生態影響に係る有害性情報


CAS登録番号 CAS RN ® : 99-76-3
官報公示整理番号 METI No. : 3-1585
物質名 test material : メチル=4-ヒドロキシベンゾアート /Methyl 4-hydroxybenzoate
水溶解度 water solubility : 2500mg/L (推計値 estimated)
LogKow : 1.96 (実測値 measured)
備考 remarks
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【注意事項】
* 生態影響に係る有害性情報更新日が2019年9月以前はRead-acrossデータに○を記載しておらず、被験物質が標記の物質ではない可能性がある。
**各情報源における信頼性評価スコアの定義は下記のとおりである。

OECD SIDS (HPVC) / EU Risk Assessment Report (EUリスク評価書) / ECHA Information on Registered Substances 1:信頼性あり 2:条件付きで信頼性あり 3:信頼性なし 4:情報が少なく評価不能
日本環境省 化学物質の環境リスク評価(生態リスク初期評価) A:試験は信頼できる B:試験は条件付きで信頼できる C:試験の信頼性は低い D:信頼性の判定不可 E:信頼性は低くないと考えられるが、原著にあたって確認したものではない
USEPA Pesticide Ecotoxicity Database Core:信頼性あり Supplemental:条件付きで信頼性あり Invalid:信頼性なし
生物種 学名 影響内容 エンドポイント 暴露期間(値) 暴露期間(単位) 毒性値 毒性値(単位) 毒性値(単位)種別 試験中の
被験物質
濃度測定
あり:○
なし:×
情報源 情報源による
信頼性評価**
著者 タイトル 記載誌 発行年 情報更新日
subject type scientific name effect endpoint exposure
duration
value
exposure
duration
unit
toxicity value toxicity unit toxicity unit type Read-across* QSAR GLP measurement
of the test
material
original work type original work
reliability rank
author title referenced journal publication year Information
update date
藻類 Pseudokirchneriella subcapitata Population EC50 3 days 15000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
藻類 Pseudokirchneriella subcapitata Population EC50 3 days 91000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
藻類 Pseudokirchneriella subcapitata Population EC10 3 days 31000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
藻類 Pseudokirchneriella subcapitata Population EC10 3 days 7000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
藻類 Pseudokirchneriella subcapitata Population NOEC 3 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
藻類 Pseudokirchneriella subcapitata Population NOEC 3 days 20000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
藻類 Pseudokirchneriella subcapitata Population LOEC 3 days 50000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
藻類 Pseudokirchneriella subcapitata Population LOEC 3 days 10000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
藻類 Raphidocelis subcapitata growth rate EC90 72 hours >200 mg/L nominal test mat. 12 ECHA Information on Registered Substances 2 Madsen, T. , Boyd, H. B. , Nylen, D. , Pedersen, A. R. , Pedersen, G. I. , Simonsen, F. Environmental and health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Danish Environmental Protection Agency, Environmental project No. 615 2001, Miljoprojekt. CETOX (Centre for Integrated Environment and Toxicology). 2001 2022/08/10
藻類 Raphidocelis subcapitata Population/Population growth rate EC90 72 hours 32 Formulation × 16 ECOTOX Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615 2022/09/15
藻類 Raphidocelis subcapitata Population/Population growth rate EC90 72 hours >200 Formulation × 16 ECOTOX Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615 2022/09/15
藻類 Raphidocelis subcapitata Population/Population growth rate EC50 72 hours 15 mg/L Formulation × 16 ECOTOX Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615 2001 2022/09/15
藻類 Raphidocelis subcapitata growth rate EC50 72 hours 91 mg/L nominal test mat. 12 ECHA Information on Registered Substances 2 Madsen, T. , Boyd, H. B. , Nylen, D. , Pedersen, A. R. , Pedersen, G. I. , Simonsen, F. Environmental and health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Danish Environmental Protection Agency, Environmental project No. 615 2001, Miljoprojekt. CETOX (Centre for Integrated Environment and Toxicology). 2001 2022/08/10
