【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。
生物種 | 学名 | 影響内容 | エンドポイント | 暴露期間(値) | 暴露期間(単位) | 毒性値 | 毒性値(単位) | 毒性値(単位)種別 | 試験中の 被験物質 濃度測定 あり:○ なし:× |
情報源 | 情報源による 信頼性評価** |
著者 | タイトル | 記載誌 | 発行年 | 情報更新日 | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
subject type | scientific name | effect | endpoint | exposure duration value |
exposure duration unit |
toxicity value | toxicity unit | toxicity unit type | Read-across* | QSAR | GLP | measurement of the test material |
original work type | original work reliability rank |
author | title | referenced journal | publication year | Information update date |
甲殻類 | Daphnia magna | Mortality | LC50 | 21 | days | 12 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., F. Moberts, and G. Niebeek | Aquatic Toxicological Aspects of Dithiocarbamates and Related Compounds. II. Effects on Survival, Reproduction and Growth of Daphnia magna | Aquat. Toxicol.7:165-175 | 1988 | 2016/03/25 | ||||||
甲殻類 | Daphnia magna | Mortality | LC50 | 2 | days | 120 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., J.L. Maas-Diepeveen, G. Niebeek, W.H.A. Vergouw, P.S. Griffioen, and M.W. Luijken | Aquatic Toxicological Aspects of Dithiocarbamates and Related Compounds. I. Short-Term Toxicity Tests | Aquat. Toxicol.7(3): 145-164 | 1985 | 2016/03/25 | ||||||
甲殻類 | Daphnia magna | Mortality | LC50 | 48 | hours | 0.817 | mg/L | 17 Aquatic OASIS (OECD QSAR Toolbox) | Peter C. von der Ohe, Ralph Kühne, Ralf-Uwe Ebert, Rolf Altenburger, Matthias Liess, and Gerrit Schüürmann | Structural Alerts-A New Classification Model to Discriminate Excess Toxicity from Narcotic Effect Levels of Organic Compounds in the Acute Daphnid Assay | 2005 | 2016/02/08 | |||||||
魚類 | Oncorhynchus mykiss (Rainbow trout) | No Group Code | EC50 | 60 | days | 6.2 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., A. Espeldoorn, and F. Mol | Aquatic Toxicological Aspects of Dithiocarbamates and Related Compounds. III. Embryolarval Studies with Rainbow Trout (Salmo gairdneri) | Aquat. Toxicol.9(2/3): 129-145 | 1986 | 2016/03/25 | ||||||
魚類 | Danio rerio (Zebrafish) | Growth | EC50 | 7 | days | 130 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek | Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds | Ecotoxicol. Environ. Saf.20(1): 42-52 | 1990 | 2016/03/25 | ||||||
魚類 | Oncorhynchus mykiss (Rainbow trout) | Mortality | LC50 | 60 | days | 9 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., A. Espeldoorn, and F. Mol | Aquatic Toxicological Aspects of Dithiocarbamates and Related Compounds. III. Embryolarval Studies with Rainbow Trout (Salmo gairdneri) | Aquat. Toxicol.9(2/3): 129-145 | 1986 | 2016/03/25 | ||||||
魚類 | Poecilia reticulata (Guppy) | Mortality | LC50 | 4 | days | 320 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., J.L. Maas-Diepeveen, G. Niebeek, W.H.A. Vergouw, P.S. Griffioen, and M.W. Luijken | Aquatic Toxicological Aspects of Dithiocarbamates and Related Compounds. I. Short-Term Toxicity Tests | Aquat. Toxicol.7(3): 145-164 | 1985 | 2016/03/25 | ||||||
魚類 | Oncorhynchus mykiss (Rainbow trout) | Growth | LOEC | 60 | days | 3.2 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., A. Espeldoorn, and F. Mol | Aquatic Toxicological Aspects of Dithiocarbamates and Related Compounds. III. Embryolarval Studies with Rainbow Trout (Salmo gairdneri) | Aquat. Toxicol.9(2/3): 129-145 | 1986 | 2016/03/25 | ||||||
