilton,F., J.K. La Du, M. Vue, N. Alzarban, and R.L. Tanguay Dithiocarbamates have a Common Toxic Effect on Zebrafish Body Axis Formation Toxicol. Appl. Pharmacol.216(1): 55-68 2006 2016/03/25
魚類 Danio rerio (Zebrafish) Growth LOEL 20 hours 400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tilton,F., J.K. La Du, M. Vue, N. Alzarban, and R.L. Tanguay Dithiocarbamates have a Common Toxic Effect on Zebrafish Body Axis Formation Toxicol. Appl. Pharmacol.216(1): 55-68 2006 2016/03/25
魚類 Danio rerio (Zebrafish) Growth NOEL 20 hours 40 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Tilton,F., J.K. La Du, M. Vue, N. Alzarban, and R.L. Tanguay Dithiocarbamates have a Common Toxic Effect on Zebrafish Body Axis Formation Toxicol. Appl. Pharmacol.216(1): 55-68 2006 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LC50 7 days 2200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Mortality LOEC 60 days 5.6 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates and Related Compounds. III. Embryolarval Studies with Rainbow Trout (Salmo gairdneri) Aquat. Toxicol.9(2/3): 129-145 1986 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Growth LOEC 60 days 1.8 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., A. Espeldoorn, and F. Mol Aquatic Toxicological Aspects of Dithiocarbamates and Related Compounds. III. Embryolarval Studies with Rainbow Trout (Salmo gairdneri) Aquat. Toxicol.9(2/3): 129-145 1986 2016/03/25
魚類 Danio rerio (Zebrafish) Mortality LOEC 7 days 320 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2016/03/25
魚類 Danio rerio (Zebrafish) No Group Code LOEC 7 days 320 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds Ecotoxicol. Environ. Saf.20(1): 42-52 1990 2016/03/25
魚類 Oncorhynchus mykiss (Rainbow trout) Cellular Effects 30 days 100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Van Leeuwen,C.J., T. Helder, and W. Seinen Aquatic Toxicological Aspects of Dithiocarbamates and Related Compounds. IV. Teratogenicity and Histopathology in Rainbow Trout (Salmo gairdneri) Aquat. Toxicol.9(2/3): 147-159 1986 2016/03/25
魚類 Poecilia reticulata (Guppy) Mortality LC50 96 hours 0.00664 mg/L 17 Aquatic OASIS (OECD QSAR Toolbox) Raevsky, O.A., and Dearden, J.C. Creation of predictive models of aquatic toxicity of environmental pollutants with different mechanisms of action on the basis of molecular similarity and hybot descriptors. 2004 2016/02/08