藻類 Raphidocelis subcapitata Population/Population growth rate EC50 72 hours 91 mg/L Formulation × 16 ECOTOX Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615 2001 2022/09/15
藻類 Raphidocelis subcapitata growth (RATE) EC50 3 days 55600 µg/L 6 日本環境省 化学物質の環境リスク評価(生態リスク初期評価) A 国立環境研究所 平成30 年度化学物質環境リスク初期評価等実施業務報告書 2022/07/21
藻類 Raphidocelis subcapitata growth (RATE) EC50 3 days 35250 µg/L 6 日本環境省 化学物質の環境リスク評価(生態リスク初期評価) C Di Poi, C. K. Costil, V. Bouchart, and M.P. Halm-Lemeille Toxicity Assessment of Five Emerging Pollutants, Alone and in Binary or Ternary Mixtures, towards Three Aquatic Organisms Environmental Science and Pollution Research, 25(7) 2022/07/21
藻類 Raphidocelis subcapitata Population/Population growth rate EC50 48 hours 78 Active ingredient × 16 ECOTOX Kusk,K.O., A.M. Christensen, and N. Nyholm Algal Growth Inhibition Test Results of 425 Organic Chemical Substances Chemosphere204 2022/09/15
藻類 Raphidocelis subcapitata growth EC50 3 days 91000 µg/L 6 日本環境省 化学物質の環境リスク評価(生態リスク初期評価) B Madsen,T., H.B. Boyd, D. Mylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environ.and Energy, Danish EPA, Environ.Proj.No.615 2022/07/21
藻類 Raphidocelis subcapitata growth (RATE) EC50 3 days 80000 µg/L 6 日本環境省 化学物質の環境リスク評価(生態リスク初期評価) A Yamamoto, H., I. Tamura, Y. Hirata, J. Kato, K. Kagota, S. Katsuki, A. Yamamoto, Y. Kagami, and N. Tatarazako Aquatic Toxicity and Ecological Risk Assessment of Seven Parabens: Individual and Additive Approach Sci. Total Environ. 410-411 2022/07/21
藻類 Pseudokirchneriella subcapitata EC50 72 hours 56 mg/L 1 日本環境省 生態リスク初期評価 環境省 (Ⅱ-1)生態影響試験(藻類、甲殻類、魚類)結果一覧(平成28年3月版) 2016 2016/11/08
藻類 Pseudokirchneriella subcapitata EC50 72 hours 30 mg/L 1 日本環境省 生態リスク初期評価 環境省 (Ⅱ-1)生態影響試験(藻類、甲殻類、魚類)結果一覧(平成28年3月版) 2016 2016/11/08
藻類 Pseudokirchneriella subcapitata growth rate EC50 72 hours 91 mg/L 12 ECHA Information on Registered Substances 2 Madsen, T. , Boyd, H. B. , Nylen, D. , Pedersen, A. R. , Pedersen, G. I. , Simonsen, F. Environmental and health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Danish Environmental Protection Agency, Environmental project No. 615 2001, Miljoprojekt. CETOX (Centre for Integrated Environment and Toxicology). 2001 2017/02/19
藻類 Raphidocelis subcapitata Population/Population growth rate NOEC 72 hours 5 mg/L Formulation × 16 ECOTOX Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615 2001 2022/09/15
藻類 Raphidocelis subcapitata growth rate LOEC 72 hours 50 mg/L nominal test mat. 12 ECHA Information on Registered Substances 2 Madsen, T. , Boyd, H. B. , Nylen, D. , Pedersen, A. R. , Pedersen, G. I. , Simonsen, F. Environmental and health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Danish Environmental Protection Agency, Environmental project No. 615 2001, Miljoprojekt. CETOX (Centre for Integrated Environment and Toxicology). 2001 2022/08/10
藻類 Raphidocelis subcapitata Population/Population growth rate EC10 72 hours 7 mg/L Formulation × 16 ECOTOX Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615 2001 2022/09/15