魚類 | Oncorhynchus mykiss (Rainbow trout) | No Group Code | LOEC | 60 | days | 5.6 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., A. Espeldoorn, and F. Mol | Aquatic Toxicological Aspects of Dithiocarbamates and Related Compounds. III. Embryolarval Studies with Rainbow Trout (Salmo gairdneri) | Aquat. Toxicol.9(2/3): 129-145 | 1986 | 2016/03/25 | ||||||
魚類 | Danio rerio (Zebrafish) | Mortality | LC50 | 20 | hours | 400~4000 | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Tilton,F., J.K. La Du, M. Vue, N. Alzarban, and R.L. Tanguay | Dithiocarbamates have a Common Toxic Effect on Zebrafish Body Axis Formation | Toxicol. Appl. Pharmacol.216(1): 55-68 | 2006 | 2016/03/25 | |||||||
魚類 | Danio rerio (Zebrafish) | Growth | LOEL | 20 | hours | 400 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Tilton,F., J.K. La Du, M. Vue, N. Alzarban, and R.L. Tanguay | Dithiocarbamates have a Common Toxic Effect on Zebrafish Body Axis Formation | Toxicol. Appl. Pharmacol.216(1): 55-68 | 2006 | 2016/03/25 | ||||||
魚類 | Danio rerio (Zebrafish) | Growth | NOEL | 20 | hours | 40 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Tilton,F., J.K. La Du, M. Vue, N. Alzarban, and R.L. Tanguay | Dithiocarbamates have a Common Toxic Effect on Zebrafish Body Axis Formation | Toxicol. Appl. Pharmacol.216(1): 55-68 | 2006 | 2016/03/25 | ||||||
魚類 | Danio rerio (Zebrafish) | Mortality | LC50 | 7 | days | 2200 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek | Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds | Ecotoxicol. Environ. Saf.20(1): 42-52 | 1990 | 2016/03/25 | ||||||
魚類 | Oncorhynchus mykiss (Rainbow trout) | Mortality | LOEC | 60 | days | 5.6 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., A. Espeldoorn, and F. Mol | Aquatic Toxicological Aspects of Dithiocarbamates and Related Compounds. III. Embryolarval Studies with Rainbow Trout (Salmo gairdneri) | Aquat. Toxicol.9(2/3): 129-145 | 1986 | 2016/03/25 | ||||||
魚類 | Oncorhynchus mykiss (Rainbow trout) | Growth | LOEC | 60 | days | 1.8 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., A. Espeldoorn, and F. Mol | Aquatic Toxicological Aspects of Dithiocarbamates and Related Compounds. III. Embryolarval Studies with Rainbow Trout (Salmo gairdneri) | Aquat. Toxicol.9(2/3): 129-145 | 1986 | 2016/03/25 | ||||||
魚類 | Danio rerio (Zebrafish) | Mortality | LOEC | 7 | days | 320 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek | Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds | Ecotoxicol. Environ. Saf.20(1): 42-52 | 1990 | 2016/03/25 | ||||||
魚類 | Danio rerio (Zebrafish) | No Group Code | LOEC | 7 | days | 320 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., E.M.M. Grootelaar, and G. Niebeek | Fish Embryos as Teratogenicity Screens: A Comparison of Embryotoxicity Between Fish and Birds | Ecotoxicol. Environ. Saf.20(1): 42-52 | 1990 | 2016/03/25 | ||||||
魚類 | Oncorhynchus mykiss (Rainbow trout) | Cellular Effects | 30 | days | 100 | μg/L | 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) | Van Leeuwen,C.J., T. Helder, and W. Seinen | Aquatic Toxicological Aspects of Dithiocarbamates and Related Compounds. IV. Teratogenicity and Histopathology in Rainbow Trout (Salmo gairdneri) | Aquat. Toxicol.9(2/3): 147-159 | 1986 | 2016/03/25 | |||||||
魚類 | Poecilia reticulata (Guppy) | Mortality | LC50 | 96 | hours | 0.00664 | mg/L | 17 Aquatic OASIS (OECD QSAR Toolbox) | Raevsky, O.A., and Dearden, J.C. | Creation of predictive models of aquatic toxicity of environmental pollutants with different mechanisms of action on the basis of molecular similarity and hybot descriptors. | 2004 | 2016/02/08 |