藻類 Raphidocelis subcapitata growth rate EC10 72 hours 31 mg/L nominal test mat. 12 ECHA Information on Registered Substances 2 Madsen, T. , Boyd, H. B. , Nylen, D. , Pedersen, A. R. , Pedersen, G. I. , Simonsen, F. Environmental and health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Danish Environmental Protection Agency, Environmental project No. 615 2001, Miljoprojekt. CETOX (Centre for Integrated Environment and Toxicology). 2001 2022/08/10
藻類 Raphidocelis subcapitata Population/Population growth rate NOEC 72 hours 20 mg/L Formulation × 16 ECOTOX Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615 2001 2022/09/15
藻類 Raphidocelis subcapitata Population/Population growth rate LOEC 72 hours 10 mg/L Formulation × 16 ECOTOX Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615 2001 2022/09/15
藻類 Raphidocelis subcapitata Population/Population growth rate EC10 72 hours 31 mg/L Formulation × 16 ECOTOX Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615 2001 2022/09/15
藻類 Raphidocelis subcapitata growth rate NOEC 72 hours 20 mg/L nominal test mat. 12 ECHA Information on Registered Substances 2 Madsen, T. , Boyd, H. B. , Nylen, D. , Pedersen, A. R. , Pedersen, G. I. , Simonsen, F. Environmental and health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Danish Environmental Protection Agency, Environmental project No. 615 2001, Miljoprojekt. CETOX (Centre for Integrated Environment and Toxicology). 2001 2022/08/10
藻類 Raphidocelis subcapitata Population/Population growth rate LOEC 72 hours 50 mg/L Formulation × 16 ECOTOX Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615 2001 2022/09/15
藻類 Raphidocelis subcapitata growth (RATE) NOEC 3 days 16600 µg/L 6 日本環境省 化学物質の環境リスク評価(生態リスク初期評価) A 国立環境研究所 平成30 年度化学物質環境リスク初期評価等実施業務報告書 2022/07/21
藻類 Raphidocelis subcapitata Population/Population growth rate EC10 48 hours 24 Active ingredient × 16 ECOTOX Kusk,K.O., A.M. Christensen, and N. Nyholm Algal Growth Inhibition Test Results of 425 Organic Chemical Substances Chemosphere204 2022/09/15
藻類 Raphidocelis subcapitata growth NOEC 3 days 20000 µg/L 6 日本環境省 化学物質の環境リスク評価(生態リスク初期評価) B Madsen,T., H.B. Boyd, D. Mylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environ.and Energy, Danish EPA, Environ.Proj.No.615 2022/07/21
藻類 Raphidocelis subcapitata growth (RATE) NOEC 3 days 21000 µg/L 6 日本環境省 化学物質の環境リスク評価(生態リスク初期評価) A Yamamoto, H., I. Tamura, Y. Hirata, J. Kato, K. Kagota, S. Katsuki, A. Yamamoto, Y. Kagami, and N. Tatarazako Aquatic Toxicity and Ecological Risk Assessment of Seven Parabens: Individual and Additive Approach Sci. Total Environ. 410-411 2022/07/21
藻類 Pseudokirchneriella subcapitata growth rate NOEC 72 hours 20 mg/L 12 ECHA Information on Registered Substances 2 Madsen, T. , Boyd, H. B. , Nylen, D. , Pedersen, A. R. , Pedersen, G. I. , Simonsen, F. Environmental and health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Danish Environmental Protection Agency, Environmental project No. 615 2001, Miljoprojekt. CETOX (Centre for Integrated Environment and Toxicology). 2001 2017/02/19
藻類 Pseudokirchneriella subcapitata NOEC 72 hours 17 mg/L 1 日本環境省 生態リスク初期評価 環境省 (Ⅱ-1)生態影響試験(藻類、甲殻類、魚類)結果一覧(平成28年3月版) 2016 2016/11/08
藻類 Pseudokirchneriella subcapitata NOEC 72 hours 17 mg/L 1 日本環境省 生態リスク初期評価 環境省 (Ⅱ-1)生態影響試験(藻類、甲殻類、魚類)結果一覧(平成28年3月版) 2016 2016/11/08
藻類 Pseudokirchneriella subcapitata growth rate LOEC 72 hours 50 mg/L 12 ECHA Information on Registered Substances 2 Madsen, T. , Boyd, H. B. , Nylen, D. , Pedersen, A. R. , Pedersen, G. I. , Simonsen, F. Environmental and health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Danish Environmental Protection Agency, Environmental project No. 615 2001, Miljoprojekt. CETOX (Centre for Integrated Environment and Toxicology). 2001 2017/02/19
藻類 Pseudokirchneriella subcapitata growth rate EC10 72 hours 31 mg/L 12 ECHA Information on Registered Substances 2 Madsen, T. , Boyd, H. B. , Nylen, D. , Pedersen, A. R. , Pedersen, G. I. , Simonsen, F. Environmental and health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Danish Environmental Protection Agency, Environmental project No. 615 2001, Miljoprojekt. CETOX (Centre for Integrated Environment and Toxicology). 2001 2017/02/19
甲殻類 Daphnia magna Physiology EC10 2 days 4500 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
甲殻類 Daphnia magna Physiology EC50 1 days 11400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
甲殻類 Daphnia magna Physiology EC50 1 days 70000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kamaya,Y., Y. Fukaya, and K. Suzuki Acute Toxicity of Benzoic Acids to the Crustacean Daphnia magna Chemosphere59(2): 255-261 2005 2017/03/15
甲殻類 Daphnia magna Physiology EC10 1 days 6240 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
甲殻類 Daphnia magna Physiology EC50 2 days 11200 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
甲殻類 Daphnia magna Physiology NOEC 2 days 2000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
甲殻類 Daphnia magna Physiology LOEC 2 days 5000 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615:235 p. 2001 2017/03/15
甲殻類 Daphnia magna Physiology EC50 2 days 41100 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Kamaya,Y., Y. Fukaya, and K. Suzuki Acute Toxicity of Benzoic Acids to the Crustacean Daphnia magna Chemosphere59(2): 255-261 2005 2017/03/15
甲殻類 Daphnia magna mobility EC90 24 hours 80.7 mg/L nominal test mat. 12 ECHA Information on Registered Substances 2 publication 2001 2022/08/10
甲殻類 Daphnia magna mobility EC50 24 hours 22.4 mg/L nominal test mat. 12 ECHA Information on Registered Substances 2 publication 2001 2022/08/10
甲殻類 Daphnia magna Immobilization EC50 2 days 36730 µg/L 6 日本環境省 化学物質の環境リスク評価(生態リスク初期評価) B Lee, J., Nayeon Park. Younglim Kho, Kiyoung Lee, and Kyunghee Ji Phototoxicity and Chronic Toxicity of Methyl Paraben and 1,2-hexanediol in Daphnia magna Ecotoxicology, 26(1) 2022/07/21
甲殻類 Daphnia magna mobility EC10 24 hours 6.24 mg/L nominal test mat. 12 ECHA Information on Registered Substances 2 publication 2001 2022/08/10
甲殻類 Daphnia magna mobility EC50 48 hours 11.2 mg/L nominal test mat. 12 ECHA Information on Registered Substances 2 publication 2001 2022/08/10
甲殻類 Daphnia magna Intoxication/Immobile LOEC 48 hours 15 Formulation × 16 ECOTOX Bazin,I., A. Gadal, E. Touraud, and B. Roig Hydroxy Benzoate Preservatives (Parabens) in the Environment: Data for Environmental Toxicity Assessment In: Xenobiotics in the Urban Water Cycle: Mass Flows, Environmental Processes, Mitigation and Treatment Strategies 2022/09/15
甲殻類 Daphnia magna mobility EC90 48 hours 27.8 mg/L nominal test mat. 12 ECHA Information on Registered Substances 2 publication 2001 2022/08/10
甲殻類 Daphnia magna Intoxication/Immobile EC50 24 hours 70 mg/L Active ingredient × 16 ECOTOX Kamaya,Y., Y. Fukaya, and K. Suzuki Acute Toxicity of Benzoic Acids to the Crustacean Daphnia magna Chemosphere59(2) 2005 2022/09/15
甲殻類 Daphnia magna Intoxication/Immobile EC50 48 hours 41.1 mg/L Active ingredient × 16 ECOTOX Kamaya,Y., Y. Fukaya, and K. Suzuki Acute Toxicity of Benzoic Acids to the Crustacean Daphnia magna Chemosphere59(2) 2005 2022/09/15
甲殻類 Daphnia magna Intoxication/Immobile EC50 24 hours 11.4 mg/L Formulation × 16 ECOTOX Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615 2001 2022/09/15
甲殻類 Daphnia magna Intoxication/Immobile EC10 48 hours 4.5 mg/L Formulation × 16 ECOTOX Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615 2001 2022/09/15
甲殻類 Daphnia magna Immobilization EC50 2 days 11200 µg/L 6 日本環境省 化学物質の環境リスク評価(生態リスク初期評価) B Madsen,T., H.B. Boyd, D. Mylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environ.and Energy, Danish EPA, Environ.Proj.No.615 2022/07/21
甲殻類 Daphnia magna mobility EC10 48 hours 4.5 mg/L nominal test mat. 12 ECHA Information on Registered Substances 2 publication 2001 2022/08/10
甲殻類 Daphnia magna Intoxication/Immobile NOEC 48 hours 2 mg/L Formulation × 16 ECOTOX Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615 2001 2022/09/15
甲殻類 Daphnia magna Intoxication/Immobile EC50 48 hours 11.2 mg/L Formulation × 16 ECOTOX Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615 2001 2022/09/15
甲殻類 Daphnia magna Intoxication/Immobile LOEC 48 hours 5 mg/L Formulation × 16 ECOTOX Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615 2001 2022/09/15
甲殻類 Daphnia magna Intoxication/Immobile EC10 24 hours 6.24 mg/L Formulation × 16 ECOTOX Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615 2001 2022/09/15
甲殻類 Daphnia magna Intoxication/Immobile EC90 48 hours 27.8 Formulation × 16 ECOTOX Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615 2022/09/15
甲殻類 Daphnia magna Intoxication/Immobile EC50 48 hours 21 Formulation × 16 ECOTOX Bazin,I., A. Gadal, E. Touraud, and B. Roig Hydroxy Benzoate Preservatives (Parabens) in the Environment: Data for Environmental Toxicity Assessment In: Xenobiotics in the Urban Water Cycle: Mass Flows, Environmental Processes, Mitigation and Treatment Strategies 2022/09/15
甲殻類 Daphnia magna Intoxication/Immobile EC90 24 hours 80.7 Formulation × 16 ECOTOX Madsen,T., H.B. Boyd, D. Nylen, A.R. Pedersen, G.I. Petersen, and F. Simonsen Environmental and Health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Ministry of the Environment and Energy, Danish EPA, Environmental Project No.615 2022/09/15
甲殻類 Daphnia magna Immobilization EC50 2 days 35800 µg/L 6 日本環境省 化学物質の環境リスク評価(生態リスク初期評価) A 環境庁 平成11 年度生態影響試験 2022/07/21
甲殻類 Daphnia magna Immobilization EC50 2 days 34000 µg/L 6 日本環境省 化学物質の環境リスク評価(生態リスク初期評価) B Yamamoto, H., I. Tamura, Y. Hirata, J. Kato, K. Kagota, S. Katsuki, A. Yamamoto, Y. Kagami, and N. Tatarazako Aquatic Toxicity and Ecological Risk Assessment of Seven Parabens: Individual and Additive Approach Sci. Total Environ. 410-411 2022/07/21
甲殻類 Daphnia magna Intoxication/Immobile EC50 24 hours 32 Formulation × 16 ECOTOX Bazin,I., A. Gadal, E. Touraud, and B. Roig Hydroxy Benzoate Preservatives (Parabens) in the Environment: Data for Environmental Toxicity Assessment In: Xenobiotics in the Urban Water Cycle: Mass Flows, Environmental Processes, Mitigation and Treatment Strategies 2022/09/15
甲殻類 Daphnia magna Mortality LC50 2 days 24600 µg/L 6 日本環境省 化学物質の環境リスク評価(生態リスク初期評価) B Dobbins,L.L., S. Usenko, R.A. Brain, and B.W. Brooks Probabilistic Ecological Hazard Assessment of Parabens Using Daphnia magna and Pimephales promelas Environ. Toxicol. Chem.28(12) 2022/07/21
甲殻類 Daphnia magna EC50 48 hours 36 mg/L 1 日本環境省 生態リスク初期評価 環境省 (Ⅱ-1)生態影響試験(藻類、甲殻類、魚類)結果一覧(平成28年3月版) 2016 2016/11/08
甲殻類 Daphnia magna mobility EC10 24 hours 6.24 mg/L 12 ECHA Information on Registered Substances 2 publication 2001 2017/02/19
甲殻類 Daphnia magna mobility EC50 24 hours 22.4 mg/L 12 ECHA Information on Registered Substances 2 publication 2001 2017/02/19
甲殻類 Daphnia magna mobility EC10 48 hours 4.5 mg/L 12 ECHA Information on Registered Substances 2 publication 2001 2017/02/19
甲殻類 Daphnia magna mobility EC50 48 hours 11.2 mg/L 12 ECHA Information on Registered Substances 2 publication 2001 2017/02/19
甲殻類 Daphnia magna mobility EC50 48 hours 41.1 mg/L 12 ECHA Information on Registered Substances 2 Kamaya, Y. , Fukaya, Y. , Suzuki, K. Acute toxicity of benzoic acids to the crustacean Daphnia magna Chemosphere 2005 2017/02/07
甲殻類 Ceriodaphnia sp. EC50 48 hours 36 mg/L 12 ECHA Information on Registered Substances 4 publication 1999 2017/02/07
甲殻類 Daphnia magna mobility EC50 24 hours 70 mg/L 12 ECHA Information on Registered Substances 2 Kamaya, Y. , Fukaya, Y. , Suzuki, K. Acute toxicity of benzoic acids to the crustacean Daphnia magna Chemosphere 2005 2017/02/07
甲殻類 Daphnia magna Reproduction NOEC 21 days 2400 µg/L 6 日本環境省 化学物質の環境リスク評価(生態リスク初期評価) B Yamamoto, H., I. Tamura, Y. Hirata, J. Kato, K. Kagota, S. Katsuki, A. Yamamoto, Y. Kagami, and N. Tatarazako Aquatic Toxicity and Ecological Risk Assessment of Seven Parabens: Individual and Additive Approach Sci. Total Environ. 410-411 2022/07/21
甲殻類 Daphnia magna Reproduction NOEC 21 days 200 µg/L 6 日本環境省 化学物質の環境リスク評価(生態リスク初期評価) A 環境庁 平成11 年度生態影響試験 2022/07/21
甲殻類 Daphnia magna Reproduction NOEC 21 days 1000 µg/L 6 日本環境省 化学物質の環境リスク評価(生態リスク初期評価) B Lee, J., Nayeon Park. Younglim Kho, Kiyoung Lee, and Kyunghee Ji Phototoxicity and Chronic Toxicity of Methyl Paraben and 1,2-hexanediol in Daphnia magna Ecotoxicology, 26(1) 2022/07/21
甲殻類 Ceriodaphnia dubia Reproduction NOEC 7 days <1310 µg/L 6 日本環境省 化学物質の環境リスク評価(生態リスク初期評価) B Terasaki, M., R. Abe, M. Makino, and N.Tatarazako Chronic Toxicity of Parabens and Their Chlorinated By-Products in Ceriodaphnia dubia Environ.Toxicol.30(6) 2022/07/21
甲殻類 Daphnia magna NOEC 21 days 0.2 mg/L 1 日本環境省 生態リスク初期評価 環境省 (Ⅱ-1)生態影響試験(藻類、甲殻類、魚類)結果一覧(平成28年3月版) 2016 2016/11/08
甲殻類 Daphnia magna EC50 21 days 5.3 mg/L 1 日本環境省 生態リスク初期評価 環境省 (Ⅱ-1)生態影響試験(藻類、甲殻類、魚類)結果一覧(平成28年3月版) 2016 2016/11/08
甲殻類 Daphnia magna reproduction 21 days 0.8 mg/L 12 ECHA Information on Registered Substances 1 study report 2000 2017/02/07
甲殻類 Daphnia magna mortality EC50 21 days 0.89 mg/L 12 ECHA Information on Registered Substances 1 study report 2000 2017/02/07
甲殻類 Daphnia magna reproduction EC50 21 days 5.32 mg/L 12 ECHA Information on Registered Substances 1 study report 2000 2017/02/07
甲殻類 Daphnia magna reproduction NOEC 21 days 0.2 mg/L 12 ECHA Information on Registered Substances 1 study report 2000 2017/02/07
魚類 Danio rerio (Zebrafish) Growth EC10 2 days 19800 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Schiller,V., A. Wichmann, R. Kriehuber, C. Schafers, R. Fischer, and M. Fenske Transcriptome Alterations in Zebrafish Embryos After Exposure to Environmental Estrogens and Anti-Androgens can Reveal Endocrine Disruption Reprod. Toxicol.42:210-223 2013 2017/03/15
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 2 days 24400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Schiller,V., A. Wichmann, R. Kriehuber, C. Schafers, R. Fischer, and M. Fenske Transcriptome Alterations in Zebrafish Embryos After Exposure to Environmental Estrogens and Anti-Androgens can Reveal Endocrine Disruption Reprod. Toxicol.42:210-223 2013 2017/03/15
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 2 days 24400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Schiller,V., A. Wichmann, R. Kriehuber, C. Schafers, R. Fischer, and M. Fenske Transcriptome Alterations in Zebrafish Embryos After Exposure to Environmental Estrogens and Anti-Androgens can Reveal Endocrine Disruption Reprod. Toxicol.42:210-223 2013 2017/03/15
魚類 Danio rerio (Zebrafish) Cellular Effects LOEC 2 days 24400 μg/L 16 US EPA AQUIRE (AQUatic toxicity Information REtrieval) Schiller,V., A. Wichmann, R. Kriehuber, C. Schafers, R. Fischer, and M. Fenske Transcriptome Alterations in Zebrafish Embryos After Exposure to Environmental Estrogens and Anti-Androgens can Reveal Endocrine Disruption Reprod. Toxicol.42:210-223 2013 2017/03/15
魚類 Leuciscus idus NOEC 48 hours 50 mg/L 12 ECHA Information on Registered Substances 4 Madsen, T. , Boyd, H. B. , Nylen, D. , Pedersen, A. R. , Pedersen, G. I. , Simonsen, F. Environmental and health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Danish Environmental Protection Agency, Environmental project No. 615 2001, Miljoprojekt. CETOX (Centre for Integrated Environment and Toxicology). 2001 2022/08/10
魚類 Oryzias latipes (Japanese medaka) mortality LC50 24 hours >100 mg/L 12 ECHA Information on Registered Substances 1 study report 2000 2017/02/02
魚類 Oryzias latipes (Japanese medaka) mortality LC50 48 hours 79.5 mg/L 12 ECHA Information on Registered Substances 1 study report 2000 2017/02/02
魚類 Oryzias latipes (Japanese medaka) LC50 96 hours 60 mg/L 1 日本環境省 生態リスク初期評価 環境省 (Ⅱ-1)生態影響試験(藻類、甲殻類、魚類)結果一覧(平成28年3月版) 2016 2016/11/08
魚類 Oryzias latipes (Japanese medaka) mortality LC50 96 hours 59.5 mg/L 12 ECHA Information on Registered Substances 1 study report 2000 2017/02/02
魚類 Oryzias latipes (Japanese medaka) mortality LC50 72 hours 70.6 mg/L 12 ECHA Information on Registered Substances 1 study report 2000 2017/02/02
魚類 Leuciscus idus (Orfe) NOEC 48 hours 50 mg/L 12 ECHA Information on Registered Substances 4 Madsen, T. , Boyd, H. B. , Nylen, D. , Pedersen, A. R. , Pedersen, G. I. , Simonsen, F. Environmental and health Assessment of Substances in Household Detergents and Cosmetic Detergent Products Danish Environmental Protection Agency, Environmental project No. 615 2001, Miljoprojekt. CETOX (Centre for Integrated Environment and Toxicology). 2001 2017/02/07
魚 類 Pimephales promelas Mortality LC50 2 days >160000 µg/L 6 日本環境省 化学物質の環境リスク評価(生態リスク初期評価) B Dobbins,L.L., S. Usenko, R.A. Brain, and B.W. Brooks Probabilistic Ecological Hazard Assessment of Parabens Using Daphnia magna and Pimephales promelas Environ. Toxicol. Chem.28(12) 2022/07/21
魚 類 Oryzias latipes Mortality LC50 4 days 63000 µg/L 6 日本環境省 化学物質の環境リスク評価(生態リスク初期評価) B Yamamoto, H., I. Tamura, Y. Hirata, J. Kato, K. Kagota, S. Katsuki, A. Yamamoto, Y. Kagami, and N. Tatarazako Aquatic Toxicity and Ecological Risk Assessment of Seven Parabens: Individual and Additive Approach Sci. Total Environ. 410-411 2022/07/21
魚 類 Oryzias latipes Mortality LC50 4 days 59500 µg/L 6 日本環境省 化学物質の環境リスク評価(生態リスク初期評価) A 環境庁 平成11 年度生態影響試験 2022/07/21